mizukami yuuya 水上優哉

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Mizukami Yuya 水上優哉

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Researcher Number	20881163
Other IDs
Affiliation (Current)	2025: 近畿大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 近畿大学, 医学部, 講師 2020 – 2023: 近畿大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / 0906:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 骨代謝 / 細胞外小胞 / 骨再生 / 老化 / 性ホルモン / 原発性骨粗鬆症 / 石灰化 / 骨粗鬆症 / 基質小胞 / 細胞スフェロイド / スフェロイド / 間葉系幹細胞 … More Except Principal Investigator … More フレイル / サルコペニア / 骨代謝異常 / PAI-1 / 慢性腎臓病 Less

Mechanism of primary osteoporosis pathogenesis mediated by bone and muscle tissue-derived extracellular vesiclesPrincipal Investigator
- Principal Investigator
  
  水上優哉
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
慢性腎臓病の骨・筋への影響とPAI-1の役割について
- Principal Investigator
  
  梶博史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Mechanism of bone regeneration and bone remodeling mediated by matrix vesiclesPrincipal Investigator
- Principal Investigator
  
  Mizukami Yuya
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Elucidation of bone regenerative mechanism after mesenchymal stem cell spheroid transplantationPrincipal Investigator
- Principal Investigator
  
  Mizukami Yuya
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0906:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kindai University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Roles of Plasminogen Activator Inhibitor-1 in Heterotopic Ossification Induced by Achilles Tenotomy in Thermal Injured Mice2024
- Author(s)
  Mizukami Yuya、Kawao Naoyuki、Ohira Takashi、Hashimoto Daiki、Okada Kiyotaka、Matsuo Osamu、Kaji Hiroshi
- Journal Title
  
  Calcified Tissue International
  
  Volume: - Issue: 5 Pages: 535-549
- DOI
  10.1007/s00223-024-01193-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08642, KAKENHI-PROJECT-22K16755
[Journal Article] Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice2024
- Author(s)
  Ohira Takashi、Ino Yoko、Kawao Naoyuki、Mizukami Yuya、Okada Kiyotaka、Matsuo Osamu、Hirano Hisashi、Kimura Yayoi、Kaji Hiroshi
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: - Issue: 3 Pages: 643-658
- DOI
  10.1152/japplphysiol.00300.2023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08642, KAKENHI-PROJECT-23K10947
[Journal Article] Tmem119 is involved in bone anabolic effects of PTH through enhanced osteoblastic bone formation in mice2024
- Author(s)
  Kawao Naoyuki、Matsumura Daichi、Yamada Ayaka、Okumoto Katsumi、Ohira Takashi、Mizukami Yuya、Hashimoto Daiki、Kaji Hiroshi
- Journal Title
  
  Bone
  
  Volume: 181 Pages: 117040-117040
- DOI
  10.1016/j.bone.2024.117040
- Data Source
  KAKENHI-PROJECT-23K08642
[Journal Article] Matrix vesicles promote bone repair after a femoral bone defect in mice2023
- Author(s)
  Mizukami Yuya、Kawao Naoyuki、Takafuji Yoshimasa、Ohira Takashi、Okada Kiyotaka、Jo Jun-Ichiro、Tabata Yasuhiko、Kaji Hiroshi
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 4 Pages: e0284258-e0284258
- DOI
  10.1371/journal.pone.0284258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16755, KAKENHI-PROJECT-20K09514
[Journal Article] Renal failure suppresses muscle irisin expression, and irisin blunts cortical bone loss in mice2022
- Author(s)
  Kawao Naoyuki、Kawaguchi Miku、Ohira Takashi、Ehara Hiroki、Mizukami Yuya、Takafuji Yoshimasa、Kaji Hiroshi
- Journal Title
  
  Journal of Cachexia, Sarcopenia and Muscle
  
  Volume: 13 Issue: 1 Pages: 758-771
- DOI
  10.1002/jcsm.12892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07310, KAKENHI-PROJECT-20K23012, KAKENHI-PROJECT-20K09514
[Journal Article] Role of peripheral myelin protein 22 in chronic exercise‐induced interactions of muscle and bone in mice2022
- Author(s)
  Kawaguchi Miku、Kawao Naoyuki、Muratani Masafumi、Takafuji Yoshimasa、Ishida Masayoshi、Kinoshita Yuko、Takada Yuto、Mizukami Yuya、Ohira Takashi、Kaji Hiroshi
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: - Issue: 5 Pages: 1-11
- DOI
  10.1002/jcp.30706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07310, KAKENHI-PROJECT-19K09659, KAKENHI-PROJECT-20K23012, KAKENHI-PROJECT-20K09514, KAKENHI-PROJECT-22K09318
[Journal Article] Micro RNA 196a-5p in extracellular vesicles secreted from myoblasts suppresses osteoclast-like cell formation in mouse cells.2021
- Author(s)
  Takafuji Y, Tatsumi K, Kawao N, Okada K, Muratani M, Kaji H.
- Journal Title
  
  Calcif Tissue 108(3):364-376
  
  Volume: 108 Issue: 4 Pages: 364-376
- DOI
  10.1007/s00774-020-01201-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06863, KAKENHI-PROJECT-19K07310, KAKENHI-PROJECT-20K23012, KAKENHI-PROJECT-20K09514
[Journal Article] Influence of Angptl1 on osteoclast formation and osteoblastic phenotype in mouse cells2021
- Author(s)
  Ishida Masayoshi、Kawao Naoyuki、Mizukami Yuya、Takafuji Yoshimasa、Kaji Hiroshi
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 22 Issue: 1 Pages: 398-398
- DOI
  10.1186/s12891-021-04278-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07310, KAKENHI-PROJECT-19K09659, KAKENHI-PROJECT-20K23012, KAKENHI-PROJECT-20K09514
[Journal Article] Calcium Peroxide-Containing Polydimethylsiloxane-Based Microwells for Inhibiting Cell Death in Spheroids through Improved Oxygen Supply2021
- Author(s)
  Mizukami Yuya、Takahashi Yuki、Shimizu Kazunori、Konishi Satoshi、Takakura Yoshinobu、Nishikawa Makiya
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 10 Pages: 1458-1464
- DOI
  10.1248/bpb.b21-00269
- NAID
  130008095763
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K23012
[Journal Article] Serpinb1a suppresses osteoclast formation2021
- Author(s)
  Ishida Masayoshi、Kawao Naoyuki、Mizukami Yuya、Takafuji Yoshimasa、Kaji Hiroshi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 26 Pages: 101004-101004
- DOI
  10.1016/j.bbrep.2021.101004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07310, KAKENHI-PROJECT-19K09659, KAKENHI-PROJECT-20K23012, KAKENHI-PROJECT-20K09514
[Journal Article] Role of plasminogen activator inhibitor-1 in muscle wasting induced by a diabetic state in female mice2021
- Author(s)
  Ehara Hiroki、Takafuji Yoshimasa、Tatsumi Kohei、Okada Kiyotaka、Mizukami Yuya、Kawao Naoyuki、Matsuo Osamu、Kaji Hiroshi
- Journal Title
  
  Endocr J
  
  Volume: 68 Issue: 12 Pages: 1421-1428
- DOI
  10.1507/endocrj.EJ21-0142
- NAID
  130008136479
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07310, KAKENHI-PROJECT-20K23012, KAKENHI-PROJECT-20K09514
[Presentation] TNF- αは筋細胞への作用を介してエクソソームの骨形成作用を抑制する2023
- Author(s)
  高田雄斗、水上優哉、高藤義正、村谷匡史、大平宇志、河尾直之、岡田清孝、梶　博史
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08642
[Presentation] 非荷重による筋萎縮時における線溶系因子Plasminogen (Plg) の役割2023
- Author(s)
  大平宇志、井野洋子、河尾直之、水上優哉、岡田清孝、松尾　理、平野　久、木村弥生、梶　博史
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08642
[Presentation] 骨芽細胞由来の基質小胞は大腿骨欠損後の骨修復・再生を促進する2023
- Author(s)
  水上優哉、河尾直之、髙藤義正、大平宇志、岡田清孝、城　潤一郎、田畑泰彦、梶　博史.
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16755
[Presentation] 骨芽細胞由来の基質小胞は大腿骨欠損後の骨修復・再生を促進する2023
- Author(s)
  水上優哉、河尾直之、髙藤義正、大平宇志、岡田清孝、城　潤一郎、田畑泰彦、梶　博史
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08642
[Presentation] エラスターゼ誘発肺気腫マウスにおける慢性閉塞性肺疾患(COPD)の筋・骨への影響2023
- Author(s)
  松村大智、河尾直之、大平宇志、水上優哉、梶博史
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K08642
[Presentation] 骨芽細胞由来の基質小胞はマウス大腿骨欠損モデルにおいて骨修復・再生を促進する2022
- Author(s)
  水上優哉、高藤義正、河尾直之、大平宇志、岡田清孝、城潤一郎、田畑泰彦、梶博史
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-22K16755

1. 梶博史 (90346255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 河尾直之 (70388510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
3. 岡田清孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

mizukami yuuya 水上 優哉

Mizukami Yuya 水上 優哉

Research Projects

Research Products

Co-Researchers

Mechanism of primary osteoporosis pathogenesis mediated by bone and muscle tissue-derived extracellular vesiclesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

慢性腎臓病の骨・筋への影響とPAI-1の役割について

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of bone regeneration and bone remodeling mediated by matrix vesiclesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of bone regenerative mechanism after mesenchymal stem cell spheroid transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Roles of Plasminogen Activator Inhibitor-1 in Heterotopic Ossification Induced by Achilles Tenotomy in Thermal Injured Mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tmem119 is involved in bone anabolic effects of PTH through enhanced osteoblastic bone formation in mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Matrix vesicles promote bone repair after a femoral bone defect in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Renal failure suppresses muscle irisin expression, and irisin blunts cortical bone loss in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of peripheral myelin protein 22 in chronic exercise‐induced interactions of muscle and bone in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Micro RNA 196a-5p in extracellular vesicles secreted from myoblasts suppresses osteoclast-like cell formation in mouse cells.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Influence of Angptl1 on osteoclast formation and osteoblastic phenotype in mouse cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Calcium Peroxide-Containing Polydimethylsiloxane-Based Microwells for Inhibiting Cell Death in Spheroids through Improved Oxygen Supply2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Serpinb1a suppresses osteoclast formation2021

Author(s)

mizukami yuuya 水上優哉

Mizukami Yuya 水上優哉