SHICHI YUUKI 志智優樹

Researcher Number	20887187
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator プロテオーム解析 / 膵臓がん / EMT / ３次元培養 / スフェロイド / 糖鎖 / 癌幹細胞 / 膵癌 / シングルセル解析 / Vimentin … More / E-cadherin / SEM / スフェア / がん幹細胞 … More Except Principal Investigator 消化管 / 神経内分泌腫瘍 / EMT / 位相差顕微鏡 / 走査型電子顕微鏡 / がん幹細胞 / 消化管神経内分泌腫瘍 / 3D培養 Less

Proteomic analysis of pancreatic cancer cells in 3D culture: Search for personalized medicine and early diagnosis methodsPrincipal Investigator
- Principal Investigator
  
  志智優樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Molecular biological analysis of gastrointestinal neuroendocrine tumors and development of new therapeutic drugs
- Principal Investigator
  
  進士誠一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nippon Medical School
New therapeutic methods by variability control of pancreatic cancer cellsPrincipal Investigator
- Principal Investigator
  
  志智優樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Artificial intelligence-based analysis of time-lapse images of sphere formation and process of plate adhesion and spread of pancreatic cancer cells2023
- Author(s)
  Shichi Yuuki、Gomi Fujiya、Hasegawa Yasuko、Nonaka Keisuke、Shinji Seiichi、Takahashi Kimimasa、Ishiwata Toshiyuki
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 11 Pages: 1290753-1290753
- DOI
  10.3389/fcell.2023.1290753
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764, KAKENHI-PROJECT-22K08882
[Journal Article] Multiple cystic sphere formation from PK-8 cells in three-dimensional culture2022
- Author(s)
  Yuuki Shichi, Fujiya Gomi, Yoshibumi Ueda, Keisuke Nonaka, Fumio Hasegawa, Yasuko Hasegawa, Nae Hinata, Hisashi Yoshimura, Masami Yamamoto, Kimimasa Takahashi, Tomio Arai, Toshiyuki Ishiwata
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 32 Pages: 101339-101339
- DOI
  10.1016/j.bbrep.2022.101339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06408, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764, KAKENHI-PROJECT-22K08882
[Journal Article] Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression2022
- Author(s)
  Sasaki Norihiko、Hirano Kazumi、Shichi Yuuki、Gomi Fujiya、Yoshimura Hisashi、Matsushita Akira、Toyoda Masashi、Ishiwata Toshiyuki
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 9 Pages: 2055-2055
- DOI
  10.3390/cancers14092055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764, KAKENHI-PROJECT-22K06013, KAKENHI-PROJECT-18K14597
[Journal Article] Epithelial and Mesenchymal Features of Pancreatic Ductal Adenocarcinoma Cell Lines in Two- and Three-Dimensional Cultures2022
- Author(s)
  Shichi Yuuki、Gomi Fujiya、Sasaki Norihiko、Nonaka Keisuke、Arai Tomio、Ishiwata Toshiyuki
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 12 Issue: 5 Pages: 746-746
- DOI
  10.3390/jpm12050746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764
[Presentation] Enhanced Morphofunctional Characteristics of Pancreatic Ductal Adenocarcinoma Cell Lines in Three-Dimensional Cultures2023
- Author(s)
  Yuuki Shichi, Fujiya Gomi, Yasuko Hasegawa, Seiichi Shinji, Kimimasa Takahashi, Toshiyuki Ishiwata
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 膵癌培養細胞株におけるスフェアの形成過程および接着遊走過程のタイムラプス解析2023
- Author(s)
  志智優樹, 五味不二也, 長谷川康子, 進士誠一, 高橋公正, 石渡俊行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌細胞株の上皮間葉系形質の増強2022
- Author(s)
  石渡俊行, 志智優樹, 五味不二也, 野中敬介, 佐々木紀彦, 豊田雅士, 高橋公正, 新井冨生
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] Gp130/STAT3シグナル伝達は、長鎖ノンコーディングRNAのH19の発現を含む膵臓癌幹細胞の機能を調節する2022
- Author(s)
  佐々木紀彦, 平野和己, 志智優樹, 五味不二也, 吉村久志, 松下晃, 板倉陽子, 豊田雅士, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌培養細胞の形態学的特徴と粘液産生能の比較検討2022
- Author(s)
  志智優樹, 五味不二也, 野中敬介, 高橋公正, 新井冨生, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] FGFR4阻害剤BLU554の膵癌細胞株に対する効果2022
- Author(s)
  五味不二也, 佐々木紀彦, 志智優樹, 野中敬介, 豊田雅士, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 膵がんの上皮間葉系性質と糖鎖発現の多様性2022
- Author(s)
  志智優樹, 佐々木紀彦, 五味不二也, 野中敬介, 石渡俊行
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵がん培養細胞株の上皮間葉系形質とムチン産生能の比較検討2022
- Author(s)
  志智優樹, 五味不二也, 野中敬介, 石渡俊行
- Organizer
  第18回日本病理学会カンファレンス
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌培養細胞の上皮間葉系形質と粘液産生能の比較検討2022
- Author(s)
  志智優樹, 長谷川康子, 佐々木紀彦, 五味不二也, 野中敬介, 吉村久志, 高橋公正, 豊田雅士, 新井冨生, 石渡俊行
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 膵がん培養細胞株の老化誘導と老化細胞除去療法2022
- Author(s)
  五味不二也, 佐々木紀彦, 志智優樹, 野中敬介, 石渡俊行
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌培養細胞株の形態および機能的特徴と薬剤感受性の検討2021
- Author(s)
  志智優樹, 南風花, 佐々木紀彦, 五味不二也, 道下正貴, 塚田晃三, 豊田雅士, 高橋公正, 石渡俊行
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 2次元培養と3次元培養による膵癌培養細胞株の形態・機能変化と薬剤感受性の検討2021
- Author(s)
  石渡俊行, 南風花, 佐々木紀彦, 志智優樹, 五味不二也, 道下正貴, 豊田雅士
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K08744

1. 石渡俊行 (90203041)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. 進士誠一 (80409193)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. 佐々木紀彦 (80639063)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. YAMAMOTO Masami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHICHI YUUKI 志智 優樹

Research Projects

Research Products

Co-Researchers

Proteomic analysis of pancreatic cancer cells in 3D culture: Search for personalized medicine and early diagnosis methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular biological analysis of gastrointestinal neuroendocrine tumors and development of new therapeutic drugs

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New therapeutic methods by variability control of pancreatic cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Artificial intelligence-based analysis of time-lapse images of sphere formation and process of plate adhesion and spread of pancreatic cancer cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiple cystic sphere formation from PK-8 cells in three-dimensional culture2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epithelial and Mesenchymal Features of Pancreatic Ductal Adenocarcinoma Cell Lines in Two- and Three-Dimensional Cultures2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Enhanced Morphofunctional Characteristics of Pancreatic Ductal Adenocarcinoma Cell Lines in Three-Dimensional Cultures2023

Author(s)

Organizer

Data Source

[Presentation] 膵癌培養細胞株におけるスフェアの形成過程および接着遊走過程のタイムラプス解析2023

Author(s)

Organizer

Data Source

[Presentation] 3次元培養による膵癌細胞株の上皮間葉系形質の増強2022

Author(s)

Organizer

Data Source

[Presentation] Gp130/STAT3シグナル伝達は、長鎖ノンコーディングRNAのH19の発現を含む膵臓癌幹細胞の機能を調節する2022

Author(s)

Organizer

Data Source

[Presentation] 3次元培養による膵癌培養細胞の形態学的特徴と粘液産生能の比較検討2022

Author(s)

Organizer

Data Source

[Presentation] FGFR4阻害剤BLU554の膵癌細胞株に対する効果2022

Author(s)

Organizer

Data Source

[Presentation] 膵がんの上皮間葉系性質と糖鎖発現の多様性2022

Author(s)

Organizer

Data Source

[Presentation] 3次元培養による膵がん培養細胞株の上皮間葉系形質とムチン産生能の比較検討2022

Author(s)

Organizer

Data Source

[Presentation] 3次元培養による膵癌培養細胞の上皮間葉系形質と粘液産生能の比較検討2022

Author(s)

Organizer

Data Source

[Presentation] 膵がん培養細胞株の老化誘導と老化細胞除去療法2022

Author(s)

SHICHI YUUKI 志智優樹