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Horioka Kie  堀岡 希衣

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HORIOKA KIE  堀岡 希衣

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Researcher Number 20897730
Other IDs
Affiliation (Current) 2025: 筑波大学, 医学医療系, 特別研究員(PD)
2025: 旭川医科大学, 医学部, 客員助教
Affiliation (based on the past Project Information) *help 2025: 筑波大学, 医学医療系, 特別研究員(PD)
2024: 筑波大学, 医学医療系, その他
2023 – 2024: 旭川医科大学, 医学部, 客員助教
2021 – 2022: 国際医療福祉大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 58040:Forensics medicine-related
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
PDMV / 血小板 / 低体温症 / シバリング / 低体温 / 脾臓
Except Principal Investigator
血小板 / 肝がん
  • Research Projects

    (5 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (2 People)
  •  心筋細胞エネルギー代謝変化の視点から解明する低体温症における心筋保護機構Principal Investigator

    • Principal Investigator
      堀岡 希衣
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      University of Tsukuba
  •  肝がん関連血小板の獲得形質に介入した新たな治療法の開発

    • Principal Investigator
      田中 宏樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Asahikawa Medical College
  •  ヒト凍死体から解明する低体温症の脂質代謝機構:臨床応用に向けた法医学的アプローチPrincipal Investigator

    • Principal Investigator
      堀岡 希衣
    • Project Period (FY)
      2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research)
    • Research Institution
      University of Tsukuba
  •  血小板由来微小胞による新たな骨格筋修復機構-低体温症に伴うシバリングとの関連-Principal Investigator

    • Principal Investigator
      堀岡 希衣
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Asahikawa Medical College
  •  The true significance of platelet activation in hypothermia - physiological functional analysis and biological effects.Principal Investigator

    • Principal Investigator
      HORIOKA KIE
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      International University of Health and Welfare

All 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] A suicide case of liquid nicotine intoxication2024

    • Author(s)
      Motomura Ayumi、Inoue Hiroyuki、Ishii Namiko、Horioka Kie、Okaba Keisuke、Moue Chihiro、Ohashi Ryuto、Yajima Daisuke
    • Journal Title

      Legal Medicine

      Volume: 68 Pages: 102400-102400

    • DOI

      10.1016/j.legalmed.2024.102400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K16376
  • [Journal Article] Bioprotective role of platelet-derived microvesicles in hypothermia: Insight into the differential characteristics of peripheral and splenic platelets2023

    • Author(s)
      Horioka Kie、Tanaka Hiroki、Okaba Keisuke、Yamada Shinnosuke、Hayakawa Akira、Ishii Namiko、Motomura Ayumi、Inoue Hiroyuki、Takauji Shuhei、Isozaki Shotaro、Ogawa Katsuhiro、Yajima Daisuke、Druid Henrik、Pakanen Lasse、Porvari Katja
    • Journal Title

      Thrombosis Research

      Volume: 223 Pages: 155-167

    • DOI

      10.1016/j.thromres.2023.01.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K17411, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-22K17412, KAKENHI-PROJECT-23K16376
  • [Journal Article] Hypoxia-induced nuclear translocation of β-catenin in the healing process of frostbite2022

    • Author(s)
      Isozaki Shotaro、Tanaka Hiroki、Horioka Kie、Konishi Hiroaki、Kashima Shin、Takauji Shuhei、Fujiya Mikihiro、Druid Henrik
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

      Volume: 1868 Issue: 6 Pages: 166385-166385

    • DOI

      10.1016/j.bbadis.2022.166385

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-22K17411
  • [Journal Article] Soluble thrombomodulin ameliorates aberrant hemostasis after rewarming in a rat accidental hypothermia model2022

    • Author(s)
      Takauji Shuhei、Tanaka Hiroki、Hayakawa Mineji、Horioka Kie、Isozaki Shotaro、Konishi Hiroaki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 587 Pages: 1-8

    • DOI

      10.1016/j.bbrc.2021.11.086

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225
  • [Journal Article] Hypothermia causes platelet activation in the human spleen2021

    • Author(s)
      Horioka Kie、Tanaka Hiroki、Okaba Keisuke、Yamada Shinnosuke、Ishii Namiko、Motomura Ayumi、Inoue Hiroyuki、Alkass Kanar、Druid Henrik、Yajima Daisuke
    • Journal Title

      Thrombosis Research

      Volume: 205 Pages: 47-55

    • DOI

      10.1016/j.thromres.2021.06.023

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Journal Article] Treatment of hepatocellular carcinoma with autologous platelets encapsulating sorafenib or lenvatinib: A novel therapy exploiting tumor‐platelet interactions2021

    • Author(s)
      Tanaka Hiroki、Horioka Kie、Hasebe Takumu、Sawada Koji、Nakajima Shunsuke、Konishi Hiroaki、Isozaki Shotaro、Goto Masanori、Fujii Yumiko、Kamikokura Yuki、Ogawa Katsuhiro、Nishikawa Yuji
    • Journal Title

      International Journal of Cancer

      Volume: 150 Issue: 10 Pages: 1640-1653

    • DOI

      10.1002/ijc.33915

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-21K07167, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-22K17411
  • [Presentation] Platelet-derived microvesicles have a role in repairing muscle damage in hypothermia2023

    • Author(s)
      Kie Horioka, Hiroki Tanaka, Akira Hayakawa, Lasse Pakanen, Katja Porvari
    • Organizer
      International Society on Thrombosis and Haemostasis 2023 Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K16376
  • [Presentation] De novo protein synthesis capacity of Tumor-educated platelets2023

    • Author(s)
      Hiroki Tanaka, Kie Horioka
    • Organizer
      International Society on Thrombosis and Haemostasis 2023 Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K16376
  • [Presentation] 低体温のシバリングによる筋肉損傷に対する脾臓内血小板の役割2023

    • Author(s)
      堀岡 希衣 , 田中 宏樹 , 早川 輝 , Druid Henrik , Porvari Katja
    • Organizer
      第112回日本病理学会総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K16376
  • [Presentation] Rewarming from accidental hypothermia enhances whole blood coagulation in a mouse model2022

    • Author(s)
      Kie Horioka
    • Organizer
      International society on Thrombosis and Haemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Presentation] Rewarming from accidental hypothermia enhances whole blood clotting properties in a murine model2022

    • Author(s)
      Kie Horioka
    • Organizer
      The 21th Nordic Conference on Forensic Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Presentation] BioprotectiveRoleofPlatelet-DerivedMicrovesiclesinHypothermia:InsightsfromtheDifferential Characteristics of Peripheral and Splenic Platelets2022

    • Author(s)
      Kie Horioka
    • Organizer
      American Society of Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Presentation] 自己血小板を用いたドラッグデリバリーシステムの肝細胞癌に対するターゲティング効果2021

    • Author(s)
      田中 宏樹, 堀岡 希衣, 後藤 正憲, 人見 淳一, 藤井 裕美子, 上小倉 佑機, 孟 玲童, 小川 勝洋, 西川 祐司
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Presentation] 自己血小板を利用したドラッグデリバリーシステム 肝癌・血小板相互作用を利用した新たな治療戦略2021

    • Author(s)
      田中 宏樹, 堀岡 希衣, 後藤 正憲, 人見 淳一, 藤井 裕美子, 上小倉 佑機, 孟 玲童, 小川 勝洋, 西川 祐司
    • Organizer
      日本病理学会
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Presentation] Activation of intra-splenic platelets as a pathologic feature during deep hypothermia.2021

    • Author(s)
      Horioka K, Tanaka H, Isozaki S, Henrik D
    • Organizer
      International society on Thrombosis and Haemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Presentation] 低体温症における血小板変化と血液凝固機能異常2021

    • Author(s)
      堀岡 希衣, 田中 宏樹, 岡馬 恵介, 石井 名実子, 本村 あゆみ, 井上 博之, 矢島 大介
    • Organizer
      日本血栓止血学
    • Data Source
      KAKENHI-PROJECT-21K17328
  • [Presentation] 低体温症に対する復温療法時の活性化血小板動態と血栓形成2021

    • Author(s)
      堀岡 希衣, 田中 宏樹, 岡馬 恵介, 石井 名実子, 本村 あゆみ, 井上 博之, 矢島 大介
    • Organizer
      日本病理学会
    • Data Source
      KAKENHI-PROJECT-21K17328
  • 1.  田中 宏樹 (70596155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  磯崎 翔太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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