Sakai Mai 坂井舞

Researcher Number	20910425
Other IDs
Affiliation (Current)	2026: 東北大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 東北大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator TNF-α / うつ病 / ミクログリア / 血液脳関門 / ミトコンドリア / マウスモデル / 代謝 / 産後うつ / 行動試験 / 妊娠前ストレス / クエン酸回路 / メタボローム / 産後うつ様症状

うつ病の発症機序における血液脳関門とミクログリアの相互作用の分子基盤の解明Principal Investigator
- Principal Investigator
  
  坂井舞
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tohoku University
The Involvement of the TCA Cycle in the Pathogenesis of Postpartum DepressionPrincipal Investigator
- Principal Investigator
  
  Sakai Mai
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tohoku University

All 2025 2024 2023 2022

All Journal Article

[Journal Article] Experimenters' sex modulates anxiety-like behavior, contextual fear, and microglial oxytocin transcription in mice2025
- Author(s)
  Sakai Mai、Yu Zhiqian、Picotin Rosanne、Kasahara Tomoko、Kikuchi Yoshie、Ono Chiaki、Hino Mizuki、Kunii Yasuto、Maejima Yuko、Shimomura Kenju、Nakanishi Miharu、Abe Takaaki、Yoshii Hatsumi、Tomita Hiroaki
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 483 Pages: 115480-115480
- DOI
  10.1016/j.bbr.2025.115480
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15742, KAKENHI-PROJECT-23K06978, KAKENHI-PROJECT-23K08012
[Journal Article] Glial Markers of Suicidal Behavior in the Human BrainーA Systematic Review of Postmortem Studies2024
- Author(s)
  Yamamoto Mana、Sakai Mai、Yu Zhiqian、Nakanishi Miharu、Yoshii Hatsumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 11 Pages: 5750-5750
- DOI
  10.3390/ijms25115750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15742, KAKENHI-PROJECT-23K06978
[Journal Article] N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling2023
- Author(s)
  Sakai Mai、Yu Zhiqian、Taniguchi Masayuki、Picotin Rosanne、Oyama Nanami、Stellwagen David、Ono Chiaki、Kikuchi Yoshie、Matsui Ko、Nakanishi Miharu、Yoshii Hatsumi、Furuyashiki Tomoyuki、Abe Takaaki、Tomita Hiroaki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3798-3798
- DOI
  10.3390/ijms24043798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04812, KAKENHI-PROJECT-20K07962, KAKENHI-PROJECT-21K15268, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-22K15742
[Journal Article] Plasma metabolic disturbances during pregnancy and postpartum in women with depression2022
- Author(s)
  Z Yu, N Matsukawa, D Saigusa, I. N. Motoike, C Ono, Y Okamura, T Onuma, Y Takahashi, M Sakai, H Kudo, T Obara, K Murakami, M Shirota, S Kikuchi, N Kobayashi, Y Kikuchi, J Sugawara, N Minegishi, S Ogishima, K Kinoshita, M Yamamoto, N Yaegashi, S Kuriyama, S Koshiba, H Tomita
- Journal Title
  
  iScience
  
  Volume: 25(12) Issue: 12 Pages: 105666-105666
- DOI
  10.1016/j.isci.2022.105666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15742, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-20K07962, KAKENHI-PROJECT-21H03537

1. FURUYASHIKI Tomoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakai Mai 坂井舞

Research Projects

Research Products

Co-Researchers

うつ病の発症機序における血液脳関門とミクログリアの相互作用の分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Involvement of the TCA Cycle in the Pathogenesis of Postpartum DepressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Experimenters' sex modulates anxiety-like behavior, contextual fear, and microglial oxytocin transcription in mice2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glial Markers of Suicidal Behavior in the Human BrainーA Systematic Review of Postmortem Studies2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasma metabolic disturbances during pregnancy and postpartum in women with depression2022

Author(s)

Journal Title

DOI

Data Source

Sakai Mai 坂井 舞

Research Projects

Research Products

Co-Researchers

うつ病の発症機序における血液脳関門とミクログリアの相互作用の分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Involvement of the TCA Cycle in the Pathogenesis of Postpartum DepressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Experimenters' sex modulates anxiety-like behavior, contextual fear, and microglial oxytocin transcription in mice2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glial Markers of Suicidal Behavior in the Human BrainーA Systematic Review of Postmortem Studies2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasma metabolic disturbances during pregnancy and postpartum in women with depression2022

Author(s)

Journal Title

DOI

Data Source

Sakai Mai 坂井舞