Watanabe Hirofumi 渡辺博文

Researcher Number	20911978
Other IDs
Affiliation (Current)	2025: 新潟大学, 医歯学総合病院, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 新潟大学, 医歯学総合病院, 特任助教 2022: 新潟大学, 医歯学総合病院, 専任助教 2021: 新潟大学, 医歯学総合病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / 0903:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53040:Nephrology-related
Keywords	Principal Investigator 腎臓 / 慢性腎臓病 / 口蓋扁桃 / 糸球体腎炎 / リンパ球 / エピゲノム / IgA腎症 / バイオマーカー / 尿細管 / 急性腎障害 / 近位尿細管 … More Except Principal Investigator … More シングルセル解析 / 扁桃 / 1細胞RNA-Seq / IgA腎症 Less

免疫ネットワーク解析によるIgA腎症発症機序の解明
- Principal Investigator
  
  後藤眞
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Niigata University
Elucidation of the Pathogenic Mechanisms of IgA Nephropathy through Epigenomic AnalysisPrincipal Investigator
- Principal Investigator
  
  Watanabe Hirofumi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Niigata University
Function of ACSM2, a novel renal proximal tubular cell marker, and its clinical utilityPrincipal Investigator
- Principal Investigator
  
  Watanabe Hirofumi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0903:Organ-based internal medicine and related fields
- Research Institution
  Niigata University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Ectopic Production of Parathyroid Hormone and Production of Parathyroid Hormone-related Protein in Dedifferentiated Endometrial Carcinoma Induced Severe Hypercalcemia2025
- Author(s)
  Ogino Takeru、Watanabe Hirofumi、Yamazaki Shoko、Kurosawa Megumi、Kobayashi Akiko、Imai Naofumi、Taguchi Takahiro、Umezu Hajime、Aida Ryo、Watanabe Kazuki、Otsuka Tadashi、Kabasawa Hideyuki、Kaseda Ryohei、Yamamoto Suguru、Yoshihara Kosuke、Goto Shin、Narita Ichiei
- Journal Title
  
  Internal Medicine
  
  Volume: 64 Issue: 7 Pages: 1053-1059
- DOI
  10.2169/internalmedicine.3899-24
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09635, KAKENHI-PROJECT-22K16234
[Journal Article] Genetic and protein structure prediction analyses identify a rare pathogenic PKD1 variant causing autosomal dominant polycystic kidney disease2025
- Author(s)
  Shiiya Takamitsu、Watanabe Hirofumi、Aida Ryo、Otsuka Tadashi、Kaseda Ryohei、Yamamoto Suguru、Kaneko Yoshikatsu、Goto Shin、Narita Ichiei
- Journal Title
  
  CEN Case Reports
  
  Volume: - Issue: 4 Pages: 612-617
- DOI
  10.1007/s13730-025-00985-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16234
[Journal Article] CD38 ligation in sepsis promotes nicotinamide phosphoribosyltransferase-mediated IL-6 production in kidney stromal cells2024
- Author(s)
  Suzuki Yuya、Otsuka Tadashi、Takahashi Yusuke、Maruyama Shingo、Annenkov Alexey、Kanda Yasuhiro、Katakai Tomoya、Watanabe Hirofumi、Ohashi Riuko、Kaneko Yoshikatsu、Narita Ichiei
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: - Issue: 7 Pages: 1310-1321
- DOI
  10.1093/ndt/gfae269
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16234, KAKENHI-PROJECT-22K06998
[Journal Article] Protocol for the nationwide registry of patients with polycystic kidney disease: japanese national registry of PKD (JRP)2024
- Author(s)
  Nakatani S、Muto S, et al
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 28 Issue: 10 Pages: 1004-1015
- DOI
  10.1007/s10157-024-02509-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09484, KAKENHI-PROJECT-22K16234
[Journal Article] Nephrotic syndrome induces the upregulation of cell proliferation-related genes in tubular cells in mice2024
- Author(s)
  Suzuki Yuya、Kaseda Ryohei、Nakagawa Yusuke、Watanabe Hirofumi、Otsuka Tadashi、Yamamoto Suguru、Kaneko Yoshikatsu、Goto Shin、Matsusaka Taiji、Narita Ichiei
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 29 Issue: 4 Pages: 393-404
- DOI
  10.1007/s10157-024-02608-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16234
[Journal Article] Assessing fluid volume and determining outcomes of acute heart failure using plasma human atrial natriuretic peptide2023
- Author(s)
  Suzuki Yuya、Otsuka Tadashi、Yoshioka Yuki、Iida Tomomichi、Maruyama Shingo、Watanabe Hirofumi、Kaseda Ryohei、Yamamoto Suguru、Kaneko Yoshikatsu、Goto Shin、Aoyagi Ryuji、Narita Ichiei
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: Online ahead of print Issue: 6 Pages: 0-0
- DOI
  10.1007/s10157-023-02333-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K20917, KAKENHI-PROJECT-22K16234, KAKENHI-PROJECT-20K08628
[Journal Article] Sodium magnetic resonance imaging shows impairment of the counter-current multiplication system in diabetic mice kidney2023
- Author(s)
  Nakagawa Yusuke、Kaseda Ryohei、Suzuki Yuya、Watanabe Hirofumi、Otsuka Tadashi、Yamamoto Suguru、Kaneko Yoshikatsu、Goto Shin、Terada Yasuhiko、Haishi Tomoyuki、Sasaki Susumu、Narita Ichiei
- Journal Title
  
  Kidney360
  
  Volume: Publish Ahead of Print Issue: 5 Pages: 0-0
- DOI
  10.34067/kid.0000000000000072
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08628, KAKENHI-PROJECT-22K16234, KAKENHI-PROJECT-20K08586, KAKENHI-PROJECT-21K20917, KAKENHI-PROJECT-21H01333
[Journal Article] Defective C3d caused by <i>C3</i> p.<scp>W1034R</scp> in inherited atypical hemolytic uremic syndrome2023
- Author(s)
  Tsuchida Masafumi、Goto Shin、Watanabe Hirofumi、Goto Sawako、Yamaguchi Hiroki、Narita Ichiei
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 12 Issue: 1
- DOI
  10.1002/mgg3.2288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16234
[Journal Article] Pathogenic variants of Alport syndrome and monogenic diabetes identified by exome sequencing in a family2023
- Author(s)
  Watanabe Hirofumi、Goto Shin、Hosojima Michihiro、Kabasawa Hideyuki、Imai Naofumi、Ito Yumi、Narita Ichiei
- Journal Title
  
  Human Genome Variation
  
  Volume: 10 Issue: 1 Pages: 5-5
- DOI
  10.1038/s41439-023-00233-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16234, KAKENHI-PROJECT-21K20917
[Journal Article] Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans2021
- Author(s)
  Watanabe H, et al.
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 24
- DOI
  10.1172/jci.insight.154337
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03674, KAKENHI-PROJECT-21K20917
[Presentation] IgA腎症患者の扁桃免疫細胞の相互作用解析2025
- Author(s)
  里方一紀、後藤眞、山口浩毅、渡辺博文、椎谷貴光、成田一衞
- Organizer
  第48回IgA腎症研究会
- Data Source
  KAKENHI-PROJECT-24K11383
[Presentation] 高齢CKD患者におけるRA系阻害薬への期待と懸念2024
- Author(s)
  渡辺博文
- Organizer
  第67回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16234
[Presentation] シングルセルRNA-seqによる腎臓病メカニズム解明の可能性2024
- Author(s)
  渡辺博文
- Organizer
  第54回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16234
[Presentation] 腎硬化症における輸入細動脈肥厚と臨床所見・降圧薬の関連に関する研究2024
- Author(s)
  渡辺博文, 忰田亮平，山本卓，後藤眞，成田一衛
- Organizer
  第67回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16234
[Presentation] 血中濃度測定で治療効果が証明された，血液透析により急性カフェイン中毒を救命し得た一例2023
- Author(s)
  渡辺博文，大塚忠司，忰田亮平，山本卓，後藤眞，成田一衛
- Organizer
  第68回日本透析医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16234
[Presentation] 腎レニン細胞の核メカノトランスダクション機構による恒常性維持2023
- Author(s)
  渡辺博文
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16234
[Presentation] エクソーム解析により新規変異を同定した Alport 症候群と家族性若年糖尿病の一家系2022
- Author(s)
  渡辺博文，後藤眞，細島康宏，成田一衛
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K20917
[Presentation] Renin Cell Baroreceptor, a Nuclear Mechanotransducer Central for Homeostasis2022
- Author(s)
  渡辺博文
- Organizer
  第65回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K20917
[Presentation] Renin Cell Baroreceptor, a Nuclear Mechanotransducer Central for Homeostasis2022
- Author(s)
  渡辺博文
- Organizer
  第65回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16234
[Presentation] エクソーム解析により新規変異を同定した Alport 症候群と家族性若年糖尿病の一家系2022
- Author(s)
  渡辺博文，後藤眞，細島康宏，成田一衛
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K16234

1. 後藤眞 (00463969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. MUTO Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. YOSHIHARA Kousuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 成田一衛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 山本卓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 後藤祐児

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中岡博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Hirofumi 渡辺 博文

Research Projects

Research Products

Co-Researchers

免疫ネットワーク解析によるIgA腎症発症機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the Pathogenic Mechanisms of IgA Nephropathy through Epigenomic AnalysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Function of ACSM2, a novel renal proximal tubular cell marker, and its clinical utilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Ectopic Production of Parathyroid Hormone and Production of Parathyroid Hormone-related Protein in Dedifferentiated Endometrial Carcinoma Induced Severe Hypercalcemia2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic and protein structure prediction analyses identify a rare pathogenic PKD1 variant causing autosomal dominant polycystic kidney disease2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD38 ligation in sepsis promotes nicotinamide phosphoribosyltransferase-mediated IL-6 production in kidney stromal cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protocol for the nationwide registry of patients with polycystic kidney disease: japanese national registry of PKD (JRP)2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nephrotic syndrome induces the upregulation of cell proliferation-related genes in tubular cells in mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Assessing fluid volume and determining outcomes of acute heart failure using plasma human atrial natriuretic peptide2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sodium magnetic resonance imaging shows impairment of the counter-current multiplication system in diabetic mice kidney2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Defective C3d caused by <i>C3</i> p.<scp>W1034R</scp> in inherited atypical hemolytic uremic syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathogenic variants of Alport syndrome and monogenic diabetes identified by exome sequencing in a family2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] IgA腎症患者の扁桃免疫細胞の相互作用解析2025

Author(s)

Organizer

Data Source

[Presentation] 高齢CKD患者におけるRA系阻害薬への期待と懸念2024

Author(s)

Organizer

Data Source

Watanabe Hirofumi 渡辺博文