Kasai Yutaka 笠井優

… Alternative Names

笠井優カサイユタカ

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Researcher Number	20938930
Other IDs
Affiliation (Current)	2026: 日本医科大学, 先端医学研究所, プロジェクト助教
Affiliation (based on the past Project Information) *help	2026: 日本医科大学, 先端医学研究所, プロジェクト助教 2024: 日本医科大学, 先端医学研究所, プロジェクト助教 2023: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 細胞接着 / 表面プラズモン共鳴 / 分子間相互作用 / 細胞接着分子 / がん転移 Except Principal Investigator がん転移 / 免疫グロブリンスーパーファミリータンパク質 / 分子標的薬耐性 / ゲノム網羅的多型解析 / NK細胞 … More / 免疫チェックポイント / 抗体・薬物複合体 / 小細胞肺がん / 分子間結合 / IgSF Less

合成細胞接着分子を用いたがん転移制御機構の解明Principal Investigator
- Principal Investigator
  
  笠井優
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nippon Medical School
細胞接着分子群の特性と体質の解明に基づくがんの新規診断、治療法の確立と意義の解明
- Principal Investigator
  
  村上善則
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nippon Medical School
表面プラズモン共鳴イメージング法を用いたがん転移促進接着分子の探索Principal Investigator
- Principal Investigator
  
  笠井優
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nippon Medical School
  The University of Tokyo

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] Multiple functions of Cell adhesion molecule 1 (CADM1) and its role in the pathogenesis of cancer and other diseases.2025
- Author(s)
  Murakami Y, Kasai Y, Masuda T, Ichikawa H, Ito T.
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02319
[Journal Article] PKR associates with 4.1R to promote anchorage-independent growth of hepatocellular carcinoma and lead to poor prognosis2024
- Author(s)
  Okujima Yusuke、Watanabe Takao、Ito Takeshi、Inoue Yasumichi、Kasai Yutaka、Imai Yusuke、Nakamura Yoshiko、Koizumi Mitsuhito、Yoshida Osamu、Tokumoto Yoshio、Hirooka Masashi、Abe Masanori、Kawakami Ryosuke、Saitou Takashi、Imamura Takeshi、Murakami Yoshinori、Hiasa Yoichi
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 27768-27768
- DOI
  10.1038/s41598-024-75142-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15012, KAKENHI-PROJECT-24K02197, KAKENHI-PROJECT-24K02319, KAKENHI-PROJECT-24K11072, KAKENHI-PROJECT-24K11113, KAKENHI-PROJECT-24K15178
[Journal Article] <scp>IGSF3</scp> is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium2024
- Author(s)
  Guo Yue、Kasai Yutaka、Tanaka Yuto、Ohashi‐Kumagai Yuki、Sakamoto Takeharu、Ito Takeshi、Murakami Yoshinori
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 1936-1947
- DOI
  10.1111/cas.16166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14558, KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-24K02319
[Presentation] CADM1 is a potential target for diagnosis and treatment of small cell lung cancer.2025
- Author(s)
  Ito T, Kasai Y, Kawahara M, Funaki T, Sakamoto T, Tanaka G, Nagase T, Katayama R, Murakami Y.
- Organizer
  The 13th AACR-JCA Joint Conference: From Cancer Discovery Science to Therapeutic Innovation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02319
[Presentation] VSIG4に対するNK細胞上の抑制性受容体Siglec-7の同定2024
- Author(s)
  笠井優、小宮みこ、伊東剛、村上善則
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K14558
[Presentation] SIGLEC7はVSIG４に対するNK細胞上の免疫チェックポイント受容体である2024
- Author(s)
  笠井優、東侑生、水澤舞、三戸部耀太、坪井裕見、小宮みこ、伊東剛、村上善則
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14558
[Presentation] 網羅的相互作用スクリーニングによるVSIG4に対するNK細胞上の抑制性受容体Siglec-7の同定2024
- Author(s)
  笠井優、小宮みこ、伊東剛、村上善則
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-24K02319
[Presentation] SIGLEC7はVSIG4に対するNK細胞上の免疫チェックポイント受容体である。2024
- Author(s)
  笠井優、東侑生、水澤舞、三戸部耀太、坪井裕見、小宮みこ、伊東剛、村上善則。
- Organizer
  第47回日本分子生物学会年会（シンポジウム）
- Data Source
  KAKENHI-PROJECT-24K02319
[Presentation] Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium2023
- Author(s)
  Yutaka Kasai, Takeharu Sakamoto, Takeshi Ito, Yoshinori Murakami
- Organizer
  25th International Charles Heidelberger Symposium on Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14558
[Presentation] 細胞接着分子CADM1のトランス結合における糖鎖修飾の役割2023
- Author(s)
  笠井優、伊東剛、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K14558
[Presentation] 細胞接着分子CADM1はT細胞リンパ腫の臓器浸潤を促進する2023
- Author(s)
  笠井優、坂本毅治、伊東剛、村上善則
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14558
[Presentation] Siglec-7はVSIG4に対する抑制性受容体であり、NK細胞の免疫チェックポイントを制御する2023
- Author(s)
  水澤舞、坪井裕見、笠井優、伊東剛、村上善則
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K14558

1. 村上善則 (30182108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 松原大祐 (80415554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 今井祐輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kasai Yutaka 笠井 優

笠井 優 カサイ ユタカ

Research Projects

Research Products

Co-Researchers

合成細胞接着分子を用いたがん転移制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞接着分子群の特性と体質の解明に基づくがんの新規診断、治療法の確立と意義の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

表面プラズモン共鳴イメージング法を用いたがん転移促進接着分子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Multiple functions of Cell adhesion molecule 1 (CADM1) and its role in the pathogenesis of cancer and other diseases.2025

Author(s)

Journal Title

Data Source

[Journal Article] PKR associates with 4.1R to promote anchorage-independent growth of hepatocellular carcinoma and lead to poor prognosis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <scp>IGSF3</scp> is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium2024

Author(s)

Journal Title

DOI

Data Source

[Presentation] CADM1 is a potential target for diagnosis and treatment of small cell lung cancer.2025

Author(s)

Organizer

Data Source

[Presentation] VSIG4に対するNK細胞上の抑制性受容体Siglec-7の同定2024

Author(s)

Organizer

Data Source

[Presentation] SIGLEC7はVSIG４に対するNK細胞上の免疫チェックポイント受容体である2024

Author(s)

Organizer

Data Source

[Presentation] 網羅的相互作用スクリーニングによるVSIG4に対するNK細胞上の抑制性受容体Siglec-7の同定2024

Author(s)

Organizer

Data Source

[Presentation] SIGLEC7はVSIG4に対するNK細胞上の免疫チェックポイント受容体である。2024

Author(s)

Organizer

Data Source

[Presentation] Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium2023

Author(s)

Organizer

Data Source

[Presentation] 細胞接着分子CADM1のトランス結合における糖鎖修飾の役割2023

Author(s)

Organizer

Data Source

[Presentation] 細胞接着分子CADM1はT細胞リンパ腫の臓器浸潤を促進する2023

Author(s)

Organizer

Data Source

[Presentation] Siglec-7はVSIG4に対する抑制性受容体であり、NK細胞の免疫チェックポイントを制御する2023

Author(s)

Organizer

Data Source

Kasai Yutaka 笠井優

笠井優カサイユタカ