Maenosono Ryoichi 前之園良一

Researcher Number	20976831
Affiliation (Current)	2026: 大阪医科薬科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 大阪医科薬科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / 0803:Pathology, infection/immunology, and related fields Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator 三次リンパ様構造 / 濾胞ヘルパーT細胞 / 尿路上皮癌 / 泌尿器腫瘍免疫 / 性差 / estradiol / 女性ホルモン / 臓器移植 / 移植免疫 Except Principal Investigator BNCT / BOAI / 浸潤癌 / 膀胱温存

Investigation of the relation between tertiary lymphoid structures and T follicular helper cells in urotherial carcinomaPrincipal Investigator
- Principal Investigator
  
  前之園良一
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Investigation of the relation between age-related estradiol fluctuation and pro-/anti-inflammatory effects in transplant immune response.Principal Investigator
- Principal Investigator
  
  Maenosono Ryoichi
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka Medical and Pharmaceutical University
Therapeutic effect of boron neutron supplementation therapy with PDL1 antibody for advanced bladder cancer (including metastasis)
- Principal Investigator
  
  東治人
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka Medical and Pharmaceutical University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Spatial Architecture of the Tumor Microenvironment in Immune Checkpoint Inhibitor?Induced Hyper Progressive Bladder Cancer2025
- Author(s)
  Maenosono Ryoichi、Nishimura Kazuki、Hirosuna Kensuke、Sakamoto Moritoshi、Ajiro Masahiko、Komura Kazumasa、Azuma Haruhito、Yoshimi Akihide
- Journal Title
  
  Journal of Cellular Immunology
  
  Volume: 7 Issue: 1 Pages: 32-36
- DOI
  10.33696/immunology.7.220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K19661
[Journal Article] Transplanting old organs promotes senescence in young recipients2024
- Author(s)
  Iske J、Roesel MJ.、Martin F、Schroeter A、Matsunaga T、Maenosono R、Tripathi U、Xiao Y、Nian Y、Caldarone BJ.、Vondran FWR.、Sage PT、Azuma H、Abdi R、Elkhal A、Pirtskhalava T、Tchkonia T、Kirkland JL、Zhou H、Tullius SG
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 24 Issue: 3 Pages: 391-405
- DOI
  10.1016/j.ajt.2023.10.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19490
[Journal Article] Usefulness of Dietary Salt Restriction in Kidney Transplant Recipients: Analysis of Blood Pressure Levels Depending on the Differences in the Levels of Salt Intake2023
- Author(s)
  Hirano H,Fujiwara Y, Maenosono R,Minami K,Uehara H,Okabe T, Nakamori K,Nomi H,Komura K, Inamoto T,Azuma H.
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 55 Issue: 4 Pages: 841-4
- DOI
  10.1016/j.transproceed.2023.03.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Tertiary lymphoid structure and neutrophil?lymphocyte ratio coordinately predict outcome of pembrolizumab2023
- Author(s)
  Komura K,Tokushige S, Ishida M, Hirosuna K,Yamazaki S,Nishimura K,Ajiro M,Ohno T,Nakamori K,Kinoshita S,Tsujino T, Maenosono R,Yoshikawa Y, Takai T, Tsutsumi T,Taniguchi K,Tanaka T,Takahara K, Inamoto T,Hirose Y, Ono F,Shiraishi Y,Yoshimi A,Azuma H.
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 12 Pages: 4622-31
- DOI
  10.1111/cas.15976
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-21H04828, KAKENHI-PROJECT-23K21471, KAKENHI-PROJECT-23K27379
[Journal Article] Nephron-sparing ureteroscopic surgery vs. radical nephroureterectomy: comparable survival-outcomes in upper tract urothelial carcinoma2023
- Author(s)
  Tsujino T,Komura K,Inamoto T,Maenosono R,Hashimoto T, Adachi T, Hirasawa Y,Tokushige S,Ohno T,Yamazaki S,Fukushima T,Nakamura K,Yano Y,Nishimura K,Kinoshita S,Nakamori K,Tsutsumi T,Matsunaga T,Yoshikawa Y,Uchimoto T,Takai T,Minami K,Uehara H,Hirano H,Nomi H,Takaraha K,Ohno Y,Azuma H.
- Journal Title
  
  World Journal of Urology
  
  Volume: 41 Issue: 12 Pages: 3585-91
- DOI
  10.1007/s00345-023-04687-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-22K09512, KAKENHI-PROJECT-19K09702
[Journal Article] The Impact of FGFR3 Alterations on the Tumor Microenvironment and the Efficacy of Immune Checkpoint Inhibitors in Bladder Cancer2023
- Author(s)
  Komura K, Hirosuna K, Tokushige S, Nishimura K, Ishida M, Hayashi T, Ura A, Ohno T, Yamazaki S, Nakamori K, Kinoshita S, Tsujino T, Maenosono R, Ajiro M, Yoshikawa Y, Takai T, Tsutsumi T, Taniguchi K, Tanaka T, Takahara K, Konuma T, Inamoto T, Hirose Y, Ono F, Shiraishi Y, Yoshimi A#, Azuma H.
- Journal Title
  
  Molecular Cancer
  
  Volume: 22 Issue: 1 Pages: 185-185
- DOI
  10.1186/s12943-023-01897-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17431, KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-21H04828, KAKENHI-PROJECT-23K21471, KAKENHI-PROJECT-23K27379
[Journal Article] Real-world survival outcome comparing abiraterone acetate plus prednisone and enzalutamide for nonmetastatic castration‐resistant prostate cancer2023
- Author(s)
  Tsujino Takuya, Tokushige Satoshi, Komura Kazumasa, et al
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 19 Pages: 19414-19422
- DOI
  10.1002/cam4.6536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14606, KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-22K09512, KAKENHI-PROJECT-22K20806
[Journal Article] Sex difference and immunosenescence affect transplantation outcomes2023
- Author(s)
  Maenosono R.
- Journal Title
  
  Frontiers in Transplantation
  
  Volume: 2
- DOI
  10.3389/frtra.2023.1235740
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19490
[Journal Article] Unplanned hemodialysis initiation and low geriatric nutritional risk index scores are associated with end-stage renal disease outcomes.2022
- Author(s)
  Maenosono R,Fukushima T, Kobayashi D, Matsunaga T, Yano Y, Taniguchi S, Fujiwara Y, Komura K, Uehara H, Kagitani M, Hirano H, Inamoto T, Nomi H, Azuma H.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 11101-11101
- DOI
  10.1038/s41598-022-14123-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents2021
- Author(s)
  Komura Kazumasa、Inamoto Teruo、Tsujino Takuya、Matsui Yusuke et al.
- Journal Title
  
  Oncogene
  
  Volume: 40 Issue: 43 Pages: 6210-6222
- DOI
  10.1038/s41388-021-02021-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18151, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-23K20389
[Journal Article] Hemodialysis Initiation in Oldest-Old Patients: A Case Series.2021
- Author(s)
  Maenosono R,Matsunaga T,Yoshikawa Y,Nishimura K,Onaka H, Komura K, Uehara H,Azuma H.
- Journal Title
  
  Case Rep Nephrol Dial
  
  Volume: 11 Issue: 3 Pages: 286-91
- DOI
  10.1159/000518706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Taurodeoxycholic acid and valine reverse obesity-associated augmented alloimmune responses and prolong allograft survival.2021
- Author(s)
  Quante M, Iske J, Uehara H, Minami K, Nian Y, Maenosono R, Matsunaga T, Liu Y, Azuma H, Perkins D, Alegre ML, Zhou H, Elkhal A, Tullius SG.
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 22 Issue: 2 Pages: 402-13
- DOI
  10.1111/ajt.16856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09702, KAKENHI-PROJECT-21K09386
[Journal Article] Recipient sex and estradiol levels affect transplant outcomes in an age-specific fashion.2021
- Author(s)
  Maenosono R, Nian Y, Iske J,Minami K, Rommel T, Martin F, Abdi R,Azuma H, Rosner BA, Zhou H, Milford E, Elkhal A, Tullius SG.
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 21(10) Issue: 10 Pages: 3239-55
- DOI
  10.1111/ajt.16611
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Risk Classification for Overall Survival by the Neutrophil-Lymphocyte Ratio and the Number of Metastatic Sites in Patients Treated with Pembrolizumab-A Multicenter Collaborative Study in Japan.2021
- Author(s)
  Uchimoto T,Komura K,Fukuokaya W, Kimura T,Takahashi K, Yano Y, Nishimura K Nakamori K,Fujiwara Y,Matsunaga T,Tsutsumi T,Tsujino T, Maenosono R,Yoshikawa Y,Taniguchi K,Tanaka T,Uehara H, Hirano H,Nomi H,Takahara K,Inamoto T,Egawa S, Azuma H.
- Journal Title
  
  Cancers
  
  Volume: 13(14)3554 Issue: 14 Pages: 1-10
- DOI
  10.3390/cancers13143554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] NECTIN4 modulates tumor microenvironment and shapes the response to immune checkpoint blockade in bladder cancer.2024
- Author(s)
  Maenosono R,Nishimura K, Hirosuna K, Komura K, Owari T, Tsujino T, Kudo R, Kawachi A, Kurikawa M, Yamauchi H, Mukohyama J, Muto T, Ishida M, Zenkoh J, Ajiro M, Suzuki Y, Nishikawa H, Koyama S, Azuma H, Yoshimi A.
- Organizer
  第83回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] The influence of follicular helper T cells and tertiary lymphoid structure in the urothelial cell carcinoma patients.2024
- Author(s)
  Maenosono R, Nishimura K, Tsujino T, Komura K, Uehara H, Hirano H, Nomi H, Inamoto T, Yoshimi A, Azuma H
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-24K19661
[Presentation] The influence of follicular helper T cells and tertiary lymphoid structure in the urothelial cell carcinoma patients.2024
- Author(s)
  Maenosono R, Nishimura K, Tsujino T, Komura K, Uehara H, Hirano H, Nomi H, Inamoto T, Yoshimi A, Azuma H
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K19490
[Presentation] The influence of follicular helper T cells and tertiary lymphoid structure in the urothelial cell carcinoma patients.2024
- Author(s)
  Maenosono R,Nishimura K, Tsujino T, Komura K, Uehara H, Hirano H, Nomi H, Inamoto T, Yoshimi A, Azuma H.
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] A multi-omics analysis revealed NECTIN4 as a potential predictive marker of precision therapy in bladder cancer.2024
- Author(s)
  Maenosono R, Nishimura K, Hirosuna K, Komura K, Owari T, Tsujino T, Kudo R, Kawachi A, Uehara H, Inamoto T, Muto T, Ishida M, Ajiro M, Nishikawa H, Koyama S, Azuma H, Yoshimi A
- Organizer
  FY2023 Young Researchers Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-24K19661
[Presentation] Crucial roles of NECTIN4 in driving bladder cancer progression, microenvironment remodeling, and immunotherapy outcome.2024
- Author(s)
  Nishimura K,Maenosono R, Owari T,Hirosuna K, Komura K, Tsujino T, Muto T,Ishida M,Zenkoh J,Ajiro M, Suzuki Y, Nishikawa H, Koyama S,Azuma H,Yoshim A.
- Organizer
  第62回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] NECTIN4 modulates tumor microenvironment and shapes the response to immune checkpoint blockade in bladder cancer.2024
- Author(s)
  Maenosono R,Nishimura K, Hirosuna K, Komura K, Owari T, Kawachi A, Mukohyama J, Ishida M, Zenkoh J, Ajiro M, Suzuki Y, Nishikawa H, Koyama S, Azuma H, Yoshimi A.
- Organizer
  第28回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] The association between outcome and malnutrition score in hemodialysis associated renal cancer patients.2023
- Author(s)
  Maenosono R,Okabe T,Shinmyo T, Hanamori T, Goji K,Tsujino T, Uehara H,Komura K,Hirano H, Nomi H,Inamoto T,Azuma H.
- Organizer
  AOS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 限局性膀胱癌に対する膀胱温存療法の年齢層別解析.2023
- Author(s)
  稲元輝生、辻野拓也、前之園良一、西村一希、中村公、大野貴也、髙井朋聡、小村和正、上原博史、平野一、能見勇人、東治人.
- Organizer
  第73回日本泌尿器科学会中部総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Importance of management of lifestyle-related diseases after kidney donation to living donors.2023
- Author(s)
  Hirano H,Fujiwara Y, Okabe T,Nakamori K, Maenosono R, Minami K,Uehara H, Nomi H,Komura K,Inamoto, Azuma H.
- Organizer
  CAST2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Occurrence of Malignant Tumors in Post-Renal Transplant Patients at Our Hospital2022
- Author(s)
  Minami K,Hirano H, Uehara H,Komura　K, Maenosono R,Fujiwara Y,Okabe T, Nakamori K,Inamoto T,Nomi H, Azuma H.
- Organizer
  2022　TSS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 上部尿路腫瘍に対する臓器温存の経験と生検病理組織の解析2022
- Author(s)
  稲元輝生、中森啓太、徳永雄希、前之園　良一、辻野拓也、南　幸一郎、小村和正、上原博史、能見勇人、東　治人.
- Organizer
  第43回日本レーザー医学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Cost Effectiveness of Kidney Transplantation in High-Immunological Risk Patients in a Japan Cohort2022
- Author(s)
  Maenosono　R,Unagami k, Oki R, Fujiwara Y, Yagisawa T,Kanzawa T,Hirai T,Omoto K,Azuma H,Ishida H, Takagi T.
- Organizer
  Transplantation Science Symposium(TSS) Asian Regional Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 高感作の腎移植候補患者での治療にかかる医療費の検討2022
- Author(s)
  前之園　良一、海上耕平、大木　里花子、藤原裕也、八木澤　隆史、神澤太一、尾本和也、東　治人、石田英樹、高木敏男.
- Organizer
  第72回日本泌尿器科学会中部総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] HoとNdによるUTUC治療と成績2022
- Author(s)
  稲元輝生、中森啓太、徳永雄希、前之園　良一、辻野拓也、南　幸一郎、小村和正、上原博史、能見勇人、東　治人.
- Organizer
  第36回日本泌尿器内視鏡・ロボティクス学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Recipient sex hormone affect transplant outcomes in an age-specific fashion2022
- Author(s)
  Maenosono　R,Nian Y, Iske J,Azuma H,Tullius S.G.
- Organizer
  Transplantation Science Symposium(TSS) Asian Regional Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 当院における腎移植後患者における悪性腫瘍発生について2022
- Author(s)
  南　幸一郎,岡部知太,前之園良一,藤原裕也,中森啓太,上原博史,平野一,能見勇人,東治人 .
- Organizer
  第58回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Usefulness Of Dietary Salt Restriction In Kidney Transplant Recipients: Analysis Of Blood Pressure Levels Depending On The Differences In The Levels Of Salt Intake2022
- Author(s)
  Hirano H,Fujiwara　Y, Maenosono　R,Minami　K,Uehara　H,Okabe　T,Nakamori　K, Nomi　H,Komura　K,Inamoto　T, Azuma　H.
- Organizer
  2022　TSS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 当院での生体腎移植後患者における、新型コロナウイルスワクチンの有用性2022
- Author(s)
  岡部知太,平野　一, 前之園　良一,中森啓太, 藤原裕也,南　幸一郎, 上原博史, 能見勇人,稲元輝生, 東　治人.
- Organizer
  第58回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-21K09386

1. 東治人 (40231914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
2. 鈴木実 (00319724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 小野公二 (90122407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
4. 稲元輝生 (20330087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. 辻野拓也 (60937407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. 小村和正 (10789853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
7. 吉川勇希 (51007505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 上原博史 (20822555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
9. 松井佑介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 吉見昭秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maenosono Ryoichi 前之園 良一

Research Projects

Research Products

Co-Researchers

Investigation of the relation between tertiary lymphoid structures and T follicular helper cells in urotherial carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the relation between age-related estradiol fluctuation and pro-/anti-inflammatory effects in transplant immune response.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic effect of boron neutron supplementation therapy with PDL1 antibody for advanced bladder cancer (including metastasis)

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Spatial Architecture of the Tumor Microenvironment in Immune Checkpoint Inhibitor?Induced Hyper Progressive Bladder Cancer2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transplanting old organs promotes senescence in young recipients2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Usefulness of Dietary Salt Restriction in Kidney Transplant Recipients: Analysis of Blood Pressure Levels Depending on the Differences in the Levels of Salt Intake2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tertiary lymphoid structure and neutrophil?lymphocyte ratio coordinately predict outcome of pembrolizumab2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nephron-sparing ureteroscopic surgery vs. radical nephroureterectomy: comparable survival-outcomes in upper tract urothelial carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Impact of FGFR3 Alterations on the Tumor Microenvironment and the Efficacy of Immune Checkpoint Inhibitors in Bladder Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Real-world survival outcome comparing abiraterone acetate plus prednisone and enzalutamide for nonmetastatic castration‐resistant prostate cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sex difference and immunosenescence affect transplantation outcomes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unplanned hemodialysis initiation and low geriatric nutritional risk index scores are associated with end-stage renal disease outcomes.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hemodialysis Initiation in Oldest-Old Patients: A Case Series.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Taurodeoxycholic acid and valine reverse obesity-associated augmented alloimmune responses and prolong allograft survival.2021

Author(s)

Journal Title

Maenosono Ryoichi 前之園良一