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Tsukamoto Tomohito  塚本 智仁

ORCIDConnect your ORCID iD *help
Researcher Number 20977342
Other IDs
Affiliation (based on the past Project Information) *help 2023 – 2024: 大阪大学, 大学院薬学研究科, 招へい教員
Review Section/Research Field
Principal Investigator
0801:Pharmaceutical sciences and related fields / Basic Section 90120:Biomaterials-related
Keywords
Principal Investigator
核局在化シグナル / 免疫 / CRISPR / アデノウイルスベクター / Cas12a / 免疫応答 / ゲノム編集 / Cas9
  • Research Projects

    (2 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (1 People)
  •  強力なCas9阻害効果を持つ人工アミノ酸導入型・抗CRISPRタンパク質の開発Principal Investigator

    • Principal Investigator
      塚本 智仁
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Osaka University
  •  Development of novel technology to suppress immune response to Cas9Principal Investigator

    • Principal Investigator
      Tsukamoto Tomohito
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      Osaka University

All 2025 2024 2023

All Journal Article Presentation

  • [Journal Article] Evaluation of the correlation between nuclear localization levels and genome editing efficiencies of Cas12a fused with nuclear localization signals2025

    • Author(s)
      Tsukamoto Tomohito、Mizuta Haruna、Sakai Eiko、Sakurai Fuminori、Mizuguchi Hiroyuki
    • Journal Title

      Journal of Pharmaceutical Sciences

      Volume: 114 Issue: 2 Pages: 841-848

    • DOI

      10.1016/j.xphs.2024.10.029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23H00552, KAKENHI-PROJECT-23K19427
  • [Presentation] 遺伝子治療への応用を目指したCRISPR-Cas12aシステム搭載アデノウイルスベクターの開発2024

    • Author(s)
      塚本智仁、中川晋作、水口裕之
    • Organizer
      日本薬学会第144年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K19427
  • [Presentation] 細胞質におけるLbCas12aの分解を利用した新たなゲノム編集ツールの開発2024

    • Author(s)
      塚本智仁、水田陽菜、小阪田悠生、好光恵梨子、酒井英子、櫻井文教、中川晋作、水口裕之
    • Organizer
      日本ゲノム編集学会 第9回大会
    • Data Source
      KAKENHI-PROJECT-23K19427
  • [Presentation] Cas12aの細胞内局在がタンパク質安定性とゲノム編集効率に及ぼす影響2023

    • Author(s)
      塚本智仁、水田陽菜、酒井英子、櫻井文教、中川晋作、水口裕之
    • Organizer
      第73回 日本薬学会関西支部総会・大会
    • Data Source
      KAKENHI-PROJECT-23K19427
  • 1.  水口 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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