Kurisawa Naoaki 栗澤尚瑛

Researcher Number	20980618
Affiliation (Current)	2026: 慶應義塾大学, 理工学部(矢上), 助教
Affiliation (based on the past Project Information) *help	2023 – 2025: 慶應義塾大学, 理工学部(矢上), 助教
Review Section/Research Field	Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / 0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields Except Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
Keywords	Principal Investigator 分子系統解析 / 新規天然物 / ケミカルバイオロジー / 構造活性相関 / 海洋天然物 / カルシウムポンプ / SERCA / イエゾシド Except Principal Investigator 構造活性相関 / カルシウムポンプ阻害剤 … More / 抗マラリア薬リード化合物 / 抗マラリア活性 / イエゾシド / カルシウムポンプ / マラリア原虫 / 海洋シアノバクテリア Less

Exploration of novel natural products using molecular phylogeneticsPrincipal Investigator
- Principal Investigator
  
  栗澤尚瑛
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Keio University
海洋産カルシウムポンプ阻害剤に基づく抗マラリア薬リード化合物の創製
- Principal Investigator
  
  末永聖武
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Keio University
Elucidation of a novel mode of action of iezoside based on the structure-activity relationshipPrincipal Investigator
- Principal Investigator
  
  Kurisawa Naoaki
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields
- Research Institution
  Keio University

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] Sealgamide: An Antitrypanosomal Lipopeptide Isolated from a Marine Okeania sp. Cyanobacterium2025
- Author(s)
  Wakai Kazuki、Kurisawa Naoaki、Umeda Kairi、Jeelani Ghulam、Agusta Adnan Luthfi、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  Journal of Natural Products
  
  Volume: - Issue: 4 Pages: 1048-1056
- DOI
  10.1021/acs.jnatprod.5c00141
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K10185
[Journal Article] Isolation and Total Synthesis of Ukabamide, an Antitrypanosomal Lipopeptide from a Marine Moorena sp. Cyanobacterium2025
- Author(s)
  Hagihara Masahiro、Kurisawa Naoaki、Iwasaki Arihiro、Taguchi Raimu、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  Organic Letters
  
  Volume: 27 Issue: 5 Pages: 1261-1264
- DOI
  10.1021/acs.orglett.4c04832
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K01639, KAKENHI-PROJECT-24K08620, KAKENHI-PROJECT-24K10185, KAKENHI-PROJECT-24KJ1289
[Journal Article] Isolation and structure determination of a new analog of polycavernosides from marine Okeania sp. cyanobacterium2024
- Author(s)
 Umeda Kairi、Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake、Iwasaki Arihiro
- Journal Title
 
 Beilstein Journal of Organic Chemistry
 
 Volume: 20 Pages: 645-652
- DOI
 10.3762/bjoc.20.57
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-21KK0099, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870
[Journal Article] Structure-Activity Relationship Studies on Iezoside, a Highly Potent Ca2+ ATPase Inhibitor2024
- Author(s)
  Naoaki Kurisawa, Kazuya Teranuma, Akari Noto, Arihiro Iwasaki, Yoshiki Kabashima, Rie Nakajima, Chikashi Toyoshima, and Kiyotake Suenaga
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 97 Issue: 7 Pages: 1-7
- DOI
  10.1093/bulcsj/uoae070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K01639
[Journal Article] Wajeepeptin, a Cytotoxic and Antitrypanosomal Cyclic Depsipeptide from a Marine Moorena sp. Cyanobacterium2024
- Author(s)
  Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Agusta Adnan Luthfi、Suenaga Kiyotake、Iwasaki Arihiro
- Journal Title
  
  Journal of Natural Products
  
  Volume: 87 Issue: 7 Pages: 1838-1843
- DOI
  10.1021/acs.jnatprod.4c00499
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K01639, KAKENHI-PROJECT-24K10185
[Journal Article] The Bioorganic Study of Iezoside: A Novel SERCA Inhibitor from the Marine Cyanobacterium2024
- Author(s)
  Kurisawa N.; Iwasaki A.; Suenaga K
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 82 Issue: 11 Pages: 1107-1116
- DOI
  10.5059/yukigoseikyokaishi.82.1107
- ISSN
  0037-9980, 1883-6526
- Year and Date
  2024-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K01639
[Journal Article] Total synthesis of acetylene-containing lipopeptides odookeanynes A and B2023
- Author(s)
  Lo Yung-Han、Umeda Kairi、Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 130 Pages: 154763-154763
- DOI
  10.1016/j.tetlet.2023.154763
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870
[Journal Article] Isolation and Structure Determination of Akunolides, Macrolide Glycosides from a Marine Okeania sp. Cyanobacterium2023
- Author(s)
 Umeda Kairi、Iwasaki Arihiro、Taguchi Raimu、Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
 
 Journal of Natural Products
 
 Volume: 86 Issue: 11 Pages: 2529-2538
- DOI
 10.1021/acs.jnatprod.3c00742
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-21KK0099, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870
[Journal Article] Fumagillin inhibits growth of the enteric protozoan parasite Entamoeba histolytica by covalently binding to and selectively inhibiting methionine aminopeptidase 22023
- Author(s)
 Watanabe Natsuki、Saito-Nakano Yumiko、Kurisawa Naoaki、Otomo Keisuke、Suenaga Kiyotake、Nakano Kentaro、Nozaki Tomoyoshi
- Journal Title
 
 Antimicrobial Agents and Chemotherapy
 
 Volume: 67 Issue: 11 Pages: 1-19
- DOI
 10.1128/aac.00560-23
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-22K07050
[Presentation] 未同定海洋シアノバクテリア由来新規環状デプシペプチド Shimojilide の単離および構造決定2025
- Author(s)
  仁井山瑞歩、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 未同定海洋シアノバクテリア由来新規環状デプシペプチド Shimojilide の単離および構造決定2025
- Author(s)
  仁井山瑞歩、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会（関西大学千里山キャンパス）
- Data Source
  KAKENHI-PROJECT-24K01639
[Presentation] 沖縄県産海洋シアノバクテリア由来新規鎖状リポペプチドsealgamideの全合成研究2025
- Author(s)
  土屋麻乃、若井和樹、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 未同定海洋シアノバクテリア由来、Kagimmicin の全合成研究2025
- Author(s)
  古川惇晟、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 沖縄県産海洋シアノバクテリア由来新規鎖状リポペプチドsealgamideの全合成研究2025
- Author(s)
  土屋麻乃、若井和樹、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会（関西大学千里山キャンパス）
- Data Source
  KAKENHI-PROJECT-24K01639
[Presentation] 海洋シアノバクテリア由来新規リポペプチド taketamines A-C の単離と構造決定2025
- Author(s)
  若井和樹、栗澤尚瑛、梅田海里、末永聖武
- Organizer
  日本化学会第105春季年会（関西大学千里山キャンパス）
- Data Source
  KAKENHI-PROJECT-24K01639
[Presentation] 強力な小胞体カルシウムポンプ阻害剤 iezoside の光親和性プローブ合成および結合部位の解析2025
- Author(s)
  能登明佳理、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 未同定海洋シアノバクテリア由来、Kagimmicin の全合成研究2025
- Author(s)
  古川惇晟、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会（関西大学千里山キャンパス）
- Data Source
  KAKENHI-PROJECT-24K01639
[Presentation] 海洋シアノバクテリア由来新規リポペプチド taketamines A-C の単離と構造決定2025
- Author(s)
  若井和樹、栗澤尚瑛、梅田海里、末永聖武
- Organizer
  日本化学会第105春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 強力な小胞体カルシウムポンプ阻害剤 iezoside の光親和性プローブ合成および結合部位の解析2025
- Author(s)
  能登明佳理、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第105春季年会（関西大学千里山キャンパス）
- Data Source
  KAKENHI-PROJECT-24K01639
[Presentation] 沖縄県産海洋シアノバクテリア由来新規リポペプチドの単離および構造決定2024
- Author(s)
  仁井山瑞歩、栗澤尚瑛、末永聖武
- Organizer
  第16回化学生態学研究会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 海洋シアノバクテリア由来新規抗マラリアペプチドの単離及び構造決定2024
- Author(s)
  梅田海里、栗澤尚瑛、末永聖武
- Organizer
  第16回化学生態学研究会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 新規リポペプチドsealgamideの単離と構造決定2024
- Author(s)
  若井和樹、栗澤尚瑛、梅田海里、末永聖武
- Organizer
  第35回海洋生物活性談話会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 新規天然物イエゾシドの作用機構解明2024
- Author(s)
  栗澤尚瑛
- Organizer
  2023年度文部科学省学術変革領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム成果発表会
- Invited
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 沖縄県産海洋シアノバクテリア由来新規リポペプチドukabamideの単離・構造決定・全合成・生物活性2024
- Author(s)
  萩原大尋、田口黎武、Ghulam Jeelani、野崎智義、岩崎有紘、栗澤尚瑛、末永聖武
- Organizer
  第35回海洋生物活性談話会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 海洋シアノバクテリア由来新規リポペプチドの単離と構造決定2024
- Author(s)
  若井和樹、栗澤尚瑛、梅田海里、末永聖武
- Organizer
  第16回化学生態学研究会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 海洋シアノバクテリア由来、抗マラリア活性ペプチドHiyajyamineの単離構造決定および全合成研究2024
- Author(s)
  梅田海里、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] SERCA結合部位同定を目的としたイエゾシド-アルキンプローブの合成研究2024
- Author(s)
  能登明佳理、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 海洋シアノバクテリア由来新規鎖状ペプチドhedoamideの合成研究2024
- Author(s)
  名倉旭哉、栗澤尚瑛、岩崎有紘、末永聖武
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 海洋シアノバクテリア由来新規リポペプチドsealgamideの単離と構造決定2024
- Author(s)
  若井和樹、栗澤尚瑛、梅田海里、末永聖武
- Organizer
  藍藻の分子生物学 2024
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 沖縄県産海洋シアノバクテリア由来新規リポペプチドOuhanamideの単離および構造決定2024
- Author(s)
  仁井山瑞歩、栗澤尚瑛、末永聖武
- Organizer
  藍藻の分子生物学 2024
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 抗トリパノソーマリポペプチド ukabamide の単離, 構造決定, 全合成, および生物活性2024
- Author(s)
  萩原大尋、岩﨑有紘、田口黎武、Ghulam Jeelani,、野崎智義、栗澤尚瑛、末永聖武
- Organizer
  第66回天然有機化合物討論会（同志社大学寒梅館）
- Data Source
  KAKENHI-PROJECT-24K01639
[Presentation] 未同定海洋シアノバクテリア由来新規リポペプチドの構造と生物活性2024
- Author(s)
  若井和樹、梅田海里、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 沖縄県産海洋シアノバクテリア由来新規リポペプチukabamideの単離、構造決定、全合成および生物活性2024
- Author(s)
  萩原大尋、田口黎武、岩﨑有紘、Ghulam Jeelani、野崎智義、栗澤尚瑛、末永聖武
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 沖縄県産海洋シアノバクテリア由来新規ペプチドの単離および構造決定2024
- Author(s)
  仁井山瑞歩、栗澤尚瑛、末永聖武
- Organizer
  第35回海洋生物活性談話会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] 抗トリパノソーマリポペプチドukabamideの単離、構造決定、全合成、および生物活性2024
- Author(s)
  萩原大尋、岩崎有紘、田口黎武、Ghulam Jeelani、野崎智義、栗澤尚瑛、末永聖武
- Organizer
  第66回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-23K19252
[Presentation] Structural Determination, Total Synthesis, and Biological Activity of Iezoside, a Highly Potent Ca2+-ATPase Inhibitor from Marine Cyanobacteria2023
- Author(s)
  Naoaki Kurisawa
- Organizer
  31st International Symposium on the Chemistry of Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252

1. 末永聖武 (60273215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

Kurisawa Naoaki 栗澤 尚瑛

Research Projects

Research Products

Co-Researchers

Exploration of novel natural products using molecular phylogeneticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

海洋産カルシウムポンプ阻害剤に基づく抗マラリア薬リード化合物の創製

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of a novel mode of action of iezoside based on the structure-activity relationshipPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Sealgamide: An Antitrypanosomal Lipopeptide Isolated from a Marine Okeania sp. Cyanobacterium2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and Total Synthesis of Ukabamide, an Antitrypanosomal Lipopeptide from a Marine Moorena sp. Cyanobacterium2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and structure determination of a new analog of polycavernosides from marine <i>Okeania</i> sp. cyanobacterium2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure-Activity Relationship Studies on Iezoside, a Highly Potent Ca2+ ATPase Inhibitor2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wajeepeptin, a Cytotoxic and Antitrypanosomal Cyclic Depsipeptide from a Marine Moorena sp. Cyanobacterium2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Bioorganic Study of Iezoside: A Novel SERCA Inhibitor from the Marine Cyanobacterium2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Total synthesis of acetylene-containing lipopeptides odookeanynes A and B2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and Structure Determination of Akunolides, Macrolide Glycosides from a Marine <i>Okeania</i> sp. Cyanobacterium2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fumagillin inhibits growth of the enteric protozoan parasite <i>Entamoeba histolytica</i> by covalently binding to and selectively inhibiting methionine aminopeptidase 22023

Author(s)

Journal Title

DOI

Data Source

[Presentation] 未同定海洋シアノバクテリア由来新規環状デプシペプチド Shimojilide の単離および構造決定2025

Author(s)

Organizer

Data Source

[Presentation] 未同定海洋シアノバクテリア由来新規環状デプシペプチド Shimojilide の単離および構造決定2025

Author(s)

Organizer

Data Source

[Presentation] 沖縄県産海洋シアノバクテリア由来新規鎖状リポペプチドsealgamideの全合成研究2025

Author(s)

Kurisawa Naoaki 栗澤尚瑛