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OGAWA Michio  小川 道雄

ORCIDConnect your ORCID iD *help
Researcher Number 30028691
External Links
Affiliation (based on the past Project Information) *help 2002: 熊本大学, 医学部・外科学第二講座, 教授
1992 – 2002: 熊本大学, 医学部, 教授
1999: Kumamoto University School of Medicine, Departmemt of Surgery II, Professor and Chairman, 医学部・外科学・第二講座, 教授
1999: 熊本大学, 医学部・外科学第二講座, 教授
1998: 教授 … More
1989: Osaka University Medical School Associate Professor, 医学部, 助教授
1988: 大阪大学, 医学部, 講師
1986: The 2nd Dept. of Surgery Osaka Univ. Medical School, Instractor, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
General surgery / Digestive surgery / Pathological medical chemistry
Except Principal Investigator
General surgery / Digestive surgery / Thoracic surgery / General pharmacology / Immunology / Biological Sciences
Keywords
Principal Investigator
SIRS / cytokine / acute pancreatitis / サイトカイン / 急性膵炎 / CARS / infection / organ dysfunction / 感染 / 臓器障害 … More / 好中球 / 多臓器不全 / pancreatic secretory trypsin inhibitor (PSTI) / サイトカイン拮抗物質 / second attack / neutrophil / 全身性炎症反応症候群 / エンドトキシン / ARDS / LPS / CINC / growth factor / PSTI receptor / 肺癌 / EGFレセプター / 膵分泌性トリプシン・インヒビター(PSTI) / PSTI受容体 / 上皮成長因子(EGF) / 培養細胞系 / 膵分泌性トリプシン・インヒビタ-(PSTI) / 成長因子 / 急性相蛋白 / 悪性腫瘍 / 侵襲 / インヒビター / 膵分泌性トリプシン / cytokine antagonist / 敗血症 / 重症急性膵炎 / 遠隔臓器障害 / 重症化機構 / 易感染性 / メディエータ / 臓器不全 / 臓器傷害 / scond attack / 重症度評価 / 炎症性サイトカイン / multiple organ failures / activated neutrophils / TNF-alpha / セルレイン / 活性化好中球 / 腫瘍壊死因子(TNF) / 縮小手術 / 多発癌 / P53 / 増殖細胞 / 腸上皮化生 / 胃癌 … More
Except Principal Investigator
NO / CD45RC / 発癌 / パーオキシナイトライト / 肝転移 / 転移 / DDR1 / HPLC / p53 / APC / K-ras / adenoma-carcinoma sequence / CCR7 / CCR5 / CD62L / colon 26 / LPS / pancreatic cancer / SIRS / サイトカイン / IL-6 / ウイルス感染病態 / 遺伝子変異 / フリーラジカル / 膵臓癌 / CD4^+T細胞 / 抗原提示 / HLA分子 / 細胞周期 / プロテアーゼ / 細胞増殖 / signal transduction / collagen / 細胞内シグナル / コラーゲン / recurrence / adjuvant therapy / systemic disease / prognosis / thoracoscopic surgery / molecular detection / micrometastasis / lung cancer / 前向き研究 / 再発 / 補助療法 / 全身病 / 予後 / 胸腔鏡手術 / 分子生物学的検出 / 微小転移 / 肺癌 / chemoinvasion / cell adhesion / cell motility / dissociation / cancer cell dissociation factor / liver metastasis / 浸潤 / 細胞浸潤 / 細胞接着 / 細胞運動 / 細胞解離 / 癌細胞解離因子 / PEROXYNITRITE / ECD / 8-NITROGUANOSINE / NITRATIVE STRESS / 3-NITROTYROSINE / NO-RELATED COMPOUNDS / ニトロソチオール / ニトロチロシン / ニトログアニン / ニトロトリプトファン / 電気化学検出法 / 8-ニトログアノシン / ニトロ化ストレス / 3-ニトロチロシン / NO関連物質 / tumor genes / glycogen phosphorylase / 'de novo' type carcinogenesis / colorectal carcinoma / 'de novo'型大腸癌 / 'de novo'型癌 / 癌遺伝子 / グリコーゲン・ホスホリラーゼ / 'de novo'型発癌 / 大腸癌 / epitope expression library / CLIP-substituted invariant chain / altered peptide ligand / molecular mimicry / self-reactive T cell / tolerance / autoimmune diseases / エピトープライブラリー / HLAクラスII分子 / 発現クローニング / CLIP / インバリアント鎖 / MHCクラスII分子 / エピトープ発現ライブラリー / CLIP置換インバリアント鎖 / アナログペプチド / 分子擬態 / 自己反応性T細胞 / 免疫応答 / 自己免疫疾患 / CD86 (B7-2) / CD80 (B7-1) / DENDRITIC CELL / UNRESPONSIVENESS / Red pulp / White pulp / CD86(B7-2) / CD80(B7-1) / CD45 / Dendritic cell / Unresponsiveness / nitroguanosine / carcinogenesis / viral pathogenesis / genomic mutation / peroxynitrite / nitric oxide / free radical / バーオキシナイトライト / Angiogenesis / Platelet-derived endothelial cell growth factor / Metastasis / Hepatocyte growth factor / Bronchioloalveolar cell carcinomao / Small cell lung cancer / Non-small cell lung cancer / びまん型 / 細気管支肺胞型腺型 / 血管新生 / 血小板由来血管内皮細胞増殖因子 / 肝細胞増殖因子 / 細気管支肺胞型腺癌 / 小細胞肺癌 / 非小細胞肺癌 / TUMOR-BEARING MOUSE / ORGAN FAILURE / CYTOKINE / colon26 / 担癌マウス / 臓器不全 / sialyl Lewis^a / E-selectin / TNF α / metastasis / 膵癌 / 血管内皮細胞 / 性と下院 / 外科浸襲 / 接着分子 / エラスターゼ活性 / 糖鎖 / 全身性炎症反応症候群 / 手術侵襲 / no-touch isolation / エラスターゼ / CA19-9 / E-セレクチン / TNFα / 癌転移 / IMMUNOLOGIC UNRESPONSIVENESS / RAT / TGF-beta / LIVER TRANSPLANTATION / EXTRATHYMIC DIFFERENTIATION / PHENOTYPE / CD8-POSITIVE T CELL / IL-18 / IL-10 / CD8^+T cell / CD4^+T cell / DST / liver fransplantation / immunologic unresponsiveness / rat / TGF-β / liver transplantation / 胸腺外分化 / phenotype / CD8 T cell / OX22 (CD45RC) / CD8 cells / CD4 cells / Th2 cells / Thymus / Rejection / Liver transplantation / Immunologic tolerance / OX22(CD45RC) / CD8細胞 / CD4細胞 / Th2細胞 / 胸腺 / 拒絶反応 / 肝移植 / 免疫学的寛容 / surgery / soluble IL-6receptor / trauma / 可溶性IL-6レセプター / 手術 / lL-6 / 可溶性lL-6レセプター / 侵襲 / Chemoembolization / Hepatocellular carcinoma (HCC) / Cisplatin suspended in lipiodol(CSL)-fibrin adhesive mixture / Transcatheter arterial chemoembolization (TACE) / Percutaneous transhepatic portal chemoembolization (PTPCE) / 肝動脈塞栓化学療法 / 原発性肝細胞癌 / 門脈塞〓化学療法 / 肝動脈塞〓術 / 原発性肝癌 / 門脈塞栓化学療法 / 肝動脈塞栓術 / ハムスター / BOP / 細胞解離因子 / 変異P53蛋白 / 変異Ras蛋白 / 抗腫瘍免疫 / 癌特異的ペプチド / がん浸潤 / 情報伝達 / 蛋白分解 / 腫瘍免疫 / 抗原ペプチド / がん特異抗原 / カテプシン / サイクリン / インヒビター / 癌 Less
  • Research Projects

    (29 results)
  • Co-Researchers

    (37 People)
  •  Analysis of the function and sigial transduction about Discoidin Domain Receptor (DDR)1 as a unique collagen receptor.

    • Principal Investigator
      ISHIKO Takatoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Analysis of pathophysiology in acute pancreatitis from the stand point of CARSPrincipal Investigator

    • Principal Investigator
      OGAWA Michio
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Molecular detection of circulating tumor cells by reverse transcriptase-polymerase chain reaction in patients with non-small cell lung cancer: A prospective study for clinical significance of micrometastasis

    • Principal Investigator
      YAMASHITA Jun-ichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Aichi Medical University
      Kumamoto University
  •  慢性感染に伴うフリーラジカル産生と発がん

    • Principal Investigator
      MAEDA Hiroshi
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  腸上皮化生の増殖細胞の性格に基づいた腸型胃癌発生のメカニズムの解明とその臨床応用Principal Investigator

    • Principal Investigator
      小川 道雄
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  Development of analysis for all biologically relevant derivatives of NO

    • Principal Investigator
      AKAIKE Takaaki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Analysis of the mechanism of liver metastasis in pancreatic cancer -purification and gene cloning of cancer cell dissociation factor-

    • Principal Investigator
      EGAMI Hiroshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  Free radical generation in chronic infection and its implication in carcinogenesis

    • Principal Investigator
      MAEDA Hiroshi
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  Analysis of pathophysiology in acute pancreatitis from the stand point of SIRS and CARSPrincipal Investigator

    • Principal Investigator
      OGAWA Michio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  MECHANISMS OF IMMUNOLOGIC UNRESPONSIVENESS : DIFFERENTIATION OF DENDRITICCELLS BY CHEMOKINE

    • Principal Investigator
      MORI Katsutaka, 山口 康雄
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  THE DIVESITY IN ANTIGEN RECOGNITION AND RESPONSE OF ANTIGEN-SPECIFIC HUMAN CD4^+ T-CELL CLONES

    • Principal Investigator
      NISHIMURA Yasuharu
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Investigation of 'de novo' type colorectal carcinogenesis

    • Principal Investigator
      SHIMADA Shinya
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  Stimulation of Cancer Metastases in Systemic Inflammatory Response Syndrome

    • Principal Investigator
      HIROTA Masahiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  BASIC RESEARCH FOR MECHANISM OF ORGAN FAILURE IN CANCER PATIENTS WITH PARANEOPLASTIC SYNDROME-PROPHYLAXY AND TREATMENT OF PARANEOPLASTIC SYNDROME BY REGULATION OF CYTOKINE PRODUCTION-

    • Principal Investigator
      MITA Seiji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Mechanism of Lung Cancer Spread: Role of Protease and Its Inhibitor

    • Principal Investigator
      YAMASHITA Jun-ichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kumamoto University School of Medicine
  •  Analysis of pathophysiology in acute pancreatitis from the stand point of second attack theoryPrincipal Investigator

    • Principal Investigator
      OGAWA Michio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  IMMUNOLOGIC UNRESPONSIVENESS : EXTRATHMIC T CELL DIFFERENTIATION AND PHENOTYPES OF CD8 T CELLS

    • Principal Investigator
      YAMAGUCHI Yasuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  細胞増殖の制御とプロテアーゼ

    • Principal Investigator
      木南 英紀
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  癌特異的HLA結合性ペプチドによる抗腫瘍免疫応答の誘導

    • Principal Investigator
      西村 泰治
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  膵臓癌における肝転移機構の解析:膵癌の産生する細胞解離因子の解明

    • Principal Investigator
      EAGAMI Hiroshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto University
  •  Analysis of pathophysiology in acute pancreatitis from the stand point of systemic inflammatory response syndromePrincipal Investigator

    • Principal Investigator
      OGAWA Michio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  細胞増殖の制御とプロテアーゼ

    • Principal Investigator
      木南 英紀
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  癌特異的HLA結合性ペプチドによる抗腫瘍免疫応答の誘導

    • Principal Investigator
      NISHIMURA Yasuharu
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  Prolonged rat hepatic allograft survival by intrathymic administration of donor antigens : the role of antigen presenting cells (dendritic cells) and Th2 cells

    • Principal Investigator
      YAMAGUCHI Yasuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Mediators for the aggravation of acute pancreatitis-the role of cytokies and activated neutrophilsPrincipal Investigator

    • Principal Investigator
      OGAWA Michio
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  Analysis of serum soluble IL-6 receptor in patients with surgical trauma

    • Principal Investigator
      SAKAMOTO Kiyoshi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kumamoto University
  •  A new approach to arterial and portal chemoembolization therapy for unresectable hepatocellular carcinoma

    • Principal Investigator
      KATAFUCHI Shigeru
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kumamoto university medical school
  •  Production of pancreatic secretory trypsin inhibitor (PSTI) as a growthstimulating factor and characterization of its specific receptorsPrincipal Investigator

    • Principal Investigator
      OGAWA Michio
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University Medical School
  •  Expression of pancreatic secretory trypsin inhibitor: After surgical stress and its' significance.Principal Investigator

    • Principal Investigator
      OGAWA Michio
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      OSAKA UNIVERSITY
  • 1.  MORI Katsutaka (10040213)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  YAMAGUCHI Yasuo (90253757)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  EAGAMI Hiroshi (00264284)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  HIROTA Masahiko (80284769)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  NISHIMURA Yasuharu (10156119)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  MAEDA Hiroshi (90004613)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  MIYAMOTO Youichi (20295132)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  AKAIKE Takaaki (20231798)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  SAWA Tomohiro (30284756)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SHIMADA Shinya (10284746)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KATAFUCHI Shigeru (50233747)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  IKEI Satoshi (90136705)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MITA Seiji (10212234)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  YAMASHITA Jun-ichi (20279285)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  MIYAUCHI Keisuke (70209857)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  木南 英紀 (10035496)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  木戸 博 (50144978)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  岸本 健雄 (00124222)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  川島 誠一 (60008571)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  鈴木 紘一 (80011948)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  松下 祥 (50167649)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  SAKAMOTO Kiyoshi (10162306)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  MITA Seiji (10671125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  IRIE Atsushi (30250343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SENJU Satoru (50274709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SUZUKI Misao (60253720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  ISHIKO Takatoshi (00343351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  MURATA Atsuo (00200288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  吉良 潤一 (40183305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  遠藤 文夫 (00176801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  BEPPU Toru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  MIZUNO Kyousuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  NISHINO Hirohito
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  SHIBATA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  緒方 健一
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  中口 和則
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  NAKAGUCHI Kazunori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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