OHNO Motonori 大野素徳

… Alternative Names

OHNO Ryuichi 大野素徳

Less

Researcher Number	30038434
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005: Sojo University, Faculty of Biotechnology and Life Science, Professor, 生物生命学部, 教授 2003 – 2004: 崇城大学, 工学部, 教授 2000 – 2001: 崇城大学, 工学部, 教授 1988 – 1995: Department of Chemistry, Faculty of Science, 理学部, 教授 1987: 九州大学, 理学部, 助教授
Review Section/Research Field	Principal Investigator 物質生物化学 / Biodiversity/Systematics / 系統・分類 / 天然物有機化学 Except Principal Investigator Structural biochemistry / 物質生物化学 / 天然物有機化学 / Applied biochemistry / Bioorganic chemistry
Keywords	Principal Investigator cDNA / アミノ酸配列 / ハブ毒 / 適応進化 / 加速進化 / 遺伝子 / ホスホリパーゼA_2 / Amino acid sequence / 南西諸島 / 分子進化 … More / Phospholipase A_2 / Trimeresurus flavoviridis / 遺伝子工学 / アイソザイム / 奄美ハブ毒 / 毒腺アイソザイム / ハブ / Basic protein / Flavoxobin / Coagulant enzyme / Fibrinogen / Trimeresurus flavoviridis venom / 二機能性酵素 / クロストリパイン / 一次構造 / 金属プロテアーゼ / 塩基性タンパク質 / 凝固酵素 / フラボキソビン / フィブリノーゲン / cDNA cloning / Phospholipase A_2 isozymes / Phylogeny / Evolution / Southwestern islands of Japan / Snakes of Trimeresurus genus / 第四紀陸橋 / 南西諸島・台湾 / cDNAクローニング / ホスホリパーゼA_2アイソザイム / 系統 / 進化 / マムシ亜科ハブ属ヘビ / Adaptive evolution / Feeding habit / Pseudogene / Gene mutation / Venom-gland phospholipase A2 isozymes / Isolated environments / Southwestem islands of Japan / 孤立 / ホスホリパービA_2アイソザイム / クロマトグラフィー / 食性 / 偽遺伝子 / 遺伝子変異 / 毒腺ホスホリパーゼA_2アイソザイム / 孤立環境 / isozyme / adaptive / accelerated evolution / neurotoxin / phospholipase A2 / molecular evolution / snake venom / 神経毒 / ホスホリハ-ゼA_2 / ヘビ毒腺 / Zinc protease inhibitor / Zinc proteases / Inhibitor against myolytie factor / Lys-49-phospholipase A_2 / Myolytic factor / Trimeresurus flavoviridis serum inhibitor / Trimeresurus flavoviridis venom enzyme / T_2-プロテア-ゼ結合タンパク質 / T_2-プロテア-ゼ / ハブ毒酵素結合タンパク質 / 脱分極 / N端アミノ酸配列 / 糖タンパク質 / 塩基性タンパク質I結合タンパク質 / ハブ血液 / 筋壊死活性 / 塩基性タンパク質I / 亜鉛プロテアーゼインヒビター / 亜鉛プロテアーゼ / 筋壊死因子インヒビター / 筋壊死因子 / Lys-49-ホスホリパーゼA_2 / ハブ血清インヒビター / ハブ毒酵素 / Physiological activities / Accelerated substitutions / Gene Structures / Expression / cDNAs / Isozymes / Phospholipase A2 / Trimeresurus floavoviridis / ポリモルフィズム / 僞遺伝子 / ゲノム遺伝子 / 発現 / 低活性型Lysー49ーホスホリパ-ゼA_2 / 高活性型Aspー49ーホスホリパ-ゼA_2 / 徳之島ハブ毒 / 融合タンパク質 / 変異タンパク質 / ダーウィン進化 / ハブ毒腺 / Genome DNA / Genetic engineering / Isozyme / イソ酵素 / α→β転位 / アクロモバクタ-プロテア-ゼI / ゲノムDNA / ホスホリパ-ゼA_2 / セリンプロテアーゼ / TATAボックス結合タンパク質 / ホスホリバーゼA_2 / マムシ科ヘビ / グリーンハブ / マムシ科へび … More Except Principal Investigator ペプチド合成 / エンケファリン / オピオイド受容体 / error-prone DNA polymerase / snake (Habu) venom / D-Glucanase / Xylanase A / Factor G / cDNAクローニング / アフィニティラベリング / 受容体サブタイプ / キモトリプシン阻害ペプチド / トリプシン阻害ペプチド / 植物起源インヒビタ- / プロテア-ゼインヒビタ- / Peptide synthesis / Chymotrypsin inhibitory peptide / Trypsin inhibitory peptide / Plant inhibitor / Protease inhibitor / 植物起源インヒビター / プロテアーゼインヒビター / トリプトシン阻害ペプチド / Protobothrops (Trimeresurus) flavoviridis / Trimeresurus flavoviridis / snake venom / error-prone DNAポリメラーゼ / Protobothrops (Trimeresurus flavoviridis / error-prone DNA polymerase polymerase / Curdlan / LPS / Serine protease / beta-Glucan / Limulus / セリンプロテアーゼチモーゲン / 生体防御系 / 無脊椎動物 / 体液凝固機構 / G因子 / (1→3)β-D-グルカン / LPS結合タンパク質 / レクチン / LPS-レセプター / デフェンシン / タキプレシン / 抗リポ多糖因子 / 体液凝固因子 / カードラン / リポ多糖(LPS) / セリンプロテアーゼ / β-グルカン / カブトガニ血球 / 重点領域 / 分子設計 / 構造活性相関 / ペプチド三次構造 / 生体内信号 / ペプチド科学 / 生体機能性ペプチド / 立体制約アミノ酸 / 鎮痛性ペプチド / 機能構造 / グラミシジンS / 抗生ペプチド / 多剤耐性克服 / Pー糖タンパク質 / 種子発芽促進 / 生理的機能 / ダイズインヒビタ- Less

Elucidation of DNA replication mechanism of Protobothrops flavoviridis (Habu snake)
- Principal Investigator
  
  ODA-UEDA Naoko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Sojo University
Analysis of evolution and phylogeny of snakes of Trimeresurus genus in the southwestern islands of Japan based on structural information of venom-gland isozymesPrincipal Investigator
- Principal Investigator
  
  OHNO Motonori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biodiversity/Systematics
- Research Institution
  Sojo University
EVOLUTIONARY STUDY OF ENVIRONMENT-DEPENDENT MUTATIONS OF TRIMERESURUS FLAVOVIRIDIS VENOM-GLAND PHOSPHOLIPASE A2 ISOZYME GENESPrincipal Investigator
- Principal Investigator
  
  OHNO Ryuichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  系統・分類
- Research Institution
  SOJO UNIVERSITY
マムシ科ヘビ毒膜アイソザイムの普遍的加速進化Principal Investigator
- Principal Investigator
  
  大野素徳
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
ヒト脳δ型オピオイド受容体サブタイプのcDNAクローニングとリガンド結合部位解析
- Principal Investigator
  
  下東康幸
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
Accelerated Evolution of Venom Gland IsozymesPrincipal Investigator
- Principal Investigator
  
  OHNO Motonori
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYUSHU UNIVERSITY
毒腺アイソザイムの加速進化Principal Investigator
- Principal Investigator
  
  大野素徳
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
機能性ペプチドの分子設計における新展開
- Principal Investigator
  
  宗像英輔
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  University of Tsukuba
アフィニティラベリングによるオピオイド受容体の結合部位の決定
- Principal Investigator
  
  下東康幸
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
オピオイド受容体単離のための新規アフィニティクロマトグラフィー
- Principal Investigator
  
  下東康幸
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
Role of Limulus Hemocytes in the Biological Defense System.
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  物質生物化学
- Research Institution
  KYUSHU UNIVERSITY
Pー糖タンパク質の機能構造破壊による多剤耐性克服
- Principal Investigator
  
  下東康幸
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
LeuーエンケファリンとMetーエンケファリンの機能は異なる
- Principal Investigator
  
  下東康幸
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
Protein Engineering and Gene Analysis of Trimeresurus flavoviridis Phospholipase A_2 IsozymesPrincipal Investigator
- Principal Investigator
  
  OHNO Motonori
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
Protein Chemistry and Basic Research for Application of Inhibitors from Trimeresurus flavoviridis Serum against Its Venom EnzymesPrincipal Investigator
- Principal Investigator
  
  OHNO Motonori
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  天然物有機化学
- Research Institution
  KYUSHU UNIVERSITY
植物起源プロテア-ゼインヒビタ-の本来の生理的機能は何か
- Principal Investigator
  
  WAKI Michinori
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  天然物有機化学
- Research Institution
  Kyushu University
Analysis of the Structural Elements Required for Highly Efficient CatalysisPrincipal Investigator
- Principal Investigator
  
  OHNO Motonori
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
Design and Synthesis of Novel Inhibitors Modeled on Plant Protease Inhibitors
- Principal Investigator
  
  WAKI Michinori
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  天然物有機化学
- Research Institution
  Kyushu University
Determination of Primary Structures of Fibrinogen-specific proteases from Trimeresurus flavoviridis VenomPrincipal Investigator
- Principal Investigator
  
  OHNO Motonori
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University

All 2005 2004 2003

All Journal Article

[Journal Article] Molecular diversity and acclerated evolution C-type lectin like proteins from snake venom2005
- Author(s)
  Ogawa, T., Chijiwa, T., Oda-Ueda, N., Ohno, M
- Journal Title
  
  Toxicon 45
  
  Pages: 1-14
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Amino acid sequence of a basic aspartate-49-phospholipase A_2 from Trimeresurus flavoviridis and phylogenic analysis of Crotalinae venom phospholipase A_22005
- Author(s)
  Chijiwa, T., Abe, L., Ogawa, T., Nikandrov, N.N., Hattori, S., Oda-Ueda, N., Ohno, M.
- Journal Title
  
  Toxicon 46
  
  Pages: 185-195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Amino Acid Sequence of a basic Aspartate-49-phospholipase A2 from Trimeresurus flavoviridis Venom and Phylogenetic Analysis of Crotalinae Venom phospholipase A22005
- Author(s)
  Chijiwa, T.Abe, L., Ogawa, T., Nikandrov, N.N., Hattori, S., Oda-Ueda, N., Ohno, M
- Journal Title
  
  Toxicon 46
  
  Pages: 185-195
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Amino acid sequence of a basic aspartate-49-phospholipase A_2 from Trimeresurus flavorirdis and phylogenic analysis of Crotalinae venom phosholipase A_22005
- Author(s)
  Chijiwa, T., Abe, L., Ogawa, T., Nikandrov, M.N., Hattori, S., Oda-Ueda, N., Ohno,M.
- Journal Title
  
  Toxicon 46
  
  Pages: 185-195
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Molecular Diversity and accelerated evolution of C-type lectin-like proteins from snake venom2005
- Author(s)
  Ogawa, T., Chijiwa, T., Oda-Ueda, N., Ohno, M.
- Journal Title
  
  Toxicon 45
  
  Pages: 1-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Molecular diversity and accelerated evolution of C-type lectin-like proteins from snake venom2005
- Author(s)
  Ogawa, T., Chijiwa, T., Oda-Ueda, N, Ohno, M.
- Journal Title
  
  Toxicon Vol 45,No 1
  
  Pages: 1-14
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Diversity and accelerated evolution of C-type lectin-like proteins from snake venom2005
- Author(s)
  Ogawa, T., Chijiwa, T., Oda-Ueda, N., Ohno, M., Molecular Toxicon, 45, 1-14(2005)
- Journal Title
  
  Toxicon 45
  
  Pages: 1-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Science in Protobothrops flavoviridis venom.(review article)2004
- Author(s)
  Oda-Ueda, N., Chijiwa, T., Ohno, M.
- Journal Title
  
  Kagaku to Seibutsu. [Chemistry and biology] 42
  
  Pages: 687-693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] ハブ毒を科学する-機能の多様性と加速進化2004
- Author(s)
  上田直子, 千々岩崇仁, 大野素徳
- Journal Title
  
  化学と生物 42
  
  Pages: 687-693
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] ハブ毒を科学する一機能の多様性と加速進化2004
- Author(s)
  上田直子, 千々岩崇仁, 大野素徳
- Journal Title
  
  化学と生物 42
  
  Pages: 687-693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] ハブ毒を科学する2004
- Author(s)
  上田直子, 千々岩宗仁, 大野素徳
- Journal Title
  
  化学と生物 42
  
  Pages: 687-693
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] ハブ毒を科学する2004
- Author(s)
  上田直子, 千々岩崇仁, 大野素徳
- Journal Title
  
  化学と生物 Vol 42,No 10
  
  Pages: 687-693
- Data Source
  KAKENHI-PROJECT-16580079
[Journal Article] Necrosis and regeneration of the skeletal muscle without a marked hemorrhage induced in the rat by envenomation of Trimeresurus flavoviridis venom and its components, phospholipase A_2 isozymes2003
- Author(s)
  Kitano, M., Hirano, M., Ishihara, T., Hashima, T., Umemura, E., Yoshida, A., Hattori, S., Ueda, N., Ohno, M.
- Journal Title
  
  The Progress Report of the 2000 and 2001 Survey of the Research Project "Social Homeostasis of Small Islands in an Island Zone" Occasional Papers 38
  
  Pages: 105-112
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] Interisland mutation of a novel phospholipase A_2 from Trimeresurus flavoviridis venom and evolution of Crotalinae group II phospholipases A_22003
- Author(s)
  Chijiwa, T., Hamai, S., Tsubouchi, S., Ogawa, T., Deshimaru, M., Oda-Ueda, N., Hattori, S., Kihara, H., Tsunasawa, S., Ohno, M.
- Journal Title
  
  Journal of Molecular Evolution 57
  
  Pages: 547-554
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] Molecular evolution of myotoxic phospholipases A_2 from snake venom2003
- Author(s)
  Ohno, M.et al.
- Journal Title
  
  Toxicon 42
  
  Pages: 841-854
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] ハブ毒を科学する.多様な生理機能と加速進化2003
- Author(s)
  上田直子, 千々岩崇仁, 大野素徳
- Journal Title
  
  化学と生物 42
  
  Pages: 687-693
- NAID
  10016520015
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] Interisland evolution of Trimeresurus flavoviridis venom phospholipase A_2 isozymes2003
- Author(s)
  Chijiwa, T., Yamaguchi, Y., Ogawa, T., Deshimaru, M., Nobuhisa, I., Nakashima, K., Oda-Ueda, N., Fukumaki, Y., Hattori, S., Ohno, M.
- Journal Title
  
  Journal of Molecular Evolution 56
  
  Pages: 286-293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] Prevention of muscle necrosis induced in rats after envenomation of Trimeresurus flavoviridis (Aamami-Oshima island) venom and Its components, phospholipase A_2 isozymes2003
- Author(s)
  Kitano, M., Yoshida, A., Hattori, S., Ohno, M.
- Journal Title
  
  The Annals of Kagoshima University Dental School 23
  
  Pages: 15-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570089
[Journal Article] Molecular evolution of myotoxic phospholipases A_22003
- Author(s)
  Ohno, M., Chijiwa, T., Oda-Ueda, N., Ogawa, T., Hattori, S.
- Journal Title
  
  Toxicon 42
  
  Pages: 841-854
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570089

1. SHIMOHIGASHI Yasuyuki (00211293)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. OGAWA Tomohisa (80240901)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. AOYAGI Haruhiko (80037267)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. WAKI Michinori (30037212)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. HATTORI Shosaku (00164864)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. UEDA Naoko (70211828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. IWANAGA Sadaaki (90029942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAWADA Katsuhisa (20029507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TOH Yoshihiro (60037265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWABATA Shun-ichiro (90183037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. CHIJIWA Takahito (30331060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. 宗像英輔 (60072766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 藤井信孝 (60109014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 木曾良明 (40089107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 塩入孝之 (20012627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 下西康嗣 (00029951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KIHARA Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MENEZ Andre

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 小田直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results

OHNO Motonori 大野 素徳

OHNO Ryuichi 大野 素徳

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of evolution and phylogeny of snakes of Trimeresurus genus in the southwestern islands of Japan based on structural information of venom-gland isozymesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EVOLUTIONARY STUDY OF ENVIRONMENT-DEPENDENT MUTATIONS OF TRIMERESURUS FLAVOVIRIDIS VENOM-GLAND PHOSPHOLIPASE A2 ISOZYME GENESPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マムシ科ヘビ毒膜アイソザイムの普遍的加速進化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Accelerated Evolution of Venom Gland IsozymesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

毒腺アイソザイムの加速進化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein Engineering and Gene Analysis of Trimeresurus flavoviridis Phospholipase A_2 IsozymesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein Chemistry and Basic Research for Application of Inhibitors from Trimeresurus flavoviridis Serum against Its Venom EnzymesPrincipal Investigator

Principal Investigator

Project Period (FY)

OHNO Motonori 大野素徳

OHNO Ryuichi 大野素徳