OTANI Hajime 大谷元

Researcher Number	30109201
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012: 信州大学, (連合)農学研究科(研究院), 教授 2008 – 2012: Shinshu University, 農学研究科, 教授 2009: Shinshu University, 大学院・農学研究科, 教授 2007: Shinshu University, 大学院・農学研究科, 教授 2006: SHINSHU UNIVERSITY, Graduate school of agriculture, Professor, 大学院農学研究科, 教授 … More 2004 – 2005: 信州大学, 大学院・農学研究科, 教授 2001 – 2002: 信州大学, 大学院・農学研究科, 教授 1996 – 2000: 信州大学, 農学部, 教授 1993 – 1994: 信州大学, 農学部, 教授 1990 – 1991: Shinshu University, Faculty of Agriculture, Professor, 農学部, 教授 1986 – 1990: 信州大学, 農学部, 助教授 Less
Review Section/Research Field	Principal Investigator Zootechnical science/Grassland science / Zootechnical science/Grassland science / 畜産化学 Except Principal Investigator 畜産化学
Keywords	Principal Investigator 牛乳 / カゼインホスホペプチド / 機能性食品素材 / phosphorylated dextrin / リン酸化デキストリン / SerP-X-SerP / 機能性飼料 / IgA / 機能性食品事材 / kappa-casein … More / κ-カゼイン / リンパ球 / 牛乳IgG / I型アレルギー軽減 / サイトカイン生産調節 / 経口投与試験 / 鶏卵 / piglet / functional feed / DNA microarray / stimulation of active absorption of calcium / cellular immunostimulation / mucosal immunostimulation / casein phosphopeptide / IL-6 / IL-5 / CPP / 機能性飼料素材 / 粘膜免疫 / トールライクレセプター-4 / 発酵乳製品 / 腸管IgA産生促進 / 仔豚飼料 / 抗腫瘍作用 / カルシウム吸収促進 / IgA産生 / マウス飼料 / 免疫担当細胞 / 仔豚 / DNAマイクロアレイ / カルシウム能動吸収促進 / 細胞性免疫促進 / 粘膜IgA産生促進 / functional foodstuffs / immunoenhancing peptide / casein digests / anti-allergic peptides / IgA-stimulatory peptide / casein phosphopeptides / ジホスホトリペプチド / 腸管免疫 / 非アレルゲン性 / 免疫促進 / 経口摂取 / 粘膜免疫増強 / カゼイン消化物 / アレルギー軽減ペプチド / IgA産生促進ペプチド / Lymphocytes / Oral administration / Mitogenic activity / Intestinal IgA / Cytokines / Immunoregulator / Casein phosphopeptides / Milk casein / 特定保健用食品 / マイトージェン活性 / リンパ球増殖 / 免疫グロブリン生産 / 豚 / 経口投与 / 免疫賦活 / カゼイン / 細胞培養 / 動物試験 / 腸管IgA応答 / 免疫調節 / 牛乳カゼイン / human casein / apoptosis / mitogen / immunoglobulin production / lymphocytes / milk proteins / IL-1レセプターアンタゴニスト / IL-2レセプター / グリコマクロペプチド / 免疫抑制作用 / 人乳 / 人乳カゼイン / アポトーシス / マイト-ジェン / 抗体生産 / 牛乳タンパク質 / avian egg proteins / lactoferrin / anti-anaphylactic / inhibition / proliferation / macrophages / 1ymphocytes / アビジン / 抗アナフィラキシー / 卵白蛋白質 / ラクトフェリン / k-カゼイン / 抗アナフィラキシ- / 抑制活性 / 増殖・分化 / マクロファージ / ビール酵母・IgG混合物 / たんぱく質 / アレルギー・ぜんそく / 免疫学 / 畜産学 / 脱顆粒 / マウス / 抗原・IgG複合体 / 食品 / 安全性 / 乳利用 / マウス毒性 / I 型アレルギー軽減 / 抗原抗体複合物 / ビール酵母 / アレルギー軽減 / 牛乳抗体 / マウス経口摂取 / 免疫グロブリン / Th1優位 / アレルギー軽減作用 / 酵母とそのIgGの経口投与 / I型アレルギー / アレルギー自然発症マウス / 肥満細胞 / 制御性T細胞 / IgE産生細胞数 / Th2バランス / Th1 / 後天的I型アレルギー / パン酵母とそのIgGの経口投与 / パン酵母特異ヤギ乳IgG / 花粉症軽減 / 抗アレルギー作用 / 獲得液性免疫抑制 / 遺伝子の網羅的解析 / マウス経口投与 / 抗原・IgG複合物 / 乳汁IgG / 細胞性免疫増強 / 液性免疫抑制 / 細胞培養系 / エフェクター活性 / 抗原結合活性 / 牛乳IgG安定性 / CD83 / CD80 / パイエル板 / Fcγ受容体 / 抗原提示細胞 / 抗アレルギー食品素材 / IgG1 / 消化性 / プロテア-ゼ / 免疫原性 / ポリエチレングリコ-ル / 化学修飾 / IgY / 卵黄抗体 / 抗体の比較検討 / 抗体のプロテア-ゼ消化性 / IgY抗体 / 特異抗体 / 鶏 … More Except Principal Investigator 抗変異原性 / 発酵乳 / 乳酸菌細胞壁 / 変異原性 / Lactobacillus / Lactococci / Fermented milk / Antitumor activity / 状質乳 / ヨーグルト / 抗腫瘍活性 / 乳酸桿菌 / 乳酸球菌 / Lactic Acid Bacteria / Superoxide Dismutase / Fermented Milk / Adjuband Effect / Antitumor / Antimutagenicity / Microbial Polysaccharides / マイドジェル活性 / アジェバンド効果 / ダディヒ / ケフィ-ル / 微生物生産多糖類 / 乳酸菌 / ス-パ-オキシドジスムタ-ゼ / アジュバンド効果 / 抗腫瘍性 / 微生物生産多糖 / Ames株TA98 / 発酵乳スターター Less

Studies on anti-allergic properties of a mixture of Saccaromyces pastorianus and its specific cow's milk antibodyPrincipal Investigator
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Shinshu University
Elucidation of active immunomodulatory function of milk IgG and development of its utilityPrincipal Investigator
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Shinshu University
ウシIgGの新規免疫調節食品素材としての利用面の探索Principal Investigator
- Principal Investigator
  
  大谷元
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Shinshu University
Development of a functional feed on the basis of immunostimulatory action of casein phosphopeptidePrincipal Investigator
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  SHINSHU UNIVERSITY
Development of non-allergic peptide preparation having mucosal immunostimulatory abilityPrincipal Investigator
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Shinshu University
Elucidation of immnoregulating function of casein phosphopeptidePrincipal Investigator
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Shinshu University
Immunosuppresive action of milk k-casein and its digestsPrincipal Investigator
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Shinshu University
Studies on the immuno-modulating ability of bovine milk and avian eggsPrincipal Investigator
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Shinshu University
化学修飾による鶏卵黄抗体の機能改善Principal Investigator
- Principal Investigator
  
  大谷元
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  畜産化学
- Research Institution
  Shinshu University
特異抗体の分離源としての鶏卵利用Principal Investigator
- Principal Investigator
  
  大谷元
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  畜産化学
- Research Institution
  Shinshu University
Studies on Antimutagenic and Antitumoral Activities of Microbial Polysaccharides
- Principal Investigator
  
  HOSONO Akiyoshi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  畜産化学
- Research Institution
  Shinshu University
発酵乳スターター菌体成分の抗変異原性
- Principal Investigator
  
  細野明義
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  畜産化学
- Research Institution
  Shinshu University
Studies on anti-carcinogenic activity of fermented milk and its application
- Principal Investigator
  
  ADACHI Susumu
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  畜産化学
- Research Institution
  TOHOKU UNIVERSITY
発酵乳の抗変異原性に関する研究
- Principal Investigator
  
  HOSONO Akiyoshi
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  畜産化学
- Research Institution
  Shinshu University

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

[Book] 畜産学入門2012
- Author(s)
  大谷　元　（唐澤　豊・大谷　元・菅原邦生編著）
- Publisher
  文永遠堂出版
- Data Source
  KAKENHI-PROJECT-22580306
[Book] 畜産学入門(唐澤豊・大谷元・菅原邦生編)2012
- Author(s)
  大谷元
- Publisher
  文永堂出版
- Data Source
  KAKENHI-PROJECT-22580306
[Book] 母乳の力～牛乳タンパク質に秘められた生体防御機能2011
- Author(s)
  大谷元(単著)
- Total Pages
  183
- Publisher
  食品資材研究会
- Data Source
  KAKENHI-PROJECT-22580306
[Book] 母乳の力:母乳タンパク質に秘められた生体防御機能2011
- Author(s)
  大谷元
- Total Pages
  183
- Publisher
  食品資材研究会
- Data Source
  KAKENHI-PROJECT-22580306
[Book] 日本酪農科学会創立 60 周年記念誌2011
- Author(s)
  大谷元,斎藤忠夫
- Publisher
  日本酪農科学会
- Data Source
  KAKENHI-PROJECT-22580306
[Book] ナチュラルチーズ事典2010
- Author(s)
  大谷元監修
- Total Pages
  207
- Publisher
  日東書院
- Data Source
  KAKENHI-PROJECT-22580306
[Book] 「現代チーズ学」(齊藤忠夫・堂迫俊一・井越敬司編), 4. 5チーズとホエイに含まれるタンパク質の免疫科学2008
- Author(s)
  大谷元
- Publisher
  食品資材研究会
- Data Source
  KAKENHI-PROJECT-19580307
[Book] 「現代チーズ学」(1.1チーズの起源と歴史(pp. 3-13), 4.5チーズとホエイに含まれるタンパク質の免疫科学(pp. 333-345)を執筆)2008
- Author(s)
  大谷元
- Total Pages
  485
- Publisher
  食品資材研究会
- Data Source
  KAKENHI-PROJECT-19580307
[Book] 「新編畜産ハンドブック」, 9.1.1乳の機能と品質2006
- Author(s)
  大谷元
- Publisher
  (株)講談社サイエンスティフィク
- Data Source
  KAKENHI-PROJECT-16380180
[Book] 機能性飼料素材CPPのはなし〜骨をつくり,身体をつくるカゼインホスホペプチドの粘膜免疫増強機能〜感染防御資料素材としての背景(CPP研究会編)2005
- Author(s)
  大谷元
- Total Pages
  191
- Publisher
  ベネット社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Book] Casein Phosphopeptide for Functional Resorces2005
- Author(s)
  Otani, H.
- Total Pages
  191
- Publisher
  VENET Publisher
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Book] CPPのはなし(CPP研究会編)2005
- Author(s)
  大谷元
- Publisher
  ベネット社(印刷中)
- Data Source
  KAKENHI-PROJECT-16380180
[Book] 牛乳の機能と品質開発(新編畜産ハンドブック)2005
- Author(s)
  大谷元
- Publisher
  講談社(印刷中)
- Data Source
  KAKENHI-PROJECT-16658103
[Book] 骨をつくり、身体をつくる機能性飼料素材CPPのはなし(CPP研究会編)2005
- Author(s)
  大谷元
- Total Pages
  191
- Publisher
  ベネット社
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] ビール酵母とその牛乳抗体のマウスにおけるアレルギー軽減作用と急性毒性に関する検討2013
- Author(s)
  森崎健太郎,松田孝裕,須賀正喜,荻田佑,平松浩二,下里剛士,大谷元
- Journal Title
  
  北信越畜産学会報
  
  Volume: 第106号 Pages: 35-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] 牛乳および乳製品の免疫科学的研究の展開2011
- Author(s)
  大谷元
- Journal Title
  
  ミルクサイエンス
  
  Volume: 60巻 Pages: 199-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] パン酵母とそれに特異的なIgGを含むシバヤギ乳IgG分画のマウスI型アレルギー軽減作用2011
- Author(s)
  大谷元
- Journal Title
  
  New Food Industry
  
  Volume: 53(8) Pages: 28-38
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] Anti-allergic effects of a mixture of Saccharomyce cerevisiae and its specific goat's milk immunoglobulin G-rich fraction on ovalbumin-snecific BALB/c mice2011
- Author(s)
  Sekimura Y, Shimosato T, Otani H
- Journal Title
  
  Milchwissenschaft
  
  Volume: 66 Pages: 7-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] A matured fruit extract of date palm tree (Phoenix dactylifera L.) stimulates the cellular immune system in mice2011
- Author(s)
  Karasawa K, Uzuhashi Y, Hirota M, Otani H
- Journal Title
  
  Agriculture and Food Chemistry
  
  Volume: 59 Pages: 11287-11293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] Anti-allergic effects of a mixture of Saccharomyce cerevisiae and its specific goat' s milk immunoglobulin G-rich fraction on ovalbuminsensitized BALB/c mice2011
- Author(s)
  Sekimura Y, Shimosato T and OtaniH
- Journal Title
  
  Milchwissenschaft
  
  Volume: 66 Pages: 7-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] 牛乳および乳製品の免疫科学的研究の展開2011
- Author(s)
  大谷元
- Journal Title
  
  ミルクサイエンス
  
  Volume: 60 Pages: 199-206
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] Effect of Lactobacillus pentosus ONRIC b0240 on intestinal IgA production in mice fed differing levels of protein2011
- Author(s)
  Shimosato T, Tomida K, Otani, H
- Journal Title
  
  Agriculture and Food Chemistry
  
  Volume: 59 Pages: 2646-2651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] The anti-allergic effects and acute toxicity of Lactobacillus crispatus KT-11 cultured in food grade medium2010
- Author(s)
  Tobita K, Yanaka H, Otani H
- Journal Title
  
  Journal of Agriculture and Food Chemistry
  
  Volume: 58 Pages: 6498-6502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] Anti-allergic effects of Lactobacillus crispatus KT-11 strain on ovalbumin-sentitized BALB/c mice2010
- Author(s)
  Tobita K, Yanaka H, Otani H
- Journal Title
  
  Animal Science Journal
  
  Volume: 81 Pages: 699-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580306
[Journal Article] The effect on mouse immune systems of cow's colostum produced 6 to 7 days after parturition2010
- Author(s)
  Y. OHASHI, K. UCHI DA, M. KAWASAKI, H. OTANI
- Journal Title
  
  Milc hwissenschaft 65
  
  Pages: 11-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] The effect on mouse immune systems of cow's colostum produced 6 to 7 days after parturition2010
- Author(s)
  Ohashi Y, Uchida, T, Kawasaki M, Otani H
- Journal Title
  
  Milchwissenschaft 65(1)
  
  Pages: 11-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Preparation of goat milk anti-Saccharomyces cerevisiae immunoglobulin G (IgG) -rich fraction and immunololgical functions of mice orally administered a mixture of the antigen and its specific IgG-rich fraction2009
- Author(s)
  Sekimura Y, Onodera N, Banno M, Hata I, Hamano K, Shimosato T, Otani H
- Journal Title
  
  Milk Science 58(3)
  
  Pages: 119-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Microassay analysis of mRNAs extracted from the Peyer's patch cells of mice given a diet including Escherichia coli and its specific bovine milk IgG2009
- Author(s)
  Sueda Y, Otani H
- Journal Title
  
  Milchwissenschaft 64(4)
  
  Pages: 354-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] The effect on mouse immune systems of cow's colostum produced 6 to 7 days after parturition2009
- Author(s)
  Ohash, Y, Uchida T, Kawasaki M, Otani H
- Journal Title
  
  Milchwissenschaft 64(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Microassay analysis of mRNAs extracted from the Peyer's patch cells of mice given a diet including Escherichia coli and its specific bovine milk IgG2009
- Author(s)
  Sueda Y, Otani H
- Journal Title
  
  Milchwissenschaft 64(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Preparation of goat milk anti-Saccharomyces cerevisiae immunoglobulin G(Ig G)-rich fraction and immunological functions of mice orally administered a mixture of the antigen and its specific IgG-rich fraction2009
- Author(s)
  Y. SEKIMURA, N. ONODERAa, M. BA NNO, I. HATA, K. HAMANO, T. SHIM OSATO, H. OTANI
- Journal Title
  
  Milk Science 58
  
  Pages: 119-128
- NAID
  130003398674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Microarray analysis of mRNAs extracted from the Peyer's patch cells of mice given a diet including Escherichia coli and its specific bovine milk IgG2009
- Author(s)
  Y. SU EDA, H. OTANI
- Journal Title
  
  Milchwissenschaft 64
  
  Pages: 354-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] チーズとホエイに含まれるたんぱく質の免疫科学2008
- Author(s)
  大谷元
- Journal Title
  
  New Food Industry 50(5)
  
  Pages: 45-58
- NAID
  40016023764
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] 牛乳タンパク質でアレルギーの予防とその症状を軽減する-牛乳タンパク質の特性を利用した試み(日本農学賞受賞記念論文)2008
- Author(s)
  大谷元
- Journal Title
  
  Biophilia 4(3)
  
  Pages: 41-48
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] 牛乳タンパク質でアレルギーの予防とその症状を軽減する-牛乳タンパク質の特性を利用した試み-2008
- Author(s)
  大谷元
- Journal Title
  
  Biophilia 4
  
  Pages: 43-50
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] 牛乳および乳製品において最近注目されている免疫調節機能とその解明技術2008
- Author(s)
  大谷元
- Journal Title
  
  乳業技術 58
  
  Pages: 51-68
- NAID
  40016583625
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] 牛乳たんぱく質の多様な機能-花粉症軽減食品への利用-2008
- Author(s)
  大谷元
- Journal Title
  
  北信越畜産学会新潟県分会報 43
  
  Pages: 9-14
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Immunomodulatory effects phosphorylated dextrin mouse spleen cell cultures2007
- Author(s)
  Otani, H., Sakakibara, I., Aoki, T.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 53(4)(印刷中)
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Oral ingestion of phosphorylated dextrin stimulates antibody responses in mice2007
- Author(s)
  Otani, H., Morimoto, T., Kawahara, T.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 53(4)(印刷中)
- NAID
  110006379688
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] A humoral immunoregulatory mechanism of bovine milk immunoglobulin G via Fcγreceptors in mice2007
- Author(s)
  H. OHNUKI, H. OTANI
- Journal Title
  
  Milchwissenschaft 62
  
  Pages: 450-453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] 新規機能性食品素材を用いた商品開発:牛乳蛋白質に秘められた多様な生体防御機能に基づき牛乳IgGを原料に用いた新規免疫調節食品開発の可能性2007
- Author(s)
  大谷元
- Journal Title
  
  食品工業
  
  Pages: 53-60
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Immunomodulatory effects of phosphorylated dextrin in mouse spleen cell cultures2007
- Author(s)
  Otani, H., Sakakibara, I., Aoki, T.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 53(4)(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Oral ingestion of phosphorylated dextrin stimulates antibody responses in mice2007
- Author(s)
  Otani, H., Morimoto, T., Kawahara, T.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 53(4)(in press)
- NAID
  110006379688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] A humoral immunoregulatory mechanism of bovine milk immunoglobulin G via Fcy receptors in mice2007
- Author(s)
  Ohnuki, H. and Otani, H.
- Journal Title
  
  Milchwissenschaft 62
  
  Pages: 450-453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580307
[Journal Article] Enhancement of immunoglobulin A formation by a casein phosphopeptide, β-casein(1-28), via modulation of cytokine produced by Th2 type of lymphocytes in mouse spleen cell cultures2006
- Author(s)
  Otani, H., Watanabe, T.
- Journal Title
  
  Milchwissenschaft 61(2)
  
  Pages: 123-126
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Enhancement of IgA formation by a casein phosphopeptide via modulation of cytokins produced by Th2 type of lymphocytes in mouse spleen cell cultures2006
- Author(s)
  Otani, H., Watanabe, T.
- Journal Title
  
  Milchwissenschaft 61(印刷中)
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Bovine β-casein (1-28), enhances proliferation and IL-6 expression of mouse CD19^+ cells via tool-like receptor-42006
- Author(s)
  Tobita, K., Kawahara, T., Otani, H
- Journal Title
  
  Journal of Agricultural and Food Chemistry 54
  
  Pages: 8013-8017
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Bovine β-casein (1-28), a casein phosphopeptide, enhances proliferation and IL-6 expression of mouse CD 19^+ cells via tool-like receptor-42006
- Author(s)
  Tobita, K., Kawahara, T., Otani, H.
- Journal Title
  
  Journal of Agricultural and Food Chemistry 54
  
  Pages: 8013-8017
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Enhancement of immunoglobulin A formation by a casein phosphopeptide, β-casein (1-28), via modulation of cytokine produced by Th2 type of lymphocytes in mouse spleen cell cultures2006
- Author(s)
  Otani, H., Watanabe, T.
- Journal Title
  
  Milchwissenschaft 61(2)
  
  Pages: 123-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Bovine β-casein (1-28), a casein phosphopeptide, enhances proliferation and IL-6 expression of mouse CD19+ cells via tool-like receptor-42006
- Author(s)
  Tobita, K., kawahara, T., Otani, H.
- Journal Title
  
  Journal of Agricultural and Fool Chemistry 54
  
  Pages: 8013-8017
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Appearance of antigen- and protein G-binding activities of orally administered cow's milk immunoglobulin G in mouse gastrointestinal tracts and feces2006
- Author(s)
  Ohnuki, H., Otani, H.
- Journal Title
  
  Milchwissenschaft 61(in press)
- Data Source
  KAKENHI-PROJECT-16658103
[Journal Article] Antigen- and protein G-binding abilities of immunoglobulin G in hyperimmunized cow's milk treated under various conditions2005
- Author(s)
  Ohnuki, H., Otani, H.
- Journal Title
  
  Animal Science Journal 76(3)
  
  Pages: 283-290
- Data Source
  KAKENHI-PROJECT-16658103
[Journal Article] Preparation of hypo-antigenic casein fragments having a stimulatory effect on IgA production in mouse spleen cell cultures2005
- Author(s)
  Zhang, F.M., Otani, H.
- Journal Title
  
  Milch wissenschaft 60(2)
  
  Pages: 175-179
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Antigen-and protein G-binding abilities of immunoglobulin G in hyperimmunized cow's milk treated under various conditions2005
- Author(s)
  Ohnuki, H., Otani, H.
- Journal Title
  
  Animal Science Journal 76(印刷中)
- Data Source
  KAKENHI-PROJECT-16658103
[Journal Article] Characterization of casein phosphopeptides from fermented milk products2005
- Author(s)
  Kawahara, T., Aruga, K., Otani, H.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 51(5)
  
  Pages: 377-381
- NAID
  10016770209
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Preparation of hypo-antigenic casein fragments having a stimulatory effect on IgA production in mouse spleen cell cultures2005
- Author(s)
  Zhang, F.M., Otani, H.
- Journal Title
  
  Milchwissenschaft 60(4)(印刷中)
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Characterization of casein phosphopeptides from fermented milk products2005
- Author(s)
  Kawahara, T., Aruga, K, Otani, H.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 51(5)
  
  Pages: 377-381
- NAID
  10016770209
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] 免疫調整と機能性食品〜スターリミルク2005
- Author(s)
  大谷元
- Journal Title
  
  機能性食品と薬理(日本機能性食品医用学会認定誌) 2(印刷中)
- Data Source
  KAKENHI-PROJECT-16658103
[Journal Article] 免疫調整と機能性食品〜スターリミルク2005
- Author(s)
  大谷元, 大貫秀隆, 畑勲
- Journal Title
  
  機能性食品と薬理(日本機能性食品医用学会認定誌) 2(4)
  
  Pages: 241-247
- Data Source
  KAKENHI-PROJECT-16658103
[Journal Article] Enhancement of IgA formation by a casein phosphopeptide via modulation of cytokins produced by Th2 type of lymphocytes in mouse spleen cell cultures2005
- Author(s)
  Otani, H., Watanabe, T.
- Journal Title
  
  Milchwissenschaft 60(印刷中)
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Preparation of hypo-antigenic casein fragments having a stimulatory effect on IgA production in mouse spleen cell cultures2005
- Author(s)
  Zhang, F.M., Otani, H.
- Journal Title
  
  Milchwissenschaft 60(2)
  
  Pages: 175-179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Preparation of hypo-antigenic casein fragments having a stimulatoryeffect on IgA production in mouse spleen cell cultures2005
- Author(s)
  Zhang, F.M., Otani, H.
- Journal Title
  
  Milchwissenschaft 60(2)
  
  Pages: 175-179
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Reduction of allergic symptoms in NC/Jic Jcl mice given a diet containing a commercially available casein phosphopeptide preparation2004
- Author(s)
  Otani, H., Wakatsuki, S.
- Journal Title
  
  Animal Science Journal 75
  
  Pages: 147-153
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Stimulatory effect of a casein phosphopeptide preparation on cytokine mRNA expression by human intestinal epithelical-like Caco-2 function2004
- Author(s)
  Kawahara, T., Otani, H.
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry 68
  
  Pages: 1779-1781
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Reduction of allergic symptoms in NC/Jic Jcl mice given a diet containing a commercially available casein phosphopeptide preparation, CPP-III2004
- Author(s)
  Otani, H., Wakatsuki, S.
- Journal Title
  
  Animal Science Journal 75
  
  Pages: 147-153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Effect of β-casein (1-28) on proliferative responses and secretory functions of human immunocompetent cell lines2004
- Author(s)
  Kawahara, T., Katayama, D., Otani, H.
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry 68
  
  Pages: 2091-2095
- NAID
  130000030949
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Effect of β-casein (1-28) on proliferative responses and secretory functions of human immunocompetent cell lines2004
- Author(s)
  Kawahara, T., Katayama, D., Otani, H.
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry 68(10)
  
  Pages: 2091-2095
- NAID
  130000030949
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Journal Article] Cow's IgG1 and its proteolytic digests stimulate immunoglobulin formations in mouse spleen cell cultures
- Author(s)
  Mizutani, A., Ohnuki, H., Kawahara, T., Otani, H.
- Journal Title
  
  Milchwissenschaft (Submitted)
- NAID
  120007106100
- Data Source
  KAKENHI-PROJECT-16658103
[Journal Article] Oral ingestion of cow's milk immunoglobulin G stimulates some cellular immune systems and suppresses humoral immunoresponses in mouse
- Author(s)
  Ohnuki, H., Otani, H.
- Journal Title
  
  International Journal of Immunopharmacology (Submitted)
- Data Source
  KAKENHI-PROJECT-16658103
[Patent] リン酸化糖アルコールを含んでなる免疫増強剤2006
- Inventor(s)
  大谷元, 砂川美和
- Industrial Property Rights Holder
  信州大, 王子製紙
- Industrial Property Number
  2006-221930
- Filing Date
  2006-08-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380180
[Patent] リン酸化澱粉糖を含んでなる細胞性免疫増強剤2006
- Inventor(s)
  大谷元, 砂田美和, 木村敏幸
- Industrial Property Rights Holder
  信州大学・王子製紙株式会社
- Industrial Property Number
  2007-019365
- Filing Date
  2006-08-16
- Data Source
  KAKENHI-PROJECT-16380180
[Patent] リン酸化糖アルコールを含んでなる免疫増強剤2006
- Inventor(s)
  大谷元, 砂田美和
- Industrial Property Rights Holder
  信州大学・王子製紙株式会社
- Industrial Property Number
  2006-221930
- Filing Date
  2006-08-16
- Data Source
  KAKENHI-PROJECT-16380180
[Presentation] ウシ後期初乳の抗腫瘍作用に関する検討2013
- Author(s)
  長谷川実希,内田健志,川西貴,下里剛士,大谷元
- Organizer
  第116回日本畜産学会大会
- Place of Presentation
  広島
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ウシ後期初乳の新規生体防御機能の探索2012
- Author(s)
  長谷川実希,遠見和幸,内田健志,川西貴,下里剛士,大谷元
- Organizer
  第115回日本畜産学会大会
- Place of Presentation
  名古屋
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ウシ後期初乳中の抗アレルギータンパク質の探索2012
- Author(s)
  遠見和幸,須賀正喜,内田健志,川西貴,下里剛士,大谷元
- Organizer
  第115回日本畜産学会大会
- Place of Presentation
  名古屋
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ビール酵母とその牛乳抗体のマウスI型アレルギーに及ぼす影響2012
- Author(s)
  森崎健太郎, 松田孝裕, 岡田実, 堀江健二, 金武祚, 下里剛士, 大谷元
- Organizer
  第115回日本畜産学会大会
- Place of Presentation
  名古屋大学(名古屋市)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ウシ後期初乳中の抗アレルギータンパク質の探索2012
- Author(s)
  遠見和幸, 須賀正喜, 内田健志, 為定誠, 下里剛士, 大谷元
- Organizer
  第115回日本畜産学会大会
- Place of Presentation
  名古屋大学(名古屋市)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ビール酵母とその牛乳抗体のマウス I 型アレルギーに及ぼす影響2012
- Author(s)
  森崎健太郎,松田孝裕,岡田実,堀江健二,金武祚,下里剛士, 大谷元
- Organizer
  第115回日本畜産学会大会
- Place of Presentation
  名古屋
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ミルク成分の免疫科学的研究の展開2011
- Author(s)
  大谷元
- Organizer
  日本酪農科学会創立 60 周年記念シンポジウム(招待講演)
- Place of Presentation
  仙台
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ウシ後期初乳および常乳のマウスI型アレルギーに及ぼす影響2011
- Author(s)
  遠見和幸,清水努,内田健志,為定誠,下里剛士, 大谷元
- Organizer
  第114回日本畜産学会大会
- Place of Presentation
  十和田
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] 牛乳タンパク質とその消化により生じるペプチドの免疫調節機能の特性付けと利用性2011
- Author(s)
  大谷元
- Organizer
  日本農芸化学会東北支部シンポジウム(招待講演)
- Place of Presentation
  弘前
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ウシ後期初乳および常乳のマウスI型アレルギーに及ぼす影響2011
- Author(s)
  遠見和幸, 清水努, 内田健志, 為定誠, 下里剛士, 大谷元
- Organizer
  第114回日本畜産学会大会
- Place of Presentation
  北里大学(青森県十和田市)
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] ビール酵母とその牛乳IgGの1型アレルギーに及ぼす影響2011
- Author(s)
  森崎健太郎・松田孝裕・下里剛士・大谷元
- Organizer
  第113回日本畜産学会大会
- Place of Presentation
  神奈川
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22580306
[Presentation] 牛乳蛋白質の免疫調節機能の探索とその利用性2010
- Author(s)
  大谷元
- Organizer
  日本畜産学会主催シンポジウム"ルミナントバイオロジーの新展開"乳・肉の機能因子の発見と実用の展望
- Place of Presentation
  明治大学駿河台校キャンパスリバティーホール (東京)
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-19580307
[Presentation] パン酵母とそれを認識したシバヤギ乳IgG分画を摂取した健常マウスの免疫系2008
- Author(s)
  小野寺尚・末田木綿・大谷元
- Organizer
  日本畜産学会第109回大会
- Place of Presentation
  常盤大学
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19580307
[Presentation] パン酵母とそれに対するヤギ乳IgGを添加した飼料で飼育したマウスの免疫系2008
- Author(s)
  関村有美, 小野寺尚, 大谷元
- Organizer
  平成20年度日本酪農科学シンポジウム
- Place of Presentation
  武蔵野スイングホール
- Year and Date
  2008-08-29
- Data Source
  KAKENHI-PROJECT-19580307
[Presentation] パン酵母とヤギ乳IgGを摂取したNC/NがTndCrljマウスのアレルギー症状2008
- Author(s)
  関村有美・濱野光市・大谷元
- Organizer
  日本畜産学会第109回大会
- Place of Presentation
  常盤大学
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19580307
[Presentation] 腸管におけるIgGの役割は免疫系の調節?牛乳IgG・抗原複合体は多様なメカニズムで液性免疫応答を抑制する2007
- Author(s)
  末田木綿・大谷元
- Organizer
  平成19年度日本酪農科学会シンポジウム
- Place of Presentation
  岐阜市ホテルグランベヴエル岐山
- Year and Date
  2007-08-24
- Data Source
  KAKENHI-PROJECT-19580307

1. HOSONO Akiyoshi (20021074)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KAWAHARA Takeshi (30345764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. ITOH Takatoshi (80005610)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KATAOKA Kei (90032987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMANAKA Yoshitada (80078112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. WATANABE Kenji (70023447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIROTA Mitsuru (90199133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAMO Tunashi (60345759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ADACHI Susumu (10005580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIYAMOTO Taku (00093708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAE Toshitaka (40032974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 古川徳 (10078149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OTANI Hajime 大谷 元

Research Projects

Research Products

Co-Researchers

Studies on anti-allergic properties of a mixture of Saccaromyces pastorianus and its specific cow's milk antibodyPrincipal Investigator

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Elucidation of active immunomodulatory function of milk IgG and development of its utilityPrincipal Investigator

Principal Investigator

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ウシIgGの新規免疫調節食品素材としての利用面の探索Principal Investigator

Principal Investigator

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Development of a functional feed on the basis of immunostimulatory action of casein phosphopeptidePrincipal Investigator

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Development of non-allergic peptide preparation having mucosal immunostimulatory abilityPrincipal Investigator

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Elucidation of immnoregulating function of casein phosphopeptidePrincipal Investigator

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Immunosuppresive action of milk k-casein and its digestsPrincipal Investigator

Principal Investigator

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Studies on the immuno-modulating ability of bovine milk and avian eggsPrincipal Investigator

Principal Investigator

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化学修飾による鶏卵黄抗体の機能改善Principal Investigator

Principal Investigator

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特異抗体の分離源としての鶏卵利用Principal Investigator

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Studies on Antimutagenic and Antitumoral Activities of Microbial Polysaccharides

Principal Investigator

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発酵乳スターター菌体成分の抗変異原性

Principal Investigator

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Research Institution

Studies on anti-carcinogenic activity of fermented milk and its application

Principal Investigator

Project Period (FY)

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OTANI Hajime 大谷元

[Book] 畜産学入門(唐澤豊・大谷元・菅原邦生編)2012