AKIGUCHI Ichiro 秋口一郎

… Alternative Names

秋口一郎アキグチイチロウ

AKIGCHI Ichiro 秋口一郎

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Researcher Number	30115779
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 滋賀医科大学, 医学部, 客員教授 2002 – 2005: 龍谷大学, 健康管理センター, センター長 2004: Ryukoku University, Department of Health Control, Director, 健康管理センター, 所長 1995 – 2000: 京都大学, 医学研究科, 助教授 1997: 京都大学, 医学研究所, 助教授 … More 1991 – 1994: 京都大学, 医学部, 助教授 1990: 京都大学, 医学部, 講師 1988: 京都大学, 医学部, 講師 Less
Review Section/Research Field	Except Principal Investigator Neurology / Experimental pathology / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Neurology / Neuroscience in general
Keywords	Principal Investigator 海馬 / 神経細胞死 / フリーラジカル / アストログリア / 脳虚血 / TRX / ADF / 遅発神経細胞壊死 / アイソザイム / 情報伝達機構 … More / 神経難病 / 遅発神経細胞懐死 / Western blot / Immunohistochemistry / 一過性全脳虚血 / ATL-derived factor / ムスカリン受容体 / アセチルコリン / ニコチン受容体 / BDNF / 神経成長因子(NGF) / NMDA受容体 / グルタミン酸 / トランスロケーション / プロテインキナーゼC / 内嗅皮質 / 実験神経学 / プロテインキナ-ゼC / 中隔野 … More Except Principal Investigator ALS / fasciculation / GDNF / 免疫組織化学 / パーキンソン病 / α-synuclein / COX-2 / immunohistochemistry / 筋萎縮性側索硬化症 / ニューロパチー / K channel / 多系統萎縮症 / HAM / HTLV-I / Lewy body / Parkinson's disease / K^+ channel / グルタミン酸 / Multifocal Motor Neuropathy / PSTH / Lewy小体 / αシヌクレイン / H5 / Septin / GDNFR / Glial cell line-derived neurotrophic factor / ポリニューロパチー / 末梢神経 / BDNF / 細胞障害性T細胞 / Fasciculation / dystonia / central motor program / familial / multifocal motor neuropathy / Brain atrophy / Deficits in learning & memory / Senescence / Animal model / Senescence-Accelerated Mouse (SAM) / 脳萎縮 / 学習・記憶障害 / 老化 / 老年期脳障害モデル / 老化促進モデルマウス / magnetic stimulation / motor neuron disease / K^+チャネル / 大脳磁気刺激法 / TE法 / 認知症予防 / 脳卒中予防 / 認知症 / 脳梗塞 / 水分摂取 / 認知機能 / 水分摂取習慣 / 脳梗塞予防 / molecular chaperones / astrocytes / Lewy body-like hyaline inclusins / glial cytoplsmic inclusions / Lewy bodies / 14-3-3 proteins / 脱髄疾患 / リン酸化タウ / 免疫組織化学法 / クロイツフェルト・ヤコブ病 / 分子シャペロン / アストロサイト / Lewy小体様硝子様封入体 / グリア細胞質内封入体 / 14-3-3蛋白 / Glial cytoplasmic inclusion(GCI) / αsynuclein / Proteasome / Synphilin / ubiquitin / sepin / 黒質 / glial cytoplasmic inclusion(GCI) / septin / glial cytoplasmic inclusion (GCI) / プロテアゾーム / synphilin-1 / neuregulin / Schwann cell / neuritis / COX-2 inhibitor / treatment / polyneuropathy / neuropathy / アポトーシス / COX-2 インヒビター / ギラン・バレー症候群 / 神経再生 / 軸索変性 / CIDP / 末梢神経障害 / ニューレグリン / シュワン細胞 / 神経周膜炎 / 多発神経炎 / amyotrophic lateral sclerosis / persephin / パーセフィン / rat brain / GDNF-receptor / 神経変性疾患 / 抗GDNFR抗体 / グリア細胞由来神経栄養因子受容体 / Immunohistochemistry / neurodegenerative disease / GFRα1 / GDNF receptor / TNF-alpha / macrophage / T cell / Polyneuropathy / Peripheral nerve / 脱髄 / TNF-α / マクロファージ / T細胞 / rat / neurotrophci factor / ラット脳 / ラット / 神経栄養因子 / glutamate / Magnetic Brain Stimulation / Threshold Electrotonus / threshald electrotonus / methylcobalamin / Multifocal Motor Meuropathy / monkey / MEP / EMG / animal study / safety / high freguency stimulator / Repetitive stimulator / Magnetic stimulation / 有用性 / 変動磁場 / 連続磁気刺激 / 高頻度磁気刺激 / 日本猿 / 運動誘発電位 / 筋電図 / 動物実験 / 安全性 / 高頻度磁気刺激装置 / 連続磁気刺激装置 / 磁気刺激 / discharge probability / リルゾール / シナプトフィジン / ジストニア / CNV / 大脳磁気刺激 / 発火確率 / Kチャンネル / ジストニ- / 中枢運動プログラム / 家族性 / 変換不可 / Indeterminate / Cytotoxic T lymphocyte / Polymerase chain reaction / Western blot / CTL / ウェスタンブロッド法 / indeterminate / PCR法 / ウェスタンブロット法 / Discharge prohability / Dystonia / Central motor program / Familial / Multifocal motor neuropathy / アクリルアミド / ビタミンB_<12> / 血液神経関門 / 一側性上肢筋萎縮症 / MMN / central motor prosran / multitocal motor neuropathy / discharge prohability / fascicalation / Monoamine oxidase / Multiple system atrophy / Alzheimer's disease / Tuberomammillary nucleus / Hypothalamus / Human / Histamine / モノアミン酸化酵素 / Tuberomamillary nucleus / アルツハイマー病 / 視床下部 / ヒト / ヒスタミン / Fatty acid / Reticular formation / 大脳新皮質 / 脳幹網様体 / 血液・脳バリア / 食餌脂肪酸 / 脂肢酸 / 脂肪酸 / 網様体 / モデル動物開発 / プロウイルスDNAクローニング / レトロウイルス構造 / 多発性硬化症 / HTLV-I関連脊髄症 / neurofilament protein / p39 / p35 / threonine kinase / serine / Cdk5 / Cyclin-dependent kinae5 / threshad electrotonus / methylc : balamin / CDK5 / CDC2 / サイクリン依存性キナーゼ / 細胞周期 / プロテインキナーゼ / シナプス / 神経筋接合部 Less

Impact of Hydration Habits on Stroke Recurrence and Cognitive Decline: An Observational Study Including Imaging Evaluation
- Principal Investigator
  
  Nishikawa Tomofumi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Kyoto Koka Women's University
the role of molecular chaperones in α-synuclein-related diseases
- Principal Investigator
  
  KAWAMOTO Yasuhiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
significance of septin in the formation of inclusion bodies in neurodegenerative disorders.
- Principal Investigator
  
  TOMIMOTO Hidekazu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
The molecular pathological study on the persephin in neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  AKIGUCHI Ichiro, 中村慎一
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVESITY
Development of a new treatment for peripheral neuropathies
- Principal Investigator
  
  OKA Nobuyuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  HYOGO COLLEGE OF MEDICINE
  Kyoto University
サイクリン依存性キナーゼ5とパーキンソン病脳神経細胞死に関する分子病理学的研究
- Principal Investigator
  
  中村慎一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Localization of glial-cell line derived neurotrophic factor receptor (GFRa1) in the brain
- Principal Investigator
  
  NAKAMURA Shinichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVERSITY
ADF(ATL由来因子)/チオレドキシンの脳内発現と神経細胞死‐ラジカル消去作用と虚血脳保護効果‐Principal Investigator
- Principal Investigator
  
  秋口一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Cytotoxic mechanisms of T-lymphocytes in peripheral neuropathy
- Principal Investigator
  
  OKA Nobuyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVERSITY
ADF(ATL由来因子)/チオドレキシンの脳内発現と神経細胞死-急性および慢性虚血脳での脳保護作用-Principal Investigator
- Principal Investigator
  
  秋口一郎
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
神経・節シナプス形成,消失における細胞周期関連蛋白
- Principal Investigator
  
  OKA Nobuyuki
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
筋萎縮性側索硬化症と治療に関する研究
- Principal Investigator
  
  KIMURA Jun
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
A study on the pathophysiology of ALS with therapeutic implications.
- Principal Investigator
  
  KIMURA Jun
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY
Immunohistochemcial investigation of brain-derived neurotrophic factor in the human brain
- Principal Investigator
  
  NAKAMURA Shinichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVERSITY
ADF(ATL由来因子)/チオレドキシンの脳内発現と神経細胞死;急性および慢性虚血脳での脳保護作用Principal Investigator
- Principal Investigator
  
  秋口一郎
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Trial manufacture of high freguency repetitive magnetic stimuletor : stability, safety and clinical usefulness
- Principal Investigator
  
  KIMURA Jun
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  KYOTO UNIVERSITY
神経難病における神経細胞死と情報伝達機構異常Principal Investigator
- Principal Investigator
  
  秋口一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Multi-disciplinary Approach of Pathophysiology of ALS
- Principal Investigator
  
  KIMURA Jun
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
神経難病における神経細胞死と情報伝達機構異常Principal Investigator
- Principal Investigator
  
  秋口一郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
A Study on Pathophysiology of Amyotrophic Lateral Sclerosis (ALS)
- Principal Investigator
  
  KIMURA Jun
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVERSITY
Molecular epidemiology of HTLV-I seroindeterminate myelopathy
- Principal Investigator
  
  KAWANISHI Taketo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVERSITY
神経難病における神経細胞死と情報伝連機構異常Principal Investigator
- Principal Investigator
  
  秋口一郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Comprehensive studies on age-related deficits in learning and memory in SAM
- Principal Investigator
  
  TAKEDA Toshio
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
The central histminergic system in normal controls and patients with neurodegenerative disorders
- Principal Investigator
  
  NAKAMURA Shinichi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KYOTO UNIVERSITY
Development of murine models for aging brain, Senescence-Accelerated Mouse (SAM)
- Principal Investigator
  
  TAKEDA Toshio
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  KYOTO UNIVERSITY
ヒト神経疾患の発症に関与するレトロウイルスの検索
- Principal Investigator
  
  前田道之
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University

All 2004 Other

All Journal Article Other

[Journal Article] Topographical and cytopathological lesion analysis of the white matter of Binswanger's disease brains2004
- Author(s)
  Akiguchi et al.
- Journal Title
  
  Acta Neuropathologica 107
  
  Pages: 563-570
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590887
[Journal Article] Topographical and cytopathological lesion analysis of the white matter in Binswanger's disease brains.2004
- Author(s)
  Akiguchi I, Tomimoto H et al.
- Journal Title
  
  Acta Neuropathol (Berl) 107, 6
  
  Pages: 563-570
- Data Source
  KAKENHI-PROJECT-14570592
[Journal Article] Topographical and cytopathologic lesion analysis of the white matter of Binswanger's disease brains2004
- Author(s)
  I.Akiguchi et al.
- Journal Title
  
  Acta Neuropatholica 107
  
  Pages: 563-570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590887
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1. NAKAMURA Shinichi (20231475)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. KIMURA Jun (10204976)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. KAJI Ryuji (00214304)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. SHIMOHAMA Shun (60235687)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. OKA Nobuyuki (90252444)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. FUKUYAMA Hidenao (90181297)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SHIBASAKI Hiroshi (30037444)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. TAKEDA Toshio (00027088)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HIGUCHI Keiichi (20173156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. HOSOKAWA Masanori (00127135)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KOHARA Nobuo (20252439)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. EISEN Andrew

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. DAUBE Jasper

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KAWANISHI Taketo (40240824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TOMIMOTO Hidekazu (80324648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. NODA Makoto (30146708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KITAYAMA Hitoshi (30231286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KAWAMOTO Yasuhiro (40335253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Nishikawa Tomofumi (20647945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 前田道之 (20027329)

# of Collaborated Projects: 1 results

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21. 石本秋稔 (50073127)

# of Collaborated Projects: 1 results

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22. 萬年徹 (10010208)

# of Collaborated Projects: 1 results

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23. 岡村智教 (00324567)

# of Collaborated Projects: 1 results

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24. 福田俊一 (10600546)

# of Collaborated Projects: 1 results

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25. 志摩梓 (20635958)

# of Collaborated Projects: 1 results

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26. 北条雅人 (60372588)

# of Collaborated Projects: 1 results

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27. 宮松直美 (90314145)

# of Collaborated Projects: 1 results

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28. 杉山大典 (90457052)

# of Collaborated Projects: 1 results

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29. 金丸恭子 (40908290)

# of Collaborated Projects: 1 results

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30. MIYAMOTO Masaomi

# of Collaborated Projects: 1 results

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31. YARITA Masaru

# of Collaborated Projects: 1 results

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32. GRAFE Peter

# of Collaborated Projects: 1 results

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33. BOSTOCK Hugh

# of Collaborated Projects: 1 results

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34. QUASTHOFF Stephen

# of Collaborated Projects: 1 results

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35. CORNBLATH David

# of Collaborated Projects: 1 results

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36. ENGLAN John

# of Collaborated Projects: 1 results

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37. SUMMER Austin

# of Collaborated Projects: 1 results

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38. ROWLAND Lewis

# of Collaborated Projects: 1 results

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39. MURRAY Nicholas

# of Collaborated Projects: 1 results

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40. 松尾隆夫

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 水谷江太郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. DAUBE J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. MILLS K.

# of Collaborated Projects: 1 results

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44. EISEN A.

# of Collaborated Projects: 1 results

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45. MILLS Kerry

# of Collaborated Projects: 1 results

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46. SEITERBERGER

# of Collaborated Projects: 1 results

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47. JOHN C ROTHW

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. ASAO HIRANO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. ANDREW EISEN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 槍田勝

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. BURKE David

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. ROTHWEV John

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AKIGUCHI Ichiro 秋口 一郎

秋口 一郎 アキグチ イチロウ

AKIGCHI Ichiro 秋口 一郎

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The molecular pathological study on the persephin in neurodegenerative diseasesPrincipal Investigator

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ADF(ATL由来因子)/チオドレキシンの脳内発現と神経細胞死-急性および慢性虚血脳での脳保護作用-Principal Investigator

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AKIGUCHI Ichiro 秋口一郎

秋口一郎アキグチイチロウ

AKIGCHI Ichiro 秋口一郎