WATANABE Akihiko 渡辺昭彦

Researcher Number	30126263
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2008: Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Assistant Professor 1999 – 2006: Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 生体材料工学研究所, 助手 1997 – 1998: 東京医科歯科大学, 医用器材研究所, 助手 1996: 医用器材研究所, 有機材料部門, 助手 1996: Tokyo Medical and Dental University, Institute for Medical and Dental Engineerin, 医用器材研究所・有機材料部門, 助手 … More
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Conservative dentistry Except Principal Investigator Biomedical engineering/Biological material science / Conservative dentistry / Biological Sciences / Biomedical engineering/Biological material science / Science and Engineering / 補綴理工系歯学 / 補綴理工系歯学
Keywords	Principal Investigator MPC共重合体 / 生体適合性 / 細胞培養 / たんぱく質吸着 / Ne イオン照射 / サイトカイン産生 / Neイオン照射 / 医用ポリマー / MPCポリマー / 傾斜細胞応答性材料 … More Except Principal Investigator 接着 / ハイドロキシアパタイト / ナノゲル / 象牙質 / 樹脂含浸象牙質 / 生体適合性 / 医用材料 / 分子シャペロン / 4-META / リン脂質ポリマー / 血小板粘着 / タンパク質吸着 / 硬組織 / 歯質 / 含浸層 / 歯科用材料 / コラーゲン / メタクリレート / 疎水化多糖 / サイトカイン / Dentin / 歯科材料 / 血液適合性 / タンパク質 / 重合 / 複合化 / 生体組織 / 人工分子シャペロン / 癌免疫 / 歯科用接着剤 / 反応性 / 反応性高分子 / Dental Adhesive / Bonding / MMA-TBBレジン / Biocompatibility / 抗血栓性 / Nonthrombogenicity / Protein adsorption / Hybridized Dentin / 自己組織化 / 歯質接着性レジン / リン脂質 / 生体膜構造 / 2ーメタクリロイルオキシエチルホスホリルコリン / 組織化吸着 / 血小板 / 4ーメタクリロイルオキシエチルトリメリット酸無水物 / EDTA / ハイブリッド / 機能性モノマ- / ボ-ンセメント / 機能性モノマー / 可視光線 / 分子シンクロ / スピロピラン / リフォールディング / シクロデキストリン / タンパク質のリフォールディング / DNAの二重鎖形成 / 癌免疫療法 / インターロイキン12(IL12) / 分子シャペロン機能 / ドラッグデリバリーシステム / 腫瘍抑制 / 徐放 / インターロイキン12 / DDS / 癌抗原 / 癌タンパク質ワクチン / 癌免疫治療 / IL12 / 遺伝子デリバリー / カチオン性多糖 / タンパク質ワクチン / トランスフェクション / サイトカン / 潰伝子デリバリー / 高分子 / グラフト共重合体 / キレ-ト結合 / 歯科接着材 / 高分子電解質 / pースチレンスルホン酸 / エナメル質 / 歯科用レジン / Polymer / Reactivity / Graft Copolymer / Hydroxyapatite / Chelate Bond / 含浸 / モノマー / 安定性 / 歯科接着剤 / 浸透性 / ハイブリッド層 / モノマ- / メタクリレ-ト / Interpenetration / Monomer / Hybrid Layer / Methacrylate / 生体材料 / 樹脂含浸層 / Biomaterials / Dental materials / Hybrid layr / MMA / TBB resin / 高分子エマルション / 知覚過敏象牙質 / MMA-スチレンスルホン酸ポリマー / 析出 / ラテックス / 知覚過敏症 / ポリスチレンスルホン酸 / 被膜形成 / DENTAL MMTERIALS / REACTIVE POLYMER / POLYMER EMULSION / HYPERSENSITIVE DENTIN / MMA-STYRENESULFONATECO POLYMER / DEPOSITION / 血液透析膜 / 補体活性化 / 人工腎臓 / 血液透析 / 補体活性 / 表面修飾 / Hemodialysis Membrane / Hemocompatibility / Phospholipid Polymer / Platelet Adhesion / Protein Adsorption / Complement Activation / Artificail Kidney / 医用料材 / 高分子添加材 / ゼグメント化ポリウレタン / セグメント化ポリウレタン / Biomaterial / Phospholipid polymer / Polymeric additive / Segmented polyurethane / Platelet adhesion / 接着レジン / 引張り試験 / ダンベル型試料 / 接着性レジン / Dental Materials / adhesive resin cements / Tensile Test / Dumbbell-Shaped specimens / Adhesion / Medical Materials / 生体膜類似構造 / 医用ポリマー / MPCポリマー / 自由水 / 表面 / 材料化学的特性 / リン脂質極性基 / 血小板の機能 / 生体適合性ポリマー / 細胞粘着 / BIOMEMBRANE-LIKE STRACTURE / BIOMEDICAL POLYMER / BLOOD COMPATIBILITY / MPC POLYMER / PLATELET ADHESION / PROTEIN ADSORPTION / FREE WATER / SURFACE / ウェットボンディング / 象牙質への接着 / 引張試験 / ダンベル型 / Dentin bonding / Hybridized dentin / Wet-bonding / Adhesion to dentin / Tensile test / Dumbbell / 人工エナメル質 / モノマー透過性 / ミニダンベル型引張試験 / アセトンプライマー / スミヤー層 / リン酸エッチング / 人工エナメル / マイクロリーケージ / 耐酸性 / Artificial Enamel / Encapusulated Hydroxyapatite / Enveloped collagen / MMA-TBB resin / 血液・輸液バック / ポリオレフィン / 光重合法 / 表面改質 / 光重合 / MPC / ポリエチレンフイルム / SEM / 血小板粘着抑制効果 / Blood Bag / Polyorefine / Phosoholipid polymer / Blood compatibility / Platelet adhension / Photo-induced polymerization / Surface modification / 会合性高分子 / 刺激応答性 / タンパク質フォールディング / 細胞外タンパク質合成 / Nanogel / Associated polymer / Self-assembly / Hydrophobized polysaccharides / Stimuli-responsive / Artificial molecular chaperone / Protein folding / ヒドロゲル / 量子ドット / アパタイト / 生分解性 / リポソーム / nanogels / hydrogel / hydrophobized polysacchardes / quantum dot / apatite / molecular chaperone / 要介護者 / 高齢者 / レジン床義歯 / 義歯粘膜側軟質レジン層 / EHMA-MMA共重合体 / 軟らかさ / 緩和応力速度 / 圧縮後寸法回復率 / 軟らかさ係数 / 硬質 / 軟質レジン複合化構造 / 軟質レジン / 圧縮特性 / 引張特性 / 義歯床下粘膜 / 軟質レジン複合化床義歯 / elderly person in need of care / resin based denture / soft lining on mucous membrane side / EHMA-MMA copolymer / softness / relaxation stress rate / ratio of dimensional recovery after compression / viscoelasticity Less

Development of nanocarrier for cancer immunotherapy
- Principal Investigator
  
  AKIYOSHI Kazunari
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
癌免疫治療のための新規ナノゲルキャリアの開発
- Principal Investigator
  
  秋吉一成
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
分子シャペロン機能を有するナノゲルキャリアによる新規DDSの開発
- Principal Investigator
  
  秋吉一成
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Design of hybrid hydrogels by nanogel engineering for biomaterials
- Principal Investigator
  
  AKIYOSHI Kazunari
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Medical and Dental University
Studies on the development of new soft resin-based denture for elderly person in need of care
- Principal Investigator
  
  NAGAI Masahiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Tokyo Medical and Dental University
Design of bio-nanosystem by dynamic control of nanoorganization
- Principal Investigator
  
  AKIYOSHI Kazunari
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Medical and Dental University
シャペロニング機能を有する分子シンクロシステムの構築
- Principal Investigator
  
  AKIYOSHI Kazunari
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Medical and Dental University
  Kyoto University
Developing and clinical application of a highly reliable dentin-bonding system.Principal Investigator
- Principal Investigator
  
  WATANABE Akihiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Tokyo Medical and Dental University
Preparation of non-biofouling blood bags
- Principal Investigator
  
  IWASAKI Yasuhiko, 中林宣男
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Medical and Dental University
Artificial Enamel : Preparation and Evaluation.
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Conservative dentistry
- Research Institution
  Tokyo Medical and Dental University
脂質とポリマーとの傾斜機能型分子複合体の合成と接着機構の解明
- Principal Investigator
  
  中林宣男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
PREPARATION OF NOVEL BIOMEDICAL POLYMERS HAUING BIOMEMBRANE-LIKE SURFACE AND RECOGNITION OF THEIR NON THROMBOGENIC
- Principal Investigator
  
  ISHIHARA Kazuhiko
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  THE UNIVERSITY OF TOKYO
  Tokyo Medical and Dental University
Long-durable bonding of resin to dentin
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Tokyo Medical and Dental University
Excellent biocompatibility of MPC polymers as biomaterials evaluated by fibroblast and HL-60 cells.Principal Investigator
- Principal Investigator
  
  WATANABE Akihiko
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Medical and Dental University
Effect of Miniaturized Dumbbell-Shaped Specimen to Identify Bonding of Bovine Dentin
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Tokyo Medical and Dental University
Preparation of Novel Biocompatible polymeric Additives and Modification of Biomedical Materials Using the Additives
- Principal Investigator
  
  ISHIHARA Kazuhiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Medical and Dental University
DEVELOPMENT OF TREATMENT AGENT FOR HYPERSENSITIVE DENTIN BY DENTINE ADHESIVE POLYMERIC LATEX
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  INSTUTE FOR MEDICAL AND DENTAL ENGINEERING,TOKYO MEDICAL AND DENTAL UNIVERSITY
PREPARATION OF NONTOROMBOGENICHEMODIALYZER AND ITS PRECLINICAL EVALUATION
- Principal Investigator
  
  ISHIHARA Kazuhiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  INSTITUTE FORR MEDICAL AND DENTAL ENGINEERING,TOKYO MEDICAL AND DENTAL UNIVERSITY
Hybridization and functionalization of biocompatible monomer by in situ polymerization in teeth.
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Medical and Dental University
硬組織親和性モノマーを活用した生体組織とのハイブリッド化ならびにその耐久性
- Principal Investigator
  
  中林宣男
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
骨・歯適合性モノマ-の硬組織内重合による複合化と機能評価
- Principal Investigator
  
  中林宣男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
Development of New Dental Adhesives
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tokyo Medical and Dental University
生体成分を組織化吸着するポリマ-の合成と細胞機能制御に関する研究
- Principal Investigator
  
  ISHIHARA Kazuhiko
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
硬組織親和性ポリマ-を用いる組織の複合化と機能強化
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
Preparation and Pre-Clincal Evaluation of Novel Polymeric Dental Adhesives with Excellent Safty
- Principal Investigator
  
  NAKABAYASHI Nobuo
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Tokyo Medical and Dental university

All 2007 2006

All Presentation

[Presentation] 高齢者用レジン床義歯の開発、市販軟質裏装材とEHMA-MMA共重合体の力学的特性2007
- Author(s)
  石綿勝、永井正洋、門磨義則、渡辺昭彦、三浦宏之、高久田和夫
- Organizer
  日本歯科技工学会
- Place of Presentation
  仙台
- Year and Date
  2007-09-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] 高齢者用レジン床義歯の開発-市販軟質裏装材とEHMA-MMA共重合体の軟らかさ係数、緩和応力速度および圧縮後寸法回復率2007
- Author(s)
  永井正洋、門磨義則、渡辺昭彦、石綿勝、宮入裕夫、高久田和夫
- Organizer
  日本歯科理工学会
- Place of Presentation
  札幌
- Year and Date
  2007-05-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] Development of the resin-based denture for elderly person : Mechanical properties of the commercially available soft liner and EHMA-MMA copolymers2007
- Author(s)
  M. TSHIWATA, M. NAGAI, Y. KADOMA, A. WATANABE, K. TSUCHIHIRA and H. MIURA and K. TAKAKUDA
- Organizer
  29th Nippon Academy of Dental Technology
- Place of Presentation
  Sendai
- Year and Date
  2007-09-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] 高齢者用レジン床義歯の開発-軟質裏装材の力学的特性2007
- Author(s)
  永井正洋、門磨義則、渡辺昭彦、石綿勝、塩田一路、高久田和夫
- Organizer
  日本材料科学会
- Place of Presentation
  東京
- Year and Date
  2007-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] Development of the resin-based denture for elderly person : modulus of softness, relaxation stress rate and ratio of dimensional recovery of the commercially available tissue conditioners and EHMA-MMA copolymers2007
- Author(s)
  M. NAGAI, Y. KADOMA, A. WATANABE, M. ISHIWATA, H. MIYAIRI and K. TAKAKUDA
- Organizer
  The 49th General Session of the Japanese Society for Dental Materials and Devices
- Place of Presentation
  Sapporo
- Year and Date
  2007-05-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] Development of soft and flexible resin base denture for elderly persons : Softness and Stress relaxation of EHMA-MMA copolymers2006
- Author(s)
  M. NAGAI, Y. KADOMA, Y. KONDO, A. WATANABE, M. ISHIWATA and K. TAKAKUDA
- Organizer
  The 48th General Session of the Japanese Society for Dental Materials and Devices
- Place of Presentation
  Nagoya
- Year and Date
  2006-10-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] Development of soft and flexible resin base denture for elderly persons : Mechanical properties of EHMA-MMA copolymers2006
- Author(s)
  M. NAGAI, Y. KADOMA, Y. KONDO, A. WATANABE, M. ISHIWATA and K. TAKAKUDA
- Organizer
  The 47th General Session of the Japanese Society for Dental Materials and Devices
- Place of Presentation
  Tokyo
- Year and Date
  2006-04-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] 高齢者用軟質レジン床義歯の開発-軟質レジン:2チエルヘキシルメタクリレート(EHMA)-メチルメタクリレート(MMA)共重合体の軟らかさおよび応力緩和2006
- Author(s)
  永井正洋、門磨義則、近藤雄飛、渡辺昭彦、石綿勝、高久田和夫
- Organizer
  日本歯科理工学会
- Place of Presentation
  名古屋
- Year and Date
  2006-10-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592017
[Presentation] 高齢者用軟質レジン床義歯の開発、軟質レジン:2エチルヘキシルメタクリレート(EHMA)-メチルメタクリレート(MMA)共重合体の力学的特性2006
- Author(s)
  永井正洋、門磨義則、近藤雄飛、渡辺昭彦、石綿勝、高久田和夫
- Organizer
  日本歯科理工学会
- Place of Presentation
  東京
- Year and Date
  2006-04-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592017

1. NAKABAYASHI Nobuo (30014020)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
2. ISHIHARA Kazuhiko (90193341)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
3. IWASAKI Yasuhiko (90280990)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
4. MORIMOTO Nobuyuki (00313263)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
5. AKIYOSHI Kazunari (90201285)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
6. TANAKA Shinobu (40242218)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. 松田修 (00271164)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 澤田晋一 (50444104)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. FUJII Benji (00066979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AKIZAWA Tadao (40102339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGAI Masahiro (10013971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
12. TAKAKUDA Kazuo (70108223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. KADOMA Yoshinori (00092403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
14. KOYAMA Yoshiisa (70361714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ISHIWATA Masaru (70292985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
16. 野村慎一郎 (50372446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. FUJIMURA. Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ARITA Toshitsugu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMASHITA Yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SUZUKI Yoshiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 鄭剛

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 王同

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 徐恒昌

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. XU Heng Chang

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. WANG Ton

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ZHENG Gang

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WATANABE Akihiko 渡辺 昭彦

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Developing and clinical application of a highly reliable dentin-bonding system.Principal Investigator

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Excellent biocompatibility of MPC polymers as biomaterials evaluated by fibroblast and HL-60 cells.Principal Investigator

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WATANABE Akihiko 渡辺昭彦