OHTANI Haruo 大谷明夫

Researcher Number	30133987
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Affiliation (based on the past Project Information) *help	2003: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2001: 東北大学, 大学院・医学系研究所, 助教授 2000 – 2001: 東北大学, 医学部・医学系研究科, 助教授 1999 – 2001: 東北大学, 大学院・医学系研究科, 助教授 1999: Tohoku University School of Medicine Associate Professor, 大学院・医学研究科, 助教授 … More 1996 – 1999: Tohoku University School of Medicine, Associate Professor, 医学部, 助教授 1997: TOHOKU UNIVERSITY,School of Medicine Associate Professor, 歯学部, 助教授 1995: 東北大学, 医学部, 助手 1992 – 1993: 東北大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Human pathology / Digestive surgery Except Principal Investigator Digestive surgery / General surgery / Surgical dentistry / Human pathology / Orthopaedic surgery
Keywords	Principal Investigator 大腸癌 / MMP-1 / in situ hybridization / 炎症性腸疾患 / Colon Cancer / Immune response / Host Reaction / cancer metastasis / マクロファージ / 血行性転移 … More / 多変量解析 / 腫瘍免疫 / CD8陽性リンパ球 / 大腸がん / 免疫反応 / 宿主反応 / 癌転移 / MT1-MMP / matrix degradation / Inflammatory bowel disease / in situ ハイブリダイゼーション / 免疫組織化学 / 組織再構築 / マトリックスメタロプロティナーゼ / MTI-MMP / マトリックス分解酵素 / GATA gene / Colon cancer / Inflammatory Bowel Disease / 炎症 / 癌 / GATA-3 / GATA-2 / in situハイブリダイゼーション / GATA遺伝子 / Cancer patient / Immunosuppression / Lipocortin-1 / サプレッサーマクロファージ / 担癌患者 / 免疫抑制因子 / リポコルチン-1 / 転移 / uPAR / MMP-9 … More Except Principal Investigator 炎症性腸疾患 / マクロファージ / 潰瘍性大腸炎 / CD44 / angiogenesis / metastasis / 血管新生 / GFP / 転移 / 大腸癌 / VIP / 上皮細胞 / 樹状細胞 / VEGFR-3 / colorectal cancer / 生体顕微鏡 / B7-2 / Matrix metalloproteinase / FR118487 / inflammatory bowel disease / クローン病 / macrophage / ulcerative colitis / CRF / Foreign body reaction / チタニウム / 異物反応 / ウロコルチン / 神経ペプチド / 消化管粘膜 / 粘膜免疫機構 / 粘膜免疫 / 分子生物学 / Dendritic cell / Chemokine / Transplanted skin / Oral / ケモカイン / 移植皮膚 / 口腔 / flowcytometry / lymphocyte / dendritic cell / tumorimmunology / colorectal carcinoma / フローサイトメトリー / リンパ球 / 樹上細胞 / 腫瘍免疫 / lymph node / tumor growth / gastrointestinal cancer / 消火器癌 / リンパ節 / 腫瘍増殖 / 消化器癌 / Crohn's disease / microarray / CRP-ductin / epithelial cells / intestinal flora / クローン癌 / 無菌 / 腸内細菌 / マイクロアレイ / lymphangiogenesis / SCID / NOD / 血管内皮前駆細胞 / VEGF-D / VEGF-C / リンパ管新生 / intravital microscopy / 微小循環 / Langerhans cell / Tissue inhibitor of matrix metalloroteinase / Titanium / Skin Flap / ランゲルハンス細胞 / Tissue inhibitor of metalloproteinase / skin flap / lung metastasis / rat / osteosarcoma / angiogenesis inhibitor / マトリックスメタルプロテアーゼ / 担癌マウス / リンパ節転移(lymph node metastacis) / 多中心性骨肉腫(multifocal osteosarcoma) / 血行性転移(Rematogenous metastasis) / 肺転移(lung metostasis) / 骨肉腫(osteosarcoma) / 肺転移 / ラット / 骨肉腫 / 血管新生阻害剤 / germ-free / Ulcerative colitis / epithelial cell / クーロン病 / irritable bowel syndrome / urocortin / 11 β hydroxysteroid dehydrogenase / neuroendocrine system / mucosal immune system / 粘膜炎 / CRFファミリー / アポトーシス / 腸管粘膜上皮細胞 / 11-HDS / 胎児 / 大腸粘膜 / 潰瘍大腸炎 / 過敏性腸症候群 / 11β-hydroxy steroid dehydrogenase / 神経・内分泌系 / TGF-beta / Mandible / Titunium / 線維芽細胞 / 細胞増殖因子 / TGF-β / 下顎 / Steroid hormone / Hypothalamus / Macrophage / Chronic gastritis / Inflammatory bowel disease / Neuropeptide / Gastro-intestinal mucosa / Mucosal immune system / IL-6 / 先天性胆道閉鎖症 / アトピー性皮膚炎 / VIP受容体 / 消化管悪性腫瘍 / 内分泌系 / 中枢神経系 / ステロイドホルモン / 視床下部 / 慢性胃炎 / Neonate / Cell adhesion molecule / Immunohistochemistry / VIP receptor / Vasoactive intestinal peptide / Gut hormone / Mucosal immunity / Inflammatory bowed disease / エンドセリン / サブスタンスP / ニューロペプチド / in situ hypridization / 新生児 / 細胞接着分子 / 免疫組織化学 / VIPレセプター / vasoactive intestinal peptide(VIP) / 脳腸ペプチド / 抗微生物蛋白 Less

Inhibition of tumor growth, invasion, and metastasis by targeting CD44 molecule
- Principal Investigator
  
  MIZOI Takayuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  TOHOKU UNIVERSITY
A novel approach to analyze the immunological responses in human colorectal carcinoma
- Principal Investigator
  
  MIZOI Takayuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHOKU UNIVERSITY
Defense system in the intraorally transplanted skin : the relation between dendritic cells and chemokine system
- Principal Investigator
  
  FUMINORI Katou
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
  Tohoku University
Establishment and Analysis of the in vivo Human Tumor Angiogenesis Model
- Principal Investigator
  
  ISHII Seiichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Tohoku University
Analysis of gene expression associated with inflammatory bowel disease using cDNA microarray
- Principal Investigator
  
  SASAKI Iwao
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
蛋白発現ライブラリーを用いた腸内細菌に対する抗微生物蛋白同定の試み
- Principal Investigator
  
  FUKUSHIMA Kohei
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
Analysis of micromechanisms of metastasis using NOD/SCID-hu and GFP-transfectant human colorectal carcinoma cells
- Principal Investigator
  
  ISHII Seiichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Tohoku University
Clinicopathological analyses on the blood-borne metastasis in colorectal carcinomaPrincipal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Studies on the regulatory mechanism of immuno-inflammatory responses by the euroendocrine system in the gastrointestinal mucosa, and the mucosal injury by the failure of this regulatory function.
- Principal Investigator
  
  NAGURA Hiroshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Identification of Colon-specifi abnormal gene expression in alcerative colitis.
- Principal Investigator
  
  FUKUSHIMA Kouhei
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
The antitumor effect of angiogenesis inhibitor (FR118487) for transplantable rat osteosarcoma with lung metastatic potential
- Principal Investigator
  
  HATORI Masahito
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tohoku University
Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in the encapsulation process against titanium implant
- Principal Investigator
  
  KATOU Fuminori
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University
In situ expression of matrix-degrading enzymes in inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Expression of TGF-beta in foreign body reaction and fibrosis agaist titanium implant.
- Principal Investigator
  
  KATOU Fuminori
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  TOHOKU UNIVERSITY
癌浸潤に対する炎症性細胞反応とマトリックス分解酵素群の発現の意味の解明Principal Investigator
- Principal Investigator
  
  大谷明夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Closs talk between neuroendocrine and mucosal immune systems in the gastrointestinal mucosa and its disorder
- Principal Investigator
  
  NAGURA Hiroshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Possible involvement of vascular cells-related transcription factors in human inflammatory diseases and cancer tissue.Principal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Studies on the neuro-endocrine regulatory mechanism for mucosal immune system
- Principal Investigator
  
  NAGURA Hiroshi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  TOHOKU UNIVERSITY
Analysis of immunosupprative meclauism of Lipocortiut in tuwcr-beurig hestsits expression and action in wanPrincipal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHOKU UNIVERSITY

All 2003 2001

All Journal Article

[Journal Article] Differential expression of CCL 19 by DC-Lamp+ mature dendritic cells in human lymph node versus chronically inflamed skin.2003
- Author(s)
  Katou F, Ohtani H, Nakayama T, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  Journal of Pathology 199
  
  Pages: 98-106
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672078
[Journal Article] Differential expression of CCL19 by DC-Lamp+ mature dendritic cells in human lymph node versus chronically inflamad skin.2003
- Author(s)
  Katou F, Ohtani H, Nakayama T, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  J oumal of Pathology 199
  
  Pages: 98-106
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672078
[Journal Article] Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue.2001
- Author(s)
  Katou F, Ohtani H, Nakayama T, Ono K, Matsushima K, Saaristo A, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  American Journal of Pathology 158
  
  Pages: 1263-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672078
[Journal Article] Macrophage-derived chemokine (MDG/CCL22) and CCR4 are involved in the formation of Tlymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue.2001
- Author(s)
  Katou F, Ohtani H, Nakayama T, Ono K, Matsushima K, Saaristo A, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  American J oumal of Pathology 158
  
  Pages: 1263-1270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672078

1. SASAKI Iwao (60125557)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. SHIIBA Ken-ichi (90196345)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. FUKUSHIMA Kohei (20271900)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. SASANO Hironobu (50187142)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. NAGURA Hiroshi (90022821)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. ISHII Seiichi (60221066)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. MIZOI Takayuki (90271949)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. KATOU Fuminori (60204492)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
9. FUNAYAMA Yuji (50192315)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. NAITO Hiroo (90180223)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. KIMURA Noriko (80142975)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. SATO Yasufumi (50178779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. MASUDA Takayuki (00113910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAITOH Yoshihiro (10215569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. CHIBA Toshio (20171944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SUZUKI Takashi (10261629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HONGO Michio (60133948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HATORI Masahito (70208552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ISHII Keiko (00291253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SENBA Shuho (00302092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KAMEOKA Junichi (30261621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SAITO Kazuya (30343049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KATAYOSE Yu (20302151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 樋渡信夫 (00133950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 蝦名宣男 (40185137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SHIBATA Toshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 斎藤一也

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHTANI Haruo 大谷 明夫

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Clinicopathological analyses on the blood-borne metastasis in colorectal carcinomaPrincipal Investigator

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In situ expression of matrix-degrading enzymes in inflammatory bowel diseasePrincipal Investigator

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癌浸潤に対する炎症性細胞反応とマトリックス分解酵素群の発現の意味の解明Principal Investigator

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OHTANI Haruo 大谷明夫