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KADO Junko  角 純子 (岡部 純子)

ORCIDConnect your ORCID iD *help
… Alternative Names

角 純子 (岡部 純子)  カド ジユンコ

岡部 純子  オカベ ジュンコ

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Researcher Number 30161136
Other IDs
External Links
Affiliation (Current) 2025: 地方独立行政法人埼玉県立病院機構埼玉県立がんセンター(臨床腫瘍研究所), 臨床腫瘍研究所, 研究員
Affiliation (based on the past Project Information) *help 2006 – 2008: 埼玉県立がんセンター, 臨床腫瘍研究所, 主任研究員
2005: SAITAMA CANCER CENTER, RESEARCH INSTITUTE FOR CLINICAL ONCOLOGY, CHIEF RESEARCHER, 臨床腫瘍研究所, 専門研究員
2004: 埼玉県立がんセンター, 研究室, 主任研究員
2003: 埼玉県立がんセンター, 研究所・研究室, 主任研究員
2001 – 2002: 埼玉県立がんセンター, 研究室・専門研究員 … More
2000: 埼玉県立がんセンター, 研究所, 専門研究員
1998 – 2000: 埼玉県立がんセンター, 研究所, 主任研究員
1997: Saitama Cancer Center Chemotherapy, Research Institute, Chief Researcher, 研究所化学療法部, 主任研究員
1996 – 1997: 埼玉県立がんセンター, 研究所・化学療法部, 主任研究員 Less
Review Section/Research Field
Principal Investigator
Hematology / Hematology / Cell biology
Except Principal Investigator
Environmental pharmacy / Biological Sciences
Keywords
Principal Investigator
白血病細胞 / NM23 / 予後因子 / 白血病予後因子 / 分化誘導抑制因子 / nm23遺伝子 / 蛋白質 / 生理活性 / Prognostic factor / Serum diagnosis … More / Cytokine / Nm23 / Ezpression regulation / Phisiological activity / Protein / Cancer / 生存 / 増殖 / 単球 / NM23蛋白質 / 血清診断 / サイトカイン / 発現制御 / 癌 / SERUM / ELISA / LYMPHOMA / AML / PROGNOSTIC FACTOR / 文化誘導抑制因子 / ELISA法 / フローサイトメトリー / 悪性リンパ腫 / prognostic factor / differentiation / growth / differentiation inhibitory factor / leukemia cells / nm23 genes / 白血病治療抵抗性 / 増殖分化 / NM23結合蛋白質 / シグナル伝選 / シグナル伝達 / 蛋白 / がん … More
Except Principal Investigator
AhR / TCDD / Cell density / Schuttle protein / Nuclear export / Nuclear import / Phosphorylation / Endocrine Disrupters / DNAチップ / CYP1A1 / ARNT / p38MAPK / 細胞密度 / シャトル蛋白質 / 核外輸送 / 核移行 / リン酸化 / 内分泌撹乱物質 / 抗癌剤 / cytidine deaminase / cytosine arabinoside / 急性前骨髄球性白血病 / 急性骨髄性白血病 / サイトカイニン / 植物ホルモン / インターフェロン / 肺癌 / 白血病 / 細胞分化 / 分化誘導剤 / cotylenin A / interferon-α / 卵巣癌 / 分化誘導療法 / 分子標的治療 / がん治療 Less
  • Research Projects

    (6 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (6 People)
  •  Extracellular NM23 protein promotes the growth/survival of primary cultured human acute myelogenous leukemia cellsPrincipal Investigator

    • Principal Investigator
      KADO Junko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  NOVEL CYTOKINE-LIKE ACTIVITY OF SERUM NM23 PROTEINSPrincipal Investigator

    • Principal Investigator
      KADO Junko
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      SAITAMA CANCER CENTER
  •  分化誘導剤の作用機構の解析と治療効果の検討

    • Principal Investigator
      本間 良夫
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shimane University
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  Analysis of Molecular Mechanism of TCDD Toxicity

    • Principal Investigator
      KAWAJIRI Kaname
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Saitama Cancer Center
  •  The role of nm23 as a prognostic factor of leukemiaPrincipal Investigator

    • Principal Investigator
      OKABE-KADO Junko
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Saitama Cancer Center
  •  Nm23 gene expression and cellular growth and differentiationPrincipal Investigator

    • Principal Investigator
      OKABE Junko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Saitama Cancer Center

All 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] Focus on Neuroblastoma Research2007

    • Author(s)
      Junko Okabe, Kado, et al.
    • Publisher
      NOVA Publishers (印刷中)
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Book] Focus on Neuroblastoma Research2007

    • Author(s)
      Junko Okabe-Kado
    • Publisher
      NOVA Biomedical Books,New York
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Book] Focus on Neuroblastoma research Editor:Julio A. Fernandes2007

    • Author(s)
      Okabe-Kado, J., Kasukabe, T., and Kaneko, Y.
    • Publisher
      Clinical significance of serum NM23-H1 protein in neuroblastoma
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Journal Article] Cotylenin A, a new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G22008

    • Author(s)
      Kasukabe, T., Okabe-kado, J., Honma, Y.
    • Journal Title

      Cancer Sci 99

      Pages: 1693-1698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Journal Article] Cotylenin A, a new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G22008

    • Author(s)
      Kasukabe, T., Okabe-Kado, J., Honma, Y.
    • Journal Title

      Cancer Sci 99

      Pages: 1693-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Journal Article] Cotylenin A,a new differentiation inducer,and rapamycin cooperarively inhibit growth of cancer cells through induction of cyclin G2.2008

    • Author(s)
      Kasukabe, T., Okabe-Kado, J., and Honma, Y.
    • Journal Title

      Cancer Science 99(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Journal Article] Clinical significance of serum NM23-H1 protein in neuroblastoma2005

    • Author(s)
      Okabe-Kado, J., Kasukabe, T., et al.
    • Journal Title

      Cancer Science 96・10

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Clinical significance of serum NM23-H1 protein in neuroblastoma2005

    • Author(s)
      Okabe-Kado J., Kasukabe, T., et al.
    • Journal Title

      Cancer Science 96

      Pages: 653-660

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts.2005

    • Author(s)
      Kasukabe-T., Okabe-Kado, J., et al.
    • Journal Title

      Breast Cancer Res 7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts.2005

    • Author(s)
      Kasukabe-T., Okabe-Kado, J., et al.
    • Journal Title

      Breast Cancer Res. 7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] MmTRA1b/phospholipid scramblaes 1 gene expression is new prognostic factor for acute myelogenous leukemia.2004

    • Author(s)
      Yokoyama, A., Okabe-Kado, J., et al.
    • Journal Title

      Leukemia Res 28

      Pages: 149-157

    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] MmTRA1b/phospholipid scramblase 1 gene expression is new prognostic factor for acute myelogenous leukemia.2004

    • Author(s)
      Yokoyama, A., Okabe-Kado, J., et al.
    • Journal Title

      Leukemia Res. 28

      Pages: 149-157

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] MmTRA1b/phospholipid scramblase 1 gene expression is new prognostic factor for acute myelogenous leukemia.2004

    • Author(s)
      Yokoyama, A., Okabe-Kado, J., et al.
    • Journal Title

      Leukemia Res 28

      Pages: 149-157

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Clinical Significance of nm23-H1 Proteins Expressed in Cytoplasm in Diffuse Large B-cell Lymphoma.2004

    • Author(s)
      Niitsu, N., Okabe-Kado, J., et al.
    • Journal Title

      Clin Cancer Res 10

      Pages: 2482-2490

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Clinical Significance of nm23-H1 Proteins Expressed in Cytoplasmin Diffuse Large B-cell Lymphoma.2004

    • Author(s)
      Niitsu, N., Okabe-Kado, J., et al.
    • Journal Title

      Clin Cancer Res. 10

      Pages: 2482-2490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Physiological and pathological relevance of extracellular NM23/NDP kinases.2003

    • Author(s)
      Okabe-Kado, J., Kasukabe, T.
    • Journal Title

      J Bioenerg Biomemb 35

      Pages: 89-93

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Induction of apoptosis by combined treatment with differentiation-inducing agents and interferon-a in human lung cancer cells.2003

    • Author(s)
      Yamamoto-Yamaguchi, Y., Okabe Kado, J., et al.
    • Journal Title

      Anticancer Res 23

      Pages: 2537-2548

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Clinical significance of nm23-H1 proteins expressed on cell surface in Non-Hodgkin's lymphoma.2003

    • Author(s)
      Niitsu, N., Okabe-Kado, J., et al.
    • Journal Title

      Leukemia 17

      Pages: 196-202

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Induction of apoptosis by combined treatment with differentiation-inducing agents and interferon-a in human lung cancer cells.2003

    • Author(s)
      Yamamoto-Yamaguchi, Y., Okabe-Kado, J., et al.
    • Journal Title

      Anticancer Res. 23

      Pages: 2537-2548

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Serum levels of the nm23-H1 protein and their clinical implication in extranodal NK cell lymphoma.2003

    • Author(s)
      Niitsu, N., Okabe-Kado, J., et al.
    • Journal Title

      Leukemia 17

      Pages: 987-989

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Expression of nm23-H1 is associated with a poor prognosis in peripheral T-cell lymphoma.2003

    • Author(s)
      Niitsu, N., Nakamine, H., Okamoto, M., Okabe-Kado.J., et al.
    • Journal Title

      Br J Haematol 123

      Pages: 621-630

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Journal Article] Expression of nm23-H1 is associated with a poor prognosis in peripheral T-cell lymphoma.2003

    • Author(s)
      Niitsu, N., Nakamine, H., Okabe-Kado, J., et al.
    • Journal Title

      Br J Haematol. 123

      Pages: 621-630

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591033
  • [Presentation] EDG2/lpa1 Expression of Human Leukemia Cells during Myeloid Differentiation Induced by All-trans Retinoic Acid2008

    • Author(s)
      Okabe-Kado,J.,Kasukabe,T.,Honma,Y.,Kaneko,Y.Inverse Correlation of NM23 Expression with Lysophosphatidic Acid Receptor
    • Organizer
      50th Annual Meeting of American Society of Hematology
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2008-12-06
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] Expression with lysophosphatidic acid receptor EDG2/lpa1 expression of human leukemia cells during myeloid differentiation induced by all-trans retinoic acid2008

    • Author(s)
      Okabe-Kado, J., Kasukabe, T., Honma, Y., Kaneko, Y
    • Organizer
      50th Annual Meeting of American Society of Hematology
    • Place of Presentation
      San Francisco, CA, USA誌上発表
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] 白血病細胞におけるNM23結合蛋白質の探索と発現解析2008

    • Author(s)
      角 純子、粕壁 隆、金子安比古
    • Organizer
      第70回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] EDG2/LPA1 expression in leukemia cells and its association with NM23 expression2008

    • Author(s)
      角純子, 粕壁隆, 本間良夫, 金子安比古
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] EDG2/LPA1 expression in leukemia cells and its association with NM23 expression2008

    • Author(s)
      角 純子、粕壁 隆、本間良夫、金子安比古
    • Organizer
      第67回日本癌学会学
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] 白血病細胞におけるNM23蛋白質の機能と相互作用蛋白質の探索.2007

    • Author(s)
      角 純子
    • Organizer
      第69回日本血液学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] Glinical and biological significance of overexpression of NM23 in leukemia.2007

    • Author(s)
      Junko Okabe-Kado
    • Organizer
      7^<th> International Congress of the NDP Kinase/NM23/awd Family
    • Place of Presentation
      Dundee,Scotland,UK
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] Detection of NM23-interacting Proteins and their possible role on poor treatment outcome in leukemia.2007

    • Author(s)
      角 純子
    • Organizer
      第66回日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] Clinical and biological significace of overexpression of NM23 inleukemia2007

    • Author(s)
      Okabe-Kado,J., Kasukabe, T., and Kaneko.Y
    • Organizer
      7^<th> International Congress of the NDP Kinase/NM23/awd Family
    • Place of Presentation
      Dundee, UK
    • Year and Date
      2007-09-04
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] Detection of NM23-interactig proteins and their possible role on poor treatment out come in Leukemia2007

    • Author(s)
      角 純子、粕壁 隆、本間良夫、金子安比古
    • Organizer
      第66回日本癌学会学
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] 白血病細胞におけるNM23蛋白質の機能と相互作用蛋白質の探索2007

    • Author(s)
      角 純子、粕壁 隆、本間良夫、金子安比古
    • Organizer
      第69回日本癌学会学
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] Effect of Extracellular NM23 Protein on in Vitro Survival of Normal PBMNC and Acute Myeloid Leukemia Cells2006

    • Author(s)
      Okabe-Kado,J., Kasukabe, T., Kobayashi,H., Maseki, N., Honma, Y.,Kaneko.Y
    • Organizer
      48^<th> Annual Meetin of American Society of Hematology
    • Place of Presentation
      Orland, USA
    • Year and Date
      2006-12-10
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] 造血器腫瘍における血清NM23 蛋白質の生物学的意義2006

    • Author(s)
      角 純子
    • Organizer
      第1回山陰血液疾患研究会
    • Place of Presentation
      米子
    • Year and Date
      2006-02-17
    • Data Source
      KAKENHI-PROJECT-18591091
  • [Presentation] 細胞外NM23 蛋白血が初代培養の白血病細胞に誘導するシグナル伝達系2006

    • Author(s)
      角 純子、粕壁 隆、本間良夫、小林泰文、柵木信男、金子安比古
    • Organizer
      第65回日本癌学会学
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-28
    • Data Source
      KAKENHI-PROJECT-18591091
  • 1.  本間 良夫 (70142114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  粕壁 隆 (50152658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  山口 ゆり (80166628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KAWAJIRI Kaname (50142112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Junko (60167137)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  IKUTA Togo (00262072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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