MISHIMA Yukio 三嶋行雄

… Alternative Names

三島行雄ミシマユキオ

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Researcher Number	30166003
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2009: 新潟大学, 医歯学系, 准教授 2005 – 2006: 新潟大学, 医歯学系, 助教授 2003 – 2004: 新潟大学, 大学院・医歯学総合研究科, 助教授 2001: NIIGATA UNIVERSITY, Graduate School of Medical and Dental Sciences, Associate, Professor, 大学院・医歯学総合研究科, 助教授 1997 – 2000: 新潟大学, 医学部, 助教授 … More 1986 – 1990: 新潟大学, 医学部, 講師 1987: Niigata University Lecturer, 講師 1986: 新大, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator General medical chemistry Except Principal Investigator General medical chemistry / Risk sciences of radiation/Chemicals / Biological Sciences
Keywords	Principal Investigator rRNA / 転写調節 / プロセッシング / 転写因子 / Deletion mutants / rRNA processing / Formation of ribosome / Ribosome / SIマッピング法 / U3RNA … More / 共通塩基配列 / パルス・チェイス法 / プロセシング / 無細胞系 / リボソーム形成 / ΓRNA / DNase I footprinting / microsatellite / homopurinesequences / DNA-DNA complex / reconstituted chromatin / chromosome / GGA repeats / repetitive sequences / DNAペアリング / トリプレックス / 再構成ヌクレオソーム / 原子間力顕微鏡 / トリフレックス / DNaseIプットフリント法 / DNaseIフットプリント法 / マイクロサテライト / ホモプリン配列 / DNA-DNA複合体 / 再構成クロマチン / 染色体 / GGAリピート / 反復配列 / プロセッシングシグナル / ADP-リボシル化 / NAD / 転写 / 無細胞プロセッシッグ系 / 無細胞転写系 / NAD^+ / RNAポリメラ-ゼI / ADPーリボシル化 / マウスrRNA遺伝子 … More Except Principal Investigator リンパ腫 / Bcl11b / アポトーシス / Bcl11b遺伝子 / 5SRNP / TMV-RNA / ROS / 発がん感受性 / Chk1 / Bclllb遺伝子 / 細胞増殖 / がん抑制遺伝子 / 反復配列 / DNA binding protein / Recombination / Minisatellite / ホットスポット / 染色体 / 遺伝的組み換え / 結合タンパク / ゲル・シフト法 / ミニサテライト / Rabbit reticulocyte lysate / Initiator AUG codon / Initiation of protein synthesis / 架橋 / Ω断片 / 紫外線照射 / リボソーム蛋白 / 開始複合体 / 開始AUG配列 / 80S開始複合体 / Pサイト / ウサギライセート / 開始AUGコドン / タンパク合成開始 / Atrophic thymus / susceptibility / radiation / lymphomas / 2 / MTF-1 / アポーシス / 発がん感受性遺伝子 / リンパ腫抑制遺伝子 / 萎縮胸腺 / 放射線 / blueprints / allele-specific / chromatin packaging / genomic imprinting / アレル / 多型 / クロマチン分画法 / コンジェニックマウス / 臓器特異的発見 / クロマチン凝縮度 / 欠失領域 / 内部欠失 / ゲノムインプリント / Blueprint / アレル特異的な発現 / クロマチン凝縮 / ゲノムインプリンティング / MYOSIN GENE / GENOME ANALYSIS / POSITIONAL CLONING / GENETIC DEAFNESS / ミオシン遺伝子 / ゲノム解析 / ポジショナルクローニング / 遺伝子難聴 / シグナル伝達 / 遺伝学 / 電離放射線 / がん / β-カテニン / 腸管腫瘍 / 癌細胞幹細胞 / 放射線発がん初期過程 / 放射線ターゲット細胞 / 前リンパ腫細胞・腸管腫瘍 / 電離放射線影響 / 胸腺リンパ腫 / 亜鉛フィンガードメイン / TOP/FOPflash / 大腸がん / Wnt/β-cateninシグナル / 機能解析 / 研究分担者 / DNA構造特性 / 再構成クロマチン / ユウクロマチン / ヘテロクロマチン / 核マトリックス / 染色体ドメイン / DNA-DNAペアリング / GGA反復配列 Less

Host factors and genetic mutations in radiation carcinogenesis
- Principal Investigator
  
  KOMINAMI Ryo
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Niigata University
Isolation and characterization of cancer-related genes in mouse models
- Principal Investigator
  
  KOMINAMI Ryo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Isolation and characterization of genes involved in radiogenic mouse thymic lymphomas
- Principal Investigator
  
  KOMINAMI Ryo
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Niigata University
染色体ドメインの形成機構と動態:反復配列を視点として
- Principal Investigator
  
  KOMINAMI Ryo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Niigata University
Differential chromatin packaging of genomic imprinted regions between expressed and non-expressed alleles
- Principal Investigator
  
  KOMINAMI Ryo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  NIIGATA UNIVERSITY
Analysis of molecular structure of nucleosomes consisting of repetitive DNA sequences and their function in chromatinPrincipal Investigator
- Principal Investigator
  
  MISHIMA Yukio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  NIIGATA UNIVERSITY
A novel type of myosin encoded by the mouse deafness gene shaker-2
- Principal Investigator
  
  KOMINAMI Ryo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  NIIGATA UNIVERSITY
動物細胞rRNA遺伝子の転写調節因子の解析Principal Investigator
- Principal Investigator
  
  三島行雄
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Niigata University
動物細胞rRNAの転写とプロセッシングの共役Principal Investigator
- Principal Investigator
  
  三嶋行雄
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Niigata University
Proteins Binding to Cytosine-Rich Strand of Hypervariable Minisatellite DNA
- Principal Investigator
  
  KOMINAMI Ryo
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Niigata University
動物細胞rRNA合成のプロセッシングを含む制御機構の研究Principal Investigator
- Principal Investigator
  
  三嶋行雄
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Niigata University
Identification of initiator AUG binding proteins in initiation step of protein synthesis
- Principal Investigator
  
  TAKAHASHI Yoshiaki
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Niigata University
Studies on processing of rRNA and formation of ribosome in animal cellsPrincipal Investigator
- Principal Investigator
  
  MISHIMA Yukio
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Niigata University

All 2010 2009 2008 2007 2006 2005

All Journal Article Book

[Book] γ-Ray-Induced Mouse Thymic Lymphomas : Bclllb Inactivation and Prelymphoma Cells. Springer Library of Congress Control Number : 2008937558(Eds, Nakashima et al)(Radiation Health Risk Sciences)2009
- Author(s)
  R Kominami, H Ohi, K Kamimura, M Maruyama, T Yamamoto, K Takaku, S Morita, R Go, Y Mishima.
- Data Source
  KAKENHI-PROJECT-17013033
[Book] Radiation Health Risk Sciences(Nakashima, et.al(Eds))(γ-Ray-Induced mouse Thymic Lymphomas : Bc111b Inactivation and Prelymphoma cells)2009
- Author(s)
  R kominami, H Ohi, K Kamimura, M Maruyama, T Yamamoto, K Takaku, S Morita, R Go, Y Mishima
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18201009
[Book] Radiation Health Risk Sciences (Eds, Nakashima, et al,)(Springer Library of Congress Control Number:2008937558, γ-Ray-Induced mouse Thymic Lymphomas:Bcl11b Inactivation and Prelymphoma cells)2009
- Author(s)
  R Kominami, H Ohi, K Kamimura, M Maruyama, T Yamamoto, K Takaku, S Morita, R Go, Y Mishima
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Clonally expanding thymocytes having lineage capability inγ-ray induced mouse atrophic thymus.2010
- Author(s)
  Yamamoto T, Morita S, Go E, Obata M, Katsuragi Y, Fujita Y, Maeda Y, Yokoyama M, Aoyagi Y, Ichikawa H, Mishima Y, Kominami R
- Journal Title
  
  Int. J. Radiation Oncology Biol. 77
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Bcl11b heterozygosity promotes clonal expansion and differentiation arrest of thymocytes inγ-irradiated mice.2010
- Author(s)
  Go R, Hirose S, Morita S, Yamamoto T, Katsuragi Y, Mishima Y, Kominami R
- Journal Title
  
  Cancer Science (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Clonally expanding thymocytes having lineage capability in y-ray induced mouse atrophic thymus.2010
- Author(s)
  Yamamoto T, Morita S, Go E, Obata M, Katsuragi Y, Fujita Y, Maeda Y, Yokoyama M, Aoyagi Y, Ichikawa H, Mishima Y, Kominami R.
- Journal Title
  
  Int.J.Radiation Oncology Biol. 77
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Clonally expanding thymocytes having lineage capability in γ-ray induced mouse atrophic thymus.2010
- Author(s)
  Yamamoto T, Morita S, Go E, Obata M, Katsuragi Y, Fujita Y, Maeda Y, Yokoyama M, Aoyagi Y, Ichikawa H, Mishima Y, Kominami R.
- Journal Title
  
  Int.J.Radiation Oncology Biol Phys 77(1)
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Bclllb heterozygosity promotes clonal expansion and differentiation arrest of thymocytes in y-irradiated mice.2010
- Author(s)
  Go R, Hirose S, Morita S, Yamamoto T, Katsuragi Y, Mishima Y, Kominami R.
- Journal Title
  
  Cancer Science 101
  
  Pages: 347-1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Bclllb heterozygosity promotes clonal expansion and differentiation arrest of thymocytes in γ-irradiated mice.2010
- Author(s)
  Go R, Hirose S, Morita S, Yamamoto T, Katsuragi Y, Mishima Y, Kominami R.
- Journal Title
  
  Cancer Science (In Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Clonally expanding thymocytes having lineage capability in γ-ray induced mouse atrophic thymus.2010
- Author(s)
  Yamamoto T, Morita S, Go E, Obata M, Katsuragi T, Fujita Y, Maeda Y, Yokoyama M, Aoyagi Y, Ichikawa H, Mishima Y, Kominami R.
- Journal Title
  
  Int.J.Radiation Oncology Biol Phys
  
  Volume: 77 Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Effect of Bclllb genotypes and gamma-radiation on the development of mouse thymic lymphomas.2008
- Author(s)
  Yoshikai Y, Sato T, Morita S, Kohara Y, Takagi R, Mishima Y, Kominami R.
- Journal Title
  
  Biochem Biophys Res Commun. 373
  
  Pages: 282-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Effect of Bcl11b genotypes and gamma-radiation on the development of mouse thymic lymphomas.2008
- Author(s)
  Yoshikai Y, Sato T, Morita S, Kohara Y, Takagi R, Mishima Y, Kominami R
- Journal Title
  
  Biochem Biophys Res Commun. 373
  
  Pages: 282-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Mtf-1lymphoma-susceptibility locus affects retention of large thymocytes with high ROS levels in mice after γ-irradiation.2007
- Author(s)
  Maruyama M, Yamamoto T, Kohara Y, Katsuragi Y, Mishima Y, Aoyagi Y, Kominami R.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 354
  
  Pages: 209-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication stress andd amages.2007
- Author(s)
  Kamimura K, Mishima Y, Obata M, Endo T, Aoyagi Y, Kominami R
- Journal Title
  
  Oncogene 26
  
  Pages: 5840-5850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Multi-step lymphomagenesis deduced from DNA changes in thymic lymphomas and atrophic thymuses at various times after y-irradiation.2007
- Author(s)
  Ohi H, Mishima Y, Kamimura K, Maruyama M, Sasai K, Kominami R.
- Journal Title
  
  Oncogene 26
  
  Pages: 5280-5289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Mtf-1lymphoma-susceptibility locus affects retention of large thymocytes with high ROS levels in mice afterγ-irradiation.2007
- Author(s)
  Maruyama M, Yamamoto T, Kohara Y, Katsuragi Y, Mishima Y, Aoyagi Y, Kominami R
- Journal Title
  
  Biochem. Biophys. Res. Commun. 354
  
  Pages: 209-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Multi-step lymphomagenesis deduced from DNA changes in thymic lymphomas and atrophic thymuses at various times afterγ-irradiation.2007
- Author(s)
  Ohi H, Mishima Y, Kamimura K, Maruyama M, Sasai K, Kominami R
- Journal Title
  
  Oncogene 26
  
  Pages: 5280-5289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Multi-step lymphomagenesis deduced from DNA changes in thymic lymphomas and atrophic thymuses at various times after γ-irradiation2007
- Author(s)
  H. Ohi, Y. Mishima, K. Kamimura, M. Maruyama, K. Sasai and R. Kominami
- Journal Title
  
  Oncogene 26
  
  Pages: 5280-5289
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Haploinsufficiency of Bcl11b for suppression of lymphomagenesis and thymocyte development.2007
- Author(s)
  Kamimura K, Ohi H, Kubota T, Okazuka K, Yoshikai Y, Wakabayashi Y, Aoyagi Y, Mishima Y, Kominami R
- Journal Title
  
  Biochem. Biophys. Res. Commun 355
  
  Pages: 538-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Haploinsufficiency of Bclllb for suppression of lymphomagenesis and thymocyte development.2007
- Author(s)
  Kamimura K, Ohi H, Kubota T, Okazuka K, Yoshikai Y, Wakabayashi Y, Aoyagi Y, Mishima Y, Kominami R.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 355
  
  Pages: 538-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Lack of Bclllb tumor suppressor results in vulnerability to DNA replication stress andd amages.2007
- Author(s)
  Kamimura K, Mishima Y, Obata M, Endo T, Aoyagi Y, Kominami R.
- Journal Title
  
  Oncogene 26
  
  Pages: 5840-5850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Expression of TCRαβpartly rescues developmental arrest and apoptosis ofαβT cells in Bcl11b-/-mice.2006
- Author(s)
  Inoue J, Kanefuji T, Okazuka K, Watanabe H, Mishima Y, Kominami R
- Journal Title
  
  J. Immunology 176
  
  Pages: 5871-5879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Expression of TCRαβpartly rescues developmental arrest and apoptosis of αβT cells in Bclllb-/-mice.2006
- Author(s)
  Inoue J, Kanefuji T, Okazuka K, Watanabe H, Mishima Y, Kominami R.
- Journal Title
  
  J Immunology 176
  
  Pages: 5871-5879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013033
[Journal Article] Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1)2005
- Author(s)
  Y. Tamura, M. Maruyama, Y. Mishima, H. Fujisawa, M. Obala, Y Kodauia, Y. Yoshikai, Y. Aoyagi, O. Niwa, W. Schaffner and R. Kominami
- Journal Title
  
  Oncogene 24
  
  Pages: 399-406
- Data Source
  KAKENHI-PROJECT-18201009
[Journal Article] Comparison of properties of spontaneous and radiation-induced mouse thymic lymphomas : role of Trp53 and radiation2005
- Author(s)
  T. Kubota, Y. Yoshikai, Y Tamura, Y. Mishima, Y. Aoyagi, O. Niwa and R. Kominami
- Journal Title
  
  Radiation Research 163
  
  Pages: 159-164
- Data Source
  KAKENHI-PROJECT-18201009

1. KOMINAMI Ryo (40133615)

# of Collaborated Projects: 7 results

# of Collaborated Products: 25 results
2. KATSURAGI Yoshinari (60401759)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. OBATA Miki (00420307)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. TAKAHASHI Yoshiaki (60115045)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. HIROSE Satoshi (10415276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. INOUE Jun (70323962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. NITSUMA Takashi (70107796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUWANO Yuh (70178151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OGATA Kikuo (00018285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KENMOCHI Naoya (00133124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UCHIUMI Tshio (50143764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MISHIMA Yukio 三嶋 行雄

三島 行雄 ミシマ ユキオ

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Analysis of molecular structure of nucleosomes consisting of repetitive DNA sequences and their function in chromatinPrincipal Investigator

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動物細胞rRNA遺伝子の転写調節因子の解析Principal Investigator

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動物細胞rRNAの転写とプロセッシングの共役Principal Investigator

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動物細胞rRNA合成のプロセッシングを含む制御機構の研究Principal Investigator

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Studies on processing of rRNA and formation of ribosome in animal cellsPrincipal Investigator

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[Book] γ-Ray-Induced Mouse Thymic Lymphomas : Bclllb Inactivation and Prelymphoma Cells. Springer Library of Congress Control Number : 2008937558(Eds, Nakashima et al)(Radiation Health Risk Sciences)2009

Author(s)

Data Source

[Book] Radiation Health Risk Sciences(Nakashima, et.al(Eds))(γ-Ray-Induced mouse Thymic Lymphomas : Bc111b Inactivation and Prelymphoma cells)2009

Author(s)

Publisher

Data Source

[Book] Radiation Health Risk Sciences (Eds, Nakashima, et al,)(Springer Library of Congress Control Number:2008937558, γ-Ray-Induced mouse Thymic Lymphomas:Bcl11b Inactivation and Prelymphoma cells)2009

MISHIMA Yukio 三嶋行雄

三島行雄ミシマユキオ