YOKOTANI Kunihiko 横谷邦彦

… Alternative Names

YOKOTANI Kumihiko 横谷邦彦

Less

Researcher Number	30174858
Other IDs
Affiliation (based on the past Project Information) *help	2009 – 2010: Kochi University, 教育研究部・医療学系, 教授 2008: Kochi University, 教育研究部医療学系, 教授 1995 – 1997: 高知医科大学, 医学部, 助教授 1992 – 1993: 高知医科大学, 医学部, 助手 1986: Department of Pharmacology, Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 / General pharmacology / General internal medicine (including Psychosomatic medicine) Except Principal Investigator 応用薬理学・医療系薬学
Keywords	Principal Investigator 交感神経 / Noradrenaline / Alpha-1 adrenoceptors / Sympathetic nervous system / Gastric mucosal blood flow / Gastric acid secretion / 1-メチルヒスタミン / ヒスタミン / アドレナリン【α_1】受容体 / 胃粘膜血流量 … More / 胃酸分泌 / Acid secretion / Nitric oxide / Thromboxane A2 / Prostaglandin / Adrenaline / Adrenal medulla / Sympathetic nerve / オキシヘモグロビン / NO合成酵素阻害薬 / インドメタシン / 一酸化窒 / トロンボキサンA2 / プロスタグランジン / インターロイキン1β / 一酸化窒素 / アドレナリン / ノルアドレナリン / 副腎髄質 / Alpha-adrenoceptor / Muscarinic receptor / Stomach / Gastric sympathetic nerve / Acetylcholine / Vagal nerve / α2アドレナリン受容体 / M2ムスカリン受容体 / アセチルコリン / アルファ-.アドレナリン受容体 / ノルアドレナリン遊離 / アルファー・アドレナリン受容体 / ムスカリン受容体 / 胃 / 胃交感神経 / アセチルコリン遊離 / 迷走神経 / 副腎髄質系 / 交感神経系 / CB取り込み阻害藥 / CB1受容体遮断藥 / CB1受容体刺激藥 / 脳内機序 / 交感神経-副腎髄質系賦活 / 2-アラキドニルグリセロール(2-AG) / モノアシルグリセロールリパーゼ / 中枢性交感神経-副腎髄質系の賦活 / 脳内ニコチン受容体 / 喫煙 / エンドカンナビノイド / 2-アラキドノイルグリセロール / ジアシルグリセロールリパーゼ / ホスホリパーゼC / アラキドン酸カスケード / 交感神経-副腎髄質系の中枢性賦活 … More Except Principal Investigator Vascularly-perfused gastric preparation / Evaluation method of drug action / Gastric function / Acetylcholine / Noradrenaline / Glutamic acid / アミノ酸 / カルシウムチャネル / 神経伝達物質 / β-エンドルフィン / 血管灌流胃嚢標本 / 薬物作用検定方法 / 胃機能 / アセチルコリン / ノルアドレナリン / グルタミン酸 Less

Roles of endocannabinoid in the modulation of central sympatho-adrenomedullary outflow in ratPrincipal Investigator
- Principal Investigator
  
  YOKOTANI Kunihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kochi University
Roles of brain nitric oxide and prostaglandins in the regulation of central sympatho-adrenomedullary outflow in ratsPrincipal Investigator
- Principal Investigator
  
  YOKOTANI Kunihiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kochi Medical School
EVALUATION OF AN ISOLATED VASCULARLY-PERFUSED RAT STOMACH AS A USEFUL EXPERIMENTAL MODEL FOR STUDIES OF GASTROIINTESTINAL PHARMACOLOGY
- Principal Investigator
  
  OSUMI Yoshitsugu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kochi Medical School
Releasing mechanisms of acetylcholine from an isolated rat stomachPrincipal Investigator
- Principal Investigator
  
  YOKOTANI Kunihiko
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kochi Medical School
The role of sympathetic nervous system in regulation of gastric acid secretion.Principal Investigator
- Principal Investigator
  
  YOKOTANI Kunihiko
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kochi Medical School

All 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Endogenously generated 2-AG plays an inhibitory role in bombesin- induced activation of central adrenomedullary outflow in rats.2011
- Author(s)
  Shimizu T, Lu L, Yokotani K.
- Journal Title
  
  Eur.J.Pharmacol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Endogenously generated 2-AG plays an inhibitory role in bombesin-induced activation of central adrenomedullary outflow in rats2011
- Author(s)
  Shimizu T, Lu L, Yokotani K
- Journal Title
  
  Eur J Pharmacol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Brain a4β2 nicotinic acetylcholine receptors are involved in the secretion of noradrenaline and adrenaline from adrenal medulla in rats2011
- Author(s)
  Shimizu T, Tanaka K, Hasegawa T, Yokotani K
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 654 Pages: 241-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Brain a4β2 nicotinic acetylcholine receptors are involved in the secretion of noradrenaline and adrenaline from adrenal medulla in rats.2011
- Author(s)
  Shimizu T, Tanaka K, Hasegawa T, Yokotani K.
- Journal Title
  
  Eur. J. Pharmacol. 654
  
  Pages: 242-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Possible inhibitory roles of endogenous 2-arachidonoylglycerol during CRF-induved activatiuon of central sympatho- adrenomedullary outflow in anesthetized rats.2010
- Author(s)
  Shimizu T, Lu L, Yokotani K.
- Journal Title
  
  Eur. J. Pharmacol. 641
  
  Pages: 54-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Possible inhibitory roles of endogenous 2-arachidonoylglycerol during CRF-induved activatiuon of central sympatho-adrenomedullary outflow in anesthetized rats2010
- Author(s)
  Shimizu T, Lu L, Yokotani K
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 641 Pages: 54-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Brain cyclooxygenase and prostanoid TP receptors are involved in centrally administered epibatidine-induced secretion of noradrenaline and adrenaline from the adrenal medulla in rats.2009
- Author(s)
  Shimizu T, Yokotani K.
- Journal Title
  
  Eur. J. Pharmacol. 606
  
  Pages: 77-83
- NAID
  120001592112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Acute cold exposureinduced down-regulation of CIDEA, cell deathinducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors.2009
- Author(s)
  Shimizu T, Yokotani K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 387
  
  Pages: 294-299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Effects of centrally administered prostaglandin E3 and thromboxane A3 on plasma noradrenaline and adrenaline in rats : Comparison with prostaglandin E2 and thromboxane A22009
- Author(s)
  Shimizu T, Yokotani K.
- Journal Title
  
  Eur J Pharmacol 611
  
  Pages: 30-34
- NAID
  120001592111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Acute cold exposure-induced down-regulation of CIDEA, cell death-inducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors2009
- Author(s)
  Shimizu T, Yokotani K.
- Journal Title
  
  Biochem Biophys Res Commun. 387
  
  Pages: 294-299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Brain cyclooxygenase and prostanoid TP receptors are involved in centrally administered epibatidine-induced secretion of noradrenaline and adrenaline from the adrenal medulla in rats2009
- Author(s)
  Shimizu T, Yokotani K.
- Journal Title
  
  Eur J Pharmacol 606
  
  Pages: 77-83
- NAID
  120001592112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Effects of centrally administered prostaglandin E3 and thromboxane A3 on plasma noradrenaline and adrenaline in rats : Comparison with prostaglandin E2 and thromboxane A2.2009
- Author(s)
  Shimizu T, Yokotani K.
- Journal Title
  
  Eur. J. Pharmacol. 611
  
  Pages: 30-34
- NAID
  120001592111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Brain cyclooxygenase and prostanoid TP receptors are involved in centrally administered epibatidine-induced secretion of noradrenaline and adrenaline from the adrenal medulla in rats2009
- Author(s)
  Takahiro Shimizu, Kunihiko Yokotani
- Journal Title
  
  Eur. J. Pharmacol. 606
  
  Pages: 77-83
- NAID
  120001592112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Roles of the brain phospholipase C, 2-arachidonoylglycerol and arachidonic acid in the central activation of the sympatho-adrenomedullary outflow in rats (review).2008
- Author(s)
  Shimizu T, Yokotani K.
- Journal Title
  
  自律神経第45巻
  
  Pages: 167-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Brain neuronal/inducible nitric oxide synthases and cyclooxygenase-1are involved in the bombesin-induced activation of central adrenomedullary outflow in rats2008
- Author(s)
  Lu L, Shimizu T, Nakamura K, Yokotani K
- Journal Title
  
  Eur. J. Pharmacol. 590
  
  Pages: 177-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Centrally administered neuromedin U elevates plasma adrenaline by brain prostanoid TP receptor-mediated mechanisms in rats2008
- Author(s)
  Sasaki T, Shimizu T, Wakiguchi H, Yokotani K
- Journal Title
  
  Eur. J. Pharmacol. 592
  
  Pages: 81-86
- NAID
  120001614070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Centrally administered neuromedin U elevates plasma adrenaline by brain prostanoid TP receptor-mediated mechanisms in rats.2008
- Author(s)
  Sasaki T, Shimizu T, Wakiguchi H, Yokotani K.
- Journal Title
  
  Eur. J. Pharmacol. 592
  
  Pages: 81-86
- NAID
  120001614070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Journal Article] Brain neuronal/inducible nitric oxide synthases and cyclooxygenase-1 are involved in the bombesin- induced activation of central adrenomedullary outflow in rats.2008
- Author(s)
  Lu L, Shimizu T, Nakamura K, Yokotani K.
- Journal Title
  
  Eur. J. Pharmacol. 590
  
  Pages: 177-184
- NAID
  120001614071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] Endogenously generated 2-AG plays an inhibitory role in bombesin-induced activation of central adrenomedullary outflow in rats2010
- Author(s)
  Shimizu T, Lu L, Yokotani K
- Organizer
  5^<th> International Peptide Symposium
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2010-11-09
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in corticotropin-releasing factor-induced activation of central sympatho-adrenomedullary outflow in rats.2010
- Author(s)
  清水孝洋, 盧連依, 横谷邦彦
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  Kyoto (Japan).
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 内因性に生成された2-アラキドノイルグリセロールはコルチコトロピン放出因子による中枢性交感神経-副腎髄質系賦活に対し抑制性作用を示す2010
- Author(s)
  清水孝洋, 盧連依, 横谷邦彦
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 内因性に生成された2-アラキドノイルグリセロールはコルチコトロピン放出因子による中枢性交感神経-副腎髄質系賦活に対し抑制性作用を示す2010
- Author(s)
  清水孝洋, 盧連依, 横谷邦彦
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 急性寒冷暴露ラットの褐色脂肪組織において交感神経によるアドレナリンβ3受容体の活性化によりCIDEA (cell death-inducing DNA fragmentation factor-α-like effector A)の発現低下が惹起される2009
- Author(s)
  清水孝洋, 横谷邦彦
- Organizer
  第13回活性アミンに関するワークショップ
- Place of Presentation
  津
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 脳内の内因性NOによるCOXのS-ニトロシル化が中枢性に投与されたボンベシンによる中枢性副腎髄質系賦活に関与する可能性について2009
- Author(s)
  盧連依, 清水孝洋, 中村久美子, 横谷邦彦
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 脳内エンドカンナビノイドはコルチコトロピン放出因子による中枢性交感神経-副腎髄質系賦活を抑制性に制御する2009
- Author(s)
  清水孝洋, 横谷邦彦
- Organizer
  第62回日本自律神経学会総会
- Place of Presentation
  和歌山
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 脳内の内因性NOによるCOXのS-ニトロシル化が中枢性に投与されたボンペシンによる中枢性副腎髄質系賦活に関与する可能性について2009
- Author(s)
  盧連依, 清水孝洋, 中村久美子, 横谷邦彦
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 中枢性に投与されたエピバチジンによる副腎髄質からのノルアドレナリンとアドレナリン分泌には脳内シクロオキシゲナーゼおよびプロスタノイドTP受容体が関与する2009
- Author(s)
  清水孝洋, 横谷邦彦
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] バソプレシンにより惹起される中枢性副腎髄質系賦活において脳内2-アラキドノイルグリセロールは二方向性作用を示す2008
- Author(s)
  清水孝洋, 横谷邦彦
- Organizer
  第61回日本自律神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] バソプレシンによる中枢性副腎髄質系賦活における脳内2-アラキドノイルグリセロールの二面性作用について2008
- Author(s)
  清水孝洋, 盧連依, 佐々木剛, 中村久美子, 山口奈緒子, 岡田尚志郎, 横谷邦彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] 脳室内投与したNMDAによる副腎髄質形賦活機構の薬理学的解析2008
- Author(s)
  岡田尚志郎, 山口奈緒子, 清水孝洋, 横谷邦彦
- Organizer
  第61回日本自律神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-20590702
[Presentation] ボンベシンによる中枢性副腎髄質系賦活に関与する脳内NOSアイソフォムの解析2008
- Author(s)
  盧連依, 清水孝洋, 中村久美子, 岡田尚志郎, 山口奈緒子, 佐々木剛, 横谷邦彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20590702

1. SHIMIZU Takahiro (00363276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
2. TANAKA Kenjirou (30552260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. OSUMI Yoshitsugu (80025634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SANO Shuichi (50274379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OKUMA Yasunobu (20127939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山口奈緒子 (50380324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

YOKOTANI Kunihiko 横谷 邦彦

YOKOTANI Kumihiko 横谷 邦彦

Research Projects

Research Products

Co-Researchers

Roles of endocannabinoid in the modulation of central sympatho-adrenomedullary outflow in ratPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of brain nitric oxide and prostaglandins in the regulation of central sympatho-adrenomedullary outflow in ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EVALUATION OF AN ISOLATED VASCULARLY-PERFUSED RAT STOMACH AS A USEFUL EXPERIMENTAL MODEL FOR STUDIES OF GASTROIINTESTINAL PHARMACOLOGY

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Releasing mechanisms of acetylcholine from an isolated rat stomachPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of sympathetic nervous system in regulation of gastric acid secretion.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Endogenously generated 2-AG plays an inhibitory role in bombesin- induced activation of central adrenomedullary outflow in rats.2011

Author(s)

Journal Title

Data Source

[Journal Article] Endogenously generated 2-AG plays an inhibitory role in bombesin-induced activation of central adrenomedullary outflow in rats2011

Author(s)

Journal Title

Data Source

[Journal Article] Brain a4β2 nicotinic acetylcholine receptors are involved in the secretion of noradrenaline and adrenaline from adrenal medulla in rats2011

Author(s)

Journal Title

Data Source

[Journal Article] Brain a4β2 nicotinic acetylcholine receptors are involved in the secretion of noradrenaline and adrenaline from adrenal medulla in rats.2011

Author(s)

Journal Title

Data Source

[Journal Article] Possible inhibitory roles of endogenous 2-arachidonoylglycerol during CRF-induved activatiuon of central sympatho- adrenomedullary outflow in anesthetized rats.2010

Author(s)

Journal Title

Data Source

[Journal Article] Possible inhibitory roles of endogenous 2-arachidonoylglycerol during CRF-induved activatiuon of central sympatho-adrenomedullary outflow in anesthetized rats2010

Author(s)

Journal Title

Data Source

[Journal Article] Brain cyclooxygenase and prostanoid TP receptors are involved in centrally administered epibatidine-induced secretion of noradrenaline and adrenaline from the adrenal medulla in rats.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Acute cold exposureinduced down-regulation of CIDEA, cell deathinducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effects of centrally administered prostaglandin E3 and thromboxane A3 on plasma noradrenaline and adrenaline in rats : Comparison with prostaglandin E2 and thromboxane A22009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Acute cold exposure-induced down-regulation of CIDEA, cell death-inducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors2009

Author(s)

Journal Title

Data Source

[Journal Article] Brain cyclooxygenase and prostanoid TP receptors are involved in centrally administered epibatidine-induced secretion of noradrenaline and adrenaline from the adrenal medulla in rats2009

Author(s)

Journal Title

YOKOTANI Kunihiko 横谷邦彦

YOKOTANI Kumihiko 横谷邦彦