Kuroiwa Toshihiko 黒岩敏彦

… Alternative Names

KUROIWA Toshihiko 黒岩敏彦

黒岩俊彦クロイワトシヒコ

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Researcher Number	30178115
Other IDs
External Links
Affiliation (Current)	2025: 大阪医科薬科大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 大阪医科薬科大学, その他部局等, 名誉教授 2019 – 2020: 大阪医科大学, その他部局等, 名誉教授 2001 – 2018: 大阪医科大学, 医学部, 教授 1988: Division of Pathology, Malicious Disease
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Neurosurgery / Applied health science / Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery / Medical systems / Neurosurgery / Tumor diagnosis
Keywords	Principal Investigator 光線力学診断 / 光線力学療法 / 光線力学治療 / 脳腫瘍 / ５アミノレブリン酸 / ポルフィリン / 悪性神経膠腫 / HGF / FGF / 5-ALA … More / プロトポルフィリンIX / ABCG2 / がん幹細胞 / 5－アミノレブリン酸 / 5-アミノレブリン酸 / スペクトル解析 / グリオーマ / アミノレブリン酸 / 5-aminolevulinic acid / ５－アミノレブリン酸 / プロトポルフィリン / 組織内照射 / 一重項酸素 / 腫瘍幹細胞 / cerebral ischemia / mesenchymal stromal cell / bone marrow cell / Senescence accelerated mouse / Anti-aging / 老化促進マウス / 脳萎縮 / 骨髄細胞移植 / 老化 / 骨粗しょう症 / 認知症 / 遺伝子導入 / 脳梗塞治療 / 老化予防 / 脳虚血 / 骨髄間葉系幹細胞 / 骨髄細胞 / 老化マウス / アンチエイジング / Apoptosis / Robotic surgery / Reactive oxygen species / Photodynamic therapy / Spectroscopic analysis / Photodynamic diagnosis / Glioma / ロボット / 蛍光標識 / 分光解析 / センサー / 可視化 / 腫瘍 / アポトーシス / 手術ロボット / 活性酸素種 / 蛍光診断法 / 腫瘍可視化 / 分子デザイン / 5アミノレブリン酸 / 悪性脳腫瘍 / チロシンキナーゼ阻害薬 / 悪性グリオーマ / 神経膠芽腫 / リポソーム / 電子スピン共鳴法 / 音響力学療法 / 活性酸素 … More Except Principal Investigator 光線力学診断 / 悪性神経膠腫 / 脳腫瘍 / BNCT / herpes simplex virus / アミノレブリン酸 / GBM / transplantation / gene therapy / calponin / Therapeutic time window / glioma / Transferrin / SIMS / PET / BSH / BPA / vasculogenesis / neurogenesis / FGF-2 / cerebral infarction / bone marrow cell / vascular smooth muscle cell / common carotid artery / KHC rabbit / atherosclerosis / vasospasm / 5アミノレブリン酸 / 腫瘍可視化 / 手術ロボット / 光線力学療法 / ポルフィリン / 癌幹細胞 / 光線力学治療 / liposome / Neurosurgical operation / Cerebral blood blow / Brain edema / Coaxial laser exposure / YAG laser / CO2 laser / マイクロアンジオグラフィー / Nα / マイクロアンギオグラフィー / 脳血管 / 脳外科手術機械 / 同軸同時多種レーザー照射 / YAGレーザー / Nd / 血管の照射 / CO_2レーザー / 脳浮腫 / 微細脳血管 / 手術器具 / 血管内照射 / 脳外科手術 / ヤグレーザー / 炭酸ガスレーザー / Cooling filtrating system / Inta-arterial perfusion / Ringer solution / Cerebral hypothermia / Endovascular cooling / Acute cerebral ischemia / Brain cooling / brain hypothermia / acute cerebral ischemia / crystalloid perfusion / brain cooling / regional cerebral cooling / brain tissue oxygen tension / hemofiltration / rapid brain cooling / therapeutic time window / angiographical catheter / intra-arterial perfusion / selective cerebral hypothermia / cooling filtiration system / 動脈内潅流 / リンゲル液 / 低体温療法 / 血管内冷却 / 脳虚血 / 脳冷却 / meningioma / 5-aminolevulinic acid / Indocyanine green / fluorescence guided surgery / Near infer-red / Photodynamic diagnosis / 蛍光造影剤 / ナビゲーション手術 / 近赤外光 / 髄膜腫 / 神経膠腫 / インドシニアグリーン / 蛍光ガイド下手術 / 近赤外線 / transferin / TUMOR SENSOR / OPERATTON ROBOT / TUMOR VISUALIZATION / FLUORESCENCE GUIDE / BRAIN TUMOR / MALIGNANT GLIOMA / AMINOLEVULINIC ACID / PHOTODYNAMIC DIAGNOSIS / 自動制御 / 癌 / 腫瘍センサー / 蛍光ガイド / 血管平滑筋増殖 / 組み換えヘルペスウイルス / 攣縮血管 / 動脈硬化 / competent herpes virus / 悪性リンパ腫 / ５アミノレブリン酸 / ５－アミノレブリン酸 / 臨床応用 / バイオマーカー / 転写制御 / 光線力学診断法 / 代謝 / 遺伝子発現 / メタボローム解析 / トランスポーター / 5-アミノレブリン酸( ALA) / Nrf2 / ABCG2 / 5-アミノレブリン酸(ALA) / 悪性脳腫瘍 / 高LET放射線治療 / ほう素中性子捕捉療法 / 高ＬＥＴ粒子線 / グリオーマ幹細胞 / 粒子線 / X線 / 放射線 / 放射線抵抗性 / glioma stem cell / high LET / 神経膠芽腫 / 5-アミノレブリン酸 / スペクトル解析 / グリオーマ / Protocol / Transferin-PEG-Liposome / malignant meninigioma / malignant glioma / lipospme / スーパー特区 / 加速器 / 原子炉 / replication-competent / smooth muscle cell / replication-component / promoter / arteriosclerosis Less

Stereotactic interstitial photodynamic therapy of recurrent malignant glioma: phase I studyPrincipal Investigator
- Principal Investigator
  
  Kuroiwa Toshihiko
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka Medical and Pharmaceutical University
Innovation of 5-ALA photodynamic diagnosis and treatment in malignant glioma by drug discovery and molecular designPrincipal Investigator
- Principal Investigator
  
  Kuroiwa Toshihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka Medical College
Development of equipment for next generation 5-ALA photodynamic diagnosis and treatment
- Principal Investigator
  
  Kajimoto Yoshinaga
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka Medical College
Tumor-selective high LET and high RBE particles can overcome the radiation-resistant glioma stem cells
- Principal Investigator
  
  MIYATAKE Shin-Ichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Development of photodynamic therapy targeted at glioma stem cellsPrincipal Investigator
- Principal Investigator
  
  KUROIWA Toshihiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Photodynamic diagnosis of malignant brain tumor: analysis of molecular mechanisms and application to clinical diagnosis
- Principal Investigator
  
  ISHIKAWA Toshihisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnosis
- Research Institution
  The Institute of Physical and Chemical Research
Quantitative spectral analysis of 5-ALA derived porphyrin fluorescence and auto-fluorescence for improving PDDPrincipal Investigator
- Principal Investigator
  
  KUROIWA Toshihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Development of boron neutron capture therapy for the standard treatment of malignant brain tumors
- Principal Investigator
  
  MIYATAKE Shinichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Improvement of photodynamic diagnosis and therapy of brain tumors : Development of high power illumination system and sensing of distribution of photosensitizer
- Principal Investigator
  
  KAJIMOTO Yoshinaga
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Regeneration of neurons and vessels using bone marrow cells and gene deliveryPrincipal Investigator
- Principal Investigator
  
  KUROIWA Toshihiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Osaka Medical College
Development of fluorescence guided navigation system using a near infra-red fluorescent agent
- Principal Investigator
  
  KAJIMOTO Yoshinaga
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Rapid brain cooling method for acute cerebral ischemia・focal cerebral cooling by cold crystaloid intra-arterial perfusion in canine-
- Principal Investigator
  
  AOKI Atsushi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
悪性神経膠腫に対する次世代の光線・音響力学療法の開発Principal Investigator
- Principal Investigator
  
  黒岩敏彦
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Boron neutron capture therapy on malignant brain tumors.
- Principal Investigator
  
  MIYATAKE Shinichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
DEVELOPMENT OF SENSOR TYPE TUMOR RESECTION ROBOT SYSTEM
- Principal Investigator
  
  KAJIMOTO Yoshinaga
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  OSAKA MEDICAL COLLEGE
動脈硬化および臓器移植後血管狭窄に対する特異的複製可能型ウイルスによる遺伝子治療
- Principal Investigator
  
  MIYATAKE Shinichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Angiogenesis with bone marrow cells and gene therapy
- Principal Investigator
  
  MIYATAKE Shin-ichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Intra-operative identification of malignant glioma using real-time fluorescence spectroscopic analysis and double staining methodPrincipal Investigator
- Principal Investigator
  
  KUROIWA Toshihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Effect of herpes simplex virus vector, d12CALP, on vasospasm in rabbit common carotid artery with atherosclerotic changes
- Principal Investigator
  
  TAMURA Yoji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Osaka Medical College
Study on Combined CO2 and YAG Lasers in Neurosurgery - Application in the Cerebrovascular Operation
- Principal Investigator
  
  MATSUTAIRA Tsuyumu
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Medical and Dental University

[Book] 脳神経外科臨床マニュアル(改訂4版)(蛍光ガイド下手術)2010
- Author(s)
  梶本宜永、黒岩敏彦
- Publisher
  シュプリンガー・フェアラーク東京
- Data Source
  KAKENHI-PROJECT-20591729
[Book] 蛍光ガイド下手術.脳神経外科臨床マニュアル(改訂4版)2010
- Author(s)
  梶本宜永、黒岩敏彦
- Total Pages
  11
- Publisher
  シュプリンガー・フェアラーク東京
- Data Source
  KAKENHI-PROJECT-20591729
[Book] 新時代の脳腫瘍学-診断・治療の最前線-(術中蛍光診断)2010
- Author(s)
  梶本宜永、黒岩敏彦
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-20591729
[Book] 術中蛍光診断.新時代の脳腫瘍学-診断・治療の最前線-2010
- Author(s)
  梶本宜永、黒岩敏彦
- Total Pages
  7
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-20591729
[Book] 脳212009
- Author(s)
  宮武伸一、野々口直助、川端信司、黒岩敏彦
- Publisher
  Pseudoprogression"と「硼素中性子捕捉療法」
- Data Source
  KAKENHI-PROJECT-19390385
[Book] PDD and PDT for Malignant Glioma. The Biology of Glioma-A Discussion from the Standpoint of Photodynamic Diagnosis and Photodynamic Therapy2005
- Author(s)
  Kuroiwa T, Kajimoto Y, Miyatake S, Miyashita M.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17591537
[Book] PDD and PDT for Malignant Glcoma : The Biology of Glioma-A Discussion from the Standpoint of Photodynamic Diagnosis and Photodynamic Therapy2005
- Author(s)
  Kuroiwa T, Kajimoto Y, Miyatake S, Miyashita M
- Publisher
  springer
- Data Source
  KAKENHI-PROJECT-16659396
[Journal Article] The Characteristic of Light Sources and Fluorescence in the 3-Dimensional Digital Exoscope “ORBEYE” for 5-Aminolevulinic Acid?Induced Fluorescence-Guided Surgery Compared with a Conventional Microscope2022
- Author(s)
  Ikeda Naokado、Furuse Motomasa、Futamura Gen、Kimura Seigo、Nonoguchi Naosuke、Kawabata Shinji、Kameda Masahiro、Yokoyama Kunio、Takami Toshihiro、Kawanishi Masahiro、Kajimoto Yoshinaga、Kuroiwa Toshihiko、Wanibuchi Masahiko
- Journal Title
  
  World Neurosurgery
  
  Volume: 167 Pages: e1268-e1274
- DOI
  10.1016/j.wneu.2022.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10879
[Journal Article] Determination of Optical Properties of Human Brain Tumor Tissues From 350 to 1000 Nm to Investigate the Cause of False Negatives in Fluorescence-Guided Resection With 5-aminolevulinic Acid2019
- Author(s)
  Honda Norihiro, Katsunori Ishii, Yoshinaga Kajimoto, Toshihiko Kuroiwa, Kunio Awazu
- Journal Title
  
  J Biomed Opt.
  
  Volume: 23 Issue: 07 Pages: 1-10
- DOI
  10.1117/1.jbo.23.7.075006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10879
[Journal Article] Inhibition of human ABC transporter ABCG2 by gefitinib to enhance the efficacy of ALA-photodynamic therapy of brain tumor: learning from in vitro and in vivo experiments.2014
- Author(s)
  Inoue Y, Ikegami Y, Kajimoto Y, Kuroiwa T, Ishikawa T.
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: 1 Pages: 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] The roles of platelet-derived growth factors and their receptors in brain radiation necrosis2014
- Author(s)
  Miyata T, Toho T, Nonoguchi N, Furuse M, Kuwabara H, Yoritsune E, Kawabata S, Kuroiwa T, and Miyatake S
- Journal Title
  
  Radiation Oncology
  
  Volume: 9 Issue: 1 Pages: 51-59
- DOI
  10.1186/1748-717x-9-51
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592145, KAKENHI-PROJECT-23592146, KAKENHI-PROJECT-24659658, KAKENHI-PROJECT-26462192, KAKENHI-PROJECT-26462222
[Journal Article] The roles of Platelet-Derived Growth Factors and their receptors in brain radiation necrosis2014
- Author(s)
  Miyata T, Toho T, Nonoguchi N, Furuse M, Kuwabara H, Yoritsune E, Kawabata S, Kuroiwa T, and Miyatake S
- Journal Title
  
  Radiation Oncology
  
  Volume: 9 Pages: 51-51
- Data Source
  KAKENHI-PROJECT-23390355
[Journal Article] Boron neutron capture therapy with bevacizumab may prolong the survival of recurrent malignant glioma patients: four cases2014
- Author(s)
  Miyatake SI, Kawabata S, Hiramatsu R, Furuse M, Kuroiwa T, Suzuki M.
- Journal Title
  
  Radiation Oncology
  
  Volume: 9 Issue: 1 Pages: 6-11
- DOI
  10.1186/1748-717x-9-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592146, KAKENHI-PROJECT-24659658, KAKENHI-PROJECT-26462192, KAKENHI-PROJECT-26462222
[Journal Article] High linear-energy-transfer radiation can overcome radioresistance of glioma stem-like cells to low linear-energy-transfer radiation2014
- Author(s)
  Hirota Y, Masunaga SI, Kondo N, Kawabata S, Hirakawa H, Yajima H, Fujimori A, Ono K, Kuroiwa T, Miyatake SI
- Journal Title
  
  J Radiat Res
  
  Volume: 55(1) Pages: 75-83
- Data Source
  KAKENHI-PROJECT-23390355
[Journal Article] Boron neutron capture therapy with bevacizumab may prolong the survival of recurrent malignant glioma patients : four cases2014
- Author(s)
  Miyatake SI, Kawabata S, Hiramatsu R, Furuse M, Kuroiwa T, Suzuki M
- Journal Title
  
  Radiat Oncol
  
  Volume: 9(1) Pages: 6-6
- Data Source
  KAKENHI-PROJECT-23390355
[Journal Article] High linear-energy-transfer radiation can overcome radioresistance of glioma stem-like cells to low linear-energy-transfer radiation2014
- Author(s)
  Hirota Y, Masunaga S, Kondo N, et al. 計10名
- Journal Title
  
  J Radiat Res
  
  Volume: 55(1) Issue: 1 Pages: 75-83
- DOI
  10.1093/jrr/rrt095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300348, KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592146, KAKENHI-PROJECT-24659658
[Journal Article] Boron neutron capture therapy for recurrent high-grade meningiomas.2013
- Author(s)
  Kawabata S, Hiramatsu R, Kuroiwa T, Ono K, Miyatake SI.
- Journal Title
  
  J Neurosurg
  
  Volume: 119 Issue: 4 Pages: 837-844
- DOI
  10.3171/2013.5.jns122204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592146, KAKENHI-PROJECT-24659658
[Journal Article] Role of Nrf2 in cancer photodynamic therapy: regulation of human ABC transporter ABCG22013
- Author(s)
  Ishikawa Toshihisa, Kajimoto Yoshinaga, Sun Wei, Nakagawa Hiroshi, Inoue Yoji, Ikegami Yutaka, Miyatake Shin-Ichi, Kuroiwa Toshihiko
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 102 Issue: 9 Pages: 3058-3069
- DOI
  10.1002/jps.23563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592147, KAKENHI-PROJECT-23650619
[Journal Article] A surgical loupe system for observing protoporphyrin IX fluorescence in high-grade gliomas after administering 5-aminolevulinic acid2013
- Author(s)
  Kuroiwa Toshihiko, Kajimoto Yoshinaga, Furuse Motomasa, Miyatake Shin-Ichi
- Journal Title
  
  Photodiagnosis Photodynamic Therapy
  
  Volume: 10 Issue: 4 Pages: 379-381
- DOI
  10.1016/j.pdpdt.2013.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592147
[Journal Article] Identification of early and distinct glioblastoma response patterns treated by boron neutron capture therapy not predicted by standard radiographic assessment using functional diffusion map2013
- Author(s)
  Hiramatsu R, Kawabata S, Furuse M, Miyatake S, Kuroiwa T
- Journal Title
  
  Radiat Oncol
  
  Volume: 8(1) Pages: 192-192
- Data Source
  KAKENHI-PROJECT-23390355
[Journal Article] Bevacizumab treatment of symptomatic pseudoprogression after boron neutron capture therapy for recurrent malignant gliomas. Report of 2 cases2013
- Author(s)
  Miyatake SI, Furuse M, Kawabata S, Maruyama T, Kumabe T, Kuroiwa T, Ono K
- Journal Title
  
  Neuro Oncol
  
  Volume: 15(6) Pages: 650-5
- Data Source
  KAKENHI-PROJECT-23390355
[Journal Article] Identification of early and distinct glioblastoma response patterns treated by boron neutron capture therapy not predicted by standard radiographic assessment using functional diffusion map2013
- Author(s)
  Hiramatsu R, Kawabata S, Furuse M, Miyatake S, Kuroiwa T
- Journal Title
  
  Radiation Oncology
  
  Volume: 8 Issue: 1 Pages: 192-200
- DOI
  10.1186/1748-717x-8-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592146, KAKENHI-PROJECT-24659658
[Journal Article] Gefitinib enhances the efficacy of photodynamic therapy using 5-aminolevulinic acid in malignant brain tumor cells.2013
- Author(s)
  Sun Wei
- Journal Title
  
  Photodiagnosis Photodyn Ther
  
  Volume: 10 Issue: 1 Pages: 42-50
- DOI
  10.1016/j.pdpdt.2012.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592147, KAKENHI-PROJECT-23650619, KAKENHI-PROJECT-24659658
[Journal Article] Inhibition of human ABC transporter ABCG2 by gefitinib to enhanc e the efficacy of ALA-photodynamic thera py of brain tumor : learning from in vitro and in vivo experiments2013
- Author(s)
  Inoue Y, Ikegami Y, Kajimoto Y, Kuroiwa T, Ishikawa T
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: vol.1 Pages: 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Experimental study to understand nonspecific protoporphyrin IX fluorescence in brain tissues near tumors after 5-aminolevulinic acid administration2013
- Author(s)
  Masubuchi Takahiro, Kajimoto Yoshinaga, Kawabata Shinji, Nonoguchi Naosuke, Fujishiro Takahiro, Miyatake Shin-Ichi, Kuroiwa Toshihiko
- Journal Title
  
  Photomedicine and Laser Surgery
  
  Volume: 31 Issue: 9 Pages: 428-433
- DOI
  10.1089/pho.2012.3469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592147
[Journal Article] Bevacizumab Treatment for Symptomatic Radiation Necrosis Diagnosed by Amino Acid PET2013
- Author(s)
  Motomasa Furuse, Naosuke Nonoguchi, Shinji Kawabata1, Erina Yoritsune, Masatsugu Takahashi, Taisuke Inomata, Toshihiko Kuroiwa and Shin-Ichi Miyatake
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 43 Issue: 3 Pages: 337-341
- DOI
  10.1093/jjco/hys231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592145, KAKENHI-PROJECT-23592146, KAKENHI-PROJECT-24659658
[Journal Article] Gefitinib enhances the efficacy of photodynamic therapy using 5-aminolevulinic acid in malignant brain tumor cells2013
- Author(s)
  Wei Sun, Yoshinaga Kajimoto, Hiroto Inoue, Shin-Ichi Miyatake, Toshihisa Ishikawa, Toshihiko Kuroiwa
- Journal Title
  
  Photodiagnosis and photodynamic therapy
  
  Volume: 10 Pages: 42-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592147
[Journal Article] Symptomatic Radiation Necrosis Diagnosed by Amino Acid PET Motomasa Furuse2013
- Author(s)
  Naosuke Nonoguchi, Shinji Kawabata, Erina Yoritsune, Masatsugu Takahashi, Taisuke Inomata, Toshihiko Kuroiwa and Shin-Ichi Miyatake
- Journal Title
  
  Bevacizumab Treatment for Jpn J Clin Oncol
  
  Volume: 43(3) Pages: 337-41
- Data Source
  KAKENHI-PROJECT-23390355
[Journal Article] Boron neutron capture therapy for recurrent high-grade meningiomas2013
- Author(s)
  Kawabata S, Hiramatsu R, Kuroiwa T, Ono K, Miyatake SI
- Journal Title
  
  J Neurosurg
  
  Volume: 119(4) Pages: 837-44
- Data Source
  KAKENHI-PROJECT-23390355
[Journal Article] Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: the mechanism underlying 5-ALA-induced fluorescence in photodynamic diagnosis2011
- Author(s)
  Takahashi K, Ikeda N, Nonoguchi N, Kajimoto Y, Miyatake S, Hagiya Y, Ogura S, Nakagawa H, Ishikawa T, Kuroiwa T.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 13 Pages: 1234-1243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Transporter-Mediated Drug Interaction Strategy for 5-Aminolevulinic Acid (ALA)-Based Photodynamic Diagnosis of Malignant Brain Tumor: Molecular Design of ABCG2 Inhibitors2011
- Author(s)
  Ishikawa, Toshihisa Takahashi, Kenkichi Ikeda, Naokado Kajimoto, Yoshinaga Hagiya, Yuichiro Ogura, Shun-ichiro Miyatake, Shin-ichi Kuroiwa, Toshihiko
- Journal Title
  
  Pharmaceutics
  
  Volume: 3 Issue: 3 Pages: 615-635
- DOI
  10.3390/pharmaceutics3030615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592147
[Journal Article] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor: Molecular design of ABCG2 inhibitors.2011
- Author(s)
  Ishikawa T, Takahashi K, Ikeda N, Kajimoto Y, Hagiya Y, Ogura S, Miyatake S, Kuroiwa T.
- Journal Title
  
  Pharmaceutics
  
  Volume: 3 Pages: 615-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor : Molecular design of ABCG2 inhibitors2011
- Author(s)
  Ishikawa T, Takahashi K, Ikeda N, Kajimoto Y, Hagiya Y, Ogura S, Miyatake S, Kuroiwa T
- Journal Title
  
  Pharmaceutics
  
  Volume: vol.2 Pages: 615-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Key role of human ABC transporter ABCG2 in photodynamic therapy and photodynamic diagnosis2010
- Author(s)
  Ishikawa T, Nakagawa H, Hagiya Y,Nonoguchi N, Miyatake S, Kuroiwa T
- Journal Title
  
  Adv.Pharm.Sci. vol.10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591729
[Journal Article] Key role of human ABC transporter ABCG2 in photodynamic therapy and photodynamic diagnosis2010
- Author(s)
  Ishikawa T, Nakagawa H, Hagiya Y, Nonoguchi N, Miyatake S, Kuroiwa T
- Journal Title
  
  Adv.Pharm.Sci.
  
  Volume: 10(Epub) Pages: 2255-2255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591729
[Journal Article] 蛍光ガイド下手術2009
- Author(s)
  梶本宜永,黒岩敏彦
- Journal Title
  
  NS NOW vol.5
  
  Pages: 112-115
- Data Source
  KAKENHI-PROJECT-20591729
[Journal Article] Survival benefit of boron neutron capture therapy for recurrent malignant gliomas2009
- Author(s)
  Shin-Ichi Miyatake, Shinji Kawabata, Kunio Yokoyama, Toshihiko Kuroiwa, Hiroyuki Michiue, Yoshinori Sakurai, Hiroaki Kumada, Minoru Suzuki, Akira Maruhashi, Mitsunori Kirihata, Koji Ono
- Journal Title
  
  J Neuro-Oncol 91
  
  Pages: 199-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] Pseudoprogression in boron neutron capture therapy for malignant gliomas and meningiomas2009
- Author(s)
  Shin-Ichi Miyatake, Shinji Kawabata, Naosuke Nonoguchi, Kunio Yokoyama, Toshihiko Kuroiwa, Hideki Matsui and Koji Ono
- Journal Title
  
  Neuro-Onocology
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] 蛍光診断と外科的併用手術またはPDT併用治療での利点と問題点5-ALAによる光線力学診断における特異性、非特異性とメカニズム2009
- Author(s)
  梶本宜永、孫偉、高橋賢吉、池田直廉、野々口直助、宮武伸一、黒岩敏彦
- Journal Title
  
  日本レーザー医学会誌 vol.30
  
  Pages: 335-335
- Data Source
  KAKENHI-PROJECT-20591729
[Journal Article] Boron neutron capture therapy for newly diagnosed glioblastoma2009
- Author(s)
  Shinji Kawabata, Shin-Ichi Miyatake, Toshihiko Kuroiwa, Kunio Yokoyama, Atsushi Doi, Kyoko Iida, Shiro Miyata, Naosuke Nonoguchi, Hiroyuki Michiue, Masatsugu Takahashi, Taisuke Inomata, Yoshio Imahoti, Mitsunori Kirihata, Yoshinori Sakurai, Akira Maruhashi, Hiroaki Kumada, and Koji Ono
- Journal Title
  
  J Rad Res 50
  
  Pages: 51-60
- NAID
  110007042075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] 蛍光ガイド下手術2009
- Author(s)
  梶本宜永, 黒岩敏彦
- Journal Title
  
  NSNOWグリオーマその最新知見 5
  
  Pages: 112-115
- Data Source
  KAKENHI-PROJECT-20591729
[Journal Article] Intraoperative photo-dynamic diagnosis of brain tumors.2009
- Author(s)
  Miyatake S, Kajimoto Y, Kuroiwa
- Journal Title
  
  vol.61
  
  Pages: 835-842
- NAID
  40016747533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591729
[Journal Article] 蛍光ガイド下手術2009
- Author(s)
  梶本宜永, 黒岩敏彦
- Journal Title
  
  NSNOWグリオーマその最新知見 5
  
  Pages: 112-115
- Data Source
  KAKENHI-PROJECT-19591709
[Journal Article] Evaluation of Fluoride-labeled Boronophenylalanine-PET Imaging for the Study of Radiation Effects in Patients with Malignant Gliomas2008
- Author(s)
  Minoru Miyashita, Shin-Ichi Miyatake, Yoshio Imahori, Kunio Yokoyama, Shinji Kawabata, Yoshinaga Kajimoto, Masa-Aki Shibata, Yoshinori Otsuki, Mitsunori Kirihata, Koji Ono, and Toshihiko Kuroiwa
- Journal Title
  
  J Neuro-Oncol 89(2)
  
  Pages: 239-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] Planned fractionated boron neutron capture therapy using epithermal neutrons for a patient with recurrent squamous cell carcinoma in the temporal bone : a case report2008
- Author(s)
  Shin-Ichi Haginomori, Shin-Ichi Miyatake, Takaki Inui, Michitosi Araki, Shinji Kawabata, Atsuko Takamaki, Koutetsu Lee, Hiroshi Takenkaka, Toshihiko Kuroiwa, Yasuo Uesugi, Hiroaki, Kumada, Koji Ono
- Journal Title
  
  Head and Neck 31
  
  Pages: 412-418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] Tumor-specific targeting of sodium borocaptate (BSH) to malignant glioma by transferrin-PEG liposomes for boron neutron capture therapy2008
- Author(s)
  Atsushi Doi, Kyoko Iida, Kunio Yokoyama, Shinji Kawabata, Yoshinaga Kajimoto, Toshihiko Kuroiwa, Takashi Shirakawa, Mitsunori Kirihata, Satoshi Kasaoka, Kazuo Maruyama, Yoshinori Sakurai, Shin-Ichiro Masunaga, Koji Ono and Shin-Ichi Miyatake
- Journal Title
  
  J Neurooncol 87(3)
  
  Pages: 287-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] Fluorescence of non-neoplastic, magnetic resonance imaging-enhancing tissue by 5-aminolevulinic acid: case report.2007
- Author(s)
  Miyatake S, Kuroiwa T, Kajimoto Y, Miyashita M, Tanaka H, Tsuji M.
- Journal Title
  
  Neurosurgery Vol.65,No.5
  
  Pages: 1101-1104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591709
[Journal Article] Endoscopic identification and biopsy sampling of an intraventricular malignant glioma using a 5-aminolevulinic acid-induced protoporphyrin IX fluorescence imaging system. Technical note2007
- Author(s)
  Tamura Y, Kuroiwa T, Kajimoto Y, Miki Y, Miyatake s, Tsuji M
- Journal Title
  
  J Neurosurg 106・3
  
  Pages: 507-510
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Endoscopic identification and biopsy sampling of an intraventricular malignant glioma using a 5-aminolevulinic acid-induced protoporphyrin IX fluorescence imaging system. Technical note2007
- Author(s)
  Tamura Y, Kuroiwa T, Kajimoto Y, Miki Y, Miyatake S, Tsuji M
- Journal Title
  
  J Neurosurg 106・3
  
  Pages: 507-510
- Data Source
  KAKENHI-PROJECT-16659396
[Journal Article] Fluorescence-guided resection of meningioma with high risk of recurrence using 5-aminolevulinic acid2007
- Author(s)
  Kajimoto Y, Kuroiwa T, Miyatake S, Ichioka T, Miyashita M, Tanaka H, Tsuji M
- Journal Title
  
  J Neurosurgery 107 (2) (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Fluorescence-guided resection of meningioma with high risk of recurrence using 5-aminolevulinic acid2007
- Author(s)
  Kajimoto Y, Kuroiwa T, Miyatake S, Ichioka T, Miyashita M, Tanaka H, Tsuji M
- Journal Title
  
  J Neurosurgery 107(2)(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Boron neutron capture therapy for malignant tumors related to meninigiomas2007
- Author(s)
  Shin-Ichi Miyatake, Yoji Tamura, Shinji Kawabata, Toshihiko Kuroiwa, and Koji Ono
- Journal Title
  
  Neurosurgery 61
  
  Pages: 82-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] Endoscopic identification and biopsy sampling of an intraventricular malignant glioma using a 5-aminolevulinic acid-induced protoporphyrin IX fluorescence imaging system. Technical note2007
- Author(s)
  Tamura Y, Kuroiwa T, Kajimoto Y, Miki Y, Miyatake S, Tsuji M
- Journal Title
  
  J Neurosurgery 106(3)
  
  Pages: 507-510
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Use of 5-aminolevulinic acid in fluorescence-guided resection of meningioma with high risk of recurrence. Case report.2007
- Author(s)
  Kajimoto Y, Kuroiwa T, Miyatake S, Ichioka T, Miyashita M, Tanaka H, Tsuji M.
- Journal Title
  
  J Neurosurg vol.106、No.6
  
  Pages: 1070-1074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591709
[Journal Article] Fluorescence of non-neoplastic, MRI-enhancing tissue by 5-aminolevulenic acid : Report of 3 cases2007
- Author(s)
  Miyatake S, Kuroiwa T, Kajimoto Y, Miyashita M, Tanaka H, Tsuji M
- Journal Title
  
  Neurosurgery 61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390385
[Journal Article] Fluorescence-guided resection of meningioma with high risk of recurrence using 5-aminolevulinic acid2007
- Author(s)
  Kajimoto Y, Kuroiwa T, Miyatake S, Ichioka T, Miyashita M, Tanaka H, Tsuji M
- Journal Title
  
  J Neurosurg (In print)
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Massive apoptotic cell death of human glioma cells via a mitochondrial pathway following 5-aminolevulinic acid-mediated photodynamic therapy2007
- Author(s)
  Inoue H, Kajimoto Y, Shibata MA, Miyoshi N, Ogawa N,, Miyatake SI, Otsuki Y,, Kuroiwa T
- Journal Title
  
  J Neurooncol
- Data Source
  KAKENHI-PROJECT-16659396
[Journal Article] Fluorescence-guided resection of meningioma with high risk of recurrence using 5-aminolevulinic acid2007
- Author(s)
  Kajimoto Y, Kuroiwa T, Miyatake S, Ichioka T, Miyashita M, Tanaka H, Tsuji M
- Journal Title
  
  J Neurosurg (In print)
- Data Source
  KAKENHI-PROJECT-16659396
[Journal Article] Massive apoptotic cell death of human glioma cells via a mitochondrial pathway following 5-aminolevulinic acid-mediated photodynamic therapy2007
- Author(s)
  Inoue H, Kajimoto Y, Shibata MA, Miyoshi N, Ogawa N, Miyatake SI, Otsuki Y, Kuroiwa T
- Journal Title
  
  J Neurooncol (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] 脳腫瘍における光線力学療法2006
- Author(s)
  梶本宜永, 宮武伸一, 黒岩敏彦
- Journal Title
  
  脳神経外科速報 16・4
  
  Pages: 331-338
- Data Source
  KAKENHI-PROJECT-16659396
[Journal Article] Novel Therapeutic Strategy for Stroke in Rats by Bone Marrow Stromal Cells and Ex Vivo HGF Gene Transfer with HSV-1 Vector2006
- Author(s)
  M Zhao, N Nonoguchi, N Ikeda, T Watanabe, D Furutama, D Miyazawa, H Funakoshi, Y Kajimoto, T Nakamura, M Dezawa, M Shibata, Y Otsuki, RS. Coffin, W Liu, T Kuroiwa, S Miyatake
- Journal Title
  
  J Cereb Blood Flow Metab 26・9
  
  Pages: 1176-1188
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300224
[Journal Article] Novel Therapeutic Strategy for Stroke in Rats by Bone Marrow Stromal Cells and Ex Vivo HGF Gene Transfer with HSV-1 Vector2006
- Author(s)
  M Zhao, N Nonoguchi, N Ikeda, T Watanabe, D Furutama, D Miyazawa, H Funakoshi, Y Kajimoto, T Nakamura, M Dezawa, M Shibata, Y Otsuki, RS. Coffin, W Liu, T Kuroiwa, S Miyatake
- Journal Title
  
  J Cereb Blood Flow Metab 26 (9)
  
  Pages: 1176-1188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300224
[Journal Article] 脳腫瘍における光線力学療法2006
- Author(s)
  梶本宜永, 宮武伸一, 黒岩敏彦
- Journal Title
  
  脳神経外科速報 X
  
  Pages: 57-65
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Bone Marrow Stromal Cells That Enhanced FGF-2 Secretion by Herpes Simplex Virus Vector Improve Neurological Outcome after Transient Focal Cerebral Ischemia in Rats.2005
- Author(s)
  Ikeda N, Nonoguchi N, Zhao MZ, Watanabe T, Kajimoto Y, Furutama D, Kimura F, Dezawa M, Robert S, Otsuki Y, Kuroiwa T, Miyatake SI
- Journal Title
  
  Stroke 36・12
  
  Pages: 2725-2730
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300224
[Journal Article] Glioma surgery in a motor area using a combination of intraoperative subcortical stimulation and 5-aminolevulinic acid-induced tumor fluorescence2005
- Author(s)
  Aoki A, Kuroiwa T, Yasuda S, Furuse M, Kajimoto Y, Miyatake S
- Journal Title
  
  13th World Congress of Neurological Surgery
  
  Pages: 43-47
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Glioma surgery in a motor area using a combination of intraoperative subcortical stimulation and 5-aminolevulinic acid-induced tumor fluorescence2005
- Author(s)
  Aoki A, Kuroiwa T, Yasuda S, Furuse M, Kajimoto Y, Miyatake S
- Journal Title
  
  13th World Congress of Neurological Surgery 43-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] The Biology of Glioma-A Discussion from the Standpoint of Photodynamic Diagnosis and Photodynamic Therapy2005
- Author(s)
  Kuroiwa T, Kajimoto Y, Miyatake S, Miyashita M
- Journal Title
  
  PDD and PDT for Malignant Glioma
  
  Pages: 80-84
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] The Biology of Glioma-A Discussion from the Standpoint of Photodynamic Diagnosis and Photodynamic Therapy2005
- Author(s)
  Kuroiwa T, Kajimoto Y, Miyatake S, Miyashita M.
- Journal Title
  
  PDD and PDT for Malignant Glioma 80-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591537
[Journal Article] Bone Marrow Stromal Cells That Enhanced FGF-2 Secretion by Herpes Simplex Virus Vector Improve Neurological Outcome after Transient Focal Cerebral Ischemia in Rats.2005
- Author(s)
  Ikeda N, Nonoguchi N, Zhao MZ, Watanabe T, Kajimoto Y, Furutama D, Kimura F, Dezawa M, Robert S, Otsuki Y, Kuroiwa T, Miyatake SI
- Journal Title
  
  Stroke 36 (12)
  
  Pages: 2725-2730
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300224
[Journal Article] Fiber-optic spectroscopic detection of neoplasm by intraoperative fluorescence labeling.2004
- Author(s)
  Y Kajimoto, T Kuroiwa et al.
- Journal Title
  
  International Congress Series 1259
  
  Pages: 33-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500351
[Journal Article] Fiber-optic spectroscopic detection of neoplasm by inlraoperative fluorescence labeling2004
- Author(s)
  Y Kajimoto, T Kuroiwa et al.
- Journal Title
  
  International Congress Series 1259
  
  Pages: 33-38
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500351
[Journal Article] Fiber-optic spectroseopic detection of neoplasm by intraoperative fluorescepce labeling2004
- Author(s)
  Y Kajimoto, T Kuroiwa et al.
- Journal Title
  
  International Congress Series 1259
  
  Pages: 33-38
- Data Source
  KAKENHI-PROJECT-15500351
[Journal Article] 蛍光標識手術2003
- Author(s)
  黒岩敏彦, 梶本宜永ら
- Journal Title
  
  Clinical Neuroscience 21
  
  Pages: 584-585
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500351
[Patent] 治療抵抗性がんの予防又は治療用組成物2014
- Inventor(s)
  石川智久, 黒岩敏彦, 梶本宜永, 藤城高広, 木村誠吾, 宮武伸一, 田中徹
- Industrial Property Rights Holder
  理化学研究所, 大阪医科大学, SBIファーマ株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-031220
- Filing Date
  2014-02-21
- Data Source
  KAKENHI-PROJECT-23650619
[Patent] 治療抵抗性がんの予防用又は治療用組成物2014
- Inventor(s)
  石川智久、黒岩敏彦、梶本宜永　他
- Industrial Property Rights Holder
  理化学研究所、大阪医科大学、SBIファーマ株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-031220
- Filing Date
  2014-02-21
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 5-Aminolevulinic Acid (ALA)-Based Photodynamic Therapy of Malignant Brain Tumors and Glioma Stem Cells : From Basic Research to Clinical Applications of an ABCG2 Inhibitor2014
- Author(s)
  Ishikawa T, Fujishiro T, Kajimoto Y, Inoue Y, Ikegami Y, Kuroiwa T
- Organizer
  FEBS ATP-Binding Cassette (ABC) Proteins
- Place of Presentation
  オーストリア Innsbruck
- Year and Date
  2014-03-12
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 脳腫瘍に対する光線力学診断（PDD）と光線力学治療（PDT）2014
- Author(s)
  黒岩敏彦、梶本宜永
- Organizer
  CNTT
- Place of Presentation
  ヒルトン福岡シーホーク
- Invited
- Data Source
  KAKENHI-PROJECT-23592147
[Presentation] 癌の光線力学治療におけるNrf2の役割 : ABCG2遺伝子の発現調節2013
- Author(s)
  石川智久, 梶本宜永, Wei Sun , 井上裕貴, 池上洋二, 萩谷祐一郎, 小倉俊一郎, 宮武伸一, 黒岩敏彦
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  横浜
- Year and Date
  2013-04-27
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2 阻害剤のデザイン2013
- Author(s)
  井上裕貴, 池上洋二, 佐野和美, 小金井美穂, 吉田久博, 藤城高広, 木村誠吾, 深見竹広, 梶本宜永, 宮武伸一, 黒岩敏彦, 石川智久
- Organizer
  ポルフィリンALA 学会
- Place of Presentation
  横浜
- Year and Date
  2013-04-27
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2 の役割 : ABCG2 遺伝子発現の制御2013
- Author(s)
  石川智久, 井上裕貴, 池上洋二, 中川大, 黒岩敏彦
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  東京
- Year and Date
  2013-10-10
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] The role of Nrf2 in photodynamic therapy : Regulation of ABCG2 gene expression2013
- Author(s)
  Ishikawa T, Kajimoto Y, Inoue Y, Ikegami Y, Nakagawa Y, Kuroiwa T
- Organizer
  日本生化学会2013年次大会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2013-10-02
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 脳腫瘍幹細胞様細胞に対する5-ALA PDT 感受性の評価2013
- Author(s)
  藤城高広, 梶本宜永, 木村誠吾, 宮武伸一, 石川智久, 黒岩敏彦
- Organizer
  ポルフィリンALA 学会
- Place of Presentation
  横浜
- Year and Date
  2013-04-27
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン2013
- Author(s)
  井上裕貴, 池上洋二, 佐野和美, 黒岩敏彦, 石川智久
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  東京
- Year and Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 脳腫瘍幹細胞様細胞に対する 5-ALA PDT感受性評価2013
- Author(s)
  藤城高広, 梶本宜永, 木村誠吾, 宮武伸一, 石川智久, 黒岩敏彦
- Organizer
  第3回　ポルフィリンALA学会
- Place of Presentation
  東京工業大学　すずかけ台キャンパス　すずかけホール
- Data Source
  KAKENHI-PROJECT-23592147
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン2013
- Author(s)
  井上裕貴, 池上洋二, 佐野和美, 黒岩敏彦, 石川智久
- Organizer
  日本癌学会2013年総会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2013-10-02
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor: Molecular design of ABCG2 inhibitors2012
- Author(s)
  Toshihisa Ishikawa, Kenkichi Takahashi, Naokado Ikeda, Yoshinaga Kajimoto, Yuichiro Hagiya, Shun-ichiro Ogura, Hikaru Saito, Shin-ichi Miyatake, and Toshihiko Kuroiwa
- Organizer
  International Symposium on PPF Molecular Pharmacokinetics
- Place of Presentation
  一橋記念講堂（東京）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor : Molecular design of ABCG2 inhibitors2012
- Author(s)
  Ishikawa T, Takahashi K, Ikeda N, Kajimoto Y, Hagiya Y, Ogura S, Saito H, Miyatake S-I, Kuroiwa T
- Organizer
  薬物動態国際シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor : molecular design of ABCG2 inhibitors2012
- Author(s)
  Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T., Ishikawa, T
- Organizer
  International Forum "Patients and Medicines"
- Place of Presentation
  横浜
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor: molecular design of ABCG2 inhibitors2012
- Author(s)
  Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T., Ishikawa, T.
- Organizer
  International Forum “Patients and Medicines"
- Place of Presentation
  理化学研究所（横浜）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 5-Aminolevulinic Acid (ALA)-based photodynamic diagnosis of malignant brain tumor : Molecular design of ABCG2 inhibitors2012
- Author(s)
  Ishikawa T., Kuroiwa T
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Molecular fluorescence imaging to assist neurosurgery of malignant brain tumors in humans : from bench to bedside2011
- Author(s)
  Ishikawa, T., Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Molecular fluorescence imaging to assist neurosurgery of malignant brain tumors in humans: from bench to bedside2011
- Author(s)
  Ishikawa, T., Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T.
- Organizer
  13th Japanese-German Cancer Workshop(招待講演)
- Place of Presentation
  グランドプリンスホテル広島（広島）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Gefitinibによる細胞内PpIXの細胞外輸送の阻害効果2009
- Author(s)
  孫偉, 梶本宜永, 宮武伸一, 黒岩敏彦
- Organizer
  第68回日本脳神経外科学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-19591709
[Presentation] アミノレブリン酸(5-ALA)による脳腫瘍の蛍光機序について2009
- Author(s)
  高橋賢吉, 池田直廉, 梶本宜永, 宮武伸一, 黒岩敏彦
- Organizer
  第68回日本脳神経外科学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-19591709
[Presentation] 転移性脳腫瘍における5-ALA蛍光ガイド手術2008
- Author(s)
  梶本宜永, 鱒渕誉宏, 宮下実, 田中秀一, 青木淳, 田村陽史, 宮武伸一, 黒岩敏彦
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19591709
[Presentation] 非腫瘍性病変もPpIXの蛍光を発する2008
- Author(s)
  宮武伸一, 梶本宜永, 宮下実, 田中秀一, 鱒渕誉宏, 黒岩敏彦
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19591709
[Presentation] 蛍光診断とグリオーマ手術2007
- Author(s)
  黒岩敏彦, 梶本宜永, 宮武伸一
- Organizer
  第27回日本脳神経外科コングレス総会
- Place of Presentation
  仙台サンプラザ(宮城)
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19591709
[Presentation] 次世代の5-ALA蛍光ガイドシステム-高出力LED光源とインテリジェント超音波メス2007
- Author(s)
  梶本宜永, 鱒渕誉宏, 青木淳, 田村陽史, 宮武伸一, 黒岩敏彦
- Organizer
  第66回日本脳神経外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪(東京)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591709
[Presentation] 癌の光線力学治療におけるNrf2の役割：ABCG2遺伝子発現の制御
- Author(s)
  石川智久、井上裕貴、池上洋二、中川大、黒岩敏彦
- Organizer
  日本癌学会2013年総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 脳腫瘍幹細胞様細胞に対する5-ALA PDT感受性の評価
- Author(s)
  藤城高広、梶本宜永、木村誠吾、宮武伸一、石川智久、黒岩敏彦
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  東京工業大学すずかけ台キャンパス
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン
- Author(s)
  井上裕貴、池上洋二、佐野和美、小金井美穂、吉田久博、藤城高広、木村誠吾、深見竹広、梶本宜永、宮武伸一、黒岩敏彦、石川智久
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  東京工業大学すずかけ台キャンパス
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 5-Aminolevulinic Acid (ALA)-based photodynamic diagnosis of malignant brain tumor: Molecular design of ABCG2 inhibitors
- Author(s)
  Ishikawa T., Kuroiwa T.
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2の役割：ABCG2遺伝子発現の制御
- Author(s)
  石川智久、井上裕貴、池上洋二、中川大、黒岩敏彦
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  タワーホール船堀, 東京
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 5-Aminolevulinic Acid (ALA)-Based Photodynamic Therapy of Malignant Brain Tumors and Glioma Stem Cells: From Basic Research to Clinical Applications of an ABCG2 Inhibitor
- Author(s)
  Ishikawa T, Fujishiro T, Kajimoto Y, Inoue Y, Ikegami Y, Kuroiwa T.
- Organizer
  FEBS ATP-Binding Cassette (ABC) Proteins
- Place of Presentation
  Hotel Grauer Baer, Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン
- Author(s)
  井上裕貴、池上洋二、佐野和美、黒岩敏彦、石川智久
- Organizer
  日本癌学会2013年総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2の役割：ABCG2遺伝子の発現調節
- Author(s)
  石川智久、梶本宜永、Wei Sun 、井上裕貴、池上洋二、萩谷祐一郎、小倉俊一郎、宮武伸一、黒岩敏彦
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  東京工業大学すずかけ台キャンパス
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] The role of Nrf2 in photodynamic therapy: Regulation of ABCG2 gene expression
- Author(s)
  Ishikawa T, Kajimoto Y, Inoue Y, Ikegami Y, Nakagawa Y, Kuroiwa Y
- Organizer
  日本生化学会 2013年次大会
- Place of Presentation
  パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン
- Author(s)
  井上裕貴、池上洋二、佐野和美、黒岩敏彦、石川智久
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  タワーホール船堀, 東京
- Data Source
  KAKENHI-PROJECT-23650619

1. KAJIMOTO Yoshinaga (30224413)

# of Collaborated Projects: 14 results

# of Collaborated Products: 51 results
2. MIYATAKE Shinichi (90209916)

# of Collaborated Projects: 10 results

# of Collaborated Products: 37 results
3. ONO Koji (90122407)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
4. KIRIHATA Mitsunori (60128767)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. ISHIKAWA Toshihisa (60193281)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
6. AOKI Astushi (90319559)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. DEGUCHI Jun (00288713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KAWABATA Shinji (20340549)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
9. MATSUI Hideki (30157234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. KASAOKA Satoshi (90338690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MICHIUE Hiroyuki (20572499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MASUNAGA Shin-ichirou (80238914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. OGURA Shun-ichiro (90343160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
14. TAMURA Yoji (90247859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YOSHIDA Toshiko (00171421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NONOGUCHI Naosuke (70388263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. DEZAWA Mari (50272323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. FURUSE Motomasa (70340560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MATSUTAIRA Tsuyumu (50014345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TONE Osamu (70188762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 堀本仁士 (70247849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 上田陽彦 (80176594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 林道広 (90314179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中村英夫 (30359963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 丸山一雄 (30130040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 鬼頭清裕 (30177878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 青柳昌樹 (60175750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 田畑均 (80138479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 清田満

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. MASAOKA Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. YAMAZAKI Shingo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kuroiwa Toshihiko 黒岩 敏彦

KUROIWA Toshihiko 黒岩 敏彦

黒岩 俊彦 クロイワ トシヒコ

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Stereotactic interstitial photodynamic therapy of recurrent malignant glioma: phase I studyPrincipal Investigator

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Innovation of 5-ALA photodynamic diagnosis and treatment in malignant glioma by drug discovery and molecular designPrincipal Investigator

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Development of photodynamic therapy targeted at glioma stem cellsPrincipal Investigator

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Quantitative spectral analysis of 5-ALA derived porphyrin fluorescence and auto-fluorescence for improving PDDPrincipal Investigator

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Regeneration of neurons and vessels using bone marrow cells and gene deliveryPrincipal Investigator

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悪性神経膠腫に対する次世代の光線・音響力学療法の開発Principal Investigator

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Kuroiwa Toshihiko 黒岩敏彦

KUROIWA Toshihiko 黒岩敏彦

黒岩俊彦クロイワトシヒコ