KOMIYA Setsurou 小宮節郎

Researcher Number	30178371
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015 – 2019: 鹿児島大学, 医歯学域医学系, 教授 2014: 鹿児島大学, 医歯学総合研究科, 教授 2013 – 2014: 鹿児島大学, 大学院医歯学総合研究科, 教授 2011 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 教授 2012: 鹿児島大学, 医学部, 教授 … More 2011 – 2012: 鹿児島大学, 大学院・医歯学総合研究科, 教授 2010 – 2012: Kagoshima University, 医歯学総合研究科, 教授 2007 – 2009: Kagoshima University, Graduate School of Medical and Dental Sciences, Professor 2005 – 2006: Kagoshima Graduate School of Medical and Dental Sciences, Professor, 大学院医歯学総合研究科, 教授 2003 – 2005: KAGOSHIMA UNIVERSITY, GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES, PROFESSOR, 大学院・医歯学総合研究科, 教授 1999 – 2003: 鹿児島大学, 医学部, 教授 1995 – 1998: 久留米大学, 医学部, 講師 1992: Dept. of Orthopedics Kurume Med.school Lecturer, 医学部・整形外科, 講師 1992: 久留米大学, 医学部整形外科, 講師 1991: 久留米大学, 整形外科, 講師 1990: 久留米大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery / Surgical dentistry / Pediatrics
Keywords	Principal Investigator 骨肉腫 / Cbl / Src / Signal transduction / 細胞内情報伝達 / Fas / osteosarcoma / CD44 / 破骨細胞 / 肺転移 … More / 関節リウマチ / Rheumatoid arthritis / c-Cbl / ユビキチン / 骨吸収 / Pulmonary metastasis / adenovirus / Cytokine / Interleukin 2 / Gene therapy / Chimera vector / アデノウイルスベクター / 自殺遺伝子 / アデノウイルス / サイトカイン / インターロイキン2 / 遺伝子治療 / キメラベクター / Apoptosis / Soluble Fas / Giant cell tumor (GCT) / Osteosarcoma (OSA) / アポトーシス / soluble Fas / 骨巨細胞腫 / metastasismalignancy / hyaluronic acid / MMP / 骨肉種 / 悪性 / 転移 / ヒアルロン酸 / Osteoclast / Matrix-metalloproteinase / Basement membrane / Soft part tumor / Bone tumor / Metastasis / 骨吸収活性 / コラーゲン分解能 / 基底膜 / 軟部腫瘍 / 骨腫瘍 / 骨融解 / ポリエチレン摩耗 / 好中球 / 人工関節周囲感染 / 感染 / オートファジー / 人工関節ルーズニング / 軟部肉腫 / 外科系臨床医学・整形外科学 / GOLPH3L / GOLPH3 / 横紋筋肉腫 / EZH2 / BMI-1 / EZH2,BMI-1 / ポリコーム蛋白 / sarcoma-initiating cells / sarcoma-initiating cell / がん幹細胞 / 骨軟部肉腫 … More Except Principal Investigator 骨肉腫 / 軟骨細胞 / 骨芽細胞 / 軟骨細胞分化 / TGF-β / Hedgehog / アポトーシス / 脊髄損傷 / p21 / 軟骨肉腫 / BMP / 変形性関節症 / GLI2 / 転移 / 骨軟部腫瘍 / 後縦靭帯骨化症 / OPLL / Apoptosis / ヒアルロン酸 / differentiation / 骨芽細胞分化 / 骨軟部肉腫 / osteosarcoma / 細胞周期 / Notch / 癌 / FOSL1 / HDAC阻害剤 / LBH589 / UPS / 未分化多型肉腫 / GWAS / GADD45beta / ubiquitin system / signal transduction / 抑制因子 / シグナル伝達 / c-Cbl / 蛋白分解系 / HMGB-1 / エリスロポエチン / 急性脊髄損傷 / apoptosis / 細胞内シグナル伝達 / 脊椎後縦靭帯骨化症 / 分子生物学 / Osteoporosis / sFRPs / CD44 / 骨肉腫細胞 / Smpd3 / PEG10 / RPS3 / iPS細胞 / osteoblast / chondrocyte / SnoN / OA / 低酸素 / 抗癌剤 / 遺伝子治療 / 横紋筋肉腫 / 神経変性 / 老化 / オートファジー / 老化促進マウス / 遺伝子 / 分子標的 / 未分類肉腫 / 未分化肉腫 / ＵＰＳ / SR48692 / Neurotensin Receptor 1 / FOS-like antigen 1 / 尿素輸送体 / 尿素 / UT-B / SLC14A1 / WNT / CDC5L / 内軟骨性骨化 / Stk38l / セリン・スレオニン・キナーゼ / STK38L / 軟部肉腫 / HDAC inhibitor / 未分化多形肉腫 / 整形外科 / Atoh8 / 抗癌剤デリバリー / デリバリー / Tranilast / アンジオテンシン経路 / 細胞外マトリックス / 靭帯細胞 / 脊柱後縦靭帯骨化症 / Hypertrophic chondrocyte / osteoarthritis / マウス / GADD45b / 肥大軟骨細胞 / Hyaluronic acid / sMSF protein / Rheumatoid Arthritis / Lubricin / 免疫学 / 蛋白質 / sMSFタンパク / 関節リウマチ / lubricin / hyaluronan / inhibitor / osteoclast / Cbl / Src / 破骨細胞 / negative regulation / bisphosphonate / 遺伝子導入 / 増殖抑制 / ビスホスホネート / Erythropoietin / Spinal Cord Injury / HMGB1 / spinal cord degeneration / erythropoietin / spinal cord injury / intercellular signaling / cytokines / intervertebral disc / senescence-accelerated mice / 髄核細胞 / 変性 / 細胞内情報伝達 / サイトカイン / 椎間板 / siRNA / hMSC / Wntパスウェイ / RNAi / 遺伝子発現 / マイクロアレイ / 間葉系幹細胞 / BMP4 / cDNA / 脊椎後縦靱帯骨化症 / コラーゲン11A2 / 11型コラーゲン / 罹患同胞対 / 連鎖解析 / 骨化 / 脊椎後縦靱帯 / BMP-4 / ゲノム解析 / Secreted frizzled related protein / Monocyte / 骨形態計測 / Secreted related protein / 骨粗鬆症 / merastasis / chemoraxis / osteosarcoma sells / 細胞運動性 / IGF-I / PTHrP / chondrosarcoma / P21 / PTHrT / IGF-1 / 分化 / Vitamin K / Vitamin D / osteosarcoma cells / 細胞内伝達 / セレニウム / ビタミンK / ビタミンD / 分化誘導 / c-MYC / MYCT1 / c-Myc / TGF-βシグナル / Myct1 / BMPシグナル / 軟骨細胞成熟 / 鑑別分子マーカー / 分化度 / TGF-b / 内軟骨腫 / 三酸化ヒ素 / metastasis / 浸潤 / MMP9 / NOTCH / 肺転移 / HEY1 / RBPJ / がん幹細胞 / サバイビン / ヘッジホッグ経路 / Adenovirus / ヘッジホッグシグナル / 慢性圧迫性脊髄障害 / 神経幹細胞 / 再生 / 幹細胞移植 / 再生治療 / 霊長類 / Schnurri3 / シュニュリ3 / Runx2 / Alg2 / Hivep3 / Shn3 / TGF-beta / TGF-beta, Sweden / 関節軟骨 / 石灰化 / 肥大化 / 軟骨 / C/EBPbeta / Gadd45beta / C/EBPβ / GADD45β / 関節病学 / 低酸素環境(Hypoxia) / 上皮間葉移行(EMT) / 口腔癌 / EMT / 口腔扁平上皮癌 / Notchシグナル / 細胞浸潤 / 細胞増殖 / Hedgehog Smoothened / デリバリーシステム / ドラッグデリバリーシステム / マイクロバブル / 超音波 / 有害事象 / 化学療法 / ウイルスベクター / Fibroblast growth factor receptor 3 / Fibroblast growth factor recetor3 / 肉腫幹細胞 / Hedgehog, Sarcoma-initiating cell / 腫瘍幹細胞 / 運動療法 / NO / Beclin / 関節軟骨変性 / トレッドミル運動 / 脊髄前角細胞 / ベクリン / 脊髄変性 / 加齢 / 運動 / 脊髄 / リハビリテーション / cell cycle / HEY / バイオテクノロジー / トランスレーショナルリサーチ / ウイルス / PACAP Less

Functional analysis of CDC5L as a candidate causal gene for ossification of the posterior lingitudinal ligamant of the spine
- Principal Investigator
  
  Tominaga Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Analysis of expression and function of urea transporter UT-B in chondrosarcoma
- Principal Investigator
  
  Sasaki Hiromi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Research for molecular taget of undifferentiatedsarcoma treatment
- Principal Investigator
  
  Setoguchi Takao
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
軟骨肉腫診断マーカーと治療標的候補としてのTGF-βとPEG10の機能解析
- Principal Investigator
  
  YOKOUCHI Masahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Development of new treatment for undifferentiated pleomorphic sarcoma
- Principal Investigator
  
  Izumi Toshihiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Functional analysis of STK38L, the OPLL-associated gene, and research of its target genes in endochondral ossification.
- Principal Investigator
  
  Kakoi Hironori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Identification and functional analysis of candidate causal genes of the ossification of posterior longitudinal ligament of the spine
- Principal Investigator
  
  Kawamura Ichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
New approach to improve delivery of anticancer drugs by modulating extracellular matrix in musculoskeletal tumors
- Principal Investigator
  
  NAGANO Satoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Roles of Atoh8 in differentiation of osteoblasts and adipocytes
- Principal Investigator
  
  MAEDA Shingo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Long-term survival of total joint arthroplasty by drug inhibition of autophagyPrincipal Investigator
- Principal Investigator
  
  Komiya Setsuro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Myct1 as a contact point of TGF-beta and c-Myc; analysis of the function
- Principal Investigator
  
  Ishidou Yasuhiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression
- Principal Investigator
  
  Yamamoto Takuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Research for Molecular Target of Osteosarcoma treatment
- Principal Investigator
  
  Setoguchi Takao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Target gene screening of TGF-b signaling and functional analysis for differentiation-inducing therapy of chondrosarcoma
- Principal Investigator
  
  Yokouchi Masahiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Analysis on function of Smpd3 in chondrocyte maturation and hyaluronan synthesis
- Principal Investigator
  
  Kakoi Hironori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Regenerative therapy for
- Principal Investigator
  
  MASAHIKO Abematsu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
The effect of autophagy activator to neural cells under hypoxic condition
- Principal Investigator
  
  TANABE Fumito
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
GLI2-targeted gene therapy for musculoskeletal tumors
- Principal Investigator
  
  NAGANO Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth
- Principal Investigator
  
  KAWABATA Naoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Fundamental researches to presentation a new animal models and the therapy development of the osteoarthritis
- Principal Investigator
  
  IJIRI KOSEI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Role of GOLPH3 and GOLPH3L in the proliferation of human rhabdomyosarcomaPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsuro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Functional analysis of an oncogene SnoN as a target molecule to regulate progression of osteoarthritis.
- Principal Investigator
  
  MAEDA Shingo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Functional analysis of the novel target gene of bone volume-regulating transcription factor Schnurri-3.
- Principal Investigator
  
  ISHIDOU Yasuhiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Anti-tumor effect of doxorubicin with bubble liposome and ultrasound
- Principal Investigator
  
  YOKOUCHI Masahiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Functional analysis of Smoothened in osteosarcoma via signal cross talk
- Principal Investigator
  
  YAMAMOTO Takuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Notch signaling as a therapeutic target in oral squamous cell carcinoma
- Principal Investigator
  
  HIJIOKA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kagoshima University
Effect of exercise on the aging-degeneration in senescence-accelerated mouse's locomotorium
- Principal Investigator
  
  YONE Kazunori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Molecular target therapy for muscloskeletal sarcoma-initiating cells
- Principal Investigator
  
  SETOGUCHI Takao
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Novel Strategy of Gene Therapy for Musculoskeletal Sarcoma-Targeting Intratumoral Spread of Viral Vectors
- Principal Investigator
  
  NAGANO Satoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Functional analysis of polycomb proteins and target molecules in rheumatoid arthritis pathogenesisPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsuro, 有島善也
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Development of innovative gene therapy of conditionally regulating adenovirus for treating pediatric solid cancer
- Principal Investigator
  
  KOSAI Kenichirou
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation
- Principal Investigator
  
  SETOGUCHI Takao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Targeting of osteosarcoma and soft tissue sarcoma initiating cellsPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsurou
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Pathological mechanism of osteoarthritis -analysis of molecules responsing to mechanical stress-
- Principal Investigator
  
  IJIRI Kosei
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
A New Function of The Lubricin and It's Role in the Pathogenesis of Arthritis.
- Principal Investigator
  
  YAMAMOTO Takuya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Manifestation of HMGB-1 and Preventive Effect of Degeneration on Spinal Cord Following Acute Traumatic Injury.
- Principal Investigator
  
  ARISHIMA Yoshiya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
The inhibitory effects of ubiuitin system in signal transduction of osteosarcoma
- Principal Investigator
  
  HAYASHI Kyouji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
The role of ubiquitination in signal transduction of Osteosarcoma
- Principal Investigator
  
  YOKOUCHI Masahiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
脊髄損傷におけるPACAPの脊髄細胞保護効果とその作用機序に関する研究
- Principal Investigator
  
  吉野伸司
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Preventive effect of erythropoietin on spinal cord degeneration following acute traumatic injury
- Principal Investigator
  
  YONE Kazunori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Gene expression profile during osteoblaslic differentiation of human mesenchymal cells
- Principal Investigator
  
  INOUE Ituro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Ubiquitin system of Src-Cbl negatively regulating the signal transduction of osteoclasts in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsuro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
APOPTOSIS OF CELLS OF NUCLEUS PULPOSUS AND ACTIVATION MECHANISM OF INTERCELLULAR SIGNALING DURING DEGENERATION OF INTERVERTEBRAL DISC
- Principal Investigator
  
  MATSUNAGA Shunji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Biological study for osteoporosis -Apoptosis related gene expression-
- Principal Investigator
  
  IJIRI Kosei
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Genetic mapping of ossification of the posterior longitudinal ligament of the spine
- Principal Investigator
  
  YONE Kazunori, 古賀公明
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Gene therapy for skeletal tumors using a newly developed chimera vectorPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsuro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Therapeatic study for osteosarcoma controling signal transduction
- Principal Investigator
  
  ZENMYO Michihisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Relationship of p21 (wafl/cip1) and differentiation in chondrosarcoma
- Principal Investigator
  
  HIRAOKA Koji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Expression of CD44 in OSA cell lines
- Principal Investigator
  
  NARITA Syugo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Therapeutic induction of apoptosis into musculoskeletal tumorsPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsuro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Role of hyaluronic acid on bone destruction and pulmonary metastasis in tumorsPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsuro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Metastatic mechanism of bone and soft tissue tumors from the view point of matrix-metalloproteinasesPrincipal Investigator
- Principal Investigator
  
  KOMIYA Setsurou
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University

[Book] 骨軟部肉腫におけるゴルジ装置タンパクGOLPH3とGOLPH3Lの発現上昇と細胞増殖への関与2012
- Author(s)
  瀬戸口啓夫、救仁郷修、中村俊介、永野聡、横内雅博、小宮節郎
- Publisher
  生体の科学
- Data Source
  KAKENHI-PROJECT-23592195
[Book] バイオプシーの進め方、整形外科基本手技2011
- Author(s)
  永野聡、小宮節郎
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-21591920
[Book] 関節外科2007
- Author(s)
  瀬戸口啓夫小宮節郎近藤亨
- Publisher
  がん幹細胞と治療抵抗性
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] PEG10 counteracts signaling pathways of TGF-β and BMP to regulate growth, motility and invasion of SW1353 chondrosarcoma cells2018
- Author(s)
  Yahiro Yuhei、Maeda Shingo、Shinohara Naohiro、Jokoji Go、Sakuma Daisuke、Setoguchi Takao、Ishidou Yasuhiro、Nagano Satoshi、Komiya Setsuro、Taniguchi Noboru
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: ahead of print Issue: 3 Pages: 441-454
- DOI
  10.1007/s00774-018-0946-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10972, KAKENHI-PROJECT-18K09036
[Journal Article] Clinical course of the bony lesion of single-system single-site Langerhans cell histiocytosis - Is appropriate follow-up sufficient treatment?2018
- Author(s)
  Sasaki H, Nagano S, Shimada H, Nakamura S, Setoguchi T, Komiya S.
- Journal Title
  
  J Orthop Sci.
  
  Volume: 23 Issue: 1 Pages: 168-173
- DOI
  10.1016/j.jos.2017.08.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10452
[Journal Article] Prognostic factors in patients with skeletal-related events at non-small-cell lung cancer diagnosis.2017
- Author(s)
  Tominaga H, Setoguchi T, Shimada H, Nagano S, Sasaki H, Ishidou Y, Sato M, Mizuno K, Inoue H, Komiya S.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 7 Issue: 5 Pages: 897-902
- DOI
  10.3892/mco.2017.1394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10452
[Journal Article] Diagnosing and discriminating between primary and secondary aneurysmal bone cysts.2017
- Author(s)
  Sasaki H, Nagano S, Shimada H, Yokouchi M, Setoguchi T, Ishidou Y, Kunigou O, Maehara K, Komiya S.
- Journal Title
  
  Oncol Lett.
  
  Volume: 13 Issue: 4 Pages: 2290-2296
- DOI
  10.3892/ol.2017.5682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10452
[Journal Article] TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells.2017
- Author(s)
  Shinohara N, Maeda S, Yahiro Y, Sakuma D, Matsuyama K, Imamura K, Kawamura I, Setoguchi T, Ishidou Y, Nagano S, Komiya S.
- Journal Title
  
  Sci Rep.
  
  Volume: 18 Issue: 1 Pages: 13494-13494
- DOI
  10.1038/s41598-017-13994-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10452
[Journal Article] Inhibition of casein kinase 2 prevents growth of human osteosarcoma.2017
- Author(s)
  Takahashi K, Setoguchi T, Tsuru A, Saitoh Y, Nagano S, Ishidou Y, Maeda S, Furukawa T, Komiya S.
- Journal Title
  
  Oncol Rep.
  
  Volume: 37 Issue: 2 Pages: 1141-1147
- DOI
  10.3892/or.2016.5310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10452, KAKENHI-PROJECT-16K07121
[Journal Article] Targeting Epigenetics in Treatment of Cancer and Sarcoma2017
- Author(s)
  Saito Y, Setoguchi T, Komiya S.
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 44（３） Pages: 217-221
- Data Source
  KAKENHI-PROJECT-17K10973
[Journal Article] Combination of Hedgehog inhibitors and standard anticancer agents synergistically prevent osteosarcoma growth.2016
- Author(s)
  Saitoh Y, Setoguchi T, Nagata M, Tsuru A, Nakamura S, Nagano S, Ishidou Y, Nagao-Kitamoto H, Yokouchi M, Maeda S, Tanimoto A, Furukawa T, Komiya S.
- Journal Title
  
  Int J Oncol.
  
  Volume: 48 Issue: 1 Pages: 235-42
- DOI
  10.3892/ijo.2015.3236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10452, KAKENHI-PROJECT-25462342
[Journal Article] Cut-off values of latent infection in patients with rapid migration following bipolar hip hemiarthroplasty.2016
- Author(s)
  Setoguchi T, Kawakami H, Ishidou Y, Kawamura H, Nishi J, Yoshioka T, Kakoi H, Nagano S, Yokouchi M, Tanimoto A, Komiya S.
- Journal Title
  
  BMC Musculoskelet Disord.
  
  Volume: 17 Issue: 1 Pages: 37-37
- DOI
  10.1186/s12891-016-0876-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462306, KAKENHI-PROJECT-25870567, KAKENHI-PROJECT-16H05845
[Journal Article] Differentiation of lipoma and atypical lipomatous tumor by a scoring system: implication of increased vascularity on pathogenesis of liposarcoma.2015
- Author(s)
  Nagano S, Yokouchi M, Setoguchi T, Ishidou Y, Sasaki H, Shimada H, Komiya S.
- Journal Title
  
  BMC Musculoskelet Disord.
  
  Volume: 16 Issue: 1 Pages: 36-36
- DOI
  10.1186/s12891-015-0491-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592237
[Journal Article] Enrichment of bacteria samples by centrifugation improves the diagnosis of orthopaedics-related infections via real-time PCR amplification of the bacterial methicillin-resistance gene.2015
- Author(s)
  Tsuru A, Setoguchi T, Kawabata N, Hirotsu M, Yamamoto T, Nagano S, Yokouchi M, Kakoi H, Kawamura H, Ishidou Y, Tanimoto A, Komiya S.
- Journal Title
  
  BMC Res Notes.
  
  Volume: 8 Issue: 1 Pages: 288-288
- DOI
  10.1186/s13104-015-1180-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462306, KAKENHI-PROJECT-25870567
[Journal Article] Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression.2015
- Author(s)
  Tsuru A, Setoguchi T, Matsunoshita Y, Nagao-Kitamoto H, Nagano S, Yokouchi M, Maeda S, Ishidou Y, Yamamoto T, Komiya S.
- Journal Title
  
  Br J Cancer.
  
  Volume: 112 Issue: 7 Pages: 1232-40
- DOI
  10.1038/bjc.2015.84
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-25462341, KAKENHI-PROJECT-25462342
[Journal Article] GLI2 is a novel therapeutic target for metastasis of osteosarcoma.2015
- Author(s)
  Nagao-Kitamoto H, Nagata M, Nagano S, Kitamoto S, Ishidou Y, Yamamoto T, Nakamura S, Tsuru A, Abematsu M, Fujimoto Y, Yokouchi M, Kitajima S, Yoshioka T, Maeda S, Yonezawa S, Komiya S, Setoguchi T.
- Journal Title
  
  Int J Cancer.
  
  Volume: 136 Issue: 6 Pages: 1276-1284
- DOI
  10.1002/ijc.29107
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-24592238, KAKENHI-PROJECT-25462342
[Journal Article] Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion.2015
- Author(s)
  Nagao-Kitamoto H, Setoguchi T, Kitamoto S, Nakamura S, Tsuru A, Nagata M, Nagano S, Ishidou Y, Yokouchi M, Kitajima S, Yoshioka T, Maeda S, Yonezawa S, Komiya S.
- Journal Title
  
  Cancer Lett.
  
  Volume: 356 Issue: 2 Pages: 855-861
- DOI
  10.1016/j.canlet.2014.10.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-25462342
[Journal Article] Metastatic bone tumors: Analysis of factors affecting prognosis and efficacy of CT and 18F-FDG PET-CT in identifying primary lesions.2014
- Author(s)
  Shimada H, Setoguchi T, Yokouchi M, Sasaki H, Ishidou Y, Kawamura I, Abematsu M, Nagano S, Komiya S.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 2(5) Issue: 5 Pages: 875-881
- DOI
  10.3892/mco.2014.326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592203
[Journal Article] Human Immunodeficiency Virus Type I Enhancer Binding Protein 3 is Essential for the Expression of Asparagine-linked Glycosylation 2 in the Regulation of Osteoblast and Chondrocyte Differentiation.2014
- Author(s)
  Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Issue: 14 Pages: 9865-9879
- DOI
  10.1074/jbc.m113.520585
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592221, KAKENHI-PROJECT-23592222, KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-25462376
[Journal Article] BMP signaling upregulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt signaling pathway as a negative feedback mechanism.2014
- Author(s)
  Kakoi H, Maeda S, Shinohara N, Matsuyama K, Imamura K, Kawamura I, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Issue: 12 Pages: 8135-8150
- DOI
  10.1074/jbc.m113.509331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592221, KAKENHI-PROJECT-23592222, KAKENHI-PROJECT-25462376
[Journal Article] Human Immunodeficiency Virus Type I Enhancer Binding Protein 3 is Essential for the Expression of Asparagine-linked Glycosylation 2 in the Regulation of Osteoblast and Chondrocyte Differentiation2014
- Author(s)
  Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 9865-9879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592222
[Journal Article] Metastatic bone tumors: Analysis of factors affecting prognosis and efficacy of CT and 18F-FDG PET-CT in identifying primary lesions.2014
- Author(s)
  Shimada H, Setoguchi T, Yokouchi M, Sasaki H, Ishidou Y, Kawamura I, Abematsu M, Nagano S, Komiya S.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 2 Pages: 875-881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592237
[Journal Article] Elastofibroma dorsi: Surgical indications and complications of a rare soft tissue tumor.2014
- Author(s)
  Nagano S, Yokouchi M, Setoyama T, Sasaki H, Shimada H, Kawamura I, Ishidou Y, Setoguchi T, Komiya S
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 2 Issue: 3 Pages: 421-424
- DOI
  10.3892/mco.2014.257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592237
[Journal Article] BMP signaling upregulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt signaling pathway as a negative feedback mechanism2014
- Author(s)
  Kakoi H, Maeda S, Shinohara N, Matsuyama K, Imamura K, Kawamura I, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 8135-8150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592222
[Journal Article] Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny2014
- Author(s)
  Tanoue K, Wang Y, Ikeda M , Mitsui K, Irie R , Setoguchi T, Komiya S, Natsugoe S, Kosai K
- Journal Title
  
  J Trans Med
  
  Volume: 12 Issue: 1 Pages: 27-27
- DOI
  10.1186/1479-5876-12-27
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23659159, KAKENHI-PROJECT-23701062, KAKENHI-PROJECT-24591099, KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-24592238, KAKENHI-PROJECT-24791076, KAKENHI-PROJECT-25293234, KAKENHI-PROJECT-25462342, KAKENHI-PROJECT-25670194
[Journal Article] Human Immunodeficiency Virus Type I Enhancer Binding Protein 3 is Essential for the Expression of Asparagine-linked Glycosylation 2 in the Regulation of Osteoblast and Chondrocyte Differentiation2014
- Author(s)
  Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 9865-9879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592221
[Journal Article] Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.2013
- Author(s)
  Nakamura S, Nagano S, Nagao H, Ishidou Y, Yokouchi M, Abematsu M, Yamamoto T, Komiya S, Setoguchi T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 7 Pages: e69466-e69466
- DOI
  10.1371/journal.pone.0069466
- NAID
  120005324788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-24592238, KAKENHI-PROJECT-25462342
[Journal Article] SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways2012
- Author(s)
  Kawamura I, Maeda S, Imamura K, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 29101-29113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592222
[Journal Article] Treatment of a mouse model of spinal cord injury by transplantation of human iPS cell-derived long-term self-renewing neuroepithelial-like stem cells2012
- Author(s)
  Fujimoto Y., Abematsu M., FalkA., Tsujimura K., Sanosaka T., Juliandi B.. Semi K., Namihira M., Komiya S., SmithA., Nakashima K,
- Journal Title
  
  Stem Cells
  
  Volume: 30 Issue: 6 Pages: 1163-1173
- DOI
  10.1002/stem.1083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09295, KAKENHI-PUBLICLY-23123514, KAKENHI-PUBLICLY-23123515, KAKENHI-PROJECT-23650215, KAKENHI-PROJECT-24592203, KAKENHI-PROJECT-24880023
[Journal Article] RBPJ Is a Novel Target for Rhabdomyosarcoma Therapy.2012
- Author(s)
  Hiroko Nagao, Takao Setoguchi, Sho Kitamoto, Yasuhiro Ishidou, Satoshi Nagano, Masahiro Yokouchi, Masahiko Abematsu, Naoya Kawabata, Shingo Maeda, Suguru Yonezawa, Setsuro Komiya
- Journal Title
  
  PLoS ONE
  
  Volume: 7(7) Issue: 7 Pages: e39268-e39268
- DOI
  10.1371/journal.pone.0039268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-22591662, KAKENHI-PROJECT-24592237, KAKENHI-PROJECT-24592238
[Journal Article] 分子レベルからみた整形外科疾患(シリーズ IX) Bubble liposome と超音波を併用した drug delivery system の開発2012
- Author(s)
  上野宜功, 園田祥三, 丸山一雄, 坂本泰二, 横内雅博, 小宮節郎
- Journal Title
  
  整形・災害外科
  
  Volume: 55巻 12号 Pages: 1488-1489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report.2012
- Author(s)
  Tanaka M, Setoguchi T, Ishidou Y, Arishima Y, Hirotsu M, Saitoh Y, Nakamura S, Kakoi H, Nagano S, Yokouchi M, Kamizono J, Komiya S.
- Journal Title
  
  Diagn Pathol
  
  Volume: 7 Issue: 1
- DOI
  10.1186/1746-1596-7-108
- NAID
  120005342565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592237
[Journal Article] SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways2012
- Author(s)
  Kawamura I, Maeda S, Imamura K, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S
- Journal Title
  
  J Biol Chem
  
  Volume: 287(34) Issue: 34 Pages: 29101-13
- DOI
  10.1074/jbc.m112.349415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662, KAKENHI-PROJECT-23592221, KAKENHI-PROJECT-23592222
[Journal Article] Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth2011
- Author(s)
  Kawabata N, Ijiri K, Ishidou Y, Yamamoto T, Nagao H, Nagano S, Maeda S, Komiya S, Setoguchi T.
- Journal Title
  
  Int J Oncol
  
  Volume: 399 Pages: 899-906
- DOI
  10.3892/ijo.2011.1076
- NAID
  120005342568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919, KAKENHI-PROJECT-21591920, KAKENHI-PROJECT-22591663, KAKENHI-PROJECT-23592195
[Journal Article] Role of GOLPH3 and GOLPH3L in the proliferation of human rhabdomyosarcoma2011
- Author(s)
  Kunigou O., Nagao H., Kawabata N., Ishidou Y., Nagano S., Maeda S., Komiya S., and Setoguchi T.
- Journal Title
  
  Oncology Reports
  
  Volume: 5 Pages: 1337-42
- DOI
  10.3892/or.2011.1413
- NAID
  120005342567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919, KAKENHI-PROJECT-21591920, KAKENHI-PROJECT-22591663, KAKENHI-PROJECT-23592195
[Journal Article] Role of GOLPH3 and GOLPH3L in the proliferation of human rhabdomyosarcoma2011
- Author(s)
  Kunigou O., Nagao H., Kawabata N., Ishidou Y., Nagano S., Maeda S., Komiya S., and Setoguchi T
- Journal Title
  
  Corresponding author Oncology Reports
  
  Volume: 5 Pages: 1337-42
- NAID
  120005342567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592195
[Journal Article] Clinical implications of determination of safe surgical margins by using a combination of CT and 18FDG-positron emission tomography in soft tissue sarcoma2011
- Author(s)
  Yokouchi M, Terahara M, Nagano S, Arishima Y, Zemmyo M, Yoshioka T, Tanimoto A, Komiya S.
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 12 Pages: 166-166
- URL
  http://www.biomedcentral.com/1471-2474/12/166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591920
[Journal Article] Clinical implications of determination of safe surgical margins by using a combination of CT and 18FDG-positron emission tomography in soft tissue sarcoma.2011
- Author(s)
  Yokouchi M, Terahara M, Nagano S, Arishima Y, Zemmyo M, Yoshioka T, Tanimoto A, Komiya S.
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 12 Issue: 1 Pages: 166-166
- DOI
  10.1186/1471-2474-12-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Combination of ultrasound and bubble liposome enhance the effect of doxorubicin and inhibit murine osteosarcoma growth2011
- Author(s)
  Ueno Y, Sonoda S, Suzuki R, Yokouchi M, Kawasoe Y, Tachibana K, Maruyama K, Sakamoto T, Komiya S
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 12(4) Pages: 270-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Clinical implications of determination of safe surgical margins by using a combination of CT and 18FDG-positron emission tomography in soft tissue sarcoma2011
- Author(s)
  Yokouchi M, Terahara M, Nagano S, Arishima Y, Zemmyo M, Yoshioka T, Tanimoto A, Komiya S
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 12 Pages: 166-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Suppression of osteosarcoma cell inva sion by chemotherapy is mediated by ur okinase plasminogen activator activity vi a up-regulation of EGR1.2011
- Author(s)
  Matsunoshita Y, Ijiri K, Ishidou Y, Nagano S, Yamamoto T, Nagao H, Komiya S, Setoguchi T.
- Journal Title
  
  PLoS One. 6(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR12011
- Author(s)
  Matsunoshita Y, Ijiri K, Ishidou Y, Nagano S, Yamamoto T, Nagao H, Komiya S, Setoguchi T.
- Journal Title
  
  PLoS One
  
  Volume: 6(1)
- NAID
  120005342569
- URL
  http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591920
[Journal Article] Suppression of Osteosarcoma Cell Invasion by Chemotherapy Is Mediated by Urokinase Plasminogen Activator Activity via Up-Regulation of EGR12011
- Author(s)
  Matsunoshita Y, Ijiri K, Ishidou Y, Nagano S, Yamamoto T, Nagao H, Komiya S, Setoguchi T.
- Journal Title
  
  Corresponding author PLoS ONE
  
  Volume: 6(1) Issue: 1 Pages: e16234-e16234
- DOI
  10.1371/journal.pone.0016234
- NAID
  120005342569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591663
[Journal Article] Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses : implications for the generation of ideal m-CRAs2011
- Author(s)
  Horikawa Y, Wang Y, Nagano S, Kamizono J, Ikeda M, Komiya S, Kosai KI.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 18(10) Issue: 10 Pages: 724-33
- DOI
  10.1038/cgt.2011.44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591920, KAKENHI-PROJECT-22390210
[Journal Article] Role of GLI2 in the growth of human osteosarcoma2011
- Author(s)
  Nagao H., Ijiri K., Hirotsu M., Ishidou Y., Yamamoto T., Nagano S., Takizawa T., Nakashima K., Komiya S., and Setoguchi T.
- Journal Title
  
  The Journal of Pathology
  
  Volume: 224 Issue: 2 Pages: 169-79
- DOI
  10.1002/path.2880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919, KAKENHI-PROJECT-21591920, KAKENHI-PROJECT-22591663, KAKENHI-PROJECT-23592195
[Journal Article] Role of GLI2 in the growth of human osteosarcoma2011
- Author(s)
  Nagao H., Ijiri K., Hirotsu M., Ishidou Y., Yamamoto T., Nagano S., Takizawa T., Nakashima K., Komiya S., and Setoguchi T
- Journal Title
  
  Corresponding author The Journal of Pathology
  
  Volume: 224 Pages: 169-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591663
[Journal Article] Suppression of Osteosarcoma Cell Invasion by Chemotherapy Is Mediated by Urokinase Plasminogen Activator Activity via Up-Regulation of EGR12011
- Author(s)
  Matsunoshita Y, Ijiri K, Ishidou Y, Nagano S, Yamamoto T, Nagao H, Komiya S, Setoguchi T.
- Journal Title
  
  PLoS ONE
  
  Volume: 6(1)
- NAID
  120005342569
- URL
  http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919
[Journal Article] Combination of ultrasound and bubble liposome enhance the effect of doxorubicin and inhibit murine osteosarcoma growth2011
- Author(s)
  Ueno Y, Sonoda S, Suzuki R, Yokouchi M, Kawasoe Y, Tachibana K, Maruyama K, Sakamoto T, Komiya S.
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 12(4) Pages: 270-7
- URL
  http://www.landesbioscience.com/journals/cbt/article/16259/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591920
[Journal Article] High mobility group box 1 is upregulated after spinal cord injury and is associated with neuronal cell apoptosis.2010
- Author(s)
  Kawabata H, Setoguchi T, Yone K, Souda M, Yoshida H, Kawahara K, Maruyama I, Komiya S.
- Journal Title
  
  Spine 35(11)
  
  Pages: 1109-15
- NAID
  10027252218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Smoothened as a new therapeutic target for human osteosarcoma2010
- Author(s)
  Hirotsu M. §, Setoguchi T. §†, Sasaki H. §, Matsunoshita Y., Gao H., Nagao H., Kunigou O., Komiya S
- Journal Title
  
  These three authors contributed equally. † Corresponding author Molecular Cancer
  
  Volume: (9) Issue: 1 Pages: 5-5
- DOI
  10.1186/1476-4598-9-5
- NAID
  120005342572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591663
[Journal Article] Knock down of over-expressed EZH2 and BMI-1 do not prevent osteosar coma growth2010
- Author(s)
  Setoguchi T., Komiya S., 他4名
- Journal Title
  
  Oncology Reports 23
  
  Pages: 677-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Mazabraud's syndrome with solitary myxoma and monostotic fibrous dysplasia.2010
- Author(s)
  Arishima Y, Setoguchi T, Abematsu M, Tominaga H, Fukunaga E, Komiya S.
- Journal Title
  
  J Orthop Sci. 15(1)
  
  Pages: 144-147
- NAID
  10027403265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] The knock-down of overexpressed EZ H2 and BMI-1 does not prevent osteosa rcoma growth.2010
- Author(s)
  Sasaki H, Setoguchi T, Matsunoshita Y, Gao H, Hirotsu M, Komiya S.
- Journal Title
  
  Oncol Rep. 23(3)
  
  Pages: 677-684
- NAID
  120005342571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Upregulation of Notch pathway molecules in oral squamous cell carcinoma2010
- Author(s)
  Hijioka H, Setoguchi T, Miyawaki A, Gao H, Ishida T, Komiya S, and Nakamura N.
- Journal Title
  
  Int J Oncol
  
  Volume: 36 Pages: 817-822
- NAID
  120005342570
- URL
  http://www.spandidos-publications.com/ijo/36/4/817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919
[Journal Article] Smoothened as a new therapeutic tar get for human osteosarcoma.2010
- Author(s)
  Hirotsu M, Setoguchi T, Sasaki H, Matsunoshita Y, Gao H, Nagao H, Kunigou O, Komiya S.
- Journal Title
  
  Mol Cancer 9
  
  Pages: 5-5
- NAID
  120005342572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Smoothened as a new therapeutic target for human osteosarcoma2010
- Author(s)
  Hirotsu M., Setoguchi T., Sasaki H.§, Matsunoshita Y., Gao H., Nagao H., Kunigou O., Komiya S.
- Journal Title
  
  Molecular Cancer
  
  Volume: 9 Pages: 5-5
- NAID
  120005342572
- URL
  http://www.molecular-cancer.com/content/9/1/5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919
[Journal Article] Upregulation of Notch pathway molec ules in oral squamous cell carcinoma.2010
- Author(s)
  Hijioka H, Setoguchi T, Miyawaki A, Gao H, Ishida T, Komiya S, Nakamura N.
- Journal Title
  
  Int J Oncol. 36(4)
  
  Pages: 817-822
- NAID
  120005342570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Smoothened as a new therapeutic target for human osteosarcoma2010
- Author(s)
  Hirotsu M., Setoguchi T., Sasaki H. Matsunoshita Y., Gao H., Nagao H., Kunigou O., Komiya S
- Journal Title
  
  Molecular Cancer
  
  Volume: 9 Pages: 5-5
- NAID
  120005342572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592241
[Journal Article] Gadd45β expression in chondrosarcoma: a pilot study for diagnostic and biological implications in histological grading2010
- Author(s)
  Zenmyo M, Tanimoto A, Sakakima H, Yokouchi M, Nagano S, Yamamoto T, Ishido Y, Komiya S, Ijiri K
- Journal Title
  
  Diagn Pathol
  
  Volume: 5 Issue: 1 Pages: 69-69
- DOI
  10.1186/1746-1596-5-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591662
[Journal Article] Knock down of over-expressed EZH2 and BMI-1 do not prevent osteosarcoma growth2010
- Author(s)
  Sasaki H., Setoguchi T., Matsunoshita Y., Gao H., Hirotsu M., Komiya S.
- Journal Title
  
  Oncology Reports
  
  Volume: 23 Pages: 677-84
- URL
  http://www.spandidos-publications.com/or/23/3/677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919
[Journal Article] Upregulation of Notch pathway molecules in oral squamous cell carcinoma2010
- Author(s)
  Hijioka H, Setoguchi T, Miyawaki A, Gao H, Ishida T, Komiya S, and Nakamura N
- Journal Title
  
  Int J Oncol
  
  Volume: 36 Issue: 4 Pages: 817-822
- DOI
  10.3892/ijo_00000558
- NAID
  120005342570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592241
[Journal Article] Retinal astrocyte differentiation mediated by leukemia inhibitory factor in cooperation with bone morphogenetic protein 22009
- Author(s)
  Setoguchi T., Komiya S., 他3名
- Journal Title
  
  International Journal of Developmental Neuroscience 27
  
  Pages: 685-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Stem cell factor prevents neuronal cell apoptosis after acute spinal cord injury2009
- Author(s)
  Setoguchi T., Komiya S., 他3名
- Journal Title
  
  Spine 34
  
  Pages: 323-7
- NAID
  10027238493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
- Journal Title
  
  Arthritis Rheum. 60(1)
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells2009
- Author(s)
  Hirotsu M, Setoguchi T, MatsunoshitaY, Sasaki H, Nagao H, Gao H, Sugimura K, Komiya S.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 101 Pages: 2030-37
- URL
  http://www.nature.com/bjc/journal/v101/n12/full/6605407a.html
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591919
[Journal Article] Expression of osterix inhibits bone morphogenetic protein-induced chondrogenic differentiation of mesenchymal progenitor cells2009
- Author(s)
  Tominaga H, Maeda S, Miyoshi H, Miyazono K, Komiya S, Imamura T
- Journal Title
  
  J Bone Miner Metab. 27(1)
  
  Pages: 36-45
- NAID
  10025336129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis2009
- Author(s)
  Taniguchi N, Carames B, Ronfani L, Ulmer U, Komiya S, Bianchi ME, Lotz M
- Journal Title
  
  Proc Natl Acad Sci USA 106(4)
  
  Pages: 1181-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Stress deprivation from the patellar tendon induces apoptosis of fibroblasts in vivo with activation of mitogen-activated protein kinases.2009
- Author(s)
  Kawabata H, Katsura T, Kondo E, Kitamura N, Miyatake S, Tanabe Y, Setoguchi T, Komiya S, Yasuda K.
- Journal Title
  
  J Biomech. 42(15)
  
  Pages: 2611-2615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Retinal astrocyte differentiation mediated by leukemia inhibitory factor in cooperation with bone morphogenetic prote in 2.2009
- Author(s)
  Fukushima M, Setoguchi T, Komiya S, Tanihara H, Taga T.
- Journal Title
  
  Int J Dev Neurosci. 27(7)
  
  Pages: 685-690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation2009
- Author(s)
  Motoyuki Tanaka, Takao Setoguchi, Masataka Hirotsu, Hui Gao, Hiromi Sasaki, Yukihiro Matsunoshita, Setsuro Komiya
- Journal Title
  
  British Journal of Cancer 100
  
  Pages: 1957-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation2009
- Author(s)
  Motoyuki Tanaka^1, Takao Setoguchi1, Masataka Hirotsu, Hui Gao, Hiromi Sasaki, Yukihiro Matsunoshita, Setsuro Komiya
- Journal Title
  
  ^1These two authors contributed equally 100
  
  Pages: 1957-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Stem cell factor prevents neuronal cell apoptosis after acute spinal cord injury.2009
- Author(s)
  Yamasaki K, Setoguchi T, Takenouchi T, Yone K, Komiya S
- Journal Title
  
  Spine. 15;34(4)
  
  Pages: 323-7
- NAID
  10027238493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells.2009
- Author(s)
  Hirotsu M, Setoguchi T, Matsunoshita Y, Sasaki H, Nagao H, Gao H, Sugimura K, Komiya S.
- Journal Title
  
  Br J Cancer 101(12)
  
  Pages: 2030-2037
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis.2009
- Author(s)
  Taniguchi N, Carames B, Ronfani L, Ulmer U, Komiya S, Bianchi ME, Lotz M
- Journal Title
  
  Proc Natl Acad Sci USA 27;(106)4
  
  Pages: 1181-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha.2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruayama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
- Journal Title
  
  Arthritis Rheum 60(1)
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Stem cell factor prevents neuronal cell apoptosis after acute spinal cord injury.2009
- Author(s)
  Yamasaki K, Setoguchi T, Takenouchi T, Yone K, Komiya S.
- Journal Title
  
  Spine 34(4)
  
  Pages: 323-327
- NAID
  10027238493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Stem cell factor prevents neuronal cell apoptosis after acute spinal cord injury2009
- Author(s)
  Yamasaki K, Setoguchi T, Takenouchi T, Yone K, Komiya S
- Journal Title
  
  Spine 34(4)
  
  Pages: 323-7
- NAID
  10027238493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells2009
- Author(s)
  Fukunaga E, Inoue Y, Komiya S, Horiguchi K, Goto K, Saitoh M, Miyazawa K, Koinuma D, Hanyu A, Imamura T
- Journal Title
  
  J Biol Chem. 283(51)
  
  Pages: 35660-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation.2009
- Author(s)
  Tanaka M, Setoguchi T, Hirotsu M, Gao H, Sasaki H, Matsunoshita Y, Komiya S.
- Journal Title
  
  Br J Cancer 100(12)
  
  Pages: 1957-1965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] CAAT/enhancer-binding protein beta promotes osteoblast differentiation by enhancing Runx2 activity with ATF4.2008
- Author(s)
  Tominaga H, Maeda S, Hayashi M, Takeda S, Akira S, Komiya S, Nakamura T, Akiyama H, Imamura T
- Journal Title
  
  Mol Biol Cell. 19(12)
  
  Pages: 5373-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] 増殖制御型アデノウイルスによる遺伝子治療.2008
- Author(s)
  堀川良治, 小宮節郎, 小戝健一郎
- Journal Title
  
  関節外科基礎と臨床。 27(1)
  
  Pages: 132-133
- Data Source
  KAKENHI-PROJECT-19390286
[Journal Article] Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.2008
- Author(s)
  Uhuru Jm Zerbini LF, Peng H, Otu HH, Tsuchimochi K, Otero M, Dragomir C, Walsh N, Bierbaum BE, Mattingly D, van Flandern G, Komiya S, Aigner T, Libermann TA, Goldring MB
- Journal Title
  
  Arthritis Rheum. 58(7)
  
  Pages: 2075-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis.2008
- Author(s)
  Hamada T, Torikai M, Kuwazuru A, Tanaka M, Horai N, Fukuda T, Yamada S, Nagayama S, Hashiguchi K, Sunahara N, Fukuzaki K, Nagata R, Komiya S, Maruyama I, Fukuda T, Abeyama K
- Journal Title
  
  Arthritis Rheum. 58(9)
  
  Pages: 2675-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Expression of apoptosis signal-regulating kinase 1 in mouse spinal cord under chronic mechanical compression : possible involvement of the stress-activated mitogen-activated protein kinase pathways in spinal cord cell apoptosis2008
- Author(s)
  Takenouchi T, Setoguchi T, Yone K, Komiya S
- Journal Title
  
  Spine 33(18)
  
  Pages: 1943-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Expression of apoptosis signal-regulating kinase 1 in mouse spinal cord under chronic mechanical compression: possible involvement of the stress-activated mitogen-activated protein kinase pathways in spinal cord cell apoptosis.2008
- Author(s)
  Takenouchi T, Setoguchi T, Yone K, Komiya S.
- Journal Title
  
  Soine 15;33(18)
  
  Pages: 1943-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis2008
- Author(s)
  Hamada T, Torikai M, Kuwazuru A, Tanaka M, Horai N, Fukuda T, Yamada S, Nagayama S, Hashiguchi K, Sunahara N, Fukuzaki K, Nagata R, Komiya S, Maruyama I, Fukuda T, Abeyama K
- Journal Title
  
  Arthritis Rheum. 58(9)
  
  Pages: 2675-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] CCAAT/enhancer-binding protein beta promotes osteoblast differentiation by enhancing Runx2 activity with ATF4.2008
- Author(s)
  Tominaga H, Maeda S, Hayashi M, Takeda S, Akira S, Komiya S, Nakamura T, Akiyama H, Imamura T
- Journal Title
  
  Mol Biol Cell. 19(12)
  
  Pages: 5373-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Expression of apoptosis signal-regulating kinase 1 in mouse spinal cord under chronic mechanical compression : possible involvement of the stress-activated mitogen-activated protein kinase pathways in spinal cord cell apoptosis.2008
- Author(s)
  Takenouchi T, Setoguchi T, Yone K, Komiya S.
- Journal Title
  
  Spine 33(18)
  
  Pages: 1943-1950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591786
[Journal Article] Differential Expression of GADD45β in Normal and Osteoarthritic Cartilage Potential Role in Homeostasis of Articular Chondrocytes2008
- Author(s)
  Ijiri, K., Zerbini, L., Peng, H., Out, HH., Tsuchimochi, K., Otero, M., Dragomir, C., Walsh, N., Bierbaum, BE., Mattingly, D., Flandern, G., Komiya, S., Aigner, T., Libermann, TA., Goldring, MB
- Journal Title
  
  Arthritis Rheum 58
  
  Pages: 2075-2087
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591636
[Journal Article] Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.2008
- Author(s)
  Fukunaga E, Inoue Y, Komiya S, Horiguchi K, Goto K, Saitoh M, Miyazawa K, Koinuma D, Hanyu A, Imamura T
- Journal Title
  
  J Biol Chem. 19;283(51)
  
  Pages: 35660-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Differential expression of GADD45beta in normal and osteoarthritic cartilage : potential role in homeostasis of articular chondrocytes2008
- Author(s)
  Ijiri K, Zerbini LF, Peng H, Out HH, Tsuchimochi K, Otero M, Dragomir C, Walsh N, Bierbaum BE, Mattingly D, van Flandern G, Komiya S, Aigner T, Libermann TA, Goldring MB
- Journal Title
  
  Arthritis Rheum. 58(7)
  
  Pages: 2075-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Expression of osterix inhibits bone morphogenetic protein-induced chondrogenic differentiation of mesenchymal progenitor cells.2008
- Author(s)
  Tominaga H, Maeda S, Miyoshi H, Miyazono K, Komiya S, Imamura T
- Journal Title
  
  J Bone Miner Metab. 27(1)
  
  Pages: 36-45
- NAID
  10025336129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification2007
- Author(s)
  Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H
- Journal Title
  
  Mol Cell Biol. 27(16)
  
  Pages: 5650-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification.2007
- Author(s)
  Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H.
- Journal Title
  
  Mol Cell Biol. 27(16)
  
  Pages: 5650-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591725
[Journal Article] Suppression of IL-6 production and proliferation by blocking STAT3 activation in malignant soft tissue tumor cells2006
- Author(s)
  Shouda T, Hiraoka K, Komiya S, Hamada T, Zenmyo M, Iwasaki H, Isayama T, Fukushima N, Nagata K, Yoshimura A
- Journal Title
  
  Cancer Lett 231(2)
  
  Pages: 176-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells2006
- Author(s)
  Tofuku K, Yokouchi M, Murayama T, Minami S, Komiya S
- Journal Title
  
  Int J Oncol. 29(1)
  
  Pages: 175-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells.2006
- Author(s)
  Tofuku K, Yokouchi M, Murayama T, Minami S, Komiya S.
- Journal Title
  
  International journal of oncology 29(1)
  
  Pages: 175-183
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage2006
- Author(s)
  Sato T, Konomi K, Yamasaki S, Aratani S, Tsuchimochi K, Yokouchi M, Masuko-Hongo K, Yagishita N, Nakamura H, Komiya S, Beppu M, Aoki H, Nishioka K, Nakajima T
- Journal Title
  
  Arthritis Rheum. 54(3)
  
  Pages: 808-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390419
[Journal Article] 骨肉腫の浸潤・転移において重要な役割をはたすヒアルロン酸の検討2005
- Author(s)
  東福勝宏, 横内雅博, 村山隆, 南周作, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 79・8号
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫の浸潤・転移において重要な役割をはたすヒアルロン酸の検討2005
- Author(s)
  東福勝宏, 横内雅博, 村山隆, 南周作, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 79巻8号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 骨肉腫細胞株におけるPDGF受容体の発現とそのシグナル抑制機構2004
- Author(s)
  村山隆, 山下芳隆, 南周作, 横内雅博, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78・6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 腫瘍領域における先端医療の成果と展望 Cb1の増殖因子シグナル制御による骨肉腫治療の可能性2004
- Author(s)
  横内雅博, 村山隆, 山下芳隆, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78・8号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫におけるEGFR/Src/Cb1間シグナル伝達機構2004
- Author(s)
  山下芳隆, 横内雅博, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 小児骨肉腫における有効な分子標的治療の検討2004
- Author(s)
  横内雅博, 村山隆, 山下芳隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  小児がん 41巻3号
  
  Pages: 675-675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 小児骨肉腫における有効な分子標的治療の検討2004
- Author(s)
  横内雅博, 山下芳隆, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本小児血液学会雑誌 18巻4号
  
  Pages: 414-414
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 骨肉腫のシグナル伝達におけるSrcの役割2004
- Author(s)
  山下芳隆, 横内雅博, 村山隆, 南周作, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻8号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫細胞株におけるヒアルロン酸の検討2004
- Author(s)
  東福勝宏, 村山隆, 南周作, 横内雅博, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 骨肉腫細胞株における窒素含有ビスフォスフォネート剤リセドロネートによる増殖抑制効果の検討2004
- Author(s)
  村山隆, 横内雅博, 山下芳隆, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78・6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591500
[Journal Article] 骨肉腫におけるEGFR/Src/Cb1間シグナル伝達機構2004
- Author(s)
  山下芳隆, 横内雅博, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  日本整形外科学会雑誌 78巻6号
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Journal Article] 小児骨肉腫における有効な分子標的治療の検討2004
- Author(s)
  横内雅博, 山下芳隆, 村山隆, 南周作, 松永俊二, 米和徳, 小宮節郎
- Journal Title
  
  小児がん 41巻3号
  
  Pages: 675-675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591501
[Presentation] BMPシグナル標的遺伝子Atoh8欠損マウスの骨量は減少する.2017
- Author(s)
  八尋雄平，前田真吾，森川真大，鯉沼代造，篠原直弘，河村一郎，佐久間大輔, 石堂康弘，影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] BMP誘導因子Atoh8の欠損は骨量を減少させる.2017
- Author(s)
  八尋雄平，前田真吾，森川真大，鯉沼代造，佐久間大輔, 篠原直弘，松山金寛, 河村一郎，石堂康弘，影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] Loss of BMP-inducible gene Atoh8 in mice decreases bone mass.2017
- Author(s)
  Yahiro Y, Maeda S, Morikawa M, Koinuma D, Shinohara N, Matsuyama K, Sakuma D, Ishidou Y, Kageyama R, Miyazono K, Komiya S
- Organizer
  Joint Meeting of the Australian & New Zealand Bone & Mineral Society & the International Federation of Musculoskeletal Research Societies in Conjunction with the JSBMR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] HDAC阻害剤であるLBH589はFOSL1のdown regulationを介して未分化多型肉腫細胞の増殖を抑制する2017
- Author(s)
  齋藤嘉信, 瀬戸口啓夫, 中島隆之, 永野聡, 小宮節郎
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10452
[Presentation] 抗アレルギー薬tranilastは骨肉腫細胞株の細胞増殖を抑制し抗癌剤の効果を増強する2017
- Author(s)
  中島隆之、永野　聡、斎藤嘉信、瀬戸口啓夫、前田真吾、佐々木裕美、小宮節郎
- Organizer
  第34回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10452
[Presentation] TGF-betaにより活性化されるSMADとPEG10は互いに抑制しあい二層性の役割を持つ2017
- Author(s)
  篠原直弘, 前田真吾, 永野聡, 瀬戸口啓夫, 石堂康弘, 小宮節郎
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10452
[Presentation] Regulation of osteoblast differentiation by a novel BMP signaling target gene Atoh82017
- Author(s)
  Yuhei Hahiro, Shingo Maeda, Masato Morikawa, Daizo Koinuma, Naohiro Shinohara, Kanehiro Matsuyama, Ichiro Kawamura, Yasuhiro Ishidou, Ryoichiro Kageyama4, Kohei Miyazono, Setsuro Komiya
- Organizer
  Orthopaedic Research Society Annual Meeting 2017
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] BMPシグナル標的遺伝子Atoh8の骨代謝における役割.2017
- Author(s)
  八尋雄平，前田真吾，森川真大，鯉沼代造，篠原直弘，河村一郎，佐久間大輔, 石堂康弘，影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第18回運動器科学研究会
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] 脊柱後縦靭帯骨化症原因候補遺伝子CDC5Lの機能解析2017
- Author(s)
  104.前田真吾, 中島正宏, 河村一郎, 八尋雄平, 冨永博之, 石堂康弘, 武冨栄二, 池川志郎, 小宮節郎
- Organizer
  第3回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-17K10933
[Presentation] 脊柱後縦靭帯骨化症原因候補遺伝子CDC5Lの機能解析2017
- Author(s)
  1.前田真吾, 中島正宏, 河村一郎, 八尋雄平, 冨永博之, 石堂康弘, 武冨栄二, 池川志郎, 小宮節郎
- Organizer
  第3回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-15K10410
[Presentation] PEG10とTGF-βシグナルの軟骨肉腫表現型における役割2017
- Author(s)
  篠原直弘, 前田真吾, 八尋雄平, 河村一郎, 永野聡, 石堂康弘, 小宮節郎
- Organizer
  第90回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10452
[Presentation] 当科における悪性軟部腫瘍再発転移症例の治療経過と予後因子の解析2017
- Author(s)
  佐々木裕美、永野聡、瀬戸口啓夫、中島隆之、天辰愛弓、藤元祐介、小宮節郎
- Organizer
  第50回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-15K10452
[Presentation] TGF-βシグナルとPEG10の内軟骨腫と軟骨肉腫の診断鑑別マーカーとしての可能性と機能解析2016
- Author(s)
  篠原直弘, 前田真吾, 松山金寛, 八尋雄平, 今村勝之, 河村一郎, 瀬戸口啓夫, 永野聡, 横内雅博, 石堂康弘, 小宮節郎
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] BMPシグナルによる骨芽細胞分化制御2016
- Author(s)
  前田真吾, 八尋雄平, 森川真大, 鯉沼代造, 篠原直弘, 松山金寛, 河村一郎, 石堂康弘, 影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] Combination use of Hedgehog inhibitors prevent osteosarcoma growth synergistically2016
- Author(s)
  Saitoh Y., Setoguchi T., Nagata M., Nakamura S., Nagano S., Ishidou Y., Komiya S.
- Organizer
  62th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Orland USA
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462342
[Presentation] 骨肉腫におけるcasein kinase２の発現と機能解析2016
- Author(s)
  高橋健吾、瀬戸口啓夫、斎藤嘉信、中島隆之、鶴亜里紗、永野聡、富永博之、石堂康弘、小宮節郎
- Organizer
  第３１回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K10452
[Presentation] Expression of Paternally Expressed Gene 10 (PEG10) is Negatively Associated with Malignancy Grading of Human Chondrosarcoma; the Role of PEG10 to Prevent Bone Morphogenetic Protein (BMP)-p38 MAPK Signaling-mediated Induction of Matrix Metalloproteinase (MMP)-1 to Suppress the Invasive Activity2016
- Author(s)
  Naohiro Shinohara, Shingo Maeda, Kanehiro Matsuyama, Yuhei Yahiro, Katsuyuki Imamura, Ichiro Kawamura, Takao Setoguchi, Satoshi Nagano, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  Orthopaedic Research Society Annual Meeting 2016
- Place of Presentation
  Orlando(USA)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] PEG10はBMP-p38 MAPK経路を介する軟骨肉腫細胞の浸潤を制御する2016
- Author(s)
  篠原直弘, 前田真吾, 松山金寛, 八尋雄平, 今村　勝行, 横内雅博, 永野聡, 石堂康弘, 小宮節郎
- Organizer
  第２９回日本軟骨代謝学会
- Place of Presentation
  広島大学医学部 (広島県　広島市)
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] Atoh8, a Direct Target Gene of BMP-Smad1/5/8 Signaling, Negatively Regulates Osteoblastic Bone Formation2016
- Author(s)
  Yuhei Hahiro, Shingo Maeda, Masato Morikawa, Daizo Koinuma, Naohiro Shinohara, Kanehiro Matsuyama, Ichiro Kawamura, Yasuhiro Ishidou, Ryoichiro Kageyama, Kohei Miyazono, Setsuro Komiya
- Organizer
  Orthopaedic Research Society Annual Meeting 2016
- Place of Presentation
  Orlando(USA)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] 軟骨肉腫においてPEG10はTGFとBMPシグナルにより発現制御され腫瘍進展に影響する2016
- Author(s)
  篠原直弘　前田真吾　松山金寛　八尋雄平　今村勝行　河村一郎　永野聡　瀬戸口啓夫　石堂康弘　小宮節郎
- Organizer
  第132回西日本整形・災害外科学会学術集会
- Place of Presentation
  かごしま県民交流センター（鹿児島県・鹿児島市）
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] 内軟骨腫と軟骨肉腫におけるTGF-βシグナルとPEG10の発現および機能解析2016
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、今村勝行、河村一郎、瀬戸口啓夫、永野聡、石堂康弘、小宮節郎
- Organizer
  第３１回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K10452
[Presentation] Expression of Paternally Expressed Gene 10 (PEG10) is Negatively Associated with Malignancy Grading of Human Chondrosarcoma; the Role of PEG10 to Prevent Bone Morphogenetic Protein (BMP)-p38 MAPK Signaling-mediated Induction of Matrix Metalloproteinase (MMP)-1 to Suppress the Invasive Activity2016
- Author(s)
  Naohiro Shinohara, Shingo Maeda, Kanehiro Matsuyama, Yuhei Yahiro, Katsuyuki Imamura, Ichiro Kawamura, Takao Setoguchi, Satoshi Nagano, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  Orthopaedic Research Society Annual Meeting 2016
- Place of Presentation
  Orlando, USA
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] 新規BMPシグナル標的遺伝子Atoh8による骨芽細胞分化制御2016
- Author(s)
  八尋雄平, 前田真吾, 森川真大, 鯉沼代造, 篠原直弘, 河村一郎,石堂康弘, 影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] PEG10はBMP-p38 MAPK経路を介する軟骨肉腫細胞の浸潤を制御する2016
- Author(s)
  篠原直弘, 前田真吾, 松山金寛, 八尋雄平, 今村　勝行, 横内雅博, 永野聡, 石堂康弘, 小宮節郎
- Organizer
  第２９回日本軟骨代謝学会
- Place of Presentation
  広島大学医学部(広島県　広島市)
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] BMP誘導遺伝子Atoh8の骨芽細胞分化における機能2016
- Author(s)
  八尋雄平, 前田真吾, 森川真大, 鯉沼代造, 篠原直弘, 河村一郎,石堂康弘, 影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第17回運動器科学研究会
- Place of Presentation
  大阪大学中之島センター佐治敬三メモリアルホール・大阪リーガロイヤルホテル(大阪府・大阪市）
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] TGF-β signaling and PEG10 exhibit mutually opposite expression pattern and roles in cell invasion of chondrosarcoma2016
- Author(s)
  Naohiro Shinohara, Shingo Maeda, Satoshi Nagano, Takao Setoguchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  第75回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] 新規BMPシグナル標的遺伝子Atoh8による骨芽細胞分化制御2016
- Author(s)
  八尋雄平, 前田真吾, 森川真大, 鯉沼代造, 篠原直弘, 松山金寛, 河村一郎, 石堂康弘, 影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第29回　日本軟骨代謝学会
- Place of Presentation
  広島大学医学部(広島県　広島市)
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] BMPシグナル標的遺伝子Atoh8は骨芽細胞分化を抑制する2015
- Author(s)
  八尋雄平, 前田真吾, 森川真大, 鯉沼代造, 篠原直弘, 松山金寛, 河村一郎, 横内雅博, 石堂康弘, 影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第１６回運動器科学研究会
- Place of Presentation
  みなみホール(鹿児島県　鹿児島市)
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] 新規BMPシグナル標的遺伝子Atoh8は骨芽細胞分化成熟を抑制する2015
- Author(s)
  八尋雄平、前田真吾、篠原直弘、横内雅博、河村一郎、石堂康弘、小宮節郎
- Organizer
  第３０回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場(富山県　富山市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] BMPシグナル標的遺伝子Atoh8は骨芽細胞分化を抑制する2015
- Author(s)
  八尋雄平、前田真吾、篠原直弘、横内雅博、河村一郎、石堂康弘、小宮節郎
- Organizer
  第３３回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京都　新宿区)
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] BMP誘導性インプリンティング遺伝子PEG10は p38経路を介して軟骨肉腫細胞の浸潤能を抑制する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、横内雅博、石堂康弘、小宮節郎
- Organizer
  第１６回運動器科学研究会
- Place of Presentation
  みなみホール(鹿児島県　鹿児島市)
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMP誘導性のPEG10は軟骨肉腫細胞浸潤能増強を抑制する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３０回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場 (富山県　富山市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMP誘導性インプリンティング遺伝子PEG10は p38経路を介して軟骨肉腫細胞の浸潤能を抑制する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、横内雅博、石堂康弘、小宮節郎
- Organizer
  第１６回運動器科学研究会
- Place of Presentation
  みなみホール(鹿児島県　鹿児島市)
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] BMPシグナル標的遺伝子Atoh8による骨芽細胞分化抑制2015
- Author(s)
  八尋雄平, 前田真吾, 森川真大, 鯉沼代造, 篠原直弘, 松山金寛, 河村一郎, 横内雅博, 石堂康弘, 影山龍一郎, 宮園浩平, 小宮節郎
- Organizer
  第３８回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県　神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] BMPにより増強される軟骨肉腫細胞の浸潤能を発現誘導されたPEG10は制御する2015
- Author(s)
  篠原直弘,前田真吾,八尋雄平,今村　勝行,横内雅博,河村一郎,石堂康弘,小宮節郎
- Organizer
  第３３回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] BMP誘導性インプリンティング遺伝子PEG10は軟骨肉腫細胞においてBMPにより活性化されたp38 MAPK経路とMMPs発現抑制を介して浸潤能を制御する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、今村勝行、横内雅博、永野聡、石堂康弘、小宮節郎
- Organizer
  第３８回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫県　神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMPシグナル標的遺伝子Atoh8のノックダウンは骨芽細胞分化を促進する2015
- Author(s)
  八尋雄平、前田真吾、篠原直弘、松山金寛、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第１回　骨免疫学会
- Place of Presentation
  ホテルブリーズベイマリーナ(沖縄県　宮古島市)
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K10486
[Presentation] BMPにより増強される軟骨肉腫細胞の浸潤能を発現誘導されたPEG10は制御する2015
- Author(s)
  篠原直弘,前田真吾,八尋雄平,今村　勝行,横内雅博,河村一郎,石堂康弘,小宮節郎
- Organizer
  第３３回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京都　新宿区)
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMP誘導性のPEG10は軟骨肉腫細胞浸潤能増強を抑制する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３０回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場(富山県　富山市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] BMP誘導性インプリンティング遺伝子PEG10は軟骨肉腫細胞においてBMPにより活性化されたp38 MAPK経路とMMPs発現抑制を介して浸潤能を制御する2015
- Author(s)
  篠原直弘、前田真吾、松山金寛、八尋雄平、今村勝行、横内雅博、永野聡、石堂康弘、小宮節郎
- Organizer
  第３８回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫県　神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] BMPシグナルにより誘導されるSmpd3はセラミド-Akt経路を介して軟骨細胞分化成熟を抑制する2014
- Author(s)
  前田　真吾、栫　博則、篠原　直弘、松山　兼寛、今村　勝行、河村　一郎、横内　雅博、石堂康弘、小宮節郎
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都府医師会館, 京都市
- Data Source
  KAKENHI-PROJECT-25462376
[Presentation] インプリンティング遺伝子Peg10の軟骨細胞分化における役割2014
- Author(s)
  篠原直弘、前田真吾、今村勝行、松山金寛、横内雅博、石堂康弘、小宮節郎
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] BMPシグナルにより誘導されるSmpd3はセラミド-Akt経路を介して軟骨細胞分化成熟を抑制する2014
- Author(s)
  前田真吾、栫博則、篠原直弘、松山兼寛、今村勝行、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Alg2, identified as a downstream mediator of Schnurri 3, inhibits function of Runx2 and osteoblast differentiation2014
- Author(s)
  Imamura K, Maeda S, Kawamura I, Ishidou Y, Komiya S, Yokouchi M
- Organizer
  1st Asia-Pacific Bone and Mineral Research Meeting with Australian and New Zealand Bone and Mineral Society (ANZBMS) 22nd Annual Scientific Meeting
- Place of Presentation
  Perth, Australia
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Human immunodeficiency virus type I　enhancer binding protein 3 (Hivep3)の下流として同定したAsparagine-linked glycosylation 2 (Alg2)は骨芽細胞と軟骨細胞の分化を調節する2014
- Author(s)
  今村勝行、前田真吾、篠原直弘、松山金寛、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Human immunodeficiency virus type I enhancer binding protein 3 (Hivep3)の下流として同定したAsparagine-linked glycosylation 2 (Alg2)は骨芽細胞と軟骨細胞の分化を調節する2014
- Author(s)
  村勝行、前田真吾、篠原直弘、松山金寛、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Smpd3 prevents maturation and expression of hyaluronan synthase 2 in ATDC5 chondrocytes2013
- Author(s)
  Kakoi H, Maeda S, Imamura K, Kawamura I, Ishidou Y, Yokouchi M, Komiya S
- Organizer
  ESCEO13-IOF Rome 2013
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Smpd3 prevents maturation and expression of hyaluronan synthase 2 in ATDC5 chondrocytes2013
- Author(s)
  Kakoi H, Maeda S, Imamura K, Kawamura I, Ishidou Y, Yokouchi M, Komiya S
- Organizer
  ESCEO13-IOF Rome 2013
- Place of Presentation
  Rome Cavalieri, Rome, Italy
- Data Source
  KAKENHI-PROJECT-25462376
[Presentation] Smpd3/nSMase2はセラミドを介したAktシグナル経路阻害によりATDC5軟骨細胞分化とヒアルロン酸合成酵素Has2の発現を抑制する2013
- Author(s)
  栫博則、前田真吾、松山兼寛、今村勝行、河村一郎、篠原直弘、横内雅博、石堂康弘、小宮節郎
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ, 千葉市
- Data Source
  KAKENHI-PROJECT-25462376
[Presentation] 三酸化ヒ素はGLIの転写を抑制しDNA損傷を介して骨肉腫の増殖を阻害する2013
- Author(s)
  中村俊介, 瀬戸口啓夫, 永尾宗子, 永野聡, 棈松昌彦, 小宮節郎
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市幕張
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] The roles of Schnurri family in differentiation of osteoblasts and chondrocytes2013
- Author(s)
  Katsuyuki Imamura, Shingo Maeda, Ishidou Yasuhiro, Masahiro Yokouchi, Setsuro Komiya
- Organizer
  Australian and New Zealand Bone and Mineral Society 23rd ANNUAL SCIENTIFIC MEETING
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] 脊髄損傷における神経ネットワークの再構築2013
- Author(s)
  棈松昌彦、藤元祐介、井尻幸成、山元拓哉、米和徳、小宮節郎
- Organizer
  第４２回日本脊椎脊髄病学会
- Place of Presentation
  沖縄
- Invited
- Data Source
  KAKENHI-PROJECT-24592203
[Presentation] Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation2013
- Author(s)
  S Nakamura, S Nagano, H Nagao, M Abematsu, M Yokouchi, Y Ishidou, S Komiya, T Setoguchi
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] BMP signaling induces sphingomyelin phosphodiesterase 3 to suppress chondrocyte maturation and expression of hyaluronan synthase 2 in ATDC5 chondrocytes2013
- Author(s)
  Shingo Maeda, Hironori Kakoi, Kanehiro Matsuyama, Ichiro Kawamura, Katsuyuki Imamura, Naohiro Shinohara, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  TGF-β meeting in Uppsala
- Place of Presentation
  Uppsala University, Uppsala, Sweden
- Data Source
  KAKENHI-PROJECT-25462376
[Presentation] 骨軟骨細胞分化におけるSchnurri family の役割2013
- Author(s)
  前田真吾、河村一郎、石堂康弘、横内雅博、小宮節郎
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  豊中市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Asparagine-linked glycosylation 2 homolog, identified as a downstream target of Schnurri-3, cell-autonomously regulates differentiation of osteoblasts and chondrocytes.2013
- Author(s)
  Imamura, Katsuyuki; Maeda, Shingo; Kawamura, Ichiro; Yokouchi, Masahiro; Ishidou, Yasuhiro; Komiya, Setsuro
- Organizer
  Orthopaedic Research Society 2013 Annual Meeting
- Place of Presentation
  アメリカ合衆国、サンアントニオ市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] BMP-2シグナルはneutral sphingomyelinase 2の誘導によるAktシグナル経路の抑制を介して軟骨細胞分化成熟を制御する2013
- Author(s)
  前田真吾、栫博則、松山金寛、河村一郎、今村勝行、篠原直弘、永野聡、瀬戸口啓夫、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場, 神戸市
- Data Source
  KAKENHI-PROJECT-25462376
[Presentation] Neutral Sphingomyelinase 2 Is Increased During BMP-induced Differentiation of ATDC5 Chondrocytes to Suppress the Maturation as a Negative Feedback Mechanism2013
- Author(s)
  Shingo Maeda, Hironori Kakoi, Kanehiro Matsuyama, Katsuyuki Imamura, Ichiro Kawamura, Naohiro Shinohara, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  The American Society for Bone and Mineral Rresearch 2013
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] 脊髄髄膜腫におけるMRI画像所見による新規脊髄評価法と術後臨床成績の検討2013
- Author(s)
  棈松昌彦、井尻幸成、川内義久、富村奈津子、米和徳、小宮節郎
- Organizer
  第４２回日本脊椎脊髄病学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-24592203
[Presentation] BMP signaling induces sphingomyelin phosphodiesterase 3 to suppress chondrocyte maturation and expression of hyaluronan synthase 2 in ATDC5 chondrocytes2013
- Author(s)
  Shingo Maeda, Hironori Kakoi, Kanehiro Matsuyama, Ichiro Kawamura, Katsuyuki Imamura, Naohiro Shinohara, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  TGF-β meeting in Uppsala
- Place of Presentation
  Uppsala, Sweden
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] インプリンティング遺伝子Peg10の骨芽細胞と軟骨細胞の分化への関与2013
- Author(s)
  篠原直弘、前田真吾、今村勝行、松山金寛、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] The roles of Schnurri family in differentiation of osteoblasts and chondrocytes2013
- Author(s)
  Katsuyuki Imamura, Shingo Maeda, Ishidou Yasuhiro, Masahiro Yokouchi, Setsuro Komiya
- Organizer
  Australian and New Zealand Bone and Mineral Society 23rd ANNUAL SCIENTIFIC MEETING
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Neutral Sphingomyelinase 2 Is Increased During BMP-induced Differentiation of ATDC5 Chondrocytes to Suppress the Maturation as a Negative Feedback Mechanism2013
- Author(s)
  Shingo Maeda, Hironori Kakoi, Kanehiro Matsuyama, Katsuyuki Imamura, Ichiro Kawamura, Naohiro Shinohara, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  The American Society for Bone and Mineral Rresearch 2013
- Place of Presentation
  Baltimore Covention Center, Baltimore, USA
- Data Source
  KAKENHI-PROJECT-25462376
[Presentation] BMP-2シグナルはneutral sphingomyelinase 2の誘導によるAktシグナル経路の抑制を介して軟骨細胞分化成熟を制御する2013
- Author(s)
  前田真吾、栫博則、松山金寛、河村一郎、今村勝行、篠原直弘、永野聡、瀬戸口啓夫、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] The role of Schnurri family in differentiation of osteoblasts and chondrocytes2013
- Author(s)
  Katsuyuki Imamura, Shingo Maeda, Ichiro Kawamura, Yasuhiro Ishidou, Masahiro Yokouchi, Setsuro Komiya
- Organizer
  国際骨代謝学会・日本骨代謝学会第2回合同国際会議
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] GLI2によるRPS3発現を介した骨肉腫転移能亢進2013
- Author(s)
  瀬戸口啓夫, 永尾宗子, 永野聡, 中村俊介, 横内雅博, 棈松雅彦, 石堂康弘, 小宮節郎
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市幕張
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] Alg2 is induced by Schnurri-3 to inhibit transcriptional activity of Runx2 and osteoblast differentiation2013
- Author(s)
  Imamura K, Maeda S, Kawamura I, Ishidou Y, Yokouchi M and Komiya S
- Organizer
  ESCEO13-IOF Rome 2013
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] GF-βsignaling is highly active to induce SnoN in ectopically hypertrophying chondrocytes in degenerating osteoarthritis cartilage. - Evaluating SnoN as a molecular target for regulating progression of chondrocyte maturation -2013
- Author(s)
  Kawamura, I ; Maeda, S ; Imamura, K ; Yokouchi, M ; Ishidou, Y ; Komiya S
- Organizer
  Orthopaedic Research Society 2013 Annual Meeting
- Place of Presentation
  San Antonio, TX, USA
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] インプリンティング遺伝子Peg10はBMP-2誘導の骨・軟骨細胞分化を促進する2013
- Author(s)
  篠原直弘、前田真吾、今村勝行、松山金寛、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-25462343
[Presentation] TGF-β signaling is highly active to induce SnoN in ectopically hypertrophying chondrocytes in degenerating osteoarthritis cartilage. - Evaluating SnoN as a molecular target for regulating progression of chondrocyte maturation -2013
- Author(s)
  Kawamura, I, Maeda, S, Imamura, K, Yokouchi, M, Ishidou, Y, Komiya, S
- Organizer
  Orthopaedic Research Society 2013 Annual Meeting
- Place of Presentation
  アメリカ合衆国、サンアントニオ市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Schnurriファミリーによる骨芽細胞分化調節の多様性2013
- Author(s)
  今村勝行、前田真吾、河村一郎、石堂康弘、横内雅博、小宮節郎
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Smpd3/nSMase2 suppresses Akt signaling pathway to inhibit chondrogenic differentiation and expression of Has2 in ATDC5 cells2013
- Author(s)
  Hironori Kakoi, Shingo Maeda, Ichiro Kawamura, Katsuyuki Imamura, Naohiro Shinohara, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  国際骨代謝学会・日本骨代謝学会　第２回合同国際会議
- Place of Presentation
  神戸国際会議場, 神戸市
- Data Source
  KAKENHI-PROJECT-25462376
[Presentation] iPS由来神経幹細胞を用いた脊髄損傷再生治療2013
- Author(s)
  棈松昌彦、藤元祐介、井尻幸成、山元拓哉、米和徳、小宮節郎
- Organizer
  第２８回　日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Invited
- Data Source
  KAKENHI-PROJECT-24592203
[Presentation] Schnurri ファミリーによる骨芽細胞分化調節の多様性2013
- Author(s)
  今村勝行、前田真吾、河村一郎、石堂康弘、横内雅博、小宮節郎
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] 軟骨細胞におけるC/EBPβによるGADD45βの直接的な制御2013
- Author(s)
  嶋田博文、井尻;幸成、小宮節郎、土持兼之
- Organizer
  第28回　日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市幕張メッセ
- Data Source
  KAKENHI-PROJECT-23390369
[Presentation] Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation2013
- Author(s)
  S Nakamura, S Nagano, H Nagao, A Tsuru , Y Ishidou, M Yokouchi, M Abematsu, T Yamamoto, S Komiya, T Setoguchi
- Organizer
  Orthopedic Research Society 2013 Annual Meeting
- Place of Presentation
  San Antonio, TX, USA
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] The role of Schnurri family in differentiation of osteoblasts and chondrocytes2013
- Author(s)
  Katsuyuki Imamura, Shingo Maeda, Ichiro Kawamura, Yasuhiro Ishidou, Masahiro Yokouchi, Setsuro Komiya
- Organizer
  国際骨代謝学会・日本骨代謝学会　第２回合同国際会議
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Asparagine-linked glycosylation 2 homolog, identified as a downstream target of Schnurri-3, cell-autonomously regulates differentiation of osteoblasts and chondrocytes2013
- Author(s)
  Imamura, Katsuyuki ; Maeda, Shingo ; Kawamura, Ichiro ; Yokouchi, Masahiro ; Ishidou, Yasuhiro ; Komiya, Setsuro
- Organizer
  Orthopaedic Research Society 2013 Annual Meeting
- Place of Presentation
  San Antonio, TX, USA
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] 超音波と Bubble Liposome を併用したドキソルビシンのマウス骨肉腫細胞に対する抗腫瘍効果2012
- Author(s)
  上野宜功, 園田祥三, 鈴木亮, 横内雅博, 川添泰臣, 丸山一雄, 坂本泰二, 小宮節郎
- Organizer
  日本生体電気・物理刺激研究会
- Place of Presentation
  於鹿児島
- Data Source
  KAKENHI-PROJECT-22591662
[Presentation] 軟骨細胞肥大分化成熟期における TGF-βシグナルとBMPシグナルのクロストーク2012
- Author(s)
  河村一郎, 前田真吾, 今村勝行,　横内雅博, 石堂康弘, 小宮節郎
- Organizer
  第３０回日本骨代謝学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] A new method for determining surgical margin in soft tissue sarcoma using a combination of CT and FDG-positron emission tomography2012
- Author(s)
  S Nagano, M Yokouchi, M　Terahara, H Sasaki, H Shimada, R Hidaka, H　Tokumoto, S Komiya
- Organizer
  22nd Japan-Korean Combined Orthopaedic Symposium
- Place of Presentation
  日光市
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] Pharmacological inhibition of GLI transcription prevents human osteosarcoma growth2012
- Author(s)
  Setoguchi T., Nakamura S., Nagao H., Nagano S., Abematsu M., Komiya S.
- Organizer
  22nd Japan-Korean Combined Orthopaedic Symposium
- Place of Presentation
  日光市
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] Schnurri-3 の下流因子として同定した糖転移酵素Alg2 の骨芽細胞分化と軟骨細胞分化における役割2012
- Author(s)
  今村勝行,河村一郎,石堂康弘,前田真吾,小宮節郎, 横内雅博
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Schnurri-3の下流因子として同定したAlg2は Runx2機能を阻害し骨芽細胞分化を抑制する2012
- Author(s)
  今村勝行、前田真吾、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第３０回日本骨代謝学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Schnurri-3 の下流因子として同定したAlg2 はRunx2 機能を阻害し骨芽細胞分化を抑制する2012
- Author(s)
  今村勝行,前田真吾,河村一郎,石堂康弘, 横内雅博,小宮節郎
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] 軟骨細胞肥大分化成熟期におけるTGF-βシグナルとBMPシグナルのクロストーク2012
- Author(s)
  河村一郎,前田真吾,今村勝行,石堂康弘, 横内雅博,小宮節郎
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  東京都 (東京大学分子細胞生物学研究所骨関節疾患制御研究分野)
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Endogenous TGF-β-induced SnoN prevents BMP signaling and subsequent hypertrophic differentiation of chondrocytes2012
- Author(s)
  Kawamura I, Maeda S, Imamura K, Ishidou Y, Komiya S, Yokouchi M
- Organizer
  The 22nd Japanese-Korean Combined Or thopaedic Symposium
- Place of Presentation
  Nikko-Tochigi, Japan
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] 骨軟部肉腫に対する新規分子標的治療2012
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  日本整形外科学会基礎学術集会シンポディウム
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-22591663
[Presentation] 横紋筋肉腫におけるGOLPH3遺伝子の高発現とその機能解析Functional analysis of over-expressed GOLPH3 in rhabdomyosarcoma2012
- Author(s)
  救仁郷修、瀬戸口啓夫、松野下幸弘、佐々木裕美、永尾宗子、小宮節郎
- Organizer
  第45回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-23592195
[Presentation] 骨肉腫転移におけるHEY1の役割について2012
- Author(s)
  鶴　亜里紗、松野下　幸弘、永尾宗子、永野　聡、横内雅博、棈松昌彦、石堂康弘、小宮節郎、瀬戸口啓夫
- Organizer
  第45回日本整形外科学会骨軟部腫瘍学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] 当科を受診した転移性骨腫瘍患者の解析－原発巣診断に影響する因子2012
- Author(s)
  嶋田博文、永野　聡、横内雅博、佐々木裕美、吉井理一郎、有島善也、小宮節郎
- Organizer
  第45回日本整形外科学会骨軟部腫瘍学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] 転移性骨腫瘍患者の予後に関する因子の解析 ~骨関連事象の重要性~2012
- Author(s)
  嶋田博文, 永野　聡, 横内雅博, 佐々木裕美, 佐久間大輔, 瀬戸口　啓夫, 小宮　節郎
- Organizer
  第124回西日本整形・災害外科学会学術集会
- Place of Presentation
  別府市
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] 軟骨細胞肥大分化過程におけるTGF-βシグナル標的遺伝子SnoNの機能解析と変形性関節症との関連2012
- Author(s)
  河村一郎,前田真吾,今村勝行,石堂康弘,小宮節郎, 横内雅博
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋市 (名古屋市立大学大学院医学研究科整形外科学)
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] SnoN mediates a crosstalk between TGF-β and BMP signaling to suppress hypertrophic maturation of chondrocytes2012
- Author(s)
  Ichiro Kawamura, Shingo Maeda, Katsuyuki Imamura, Masahiro Yokouchi, Yasuhiro Ishidou, and Setsuro Komiya
- Organizer
  1st Asia-Pacific Bone and Mineral Research Meeting with the ANZBMS 22nd Annual Scientific Meeting
- Place of Presentation
  オーストラリア、パース市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] GLI2の骨肉腫転移・浸潤への機能の解析2012
- Author(s)
  瀬戸口啓夫, 永尾宗子, 永野聡, 横内雅博, あべ松昌彦, 小宮節郎
- Organizer
  第45回日本整形外科学会骨軟部腫瘍学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] Schnurri-3の下流因子として同定した糖転移酵素 Alg2は骨芽細胞分化を抑制する2012
- Author(s)
  今村勝行、前田真吾、河村一郎、横内雅博、石堂康弘、小宮節郎
- Organizer
  第２７回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Schnurri-3 の下流因子として同定した糖転移酵素Alg2 は骨芽細胞分化を抑制する2012
- Author(s)
  今村勝行,前田真吾,河村一郎,石堂康弘, 横内雅博,小宮節郎
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] SnoN mediates a signal crosstalk between TGF-β and BMP pathways in chondrocytes to prevent hypertrophic maturation2012
- Author(s)
  Shingo Maeda, Ichiro Kawamura, Katsuyuki Imamura, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  日本学術振興会　先端研究拠点事業　国際戦略型　TGF-β　ファミリーシグナル　国際共同研究拠点　第2回国際シンポジウム
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] 変形性関節症軟骨に発現するSnoNはTGF-βとBMPシグナルのクロストークを形成して肥大軟骨分化過程を抑制する2012
- Author(s)
  河村　一郎、前田　真吾、今村　勝行、横内　雅博、石堂　康弘、小宮　節郎
- Organizer
  第２７回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] SnoN mediates a crosstalk between TGF-βand BMP signaling to suppress hypertrophic maturation of chondrocytes2012
- Author(s)
  Kagoshima, Japan Kawamura I, Maeda S, Imamura K, Ishidou Y, Komiya S
- Organizer
  1st Asia-Pacific Bone and Mineral Research Meeting with Australian and New Zealand Bone and Miner al Society (ANZBMS) 22nd Annual Scientific Meeting
- Place of Presentation
  Perth, Australia
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] SnoN prevents BMP-induced hypertrophic conversion of chondrocytes2012
- Author(s)
  Kawamura I, Ishidou Y, Imamura K, Komiya S, Maeda S, Yokouchi M
- Organizer
  58^<th> Annual Meeting of the Or thopaedic Research Society
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Alg2, identified as a downstream mediator of Schnurri-3, inhibits function of Runx2 and osteoblast differentiation2012
- Author(s)
  Imamura K, Maeda S, Kawamura I, Ishidou Y, Yokouchi M, Komiya S
- Organizer
  1st Asia-Pacific Bone and Mineral Research Meeting with the ANZBMS 22nd Annual Scientific Meeting
- Place of Presentation
  オーストラリア、パース市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation2012
- Author(s)
  S Nakamura, S Nagano, H Nagao, A Tsuru, Y Ishidou, M Yokouchi, M Abematsu, T Yamamoto, S Komiya, and T Setoguchi
- Organizer
  第35回　日本分子生物学会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] Mannosyltransferase Alg2, identified as a downstream mediator of Schnurri-3, is involved in differentiation of osteoblast and chondrocyte.2012
- Author(s)
  Katsuyuki Imamura, Shingo Maeda, Ichiro Kawamura, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya.
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] SnoN mediates a signal crosstalk between TGF-βand BMP pathways in chondrocytes to prevent hypertrophic maturation2012
- Author(s)
  Maeda S, Kawamura I, Imamura K, Ishidou Y, Komiya S, Yokouchi M
- Organizer
  The 2nd Inter national Symposium by J SPS Core-to Core Program"Cooperative Inter national Fr amework in TGF-βFamily signaling"
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] SnoN, a target of TGF-β signaling, inhibits BMP-induced hypertrophic conversion of chondrocytes.2012
- Author(s)
  Ichiro Kawamura, Shingo Maeda, Katsuyuki Imamura,　 Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya.
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] chnurri-3 の下流で誘導されるAlg2 は骨芽細胞と軟骨細胞の分化を調節する2012
- Author(s)
  今村勝行,前田真吾,河村一郎,石堂康弘,小宮節郎, 横内雅博
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Functional analysis of HEY1 in osteosarcoma metastasis2012
- Author(s)
  Setoguchi T., Nagano S., and Komiya S.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] Alg2, identified as a downstream mediator of Schnurri-3, regulates differentiation of osteoblasts and chondrocytes negatively and positively, respectively.2012
- Author(s)
  Katsuyuki Imamura,　Shingo Maeda, Ichiro Kawamura, Masahiro Yokouchi, Yasuhiro Ishidou, Setsuro Komiya
- Organizer
  第３５回日本分子生物学会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] TGF-βシグナル標的遺伝子SnoNの軟骨細胞成熟過程における役割と変形性関節症との関連2012
- Author(s)
  河村一郎,石堂康弘,今村勝行,前田真吾,小宮節郎, 横内雅博
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  名古屋市 (藤田保健衛生大学医学部整形外科学教室)
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Hedgehog pathwayの薬理学的抑制によるヒト骨肉腫の増殖抑制効果2012
- Author(s)
  中村俊介, 永尾宗子、永野聡、横内雅博、あべ松昌彦、小宮節郎、瀬戸口啓夫
- Organizer
  第45回日本整形外科学会骨軟部腫瘍学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] 軟骨細胞分化成熟におけるSnoNの発現と機能2011
- Author(s)
  河村一郎,今村勝行,石堂康弘,前田真吾, 横内雅博,小宮節郎
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Role of GLI2 in the growth of human osteosarcoma.2011
- Author(s)
  瀬戸口啓夫, 小宮節郎
- Organizer
  56th Annual Meeting of Orthopaedic Research Society, Long Beach
- Place of Presentation
  CA, USA
- Year and Date
  2011-01-13
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] 超音波を使用した新規抗癌剤デリバリーシステムについての実験的検討2011
- Author(s)
  横内雅博, 上野宜功, 川添泰臣, 永野聡, 小宮節郎, 園田祥三, 坂本泰二, 鈴木亮, 丸山和雄
- Organizer
  日本癌治療学会
- Place of Presentation
  於名古屋
- Data Source
  KAKENHI-PROJECT-22591662
[Presentation] Mannosyltransferase Alg2 Is a downstream Regulator of Schnurri-3 in Osteoblast Differentiation.2011
- Author(s)
  Katsuyuki Imamura, Yasuhiro Ishidou, Ichiro Kawamura, Masahiro Yokouchi, Setsuro Komiya, Shingo Maeda.
- Organizer
  American Society for Bone and Mineral Research 2011 Annual Meeting
- Place of Presentation
  San Diego, CA, USA.
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] 骨芽細胞分化を抑制するSchnurri-3は軟骨細胞分化を促進する2011
- Author(s)
  今村勝行, 石堂康弘, 河村一郎, 横内雅博, 小宮節郎, 前田真吾
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Schnurri-3の下流遺伝子として同定した糖転移酵素Alg2は骨芽細胞分化を抑制する2011
- Author(s)
  今村勝行, 石堂康弘, 河村一郎, 横内雅博, 小宮節郎, 前田真吾
- Organizer
  第２９回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] SnoN mediates a signal crosstalk between TGF-β and BMP in maturating chondrocytes.2011
- Author(s)
  Ichiro Kawamura, Yasuhiro Ishidou, Katsuyuki Imamura, Masahiro Yokouchi, Shingo Maeda, Setsuro Komiya.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] 軟骨細胞分化成熟におけるSnoNの発現と機能2011
- Author(s)
  河村一郎, 石堂康弘, 今村勝行, 横内雅博, 小宮節郎, 前田真吾
- Organizer
  第２９回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] ヒト骨肉腫におけるGLI2の機能解析2011
- Author(s)
  中村俊介、瀬戸口啓夫、永尾宗子、永野聡、小宮節郎
- Organizer
  第122回西日本整形・災害外科学会
- Place of Presentation
  熊本市
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] ヒト骨肉腫におけるGLI2の強発現とGLI2をターゲットにした骨肉腫治療の可能性2011
- Author(s)
  永尾宗子、小宮節郎、瀬戸口啓夫
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] ヒト骨肉腫におけるGLI2の機能解析2011
- Author(s)
  瀬戸口啓夫、永尾宗子、廣津匡隆、永野聡、小宮節郎
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  群馬県前橋市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21591919
[Presentation] Oncogene SnoNの軟骨細胞成熟肥大過程における機能解析と変形性関節症との関連2011
- Author(s)
  河村一郎,今村勝行,山元拓哉,善明美千久,井尻幸成, 石堂康弘,前田真吾, 小宮節郎
- Organizer
  第24回日本軟骨代謝学会
- Place of Presentation
  福岡市 (九州大学医学部整形外科)
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Schnurri-3 の下流因子として同定した糖転移酵素Alg2 は骨芽細胞分化を抑制する2011
- Author(s)
  今村勝行,河村一郎,横内雅博, 小宮節郎, 石堂康弘,前田真吾
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] 軟骨細胞肥大分化過程におけるSnoNの機能解析と変形性関節症との関連2011
- Author(s)
  河村一郎,今村勝行,小宮節郎, 石堂康弘,前田真吾, 横内雅博
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋市(群馬大学大学院医学系研究科器官機能制御学講座整形外科学)
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] Condrocyte differentiation is suppressed by knock-down of Schnurri-3 gene in vitro2011
- Author(s)
  Maeda S, Kawamura I, Ishidou Y, Setoguchi T, Yamamoto T, Zenmyo M, Ijiri K, Komiya S
- Organizer
  57^<th> Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Long Beach, CA, USA
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] Mannosyltransferase Alg2 regulates differentiation of osteoblasts and chondrocytes.2011
- Author(s)
  Katsuyuki Imamura, Yasuhiro Ishidou, Ichiro Kawamura, Masahiro Yokouchi, Shingo Maeda, Setsuro Komiya.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] SnoN mediateds a signal crosstalk between TGF-βand BMP in maturating chondrocytes2011
- Author(s)
  Kawamura I, Imamura K, Yokouchi M, Komiya S, Ishidou Y, Maeda S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市 (学習院大学理学部)
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] 骨芽細胞分化を抑制するSchnurri-3 は軟骨細胞分化を促進する2011
- Author(s)
  今村勝行,河村一郎,小宮節郎, 石堂康弘,前田真吾, 横内雅博
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  群馬県前橋市
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] TGF-β-induced SnoN Prevents BMP Signaling and Hypertrophic Conversion of Chondrocytes.2011
- Author(s)
  Ichiro Kawamura, Yasuhiro Ishidou, Katsuyuki Imamura, Masahiro Yokouchi, Setsuro Komiya, Shingo Maeda.
- Organizer
  American Society for Bone and Mineral Research 2011 Annual Meeting
- Place of Presentation
  San Diego, CA, USA.
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] TGF-βsignaling induces SnoN to suppress BMP-induced hypertrophic maturation of chondrocytes2011
- Author(s)
  Maeda S, Kawamura I, Ishidou Y, Imamura K, Yokouchi M, Komiya S
- Organizer
  1^<st> Bio-Rheumatology Inter national Congress
- Place of Presentation
  Urayasu, Japan
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] 骨芽細胞と軟骨細胞の分化におけるSchnurri-3 の役割2011
- Author(s)
  前田真吾,今村勝行,石堂康弘,河村一郎,横内雅博,小宮節郎
- Organizer
  第12回運動器科学研究会
- Place of Presentation
  高知県安芸郡
- Data Source
  KAKENHI-PROJECT-23592222
[Presentation] 軟骨細胞肥大分化過程における SnoNの機能解析と変形性関節症との関連2011
- Author(s)
  河村　一郎,　石堂　康弘,　今村　勝行, 横内　雅博,　小宮　節郎, 　前田　真吾
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋市
- Data Source
  KAKENHI-PROJECT-23592221
[Presentation] 骨肉腫におけるGOLPH3遺伝子の高発現とその機能解析2010
- Author(s)
  救仁郷修, 瀬戸口啓夫, 松野下幸弘, 佐々木裕美, 永尾宗子, 小宮節郎
- Organizer
  第43回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] Functional analysis of over-expressed GOLPH3 in osteosarcoma and rabdomyo sarcoma.2010
- Author(s)
  救仁郷修, 瀬戸口啓夫, 松野下幸弘, 佐々木裕美, 小宮節郎
- Organizer
  The 20th Japanese-Korean Combined Or thopaedic Symposium
- Place of Presentation
  Kagoshima, Japan
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] 骨肉腫における切断術症例の検討2010
- Author(s)
  永野聡、横内雅博、寺原幹雄、中島隆之、善明美千久、有島善也、小宮節郎
- Organizer
  第43回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  新宿区、東京都
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] 骨肉腫におけるHEY1 発現上昇とHEY1の機能解析2010
- Author(s)
  松野下幸弘, 瀬戸口啓夫, 佐々木裕美, 永尾宗子, 救仁郷修, 小宮節郎
- Organizer
  第43回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] Functional analysis of EGR1 and its up-regulation using anti-tumour agents.2010
- Author(s)
  松野下幸弘, 瀬戸口啓夫, 救仁郷修, 廣津匡隆, 小宮節郎
- Organizer
  55th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  New Orleans, USA
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] 三次元細胞培養を用いた腫瘍内遺伝子治療ベクター感染効率の解析2010
- Author(s)
  永野聡、Boucher Y、小宮節郎
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市、京都府
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] Functional analysis of EGR1 and its up-regulation using anti-tumour agents.2010
- Author(s)
  Matsunoshita Y, Setoguchi T, Sasaki H, Kunigou O, Hirotsu M, Nagano S, Komiya S
- Organizer
  7th Combined Meeting of the Orthopaed ic Research Societies
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] Knock down of overexpressed smoothened prevent osteosarcoma growth and invasion.2010
- Author(s)
  Sasaki H, Setoguchi T, Hirotusu H, Matsunoshita Y, Kunigou O, Komiya S.
- Organizer
  The 20th Japanese-Korean Combined Or thopaedic Symposium
- Place of Presentation
  Kagoshima, Japan
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] 骨肉腫におけるSMOの機能抑制による増殖能・浸潤能抑制効果とそのメカニズムの解析2010
- Author(s)
  廣津匡隆, 瀬戸口啓夫, 佐々木裕美, 松野下幸弘, 永尾宗子, 救仁郷修, 小宮節郎
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] 骨肉腫を多因子で特異標的かつ効果的に治療する革新的な増殖制御型アデノウイルス薬の開発2010
- Author(s)
  堀川良治、永野聡、神囿純一、池田美奈子、小宮節郎、小戝健一郎
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市、京都府
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] Functional analysis of EGR1 and its up-regulation using anti-tumour agents.2010
- Author(s)
  Matsunoshita Y, Setoguchi T, Sasaki H, Kunigou O, Hirotsu H, Nagano S, Komiya S
- Organizer
  The 20th Japanese-Korean Combined Or thopaedic Symposium
- Place of Presentation
  Kagoshima, Japan
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] Inhibition of Hedgehog pathway prevents rhabdomyosarcoma growth.2010
- Author(s)
  Kawabata N, Setoguchi T, Komiya S
- Organizer
  第32回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] Functional analysis of EGR1 and its up-regulation using anti-tumor agents2010
- Author(s)
  Matsunoshita Y., Setoguchi T., Kunigou O., Hirotsu M., Komiya S.
- Organizer
  56th Annual Meeting of Orthopedic Research Society
- Place of Presentation
  New Orleans, USA
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] Tumor cell death-inducing Pretreatments Improves Distribution and Efficacy of Oncolytic Virus in Solid tumors2010
- Author(s)
  Nagano S, Komiya S, Boucher Y.
- Organizer
  The 20th Japanese-Korean Combined Orthopaedic Symposium
- Place of Presentation
  指宿市、鹿児島県
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] ヒト骨肉種におけるGLI2の強発現とGLI2をターゲットにした骨肉腫治療の可能性2010
- Author(s)
  永尾宗子, 瀬戸口啓夫, 廣津匡隆, 佐々木裕美, 松野下幸弘, 救仁郷修, 小宮節郎
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] 骨肉腫におけるSMOの機能制御による転移能抑制効果とそのメカニズムの解析2010
- Author(s)
  佐々木裕美, 瀬戸口啓夫, 廣津匡隆, 松野下幸弘, 救仁郷修, 永尾宗子, 小宮節郎
- Organizer
  第43 回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] 固形腫瘍の細胞密度と細胞外マトリックスの制御による新しいoncolytic遺伝子治療2009
- Author(s)
  永野聡、Boucher Y、小宮節
- Organizer
  第42回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  横浜市
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] Functional analysis of EGR1 and its up-regulation using anti-tumor agents.2009
- Author(s)
  松野下幸弘, 瀬戸口啓夫, 救仁郷修, 廣津匡隆, 小宮節郎
- Organizer
  The 19th Korean-Japanese Combined Or thopaedic Symposium
- Place of Presentation
  Gwangju, Korea
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] Improved distribution and efficacy of oncolytic virus in solid tumors by apoptosis-inducing pretreatments2009
- Author(s)
  Nagano S., Komiya S., Boucher Y.
- Organizer
  15 th meeting of European CanCer Organisation(ECCO)
- Place of Presentation
  Berlin, Germany
- Year and Date
  2009-09-21
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] Inhibition of Notch pathway prevents osteosarcoma growth by regulation of cell cycle2009
- Author(s)
  Setoguchi T., Tanaka M., Komiya S.
- Organizer
  15 th meeting of European CanCer Organisation(ECCO)
- Place of Presentation
  Berlin, Germany
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] ヒト骨肉種におけるGLI2の強発現とGLI2をターゲットにした骨肉腫治療2009
- Author(s)
  廣津匡隆, 瀬戸口啓夫, 松野下幸弘, 小宮節郎
- Organizer
  第42回日本整形外科学会基礎骨・軟部腫瘍学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] アポトーシス誘導型の前治療はoncolytic virusの腫瘍内拡散と抗腫瘍効果を向上させる2009
- Author(s)
  永野聡、小宮節郎、Boucher Y.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21591920
[Presentation] Inhibition of Notch pathway prevents osteosarcoma growth in vitro and in vivo by cell cycle regulation.2009
- Author(s)
  Setoguchi T, Tanaka M, Hirotsu H, Sasaki H, Komiya S
- Organizer
  The joint 15th Congress of the European Cancer Organization and 34th Congress of the European Society for Medical Oncology
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] SMOの機能制御による骨肉腫増殖抑制効果とSMO inhibitorの臨床応用の可能性2009
- Author(s)
  廣津匡隆, 瀬戸口啓夫, 松野下幸弘, 佐々木裕美, 小宮節郎
- Organizer
  第42回日本整形外科学会基礎骨・軟部腫瘍学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] (シンポディウム)Notchシグナルを標的とした骨肉腫に対する治療2008
- Author(s)
  瀬戸口啓夫、田中源幸、廣津匡隆、佐々木裕美、小宮節郎
- Organizer
  第41回日本整形外科骨・軟部腫瘍学術集会
- Place of Presentation
  京都交際会館
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] 骨・軟部腫瘍におけるがん幹細胞の研究2008
- Author(s)
  瀬戸口啓夫, 小宮節郎, 他
- Organizer
  第23回日本整形外科学会基礎学術集会シンポディウム
- Place of Presentation
  京都国際会議場(京都市)
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-18390419
[Presentation] Notch pathway is activated in osteosarcoma and inhibition of γ-secretase inhibit osteosarcoma growth by cell cycle regulation2008
- Author(s)
  Tanaka M. Setoguchi T. Hirotsu M. Sasaki H. Komiya S.
- Organizer
  The 30st Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  モントリオールカナダ
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] Inhibition of Notch pathway prevent s osteosarcoma growth in vitro and in vivo by cell cycle regulation.2008
- Author(s)
  Setoguchi T, Tanaka M, Hirotsu H, Sasaki H, Komiya S
- Organizer
  The 18th Japanese-Korean Combined Or thopaedic Symposium.
- Place of Presentation
  Nagasaki, Japan
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] Conditionally replicating adenovirus regulated with 4 independent caneer-specific factors enhances cancer-specificity without reducing potentanti-cancer effect ; the importance of EIB promoter.2008
- Author(s)
  Murofushi Y, Nagano S, Komiya S, Kosai K.
- Organizer
  The American Society of Gene Therapy's 11th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] Notch pathway is activated in osteos arcoma and inhibitors of.-secretase inhibit osteosarcoma growth by cell cycle regulation.2008
- Author(s)
  Tanaka M, Setoguchi T, Hirotsu M, Sasaki H, Komiya S
- Organizer
  ASBMR 30th Annual Meeting Montreal
- Place of Presentation
  Quebec, Canada
- Data Source
  KAKENHI-PROJECT-20591786
[Presentation] New investigator recognition award 受賞 Notch pathway is activated in osteosarcoma and inhibitors of γ-secretase prevents osteosarcoma growth by cell cycle regulation2008
- Author(s)
  Takao Setoguchi, Motoyuki Tanaka, Masataka Hirotsu, Hiromi Sasaki, Setsuro Komiya
- Organizer
  Annual meeting of Orthopaedic research Society
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] Notch Pathway is Activated in Osteosarcoma and Inhibitors of γ-secretase Prevents Osteosarcoma Growth by Cell Cycle Regulation2008
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  54th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Francisco, California U.S.A.
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] 骨・軟部腫瘍におけるがん幹細胞の研究2008
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-18390419
[Presentation] 悪性骨・軟部腫瘍におけるNotch の発現とその意義2007
- Author(s)
  Setoguchi T., Tanaka M., Komiya S.
- Organizer
  第40回日本整形外科骨・軟部腫瘍学術集会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] Conditionally Replicating Adenovirus Regulated by Survivin and CEA Promoters Exerted More Strict Cancer Specificity and Potent Anti-Cancer Effect.2007
- Author(s)
  Yoshiteru Murofushi, Junichi Kamizono, Ngin Cin Khai, Tomoyuki Takahashi, Setsuro Komiya, Ken-ichiro Kosai.
- Organizer
  第13回日本遺伝子治療学会
- Place of Presentation
  名古屋市(愛知がんセンター)
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] 骨肉種におけるNotch の発現と機能v2007
- Author(s)
  瀬戸口啓夫、田中源幸、廣津匡隆、佐々木裕美、小宮節郎
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] In vivo Inhibition of Osteosarcoma Growth by Notch Pathway Inhibition2007
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  The 29th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Honolulu, Hawaii U.S.A.
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] In vivo Inhibition of Osteosarcoma Growth by Notch Pathway Inhibition2007
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  第66回癌学会学術総会
- Place of Presentation
  横浜パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] 整形外科悪性腫瘍におけるNotchの発現とその意義2007
- Author(s)
  田中源幸、瀬戸口啓夫、小宮節郎
- Organizer
  第112回西日本整形・災害外科学会
- Place of Presentation
  日米子
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] 骨肉腫におけるNotch の発現とその機能2007
- Author(s)
  田中源幸、瀬戸口啓夫、小宮節郎
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] Gamma secreatse inhibitor blocks Notch activation and prevented osteosarcoma cells proliferation in vitro and in vivo2007
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  Combined Meeting of the Orthopaedic Research Society
- Place of Presentation
  Honolulu, Hawaii U.S.A.
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] 骨肉腫におけるNotchの発現と機能2007
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  第30回日本分子生物学会大会
- Place of Presentation
  横浜パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] 骨軟部悪性腫瘍細胞株におけるがん幹細胞様細胞の研究2007
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  静岡県浜松市
- Data Source
  KAKENHI-PROJECT-18390419
[Presentation] Survivin-Responsive Conditionally Replicating Adenovirus Additionally Regulated with Cancer Specificity without Reducing Anti-Cabcer Effect.2007
- Author(s)
  Yoshiteru Murofushi, Junichi Kamizono, Ngin Cin Khai, Tomoyuki Takahashi, Setsuro Komiya, Ken-ichiro Kosai.
- Organizer
  The 10th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Seattle, Washington, USA
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19390286
[Presentation] In vivo inhibition of osteosarcoma growth by Notch pathway inhibition2007
- Author(s)
  Setoguchi T. Tanaka M. Hirotsu M. Sasaki H. Komiya S.
- Organizer
  6^<th> Combined Meeting of the Orthopaedic Research Society
- Place of Presentation
  ホノルルハワイ
- Data Source
  KAKENHI-PROJECT-19591725
[Presentation] Myc Target 1 (MYCT1) Gene is a Novel Target of TGF-β Signaling to Promote Differentiation of Chondrosarcoma Cells
- Author(s)
  Yahiro, Y; Maeda, S; Shinohara, N; Matsuyama, K; Kawamura, I; Setoguchi, T; Nagano, S; Yokouchi, M; Ishidou, Y; Komiya, S
- Organizer
  Orthopedic Research Society 2015 Annual Meeting
- Place of Presentation
  アメリカ合衆国、ラスベガス (MGM Grand Hotel)
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-26462307
[Presentation] 骨・軟部肉腫に対する分子標的治療研究
- Author(s)
  瀬戸口啓夫、小宮節郎
- Organizer
  第87回日本整形外科学会学術総会
- Place of Presentation
  神戸市、神戸国際会議場
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] GLI転写を抑制する三酸化ヒ素と抗がん剤併用による骨肉腫増殖抑制効果
- Author(s)
  永田政仁，瀬戸口啓夫，北本宗子，棈松昌彦，永野　聡，中村俊介，北本宗子，横内雅博，石堂康弘，小宮節郎
- Organizer
  第47回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  大阪市、大阪国際会議場
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] 革新的癌治療薬を目指した増殖制御型アデノウイルスの独自開発から医師主導治験へ
- Author(s)
  永野　聡，小戝健一郎，小宮節郎
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島市、城山観光ホテル
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] GLI2によるRPS3発現を介した骨肉腫転移解析と臨床薬剤による阻害
- Author(s)
  永田政仁，永野　聡，中村俊介，北本宗子，棈松昌彦，横内雅博，石堂康弘，小宮節郎，瀬戸口啓夫
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島市、城山観光ホテル
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] GLI2とSMO制御による骨肉腫転移能抑制の相乗効果解析
- Author(s)
  永田政仁，鶴亜里紗，小宮節郎，瀬戸口啓夫
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市、パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592237
[Presentation] Examination of a New MRI Severity Scoring System and Postoperative Results in Patients with Cervical Spinal Tumors
- Author(s)
  Masahiko Abematsu, Hiroyuki Tominaga, Fumito Tanabe, Hiroki Tawaratsumida, Takuya Yamamoto, Kazunori Yone、Setsuro Komiya
- Organizer
  CSRS AP 5 Viet Nam 2014
- Place of Presentation
  Viet Nam
- Year and Date
  2014-04-03 – 2014-04-08
- Data Source
  KAKENHI-PROJECT-24592203
[Presentation] GLI2阻害による骨肉腫増殖・転移抑制メカニズム解析
- Author(s)
  瀬戸口啓夫，永尾宗子，中村俊介，永野　聡，横内雅博，棈松昌彦，石堂康弘，小宮節郎
- Organizer
  第87回日本整形外科学会学術総会
- Place of Presentation
  神戸市、神戸国際会議場
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-24592237

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KOMIYA Setsurou 小宮 節郎

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Long-term survival of total joint arthroplasty by drug inhibition of autophagyPrincipal Investigator

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KOMIYA Setsurou 小宮節郎