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SUGAWARA Fumio  菅原 二三男

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… Alternative Names

菅原 二三男  スガワラ フミオ

FUMIO SUGAWARA  菅原 二三男

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Researcher Number 30192123
Other IDs
Affiliation (based on the past Project Information) *help 2017: 東京理科大学, 理工学部, 教授
2015: 東京理科大学, 理工学部, 教授
2011: 東京理科大学, 理工学部, 教授
2004 – 2009: 東京理科大学, 理工学部, 教授
2003: 東京理科大学, 教授 … More
2000 – 2001: 東京理科大学, 理工学部, 教授
1998: SCIENCE UNIVERSITY OF TOKYO,DEPARTMENT OF APPLIED BIOLOGICAL SCIENCE,ASSOCIATE PROFESSOR, 理工学部, 助教授
1997: 理科大, 理工学部, 助教授
1992: 理化学研究所, 薬剤作用研究室, 副主任研究員
1989: 理化学研究所, 薬剤作用研究室, 研究員 Less
Review Section/Research Field
Principal Investigator
Living organism molecular science / 製造化学・食品 / Bioorganic chemistry / Bioproduction chemistry/Bioorganic chemistry / Chemical pharmacy / Bioproduction chemistry/Bioorganic chemistry
Except Principal Investigator
Biomolecular chemistry / Breeding science
Keywords
Principal Investigator
QCM / ファージディスプレイ / SPR / 結合タンパク質 / 受容体 / カンプトテシン / ファージディスプレイ法 / エボラ出血熱ウイルス / 日本脳炎ウイルス / インフルエンザウイルス … More / 抗ウイルス薬 / receptor / binding protein / phage display / etoposide / camptothecin / anti-cancer drug / E2F / EP1 / オーファン受容体 / クオーツマイクロバランス振動法 / 表面プラズモン共鳴 / G-タンパク質 / プロスタグランディン / 抗癌剤 / FKBP / 医薬 / エトポシド / 抗腫瘍薬 / DNA replication / dehydroaltenusin / phytotoxin / DNA polvmerase beta and lambda / sanapyrone A / HIV-1RT / ヒト免疫不全症候群ウィルス / ネルボン酸 / lithochol酸 / solanapyrone / NMR / phage display法 / DNAポリメラーゼβ / SQDG / SQMG / DNAポリメラーゼ / snti-tumour / DNA polymerase / sulfonoquinovoayl-diacylglyceride / DNApolymerase / Sulfonosquinovose / DNA polymerace / allylglucoside / Sulfonoquinovose / 遺伝子変異株 / バイオインフォマティクス / 医薬結合タンパク質 / 標的分子 / 結合アミノ酸配列 / ゲノム / 遺伝子変異体 / EGFR / IGF-1R / イレッサ / ZD1839 / 出芽組織ライブラリ / 培養細胞ライブラリ / イネ(Orza sativa) / nodulin / Ipha-exansin2 / ジベレリン結合タンパク / ジベレリン / トウモロコシ根部屈曲試験 / 緑豆上胚軸の伸長試験 / 酸性フォフファターゼ / α-アミラーゼ / アミノ酸 / Aspergillus niger / マルホルミン / X線結晶解析 / 植物病原菌 / 植物制御活性物質 / セスキテルペン / エレモフィラン … More
Except Principal Investigator
ケミカルバイオロジー / 標的タンパク質 / ファージディスプレイ / 神経細胞死 / 活性窒素 / 神経保護効果 / 生理活性物質 / 天然物 / 植物 / 遺伝子 / 育種学 / RNA-Seq / 環状ペプチド / BACクローン / ホソヘリカメムシ / アズキゾウムシ / 貯蔵害虫 / 抵抗性 / ゲノム Less
  • Research Projects

    (10 results)
  • Research Products

    (384 results)
  • Co-Researchers

    (8 People)
  •  抗ウイルス抗体を産生する新規抗ウイルス剤EdAPの研究Principal Investigator

    • Principal Investigator
      菅原 二三男
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Tokyo University of Science
  •  Target identification and mechanism of action of neoechinulin A

    • Principal Investigator
      KAMISUKI Shinji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Azabu University
  •  Elucidation of molecular basis of insect resistance in mungbean using comparative genomics information

    • Principal Investigator
      ISHIMOTO Masao
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Breeding science
    • Research Institution
      National Institute of Agrobiological Sciences
      National Agricultural Research Organization
  •  The new method to identify small molecules binding proteins by usingmutants and genome sequencesPrincipal Investigator

    • Principal Investigator
      菅原 二三男
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      Tokyo University of Science
  •  Identifications of small molecule drug-binding proteins by using the affinitiesPrincipal Investigator

    • Principal Investigator
      SUGAWARA Fumio
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Tokyo University of Science
  •  ディスプレイクローニングと計算科学による結合タンパク質の戦略的決定Principal Investigator

    • Principal Investigator
      菅原 二三男
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Living organism molecular science
    • Research Institution
      Tokyo University of Science
  •  STUDY OF BIOPROBE FOR DNA POLYMERASESPrincipal Investigator

    • Principal Investigator
      FUMIO SUGAWARA
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      TOKYO UNIVERSITY OF SCIENCE
  •  SYNTHETIC STUDY ON BIOLOGICAL ACITIVE CARBOHYDRATESPrincipal Investigator

    • Principal Investigator
      SUGAWARA Fumio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      SCIENCE UNIVERSITY OF TOKYO
  •  植物病原性物質マルホルミン類の作用機構Principal Investigator

    • Principal Investigator
      菅原 二三男
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      製造化学・食品
    • Research Institution
      The Institute of Physical and Chemical Research
  •  雑草を宿主とする植物病菌のより生産される新植物制御活性物資に関する研究Principal Investigator

    • Principal Investigator
      菅原 二三男
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      製造化学・食品
    • Research Institution
      The Institute of Physical and Chemical Research

All 2018 2016 2015 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] Handbook of Nutritional Biochemistry : Genomics2009

    • Author(s)
      Yoshiyuki Mizushina,, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida
    • Total Pages
      538
    • Publisher
      INHIBITORY MECHANISM OF LONGER CHAIN FATTY ACIDS ON MAMMALIAN DNA POLYMERASE B ACTIVITY
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Book] クラーク 分子生物学2008

    • Author(s)
      田沼精一, 菅原二三男, 他
    • Total Pages
      860
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Book] クラーク分子生物学2008

    • Author(s)
      田沼精一,菅原二三男, 他
    • Total Pages
      860
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Book] 生物有機化学 基礎化学編2007

    • Author(s)
      菅原 二三男 監訳
    • Total Pages
      400
    • Publisher
      丸善
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Book] 生物有機化学 生化学編2007

    • Author(s)
      菅原 二三男 監訳
    • Total Pages
      400
    • Publisher
      丸善
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Book] 生物有機化学 : 生化学編2007

    • Author(s)
      菅原二三男
    • Total Pages
      402
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Book] 生物有機化学 : 基礎化学編2007

    • Author(s)
      菅原二三男
    • Total Pages
      405
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Book] 生物有機化学 : 有機化学編2007

    • Author(s)
      菅原二三男
    • Total Pages
      240
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Book] 生物有機化学 有機化学編2007

    • Author(s)
      菅原 二三男 監訳
    • Total Pages
      200
    • Publisher
      丸善
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of proteins that bind to the neuroprotective agent neoechinulin A2018

    • Author(s)
      Kamisuki Shinji、Himeno Natsumi、Tsurukawa Yukine、Kusayanagi Tomoe、Takeno Masahiro、Kamakura Takashi、Kuramochi Kouji、Sugawara Fumio
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 82 Issue: 3 Pages: 442-448

    • DOI

      10.1080/09168451.2018.1433018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K01808
  • [Journal Article] Neoechinulin A induced memory improvements and antidepressant-like effects in mice2016

    • Author(s)
      Sachie Sasaki-Hamada, Maho Hoshi, Yuki Niwa, Yudai Ueda, Aya Kokaji, Shinji Kamisuki, Kouji Kuramochi, Fumio Sugawara, Jun-Ichiro Oka
    • Journal Title

      Progress in Neuro-Psychopharmacology & Biological Psychiatry

      Volume: 71 Pages: 155-161

    • DOI

      10.1016/j.pnpbp.2016.08.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K01808
  • [Journal Article] Anti-hepatitis C Virus Natural Product from a Fungus, Penicillium herquei2016

    • Author(s)
      Nishikori S, Takemoto K, Kamisuki S, Nakajima S, Kuramochi K, Tsukuda S, Iwamoto M, Katayama Y, Suzuki T, Kobayashi S, Watashi K, Sugawara F
    • Journal Title

      J Nat Prod

      Volume: 79 Issue: 2 Pages: 442-446

    • DOI

      10.1021/acs.jnatprod.5b00555

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-15K07419
  • [Journal Article] Low doses of the mycotoxin citrinin protect cortical neurons against glutamate-induced excitotoxicity2016

    • Author(s)
      Nakajima Y, Iguchi H, Kamisuki S, Sugawara F, Furuichi T and Shinoda Y
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 41 Issue: 2 Pages: 311-319

    • DOI

      10.2131/jts.41.311

    • NAID

      130005132670

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08192, KAKENHI-PROJECT-15K14356, KAKENHI-PROJECT-15K07419, KAKENHI-PROJECT-26290026
  • [Journal Article] Ridaifen G, tamoxifen analog, is a potent anticancer drug working through a combinatorial association with multiple cellular factors.2015

    • Author(s)
      Ikeda K, Kamisuki S, Uetake S, Mizusawa A, Ota N, Sasaki T, Tsukuda S, Kusayanagi T, Takakusagi Y, Morohashi K, Yamori T, Dan S, Shiina I, Sugawara F.
    • Journal Title

      Bioorg Med Chem.

      Volume: 23 Issue: 18 Pages: 6118-6124

    • DOI

      10.1016/j.bmc.2015.08.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07419
  • [Journal Article] Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.2015

    • Author(s)
      Izaguirre-Carbonell, J., Kawakubo, H., Murata, H., Tanabe, A., Takeuchi, T., Kusayanagi, T., Tsukuda, S., Hirakawa, T., Iwabata, K., Kanai, Y., Ohta, K., Miura, M., Sakaguchi, K., Matsunaga, S., Sahara, H., Kamisuki, S., and Sugawara, F.
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 15136-15136

    • DOI

      10.1038/srep15136

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05962, KAKENHI-PROJECT-15K07419, KAKENHI-PROJECT-26291067
  • [Journal Article] Isolation and structure of vanitaracin A, a novel anti-hepatitis B virus compound from Talaromyces sp2015

    • Author(s)
      Matsunaga H, Kamisuki S, Kaneko M, Yamaguchi Y, Takeuchi T, Watashi K, Sugawara F
    • Journal Title

      Bioorg Med Chem Lett

      Volume: 25 Issue: 19 Pages: 4325-4328

    • DOI

      10.1016/j.bmcl.2015.07.067

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460565, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15K07419
  • [Journal Article] Inhibition of hypoxia-inducible factor via upregulation of von Hippel-Lindau protein induces "angiogenic switch off" in a hepatoma mouse model.2015

    • Author(s)
      Iwamoto H, Nakamura T, Koga H, Izaguirre-Carbonell J, Kamisuki S, Sugawara F, Abe M, Iwabata K, Ikezono Y, Sakaue T, Masuda A, Yano H, Ohta K, Nakano M, Shimose S, Shirono T, Torimura T.
    • Journal Title

      Molecular Therapy Oncolytics

      Volume: 2 Pages: 15020-15020

    • DOI

      10.1038/mto.2015.20

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-15K07419, KAKENHI-PROJECT-25461018
  • [Journal Article] A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide2015

    • Author(s)
      Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T
    • Journal Title

      J Virol

      Volume: 89 Issue: 23 Pages: 11945-11953

    • DOI

      10.1128/jvi.01855-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460565, KAKENHI-ORGANIZER-24115001, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-15J03185, KAKENHI-PROJECT-15K07419, KAKENHI-PROJECT-25291016
  • [Journal Article] Enhancement of Cellulose Degradation by Cattle Saliva.2015

    • Author(s)
      Seki Y, Kikuchi Y, Kimura Y, Yoshimoto R, Takahashi M, Aburai K, Kanai Y, Ruike T, Iwabata K, Sugawara F, Sakai H, Abe M, Sakaguchi K.
    • Journal Title

      PLoS One.

      Volume: 10 Issue: 9 Pages: e0138902-e0138902

    • DOI

      10.1371/journal.pone.0138902

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07419
  • [Journal Article] Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulate its activity2015

    • Author(s)
      J Izaguirre-Carbonell 1, H Kawakubo 1, H Murata 1, K Ohta 1, T Kusayanagi 1, S Tsukuda 1, T Hirakawa 1, K Iwabata 1, Y Kanai 1, S Matsunaga 1, S Kamisuki 1, K Sakaguchi 1, F Sugawara 1
    • Journal Title

      Planta Med

      Volume: 2015 Issue: 11 Pages: 81-81

    • DOI

      10.1055/s-0035-1556282

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07419
  • [Journal Article] A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol(betaSQDG)binds to Met1-Arg95 region of murine DNA polymerase lambda(Mmpol lambda)and inhibits its nuclear transit2010

    • Author(s)
      Takakusagi K, Takakusagi Y, Ohta K, Aoki S, Sugawara F, Sakaguchi K.
    • Journal Title

      Protein Eng Des Sel 23

      Pages: 51-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit.2010

    • Author(s)
      Takakusagi K, Takakusagi Y, Ohta K, Aoki S, Sugawara F, Sakaguchi K.
    • Journal Title

      Protein Eng Des Sel 23(2)

      Pages: 51-60

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of trimannoside-recognizing peptide sequences from a T7 phage display screen using a QCM device.2009

    • Author(s)
      Nishiyama K, Takakusagi Y, Kusayanagi T, Matsumoto Y, Habu S, Kuramochi K, Sugawara F, Sakaguchi K, Takahashi H, Natsugari H, Kobayashi S.
    • Journal Title

      Bioorg Med Chem 17(1)

      Pages: 195-202

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth.2009

    • Author(s)
      Matsui Y, Hada T, Maeda N, Sato Y, Yamaguchi Y, Takeuchi T, Takemura M, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.
    • Journal Title

      Cancer Lett 283(1)

      Pages: 101-7

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors.2009

    • Author(s)
      Kuramochi K, Fukudome K, Kuriyama I, Takeuchi T, Sato Y, Kamisuki S, Tsubaki K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem 17(20)

      Pages: 7227-38

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Synthesis and structure-activity relationships of dehydroalt enusin derivatives as selective DNA polymerase alpha inhibitors2009

    • Author(s)
      Kuramochi K, Fukudome K, Kuriyama I, Takeuchi T, Sato Y, Kamisuki S, Tsubaki K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. 15

      Pages: 7227-7238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] 3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain2009

    • Author(s)
      Mizushina Y, Motoshima H, Yamaguchi Y, Takeuchi T, Hirano K, Sugawara F, Yoshida H.
    • Journal Title

      Mar Drugs. 7

      Pages: 624-639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.2009

    • Author(s)
      Kimura T, Takeuchi T, Kumamoto-Yonezawa Y, Ohashi E, Ohmori H, Masutani C, Hanaoka F, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. 1

      Pages: 1811-1816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] 3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain.2009

    • Author(s)
      Mizushina Y, Motoshima H, Yamaguchi Y, Takeuchi T, Hirano K, Sugawara F, Yoshida H.
    • Journal Title

      Mar Drugs 7(4)

      Pages: 624-39

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Antitumor antibiotic fostriecin covalently binds to cysteine-269 residue of protein phosphatase 2A catalytic subunit in mammalian cells.2009

    • Author(s)
      Takeuchi T, Takahashi N, Ishi K, Kusayanagi T, Kuramochi K, Sugawara F.
    • Journal Title

      Bioorg Med Chem 17(23),17(23)

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Chlorogenic acid facilitates root hair formation in lettuce seedlings.2009

    • Author(s)
      Narukawa M, Kanbara K, Tominaga Y, Aitani Y, Fukuda K, Kodama T, Murayama N, Nara Y, Arai T, Konno M, Kamisuki S, Sugawara F, Iwai M, Inoue Y.
    • Journal Title

      Plant Cell Physiol 50(3)

      Pages: 504-14

    • NAID

      10027338353

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.2009

    • Author(s)
      Kimura T, Takeuchi T, Kumamoto-Yonezawa Y, Ohashi E, Ohmori H, Masutani C, Hanaoka F, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem 17(5)

      Pages: 1811-6

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of trimannoside-recognizing peptide sequences from a T7 phage display screen using a QCM device.2009

    • Author(s)
      Nishiyama K, Takakusagi Y, Kusayanagi T, Matsumoto Y, Habu S, Kuramochi K, Sugawara F, Sakaguchi K, Takahashi H, Natsugari H, Kobayashi S.
    • Journal Title

      Bioorg Med Chem. 17

      Pages: 195-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Validation of small-molecule/protein interactions by the T7 phage display strategy using a quartz-crystal microbalance device2009

    • Author(s)
      Takakusagi Y, Takakusagi K, Sugawara F, Sakaguchi K.
    • Journal Title

      タンパク質核酸酵素 54

      Pages: 1203-1209

    • NAID

      40016708059

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Antitumor antibiotic fostriecin covalently binds to cysteine-269 residue of protein phosphatase 2A catalytic subunit in mammalian cells2009

    • Author(s)
      Takeuchi T, Takahashi N, Ishi K, Kusayanagi T, Kuramochi K, Sugawara F.
    • Journal Title

      Bioorg Med Chem. 17

      Pages: 8113-8122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Chlorogenic acid facilitates root hair formation in lettuce seedlings2009

    • Author(s)
      Narukawa M, Kanbara K, Tominaga Y, Aitani Y, Fukuda K, Kodama T, Murayama N, Nara Y, Arai T, Konno M, Kamisuki S, Sugawara F, Iwai M, Inoue Y.
    • Journal Title

      Plant Cell Physiol. 50

      Pages: 504-514

    • NAID

      10027338353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Chlorogenic acid facilitates root hair formation in lettuce seedlings.2009

    • Author(s)
      Narukawa M, Kanbara K, Tominaga Y, Aitani Y, Fukuda K, Kodama T, Murayama N, Nara Y, Arai T, Konno M, Kamisuki S, Sugawara F, Iwai M, Inoue Y.
    • Journal Title

      Plant Cell Physiol. 50

      Pages: 504-514

    • NAID

      10027338353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases2009

    • Author(s)
      Kimura T, Takeuchi T, Kumamoto-Yonezawa Y, Ohashi E, Ohmori H, Masutani C, Hanaoka F, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. 17

      Pages: 1811-1816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Structure and activity relationship of monogalactosyl diacyl glycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth2009

    • Author(s)
      Matsui Y, Hada T, Maeda N, Sato Y, Yamaguchi Y, Takeuchi T, Takemura M, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.
    • Journal Title

      Cancer Lett. 283

      Pages: 101-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool2008

    • Author(s)
      Takakusagi Y, Kuramochi K, Takagi M, Kusayanagi T, Manita D, Ozawa H, Iwakiri K, Takakusagi K, Miyano Y, Nakazaki A, Kobayashi S, Sugawara F, Sakaguchi K
    • Journal Title

      Bioorg Med Chem. 16

      Pages: 9837-9846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta.2008

    • Author(s)
      Mizushina Y, Manita D, Takeuchi T, Sugawara F, Kumamoto-Yonezawa Y, Matsui Y, Takemura M, Sasaki M, Yoshida H, Takikawa H.
    • Journal Title

      Molecules 14(1)

      Pages: 102-21

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Coenzyme Q(10) as a potent compound that inhibits Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Takakusagi Y, Yonezawa Y, Mizuno T, Yanagi K, Imamoto N, Sugawara F, Sakaguchi K, Yoshida H, Fujita M.
    • Journal Title

      Biochim Biophys Acta 1780(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] The inhibitory action of SQDG (sulfoquinovosyl diacylglycerol) from spinach on Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Hada T, Maeda N, Sugawara F, Yoshida H, Fujita M.
    • Journal Title

      Biochimie 90(6)

      Pages: 947-56

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool.2008

    • Author(s)
      Takakusagi Y, Kuramochi K, Takagi M, Kusayanagi T, Manita D, Ozawa H, Iwakiri K, Takakusagi K, Miyano Y, Nakazaki A, Kobayashi S, Sugawara F, Sakaguchi K.
    • Journal Title

      Bioorg Med Chem 16(22)

      Pages: 9837-46

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Synthesis and biological activities of neoechinulin A derivatives: new aspects of structure-activity relationships for neoechinulin A.2008

    • Author(s)
      Kuramochi K, Ohnishi K, Fujieda S, Nakajima M, Saitoh Y, Watanabe N, Takeuchi T, Nakazaki A, Sugawara F, Arai T, Kobayashi S.
    • Journal Title

      Chem Pharm Bull 56(12)

      Pages: 1738-43

    • NAID

      110007004710

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells.2008

    • Author(s)
      Kuriyama I, Mizuno T, Fukudome K, Kuramochi K, Tsubaki K, Usui T, Imamoto N, Sakaguchi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Molecules 13(12)

      Pages: 2948-61

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Synthesis and biological activities of neoechinulin A derivatives : new aspects of structure-activity relationships for neoechinulin A2008

    • Author(s)
      Kuramochi K, Ohnishi K, Fujieda S, Nakajima M, Saitoh Y, Watanabe N, Takeuchi T, Nakazaki A, Sugawara F, Arai T, Kobayashi S.
    • Journal Title

      Chem Pharm Bull(Tokyo). 56

      Pages: 1738-1743

    • NAID

      110007004710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Novel azaphilones, kasanosins A and B, which are specific in hibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp.2008

    • Author(s)
      Kimura T, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. Feb 15(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Syntheses and applications of fluorescent and biotinylated epolactaene derivatives: Epolactaene and its derivative induce disulfide formation.2008

    • Author(s)
      Kuramochi K, Yukizawa S, Ikeda S, Sunoki T, Arai S, Matsui R, Morita A, Mizushina Y, Sakaguchi K, Sugawara F, Ikekita M, Kobayashi S.
    • Journal Title

      Bioorg Med Chem 16(9)

      Pages: 5039-49

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Downregulation of Tie2 gene by a novel antitumor sulfolipid, 3'-sulfoquinovosyl-1'-monoacylglycerol, targeting angiogenesis.2008

    • Author(s)
      Mori Y, Sahara H, Matsumoto K, Takahashi N, Yamazaki T, Ohta K, Aoki S, MiuraM, Sugawara F, SakaguchiK, Sato N.
    • Journal Title

      Cancer Sci. 99

      Pages: 1063-1970

    • NAID

      10024006631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Coenzyme Q(10) as a potent compound that inhibits Cdtl-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Takakusagi Y, Yonezawa Y, Mizuno T, Yanagi K, Imamoto N, Sugawara F, Sakaguchi K, Yoshida H, Fujita M.
    • Journal Title

      Biochim Biophys Acta. 1780

      Pages: 203-213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha.2008

    • Author(s)
      Kuriyama I, Fukudome K, Kamisuki S, Kuramochi K, Tsubaki K, Sakaguchi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Int J Mol Med. 22

      Pages: 793-799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp.2008

    • Author(s)
      Nishida M, Ida N, Horio M, Takeuchi T, Kamisuki S, Murata H, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      v Bioorg Med Chem. 16

      Pages: 5115-5122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] A facile method to screen inhibitors of protein-protein interactions including MDM2-p53 displayed on T7 phage.2008

    • Author(s)
      Ishi K, Sugawara F.
    • Journal Title

      Biochem Pharmacol. 75

      Pages: 1743-1750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of a methotrexate-binding peptide from a T7 phage display screen using a QCM device.2008

    • Author(s)
      Takakusagi Y, Kuroiwa Y, Sugawara F, Sakaguchi K
    • Journal Title

      Bioorg Med Chem. 52

      Pages: 556-562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] A facile method to screen inhibitors of protein-protein interactions including MDM2-p53 displayed on T7 phage.2008

    • Author(s)
      Ishi K, Sugawara F.
    • Journal Title

      Biochem Pharmacol 75(9)

      Pages: 1743-50

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of a methotrexate-binding peptide from a T7 phage display screen using a QCM device.2008

    • Author(s)
      Takakusagi Y, Kuroiwa Y, Sugawara F, Sakaguchi K.
    • Journal Title

      Bioorg Med Chem 52(3)

      Pages: 556-62

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of Small Molecule Binding Molecules by Affinity Purification Using a Specific Ligand Immobilized on PEGA Resin.2008

    • Author(s)
      Kuramochi K, Miyano Y, Enomoto Y, Takeuchi R, Ishi K, Takakusagi Y, Saitoh T, Fukudome K, Manita D, Takeda Y, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioconjug Chem 19(12)

      Pages: 2417-26

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] 1-Deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae.2008

    • Author(s)
      Naganuma M, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. Dec 25

      Pages: 2939-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Podophyllotoxin directly binds a hinge domain in E2 of HPV and inhibits an E2/E7 interaction in vitro.2008

    • Author(s)
      Saitoh T, Kuramochi K, Imai T, Takata KI, Takehara M, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioorg Med Chem. 16

      Pages: 5815-5825

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta.2008

    • Author(s)
      Mizushina Y, Manita D, Takeuchi T, Sugawara F, Kumamoto-Yonezawa Y, Matsui Y, Takemura M, Sasaki M, Yoshida H, Takikawa
    • Journal Title

      Molecules 14

      Pages: 102-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp.2008

    • Author(s)
      Kimura T, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. 16

      Pages: 4594-4599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Takakusagi Y, Sugawara F, Sakaguchi K, Yoshida H, Fujita M.
    • Journal Title

      Int J Mol Med. 21

      Pages: 281-290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha.2008

    • Author(s)
      Kuriyama I, Fukudome K, Kamisuki S, Kuramochi K, Tsubaki K, Sakaguchi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Int J Mol Med 22(6)

      Pages: 793-9

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] 1-Deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae.2008

    • Author(s)
      Naganuma M, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. 2 16

      Pages: 2939-2944

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of macrolide antibiotic-binding Human_p8 protein.2008

    • Author(s)
      Morimura T, Hashiba M, Kameda H, Takami M, Takahama H, Ohshige M, Sugawara F.
    • Journal Title

      J Antibiot (Tokyo) 61(5)

      Pages: 291-6

    • NAID

      10021927785

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp.2008

    • Author(s)
      Nishida M, Ida N, Horio M, Takeuchi T, Kamisuki S, Murata H, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem 16(9)

      Pages: 5115-22

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] The inhibitory action of SQDG (sulfoquinovosyl diacylglycerol) from spinach on Cdtl-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Hada T, Maeda N, Sugawara F, Yoshida H, Fujita M.
    • Journal Title

      Biochimie 90

      Pages: 947-956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Neoechinulin A protects PC12 cells against MPP+-induced cytotoxicity2008

    • Author(s)
      Kajimura Y, Aoki T, Kuramochi K, Kobayashi S, Sugawara F, Watanabe N, Arai T.
    • Journal Title

      J Antibiot (Tokyo). 61

      Pages: 291-296

    • NAID

      10021927874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of macrolide antibiotic-binding Human_p8 protein.2008

    • Author(s)
      Morimura T, Hashiba M, Kameda H, Takami M, Takahama H, Ohshige M, Sugawara F.
    • Journal Title

      J Antibiot (Tokyo). 61

      Pages: 291-296

    • NAID

      10021927785

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp.2008

    • Author(s)
      Kimura T, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem 16(8)

      Pages: 4594-9

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Neoechinulin A protects PC12 cells against MPP+-induced cytotoxicity.2008

    • Author(s)
      Kajimura Y, Aoki T, Kuramochi K, Kobayashi S, Sugawara F, Watanabe N, Arai T.
    • Journal Title

      J Antibiot (Tokyo) 61(5)

      Pages: 330-3

    • NAID

      10021927874

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells2008

    • Author(s)
      Kuriyama I, Mizuno T, Fukudome K, Kuramochi K, Tsubaki K, Usui T, Imamoto N, Sakaguchi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Molecules 13

      Pages: 2948-2961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Downregulation of Tie2 gene by a novel antitumor sulfolipid, 3'-sulfoquinovosyl-1'-monoacylglycerol, targeting angiogenesis.2008

    • Author(s)
      Mori Y, Sahara H, Matsumoto K, Takahashi N, Yamazaki T, Ohta K, Aoki S, Miura M, Sugawara F, Sakaguchi K, Sato N.
    • Journal Title

      Cancer Sci 99(5)

      Pages: 1063-70

    • NAID

      10024006631

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of Small Molecule Binding Molecules by Affinity Purification Using a Specific Ligand Immobilized on PEGA Resin2008

    • Author(s)
      Kuramochi K, Miyano Y, Enomoto Y, Takeuchi R, Ishi K, Takakusagi Y, Saitoh T, Fukudome K, Manita D, Takeda Y, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioconjug Chem. 19

      Pages: 2417-2426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] The inhibitory action of SQDG(sulfoquinovosyl diacylglycerol)from spinach on Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Hada T, Maeda N, Sugawara F, Yoshida H, Fujita M.
    • Journal Title

      Biochimie Mar 4(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] 1-Deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae.2008

    • Author(s)
      Naganuma M, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem 16(6)

      Pages: 2939-44

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Takakusagi Y, Sugawara F, Sakaguchi K, Yoshida H, Fujita M.
    • Journal Title

      Int J Mol Med. 21(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Syntheses and applications of fluorescent and biotinylated epolactaene derivatives : Epolactaene and its derivative induce disulfide formation.2008

    • Author(s)
      Kuramochi K, Yukizawa S, Ikeda S, Sunoki T, Arai S, Matsui R, Morita A, Mizushina Y, Sakaguchi K, Sugawara F, Ikekita M, Kobayashi S
    • Journal Title

      Bioorg Med Chem. 16

      Pages: 5039-5049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Takakusagi Y, Sugawara F, Sakaguchi K, Yoshida H, Fujita M.
    • Journal Title

      Int J Mol Med 21(3)

      Pages: 281-9

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Synthesis of Neoechinulin A and Derivatives.2008

    • Author(s)
      Kuranochi K, Aoki T, Nakazaki A, Kamisuki S, Takeno M, Ohnishi K, Kimoto K, Watanabe N, Kamakura T, Arai T, Sugawara F, Kobayashi K.
    • Journal Title

      Synthesis 23

      Pages: 3810-18

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Coenzyme Q(10) as a potent compound that inhibits Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Takakusagi Y, Yonezawa Y, Mizuno T, Yanagi K, Imamoto N, Sugawara F, Sakaguchi K, Yoshida H, Fujita M.
    • Journal Title

      Biochim Biophys Acta 1780(2)

      Pages: 203-13

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Structure-activity relationship of a glycolipid, sulfoquinovosyl diacylglycerol, with the DNA binding activity of p53.2007

    • Author(s)
      Iijima H, Kasai N, Chiku H, Takeuchi T, Kuramochi K, Hanashima S, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.
    • Journal Title

      Int J Mol Med. 19(1)

      Pages: 41-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of C10 biotinylated camptothecin (CPT-10-B) binding peptides using T7 phage display screen on a QCM device.2007

    • Author(s)
      Takakusagi Y, Takakusagi K, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K.
    • Journal Title

      Bioorg Med Chem 15(24)

      Pages: 7590-8

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp2007

    • Author(s)
      Kamisuki S, Ishimaru C, Onoda K, Kuriyama I, Ida N, Sugawara F, Yoshida H, Mizushina Y
    • Journal Title

      Bioorg Med Chem 15(9)

      Pages: 3109-3114

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Effects of a new immunosuppressive agent, beta-SQAG9, in swine kidney transplantation.2007

    • Author(s)
      Tanaka T, Kitamura H, Sahara H, Imai A, Itoh Y, Honma I, Sato E, Kobayashi K, Maeda T, Takenouchi M, Ohta K, Sugawara F, Sakaguchi K, Ando A, Inoko H, Sato N, Tsukamoto T.
    • Journal Title

      Transpl Immunol. 18

      Pages: 67-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.2007

    • Author(s)
      Maeda N, Kokai Y, Ohtani S, Sahara H, Kuriyama I, Kamisuki S, Takahashi S, Sakaguchi K, Sugawara F, Yoshida H, Sato N, Mizushina Y.
    • Journal Title

      Biochem Biophys Res Commun 352(2)

      Pages: 390-6

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Structure-activity relationship of a glycolipid, sulfoquinovosyl diacylglycerol, with the DNA binding activity of p53.2007

    • Author(s)
      Iijima H, Kasai N, Chiku H, Takeuchi T, Kuramochi K, Hanashima S, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y
    • Journal Title

      Int J Mol Med. 19

      Pages: 41-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic DNA polymerase I activity and cell growth of Escherichia coli.2007

    • Author(s)
      Furukawa T, Nishida M, Hada T, Kuramochi K, Sugawara F, Kobayashi S, Iijima H, Shimada H, Yoshida H, Mizushina Y.
    • Journal Title

      J Oleo Sci. 56

      Pages: 43-7

    • NAID

      130000055536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic polymerase I activity and cell growth of Escherichia coli.2007

    • Author(s)
      Furukawa T, Nishida M, Hada T, Kuramochi K, Sugawara F, Kobayashi S, Iijima H, Shimada H, Yoshida H, Mizushina Y.
    • Journal Title

      J Oleo Sci. 6(1)

      Pages: 43-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.2007

    • Author(s)
      Nakamura R, Takeuchi R, Kuramochi K, Mizushina Y, Ishimaru C, Takakusagi Y, Takemura M, Kobayashi S, Yoshida H, Sugawara F, Sakaguchi K.
    • Journal Title

      Org Biomol Chem. 5

      Pages: 3912-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Identification of C10 biotinylated camptothecin(CPT-10-B) binding peptides using T7 phage display screen on a QCM device.2007

    • Author(s)
      Takakusagi Y, Takakusagi K, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K.
    • Journal Title

      Bioorg Med Chem. 15

      Pages: 7590-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.2007

    • Author(s)
      Kamisuki S, Ishimaru C, Onoda K, Kuriyama I, Ida N, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. 15(9)

      Pages: 3109-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity Relationships of Neoechinulin A Analogues with Cytoprotection against Peroxynitrite-induced PC12 Cell Death.2007

    • Author(s)
      Kimoto K, Aoki T, Shibata Y, Kamisuki S, Sugawara F, Kuramochi K, Nakazaki A, Kobayashi S, Kuroiwa K, Watanabe N, Arai T.
    • Journal Title

      J Antibiot(Tokyo). 60

      Pages: 614-21

    • NAID

      10019777394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase.2007

    • Author(s)
      Mizushina Y, Dairaku I, Yanaka N, Takeuchi T, Ishimaru C, Sugawara F, Yoshida H, Kato N.
    • Journal Title

      Biochimie. 89(5)

      Pages: 581-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic polymerase I activity and cell growth of Escherichia coli.2007

    • Author(s)
      Furukawa T, Nishida M, Hada T, Kuramochi K, Sugawara F, Kobayashi S, Iijima H, Shimada H, Yoshida H, Mizushina Y
    • Journal Title

      J Oleo Sci. 6(1)

      Pages: 43-47

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase.2007

    • Author(s)
      Mizushina Y, Dairaku I, Yanaka N, Takeuchi T, Ishimaru C, Sugawara F, Yoshida H, Kato N.
    • Journal Title

      Biochimie 89(5)

      Pages: 581-90

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Sulfoglycolipids as candidate antiangiogenic radiosensitizers.2007

    • Author(s)
      Miura M, Sakimoto I, Ohta K, Sugawara F, Sakaguchi K.
    • Journal Title

      Anticancer Drugs. 18

      Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Sulfoglycolipids as candidate antiangiogenic radiosensitizers.2007

    • Author(s)
      Miura M, Sakimoto I, Ohta K, Sugawara F, Sakaguchi K.
    • Journal Title

      Anticancer Drugs. 18(1)

      Pages: 1-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha2007

    • Author(s)
      Maeda N, Kokai Y, Ohtani S, Sahara H, Kuriyama I, Kamisuki S, Takahashi S, Sakaguchi K, Sugawara F, Yoshida H, Sato N, Mizushina Y
    • Journal Title

      Biochem Biophys Res Commun. 352

      Pages: 390-396

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.2007

    • Author(s)
      Maeda N, Kokai Y, Ohtani S, Sahara H, Kuriyama I, Kamisuki S, Takahashi S, Sakaguchi K, Sugawara F, Yoshida H, Sato N, Mizushina Y.
    • Journal Title

      Biochem Biophys Res Commun. 352

      Pages: 390-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Structure-activity Relationships of Neoechinulin A Analogues with Cytoprotection against Peroxynitrite-induced PC12 Cell Death.2007

    • Author(s)
      Kimoto K, Aoki T, Shibata Y, Kamisuki S, Sugawara F, Kuramochi K, Nakazaki A, Kobayashi S, Kuroiwa K, Watanabe N, Arai T.
    • Journal Title

      J Antibiot (Tokyo) 60(10)

      Pages: 614-21

    • NAID

      10019777394

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Screening of paclitaxel-binding molecules from a library of random peptides displayed on T7 phage particles using paclitaxel-photoimmobilized resin.2007

    • Author(s)
      Aoki S, Morohashi K, Sunoki T, Kuramochi K, Kobayashi S, Sugawara F.
    • Journal Title

      Bioconjug Chem 18(6)

      Pages: 1981-6

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Effects of a new immunosuppressive agent, beta-SQAG9, in swine kidney transplantation.2007

    • Author(s)
      Tanaka T, Kitamura H, Sahara H, Imai A, Itoh Y, Honma I, Sato E, Kobayashi K, Maeda T, Takenouchi M, Ohta K, Sugawara F, Sakaguchi K, Ando A, Inoko H, Sato N, Tsukamoto T.
    • Journal Title

      Transpl Immunol 18(1)

      Pages: 67-71

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Sulfoglycolipids as candidate antiangiogenic radiosensitizers. Miura M, Sakimoto I, Ohta K, Sugawara F, Sakaguchi K.2007

    • Author(s)
      Miura M, Sakimoto I, Ohta K, Sugawara F, Sakaguchi K
    • Journal Title

      Anticancer Drugs 18(1)

      Pages: 1-5

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationship of a glycolipid, sulfoquinovosyl diacylglycerol, with the DNA binding activity of p532007

    • Author(s)
      Iijima H, Kasai N, Chiku H, Takeuchi T, Kuramochi K, Hanashima S, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y
    • Journal Title

      Int J Mol Med 19(1)

      Pages: 41-48

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Inhibitory action of polyunsaturated fatty acids on IMP dehy drogenase.2007

    • Author(s)
      Mizushina Y, Dairaku I, Yanaka N, Takeuchi T, Ishimaru C, Sugawara F, Yoshida H, Kato N.
    • Journal Title

      Biochimie. 89

      Pages: 581-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Sulfoglycolipids as candidate antiangiogenic radiosensitizers2007

    • Author(s)
      Miura M, Sakimoto I, Ohta K, Sugawara F, Sakaguchi K.
    • Journal Title

      Anticancer Drugs 18(1)

      Pages: 1-5

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] An approach to evaluate two-electron reduction of 9, 10-phenanthraquinone and redox activity of the hydroquinone associated with oxidative stress.2007

    • Author(s)
      Taguchi K, Fujii S, Yamano S, Cho AK, Kamisuki S, Nakai Y, Sugawara F, Froines JR, Kumagai Y.
    • Journal Title

      Free Radic Biol Med. 43

      Pages: 789-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.2007

    • Author(s)
      Nakamura R, Takeuchi R, Kuramochi K, Mizushina Y, Ishimaru C, Takakusagi Y, Takemura M, Kobayashi S, Yoshida H, Sugawara F, Sakaguchi K.
    • Journal Title

      Org Biomol Chem 5(24)

      Pages: 3912-21

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.2007

    • Author(s)
      Maeda N, Kokai Y, Ohtani S, Sahara H, Kuriyama I, Kamisuki S, Takahashi S, Sakaguchi K, Sugawara F, Yoshida H, Sato N, Mizushina Y.
    • Journal Title

      Biochem Biophys Res Commun. 352

      Pages: 390-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Screening of paclitaxel-binding molecules from a library of random peptides displayed on T7 phage particles using paclitaxel-photoimmobilized resin.2007

    • Author(s)
      Aoki S, Morohashi K, Sunoki T, Kuramochi K, Kobayashi S, Sugawara F.
    • Journal Title

      Bioconjug Chem. 18

      Pages: 1981-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] An approach to evaluate two-electron reduction of 9, 10-phenanthraquinone and redox activity of the hydroquinone associated with oxidative stress.2007

    • Author(s)
      Taguchi K, Fujii S, Yamano S, Cho AK, Kamisuki S, Nakai Y, Sugawara F, Froines JR, Kumagai Y.
    • Journal Title

      Free Radic Biol Med 43(5)

      Pages: 789-99

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.2007

    • Author(s)
      Kamisuki S, Ishimaru C, Onoda K, Kuriyama I, Ida N, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem 15(9)

      Pages: 3109-14

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase.2007

    • Author(s)
      Mizushina Y, Dairaku I, Yanaka N, Takeuchi T, Ishimaru C, Sugawara F, Yoshida H, Kato N
    • Journal Title

      Biochimie 89(5)

      Pages: 581-590

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationship of a glycolipid, sulfoquinovosyl diacylglycerol, with the DNA binding activity of p53.2007

    • Author(s)
      Iijima H, Kasai N, Chiku H, Takeuchi T, Kuramochi K, Hanashima S, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.
    • Journal Title

      Int J Mol Med 19(1)

      Pages: 41-8

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.2007

    • Author(s)
      Kamisuki S, Ishimaru C, Onoda K, Kuriyama I, Ida N, Sugawara F, Yoshida H, Mizushina Y.
    • Journal Title

      Bioorg Med Chem. 15

      Pages: 3109-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Synthesis and absolute configuration of (+)-pseudodeflectusin : structural revision of aspergione B.2006

    • Author(s)
      Saito F, Kuramochi K, Nakazaki A, Mizushina Y, Sugawara F, Kobayashi S
    • Journal Title

      Euro J Org Chem. 21

      Pages: 4796-4799

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] A high-throughput phage display screening method using a combination of real-time PCR and affinity chromatography2006

    • Author(s)
      Morohashi K, Arai T, Saito S, Watanabe M, Sakaguchi K, Sugawara F.
    • Journal Title

      Comb Chem High Throughput Screen 9・1

      Pages: 55-61

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The inhibitory action of long-chain fatty acids on the DNA binding activity of p53.2006

    • Author(s)
      Iijima H, Kasai N, Chiku H, Murakami S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.
    • Journal Title

      Lipids. 41(6)

      Pages: 521-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Total synthesis and stereochemistry of the antitumor antibiotics PD 113,2712006

    • Author(s)
      Takeuchi T, Kuramochi K, Kobayashi S, Sugawara F
    • Journal Title

      Org Lett. 8

      Pages: 5307-5310

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Total synthesis of (-)-neoechinulin A2006

    • Author(s)
      Aoki T, Kamisuki S, Kimoto M, Ohnishi K, Takakusagi Y, Kuracmohi K, Takeda Y, Nakazaki A, Kuroiwa K, Ohuchi T, Sugawara F, Arai T, Kobayashi S
    • Journal Title

      Synlett. 2006

      Pages: 677-680

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Total synthesis and stereochemistry of the antitumor antibiotics PD 113,271.2006

    • Author(s)
      Takeuchi T, Kuramochi K, Kobayashi S, Sugawara F.
    • Journal Title

      Org Lett. Nov 9;8(23)

      Pages: 5307-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of Antibiotic Clarithromycin Binding Peptide Displayed by T7 Phage Particles.2006

    • Author(s)
      Morimura T, Noda N, Kato Y, Watanabe T, Saitoh T, Yamazaki T, Takata K, Aoki S, Ohta K, Ohshige M, Sakaguchi K, Sugawara F
    • Journal Title

      J Antibiot. 59

      Pages: 625-632

    • NAID

      10018348585

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] A high-throughput phage display screening method using a combination of real-time PCR and affinity chromatography.2006

    • Author(s)
      Morohashi K, Arai T, Saito S, Watanabe M, Sakaguchi K, Sugawara F
    • Journal Title

      Comb Chem High Throughput Screen. 9

      Pages: 55-61

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of Antibiotic Clarithromycin Binding Peptide Displayed by T7 Phage Particles.2006

    • Author(s)
      Morimura T, Noda N, Kato Y, Watanabe T, Saitoh T, Yamazaki T, Takata K, Aoki S, Ohta K, Ohshige M, Sakaguchi K, Sugawara F.
    • Journal Title

      J Antibiot. 59(10)

      Pages: 625-632

    • NAID

      10018348585

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Total synthesis of (-)-neoechinulin A2006

    • Author(s)
      Toshiaki Aoki, Shinji Kamisuki, Masaaki Kimoto, Kensuke Ohnishi, Yoichi Takakusagi, Kouji Kuracmohi, Yoshifumi Takeda, Atsuo Nakazaki, Kenji Kuroiwa, Takashi Ohuchi, Fumio Sugawara, Takao Arai, Susumu Kobayashi
    • Journal Title

      Synlett. 2006

      Pages: 677-680

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic DNA polymerase I activity and cell growth of Escherichia coli.2006

    • Author(s)
      Furukawa T, Nishida M, Hada T, Kuramochi K, Sugawara F, Kobayashi S, Iijima H, Shimada H, Yoshida H, Mizushina Y.
    • Journal Title

      J Oleo Sci 56(1)

      Pages: 43-7

    • NAID

      130000055536

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Journal Article] Structural analysis of mogrol and its glycoside as inhibitors of animal DNA polymerase and human cancer cell growth.2006

    • Author(s)
      Mizushina Y, Akihisa T, Hayakawa Y, Takeuchi T, Kuriyama I, Yonezawa Y, Takemura M, Kato I, Sugawara F, Yoshida H.
    • Journal Title

      Letters in Drug & Discovery. 3

      Pages: 253-60

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Total synthesis of (-)-neoechinulin A.2006

    • Author(s)
      Aoki T, Kamisuki S, Kimoto M, Ohnishi K, Takakusagi Y, Kuracmohi K, Takeda Y, Nakazaki A, Kuroiwa K, Ohuchi T, Sugawara F, Arai T, Kobayashi S.
    • Journal Title

      Synlett.

      Pages: 677-680

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] 5-(Hydroxymethyl)-2-furfural : a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.2006

    • Author(s)
      Mizushina Y, Yagita E, Kuramochi K, Kuriyama I, Shimazaki N, Koiwai O, Uchiyama Y, Yomezawa Y, Sugawara F, Kobayashi S, Sakaguchi K, Yoshida H
    • Journal Title

      Arch Biochem Biophys. 446

      Pages: 69-76

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of mogrol and its glycoside as inhibitors of animal DNA polymerase and human cancer cell growth.2006

    • Author(s)
      Mizushina Y, Akihisa T, Hayakawa Y, Takeuchi T, Kuriyama I, Yonezawa Y, Takemura M, Kato I, Sugawara F, Yoshida H
    • Journal Title

      Letters in Drug & Discovery 3

      Pages: 253-260

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] In vivo target molecule screening of a bioactive natural product..2006

    • Author(s)
      Aoki S, Ohta K, Sugawara F, Sakaguchi K
    • Journal Title

      Proceedings of Sapporo Medicinal School. 6

      Pages: 27-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] An emulsion of sulfoquinovosylacylglycerol with long-chain alkanes increases its permeability to tumor cells.2006

    • Author(s)
      Aoki S, Ohta K, Matsumoto K, Sakai H, Abe M, Miura M, Sugawara F, Sakaguchi K.
    • Journal Title

      J Membr Biol. 213(1)

      Pages: 11-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] An emulsion of sulfoquinovosylacylglycerol with long-chain alkanes increases its permeability to tumor cells.2006

    • Author(s)
      Aoki S, Ohta K, Matsumoto K, Sakai H, Abe M, Miura M, Sugawara F, Sakaguchi K
    • Journal Title

      J Membr Biol. 213

      Pages: 11-18

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] 生理活性物質Sulfoquinovosylacylglycerolの生体内標的分子検索2006

    • Author(s)
      Satoko Aoki, Keisuke Ohta, F.Sugawara, K.Sakaguchi
    • Journal Title

      札幌医科大学医学部付属臨海医学研究所紀要 6

      Pages: 27-34

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8kDa domain of DNA polymerase beta.2006

    • Author(s)
      Murakami S, Kamisuki S, Takata K, Kasai N, Kimura S, Mizushina Y, Ohta K, Sugawara F, Sakaguchi K
    • Journal Title

      Biochem Biophys Res Commun. 350

      Pages: 7-16

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster.2006

    • Author(s)
      Ruike T, Takeuchi R, Takata K, Oshige M, Kasai N, Shimanouchi K, Kanai Y, Nakamura R, Sugawara F, Sakaguchi K.
    • Journal Title

      FEBS J. Nov;273(22)

      Pages: 5062-73

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The in vitro and in vivo inhibitory effect of dehydroaltenusin : a specific inhibitor of mammalian DNA polymerase a.2006

    • Author(s)
      Maeda N, Kamisuki S, Takahashi S, Yoshida H, Sakaguchi K, Sugawara F, Mizushina Y
    • Journal Title

      Current Bioactive Compound. 2

      Pages: 3-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Alpha-sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis.2006

    • Author(s)
      Sakimoto I, Ohta K, Yamazaki T, Ohtani S, Sahara H, Sugawara F, Sakaguchi K, Miura M.
    • Journal Title

      Cancer Res. 66・4

      Pages: 2287-2295

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] 5-(Hydroxyraethyl)-2-furfural : a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.2006

    • Author(s)
      Mizushina Y, Yagita E, Kuramochi K, Kuriyama I, Shimazaki N, Koiwai O, Uchiyama Y, Yomezawa Y, Sugawara F, Kobayashi S, Sakaguchi K, Yoshida H.
    • Journal Title

      Arch Biochem Biopnys. 446・1

      Pages: 69-76

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.2006

    • Author(s)
      Takeuchi T, Ishidoh T, Iijima H, Kuriyama I, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y
    • Journal Title

      Genes Cells. 11

      Pages: 223-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda2006

    • Author(s)
      Takeuchi T, Ishidoh T, Iijima H, Kuriyama I, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y
    • Journal Title

      Genes Cells. 11

      Pages: 223-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster.2006

    • Author(s)
      Ruike T, Takeuchi R, Takata K, Oshige M, Kasai N, Shimanouchi K, Kanai Y, Nakamura R, Sugawara F, Sakaguchi K
    • Journal Title

      FEBS J. 273

      Pages: 5062-5073

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The in vitro and in vivo inhibitory effect of dehydroaltenusin : a specific inhibitor of mammalian DNA polymerase α.2006

    • Author(s)
      Maeda N, Kamisuki S, Takahashi S, Yoshida H, Sakaguchi K, Sugawara F, Mizushina Y
    • Journal Title

      Current Bioactive Compound. 2

      Pages: 3-11

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] A high-throughput phage display screening method using a combination of real-time PCR and affinity chromatography.2006

    • Author(s)
      Morohashi K, Arai T, Saito S, Watanabe M, Sakaguchi K, Sugawara F.
    • Journal Title

      Comb Chem High Throughput Screen. 9(1)

      Pages: 55-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Alpha-sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis.2006

    • Author(s)
      Sakimoto I, Ohta K, Yamazaki T, Ohtani S, Sahara H, Sugawara F, Sakaguchi K, Miura M.
    • Journal Title

      Cancer Res. 15;66(4)

      Pages: 2287-95

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8kDadomain of DNA polymerase beta.2006

    • Author(s)
      Murakami S, Kamisuki S, Takata K, Kasai N, Kimura S, Mizushina Y, Ohta K, Sugawara F, Sakaguchi K
    • Journal Title

      Biochem Biophys Res Commun. 350

      Pages: 7-16

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.2006

    • Author(s)
      Takeuchi T, Ishidoh T, Iijima H, Kuriyama I, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.
    • Journal Title

      Genes Cells. 11(3)

      Pages: 223-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of cureumin derivatives binding to the BRCT domain of human DNA polymerase lambda.2006

    • Author(s)
      Takeuchi T, Ishidoh T, Iijima H, Kuriyama I, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y
    • Journal Title

      Genes Cells. 11

      Pages: 223-35

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The inhibitory action of long-chain fatty acids on the DNA binding activity of p53.2006

    • Author(s)
      Iijima H, Kasai N, Chiku H, Murakami S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y
    • Journal Title

      Lipids. 41

      Pages: 521-527

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of plakevulin A and structure-activity relationships of its related compounds against DNA polymerases.2006

    • Author(s)
      Kuramochi K, Saito F, Takeuchi R, Era T, Takemura M, Kobayashi J, Sakaguchi K, Kobayashi S, Sugawara F
    • Journal Title

      Tertrahedron 62

      Pages: 8006-8015

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Alpha-sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis.2006

    • Author(s)
      Sakimoto I, Ohta K, Yamazaki T, Ohtani S, Sahara H, Sugawara F, Sakaguchi K, Miura M
    • Journal Title

      Cancer Res. 15

      Pages: 2287-2295

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8kDa domain of DNA polymerase beta..2006

    • Author(s)
      Murakami S, Kamisuki S, Takata K, Kasai N, Kimura S, Mizushina Y, Ohta K, Sugawara F, Sakaguchi K
    • Journal Title

      Biochem Biophys Res Commun. 350(1)

      Pages: 7-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis and absolute configuration of (+)-pseudodeflectusin : structural revision of aspergione B.2006

    • Author(s)
      F.Saito, K.Kuramochi, A.Nakazaki, Y.Mizushina, F.Sugawara, S.Kobayashi.
    • Journal Title

      Euro J. Org. Chem. 21

      Pages: 4796-4799

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Abstract Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.2006

    • Author(s)
      Takeuchi T, Ishidoh T, Iijima H, Kuriyama I, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y.
    • Journal Title

      Genes Cells. 11・3

      Pages: 223-235

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of plakevulin A and structure-activity relationships of its related compounds against DNA polymerases.2006

    • Author(s)
      Kuramochi K., Saito F., Takeuchi R., Era T., Takemura M., Kobayashi J., Sakaguchi K., Kobayashi S., Sugawara.F.
    • Journal Title

      Tertrahedron 62

      Pages: 8006-15

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] 5-(Hydroxymethyl)-2-furfural : a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.2006

    • Author(s)
      Mizushina Y, Yagita E, Kuramochi K, Kuriyama I, Shimazaki N, Koiwai O, Uchiyama Y, Yomezawa Y, Sugawara F, Kobayashi S, Sakaguchi K, Yoshida H.
    • Journal Title

      Arch Biochem Biophys. 446(1)

      Pages: 69-76

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.2006

    • Author(s)
      Takeuchi T, Ishidoh T, Iijima H, Kuriyama I, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H, Mizushina Y
    • Journal Title

      Genes Cells. 11(3)

      Pages: 223-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Selective inhibitors of terminal deoxyribonucleotidyltransferase(TdT) : baicalin and genistin.2005

    • Author(s)
      Uchiyama Y, Tagami J, Kamisuki S, Kasai N, Oshige M, Chiku H, Ibe S, Koiwai O, Sugawara F, Sakaguchi K.
    • Journal Title

      Biochim Biophys Acta. 1725・3

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors.2005

    • Author(s)
      Mizushina Y, Akihisa T, Ukiya M, Hamasaki Y, Murakami-Nakai C, Kuriyama I, Takeuchi T, Sugawara F, Yoshida H.
    • Journal Title

      Life Sci. 77

      Pages: 2127-40

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta.2005

    • Author(s)
      Kasai N, Mizushina Y, Murata H, Yamazaki T, Ohkubo T, Sakaguchi K, Sugawara F.
    • Journal Title

      FEBS J. 272・17

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Monolayer membranes and bilayer vesicles characterized by alpha-and beta-anomer of sulfoquinovosyldiacyglycerol (SODG).2005

    • Author(s)
      Matsumoto K, Sakai H, Ohta K, Kameda H, Sugawara F, Abe M, Sakaguchi K
    • Journal Title

      Chem Phys Lipids. 133(2)

      Pages: 203-214

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition.2005

    • Author(s)
      Matsumoto K, Sakai H, Takeuchi R, Tsuchiya K, Ohta K, Sugawara F, Abe M, Sakaguchi K.
    • Journal Title

      Colloids Surf B Biointerfaces. 46(3)

      Pages: 175-81

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Mechanism of the immunosuppressive effect in vivo of novel immunosuppressive drug beta-SQAG9, which inhibits the response of the CD62L+ T-cell subset.2005

    • Author(s)
      Takenouchi M, Sahara H, Yamamoto Y, Matsumoto Y, Imai A, Fujita T, Tamura Y, Takahashi N, Gasa S, Matsumoto K, Ohta K, Sugawara F, Sakaguchi K, Jimbow K, Sato N
    • Journal Title

      Transplant Proc. 37(1)

      Pages: 139-142

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Mammalian mitotic centromere-associated kinesin(MCAK) : a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents.2005

    • Author(s)
      Aoki S, Ohta K, Yamazaki T, Sugawara F, Sakaguchi K.
    • Journal Title

      FEBS J. 272・9

      Pages: 2132-2140

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.2005

    • Author(s)
      Mizushina Y, Kuramochi K, Ikawa H, Kuriyama I, Shimazaki N, Takemura M, Oshige M, Yoshida H, Koiwai O, Sugawara F, Kobayashi S, Sakaguchi K.
    • Journal Title

      Int J Mol Med. 15・5

      Pages: 785-793

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of a drug target motif : an anti-tumor drug NK109 interacts with a PNxxxxP.2005

    • Author(s)
      Morohashi K, Yoshino A, Yoshimori A, Saito S, Tanuma S, Sakaguchi K, Sugawara F.
    • Journal Title

      Biochem Pharmacol. 70・1

      Pages: 37-46

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors.2005

    • Author(s)
      Mizushina Y, Saito A, Tanaka A, Nakajima N, Kuriyama I, Takemura M, Takeuchi T, Sugawara F, Yoshida H
    • Journal Title

      Biochem Biophys Res Commun. 333(1)

      Pages: 101-109

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] hEP1 Receptor Third Cytoplasmic Loop : A New Target for Camptothecin Identified by Phage Display Technology2005

    • Author(s)
      Yoichi Takakusagi, Keisuke Ohta, Kouji Kuramochi, Kengo Morohashi, Susumu Kobayashi, Kengo Sakaguchi, Fumio Sugawara
    • Journal Title

      Biochemistry (In press)

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] The entrapment of kojic oleate in bilayer vesicles2005

    • Author(s)
      Manosroi A, Wongtrakul P, Manosroi J, Midorikawa U, Hanyu Y, Yuasa M, Sugawara F, Sakai H, Abe M.
    • Journal Title

      Int J Pharm. 298・1

      Pages: 13-25

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition.2005

    • Author(s)
      Matsumoto K, Sakai H, Takeuchi R, Tsuchiya K, Ohta K, Sugawara F, Abe M, Sakaguchi K
    • Journal Title

      Colloids Surf B Biointerfaces 46(3)

      Pages: 175-181

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Mammalian mitotic centromere-associated kinesin (MCAK), a new molecular target of sulfoquinovosylacylglycerols (SQAGs), novel anti-tumor and immunosuppressive agents2005

    • Author(s)
      Aoki S, Kamisuki S, Ohta S, Sugawara F, Sakaguchi K
    • Journal Title

      FEBS J. (In press)

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Mammalian mitotic centromere-associated kinesin (MCAK) : a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents.2005

    • Author(s)
      Aoki S, Ohta K, Yamazaki T, Sugawara F, Sakaguchi K
    • Journal Title

      FEBS J. 272(9)

      Pages: 2132-2140

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Three-dimensional structural analysis of the binding site of two inhibitors, nervonic acid and lithocholic acid, of DNA polymerase β and DNA topoisomerase II.2005

    • Author(s)
      Mizushina Y, Kasai N, Sugawara F, Yoshida H, Sakaguchi K.
    • Journal Title

      Current Computer-Aided Drug Design 1

      Pages: 9-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT) : baicalin and genistin.2005

    • Author(s)
      Uchiyama Y, Tagami J, Kamisuki S, Kasai N, Oshige M, Chiku H, Ibe S, Koiwai O, Sugawara F, Sakaguchi K.
    • Journal Title

      Biochim. Biophys. Acta 1725(3)

      Pages: 298-304

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent.2005

    • Author(s)
      Mizushina Y, Kasai N, Iijima H, Sugawara F, Yoshida H, Sakaguchi K
    • Journal Title

      Curr Med Chem Anticancer Agents 5(6)

      Pages: 613-625

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors.2005

    • Author(s)
      Mizushina Y, Saito A, Tanaka A, Nakajima N, Kuriyama I, Takemura M, Takeuchi T, Sugawara F, Yoshida H.
    • Journal Title

      Biochem. Biophys. Res. Commun. 333

      Pages: 101-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Sulfo-quinovosyl-acyl-glycerol(SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent.2005

    • Author(s)
      Mizushina Y, Kasai N, Iijima H, Sugawara F, Yoshida H, Sakaguchi K.
    • Journal Title

      Curr Med Chem Anticancer Agents 5・6

      Pages: 613-625

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Monolayer membranes and Bilayer vesicles characterized by alpha- and beta-anomer of sulfoquinovosyldiacyglycerol(SQDG).2005

    • Author(s)
      Matsumoto K, Sakai H, Ohta K, Kameda H, Sugawara F, Abe M, Sakaguchi K.
    • Journal Title

      Chem Phys Lipids. 133・2

      Pages: 203-214

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Monoacetylcurcumin : a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography..2005

    • Author(s)
      Mizushina Y, Ishidoh T, Takeuchi T, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H
    • Journal Title

      Biochem Biophys Res Commun. 337(4)

      Pages: 1288-95

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of a drug target motif : an anti-tumor drug NK109 interacts with a PNxxxxP.2005

    • Author(s)
      Morohashi K, Yoshino A, Yoshimori A, Saito S, Tanuma S, Sakaguchi K, Sugawara F
    • Journal Title

      Biochem Pharmacol. 70(1)

      Pages: 37-46

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta.2005

    • Author(s)
      Kasai N, Mizushina Y, Murata H, Yamazaki T, Ohkubo T, Sakaguchi K, Sugawara F
    • Journal Title

      FEBS J. 272(12)

      Pages: 4349-4361

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Effective form of sulfoquinovosyldlacyglycerol(SQDG) vesicles for DNA polymerase inhibition.2005

    • Author(s)
      Matsumoto K, Sakai H, Takeuchi R, Tsuchiya K, Ohta K, Sugawara F, Abe M, Sakaguchi K.
    • Journal Title

      Colloids Surf B Biointerfaces. 46・3

      Pages: 175-181

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] hEP1 Receptor Third Cytoplasmic Loop : A New Target for Camptothecin Identified by Phage Display Technology2005

    • Author(s)
      Yoichi Takakusagi, Keisuke Ohta, Kouji Kuramochi, Kengo Morohashi, Susumu Kobayashi, Kengo Sakaguchi, Fumio Sugawara
    • Journal Title

      Biochemistry (In press)

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of a biotinylated camptothecin derivative and determination of the binding sequence by T7 phage display technology.2005

    • Author(s)
      Takakusagi Y, Ohta K, Kuramochi K, Morohashi K, Kobayashi S, Sakaguchi K, Sugawara F
    • Journal Title

      Bioorg Med Chem Lett. 15(21)

      Pages: 4846-4849

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Inhibition of CD62L+ T-cell response in vitro via a novel sulfo-glycolipid, beta-SQAG9 liposome that binds to CD62L molecule on the cell surface.2005

    • Author(s)
      Yamamoto Y, Sahara H, Takenouchi M, Matsumoto Y, Imai A, Fujita T, Tamura Y, Takahashi N, Gasa S, Matsumoto K, Ohta K, Sugawara F, Sakaguchi K, Jimbow K, Sato N.
    • Journal Title

      Cell Immuno 232・1-2

      Pages: 105-115

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Affinity capture of a mammalian DNA polymerase p by inhibitors immobilized to resins used in solid-phase organic synthesis.2005

    • Author(s)
      Kuramochi K, Haruyama Y, Takeuchi R, Sunoki T, Watanabe M, Oshige M, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioconjugate Chem. 16

      Pages: 203-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors.2005

    • Author(s)
      Mizushina Y, Saito A, Tanaka A, Nakajima N, Kuriyama I, Takemura M, Takeuchi T, Sugawara F, Yoshida H.
    • Journal Title

      Biochem Biophys Res Commun. 333・1

      Pages: 101-109

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.2005

    • Author(s)
      Mizushina Y, Kuramochi K, Ikawa H, Kuriyama I, Shimazaki N, Takemura M, Oshige M, Yoshida H, Koiwai O, Sugawara F, Kobayashi S, Sakaguchi K
    • Journal Title

      Int J Mol Med. 15(5)

      Pages: 785-793

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase β.2005

    • Author(s)
      Kasai N, Mizushina Y, Murata H, Yamazaki T, Ohkubo T, Sakaguchi K, Sugawara F.
    • Journal Title

      FEBS J. 272

      Pages: 4349-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Monolayer membranes and bilayer vesicles characterized by α- and β-anomer of sulfoquinovosyldiacyglycerol (SQDG).2005

    • Author(s)
      Matsumoto K, Sakai H, Ohta K, Kameda H, Sugawara F, Abe M, Sakaguchi K.
    • Journal Title

      Chemistry and Physics of Lipids. (In press)

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent..2005

    • Author(s)
      Mizushina Y, Kasai N, Iijima H, Sugawara F, Yoshida H, Sakaguchi K
    • Journal Title

      Curr Med Chem Anticancer Agents. 5(6)

      Pages: 613-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Abstract Monoacetylcurcumin : a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.2005

    • Author(s)
      Mizushina Y, Ishidoh T, Takeuchi T, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H.
    • Journal Title

      Biochem Biopnys Res Commun. 337・4

      Pages: 1288-1295

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Camptothecin binds to a synthetic peptide identified by a T7 phage display screen.2005

    • Author(s)
      Takakusagi Y, Kobayashi S, Sugawara F
    • Journal Title

      Bioorg Med Chem Lett. 15(21)

      Pages: 4850-4853

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Monoacetylcurcumin : a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.2005

    • Author(s)
      Mizushina Y, Ishidoh T, Takeuchi T, Shimazaki N, Koiwai O, Kuramochi K, Kobayashi S, Sugawara F, Sakaguchi K, Yoshida H
    • Journal Title

      Biochem Biophys Res Commun. 337(4)

      Pages: 1288-1289

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Monolayer membranes and bilayer vesicles characterized by α- and β-anomer of sulfoquinovosyldiacylglycerol (SQDG).2005

    • Author(s)
      Matsumoto K, Sakai H, Ohta K, Kameda H, Sugawara F, Abe M, Sakaguchi K.
    • Journal Title

      Chem. Phys. Lipids. 133

      Pages: 203-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article]2005

    • Author(s)
      Takakusagi Y, Onta K, Kuramochi K, Morohashi K, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioorg Med Chem Lett. 15・21

      Pages: 4846-4849

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Affinity capture of a mammalian DNA polymerase beta by inhibitors immobilized to resins used in solid-phase organic synthesis.2005

    • Author(s)
      Kuramochi K, Haruyama T, Takeuchi R, Sunoki T, Watanabe M, Oshige M, Kobayashi S, Sakaguchi K, Sugawara F
    • Journal Title

      Bioconjug Chem. 16(1)

      Pages: 97-104

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Camptotnecin binds to a synthetic peptide identified by a T7 phage display screen.2005

    • Author(s)
      Takakusagi Y, Kobayasni S, Sugawara F.
    • Journal Title

      Bioorg Med Chem Lett. 15・21

      Pages: 4850-4853

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT) : baicalin and genistin.2005

    • Author(s)
      Uchiyama Y, Tagami J, Kamisuki S, Kasai N, Oshige M, Chiku H, Ibe S, Koiwai O, Sugawara F, Sakaguchi K
    • Journal Title

      Biochim Biophys Acta. 1725(3)

      Pages: 298-304

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Affinity capture of a mammalian DNA polymerase β by inhibitors immobilized to resins used in solid-phase organic synthesis.2005

    • Author(s)
      Kuramochi K, Haruyama Y, Takeuchi R, Sunoki T, Watanabe M, Oshige M, Kobayashi S, Sakaguchi K, Sugawara F
    • Journal Title

      Bloconjugate Chemistry. 16:97

      Pages: 97-104

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] 生理活性物質Sulfoquinovosylacylglycerolの生体内標的分子検索.2005

    • Author(s)
      Aoki S, Ohta K, Sugawara F., Sakaguchi K.
    • Journal Title

      札幌医科大学医学部付属臨海医学研究所紀要 6

      Pages: 27-34

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Mechanism of the immunosuppressive effect in vivo of novel immunosuppressive drug beta-SQAG9, which inhibits the response of the CD62L+ T-cell subset.2005

    • Author(s)
      Takenouchi M, Sahara H, Yamamoto Y, Matsumoto Y, Imai A, Fujita T, Tamura Y, Takahashi N, Gasa S, Matsumoto K, Ohta K, Sugawara F, Sakaguchi K, Jimbow K, Sato N.
    • Journal Title

      Transplant. Proc. 37

      Pages: 139-42

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors.2005

    • Author(s)
      Mizushina Y, Akihisa T, Ukiya M, Hamasaki Y, Murakami-Nakai C, Kuriyama I, Takeuchi T, Sugawara F, Yoshida H
    • Journal Title

      Life Sci. 77(17)

      Pages: 2127-2140

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of a drug target motif : an anti-tumor drug NK109 interacts with a PNxxxxP motif2005

    • Author(s)
      Kengo Morohashi, Ayako Yoshino, Atsushi Yoshimori, Seiichi Saito, Seiichi Tanuma, Kengo Sakaguchi, Fumio Sugawara
    • Journal Title

      Biochem.Pharmacol. (In press)

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Mechanism of the immunosuppressive effect in vivo of novel Immunosuppressive drug beta-SQAG9, which nhibits the response of the CD62L+T-cell subset.2005

    • Author(s)
      Takenouchi M, Sahara H, Yamaiaoto Y, Matsumoto Y, Imai A, Fujita T, Tamura Y, Takahashi N, Gasa S, Matsumoto K, Ohta K, Sugawara F, Sakaguchi K, Jimbow K, Sato N.
    • Journal Title

      Transplant Proc. 37・1

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of a biotinylated camptothecin derivative and determination of the binding sequence by T7 phage display technology.2005

    • Author(s)
      Takakusagi Y, Ohta K, Kuramochi K, Morohashi K, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioorg. Med. Chem. Lett. 15

      Pages: 4846-49

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Three-dimensional structural analysis of the binding site of two inhibitors, nervonic acid and lithocholic acid, of DNA polymerase βand DNA topoisomerase II.2005

    • Author(s)
      Mizushina Y, Kasai N, Sugawara F, Yoshida H, Sakaguchi K
    • Journal Title

      Current Computer-Aided Drug Design 1

      Pages: 9-91

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Camptothecin binds to a synthetic peptide identified by a T7 phage display screen.2005

    • Author(s)
      Takakusagi Y, Kobayashi S, Sugawara F.
    • Journal Title

      Bioorg. Med. Chem. Lett. 15

      Pages: 4850-53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The entrapment of kojic oleate in bilayer vesicles. Manosroi A2005

    • Author(s)
      Wongtrakul P, Manosroi J, Midorikawa U, Hanyu Y, Yuasa M, Sugawara F, Sakai H, Abe M.
    • Journal Title

      Int J Pharm. 298(1)

      Pages: 13-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Affinity capture of a mammalian DNA polymerase beta by inhibitors immobilized to resins used in solid-phase organic synthesis.2005

    • Author(s)
      Kuramochi K, Haruyama T, Takeuchi R, Sunoki T, Watanabe M, Oshige M, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioconjug Chem. 16・1

      Pages: 97-104

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisoraerase inhibitors.2005

    • Author(s)
      Mizushina Y, Akihisa T, Ukiya M, Hamasaki Y, Murakami-Nakai C, Kuriyama I, Takeuchi T, Sugawara F, Yoshida H.
    • Journal Title

      Life Sci. 77.17

      Pages: 2127-2140

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of a drug target motif : An anti-tumor drug NK109 interacts with a PNxxxxP.2005

    • Author(s)
      Morohashi K, Yoshino A, Yoshimori A, Saito S, Tanuma S, Sakaguchi K, Sugawara F.
    • Journal Title

      Biochem. Pharmacol. 70

      Pages: 37-46

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Identification of a drug target motif : an anti-tumor drug NK109 interacts with a PNxxxxP motif2005

    • Author(s)
      Kengo Morohashi, Ayako Yoshino, Atsushi Yoshimori, Seiichi Saito, Seiichi Tanuma, Kengo Sakaguchi, Fumio Sugawara
    • Journal Title

      Biochem.Pharmacol. (In press)

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Mammalian mitotic centromere-associated kinesin (MCAK), a new molecular target of sulfoquinovosylacylglycerols (SQAGs), novel anti-tumor and immunosuppressive agents2005

    • Author(s)
      Aoki S, Kamisuki S, Ohta S, Sugawara F, Sakaguchi K
    • Journal Title

      FEBS J. (In press)

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Mammalian mitotic centromere-associated kinesin (MCAK), a new molecular target of sulfoquinovosylacylglycerols (SQAGs), novel anti-tumor and immunosuppressive agents.2005

    • Author(s)
      Aoki S, Kamisuki S, Ohta S, Sugawara F, Sakaguchi K.
    • Journal Title

      FEBS J. 272

      Pages: 2132-40

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Monolayer membranes and bilayer vesicles characterized by α- and β-anomer of sulfoquinovosyldiacyglycerol (SQDG).2005

    • Author(s)
      Matsumoto.K, Sakai H, Ohta K, Kameda H, Sugawara F, Abe M, Sakaguchi K.
    • Journal Title

      Chemistry and Physics of Lipids. (In press)

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Affinity capture of a mammalian DNA polymerase β by inhibitors immobilized to resins used in solid-phase organic synthesis.2005

    • Author(s)
      Kuramochi K, Haruyama Y, Takeuchi R, Sunoki T, Watanabe M, Oshige M, Kobayashi S, Sakaguchi K, Sugawara F
    • Journal Title

      Bioconjugate Chemistry. 16:97

      Pages: 97-104

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] The entrapment of kojic oleate in bilayer vesicles2005

    • Author(s)
      Manosroi A, Wongtrakul P, Manosroi J, Midorikawa U, Hanyu Y, Yuasa M, Sugawara F, Sakai H, Ahe M
    • Journal Title

      Int J Pharm. 298(1)

      Pages: 13-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.2005

    • Author(s)
      Mizushina Y, Kuramochi K, Ikawa H, Kuriyama I, Shimazaki N, Takemura M, Oshige M, Yoshida H, Koiwai O, Sugawara F, Kobayashi S, Sakaguchi K.
    • Journal Title

      Int. J. Mol. Med. 15

      Pages: 785-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.2004

    • Author(s)
      Miura K, Hanashima S, Takemura M, Yoshida H, Sugawara F, Sakaguchi K.
    • Journal Title

      Biochemistry 43

      Pages: 10669-10677

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Protective properties of neoechinulin A against SIN-1-induced neuronal cell death.2004

    • Author(s)
      Maruyama K, Ohuchi T, Yoshida K, Shibata Y, Sugawara F, Arai T
    • Journal Title

      J Biochem. (Tokyo) 36

      Pages: 81-87

    • NAID

      10016200897

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.2004

    • Author(s)
      Murakami-Nakai C, Maeda N, Yonezawa Y, Kuriyama I, Kamisuki S, Takahashi S, Sugawara F, Yoshida H, Sakaguchi K, Mizushina Y.
    • Journal Title

      Biochim.Biophys.Acta. 1674

      Pages: 193-199

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationships of untenone A and its derivatives for inhibition of DNA polymerases.2004

    • Author(s)
      Saito F, Takeuchi R, Kamino T, Kuramochi K, Sugawara F, Sakaguchi K, Kobayashi S.
    • Journal Title

      Bioorg. Med. Chem. Lett. 14

      Pages: 1975-1977

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Protective properties of neoechinulin A against SIN-1-induced neuronal cell death.2004

    • Author(s)
      Maruyama K, Ohuchi T, Yoshida K, Shibata Y, Sugawara F, Arai T.
    • Journal Title

      J.Biochem.(Tokyo) 36

      Pages: 81-87

    • NAID

      10016200897

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Structure-activity relationships of untenone A and its derivatives for inhibition of DNA polymerases2004

    • Author(s)
      Saito F, Takeuchi R, Kamino T, Kuramochi K, Sugawara F, Sakaguchi K, Kobayashi S
    • Journal Title

      Bioorg Med Chem Lett. 14

      Pages: 1975-1977

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationships of untenone A and its derivatives for inhibition of DNA polymerases2004

    • Author(s)
      Saito F, Takeuchi R, Kamino T, Kuramochi K, Sugawara F, Sakaguchi K, Kobayashi S.
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 1975-1977

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Inhibition of CD62L+ T-cell response in vitro via a novel sulfo-glycolipid, beta-SQAG9 liposome that binds to CD62L molecule on the cell surface.2004

    • Author(s)
      Yamamoto Y, Sahara H, Takenouchi M, Matsumoto Y, Imai A, Fujita T, Tamura Y, Takahashi N, Gasa S, Matsumoto K, Ohta K, Sugawara F, Sakaguchi K, Jimbow K, Sato N
    • Journal Title

      Cell Immuno 232(1-2)

      Pages: 105-115

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha2004

    • Author(s)
      Kamisuki S, Takahashi S, Mizushina Y, Sakaguchi K, Nakata T, Sugawara F
    • Journal Title

      Bioorg.Med.Chem 12

      Pages: 5355-5359

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin.2004

    • Author(s)
      Ogawa A, Murakami C, Kamisuki S, Kuriyama I, Yoshida H, Sugawara F, Mizushina Y.
    • Journal Title

      Bioorg. Med. Chem. Lett. 14

      Pages: 3539-3543

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Total synthesis of dehydroaltenusin2004

    • Author(s)
      Kamisuki S, Takahashi S, Mizushina Y, Hanashima S, Kuramochi K, Kobayashi S, Sakaguchi K, Nakata T, Sugawara F
    • Journal Title

      Tetrahedron 60

      Pages: 5695-5698

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of an immunosuppressant SQAG9 and determination of the binding peptide by T7 phase display.2004

    • Author(s)
      Yamazaki T, Aoki S, Ohta K, Hyuma S, Sakaguchi K, Sugawara F
    • Journal Title

      Bioorg Med Chem Lett. 14

      Pages: 4343-4346

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.2004

    • Author(s)
      Murakami-Nakai C, Maeda N, Yonezawa Y, Kuriyama I, Kamisuki S, Takahashi S, Sugawara F, Yoshida H, Sakaguchi K, Mizushina Y.
    • Journal Title

      Biochim.Biophys.Acta. 1674

      Pages: 193-199

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Total synthesis of dehydroaltenusin.2004

    • Author(s)
      Kamisuki S, Takahashi S, Mizushina Y, Hanashima S, Kuramochi K, Kobayashi S, Sakaguchi K, Nakata T, Sugawara F.
    • Journal Title

      Tetrahedron 60

      Pages: 5695-5695

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Taxol derivatives are selective inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Oshige M, Takenouchi M, Kato Y, Kamisuki S, Takeuchi T, Kuramochi K, Shiina I, Suenaga Y, Kawakita Y, Kuroda K, Sato N, Kobayashi S, Sugawara F, Sakaguchi K.
    • Journal Title

      Bioorg.Med.Chem. 12

      Pages: 2597-2601

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin2004

    • Author(s)
      Ogawa A, Murakami C, Kamisuki S, Kuriyama I, Yoshida H, Sugawara F, Mizushina Y.
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 3539-3543

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha2004

    • Author(s)
      Kamisuki S, Takahashi S, Mizushina Y, Sakaguchi K, Nakata T, Sugawara F
    • Journal Title

      Bloorg.Med.Chem 12

      Pages: 5355-5359

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Synthesis of an immunosuppressant SQAG9 and determination of the binding peptide by T7 phage display.2004

    • Author(s)
      Yamazaki T, Aoki S, Ohta K, Hyuma S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 4343-4346

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.2004

    • Author(s)
      Miura K, Hanashima S, Takemura M, Yoshida H, Sugawara F, Sakaguchi K.
    • Journal Title

      Biochemistry 43

      Pages: 10669-10677

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Taxol derivatives are selective inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Oshige M, Takenouchi M, Kato Y, Kamisuki S, Takeuchi T, Kuramochi K, Shiina I, Suenaga Y, Kawakita Y, Kuroda K, Sato N, Kobayashi S, Sugawara F, Sakaguchi K
    • Journal Title

      Bioorg Med Chem. 12

      Pages: 2597-2601

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Molecular design of cholesterols as inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Oshige M, Kuramochi K, Ohta K, Ogawa A, Kuriyama H, Sugawara F, Kobayashi S, Sakaguchi K
    • Journal Title

      J Med Chem. 47

      Pages: 4971-4974

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin reduces hepatic ischemia-reperfusion injury in rats.2004

    • Author(s)
      Tsuruma T, Sahara H, Takenouchi M, Yagihashi A, Iwayama Y, Shima H, Furuhata T, Torigoe T, Hanashima S, Yamazaki T, Sugawara F, Mizushina Y, Ohta K, Sakaguchi K, Sato N, Hirata K.
    • Journal Title

      Transplant Proc 36

      Pages: 1965-1969

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Molecular design of cholesterols as inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Oshige M, Kuramochi K, Ohta K, Ogawa A, Kuriyama H, Sugawara F, Kobayashi S, Sakaeuchi K
    • Journal Title

      J.Med.Chem. 47

      Pages: 4971-4974

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.2004

    • Author(s)
      Murakami-Nakai C, Maeda N, Yonezawa Y, Kuriyama I, Kamisuki S, Takahashi S, Sugawara F, Yoshida H, Sakaguchi K, Mizushina Y.
    • Journal Title

      Biochim. Biophys. Acta. 1674

      Pages: 193-199

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha2004

    • Author(s)
      Kamisuki S, Takahashi S, Mizushina Y, Sakaguchi K, Nakata T, Sugawara F
    • Journal Title

      Bioorg Med Chem 12

      Pages: 5355-5359

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.2004

    • Author(s)
      Kuramochi K, Mizushina Y, Nagata S, Sugawara F, Sakaguchi K, Kobayashi S
    • Journal Title

      Bioorg Med Chem. 12

      Pages: 1983-1989

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin2004

    • Author(s)
      Ogawa A, Murakami C, Kamisuki S, Kuriyama I, Yoshida H, Sugawara F, Mizushina Y.
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 3539-3543

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin reduces hepatic ischemia-reperfusion injury in rats.2004

    • Author(s)
      Tsuruma T, Sahara H, Takenouchi M, Yagihashi A, Iwayama Y, Shima H, Furuhata T, Torigoe T, Hanashima S, Yamazaki T, Sugawara F, Mizushina Y, Ohta K, Sakaguchi K, Sato N, Hirata K.
    • Journal Title

      Transplant Proc 36

      Pages: 1965-1969

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthetic sulfonolipids deduced from sulfonoquinovosyldiacylglycerols of sea urchin reduces hepatic ischemia-reperfusion injury in rats.2004

    • Author(s)
      Tsuruma T, Sahara H, Takenouchi M, Yagihashi A, Iwayama Y, Shima H, Furuhata T, Torigoe T, Hanashima S, Yamazaki T, Sugawara F, Mizushina Y, Ohta K, Sakaguchi K, Sato N, Hirata K.
    • Journal Title

      Transplant. Proc. 36

      Pages: 1965-1969

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Protective properties of neoechinulin A against SIN-1-induced neuronal cell death.2004

    • Author(s)
      Maruyama K, Ohuchi T, Yoshida K, Shibata Y, Sugawara F, Arai T.
    • Journal Title

      J.Biochem.(Tokyo) 36

      Pages: 81-87

    • NAID

      10016200897

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.2004

    • Author(s)
      Kuramochi K, Mizushina Y, Nagata S, Sugawara F, Sakaguchi K, Kobayashi S.
    • Journal Title

      Bioorg.Med.Chem. 12

      Pages: 1983-1989

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.2004

    • Author(s)
      Miura K, Hanashima S, Takemura M, Yoshida H, Sugawara F, Sakaguchi K
    • Journal Title

      Biochemistry 43

      Pages: 10669-10677

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.2004

    • Author(s)
      Miura K, Hanashima S, Takemura M, Yoshida H, Sugawara F, Sakaguchi K.
    • Journal Title

      Biochem. 43

      Pages: 10669-10677

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin2004

    • Author(s)
      Ogawa A, Murakami C, Kamisuki S, Kuriyama I, Yoshida H, Sugawara F, Mizushina Y
    • Journal Title

      Bioorg Med Chem Lett. 14

      Pages: 3539-3543

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Taxol derivatives are selective inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Oshige M, Takenouchi M, Kato Y, Kamisuki S, Takeuchi T, Kuramochi K, Shiina I, Suenaga Y, Kawakita Y, Kuroda K, Sato N, Kobayashi S, Sugawara F, Sakaguchi K.
    • Journal Title

      Bioorg. Med. Chem. 12

      Pages: 2597-2601

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Molecular design of cholesterols as inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Ohshige M, Kuramochi K, Ohta K, Ogawa A, Kuriyama H, Sugawara F, Kobayashi S, Sakaguchi K.
    • Journal Title

      J. Med. Chem. 47

      Pages: 4971-4974

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Taxol derivatives are selective inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Oshige M, Takenouchi M, Kato Y, Kamisuki S, Takeuchi T, Kuramochi K, Shiina I, Suenaga Y, Kawakita Y, Kuroda K, Sato N, Kobayashi S, Sugawara F, Sakaguchi K.
    • Journal Title

      Bioorg.Med.Chem. 12

      Pages: 2597-2601

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.2004

    • Author(s)
      Kamisuki S, Takahashi S, Mizushina Y, Sakaguchi K, Nakata T, Sugawara F.
    • Journal Title

      Bioorg. Med. Chem. 12

      Pages: 5355-5359

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Inhibition of CD62L(+) T-cell response in vitro via a novel sulfo-glycolipid, beta-SQAG9 liposome that binds to CD62L molecule on the cell surface.2004

    • Author(s)
      Yamamoto Y, Sahara H, Takenouchi M, Matsumoto Y, Imai A, Fujita T, Tamura Y, Takahashi N, Gasa S, Matsumoto K, Ohta K, Sugawara F, Sakaguchi K, Jimbow K, Sato N.
    • Journal Title

      Cell Immunol. 232

      Pages: 105-115

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationships of untenone A and its derivatives for inhibition of DNA polymerases2004

    • Author(s)
      Saito F, Takeuchi R, Kamino T, Kuramochi K, Sugawara F, Sakaguchi K, Kobayashi S.
    • Journal Title

      Bloorg.Med.Chem.Lett. 14

      Pages: 1975-1977

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Molecular design of cholesterols as inhibitors of DNA polymerase alpha.2004

    • Author(s)
      Oshige M, Kuramochi K, Ohta K, Ogawa A, Kuriyama H, Sugawara F, Kobayashi S, Sakaguchi K
    • Journal Title

      J.Med.Chem. 47

      Pages: 4971-4974

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Design of vesicles of 1,2-di-O-acyl-3-O-(beta-D-sulfoquinovosyl)-glyceride bearing two stearic acids (beta-SQDG-C(18)), a novel immunosuppressive drug.2004

    • Author(s)
      Matsumoto K, Takenouchi M, Ohta K, Ohta Y, Imura T, Oshige M, Yamamoto Y, Sahara H, Sakai H, Abe M, Sugawara F, Sato N, Sakaguchi K.
    • Journal Title

      Biochem. Pharmacol. 68

      Pages: 2379-2386

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] A tublin-based quantitative assay for Taxol (Paclitaxel) with enzyme channeling sensing.2004

    • Author(s)
      Suye S, Nakamoto D, Hori T, Sugawara F, Mulchandani A
    • Journal Title

      Electroanalysis 16

      Pages: 688-690

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of an immunosuppressant SQAG9 and determination of the binding peptide by T7 phage display.2004

    • Author(s)
      Yamazaki T, Aoki S, Ohta K, Haruyama S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioorg. Med. Chem. Lett. 14

      Pages: 4343-4346

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.2004

    • Author(s)
      Murakami-Nakai C, Maeda N, Yonezawa Y, Kuriyama I, Kamisuki S, Takahashi S, Sugawara F, Yoshida H, Sakaguchi K, Mizushina Y
    • Journal Title

      Biochim. Biophys. Acta. 1674

      Pages: 193-199

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of the proposed structure of plakevulin A : revised structure of plakevulin A.2004

    • Author(s)
      Saito F, Takeuchi R, Kamino T, Kuramochi K, Sugawara F, Sakaguchi K, Kobayashi S, Tsuda M, Kobayashi J.
    • Journal Title

      Tetrahedron Lett. 45

      Pages: 8069-8071

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin reduces hepatic ischemia-reperfusion injury in rats.2004

    • Author(s)
      Tsuruma T, Sahara H, Takenouchi M, Yagihashi A, Iwayama Y, Shima H, Furuhata T, Torigoe T, Hanashima S, Yamazaki T, Sugawara F, Mizushina Y, Ohta K, Sakaguchi K, Sato N, Hirata K
    • Journal Title

      Transplant Proc 36

      Pages: 1965-1969

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Protective properties of neoechinulin A against SIN-1-induced neuronal cell death.2004

    • Author(s)
      Maruyama K, Ohuchi T, Yoshida K, Shibata Y, Sugawara F, Arai T.
    • Journal Title

      J. Biochem. (Tokyo). 36

      Pages: 81-87

    • NAID

      10016200897

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of the proposed structure of plakevulin A : revised structure of plakevulin A.2004

    • Author(s)
      Saito F, Takeuchi R, Kamino T, Kuramochi K, Sugawara F, Sakaguchi K, Kobayashi S, Tsuda M, Kobayashi J
    • Journal Title

      Tetrahedron Lett. 45

      Pages: 8069-8071

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Design of vesicles of 1,2-di-O-acyl-3-O-(beta-D-sulfoquinovosyl)-glyceride bearing two stearic acids (beta-SQDG-C(18)), a novel immunosuppressive drug.2004

    • Author(s)
      Matsumoto K, Takenouchi M, Ohta K, Ohta Y, Imura T, Oshige M, Yamamoto Y, Sahara H, Sakai H, Abe M, Sugawara F, Sato N, Sakaguchi K
    • Journal Title

      Biochem Pharmacol. 68

      Pages: 2379-2386

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.2004

    • Author(s)
      Kuramochi K, Mizushina Y, Nagata S, Sugawara F, Sakaguchi K, Kobayashi S.
    • Journal Title

      Bioorg. Med. Chem. 12

      Pages: 1983-1989

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Synthesis of an immunosuppressant SQAG9 and determination of the binding peptide by T7 phage display.2004

    • Author(s)
      Yamazaki T, Aoki S, Ohta K, Hyuma S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 4343-4346

    • Data Source
      KAKENHI-PROJECT-16310155
  • [Journal Article] Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.2004

    • Author(s)
      Kuramochi K, Mizushina Y, Nagata S, Sugawara F, Sakaguchi K, Kobayashi S.
    • Journal Title

      Bloorg.Med.Chem. 12

      Pages: 1983-1989

    • Data Source
      KAKENHI-PROJECT-15651101
  • [Journal Article] Podophyllotoxin directly binds a hinge domain in E2 of HPV and inhibits an E2/E7 interaction in vitro.

    • Author(s)
      Saitoh T, Kuramochi K, Imai T, Takata KI, Takehara M, Kobayashi S, Sakaguchi K, Sugawara F.
    • Journal Title

      Bioorg Med Chem 16(10)

      Pages: 5815-25

    • Data Source
      KAKENHI-PROJECT-19380066
  • [Patent] 新規なスルホン酸化糖誘導およびその医薬としての使用2009

    • Inventor(s)
      太田慶祐三浦雅彦坂口謙吾菅原二三男佐藤昇志佐原弘益高橋延昭森陽子山崎隆之正木和好村田博
    • Industrial Property Rights Holder
      東洋水産株式会社
    • Filing Date
      2009-01-19
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Patent] 腫瘍滞留性を有する化合物2009

    • Inventor(s)
      太田慶祐三浦雅彦坂口謙吾菅原二三男村田博石間正浩
    • Industrial Property Rights Holder
      東洋水産株式会社
    • Filing Date
      2009-01-20
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Patent] シクロスポリンA結合タンパク質2008

    • Inventor(s)
      佐原弘益森陽子高橋延昭佐藤昇志菅原二三男坂口謙吾諸橋謙吾岩端一樹渡士幸一下遠野邦忠菊地浩吉傅亘宮下広樹
    • Industrial Property Rights Holder
      北海道公立大學学校法人札幌医科大学, 学校法人東京理科大学, 国立大学法人京都大学, 株式会社イムノ・ダイアグノスティク・ラボラトリー
    • Filing Date
      2008-08-22
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Patent] RADIOSENSITIZER2007

    • Inventor(s)
      菅原二三男, 山崎隆
    • Industrial Property Rights Holder
      東洋水産(株)
    • Acquisition Date
      2007-01-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Patent] 新規なスルホン酸化誘導体およびその医薬としての使用2007

    • Inventor(s)
      太田慶祐、三浦雅彦、坂口健吾、菅原二三男、佐藤昇志、佐原広益、高橋延昭、森陽子、山崎隆之、正木和好
    • Industrial Property Rights Holder
      東京医科歯科大学, 札幌医科大学、東洋水産(株)
    • Industrial Property Number
      2007-190120
    • Filing Date
      2007-07-20
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Patent] 新規な放射線治療増感剤2004

    • Inventor(s)
      菅原 二三男, 山崎 隆之 他
    • Industrial Property Rights Holder
      東京理科大学
    • Filing Date
      2004-06-24
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Patent] 新規イソクロマノン化合物とその行為丸剤への利用2004

    • Inventor(s)
      菅原 二三男, 水品 善之 他
    • Industrial Property Rights Holder
      東京理科大学
    • Filing Date
      2004-04-19
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Patent] 新規な放射線治療増感剤.2004

    • Inventor(s)
      菅原二三男, 山崎隆
    • Industrial Property Rights Holder
      東京理科大学
    • Filing Date
      2004-06-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Patent] Administration of a sulfopyranosylacylglycerol to treat certain cancer2004

    • Inventor(s)
      菅原二三男, 山崎隆
    • Industrial Property Rights Holder
      東洋水産(株)
    • Acquisition Date
      2004-08-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Patent] 新規な放射線治療増感剤2004

    • Inventor(s)
      菅原 二三男, 山崎 隆之 他
    • Industrial Property Rights Holder
      東京理科大学
    • Filing Date
      2004-06-24
    • Data Source
      KAKENHI-PROJECT-15651101
  • [Patent] 新規イソクロマノン化合物とその行為丸剤への利用2004

    • Inventor(s)
      菅原 二三男, 水品 善之 他
    • Industrial Property Rights Holder
      東京理科大学
    • Filing Date
      2004-04-19
    • Data Source
      KAKENHI-PROJECT-15651101
  • [Patent] 新規イソクロマノン化合物とその行為丸剤への利用2004

    • Inventor(s)
      菅原二三男, 水品善
    • Industrial Property Rights Holder
      東京理科大学
    • Filing Date
      2004-04-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310155
  • [Patent] Administration of a sulfopyranosylacylglycerol to treat certain cancer2004

    • Inventor(s)
      菅原 二三男, 山崎 隆之 他
    • Industrial Property Rights Holder
      東洋水産(株)
    • Acquisition Date
      2004-08-03
    • Data Source
      KAKENHI-PROJECT-15651101
  • [Presentation] 神経保護物質ネオエキヌリンAの結合タンパク質の同定2018

    • Author(s)
      紙透伸治、姫野なつみ、鶴川幸音、草柳友恵、竹野正洋、鎌倉高志、倉持幸司、菅原二三男
    • Organizer
      日本農芸化学会2018年度大会
    • Data Source
      KAKENHI-PROJECT-15K01808
  • [Presentation] NOVEL ANTICANCER AGENT, SQAP, BINDS TO FOCAL ADHESION KINASE AND MODULATE ITS ACTIVITY2015

    • Author(s)
      Jesús Izaguirre-Carbonell, Hirofumi Kawakubo, Hiroshi Murata, Keisuke Ohta, Tomoe Kusayanagi, Senko Tsukuda, Takeshi Hirakawa, Kazuki Iwabata, Yoshihiro Kanai, Sachihiro Matsunaga, Shinji Kamisuki, Kengo Sakaguchi and Fumio Sugawara
    • Organizer
      2015 Annual Meeting of the ASP
    • Place of Presentation
      Copper Mountain, CO, USA
    • Year and Date
      2015-07-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07419
  • [Presentation] 線虫ガレクチンLEC-6による糖鎖認識機構解明のための分子プローブの合成及びその評価2010

    • Author(s)
      西山和沙, 山田篤, 草柳友恵, 松本勇記, 高草木洋一, 菅原二三男, 坂口謙吾, 小林進, 武内智春, 笠井献一, 夏苅英昭, 高橋秀依
    • Organizer
      日本薬学会第130年会
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] エポラクタエン及び誘導体の化学と生物:全合成から作用機構解析2010

    • Author(s)
      倉持幸司, 椿一典, 水品善之, 菅原二三男, 池北雅彦, 小林進
    • Organizer
      第4回連携大学院セミナー京都「先端バイオイメージングと基盤技術」
    • Year and Date
      2010-01-18
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Sinthesis of Natural Products (2): Bioactive Compounds.2009

    • Author(s)
      Hiroaki Ishii, Kyohei Shimizu, Satomi Shimura, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] エポラクタエン及び誘導体のチオール反応性2009

    • Author(s)
      倉持幸司, 椿一典, 水品善之, 菅原二三男, 池北雅彦, 小林進
    • Organizer
      日本農芸化学会関西支部例会
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 海洋天然物SQAGによるDNA polymerase lambda の阻害様式の解明2009

    • Author(s)
      高草木香織, 太田慶祐, 高草木洋一, 青木仁子, 菅原二三男, 坂口謙吾
    • Organizer
      日本ケミカルバイオロジー学会第4回年会
    • Place of Presentation
      神戸市産業振興センター
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] YファミリーDNAポリメラーゼ選択的阻害剤:Penicilliol A, Penicilliol B2009

    • Author(s)
      水品善之, 木村拓馬, 竹内倫文, 米澤裕子, 大橋英治, 大森治夫, 益谷央豪, 花岡文雄, 吉田弘美, 菅原二三男, 坂口謙吾
    • Organizer
      第32回日本分子生物学会
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] X-family DNAポリメラーゼによる生物多様性の調節2009

    • Author(s)
      小寺啓文, 武内亮, 半澤直人, 内山幸伸, 美和秀胤, 菅原二三男, 坂口謙吾
    • Organizer
      第11回日本進化学会大会
    • Year and Date
      2009-09-02
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] QCM-phage display : Identification of doxorubicin-binding protein(part III)2009

    • Author(s)
      草柳友恵, 高草木洋一, 武内智春, 坂口謙吾, 菅原二三男
    • Organizer
      The 50th Anniversary Meeting of the American Society of Pharmacognosy
    • Place of Presentation
      Honolulu, HI
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Synthesis of Natural Products (1): The Radio Sensitizer SQ series.2009

    • Author(s)
      Hiroshi Murata, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Isolation of Natural Products (1)2009

    • Author(s)
      Takuma Kimura, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Synthesis of Natural Products(1) : The Radio Sensitizer SQ series.2009

    • Author(s)
      Hiroshi Murata, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Place of Presentation
      東京・ホテルエドモント
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] QCM-phage display: Identification of doxorubicin-binding protein (part III)2009

    • Author(s)
      Kusayanagi T, Takakusagi Y, Takeuchi T, Sakaguchi K, Sugawara F
    • Organizer
      The 50th Anniversary Meeting of the American Society of Pharmacognosy
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Camptothecins : Inhibition of the E-prostanoid receptor subtype 1(EP1)signaling pathways and its' mechanistic aspects2009

    • Author(s)
      Takakusagi Y, Manita D, Okado M, Nakayama M, Takakusagi K, Sugawara F, Sakaguchi K
    • Organizer
      The 50th Anniversary Meeting of the American Society of Pharmacognosy
    • Place of Presentation
      Honolulu, HI
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] カバノアナタケから同定された新規化合物DDTCTの細胞増殖抑制効果2009

    • Author(s)
      望月万里, 森田明典, 羽染芳宗, 井田紀子, 村田寛, 船津修, 菅原二三男, 池北雅彦
    • Organizer
      第82回日本生化学会大会
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] クルクミン誘導体の抗炎症作用2009

    • Author(s)
      西田真之, 吉田優, 東健, 福留啓志, 清水恭平, 竹内倫文, 大澤俊彦, 菅原二三男, 水品義之, 吉田弘美
    • Organizer
      日本農芸化学会2009年度(平成21年度)大会
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Isolation of Natural Products (2)2009

    • Author(s)
      Yoshihiro Sato, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 PD法による低分子化合物とタンパク質の相互作用の検出: QCM装置とRELICサーバーの利用がもたらす実用性と可能性2009

    • Author(s)
      高草木洋一, 高草木香織, 菅原二三男, 坂口謙吾
    • Organizer
      第32回日本分子生物学会
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] ニガウリ由来のmonoacylgalactosyl diacylglycerol (MGDG)のDNAポリメラーゼ阻害活性とヒト癌増殖抑制活性2009

    • Author(s)
      松井由樹, 羽田尚彦, 佐藤義大, 山口素弘, 竹内倫文, 坂口謙吾, 菅原二三男, 水品義之, 吉田弘美
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡・マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法を用いたタンパク質問相互作用阻害剤の探索法の改良2009

    • Author(s)
      齊藤雄己, 真仁田大輔, 菅原二三男
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡・マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 含硫糖脂質SQAGのhVEGF165結合領域の同定及び結合様式の解明2009

    • Author(s)
      高草木香織, 高草木洋一, 松本勇記, 鷹見美穂子, 井田紀子, 青木仁子, 村田寛, 太田慶祐, 菅原二三男, 坂口謙吾
    • Organizer
      第32回日本分子生物学会
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法を用いたタンパク質間相互作用阻害剤の探索法の改良2009

    • Author(s)
      齊藤雄己, 真仁田大輔, 菅原二三男
    • Organizer
      日本農芸化学会2009年度(平成21年度)大会
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 浜辺に生息する苔に寄生する真菌(Penicillium deleae)ユリアの新規物質peniciliol AおよびBの生理活性2009

    • Author(s)
      水品義之, 木村拓馬, 竹内倫文, 菅原二三男
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡・マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Self-assembled monolayer (SAM) of small organic molecule for efficient random-peptide phage display selection using a cuvette type quartz-crystal microbalance2009

    • Author(s)
      Takakusagi Y, Suzuki A, Sugawara F, Kobayashi S, Sakaguchi K
    • Organizer
      (QCM) device ICCE-17
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Camptothecins : Inhibition of the E-prostanoid receptor subtype 12009

    • Author(s)
      Takakusagi Y, Manita D, Okado M, Nakayama M, Takakusagi K, Sugawara F, Sakaguchi K
    • Organizer
      (EP1) signaling pathways and its' mechanistic aspects The 50th Anniversary Meeting of the American Society of Pharmacognosy
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Sinthesis of Natural Products(2) : Bioactive Compounds.2009

    • Author(s)
      Hiroaki Ishii, Kyohei Shimizu, Satomi Shimura, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Place of Presentation
      東京・ホテルエドモント
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] クルクミン誘導体の抗炎症作用2009

    • Author(s)
      西田真之, 古田優, 東健, 福留啓志, 清水恭平, 竹内倫文, 大澤俊彦, 菅原二三男, 水品義之, 吉田弘美
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡・マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] トリマンノース由来の分子プローブの合成とQCM-PD-SAM法を用いた結合ペプチドの同定2009

    • Author(s)
      西山和沙, 高草木洋一, 草柳友恵, 松本勇記, 羽生紫織, 倉持幸司, 菅原二三男, 坂口謙吾, 高橋秀依, 夏苅英昭, 小林進
    • Organizer
      日本薬学会第129年会
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法を用いて同定したアンジオモチンとロキシスロマイシンの相互作用の検証2009

    • Author(s)
      鈴木愛こ, 高草木洋一, 渡辺まどか, 松本勇記, 戸井崎絢, 鈴木孝洋, 菅原二三男, 小林進, 坂口謙吾
    • Organizer
      第32回日本分子生物学会
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Developement of Phage Display with Quartz Crystal Microbalance Method.2009

    • Author(s)
      Tomoe Kusayanagi, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Antitumor Antibiotic Fostriecin Targets Cystein-269 of the Protein Phosphatase 2A Catalitic Subunit in Mammailan Cells with a Covalent Bond.2009

    • Author(s)
      Toshifumi Takeuchi, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] New Screening Methods for Protein-Protein Interaction Inhibitors Based on FRET and Phage Display.2009

    • Author(s)
      Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] A Facile Method to inhibit Protein-Protein Interactions with Phage Display Method.2009

    • Author(s)
      Takeki Saitoh, Fumio Sugawara
    • Organizer
      3rd Tokyo Uiniversity of Science Interanational Collaboration Workshop
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Self-assembled monolayer(SAM)of small organic molecule for efficient random-peptide phage display selection using a cuvette type quartz-crystal microbalance(QCM)device2009

    • Author(s)
      高草木洋一, 鈴木愛こ, 菅原二三男, 小林進, 坂口謙吾
    • Organizer
      ICCE-17
    • Place of Presentation
      Honolulu, HI
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 浜辺に生息する苔に寄生する真菌(Penicillium deleae)ユリアの新規物質peniciliol AおよびBの生理活性2009

    • Author(s)
      水品義之, 木村拓馬, 竹内倫文, 菅原二三男
    • Organizer
      日本農芸化学会2009年度(平成21年度)大会
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] ニガウリ由来のmonoacylgalactosyl diacylglycerol (MGDG)のDNAポリメラーゼ阻害活性とヒト癌増殖抑制活性2009

    • Author(s)
      松井由樹, 羽田尚彦, 佐藤義大, 山口素弘, 竹内倫文, 坂口謙吾, 菅原二三男, 水品義之, 吉田弘美
    • Organizer
      日本農芸化学会2009年度(平成21年度)大会
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 海洋天然物SQAGによるDNA polymerase lambdaの阻害様式の解明2009

    • Author(s)
      高草木香織, 太田慶祐, 高草木洋一, 青木仁子, 菅原二三男, 坂口謙吾
    • Organizer
      日本ケミカルバイオロジー学会第4回年会
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 多価不飽和脂肪酸はIMPデヒドロゲナーゼを阻害する2008

    • Author(s)
      水品 善之、矢中 規之、Han, Yunkyung、竹内 倫文、石丸 千里、菅原 二三男、吉田 弘美、加藤 範久
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名城大学
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] クルクミンとその誘導体による炎症抑制効果2008

    • Author(s)
      西田真之, 吉田優, 東健, 福留啓志, 竹内倫文, 倉持幸司, 菅原二三男, 坂口謙吾, 吉田弘美, 水品善之
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] トリマンノース由来の分子プローブの合成とQCM-PD法による結合ペプチドの探索2008

    • Author(s)
      西山和沙, 草柳友恵, 高草木洋一, 倉持幸司, 菅原二三男, 坂口謙吾, 高橋秀依, 夏苅英昭, 小林進
    • Organizer
      日本薬学会128年会
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 固相合成用樹脂を利用した結合タンパク質探索2008

    • Author(s)
      榎本好宏, 倉持幸司, 宮野友香, 石一智, 高草木洋一, 斉藤雄己, 小林進, 坂口謙吾, 菅原二三男
    • Organizer
      先端科学セミナー京都 ケミカルバイオロジーシンポジウム
    • Place of Presentation
      京都府立大学
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 ファージディスプレイ法によるポドフィロトキシンの新規結合タンパク質の探索と同定2008

    • Author(s)
      斉藤 雄己、倉持 幸司、今井 孝彦、高田 慶一、菅原 二三男
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名城大学
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 固相合成用樹脂を利用した結合タンパク質探索2008

    • Author(s)
      榎本好宏, 倉持幸司, 宮野友香, 石一智, 高草木洋一, 斉藤雄己, 小林進, 坂口謙吾, 菅原二三男
    • Organizer
      先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 抗腫瘍活性物質カンプトテシンの新規作用標的タンパク質の探索2008

    • Author(s)
      真仁田大輔, 高草木洋一, 倉持幸司, 菅原二三男
    • Organizer
      先端科学セミナー京都 ケミカルバイオロジーシンポジウム
    • Place of Presentation
      京都府立大学
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法を用いたBrz-2001とチトクロムP450 DWF4の結合解析2008

    • Author(s)
      真仁田大輔, 草柳友恵, 高草本洋一, 倉持幸司, 菅原二三男
    • Organizer
      日本ケミカルバイオロジー研究会第3回年会
    • Place of Presentation
      東京学術総合センター
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] QCM T7 ファージディスプレイ法 : 新規ドキソルビシン結合タンパク質の探索(第二報)2008

    • Author(s)
      草柳友恵, 倉持幸司, 高草木洋一, 菅原二三男
    • Organizer
      先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Place of Presentation
      京都府立大学
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] カバノアナタケから同定されたDDTCTの細胞増殖抑制効果2008

    • Author(s)
      望月万里, 森田明典, 羽染芳宗, 井田紀子, 村田寛, 船津修, 菅原二三男, 池北雅彦
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 医薬小分子結合タンパク質の同定を目的としたワンサイクルT7ファージディスプレイ法の研究2008

    • Author(s)
      草柳友恵, 高木真奈美, 真仁田大輔, 岩切佳那子, 倉持幸司, 高草木洋一, 中崎敦夫, 小林進, 坂口謙吾, 菅原二三男
    • Organizer
      日本ケミカルバイオロジー研究会第3回年会
    • Year and Date
      2008-05-19
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法によるドキソルビシン標的タンパク質の探索および酵母を用いた生物活性評価法の研究2008

    • Author(s)
      真仁田大輔, 小柳邦生, 高橋徳行, 今井孝彦, 石一智, 倉持幸司, 菅原二三男
    • Organizer
      日本農芸化学会2008年度大会
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 phage display法による抗腫瘍性抗生物質PD 113,271結合タンパク質の探索2008

    • Author(s)
      今井 孝彦、竹内 倫文、石 一智、斉藤 雄己、倉持 幸司、菅原 二三男
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名城大学
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] QCM T7 ファージディスプレイ法 : 新規ドキソルビシン結合タンパク質の探索(第一報)2008

    • Author(s)
      草柳友恵, 真仁田大輔, 岩切佳那子, 倉持幸司, 高草木洋一, 中崎敦夫, 小林進, 坂口謙吾, 菅原二三男
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] ワンステップT7ファージディスプレイ法による医薬小分子の結合タンパク質の同定2008

    • Author(s)
      草柳友恵, 高木真奈美1, 真仁田大輔, 岩切佳那子, 倉持幸司, 高草木洋一, 中崎敦夫, 小林進, 坂口謙吾, 菅原二三男
    • Organizer
      日本農芸化学会2008年度大会
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] クルクミン誘導体の抗炎症作用の解析2008

    • Author(s)
      西田 真之、吉田 優、東 健、大澤 俊彦、福留 啓志、竹内 倫文、倉持 幸司、菅原 二三男、水品 善之、吉田 弘美
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名城大学
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 phage display 法を用いたロキシスロマイシン結合タンパク質の探索2008

    • Author(s)
      鈴木愛子, 高草木洋一, 渡邊まどか, 松本勇記, 菅原二三男, 坂口謙吾
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 抗腫瘍活性物質カンプトテシンの新規作用標的タンパク質の探索2008

    • Author(s)
      真仁田大輔, 高草木洋一, 倉持幸司, 菅原二三男
    • Organizer
      先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 phage display 法を用いたPFOS結合タンパク質の探索2008

    • Author(s)
      岡戸真実, 宮野友香, 崎元一平, 志村聡美, 草柳友恵, 武内亮, 高草本香織, 松本勇記, 中崎敦夫, 竹内倫文, 倉持幸司, 高草木洋一, 太田慶祐, 三浦雅彦, 小林進, 菅原二三男, 坂口謙吾
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] クルクミン誘導体の抗炎症作用の解析2008

    • Author(s)
      西田真之, 吉田優, 東健, 大澤俊彦, 福留啓志, 竹内倫文, 倉持幸司, 菅原二三男, 水品善之, 吉田弘美
    • Organizer
      日本農芸化学会2008年度大会
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] QCM T7ファージディスプレイ法:新規ドキソルビシン結合タンパク質の探索2008

    • Author(s)
      草柳友恵, 倉持幸司, 高草木洋一, 菅原二三男
    • Organizer
      (第二報)先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] ワンステップT7ファージディスプレイ法による医薬小分子の結合タンパク質の同定2008

    • Author(s)
      草柳 友恵、高木 真奈美、真仁田 大輔、岩切 佳那子、倉持 幸司、高草木 洋一、中崎 敦夫、小林 進、坂口 謙吾、菅原 二三男
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名城大学
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 多価不飽和脂肪酸はIMPデヒドロゲナーゼを阻害する2008

    • Author(s)
      水品善之, 矢中規之, Han, Yunkyung, 竹内倫文, 石丸千里, 菅原二三男, 吉田弘美, 加藤範久
    • Organizer
      日本農芸化学会2008年度大会
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] CBP501によるG2チェックポイント阻害作用の詳細についての研究2008

    • Author(s)
      松本勇記, 高草木洋一, 新藤陽介, 高草木香織, 小谷野祐希, 佐藤仁志, 河邊拓己, 菅原二三男, 坂口謙吾
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] QCM T7ファージディスプレイ法:新規ドキソルビシン結合タンパク質の探索2008

    • Author(s)
      草柳友恵, 真仁田大輔, 岩切佳那子, 倉持幸司, 高草木洋一, 中崎敦夫, 小林進, 坂口謙吾, 菅原二三男
    • Organizer
      (第一報)第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 糖認識機能解明のための分子プローブの合成2008

    • Author(s)
      西山和沙, 草柳友恵, 高草木洋一, 倉持幸司, 菅原二三男, 坂口謙吾, 武内智春, 笠井献一, 高橋秀依, 夏苅英昭, 小林進
    • Organizer
      第55回有機合成化学協会関東支部シンポジウム
    • Year and Date
      2008-05-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法によるポドフィロトキシンの新規結合タンパク質の探索と同定2008

    • Author(s)
      斉藤雄己, 倉持幸司, 今井孝彦, 高田慶一, 菅原二三男
    • Organizer
      日本農芸化学会2008年度大会
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 phage display法による抗腫瘍性抗生物質PD 113, 271結合タンパク質の探索2008

    • Author(s)
      今井孝彦, 竹内倫文, 石一智, 斉藤雄己, 倉持幸司, 菅原二三男
    • Organizer
      日本農芸化学会2008年度大会
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法を用いたBrz-2001とチトクロムP450 DWF4の結合解析2008

    • Author(s)
      真仁田大輔, 草柳友恵, 高草木洋一, 倉持幸司, 菅原二三男
    • Organizer
      日本ケミカルバイオロジー研究会第3回年会
    • Year and Date
      2008-05-19
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 phage display法を用いたPFOS結合タンパク質の探索2008

    • Author(s)
      岡戸真実, 宮野友香, 崎元一平, 志村聡美, 草柳友恵, 武内亮, 高草木香織, 松本勇記, 中崎敦夫, 竹内倫文, 倉持幸司, 高草木洋一, 太田慶祐, 三浦雅彦, 小林進, 菅原二三男, 坂口謙吾
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 糖鎖認識機能解明のための分子プローブの合成2008

    • Author(s)
      西山和沙, 草柳友恵, 松本勇記, 高草木洋一, 倉持幸司, 菅原二三男, 坂口謙吾, 高橋秀依, 夏苅英昭, 小林進
    • Organizer
      反応と合成の進歩シンポジウム
    • Year and Date
      2008-11-04
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法によるドキソルビシン標的タンパク質の探索および酵母を用いた生物活性評価法の研究2008

    • Author(s)
      真仁田 大輔、小柳 邦生、高橋 徳行、今井 孝彦、石 一智、倉持 幸司、菅原 二三男
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名城大学
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 糖認識機能解明のための分子プローブの合成2008

    • Author(s)
      西山和沙, 草柳友恵, 高草木洋一, 倉持幸司, 菅原二三男, 坂口謙吾, 武内智春, 笠井献一, 高橋秀依, 夏苅英昭, 小林 進
    • Organizer
      第55回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      野田市・東京理科大学
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] キイロショウジョウバエによる医薬標的分子の評価2008

    • Author(s)
      真仁田大輔, 高草木洋一, 松本勇記, 高田和徳, 坂口謙吾, 菅原二三男
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法を用いたリダイフェンBの新規標的タンパク質の探索2008

    • Author(s)
      九十田千子, 高草木洋一, 今井孝彦, 椎名勇, 坂口謙吾, 池北雅彦, 菅原二三男
    • Organizer
      先端科学セミナー京都 ケミカルバイオロジーシンポジウム
    • Place of Presentation
      京都府立大学
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Target Identification: Affinithy Selection and Phage Display2008

    • Author(s)
      Fumio Sugawara
    • Organizer
      Zhang Synposium for Drug Discovery.
    • Place of Presentation
      Antigua
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法を用いたリダイフェンBの新規標的タンパク質の探索2008

    • Author(s)
      九十田千子, 高草木洋一, 今井孝彦, 椎名勇, 坂口謙吾, 池北雅彦, 菅原二三男
    • Organizer
      先端科学セミナー京都ケミカルバイオロジーシンポジウム
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 phage display法を用いたロキシスロマイシン結合タンパク質の探索2008

    • Author(s)
      鈴木愛こ, 高草木洋一, 渡邊まどか, 松本勇記, 菅原二三男, 坂口謙吾
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法によるメトトレキサートの新規結合タンパク質の探索2007

    • Author(s)
      黒岩祐貴, 高草木洋一, 倉持幸司, 今井孝彦, 伊藤一明, 吉田充輝, 菅原二三男
    • Organizer
      日本ケミカルバイオロジー研究会
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 有機合成用樹脂をアフィニティー担体として利用したファージディスプレイ法2007

    • Author(s)
      榎本好宏, 倉持幸司, 一智, 新井威史, 菅原二三男
    • Organizer
      日本農芸化学会2007年度大会
    • Year and Date
      2007-03-25
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Down regulation of Tie-2 gene in vivo by novel anti-tumor agent SQAG targeting antiangionesis2007

    • Author(s)
      Yoko Mori, Hiroeki Sahara, Kayo Matsumoto, Nobuaki Takahashi, Takayuki Yamazaki, Keisuke Ohta, Satoko Aoki, Masahiko Miura, Fumio Sugawara, Kengo Sakaguchi, Noriyuki Sato
    • Organizer
      第66回日本癌学会学術総会
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] EFFECTS OF DNA POLYMERASE ALPHA POISON DEHYDROALTENUSIN ON THE FISSION YEAST SCHIZOSACCHAROMYCES POMBE BMB20072007

    • Author(s)
      栗山磯子, 紙透伸治, 菅原二三男, 吉田弘美, 水品善之, 野口英史
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] カバノアナタケから同定された新規アポトーシス誘導物質DDTCTの作用機構BMB20072007

    • Author(s)
      望月万里, 森田明典, 羽染芳宗, 井田紀子, 村田寛, 船津修, 菅原二三男, 池北雅彦
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Target Identificaiton of Small Drug Molecules2007

    • Author(s)
      Fumio Sugawara
    • Organizer
      5th International Drug Discovery Symposium
    • Place of Presentation
      Shanghai
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] High-throughput and High-accuracy Drug-Target Identifications2007

    • Author(s)
      Fumio Sugawara, Yoichi Takakusaghi, Kouji Kuramochi
    • Organizer
      The 4th Takeda Science Foundation Symposium on PharmaScience: On the Fronthiers of Chemical Biology
    • Year and Date
      2007-12-03
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Identification of cyclosporin A binding protein CSBP that plays a critical role in hepatitis C virus genome replication2007

    • Author(s)
      Hiroeki Sahara, Kengo Morohashi, Koichi Watashi, Yoko Mori, Kazuki Iwabata, Wataru Tsutae, Hiroki Miyashita, Kokichi Kikuchi, Kunitada Shimotohno, Kengo Sakaguchi, Noriyuki Sato, Fumio Sugawara
    • Organizer
      第66回日本癌学会学術総会
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法によるカンプトテシンの新規分子標的hEP1受容体細胞内第3ループの同定2007

    • Author(s)
      高草木洋一, 太田慶祐, 倉持幸司, 高草木香織, 小林進, 菅原二三男, 坂口謙吾
    • Organizer
      日本ケミカルバイオロジー研究会
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7 phage display法を用いたインターフェロン-α結合タンパク質の探索2007

    • Author(s)
      今井孝彦, 斉藤雄己, 石一智, 倉持幸司, 渡士幸一, 佐原弘益, 下遠野邦忠, 菅原二三男
    • Organizer
      日本農芸化学会2007年度大会
    • Year and Date
      2007-03-25
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法お用いたポドフィロトキシン結合タンパク質の探索2007

    • Author(s)
      斉藤雄己, 倉持幸司, 高田慶一, 菅原二三男
    • Organizer
      日本ケミカルバイオロジー研究会
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] Aspergione A及びBの提出構造式の訂正と2007

    • Author(s)
      倉持幸司, 齊藤史代, 中崎敦夫, 高橋徳行, 水品善之, 小林進, 菅原二三男
    • Organizer
      Pseudodeflectusinの生物活性日本農芸化学会2007年度大会
    • Year and Date
      2007-03-25
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法によるトラニラスト結合タンパク質の同定2007

    • Author(s)
      平山智子, 高草木洋一, 石一智, 倉持幸司, 竹内倫文, 菅原二三男
    • Organizer
      日本ケミカルバイオロジー研究会
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 抗腫瘍抗生物質fostriecinはプロテインフォスファターゼ2AのCys269-Lys283領域と共有結合する2007

    • Author(s)
      竹内倫文, 高橋徳行, 石一智, 倉持幸司, 菅原二三男
    • Organizer
      日本ケミカルバイオロジー研究会
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] ニンニク由来の含硫黄物質群のDNAポリメラーゼ分子種選択的阻害活性とヒト癌細胞増殖抑制活性BMB20072007

    • Author(s)
      西田真之, 羽田尚彦, 吉田英生, 木元貴士, 倉持幸司, 菅原二三男, 米澤裕子, 栗山磯子, 坂口謙吾, 吉田弘美, 水品善之
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 低分子化合物の高性能な標的探索を可能とするファージディスプレイ法の確立BMB20072007

    • Author(s)
      高草木洋一, 高木真奈美, 草柳友恵, 倉持幸司, 宮野友香, 高草木香織, 菅原二三男, 小林進, 坂口謙吾
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] T7ファージディスプレイ法によるポドフィロトキシンの新規結合タンパク質の探索2007

    • Author(s)
      斉藤雄己, 高田慶一, 倉持幸司, 菅原二三男
    • Organizer
      日本農芸化学会2007年度大会
    • Year and Date
      2007-03-25
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] カバノアナタケから同定された新規アポトーシス誘導物質DDTCTの作用機構2007

    • Author(s)
      望月万里, 森田明典, 羽染芳宗, 井田紀子, 村田寛, 船津修, 菅原二三男, 池北雅彦
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] ファージディスプレイ法を用いたneoechinulin Aが活性作用を示す際のターゲットタンパク及び、neoechinulin A生合成に関る遺伝子の探索2007

    • Author(s)
      堀内桃子, 竹野正洋, 倉持幸司, 菅原二三男, 鎌倉高志
    • Organizer
      日本ケミカルバイオロジー研究会
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-19380066
  • [Presentation] 固相有機合成用樹脂を用いたアフィニティービーズの標的タンパク質探索への応用BMB20072007

    • Author(s)
      宮野友香, 倉持幸司, 武内亮, 榎本好宏, 草柳友恵, 高草木洋一, 中崎敦夫, 小林進, 菅原二三男, 坂口謙吾
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19380066
  • 1.  KAMISUKI Shinji (30553846)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 2.  ISHIMOTO Masao (20355134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Tsukuda Senko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  Iwamoto Masashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 5.  Ohashi Hirofumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  松永 幸大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  渡士 幸一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 8.  古賀 浩徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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