SHINOMIYA Takahisa 四宮貴久

… Alternative Names

四宮貴久シノミヤタカヒサ

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Researcher Number	30196414
External Links
Affiliation (based on the past Project Information) *help	2013: 東京理科大学, 理工学部応用生物科学科, 教授 2005: 国立成育医療センター(研究所), RI管理室, 室長 2004: 国立成育医療センター研究所, RI管理室, 室長 2000: National Children's Medical Research Center, Department of Experimental Surgery & Bioengineering, Division of Research Promotion, Chief Researcher, 小児医療研究センター・実験外科生体工学部, 室長 1999 – 2000: 国立小児病院, 小児医療研究センター・共同利用室, 室長 … More 1999: 国立小児病院, 小児医療研究センター・共同利用研究室, 室長 1998: 国立小児病院, 小児医療研究センター・共同研究室部長, 室長 1998: 国立小児病院, 小児医療研究センター・実験外科生体工学部, 室長 1997: 国立小児病院, 小児医療研究センター・共同利用室, 室長 1997: Director, Dept. Of Biosystem, National Children's Medical Research Center, 小児医療研究センター・共同研究室, 室長 1996: 国立小児病院小児医療研究センター, 実験外科生体工学部, 室長 1995: National Children's Medical Research Center, 小児医療研究センター・共同利用研究室, 室長 1995: 国立小児病院, 小児医療研究センター・実験外科生体工学部, 室長 Less
Review Section/Research Field	Principal Investigator General surgery / General surgery Except Principal Investigator General surgery / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator Fas-ligand / Fas / Apoptosis / Gene therapy / Xenograft / Crm A / 肝 / PK15 / アデノウイルス・ベクター / FasL … More / アポトーシス / 遺伝子治療 / 異種移植 / CrmA / Lpr mice / rat liver / organ transplantation / B-galactosidase / adenovirus vector / HVJ-liposome / ラット心 / CTLA4Ig / アデノウィルスベクター / ラット肝 / β-galactosidase / 寛症寛容 / 劇症肝炎 / lprマウス / 臓器移植 / Fas-Ligend / Cre-loxpシステム / HVJ-リポゾーム / アデノウイルスベクター / 核移植 / サイトプラスト / 細胞脱核法 / 細胞融合 / ES細胞 … More Except Principal Investigator FTY720 / FasL / アポトーシス / loxP / Cre / CTLA4Ig / CrmA / 心移植 / Fas / ラット / 肝移植 / 遺伝子導入 / heart transplantation / liver transplantation / adenovirus vector / 免疫貴容 / cre I lox P / HVJ-リポゾーム / アデノウィルスベクター / Fash / Cre-loxP system / caspase / 拒絶反応 / CD28 / B7.2 / 相乗的免疫抑制効果 / 共刺激分子 / アデノウイルスベクター / cyclosporin / Dogs / Rate / Organ Transplantation / Apoptosis / Lsaria sinclairii / ISP-1 / シクロスポリン / イヌ / Isaria sinclairii / lpr-マウス / 臓器移植 / 免疫寛容 / 紫外線 / 皮膚がん / ナノパーティクル / ネクローシス / 脂質過酸化 / 酸化ストレス / 活性酸素 / 細胞死 / 酸化チタン / 光触媒 Less

Study of cell death-inducing effect enhanced by combined use of anatase-type titanium dioxide and a physiologically active substance
- Principal Investigator
  
  YOSHIMI Yoji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tokyo University of Science
体細胞を脱核幹細胞と融合して幹細胞化する試みPrincipal Investigator
- Principal Investigator
  
  四宮貴久
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  National Research Institute for Child Health and Development
The basic research for the rejection regulation in xeno-organtransplantation by the gene thearpyPrincipal Investigator
- Principal Investigator
  
  SHINOMIYA Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Children's Medical.Research Center
The basic research of the gene thearpy for immune regulation in organ transplantaionPrincipal Investigator
- Principal Investigator
  
  SHINOMIYA Takashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Children's Medical Research Center
Induction of transplantation tolerance based on bio-molecular technique
- Principal Investigator
  
  SUZUKI Seiichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  General surgery
- Research Institution
  National Children's Medical Research Center
Induction of transplantation tolerance based on lymphocyte apoptosis
- Principal Investigator
  
  SUZUKI Seiichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  National Children's Medical Research Center

All 2013 2012

All Journal Article Presentation

[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement2013
- Author(s)
  M Takeyoshi, S Sakemoto, I Shiina, K Nakata, K Fujimori, Y Wang, E Umeda, C Watanabe, S Uetake, T Yamori, S Dan, Y Yoshimi, T Shinomiya, M Ikekita
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651054
[Journal Article] SUTAF, a novel β-methoxyacrylate derivative, promotes neurite outgrowth with extracellular signal-regulated kinase and c-jun N-terminal kinase activation.2012
- Author(s)
  Nagahara Y, Suzuki E, Sekine Y, Uchiro H, Yoshimi Y, Shinomiya T, Ikekita M
- Journal Title
  
  Europian Juornal of Pharmacology
  
  Volume: 694 Issue: 1-3 Pages: 53-59
- DOI
  10.1016/j.ejphar.2012.08.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651054
[Presentation] 環状グアニジン構造を有する新規化合物RK-96の制がん剤としての可能性2012
- Author(s)
  清水理加, 吉見陽児, 横山翔, 岩下治弘, 袴田真矢, 斎藤隆夫, 四宮貴久, 池北雅彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24651054
[Presentation] 新規タモキシフェン類縁体リダイフェン-Bによるオートファジー誘導2012
- Author(s)
  長原礼宗, 酒本聖也, 梅田絵梨, 渡邊千尋, 植竹祥子, 吉見陽児, 四宮貴久, 池北雅彦, 椎名勇
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24651054
[Presentation] 新規細胞死誘導剤リダイフェンGの作用機構の解析並びに標的分子の同定2012
- Author(s)
  羽鳥麻奈美, 山本卓, 友光裕子, 椎名勇, 梅田絵梨, 戸田年総, 大篭友博, 岩本真知子, 森田明典, 渡邊千尋, 植竹祥子, 矢守隆夫, 吉見陽児, 四宮貴久, 池北雅彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24651054
[Presentation] 腎細胞がんの診断マーカーの探索2012
- Author(s)
  田中信太郎, 金子直樹, 吉見陽児, 四宮貴久, 池北雅彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24651054
[Presentation] リダイフェン-Gは強力なオートファジー誘導剤である2012
- Author(s)
  山本卓, 吉見陽児, 四宮貴久, 羽鳥麻奈美, 長原礼宗, 梅田絵梨, 渡邊千尋, 植竹祥子, 椎名勇, 池北雅彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24651054

1. RII Kou (60321890)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. SUZUKI Seiichi (00111386)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. ENOSAWA Shin (40232962)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OKUYAMA Torayuki (40177192)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAMURA Akihiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YOSHIMI Yoji (70609362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. IKEKITA Masahiko (70138981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. KIMURA Hiromitsu (80115477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKAJIMA Hiroo (70275212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AMEMIYA Hiroshi (80009563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 福井雅之 (60392502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 刀祢重信 (70211399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAKEFUDA Toshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHINOMIYA Takahisa 四宮 貴久

四宮 貴久 シノミヤ タカヒサ

Research Projects

Research Products

Co-Researchers

Study of cell death-inducing effect enhanced by combined use of anatase-type titanium dioxide and a physiologically active substance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

体細胞を脱核幹細胞と融合して幹細胞化する試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The basic research for the rejection regulation in xeno-organtransplantation by the gene thearpyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The basic research of the gene thearpy for immune regulation in organ transplantaionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of transplantation tolerance based on bio-molecular technique

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of transplantation tolerance based on lymphocyte apoptosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement2013

Author(s)

Journal Title

Data Source

[Journal Article] SUTAF, a novel β-methoxyacrylate derivative, promotes neurite outgrowth with extracellular signal-regulated kinase and c-jun N-terminal kinase activation.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 環状グアニジン構造を有する新規化合物RK-96の制がん剤としての可能性2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規タモキシフェン類縁体リダイフェン-Bによるオートファジー誘導2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規細胞死誘導剤リダイフェンGの作用機構の解析並びに標的分子の同定2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 腎細胞がんの診断マーカーの探索2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] リダイフェン-Gは強力なオートファジー誘導剤である2012

Author(s)

Organizer

Place of Presentation

Data Source

SHINOMIYA Takahisa 四宮貴久

四宮貴久シノミヤタカヒサ