OGAWA Koji 小川幸志

Researcher Number	30204077
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2011: Wakayama Medical University, School of Medicine, Associate Professor 2005 – 2006: 和歌山県立医科大学, 医学部, 助教授 2001 – 2004: 和歌山県立医科大学, 医学部, 講師 1997 – 2000: 和歌山県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator セボフルラン / 血管内皮細胞 / 揮発性麻酔薬 / Protein kinases / Intracellular Ca^<2+> concentration / Isoflurane / Sevoflurane / Vascular smooth muscle / Angiotensin II / PKC … More / プロポフォール / 蛋白リン酸化酵素 / 細胞内Ca^<2+>濃度 / イソフルラン / 血管平滑筋 / アンギオテンシン / ANESTHETICS / ENDOTHELIUM-DEPENDENT RELAXATION / INTRACELLULAR CALCIUM CONCENTRATION / VASCULAR ENDOTHELIUM / 麻酔薬 / 内皮依存性弛緩反応 / 細胞内カルシウムイオン濃度 / 弛緩反応 / 糖尿病 / 一酸化窒素 / スタチン / カフェイン / 腸間膜動脈 / 脳動脈 / 筋小胞体 / 脳血管 … More Except Principal Investigator イソフルラン / 脳微小血管 / グリベンクラミド / ATP感受性カリウムチャネル / 麻酔薬 / 局所麻酔薬 / 揮発性麻酔薬 / 一酸化窒素 / 糖尿病 / Protein kinases / Intracellular Ca^<2+> concentration / Diabetes Mellitus / Volatile anesthetics / Vascular smooth muscle / Angiotensin II / カルシウム / 血管収縮性 / 糖尿病ラット / セボフルラン / 血管平滑筋 / Cerebral intraparenchymal arterioles / Isoflurane / Neuronal nitric oxide synthase / Hypertension / Inward rectifier K^+ channels / Lidocaine / ATP-sensitive K^+ channels / 高炭酸ガス / ノックアウトマウス / 神経型一酸化窒素合成酵素 / 脳実質内微小血管 / 神経型一酸化窒素合成酵素遺伝子 / 高血圧 / 内向き整流性カリウムチャネル / リドカイン / LOCAL ANESTHETICS / VOLATILE ANESTHETICS / K_+ / Ca2_+ / CEREBRAL ARTERIAL SMOOTH MUSCLE / 腸間膜動脈平滑筋 / ハロタン / レブクロマカリム / イオンチャネル / Ca^<2+>(カルシウムイオン) / 脳動脈 / カリウムチャンネル / Ca^<<2+>>(カルシウムイオン) / 脳動脈平滑筋 / 血管内皮細胞 / AKTタンパク質 / Aktタンパク質 / Phosphoinositole 3-kinase / 内皮型一酸化窒素合成酵素 / スタチン Less

The mechanisms of the effect of statin on acute improvement of endothelial dysfunction
- Principal Investigator
  
  SETO Yoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
The anesthetic modulation of the protective effect of statin on the endothelium function in diabetic and hypertensive animal models.Principal Investigator
- Principal Investigator
  
  OGAWA Koji
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
Intracellular regulation and anesthetic modification regarding the augmentation of vascular contraction in diabetic condition
- Principal Investigator
  
  KAKUTANI Tetsuya
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
Role of Protein Kinases Phosphorylation in the Inhibitory Effect of Volatile Anesthetics on Vascular Smooth Muscle Contraction.Principal Investigator
- Principal Investigator
  
  OGAWA Koji
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
The research regarding the function of cerebral microvasculature using gene-knockout animals and the role of anesthetic drugs
- Principal Investigator
  
  HATANO Yoshio
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University
EFFECTS OF GENERAL ANESTHETICS ON INTRACELLULAR CALCIUM CONCENTRATION AND NITRIC OXIDE PRODUCTION OF VASCULAR ENDOTHELIUMPrincipal Investigator
- Principal Investigator
  
  OGAWA Koji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  WAKAYAMA MEDICAL UNIVERSITY
A STUDY FOR INTRACELLULAR CALCIUM REGULATING MECHANISMS IN ARTERIAL SMOOTH MUSCLE AND THE EFFECT OF ANESTHETICS ON THESE MECHANISMS
- Principal Investigator
  
  HATANO Yoshio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  WAKAYAMA MEDICAL COLLEGE
脳動脈平滑筋細胞内Ca調節機構における筋小胞体の特異性と麻酔薬作用に関する研究Principal Investigator
- Principal Investigator
  
  小川幸志
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Wakayama Medical University

All 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Reduction of adhesion formation by an angiotensin type 1 receptor antagonist.2011
- Author(s)
  Tokinaga Y, Kimoto Y, Ogawa K, Mizumoto K, Tange K, Hatano Y
- Journal Title
  
  Langenbecks Arch Surg
  
  Volume: 396 Pages: 127-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Differential vasodilation response to olprinone in rabbit renal and common carotid arteries2010
- Author(s)
  Minonishi T, Ogawa K, Tokinaga Y, Negoro T, Kimoto Y, Hatano Y
- Journal Title
  
  J Anesth
  
  Volume: 24 Pages: 61-66
- NAID
  10027265635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591986
[Journal Article] The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction2010
- Author(s)
  Shimogai M, Ogawa K, Tokinaga Y, Yamazaki A, Hatano Y
- Journal Title
  
  J Anesth
  
  Volume: 24 Pages: 893-900
- NAID
  10027741425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591986
[Journal Article] The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.2010
- Author(s)
  Shimogai M, Ogawa K, Tokinaga Y, Yamazaki A, Hatano Y
- Journal Title
  
  J Anesth
  
  Volume: 24 Pages: 893-900
- NAID
  10027741425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591986
[Journal Article] Sevoflurane does not alter norepinephrine-induced intracellular Ca^<2+> changes in the diabetic rat aorta2010
- Author(s)
  Fujii K, Ogawa K, Tokinaga Y, Iranami H, Hatano Y
- Journal Title
  
  Can J Anesth
  
  Volume: 57 Pages: 1995-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591986
[Journal Article] Sevoflurane does not alter norepinephrine-induced intracellular Ca^<2+> changes in the diabetic rat aorta2010
- Author(s)
  Fujii K, Ogawa K, Tokinaga Y, Iranami H, Hatano Y
- Journal Title
  
  Can J Anesth
  
  Volume: 57 Pages: 1095-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.2010
- Author(s)
  Shimogai M, Ogawa K, Tokinaga Y, Yamazaki A, Hatano Y
- Journal Title
  
  J Anesth 24
  
  Pages: 893-900
- NAID
  10027741425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.2010
- Author(s)
  Shimogai M, Ogawa K, Tokinaga Y, Yamazaki A, Hatano Y
- Journal Title
  
  J Anesth
  
  Volume: 24 Pages: 893-900
- NAID
  10027741425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Sevoflurane does not alter norepinephrine-induced intracellular Ca2+ changes in the diabetic rat aorta.2010
- Author(s)
  Fujii K, Ogawa K, Tokinaga Y, Iranami H, Hatano Y
- Journal Title
  
  Can J Anesth 57
  
  Pages: 1095-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Differential vasodilation response to olprinone in rabbit renal and common carotid arteries.2010
- Author(s)
  Minonishi T, Ogawa K, Tokinaga Y, Negoro T, Kimoto Y, Hatano Y
- Journal Title
  
  J Anesth 24
  
  Pages: 61-66
- NAID
  10027265635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Differential vasodilation response to olprinone in rabbit renal and common carotid arteries2010
- Author(s)
  Minonishi T, Ogawa K, Tokinaga Y, et al.
- Journal Title
  
  Journal of Anesthesia 24
  
  Pages: 61-66
- NAID
  10027265635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Differential vasodilation response to olprinone in rabbit renal and common carotid arteries2010
- Author(s)
  Minonishi T, Ogawa K, Tokinaga Y, Negoro T, Kimoto Y, Hatano Y
- Journal Title
  
  J Anesth 24
  
  Pages: 61-66
- NAID
  10027265635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Sevoflurane does not alter norepinephrine-induced intracellular Ca2+changes in the diabetic rat aorta2010
- Author(s)
  Fujii K, Ogawa K, Tokinaga Y, Iranami H, Hatano Y
- Journal Title
  
  Can J Anesth
  
  Volume: 57 Pages: 1095-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591986
[Journal Article] Volatile Anesthetics Inhibit Angiotensin II-induced Vascular Contraction by Modulating Myosin Light Chain Phosphatase Inhibiting Protein, CPI-17 and Regulatory Subunit, MYPT1 Phosphorylation.2009
- Author(s)
  Qi F, Ogawa K, Tokinaga Y, Uematsu N, Minonishi T, Hatano Y
- Journal Title
  
  Anesth Analg 109
  
  Pages: 412-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Volatile Anesthetics Inhibit Angiotensin II-induced Vascular Contraction by Modulating Myosin Light Chain Phosphatase Inhibiting Protein, CPI-17 and Regulatory Subunit, MYPTl Phosphorylation2009
- Author(s)
  Qi Feng, Ogawa K, et al.
- Journal Title
  
  Anesthesia & Analgesia (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Volatile Anesthetics Inhibit Angiotensin II-induced Vascular Contraction by Modulating Myosin Light Chain Phosphatase Inhibiting Protein, CPI-17 and Regulatory Subunit, MYPT1 Phosphorylation2009
- Author(s)
  Qi Feng, Ogawa K, Tokinaga Y, et al.
- Journal Title
  
  Anesthesia & Analgesia 109
  
  Pages: 412-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Volatile Anesthetics Inhibit Angiotensin II-induced Vascular Contraction by Modulating Myosin Light Chain Phosphatase Inhibiting Protein, CPI-17 and Regulatory Subunit, MYPT1 Phosphorylation2009
- Author(s)
  Qi Feng, Ogawa K, Tokinaga Y, Uematsu N, Minonishi T, Hatano Y
- Journal Title
  
  Anesth Analg 109
  
  Pages: 412-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Mechanism of the ropivacaine-induced increase in intracellular Ca2+ concentration in rat aortic smooth muscle.2007
- Author(s)
  Tokinaga Y, Ogawa K, Yu J, Kuriyama T, Minonishi T, Hatano Y
- Journal Title
  
  Acta Anaesthsiol Scand 51
  
  Pages: 1155-1160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] The mechanism behind the inhibitory effect of iso flurane on Angiotensin II-induced contraction is different from that of sevoflurane2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano, Y
- Journal Title
  
  Anesth Analg 105
  
  Pages: 97-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] The mechanism behind the inhibitory effect of isoflurane on angiotensin II-induced contraction is different from that of sevoflurane2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg 105
  
  Pages: 97-102
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] The mechanism behind the inhibitory effect of isoflurane on Angioten sin II-induced contraction is different from that of sevoflurane.2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg 105
  
  Pages: 97-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] The mechanism behind the inhibitory effect of isoflurane on Angiotensin II-induced contraction is different from that of sevoflurane.2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg 105
  
  Pages: 97-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] Mechanism of the ropivacaine-induced increase in intracellular Ca^<2+> concentration in rat aortic smooth muscle2007
- Author(s)
  Tokinaga Y, Ogawa K, Yu J, Kuriyama T, Minonishi T, Hatano Y
- Journal Title
  
  Acta Anaesthesiol Scand 51
  
  Pages: 1155-1160
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Mechanism of the ropivacaine-induced increase in intracellUlar Ca2+concentration in rat aortic smooth muscle.2007
- Author(s)
  Tokinaga Y, Ogawa K, Yu J, Kuriyama T, Minonishi T, Hatano Y
- Journal Title
  
  Acta Anaesthesiol Scand 51
  
  Pages: 1155-1160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Effects of isoflurane and sevoflurane anesthesia on arteriovenous shunt flow in the lower limb of diabetic patients without neuropathy.2007
- Author(s)
  Negoro T, Mizumoto K, Ogawa K, Hironaka Y, Kakutani T, Hatano Y
- Journal Title
  
  Anesthesiology 107
  
  Pages: 45-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591815
[Journal Article] The mechanism behind the inhibitory effect of isoflurane on angiotensin II-induced contraction is different from that of sevoflurane.2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg 105
  
  Pages: 97-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Effects of isoflurane and sevoflurane anesthesia on arteriovenous shunt flow in the lower limb of diabetic patients without neuropathy2007
- Author(s)
  Negoro T, Mizumoto K, Ogawa K, Hironaka Y, Kakutani T, Hatano Y
- Journal Title
  
  Anesthesiology 107
  
  Pages: 45-52
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Effects of isoflurane and sevoflurane anesthesia on arteriovenous shunt flow in the lower limb of diabetic patients without neuropathy.2007
- Author(s)
  Negoro T, Mizumoto K, Ogawa K, Hironaka Y, Kakutani T, Hatano Y
- Journal Title
  
  Anesthesiology 107
  
  Pages: 45-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] The mechanism behind the inhibitory effect of isoflurane on Angiotensi II-induced contraction is different from that of sevoflurane.2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg (in press
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Effects of isoflurane and sevoflurane anesthesia onarteriovenous shunt flow in the lower limb of diabetic patients without neuropathy2007
- Author(s)
  Negoro T, Mizumoto K, Ogawa K, Hironaka Y, Kakutani T, Hatano, Y
- Journal Title
  
  Anesthesiology 107
  
  Pages: 45-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] the mechanism behind inhibitory effect of isoflurane on Angiotensin II-induced contraction is different from that of sevoflurane.2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano Y
- Journal Title
  
  anesth Analg (In press)
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] The mechanism behind the inhibitory effect of isoflurane on Angiotensin II-induced contraction is different from that of sevoflurane.2007
- Author(s)
  Ishikawa A, Ogawa K, Tokinaga Y, Uematsu N, Mizumoto K, Hatano Y
- Journal Title
  
  Anesth Analg (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats.2006
- Author(s)
  Nakahata K, Kinoshita H, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  anesth Analg 102
  
  Pages: 571-6
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats.2006
- Author(s)
  Nakahata K, Kinoshita, H, Tokinaga Y, Ishida Y, Kimoto Y, Dojo M, Mizumoto K, Ogawa K, Hatano Y
- Journal Title
  
  Anesth Analg 102
  
  Pages: 571-6
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Comparison of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction.2005
- Author(s)
  Yu J, Mizumoto K, Kakutani T, Hasegawa A, Ogawa K, Hatano Y
- Journal Title
  
  Acta Anaestesiol Scand 49
  
  Pages: 852-858
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Comparioson of the effects of isoflurane and sevoflurane on proteir tyrosine phosphorylation-mediated vascular contraction.2005
- Author(s)
  Yu J, Mizumoto K, Kakutani T, Hasegawa A, Ogawa K, Hatano Y
- Journal Title
  
  Acta Anaesthesiol Scand 49
  
  Pages: 852-858
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Comparison of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction.2005
- Author(s)
  Yu J, Mizumoto K, Kakutani T, Hasegawa A, Ogawa K, Hatano Y
- Journal Title
  
  Acta Anaesthesiol Scand 49
  
  Pages: 852-858
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Halothane does not protect against vascular injury in isolate cerebral and mesenteric arteries.2005
- Author(s)
  Ogawa K, Tokinaga Y, Iwahashi S, Mizumoto K, Hatano Y
- Journal Title
  
  Can J Anesth 52
  
  Pages: 870-877
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Comparison of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction2005
- Author(s)
  Yu J, Mizumoto K, Kakutani T, Hasegawa A, Ogawa K, Hatano, Y
- Journal Title
  
  Acta Anaesthesiol Scand 49(6)
  
  Pages: 852-858
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Sevoflurane enhances nitroglycerin tolerance in rat aorta : Implications for the desensitization of soluble guanylate cyclase possibly through the additive generation of superoxid anions and/or hydroxyl radicals within vascular smooth muscle2005
- Author(s)
  Kakutani T, Ogawa K, Hatano Y, Mizumoto K, Iwahashi S
- Journal Title
  
  Anesth Analg 101
  
  Pages: 1015-1022
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] The inhibitory effects of sevoflurane on angiotensin II-induced, P44/4 mitogen-activated protein kinase-mediated contraction of rat aortic smooth muscle.2005
- Author(s)
  Yu J, Mizumoto K, Tokinaga Y, Ogawa K Hatano Y
- Journal Title
  
  Anesth Analg 101
  
  Pages: 315-321
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Sevoflurane enhances nitroglycerin tolerance in rat aorta : Implications for the desensitization of soluble guanylate cyclase possibly through the additive generation of superoxide anions and/or hydroxyl radicals within vascular smooth muscle.2005
- Author(s)
  Kakutani T, Ogawa K, Hatano Y, Mizumoto K, Iwahashi S
- Journal Title
  
  Anesth Analg 101
  
  Pages: 1015-1022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Sevoflurane enhances nitroglycerin tolerance in rat aorta : Implication for the desensitization of soluble guanylate cyclase possibly throug the additive generation of superoxide anions and/or hydroxyl radical within vascular smooth muscle.2005
- Author(s)
  Kakutani T, Ogawa K, Hatano Y, Mizumoto K, Iwahashi S
- Journal Title
  
  Anesth Analg 101
  
  Pages: 1015-1022
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Halothane does not protect against vascular injury in isolated cerebra and mesenteric arteries.2005
- Author(s)
  Ogawa K, Tokinaga Y, Iwahashi S, Mizumoto K, Hatano Y
- Journal Title
  
  Can J Anesth 52
  
  Pages: 870-877
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Sevoflurane enhances nitroglycerin tolerance in rat aorta.2005
- Author(s)
  Kakutani T, Ogawa K, Hatano Y, Mizumoto K, Iwahashi S
- Journal Title
  
  Anesth Analg 101
  
  Pages: 1015-1022
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] Sevoflurane enhances nitroglycerin tolerance in rat aorta : Implications for the desensitization of soluble guanylate cyclase possibly through the additive generation of superoxide anions and/or hydroxyl radicals within vascular smooth muscle2005
- Author(s)
  Kakutani T, Ogawa K, Mizumoto K, Iwahashi S, Hatano, Y
- Journal Title
  
  Anesth Analg 101(4)
  
  Pages: 1015-1022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] he inhibit ory effects of sevoflurane on angiotensin II-induced, p44/42 mitogen-activated protein kinase-mediated contraction of rat aortic smooth muscle.2005
- Author(s)
  Yu J, Mizumoto K, Tokinaga Y, Ogawa K, Hatano, Y
- Journal Title
  
  Anesth Analg 101(2)
  
  Pages: 315-321
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650
[Journal Article] The inhibitory effects of sevoflurane on angiotensin II-induced, p44/42 mitogen- activated protein kinase-mediated contraction of rat aortic smooth muscle.2005
- Author(s)
  Yu J, Mizumoto K, Tokinaga Y, Ogawa K, Hatano Y
- Journal Title
  
  Anesth Analg 101
  
  Pages: 315-321
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] The inhibitory effects of sevoflurane on angiotensin II-induced, p44/42 mitogen-activated protein kinase-mediated contraction of rat aortic smooth muscle.2005
- Author(s)
  Yu J, Mizumoto K, Kakutani T, Hasegawa A, Ogawa K, Hatano Y
- Journal Title
  
  Anesth Analg 101
  
  Pages: 315-321
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Halothane does not protect against vascular injury in isolated cerebral and mesenteric arteries.2005
- Author(s)
  Ogawa K, Tokinaga Y, Iwahashi S, Mizumoto K, Hatano Y
- Journal Title
  
  Can J Anesth 52
  
  Pages: 870-877
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Comparioson of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction.2005
- Author(s)
  Yu J, Mizumoto K, Kakutani T, Hasegawa A, Ogawa K, Hatano Y
- Journal Title
  
  Acta Anaesthesiol Scand 49
  
  Pages: 850-858
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Sevoflurane Inhibits Angiotensin II-induced, Protein Kinase C-mediated but Not Ca^<2+>-elicited Contraction of Rat Aortic Smooth Muscle.2004
- Author(s)
  Yu J, Tokinaga Y, Ogawa K, Iwahashi S, Hatano Y
- Journal Title
  
  Anesthesiology 100
  
  Pages: 879-884
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Sevoflurane Inhibits Angiotensin II-induced, Protein Kinase C-mediated but Not Ce2^<+>-elicited Contraction of Rat Aortic Smooth Muscle.2004
- Author(s)
  Yu J, Tokinaga Y, Ogawa K, Iwahashi S, Hatano Y
- Journal Title
  
  Anesthesiology 100
  
  Pages: 879-884
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] The inhibitory effects of isoflurane on protein tyrosine phosphorylation-modulated contraction of rat aortic smooth muscle2004
- Author(s)
  Yu J, Ogawa K, Tokinaga Y, Mizumoto K, Kakutani T, Hatano Y
- Journal Title
  
  Anesthesiology 101:6
  
  Pages: 1325-1331
- Data Source
  KAKENHI-PROJECT-13470327
[Journal Article] The Inhibitory effects of isoflurane on protein tyrosine phosphorylation-modulated contraction of rat aortic smooth muscle.2004
- Author(s)
  Yu J, Ogawa K, Tokinaga Y, Mizumoto K, Kakutani T, Hatano Y
- Journal Title
  
  Anesthesiology 101
  
  Pages: 1325-1331
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] The vascular relaxing effects of sevoflurane and isoflurane are more important in hypertensive than in normotensive rats2004
- Author(s)
  Yu J, Ogawa K, Tokinaga Y, Iwahashi S, Hatano Y
- Journal Title
  
  CAN J ANESTH 51:10
  
  Pages: 979-985
- Data Source
  KAKENHI-PROJECT-13470327
[Journal Article] The vascular relaxing effects of sevoflurane and isoflurane are more important in hypertensive than in normotensive rats.2004
- Author(s)
  Yu J, Ogawa K, Tokinaga Y, Iwahashi S, Hatano Y
- Journal Title
  
  Can J Anesth 51
  
  Pages: 979-985
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591557
[Journal Article] Effects of halothane and isoflurane on acetylcoline-induced, endothelium-dependent vasodilation in perfused rat mesenteric arterial beds.2003
- Author(s)
  Tsukiyama Y, Iranami H, Kinoshita H, Ogawa K, Hatano Y
- Journal Title
  
  J Anesth 17
  
  Pages: 13-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470327
[Journal Article] Effects of halothane and isoflurane on acetylcholine-induced, endothelium-dependent vasodilation in perfused rat mesenteric arterial beds.2003
- Author(s)
  Tsukiyama Y, Iranami H, Kinoshita H, Ogawa K, Hatano Y
- Journal Title
  
  J Anesth 17
  
  Pages: 13-21
- NAID
  50000769957
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470327
[Presentation] The Effect of Sevoflurane on Simvastatin-Induced eNOS Expression in Cultured Endothelial Cells.2010
- Author(s)
  Tange K, Kawashima K, Tokinaga Y, Ogawa K, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-21591986
[Presentation] The Effect of Sevoflurane on Simvastatin-Induced eNOS Expression in Cultured Endothelial Cells.2010
- Author(s)
  Tange K, Kawashima K, Tokinaga Y, Ogawa K, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesth esiologists
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] The Effect of Sevoflurane on Simvastatin-Induced eNOS Expression in Cultured Endothelial Cells.2010
- Author(s)
  Tange K, Kawashima K, Tokinaga Y, Ogawa K, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologists.
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] The Effect of Sevoflurane on Simvastatin-Induced eNOS Expression in Cultured Endothelial Cells.2010
- Author(s)
  Tange K, Kawashima K, Tokinaga Y, Ogawa K, Hatano Y
- Organizer
  2010 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-21591986
[Presentation] 急性シンバスタチン投与による一酸化窒素合成酵素発現に及ぼすセボフルランの影響2010
- Author(s)
  丹下和晃、時永泰行、谷奥匡、平井亜葵、小川幸志、畑埜義雄
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡市
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Sevoflurane inhibits the increase in statin-Induced endothelial nitric oxide synthase expression2009
- Author(s)
  Tange K, Tokinaga Y, Ogawa K, Hatano Y
- Organizer
  2009 Annual Meeting of Anerican Society of Anesthesiologists
- Place of Presentation
  米国ルイジアナ州ニューオリンズ
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Simvastatin restores the impaired endothelium-dependent relaxation in diabetic rats.2009
- Author(s)
  Sugimoto K, Ogawa K, Tokinaga Y, Tange K, Hatano Y
- Organizer
  2009 Annual Meeting of American Society of Anesthesiologists.
- Place of Presentation
  New Orleans, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Simvastatin restores the impaired endothelium-dependent relaxation in diabetic rats2009
- Author(s)
  Sugimoto K, Ogawa K, Tokinaga Y, Tange K, Hatano Y
- Organizer
  2009 Annual Meeting of Anerican Society of Anesthesiologists
- Place of Presentation
  米国ルイジアナ州ニューオリンズ
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Sevoflurane inhibits the increase in statin-Induced endothelial nitric oxide synthase expression.2009
- Author(s)
  丹下和晃, 時永泰行, 小川幸志, 畑埜義雄
- Organizer
  2009 Annual Meeting of American Society of Anesthesiologists.
- Place of Presentation
  New Orleans, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] ウシ大動脈内皮細胞における一酸化窒素 (NO) 産生量に対するシンバスタチンの急性効果2009
- Author(s)
  丹下和晃, 時永泰行, 井上真理子, 佐古有希子, 小川幸志, 畑埜義雄
- Organizer
  日本麻酔科学会第56回学術集会
- Place of Presentation
  神戸市
- Year and Date
  2009-08-17
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] シンバスタチンは糖尿病における内皮依存性弛緩反応低下を回復させる2009
- Author(s)
  時永泰行、小川幸志、木本吉紀、槙野仁奈、阪中容、畑埜義雄
- Organizer
  日本麻酔科学会第56回学術集会
- Place of Presentation
  神戸市
- Year and Date
  2009-08-16
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] ウシ大動脈内皮細胞における一酸化窒素(NO)産生量に対するシンバスタチンの急性効果2009
- Author(s)
  丹下和晃、時永泰行、井上真理子、佐古有希子、小川幸志、畑埜義雄
- Organizer
  日本麻酔科学会第56回学術集会
- Place of Presentation
  神戸市
- Year and Date
  2009-08-16
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Volatile anesthetics inhibit AVP-induced vasoconstriction by modulating intracellular Ca2+ and Rho K.2008
- Author(s)
  Shimogai M, Tokinaga Y, Ogawa K, Iranami H, Hatano Y
- Organizer
  2008 Annual Meeting of American Society of Anesthesiologists.
- Place of Presentation
  Orlando, USA
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Acute effect of simvastatin on nitric oxide synthesis in bovine aortic endothelial cells.2008
- Author(s)
  Tange K, Tokinaga Y, Ogawa K, Kuriyama T, Hatano Y
- Organizer
  2008 Annual Meeting of American Society of Anesthesiologists.
- Place of Presentation
  Orlando, USA
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Acute Effect of Simvastatin on Nitric Oxide Synthesis in Bovine Aortic Endothelial Cells2008
- Author(s)
  Tange K, Tokinaga Y, Ogawa K, et al.
- Organizer
  2008 annual meeting of American Society of Anesthesiologist
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2008-10-21
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] セボフルランは摘出ラット大動脈のシンバスタチンによる血管弛緩反応を増強する2008
- Author(s)
  藤井啓介、小川幸志、時永泰行、岩橋静江、伊良波浩、畑埜義雄
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  横浜市
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Vasopressin restores the hyporesponsiveness of vascular smooth muscle to norepinephrinee in sepsis.2007
- Author(s)
  Yamazaki A, Tokinaga Y, Iranami H, Ogawa K, Hatano Y
- Organizer
  Annual meeting of American society of the anesthesiologists
- Place of Presentation
  San Francisco,CA,USA
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] Sevoflurane does not alter norepinephrine-induced intracellular Ca2+ change in diabetic rat aorta.2007
- Author(s)
  Fujii K, Ogawa K, Iranami H, Tokinaga Y, Hatano Y
- Organizer
  Annual meeting of American society of the anesthesiologists
- Place of Presentation
  San Francisco,CA,USA
- Data Source
  KAKENHI-PROJECT-19591815
[Presentation] The Effects of Sevoflurane and Isoflurane on Angiotensin II-Induced Vaso constriction in Hypertension2006
- Author(s)
  Nobuhiko, Uematsu, M. D. Tetsuya, Kakutani, M. D. Takaaki, Negoro M.D. Koji Ogawa, M.D. Yoshio Hatano, M.D.
- Organizer
  2006 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  Chicago, IL, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650
[Presentation] Sevoflurane Inhibits Angiotensin II-Induced, MAPK-Mediated Contraction of Rat Aortic Smooth Muscle2005
- Author(s)
  Koji, Ogawa, Jingui, Yu, Yasuyuki, Tokinaga, Tetsuya, Kakutani, Yoshio, Hatano
- Organizer
  2005 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  Atlanta, GA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650
[Presentation] Effects of Sevoflurane on the Activation of cAMP-and cGMP-Dependent Protein Kinases Induced by cAMP in Rat Aorta2005
- Author(s)
  Nobuhiko, Uematsu, Koji, Ogawa, Tetsuya, Kakutani, Keiko, Hama, Yoshio, Hatano
- Organizer
  2005 Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  Atlanta, GA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591650

1. HATANO Yoshio (70115913)

# of Collaborated Projects: 6 results

# of Collaborated Products: 69 results
2. MIZUMOTO Kazuhiro (50239258)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
3. SETO Yoko (30433353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MAEDA Hiroshi (80199629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAKUTANI Tetsuya (00264896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results

OGAWA Koji 小川 幸志

Research Projects

Research Products

Co-Researchers

The mechanisms of the effect of statin on acute improvement of endothelial dysfunction

Principal Investigator

Project Period (FY)

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Research Institution

The anesthetic modulation of the protective effect of statin on the endothelium function in diabetic and hypertensive animal models.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Intracellular regulation and anesthetic modification regarding the augmentation of vascular contraction in diabetic condition

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Protein Kinases Phosphorylation in the Inhibitory Effect of Volatile Anesthetics on Vascular Smooth Muscle Contraction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The research regarding the function of cerebral microvasculature using gene-knockout animals and the role of anesthetic drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EFFECTS OF GENERAL ANESTHETICS ON INTRACELLULAR CALCIUM CONCENTRATION AND NITRIC OXIDE PRODUCTION OF VASCULAR ENDOTHELIUMPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A STUDY FOR INTRACELLULAR CALCIUM REGULATING MECHANISMS IN ARTERIAL SMOOTH MUSCLE AND THE EFFECT OF ANESTHETICS ON THESE MECHANISMS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳動脈平滑筋細胞内Ca調節機構における筋小胞体の特異性と麻酔薬作用に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Reduction of adhesion formation by an angiotensin type 1 receptor antagonist.2011

Author(s)

Journal Title

Data Source

[Journal Article] Differential vasodilation response to olprinone in rabbit renal and common carotid arteries2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Sevoflurane does not alter norepinephrine-induced intracellular Ca^<2+> changes in the diabetic rat aorta2010

Author(s)

Journal Title

Data Source

[Journal Article] Sevoflurane does not alter norepinephrine-induced intracellular Ca^<2+> changes in the diabetic rat aorta2010

Author(s)

Journal Title

Data Source

[Journal Article] The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.2010

OGAWA Koji 小川幸志