tanaka toshiyuki 田中稔之

… Alternative Names

TANAKA Toshiyuki 田中稔之

田中稔之タナカトシユキ

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Researcher Number	30217054
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 兵庫医科大学, 薬学部, 教授 2018 – 2021: 兵庫医療大学, 薬学部, 教授 2007 – 2015: Hyogo University of Health Sciences, 薬学部, 教授 1999 – 2006: 大阪大学, 医学系研究科, 助教授 1998: 大阪大学, 医学部, 講師 … More 1994 – 1997: 大阪大学, 医学部, 助手 1994: 財団法人東京都臨床医学総合研究所, 免疫研究部門, 研究員 1993: 研究員 1992 – 1993: (財)東京都臨床医学総合研究所, 免疫研究部門, 研究員 1990: 東京都臨床医学総合研究所, 免疫研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Immunology / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Biological Sciences / Experimental pathology / Laboratory animal science / General pharmacology / Immunology
Keywords	Principal Investigator リンパ球ホーミング / リンパ節 / nepmucin / 細胞接着分子 / ケモカイン / 細胞接着 / 細胞外基質 / 高内皮細静脈(HEV) / 血管内皮細胞 / cDNAクローニング … More / 免疫チェックポイント / 癌免疫治療 / cell adhesion / 細胞動員 / 免疫学 / ローリング / 高内皮細静脈 / 獲得免疫 / ケモカイン結合分子 / leupaxin / 遺伝子発現 / 3'末端特異的cDNAライブラリ / EST / シグナル伝達 / 併用薬 / IL-18 / L-selectin / lymphocyte homing / Nepmucin / Endomucin / L-セレクチン / signal transduction / cell migration / focal contact / tyrosine phosphorylation / paxillin / 血管内細胞 / 自然免疫 / 細胞遊走 / L-セレクチンリガンド / 遺伝子発現プロフィル / 接着分子 / HEV / 組織形成 / 組織特異的遺伝子 / チロシンリン酸化 / NK細胞 / トランスジェニックマウス / 実臨床 / 抗腫瘍免疫応答 / 免疫関連有害事象 / 腫瘍ネオ抗原 / I型免疫応答 / バイオマーカー / rolling / chemokine / high endothelial venules / lymph nodes / L-レセレクチン / glycosylation / lymphocyte rolling / L-selectin ligands / high endothelial venules(HEVs) / HEV-2 / endomucin / 糖鎖修飾 / リンパ球ローリング / rote in / integrin / サイトカイン / 微小環境 / 制御性細胞 / MAdCAM-1 / 分化誘導 / ES細胞 / リンパ球 / 免疫細胞動員 / 腫瘍血管 / lysophospholipase D / autotaxin / コンドロイチン硫酸 / グリコサミノグリカン / プロテオグリカン / シアロムチン / angiomodulin / mac25 / BLC / CXCL13 / パイエル板 / インテグリン / 浸潤・転移 / 細胞運動 / パキシリン / TGF-β / ロイシンリッチリピート / 器官形成 / リンパ球再循環 / 高内皮細胞 / transmigration / 信号伝達 / CD44 / がん転移 / CD4^+T細胞 / 標的遺伝子 / 組織特異性 / IL-2レセプターβ鎖 / Thy-1+樹状表皮細胞 / IL-2レセプターB鎖 / IL-2 / サイトカインレセプタ-ファミリ- / 細胞内情報伝達 / cDNA / モノクロ-ナル抗体 / ILー2レセプタ- … More Except Principal Investigator CD44 / IL-18 / ケモカイン / プロテオグリカン / 転移 / L-セレクチン / 接着分子 / 免疫チェックポイント阻害薬 / 免疫関連有害事象 / 細胞外基質 / 炎症 / P-セレクチン / バーシカン / 内皮細胞 / 癌転移 / 自然リンパ球 / 免疫関連有害事象 (irAE) / 免疫チェックポイント / 肝傷害 / metastasis / extracellular matrix / PSG L-1 / P-selectin / hyaluronidase / hyaluronic acid / 血行性転移 / 癌細胞ローリング / リポソーム / セレクチン / 血管内皮細胞 / 細胞接着 / グリコサミノグリカン / PSGL-1 / ヒアルロニダーゼ / ヒアルロン酸 / sulfotransferase / endothelial cell / lymph node / chemokine / high endothelial venule / lymphocyte homing / リンパ球 / cDNAライブラリー / 組織特異的遺伝子 / 硫酸基転移酵素 / リンパ節 / HEV(高内皮細胞) / リンパ球ホーミング / SCID-Hu / SCID mouse / NK cell / IL-2 receptor beta chain / マウス / IL-2受容体 / 移植 / 腫瘍 / IL-1受容体beta鎖 / SCID-Huマウス / SCIDマウス / NK細胞 / IL-1受容体β鎖 / 免疫 / AT2受容体 / アンギオテンシンII / キマーゼ / アルドステロン / 急性腎障害 / シスプラチン / サイトカイン / 炎症・免疫 / 生体分子 / 免疫学 / バイオテクノロジー / 糖鎖 / 癌 / コンドロイチン硫酸 / 白血球浸潤 / シグナル伝達 / Fas / アポトーシス / ILー2受容体 / ILー2 Less

実臨床に基づく併用薬の抗腫瘍免疫応答の修飾機序の解明と癌免疫治療の最適化への応用Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hyogo Medical University
自然リンパ球の活性化が誘導する正常組織保護作用と抗腫瘍免疫の強化
- Principal Investigator
  
  大野喜也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hyogo Medical University
IL-18-induced type I immune response and regulation of immune checkpoints by tumor neoantigensPrincipal Investigator
- Principal Investigator
  
  Tanaka Toshiyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hyogo Medical University
  Hyogo University of Health Sciences
Overcoming immune-related adverse events (irAE) induced by immune checkpoint inhibitors
- Principal Investigator
  
  Ohno Yoshiya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hyogo University of Health Sciences
Regulation of immune-checkpoint by IL-18 and its application to cancer immunotherapyPrincipal Investigator
- Principal Investigator
  
  TANAKA Toshiyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hyogo University of Health Sciences
Tissue-specific trafficking of immune-competent cells mediated by lymph node-associated cell trafficking signals and regulation of immune-responses towards self components.Principal Investigator
- Principal Investigator
  
  TANAKA Toshiyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hyogo University of Health Sciences
Elucidation of the mechanism in cisplatin-induced renal failure anddevelopment of drug therapy aimed at the mitigation of the renal toxicity of cisplatin.
- Principal Investigator
  
  UEDA Haruyasu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hyogo University of Health Sciences
Trafficking of immune-competent cells mediated by high endothelial venule-associated cell trafficking signals and regulation of innate and acquired immune responses.Principal Investigator
- Principal Investigator
  
  TANAKA Toshiyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hyogo University of Health Sciences
リンパ節特異的な細胞動員シグナルによる制御性細胞の組織特異的動員と自己応答性制御Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hyogo University of Health Sciences
腫瘍血管へ免疫細胞動員活性を誘導する生体プログラムの賦活化と抗腫瘍免疫監視の強化Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hyogo University of Health Sciences
  Osaka University
Stromal factors regulating tumor cell motility
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
L-セレクチン結合糖鎖の構造的多様性と機能的多義性の免疫細胞動態制御における意義Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
高内皮細静脈特異的な細胞動員シグナルによるリンパ球ホーミング制御と免疫監視の強化Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Adhesive interactions governing immune-cell trafficking across HEVs and its regulation by infectious stimulationPrincipal Investigator
- Principal Investigator
  
  TANAKA Toshiyuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
リンパ球ホーミングを支配する高内皮細静脈に特異的な細胞動員シグナルの形成と制御Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
感染により誘発されるリンパ節高内皮細静脈の機能変換とその獲得免疫成立における意義Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Molecular mechanisms of adhesive interactions between HEV and lymphocytes that regulate homeostatic lymphocyte homing.Principal Investigator
- Principal Investigator
  
  TANAKA Toshiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Role of leukocyte specific adaptor protein leupaxin in T cell migrationPrincipal Investigator
- Principal Investigator
  
  TANAKA Toshiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
セレクチン、CD44及びケモカイン結合性プロテオグリカン・バーシカンの糖鎖と機能
- Principal Investigator
  
  川島博人
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
白血球特異的パキシリン様蛋白質リューパキシンによる造血系腫瘍細胞の運動制御Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Identification and funs tonal analysis of novel molecules that regulate tumor cell motility
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
セレクチン、CD44の共通のリガンド・バーシカンの炎症細胞、癌細胞浸潤への関与
- Principal Investigator
  
  川島博人
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
リンパ節発生過程における高内皮細静脈を介したリンパ球集積の分子機構Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Molecular mechanisms underlying lymphocyte-specific cell trafficking into lymph nodes-Functional analysis of genes specifically expressed in high endothelial venules (HEV)
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
がん細胞の接着が誘発する血管内皮細胞間隙の開裂に関わるシグナル伝達分子の探索Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
遺伝子発現プロフィルを指標にしたリンパ節形成機構の解析Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
3'末端特異的cDNAライブラリを用いた免疫組織特異的分子の探索Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
IL2レセプターβ鎖トランスジェニックマウスを用いたIL2特異的シグナルの解析Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
接着分子による白血球、がん細胞と内皮細胞間相互作用とその分子機構
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
IL-2シグナルの組織特異性を決定する細胞内因子の解析Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Generation of a new mouse model for transplantation of human cells by utilizing an anti-IL-2 receptor beta chain monoclonal antibody
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute for Medical Science
ILー2レセプタ-の構造と機能の解析Principal Investigator
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
リンホカイン受容体の相互作用の解析
- Principal Investigator
  
  北村ふじ子
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] 免疫・炎症病態×治療Update2019
- Author(s)
  熊ノ郷淳、田中稔之、加納規資、織大祐、河合太郎、松本功、渡辺充、岡田正人、西出真之、目黒和行、中島裕史、岩部真人、山内敏正、岩部美紀、門脇孝、福原淳範、下村伊一郎、佐藤正大、西岡安彦、武田吉人
- Total Pages
  252
- Publisher
  南山堂
- ISBN
  9784525167813
- Data Source
  KAKENHI-PROJECT-18K07305
[Book] Encyclopedia of Immunobiology, Vol. 32016
- Author(s)
  Ratcliffe, M.J.H. (Editor in Chief) ; Tanaka T.
- Total Pages
  536
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-25460603
[Book] 標準生理学　第８版2014
- Author(s)
  田中稔之、大橋俊夫、北川誠一、石川義弘、本間研一、丸中良典、木村純子、瀬尾義輝、久保義弘、岡村康司、飯野正光、柚﨑通介、真鍋俊也、玉巻伸章、金子武嗣、河野憲二、泰羅雅登、吉村　惠、大森治紀、杉内友理子　他
- Total Pages
  1140
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25460603
[Journal Article] Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target.2021
- Author(s)
  Hayashi N, Yamasaki A, Ueda S, Okazaki S, Ohno Y, Tanaka T, Endo Y, Tomioka Y, Masuko K, Masuko T, Sugiura R.
- Journal Title
  
  Oncotarget
  
  Volume: 12 Issue: 13 Pages: 1256-1270
- DOI
  10.18632/oncotarget.27981
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07741, KAKENHI-PROJECT-20K16315, KAKENHI-PROJECT-19H03376, KAKENHI-PROJECT-21K07229, KAKENHI-PLANNED-18H05463
[Journal Article] Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage2020
- Author(s)
  Manabe E, Ito S, Ohno Y, Tanaka T, Naito Y, Sasaki N, Asakura M, Masuyama T, Ishihara M, Tsujino T.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 22023-22023
- DOI
  10.1038/s41598-020-79146-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08055, KAKENHI-PROJECT-18K07305
[Journal Article] Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow.2019
- Author(s)
  Ito S, Ohno Y, Tanaka T, Kobuchi S, Ayajiki K, Manabe E, Masuyama T, Jun-Ichi S, Tsujino T.
- Journal Title
  
  Renal Failure
  
  Volume: 41 Issue: 1 Pages: 284-293
- DOI
  10.1080/0886022x.2019.1597736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08055, KAKENHI-PROJECT-18K07305
[Journal Article] Differential regulation of the sphere formation and maintenance of cancer-initiating cells of malignant mesothelioma via CD44 and ALK4 signaling pathways.2018
- Author(s)
  Ohno Y, Shingyoku S, Miyake S, Tanaka A, Fudesaka S, Shimizu Y, Yoshifuji A, Yamawaki Y, Yoshida S, Tanaka S, Sakura K, Tanaka T.
- Journal Title
  
  Oncogene
  
  Volume: 37 Issue: 49 Pages: 6357-6367
- DOI
  10.1038/s41388-018-0405-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07305
[Journal Article] Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia.2015
- Author(s)
  Man CH, Fung TK, Wan H, Cher CY, Fan A, Ng N, Ho C, Wan TS, Tanaka T, So CW, Kwong YL, Leung AY.
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 25 Pages: 3928-3936
- DOI
  10.1182/blood-2014-06-580993
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460603
[Journal Article] Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis2013
- Author(s)
  Bai Z
- Journal Title
  
  J. Immunology
  
  Volume: 190 Issue: 5 Pages: 2036-2048
- DOI
  10.4049/jimmunol.1202025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191, KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-23790071, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24590252, KAKENHI-PLANNED-21121007, KAKENHI-ORGANIZER-22116001
[Journal Article] Dynamic changes in endothelial cell adhesion molecule nepmucin/CD300LG expression under physiological and pathological conditions.2013
- Author(s)
  Umemoto, E, Takeda, A., Jin, S., Luo, Z., Nakahogi, N., Hayasaka, H., Lee, C.M., Tanaka, T. & Miyasaka, M.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 12 Pages: 1-12
- DOI
  10.1371/journal.pone.0083681
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121007, KAKENHI-PROJECT-23659671, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24590252, KAKENHI-PROJECT-25460268, KAKENHI-PROJECT-25460603
[Journal Article] NIH3T3 cells overexpressing CD98 heavy chain resist early G1 arrest andapoptosis induced by serum starvation.2012
- Author(s)
  Hara K, Ueda S, Ohno Y, Tanaka T, Yagi H, Okazaki S, Kawahara R, Masayuki T, Enomoto T, Hashimoto Y, Masuko K, Masuko T.
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 8 Pages: 1460-1466
- DOI
  10.1111/j.1349-7006.2012.02304.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-22700889, KAKENHI-PROJECT-23370065
[Journal Article] Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse.2012
- Author(s)
  Bobbala D, Chen XL, Leblanc C, Mayhue M, Stankova J, Tanaka T, Chen YG, Ilangumaran S, Ramanathan S.
- Journal Title
  
  Diabetologia
  
  Volume: 55 Issue: 11 Pages: 3010-3020
- DOI
  10.1007/s00125-012-2675-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590440
[Journal Article] Constitutive Plasmacytoid Dendritic Cell Migration to the Splenic White Pulp Is Cooperatively Regulated by CCR7- and CXCR4-Mediated Signaling.2012
- Author(s)
  Umemoto, E.
- Journal Title
  
  J. Immunol.
  
  Volume: 189 Issue: 1 Pages: 191-199
- DOI
  10.4049/jimmunol.1200802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390096, KAKENHI-PROJECT-22590191, KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-23590570, KAKENHI-PLANNED-21121007, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003, KAKENHI-PLANNED-24111005
[Journal Article] Oncogenicity of L-type amino-acid transporter 1 (LAT1) revealed by targeted gene disruption in chicken DT40 cells : LAT1 is a promising molecular target for human cancer therapy2011
- Author(s)
  Ohkawa, M., Ohno, Y., Masuko, K., Takeuchi, A., Suda, K., Kubo, A., Kawahara, R., Okazaki, S., Tanaka, T., Saya, H., Seki, M., Enomoto, T., Yagi, H., Hashimoto, Y., Masuko, T.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 406 Issue: 4 Pages: 649-655
- DOI
  10.1016/j.bbrc.2011.02.135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-22700889
[Journal Article] Rap1 controls lymphocyte adhesion cascades and interstitial migration within lymph nodes in a RAPL-dependent and independent manner.2010
- Author(s)
  *Ebisuno, Y., *Katagiri, K., Katakai, T., Ueda, Y., Nemoto, T., Inada, H., Nabekura, J., Okada, T., Kannagi, R., Tanaka, T., Miyasaka, M., Hogg, N., Kinashi, T. (*equal contribution)
- Journal Title
  
  Blood 115
  
  Pages: 804-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] A LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin.2010
- Author(s)
  Tanaka, T., et al
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Pages: 363-368
- NAID
  10026587701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590440
[Journal Article] LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin.2010
- Author(s)
  Tanaka, T.
- Journal Title
  
  Canser Sci. 101
  
  Pages: 363-368
- NAID
  10026587701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] TIM-3 is a promising target to selec tively kill acute myeloid leukemia s tem cells2010
- Author(s)
  Kikushige Y, Shima T 他7名
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7巻 Issue: 6 Pages: 708-717
- DOI
  10.1016/j.stem.2010.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390295, KAKENHI-PROJECT-22249039, KAKENHI-PROJECT-22590440
[Journal Article] LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin.2010
- Author(s)
  Tanaka T, Moriwaki K, Murata S, Miyasaka M.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Issue: 2 Pages: 363-368
- DOI
  10.1111/j.1349-7006.2009.01398.x
- NAID
  10026587701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590440
[Journal Article] Natural killer cells target HCV core proteins during the innate immune response in HCV transgenic mice.2010
- Author(s)
  Satoh K, Takahashi H, Matsuda C, Tanaka T, Miyasaka M, Zeniya M, Kohara M.
- Journal Title
  
  J Med Virol
  
  Volume: 82 Issue: 9 Pages: 1545-1553
- DOI
  10.1002/jmv.21859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-22590748
[Journal Article] A LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin.2010
- Author(s)
  Tanaka, T., Moriwaki, K., Murata, S., Miyasaka, M.
- Journal Title
  
  Cancer Sci. 101
  
  Pages: 363-368
- NAID
  10026587701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] A LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin2010
- Author(s)
  Tanaka, T.et al
- Journal Title
  
  Cancer Sci. 101
  
  Pages: 363-368
- NAID
  10026587701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060028
[Journal Article] Chondroitin sulfate E fragments enhance CD44 cleavage and CD44-dependent motility in tumor cells.2008
- Author(s)
  Sugahara, K.N., Hirata, T., Tanaka, T., Ogino, S., Takeda, M., Terasawa, H., Shimada, I., Tamura, J., Ten Dam, G.B., Van Kuppevelt, T.H., Miyasaka, M.
- Journal Title
  
  Cancer Res. 68
  
  Pages: 7191-7199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Involvement of a lysophosphatidic-acid generating enzyme autotaxin in lymphocyte-endothelial cell interactions2008
- Author(s)
  Nakasaki, T., Tanaka, T.(equal contribution)
- Journal Title
  
  Am. J. Pathol 173
  
  Pages: 1566-1576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Nepmucin/CLM-9, an Ig domain-containing sialomucin in vascular endothelial cells, promotes lymphocyte transendothelial migration in vitro.2008
- Author(s)
  Jin, S., Umemoto, E., Tanaka, T., Shimomura, Y., Tohya, K., Kunizawa, K., Yang, B. -G., Jang, M.H., Hirata, T., Miyasaka, M.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 3018-3024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Involvement of a lysophosphatidic-acid generating enzyme autotaxin in lymphocyte-endothelial cell interactions.2008
- Author(s)
  *Nakasaki, T., *Tanaka, T., Okudaira, S., Hirosawa, M., Umemoto, E., Otani, K., Jin, S., Bai, Z., Hayasaka, H., Fukui, Y., Aozasa, K., Fujita, N., Tsuruo, T., Ozono, K., Aoki, J., Miyasaka, M. (*equal contribution)
- Journal Title
  
  Am. J. Pathol. 173
  
  Pages: 1566-1576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Binding of lymphoid chemokines to collagen IV that accumulates in the basal lamina of high endothelial venules; its implication in lymphocyte trafficking.2007
- Author(s)
  Yang, B. -G., Tanaka, T., Jang, M.H., Bai, Z., Hayasaka, H., Miyasaka, M.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 4376-4382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells-Molecular basis of their trafficking to lymphnodes.2007
- Author(s)
  #Matsutani, T., #Tanaka, T., et. al. (#equal contribution)
- Journal Title
  
  Int. Immunol. 19
  
  Pages: 1031-1037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015033
[Journal Article] Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells - Molecular basis of their trafficking to lymph nodes.2007
- Author(s)
  *Matsutani, T., *Tanaka, T., Tohya, K., Otani, K., Jang, M.H., Umemoto, E., Taniguchi, K., Hayasaka, H., Ueda, K., Miyasaka, M. (*equal contribution)
- Journal Title
  
  Int. Immunol. 19
  
  Pages: 1031-1037
- NAID
  10020107880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] CD43 collaborates with P-selectin glycoprotein ligand-1 to mediate E-selectin-dependent T cell migration into inflamed skin.2007
- Author(s)
  Matsumoto, M., Shigeta, A., Furukawa, Y., Tanaka, T., Miyasaka, M., Hirata, T.
- Journal Title
  
  J. Immunol. 178
  
  Pages: 2499-2506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells - Molecular basis of their trafficking to lymphnodes.2007
- Author(s)
  *Mautani, T.・*Tanaka, T.(*equal contribution)
- Journal Title
  
  lnt. lmmunol. 19
  
  Pages: 1031-1037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow.2006
- Author(s)
  Umemoto, E., Tanaka, T., Kanda, H., Jin, S., Tohya, K., Otani, K., Matsutani, T., Matsumoto, M., Ebisuno, Y., Jang, M.H., Fukuda, M., Hirata, T., Miyasaka, M.
- Journal Title
  
  J. Exp. Med. 203
  
  Pages: 1603-1614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  ^*Kanemitsu, N., ^*Ebisuno, Y., ^*Tanaka, T.(^*equal contribution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590432
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  ^*Kanemitsu, N., ^*Ebisuno, Y., ^*Tanaka, T.(^*equal contribution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Data Source
  KAKENHI-PROJECT-17046010
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  *Kanemitsu, N., *Ebisuno, Y., *Tanaka, T., Otani, K., Hayasaka, H., Kaisho, T., Akira, S., Katagiri, K., Kinashi, T., Fujita, N., Tsuruo, T., Miyasaka, M. (*equal contribution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  ^*Kanemitsu, N., ^*Ebisuno, Y., ^*Tanaka, T.(^*equal contribution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Data Source
  KAKENHI-PROJECT-17047025
[Journal Article] Invasive human pancreatic carcinoma cells adhere to endothelial tri-cellular corners and increase endothelial permeability.2005
- Author(s)
  Nakai, K., Tanaka, T., Murai, T., Ohguro, N., Tano, Y., Miyasaka, M.
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 766-773
- NAID
  10017091610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Review : Chemokines in tumor progression and metastasis.2005
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 317-322
- Data Source
  KAKENHI-PROJECT-17046010
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  ^*Kanemitsu, N., ^*Ebisuno, Y., ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Invasive human pancreatic carcinoma cells adhere to endothelial tri-cellular corners and increase endothelial permeability.2005
- Author(s)
  Nakai, K., ^#Tanaka, T.et al.(^#corresponding author)
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 766-773
- NAID
  10017091610
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590432
[Journal Article] Chemokines in tumor progression and metastasis.2005
- Author(s)
  Tanaka, T., Bai, Z., Srinoulprasert, Y., Yang, B. -G., Hayasaka, H., Miyasaka, M.: Review
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 317-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Invasive human pancreatic carcinoma cells adhere to endothelial tri-cellular corners and increase endothelial permeability.2005
- Author(s)
  Nakai, K., ^#Tanaka, T.et al.(^#corresponding author)
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 766-773
- NAID
  10017091610
- Data Source
  KAKENHI-PROJECT-17047025
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  ^*Kanemitsu, N., ^*Ebisuno, Y., ^*Tanaka, T.(^*equai contnbution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Data Source
  KAKENHI-PROJECT-17590432
[Journal Article] Review : Chemokines in tumor progression and metastasis.2005
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 317-322
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590432
[Journal Article] Review : Chemokines in tumor progression and metastasis.2005
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 317-322
- Data Source
  KAKENHI-PROJECT-17047025
[Journal Article] Invasive human pancreatic carcinoma cells adhere to endothelial tri-cellular corners and increase endothelial permeability.2005
- Author(s)
  Nakai, K., ^#Tanaka, T.et al.(^#corresponding author)
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 766-773
- NAID
  10017091610
- Data Source
  KAKENHI-PROJECT-17046010
[Journal Article] Review : Chemokines in tumor progression and metastasis.2005
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 317-322
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  ^*Kanemitsu, N., ^*Ebisuno, Y., Tanaka, T.(^*equal contribution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590432
[Journal Article] Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling.2004
- Author(s)
  Kanda, H., Tanaka, T.et al.(equal contribution)
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 1265-1274
- NAID
  10013503954
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling.2004
- Author(s)
  ^*Kanda, H., ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 1265-1274
- NAID
  10013503954
- Data Source
  KAKENHI-PROJECT-16043235
[Journal Article] Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling.2004
- Author(s)
  ^*Kanda, H., ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 1265-1274
- NAID
  10013503954
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Review : Molecular determinants controlling homeostatic recirculation and tissue-specific trafficking of lymphocytes.2004
- Author(s)
  Tanaka, T.et al.
- Journal Title
  
  Int.Arch.Allergy Immunol. 134
  
  Pages: 120-134
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] Review : Molecular determinants controlling homeostatic recirculation and tissue-specific trafficking of lymphocytes.2004
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Int.Arch.Allergy Immunol. 134
  
  Pages: 120-134
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] Molecular determinants controlling homeostatic recirculation and tissue-specific trafficking of lymphocytes.2004
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Int.Arch.Allergy Immunol. 134
  
  Pages: 120-134
- Data Source
  KAKENHI-PROJECT-16043235
[Journal Article] Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling.2004
- Author(s)
  ^*Kanda, H., ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 1265-1274
- NAID
  10013503954
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling.2004
- Author(s)
  ^★Kanda, H., ^★Tanaka, T.et al.(^★equal contribution)
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 1265-1274
- NAID
  10013503954
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] Lymphocyte trafficking across high endothelial venules: Dogmas and Enigmas.2004
- Author(s)
  Miyasaka, M., Tanaka, T.
- Journal Title
  
  Nat.Rev.Immunol. 4
  
  Pages: 360-370
- Data Source
  KAKENHI-PROJECT-16043235
[Journal Article] Molecular determinants controlling homeostatic recirculation and tissue-specific trafficking of lymphocytes.2004
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Int.Arch.Allergy Immunol. 134
  
  Pages: 120-134
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Molecular determinants controlling homeostatic recirculation and tissue-specific trafficking of lymphocytes.2004
- Author(s)
  Tanaka, T.et al.
- Journal Title
  
  Int.Arch.Allergy Immunol. 134
  
  Pages: 120-134
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Lymphocyte trafficking across high endothelial venules : Dogmas and Enigmas.2004
- Author(s)
  Miyasaka, M., Tanaka, T.
- Journal Title
  
  Nat.Rev Immunol. 4
  
  Pages: 360-370
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Lymphocyte trafficking across high endothelial venules : Dogmas and Enigmas.2004
- Author(s)
  Miyasaka, M., Tanaka, T.
- Journal Title
  
  Nat.Rev.Immunol. 4
  
  Pages: 360-370
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Lymphocyte trafficking across high endothelial venules : Dogmas and Enigmas.2004
- Author(s)
  Miyasaka, M., Tanaka, T.
- Journal Title
  
  Nat.Rev.Immunol. 4
  
  Pages: 360-370
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] Endomucin, a sialomucin expressed in high endothelial venules, supports L-selection-mediated rolling.2004
- Author(s)
  ^*Kanda, H., ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 1265-1274
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind the inflammatory but not lymphoid chemokines and is dispensable for lymphocyte homing under physiological conditions.2003
- Author(s)
  ^*Kashiwazaki, M., ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  Int.Immunol. 15
  
  Pages: 1219-1227
- NAID
  10014343160
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind the inflammatory but not lymphoid chemokines and is dispensable for lymphocyte homing under physiological conditions.2003
- Author(s)
  ^★Kashiwazaki, M., ^★Tanaka, T.et al.(^★equal contribution)
- Journal Title
  
  Int.Immunol. 15
  
  Pages: 1219-1227
- NAID
  10014343160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind the inflammatory but not lymphoid chemokines and is dispensable for lymphocyte homing under physiological conditions.2003
- Author(s)
  ^*Kashiwazaki, M., ^*Tanaka, et al.(^*equal contribution)
- Journal Title
  
  Int.Immunol. 15
  
  Pages: 1219-1227
- NAID
  10014343160
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Cutting Edge : The B cell chemokine CXCL13/B-lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules.2003
- Author(s)
  Ebisuno, Y., Tanaka, T.et al.(equal contribution)
- Journal Title
  
  J.Immunol. 171
  
  Pages: 1642-1646
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Cutting Edge : The B cell chemokine CXCL13/B-lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules.2003
- Author(s)
  ^*Ebisuno, Y., ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  J.Immunol. 171
  
  Pages: 1642-1646
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind the inflammatory but not lymphoid chemokines and is dispensable for lymphocyte homing under physiological conditions.2003
- Author(s)
  Kashiwazaki, M., Tanaka, T.et al.(equal contribution)
- Journal Title
  
  Int.Immunol. 15
  
  Pages: 1219-1227
- NAID
  10014343160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Expression of chemokines and chemokine binding molecules in high endothelial venules that mediate lymphocyte homing into lymph nodes and Peyer's patches.2003
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Microcirculation Annual 19
  
  Pages: 3-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Expression of Chemokines and chemokine binding molecules in high endothelial venules that mediate lymphocyte homing into lymph nodes and Peyer's patches.2003
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Microcirculatron Annual 19
  
  Pages: 3-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Cutting Edge : The B cell chemokine CXCL13/B-lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules.2003
- Author(s)
  ^★Ebisuno, Y., ^★Tanaka, T.et al.(^★equal contribution)
- Journal Title
  
  J.Immunol. 171
  
  Pages: 1642-1646
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219211
[Journal Article] Cutting Edge : The B cell chemokine CXCL13/B-lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules.2003
- Author(s)
  ^*Ebisuno, Y, ^*Tanaka, T.et al.(^*equal contribution)
- Journal Title
  
  J.Immunol. 171
  
  Pages: 1642-1646
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Chemokines in tumor progression and metastasis.
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Cancer Sci. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Journal Article] Chemokines in tumor progression and metastasis.
- Author(s)
  Tanaka, T. et al.
- Journal Title
  
  Cancer Sci. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590437
[Presentation] IL-18-primed NK cells recruit dendritic cells and potentiate tumor therapy mediated by PD-1 blockade.2023
- Author(s)
  Ohno Y, Tanaka T.
- Organizer
  JSICR/MMCB 2023 Joint Symposium
- Data Source
  KAKENHI-PROJECT-21K07229
[Presentation] IL-18-primed NK cells recruit dendritic cells and potentiate tumor therapy mediated by PD-1 blockade2023
- Author(s)
  Yoshiya Ohno and Toshiyuki Tanaka
- Organizer
  JSICR/MMCB 2023 Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06706
[Presentation] IL-18 recruits CD103+ dendritic cells via NK cell activation and potentiates immunotherapy mediated by PD-1 blockade2021
- Author(s)
  大野喜也、田中稔之
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K07741
[Presentation] IL-18 recruits CD103+ dendritic cells via NK cell activation and potentiates immunotherapy mediated by PD-1 blockade2021
- Author(s)
  Yoshiya Ohno & Toshiyuki Tanaka
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-21K07229
[Presentation] IL-18と免疫チェックポイント阻害薬によって誘導される抗腫瘍免疫における免疫細胞のダイナミクス2018
- Author(s)
  大野喜也、西村嘉泰、河野真己、加戸祥揮、有本奈緒子、岡村春樹、田中稔之
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18K07305
[Presentation] Activin-AシグナルとCD44シグナルによる悪性中皮腫癌幹細胞の制御機構2018
- Author(s)
  大野喜也、新玉紗理奈、三宅咲奈、田中亜弥、筆坂世奈、清水雄太、吉藤愛、山脇優輝、佐倉千萬、田中稔之
- Organizer
  第68回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-18K07305
[Presentation] Anti-tumor immune cell dynamics during immunotherapy with anti-PD-1 antibody and IL-18.2018
- Author(s)
  Ohno Y, Okamura H, Tanaka T.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07305
[Presentation] IL-18と抗PD-1抗体が誘導する抗腫瘍免疫における免疫細胞動態2018
- Author(s)
  大野喜也、西村嘉泰、河野真己、加戸祥揮、有本奈緒子、岡村春樹、田中稔之
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07305
[Presentation] 低酸素環境が造腫瘍性を示すCD133陽性悪性中皮腫細胞の維持に寄与する.2015
- Author(s)
  大野喜也、田中稔之
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] THP-1 macrophage-like cells were induced to differentiate towards an M2-like phenotype by human malignant mesothelioma cells and enhanced the expression of stem cell-associated markers in the tumor cells.2015
- Author(s)
  Ohno Y, Tanaka T.
- Organizer
  International Conference of Cancer Immunotherapy and Macrophages 2015
- Place of Presentation
  Ito International Research Center（東京都文京区）
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] Activin-ALK4 axisは悪性中皮腫細胞株MSTOのALDHhigh細胞を維持し、造腫瘍性を高める.2015
- Author(s)
  大野喜也、田中稔之
- Organizer
  第24回日本がん転移学会学術集会・総会
- Place of Presentation
  シティプラザ大阪（大阪府大阪市）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] The autotaxin/lysophosphatidic acid axis regulates lymphocyte extravasation at lymph node high endothelial venules.2012
- Author(s)
  Bai Z, Cai L, Umemoto E, Tohya K, Takeda A, Hata E, Hayasaka H, Tanaka T, Miyasaka M.
- Organizer
  Keystone Symposia Conference on Chemokines and Leukocyte Trafficking.
- Place of Presentation
  Colorado, USA.
- Year and Date
  2012-01-09
- Data Source
  KAKENHI-PROJECT-22590440
[Presentation] The study of mesothelioma cancer stem cells using in vivo proliferation and sphere culture models.2012
- Author(s)
  Ohno Y, Ueda H, Tanaka T.
- Organizer
  The21st Annual Meeting of the Japanese CancerAssociation for Metastasis Research.
- Place of Presentation
  Oriental Hotel Hiroshima (Hiroshima)
- Year and Date
  2012-07-13
- Data Source
  KAKENHI-PROJECT-22590440
[Presentation] Stem cell-like propertiesin CD133+ cells isolated from xenografted human malignant mesothelioma in immunodeficient mice.2012
- Author(s)
  Ohno Y, Tanaka T.
- Organizer
  The 71st Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Royton Sapporo (Sapporo)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22590440
[Presentation] Constitutive pDC migration to the splenic white pulp is cooperatively regulated by CCR7 ligands and CXCL12.2011
- Author(s)
  Umemoto E, Ikeno T, Verjan Garcia N, Hayasaka H, Bai Z, Jang, M.H, Tanaka T, Miyasaka M.
- Organizer
  The40th annual meeting of the Japanese Society for Immunology.
- Place of Presentation
  Makuhari Messe (Chiba).
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-22590440
[Presentation] Nepmucin mediates uptake of apoptotic cells in the endothelial cells of high endothelial venules.2010
- Author(s)
  Umemoto, E., Kunizawa, K., Jin, S.,Yonekura, S., Jang, M.H., Tanaka, T, Miyasaka, M.
- Organizer
  14th International Congress of Immunology.
- Place of Presentation
  Kobe International Conference Center (Kob.
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-22590440
[Presentation] Spheroid forming malignant mesothelioma cells showed cancer stem cell-like properties and spontaneously produced proinflammatory cytokines
- Author(s)
  大野喜也、牛尾明雅、田中亜弥、筆坂世奈、新玉紗理奈、三宅咲奈、上田晴康、田中稔之
- Organizer
  第21回マクロファージ分子細胞生物学国際シンポジウム（MMCB2013）
- Place of Presentation
  都市センターホテル（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] HA-CD44 axis was required for formation of malignant mesothelioma spheroids and maintenance of CSC-like ALDHhigh cells
- Author(s)
  大野喜也、田中稔之
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] 悪性中皮腫のスフェロイド形成と癌幹細胞様細胞におけるActivinの役割
- Author(s)
  清水雄太、大野喜也、田中稔之
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] CD44依存的なスフェロイド形成はactivin産生を介してALDH発現を亢進させる.
- Author(s)
  大野喜也、田中稔之
- Organizer
  第23回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール（石川県金沢市）
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] 悪性中皮腫のスフェロイド形成とALDH陽性癌幹細胞様細胞におけるActivinの役割
- Author(s)
  清水雄太、大野喜也、田中稔之
- Organizer
  第63回日本薬学会近畿支部総会・大会
- Place of Presentation
  同志社女子大学（京都府京田辺市）
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] TGFシグナルによる悪性中皮腫スフェロイドの形成とALDH陽性癌幹細胞様細胞の制御
- Author(s)
  大野喜也、筆坂世奈、清水雄太、三宅咲奈、田中稔之
- Organizer
  第22回日本がん転移学会学術集会・総会
- Place of Presentation
  ホテルブエナビスタ（長野県松本市）
- Data Source
  KAKENHI-PROJECT-25460603
[Presentation] CD44-dependent signals and pro- and anti-inflammatory cytokines differentially regulate spheroid formation and maintenance of cancer stem-like cells in malignant mesothelioma cells.
- Author(s)
  大野喜也、田中稔之
- Organizer
  第22回マクロファージ分子細胞生物学国際シンポジウム（MMCB2014）
- Place of Presentation
  神戸商工会議所（兵庫県神戸市）
- Year and Date
  2014-06-02 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-25460603

1. MIYASAKA Masayuki (50064613)

# of Collaborated Projects: 11 results

# of Collaborated Products: 14 results
2. OONO Yoshiya (40509155)

# of Collaborated Projects: 9 results

# of Collaborated Products: 23 results
3. KAWASHIMA Hiroto (50260336)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. UEDA Haruyasu (10330458)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
5. KITAMURA Fujiko (90124453)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MURAI Toshiyuki (20311756)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. HIRATA Takako (00346199)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
8. HAYASAKA Haruko (70379246)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. UMEMOTO Eui (90452440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. JANG Myoung-ho (70420453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. BAI Zhongbin (10512840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. VERJAN-GARCIA Noel (90533216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAWA Yukifumi (10040172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. UEYAMA Yoshihito (30072408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. URANO Kouji (80213510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 後藤満一 (50162160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岡村春樹 (60111043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. NAITO Yoshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 関政幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 伊藤都裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 辻野健

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 増山理

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

tanaka toshiyuki 田中 稔之

TANAKA Toshiyuki 田中 稔之

田中 稔之 タナカ トシユキ

Research Projects

Research Products

Co-Researchers

実臨床に基づく併用薬の抗腫瘍免疫応答の修飾機序の解明と癌免疫治療の最適化への応用Principal Investigator

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Principal Investigator

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IL-18-induced type I immune response and regulation of immune checkpoints by tumor neoantigensPrincipal Investigator

Principal Investigator

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Principal Investigator

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Regulation of immune-checkpoint by IL-18 and its application to cancer immunotherapyPrincipal Investigator

Principal Investigator

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Review Section

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Tissue-specific trafficking of immune-competent cells mediated by lymph node-associated cell trafficking signals and regulation of immune-responses towards self components.Principal Investigator

Principal Investigator

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Principal Investigator

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Trafficking of immune-competent cells mediated by high endothelial venule-associated cell trafficking signals and regulation of innate and acquired immune responses.Principal Investigator

Principal Investigator

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リンパ節特異的な細胞動員シグナルによる制御性細胞の組織特異的動員と自己応答性制御Principal Investigator

Principal Investigator

Project Period (FY)

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腫瘍血管へ免疫細胞動員活性を誘導する生体プログラムの賦活化と抗腫瘍免疫監視の強化Principal Investigator

Principal Investigator

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Principal Investigator

Project Period (FY)

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Research Institution

L-セレクチン結合糖鎖の構造的多様性と機能的多義性の免疫細胞動態制御における意義Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

高内皮細静脈特異的な細胞動員シグナルによるリンパ球ホーミング制御と免疫監視の強化Principal Investigator

Principal Investigator

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tanaka toshiyuki 田中稔之

TANAKA Toshiyuki 田中稔之

田中稔之タナカトシユキ