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NAGAI Sonoko  長井 苑子

ORCIDConnect your ORCID iD *help
Researcher Number 30217955
Other IDs
Affiliation (based on the past Project Information) *help 1998 – 2002: Kyoto University, Graduate School, Department of Reep Med., 医学研究科, 助教授
1991 – 1997: 京都大学, 胸部疾患研究所, 助教授
1992: Chest Disease Research Institute Associate Professor., 助教授
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine
Except Principal Investigator
Respiratory organ internal medicine
Keywords
Principal Investigator
Sarcoidosis / サルコイドーシス / 間質性肺炎 / Tリンパ球 / HPLC / IL-1 / apoptosis / TGFB / T-lymphocyte / protease … More / cytokine / fibroblast / collagen-vascular disease / interstitial pneumonia / Th3リンパ球 / Th2リンパ球 / Th1リンパ球 / 免疫反応・炎症反応 / 気道および肺胞領域 / アポトーシス / TGFβ / プロテアーゼ / サイトカイン / 線維芽細胞 / 膠原病 / Interstitial Pneumonia associated with collagen vascular disease / Bronchialveolar lavage fluid / cellular infiltration / Pulmonary Fibrosis / Surgical Biopsy / Interstitial Pneumonia / 臨床経過・予後 / 特発性間質性肺炎 / 線維化病変 / 炎症性病変 / 膠原病性間質性肺炎 / 膠原病間質性肺炎 / 気管支肺胞洗浄液 / 炎症細胞浸潤 / 線維化 / 外科的肺生検 / angiotensis II receptor / activetal V.D / IL-Iβ / IL-I receptor antagonist / BALF manophge / Proguostic factors / Deteriolation / Chronicity / マクロファージ / 骨密度 / 性差 / 慢性化の指標 / マクロファーシ / ACE / 難治化 / 慢性化 / イオン化カルシウム / 活性型ビタミンD / IL-1β / IL-1レセプターアンタゴニスト / アンギオテンシンII受容体 / BALFマクロファージ / 予後の指標 / 病勢の指標 / TCR V gene / Monoclonal Antibody / Flow cytometry / Swedish / Japanese / HLA-typing / T cell antigenic receptor (TCR) / HLAB61(40) / TCRVβ22、CD8陽性T細胞 / スウエーデン人 / TCR V遺伝子発現 / モノクローナル抗体パネル / フローサイトメトリー / スウェーデン人 / 日本人 / HLAタイピング / TCR(T細胞抗原受容体) / Idiopathic Pulmonary Fibrosis / PCR / IL-1 receptor antagonist / IL-1 inhibitory factor / Alveolar macrophage / 慢性炎症 / レセプタ-・アンタゴニスト / インタ-ロイキン1抑制物質 / インタ-ロイキン1 / 肺胞マクロファ-ジ / 1L-1レセプターアンタゴニスト / 1L-1抑制物質 / 1L-1 / 特発性肺線維症 / PCR法 / IL-1レセプター・アンタゴニスト / IL-1制御物質 / 肺胞マクロファージ … More
Except Principal Investigator
IPF / 特発性肺線維症 / ACE / Fibronectin / 線維芽細胞 / NSIP / 喫煙 / PDGF-BB / PDGF-AA / apoptosis / 肺胞上皮細胞 / 平滑筋増生 / BOOP / 遺伝子発現 / Capsaicin cough sensitivity / Substance P / ACE gene polymorphism / cough / カプサイシン / 咳受容体感受性 / カプサイシン咳受容体感受性 / サブスタンスP / ACE遺伝子多型 / 咳嗽 / smoking / proteinase / endogenous steroid / 疾患感受性 / 家族集積 / glucocorticoid / α-SM actin / 形質変換機構 / 線維化 / 間質性肺炎 / RT-PCR / 成長因子 / サイトカイン / プロテアーゼ / 内因性ステロイド / IGF-β / Contraction / Fibroblast / Pulmonary Fibrosis / TGF-β / 収縮能 / 肺線維症 / Oxidant / Cigarette Smoking / Matrix Metalloproteinase-3 / Tissue Inhibitors of Metalloproteinase-3 / Alveolar cells / OxidunA / Apoptosis / 契煙 / 蛋白分解酵素阻害物質 / 蛋白分解酵素 / オキシダント / アポプトーシス / MMP-3 / TIMP-3 / Interstitial macrophages / Ashcroft's fibrosis scoro / Platelet-derived / Smooth muscle proliferation / Clubbed fingers / Idiopathic pulmonary fibrosis / 線維化病変内マクロファージ / 抗CD68抗体 / 抗PDGF-BBモノクローナル抗体 / 抗PDGF-AAモノクローナル抗体 / 血小板由来増殖因子(PDGF) / 線維化病変内平滑筋増生 / Aschroftの線維化病変指数 / 間質性マクロファージ / Aschcroftの線維化病変指数 / 血小板由来成長因子 / ばち状指 / proliferation / fibroblast / fibrosis / inflammation / 気管支肺胞洗浄液 / 肺線維化 / 肺傷害 / 接着因子 / 表面抗原 / リポコルチン遺伝子 / 可溶性IL-2 / II型肺胞上皮細胞 / アポトーシス / 肺線維芽細胞 / CD-8 positive cell / CD-4 positive cell / CD-3 positive cell / Type III collagen / Type I collagen / smooth muscle proliferation / idiopathic pulmonary fibrosis / 免疫組織化学 / コラ-ゲン / CD8陽性Tリンパ球 / CD4陽性Tリンパ球 / 炎症細胞 / 特発性BOOP / 特発性UIP / 線維化肺疾患 / CD-8陽性細胞 / CD-4陽性細胞 / CD-3陽性細胞 / III型コラーゲン / I型コラーゲン / gene expression / Angiotensin II receptor / T lymphocyte alveolitis / accessory cell / BALF macrophage / Angiotensin Converting Enzyme / epithelioid cell granuloma / Sarcoidosis / TNFα / ILー1β / アンジオテンインII / 慢性化 / サルコイド-ジス / 類上皮細胞内芽腫 / アンギオテンシンIIレセプター / Tリンパ球性肺胞炎 / アクセサリー細胞 / BALFマクロファージ / アンギオテンシン変換酵素 / 類上皮細胞肉芽腫 / サルコイドーシス Less
  • Research Projects

    (13 results)
  • Co-Researchers

    (9 People)
  •  Factors related to capsaicin cough sensitivity in healthy subject

    • Principal Investigator
      MURO Shigeo, 新實 彰男
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Protective mechanisms in inflammatory lung diseases at airway and alveolar areaPrincipal Investigator

    • Principal Investigator
      NAGAI Sonoko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  The relationship between the desease susceptibility and the regulation of gene expression in the transformation of fibroblast

    • Principal Investigator
      TSUKINO Mitsuhiro
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Inflammation and Fibrosis in patients with Interstitial PneumoniaPrincipal Investigator

    • Principal Investigator
      NAGAI Sonoko, 泉 孝英
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Contractility of fibroblasts derived from long fibrosis

    • Principal Investigator
      MIO Tadashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Proteinase and Proteinase inhibitor production of Alveolar cells and the effects of cigarette smoking

    • Principal Investigator
      NISHIMURA Koichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Pathophysiological and Logical Clinical Study in patients with Sarcoidosm Prognoitic factorsPrincipal Investigator

    • Principal Investigator
      NAGAI Sonoko
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  A pathogenetlc study on smooth muscle proliferation in the fibrotlc changes of idiopathic pulmonary fibrosis

    • Principal Investigator
      KITAICHI Masanori
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Multifactorial analysis of chronicity and pathogenesis in patients with sarcoidosisPrincipal Investigator

    • Principal Investigator
      NAGAI Sonoko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular biological approach to the pathophysiological Processes in the lungs of idiopathic pulmonary fibrosis

    • Principal Investigator
      IZUMI Takateru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Immunological and moleculogenetic study of chronic sarcoidosis

    • Principal Investigator
      IZUMI Takateru
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Immunohistologic and stereohistolog c research on the fibrotic processes of idiopathic fibrosing pulmonary diseases

    • Principal Investigator
      KITAICHI Masanori
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  •  Characterization of IL-1 inhibitor released from alveolar macrophage and evaluation of chronic inflammation in lungs.Principal Investigator

    • Principal Investigator
      NAGAI Sonoko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      KYOTO UNIVERSITY
  • 1.  KITAICHI Masanori (00161464)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  MIO Tadashi (90243097)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  IZUMI Takateru (80027101)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  SATAKE Norio (50252515)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  NISHIMURA Koichi (80243096)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  NIIMI Akio (30252513)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MURO Shigeo (60344454)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  TSUKINO Mitsuhiro (40293956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  CHIN Kazuo (90197640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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