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MARUYAMA Toshiyuki  丸山 稔之

ORCIDConnect your ORCID iD *help
Researcher Number 30219571
Other IDs
Affiliation (based on the past Project Information) *help 2006: The University of Tokyo, Faculty of Medicine, Lecturer, 大学院・医学系研究科, 講師
2006: 東京大学, 大学院医学系研究科, 講師
2005: 東京大学, 医学部附属病院, 講師
2000 – 2004: 東京大学, 大学院・医学系研究科, 講師
2001: 東京大学, 大学院・医学系研究科医学部, 講師 … More
1996 – 1999: 東京大学, 医学部・附属病院, 助手
1997: 東京大学, 医学部附属病院, 助手
1996: Faculty of Med, Dept of Med(2), University of Tokyo, Assistant, 医学部(附属病院), 助手
1995: 東京大学, 医学部・付属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology
Except Principal Investigator
Gastroenterology / Gastroenterology
Keywords
Principal Investigator
cytokine / mutation / HBV-DNA / transgenic mouse / tolerance / HBV / immune suppression therapy / 免疫応答 / HCV / coagulated volume … More / development of liver tumors / tumor necrosis / microbubble / HIFU / 肝臓癌モデルrat / 経門脈的投与 / 焼灼体積 / 肺臓癌モデルrat / パルミチン酸 / 腫瘍壊死 / マイクロバブル / 強力集束超音波発信装置 / 核酸変異 / 抗原提示 / トランスジェニックマウス / fulminant hepatitis / IFNγ / IL1 / TNFα / 塩基配列 / HBVキャリアー / 免疫抑制剤 / 劇症肝炎 / fulminant hepatits / mouse / prognostic ralue / IgG subtype / interferon / vaccine / peptide / ペプタイト / C型肝炎 / IgGサブクラス / エペトープ / マウス / 治療効果 / IgGサブタイプ / インターフェロン / ワクチン / ペプタイド / 細胞周期 / 肝発癌 / コア蛋白 / C型肝炎ウイルス … More
Except Principal Investigator
HCV / アンギオスタチン / C型肝炎ウイルス / C型肝炎 / liver cancer / RNA interference / 肝臓癌 / RNA干渉 / receptor / 受容体 / liver endothelial cells / Angiostain / 腫瘍血管 / 肝臓内皮細胞 / viral receptor / hepatitis C virus / レセプター / ウイルスレセプター / coagulation & fibrinolysis / plasminogen / hepatocellular carcinoma / angiostatin / 血液凝固線溶系 / プラスミノーゲン / 肝細胞癌 / DNA vaccine / hepatocarcinogenesis / hepatitis / core protein / envelope protein / transgenic mice / hepatitis C / 唾液腺炎 / シェ-グレン症候群 / DNAワクチン / 肝発癌 / 肝炎 / コア蛋白 / エンベロープ蛋白 / トランスジェニックマウス / Stress protein / Autoantibody / Autoimmune hepatitis / 抗ストレス 抗体 / HSP 70 / ELISA法 / ストレス蛋白 / 自己抗体 / 自己免疫性肝炎 Less
  • Research Projects

    (12 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (20 People)
  •  Fundamental study for therapy of liver cancers based on RNA interference

    • Principal Investigator
      MITSUI Hiroshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Using microbubbles to increase the destruction of liver tumors by high-intensity focused ultrasoundPrincipal Investigator

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Identification and analysis of co-receptor for hepatitis C virus

    • Principal Investigator
      MITSUI Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  The comparison of virus genome and immune reaction between asymptomatic carriers and chronic hepatitis patients infected with HBV.Principal Investigator

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  The study of tumor vessel growth inhibiton Angiostatin, new mechanism of action and clinical application

    • Principal Investigator
      MITSUI Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Identification of hepatitis C virus receptor on human hepatocytes and regulation of the viral infection

    • Principal Investigator
      MITUSI Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  The mechanism which causes fulminant hepatic failure after immune suppression therapy on HBV carrier patientsPrincipal Investigator

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Characterization of the anti-angiogenic factors in hepatocellular carcinoma10301102

    • Principal Investigator
      MAEKAWA Hisato
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Investigation for the development of vaccine against hepatitis C virusPrincipal Investigator

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  肝発癌におけるC型肝炎コア蛋白の遺伝子発現修飾作用とその細胞内結合蛋白の同定Principal Investigator

    • Principal Investigator
      丸山 稔之
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  DEVELOPMENT OF HEPATITIS THERAPY AND VACCINE USING HEPATITIS C VIRUS TRANSGENIC MICE

    • Principal Investigator
      KOIKE Kazuhiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      TOKYO UNIVERSITY
  •  Immunological significance of stress procein in pathogenesis of autoimmune hepatitis

    • Principal Investigator
      NOSAKA Kazuo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tokyo

All 2006 2005 2004 2003 2001 Other

All Journal Article Book

  • [Book] In Proceedings of 3rd International Symposium on Therapeutic Ultrasound2005

    • Author(s)
      Kaneko Y, Maruyama T, et al.
    • Publisher
      The effect of microbubbles as a heat transducer.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Microbubble-induced increase in ablation of liver tumors by high-intensity focused ultrasound2006

    • Author(s)
      Hanajiri K, Maruyama T, Mitsui H, et al.
    • Journal Title

      Hepatology Research 36

      Pages: 308-314

    • NAID

      10018639873

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T, Mitsui M, et al.
    • Journal Title

      European Radiology 14

      Pages: 1415-1420

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein thrombus.2005

    • Author(s)
      Hanajiri K, Mitsui H, Maruyama T, Kondo Y, Shiina S, Omata M, Nakagawa K.
    • Journal Title

      Journal of Gastroenterology. 40

      Pages: 1005-1006

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T, Takegami K, Watanabe T, Mitsui M, Hanajiri K, Nagawa H, Matsumoto Y.
    • Journal Title

      European Radiology 15

      Pages: 1415-1420

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] 18F-FDGPET for hepatocellular carcinoma presenting with portal vein thrombus.2005

    • Author(s)
      Hanajiri K, Mitsui H, Maruyama T, Kondo Y, Shiina S, Omata M, Nakagawa K
    • Journal Title

      Journal of Gastroenterology. 2005.40

      Pages: 1005-1006

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein tumor thrombus.2005

    • Author(s)
      Hanajiri K, Mitsui H, Maruyama T, et al.
    • Journal Title

      Journal of Gastroenterology 40

      Pages: 1005-1006

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein tumor thrombus2005

    • Author(s)
      Hanajiri K, Mitsui H, Maruyama T, et al.
    • Journal Title

      J Gastroenterol 40

      Pages: 1005-1006

    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Comparison of Optison and MRX-133 microbubble contrast agent in improving heating and coagulation volume efficiency of high intensity focused ultrasound.2005

    • Author(s)
      Takegami K, Kaneko K, Watanabe T, Maruyama T, Matsumoto Y, Nagawa H.
    • Journal Title

      Radiology 237

      Pages: 132-136

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T, et al.
    • Journal Title

      European Radiology 15

      Pages: 1415-1420

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Erythrocytes, as well as microbubble contrast agents, are important factors in improving thermal and therapeutic effects of high-intensity focused ultrasound.2005

    • Author(s)
      Takegami K, Kaneko K, Watanabe T, Maruyama T, Matsumoto Y, Nagawa H.
    • Journal Title

      Ultrasound in Medicine and Biology 31

      Pages: 385-390

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Use of a minobuble agent to increase the effect of high in tensity focused ultrasound on liver tissuce.2005

    • Author(s)
      Kanaeko Y, Maruyama T, Mitsui H, et al.
    • Journal Title

      Eur Radiol 92

      Pages: 55-62

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Use of a microbuble agent to increase the effects of high intensity focused ultrasound on time tissue2005

    • Author(s)
      Kaneko Y, Maruyama T, … Mitsui H, et al.
    • Journal Title

      Eur Radiol 92

      Pages: 55-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T, Mitsui M, et al.
    • Journal Title

      European Radiology 15

      Pages: 1415-1420

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Use of a microbuble agent to increase the effect of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T,... Mitsui H, et al.
    • Journal Title

      Eur Radiol 92

      Pages: 55-62

    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Polyacrylamide gel containing egg white as new model for irradiation experiments using focused ultrasound.2004

    • Author(s)
      Takegami K, Kaneko K, Watanabe T, Maruyama T, Matsumoto Y, Nagawa H.
    • Journal Title

      Ultrasound in Medicine and Biology 30

      Pages: 1419-1422

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Clinical efficacy and toxicity of gefitinib in patients with lung cancer2003

    • Author(s)
      Mitsui H, … Maruyama T, et al.
    • Journal Title

      Lancet 361

      Pages: 1993-1993

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Anti-HBS antibodies produced after live transplantation : from the donor or the recipient?2003

    • Author(s)
      Maruyama T, Mitsui H, et al.
    • Journal Title

      Hepatology 38

      Pages: 271-272

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Anti-Hβs antibodies produces after liver transplantation : from the donor or the recipient ?2003

    • Author(s)
      Maruyama T, Mitsui H, et al.
    • Journal Title

      Hepatology 38

      Pages: 271-272

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] The effect of microbubbles as a heat transducer.2003

    • Author(s)
      Kaneko Y., Higaki T., Maruyama T., Matsumoto Y.
    • Journal Title

      In Proceedings of 3rd International Symposium on Therapeutic Ultrasound; Lyon, France

      Pages: 55-60

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Clinical efficacy and toxicity of gefitinib in patients with lung cancer.2003

    • Author(s)
      Mitsui H, Nakajima J, Maruyama T, Hanajiri K, Omata M.
    • Journal Title

      Lancet 361

      Pages: 1993-1993

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Clinical efficacy and toxicity of gefitinib in patients with lung cancer2003

    • Author(s)
      Mitsui H, Maruyama T, et al.
    • Journal Title

      Lancet 361

      Pages: 1993-1993

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Anti-HBs antibodies produced after liver transplantation : from the donor or the recipient?2003

    • Author(s)
      Maruyama T., Mitsui H., Hanajir Ki, Sugawara Y, Imamura H, Makuuchi M.
    • Journal Title

      Hepatology 38

      Pages: 271-272

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] Anti-HBs antibodies produced after liver transplantation : from the donor or the recipient?2003

    • Author(s)
      Maruyama T, et al.
    • Journal Title

      Hepatology 38

      Pages: 271-72

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390228
  • [Journal Article] IgGi anti-P2 as a marker of response to interferon in patients with chronic hepatitis C.2001

    • Author(s)
      Hirayama M, Maruyama T, Mitsui H, Maekawa H, Yamada H, Hashimoto N, Koike K, Kimura S, Yasuda K, Iino S, Green J.
    • Journal Title

      Clin Exp Immunol. 126(1)

      Pages: 92-100

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13670496
  • [Journal Article] The MEK1-ERK map kinase pathway and the PI 3-kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver cancer cells.2001

    • Author(s)
      Mitsui H, Takuwa N, Maruyama T, Maekawa H, Hirayama M, Sawatari T, Hashimoto N, Takuwa Y, Kimura S.
    • Journal Title

      Int J Cancer. 92(1)

      Pages: 55-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13670496
  • [Journal Article] Esophageal smooth muscle tumor in a 25-year-old woman with congenital malformations.2001

    • Author(s)
      Maekawa H, Tanaka N, Hashimoto N, Yamada H, Mitsui H, Ikeda H, Maruyama T, Mori M, Nagawa H, Kimura S.
    • Journal Title

      J Gastroenterol. 36(10)

      Pages: 700-703

    • NAID

      50000970489

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13670496
  • [Journal Article] Use of a microbulluasent to increare the effects of high intensity tocured ultrasound on liver tissue

    • Author(s)
      Kaneko Y, Maruyama T, Mitsui H, et al.
    • Journal Title

      European Ladiology (in press)

    • Data Source
      KAKENHI-PROJECT-15590623
  • 1.  MITSUI Hiroshi (30239280)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 16 results
  • 2.  KOIKE Kazuhiko (80240703)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  MAEKAWA Hisato (10301102)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MORIYA Kyouji (00272550)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  SAKATA Youichi (40129028)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  YOTSUYANAGI Hiroshi (30251234)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  NOSAKA Kazuo (70150274)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YAMADA Haruki (70174729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TSUKAMOTO Kazuhisa (20251233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TOMA Shigeto (50207528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  AOKI Katsunori (40291322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MATSUMOTO Yoichiro (60111473)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 13.  TAKAGI Shu (30272371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NANGAKU Masaomi (90311620)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ISHIBASHI Kotaro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SHINTANI Yoshizumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  UMEMURA Shinichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  温 活寛
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HAN Kk
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  潘 活寛
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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