Sakai Akiko 境晶子

… Alternative Names

SAKAI Akiko 境晶子

境晶子サカイアキコ

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Researcher Number	30225750
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 大阪医科薬科大学, 医学部, 講師 2012 – 2020: 大阪医科大学, 医学部, 講師 2007 – 2011: 大阪医科大学, 医学部, 助教 2003 – 2005: 大阪医科大学, 医学部, 助手 1992: 大阪医科大学, 教養部, 助手
Review Section/Research Field	Principal Investigator Biomolecular chemistry / Living organism molecular science / Applied genomics Except Principal Investigator Applied genomics / Molecular biology
Keywords	Principal Investigator オリゴマー構造 / HSPB1 / 抗癌剤耐性 / リン酸化 / サイトケラチン / プロテオミクス / 熱ショック蛋白質 / 生体分子 / HSP1B / 翻訳後修飾 … More / 耐性獲得マーカー / オリゴマー化 / 等電点電気泳動法 / MALDI / Replica blotting / 等電点二次元電気泳動法 / 低酸素ストレス … More Except Principal Investigator 定常期 / 大腸菌 / RFHR二次元電気泳動 / RFHR法 / リボソーム / rat liver / E.coli / IPG method / RFHR method / two dimensional electrophoresis / proteomics / プロテオーム解析 / 等電点法 / O'Farrell法 / 二次元電気泳動法 / ヒト血球 / ヒト血清 / 質量分析 / 対数期 / 等電点 / 蛋白質 / ラット肝 / IPG法 / 2次元電気泳動法 / プロテオミクス / 膜局在 / 翻訳因子 / リボソームサイクル / 極低温電子顕微鏡 / 100Sリボソーム / ストレス応答 / 大腸がん / 塩基性蛋白質 / プロテオーム / 抗癌剤抵抗性 / 胃癌 / 大腸癌 / 筋型酵素 / 肝型酵素 / cDNA塩基配列 / ラット脳 / フルクトース2.6二リン酸 / フルクトース6リン酸2キナーゼ Less

Elucidation of structure-function relationship of multidrug resistance-associated protein HSPB1 and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  SAKAI Akiko
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Osaka Medical and Pharmaceutical University
Elucidation of structure-function relationship of HSPB1 in anticancer drug resistance mechanismPrincipal Investigator
- Principal Investigator
  
  SAKAI AKIKO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Osaka Medical College
Studies on the molecular mechanism of 5-fluorouracil response proteins using a proteomic approachPrincipal Investigator
- Principal Investigator
  
  SAKAI Akiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka Medical College
Proteomic analysis of oxidative stress-responsive proteins in metabolic syndromePrincipal Investigator
- Principal Investigator
  
  SAKAI Akiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied genomics
- Research Institution
  Osaka Medical College
Elucidation of E.coli 100S ribosome structure and formation mechanisms
- Principal Investigator
  
  YOSHIDA Hideji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka Medical College
Human proteomics by the high-powered RFHR 2D PAGE for detection of protein changes resistant to anticancer agents
- Principal Investigator
  
  WADA Akira
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Yoshida Biological Laboratry, Bio-informatics section
  Osaka Medical College
One protein/cell proteomics by the high power RFHR-2D-PAGE
- Principal Investigator
  
  WADA Akira
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Osaka Medical College
フルクトース2.6二燐酸合成酵素に起因する脳と腎臓の臓器特異的な糖代謝調節
- Principal Investigator
  
  FURUYA Eisuke
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Institution
  Osaka Medical College

All 2020 2018 2017 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Reaction of threonine synthase with the substrate analogue 2-amino-5-phosphonopentanoate: Implications into the proton transfer at the active site2020
- Author(s)
  Y. Machida, T. Murakawa, A. Sakai, M. Shoji, Y. Shigeta, H. Hayashi
- Journal Title
  
  Biochemistry
  
  Volume: 167 Issue: 4 Pages: 357-364
- DOI
  10.1093/jb/mvz100
- NAID
  40022210984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05047, KAKENHI-PROJECT-17K01955
[Journal Article] Comparative proteomic analysis of paclitaxel resistance-related proteins in human breast cancer cell lines.2017
- Author(s)
  藤岡大也
- Journal Title
  
  ONCOLOGY LETTERS
  
  Volume: 13 Issue: 1 Pages: 289-295
- DOI
  10.3892/ol.2016.5455
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08950, KAKENHI-PROJECT-26350963
[Journal Article] Down-regulation of collagen I biosynthesis in intestinal epithelial cells exposed to indomethacin: a comparative proteome analysis.2014
- Author(s)
  Edogawa S, Sakai A et al
- Journal Title
  
  Journal of Proteomics
  
  Volume: 103 Pages: 35-46
- DOI
  10.1016/j.jprot.2014.03.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510267, KAKENHI-PROJECT-26350963
[Journal Article] Identification of DNA mismatch recognition proteins in the thermophilic bacterium Geobacillus stearothermophilus.2012
- Author(s)
  Matsunaga F, Sakai A, Mochizuki S, Minami K, Inatsu S.
- Journal Title
  
  Bulletin of Toyo College of Food Technology
  
  Volume: 1 Pages: 9-15
- NAID
  40019606330
- Data Source
  KAKENHI-PROJECT-23510267
[Journal Article] Identification of phosphorylated serine-15 and -82 residues of HSPB1 in 5-fluorouracil-resistant colorectal cancer cells by proteomics.2012
- Author(s)
  Sakai A, Otani M, Miyamoto A, Yoshida H, Furuya E, Tanigawa N.
- Journal Title
  
  Journal of Proteomics
  
  Volume: 75 Issue: 3 Pages: 806-818
- DOI
  10.1016/j.jprot.2011.09.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510267
[Journal Article] YqjD is an inner membrane protein associated with stationary-phase ribosomes in Escherichia coli.2012
- Author(s)
  Hideji Yoshida, Yasushi Maki, Shou Furuike , Akiko Sakai, Masami Ueta, Akira Wada.
- Journal Title
  
  J Bacteriol.
  
  Volume: 194 Issue: 16 Pages: 4173-4183
- DOI
  10.1128/jb.00396-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510210, KAKENHI-PROJECT-23510267
[Journal Article] Phosphoproteome Profiling Using a Fluorescent Phosphosensor Dye in Two-Dimensional Polyacrylamide Gel Electrophoresis.2011
- Author(s)
  Otani M, Taniguchi T, Sakai A, Seta J, Kadoyama K, Nakamura-Hirota T, Matsuyama S, Sano K, Takano M
- Journal Title
  
  Appl.Biochem.Biotechnol (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510192
[Journal Article] Phosphoproteome profiling using a fluorescent phosphosensor dye in two-dimensional polyacrylamide gel electrophoresis.2011
- Author(s)
  Otani M, Taniguchi T, Sakai A, et al.
- Journal Title
  
  Appl Biochem Biotechnol
  
  Volume: 164 Issue: 6 Pages: 804-818
- DOI
  10.1007/s12010-011-9175-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510267
[Journal Article] Comparative proteomic analysis of the ribosomes in 5-fluorouracil resistance of a human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis.2010
- Author(s)
  Kimura K, Wada A, Ueta M, Ogata A, Tanaka S, Sakai A, Yoshida H, Fushitani H, Miyamoto A, Fukushima M, Uchiumi T, Tanigawa N
- Journal Title
  
  Int.J.Oncol 37
  
  Pages: 1271-1278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510192
[Journal Article] Peroxisome proliferation activation receptor alpha modulation of Ca2+-regulated exocytosis via arachidonic acid in guinea-pig antral mucous cells.2010
- Author(s)
  Sawabe Y, Shimamoto C, Sakai A, Kuwabara H, Saad AH, Nakano T, Takitani K, Tamai H, Mori H, Marunaka Y, Nakahari T
- Journal Title
  
  Exp Physiol 95
  
  Pages: 858-868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510192
[Journal Article] 薬剤耐性を獲得した大腸癌細胞株におけるプロテオーム解析2010
- Author(s)
  境晶子
- Journal Title
  
  大阪医科大学雑誌 69
  
  Pages: 39-40
- Data Source
  KAKENHI-PROJECT-20510192
[Journal Article] Activities of E. coll ribosomes in IF3 and RMF change to prepare 100S ribosome formation on entering the stationary growth phase2009
- Author(s)
  H. Yoshida, M. Ueta, Y. Maki, A. Sakai, A. Wada
- Journal Title
  
  Genes to Cells 14
  
  Pages: 271-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570167
[Journal Article] Proteomic analysis of the basic proteins in 5-fluorouracil resistance of human colon cancer cell line using the RFHR 2D PAGE.2009
- Author(s)
  Satoru Tanaka, Akiko Sakai, Kousei Kimura, Hideji Yoshida, Hideo Fushitani, Akihiko Ogata, Akiko Miyamoto, Masakazu Fukushima, Akira Wada, Nobuhiko Tanigawa
- Journal Title
  
  International J. Oncology 33
  
  Pages: 361-370
- Data Source
  KAKENHI-PROJECT-19310132
[Journal Article] Activities of Escherichia coliribosomes in IF3 and RMF change to prepare 100S ribosome formation on entering the stationary growth phase.2009
- Author(s)
  Yoshida H, Ueta M, Maki Y, Sakai A, Wada A
- Journal Title
  
  Genes to Cells 14
  
  Pages: 271-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510192
[Journal Article] Use of a phosphosensor dye in proteomic analysis of human mutant tautransgenic mice.2009
- Author(s)
  Takano M, Otani M, Sakai A, Kadoyama K, Matsuyama S, Matsumoto A, Takenokuchi M, Sumida M, Taniguchi T
- Journal Title
  
  Molecular neuroscience 20
  
  Pages: 1648-1653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510192
[Journal Article] Activities of E.coli ribosomes in IF3 and RMF change to prepare 100S ribosome formation on entering the stationary growth phase2009
- Author(s)
  Hideji Yoshida, Masami Ueta, Yasushi Maki, Akiko Sakai, Akira Wada
- Journal Title
  
  Genes to Cells vol.14
  
  Pages: 271-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570167
[Journal Article] Proteomic analysis of the basic proteins in 5-fluorouracil resistance of human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis.2008
- Author(s)
  Tanaka S, Sakai A, Kimura K, Yoshida H, Fushitani H, Ogata A, Miyamoto A, Fukushima M, Wada A, Tanigawa N
- Journal Title
  
  Int.J.Oncol 33
  
  Pages: 361-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510192
[Journal Article] Angiotensin-II receptor blocker exerts cardioprotection in diabetic rats exposed to hypoxia2006
- Author(s)
  S.Inamoto, T.Hayashi, A.Sakai, E.Furuya, Y.Kitaura et al.
- Journal Title
  
  Circ J. (In press)
- NAID
  110004750159
- Data Source
  KAKENHI-PROJECT-15310142
[Journal Article] Monochloroacetic acid inhibits liver gluconeogenesis by inactivation glyceraldehydes-3-phosphate dehydrogenase2005
- Author(s)
  Akiko Sakai, Hiroshi Shimizu, Koishi Kono, Eisuke Furuya
- Journal Title
  
  Chemical Research in Toxicology 18・2
  
  Pages: 277-282
- Data Source
  KAKENHI-PROJECT-15310142
[Journal Article] Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehydes-3-phosphate dehydrogenase2005
- Author(s)
  A.Sakai
- Journal Title
  
  Chem.Res.Toxicol. 18
  
  Pages: 277-282
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310142
[Journal Article] Monochloroacetic acid inhibits liver gluconeogenes is by inactivating glyceraldehydes-3-phosphate dehydrogenase2005
- Author(s)
  A.Sakai
- Journal Title
  
  Chem.Res.Toxicol. 18
  
  Pages: 277-282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310142
[Journal Article] Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceral dehydes-3-phosphate dehydrogenase2005
- Author(s)
  A.Sakai, H.Shimizu, K.Kono, E.Furuya
- Journal Title
  
  Chem.Res.Toxicol. 18
  
  Pages: 277-282
- Data Source
  KAKENHI-PROJECT-15310142
[Journal Article] Itaconate reduces visceral fat by inhibiting fructose 2,6-bisphosphate synthesis in rat liver2004
- Author(s)
  A.Sakai
- Journal Title
  
  NUTRITION 20
  
  Pages: 997-1002
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310142
[Presentation] トレオニン合成酵素の反応機構―予期せぬアルジミン中間体の出現とその意義2018
- Author(s)
  町田康博，村川武志，境　晶子，林　秀行
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K01955
[Presentation] 抗癌剤5-FU耐性株におけるHSPB1のリン酸化とオリゴマー構造2011
- Author(s)
  境　晶子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜国際会議場
- Data Source
  KAKENHI-PROJECT-23510267
[Presentation] 薬剤耐性を獲得した大腸癌細胞におけるプロテオーム解析2009
- Author(s)
  境晶子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシィフィコ横浜(神奈川)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20510192
[Presentation] 薬剤耐性を獲得した大腸癌細胞におけるプロテオーム解析2009
- Author(s)
  境晶子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィッコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20510192
[Presentation] Structural analysis of 100S ribosome by cryoEM : tRNA binding2009
- Author(s)
  吉田秀司, 加藤貴之, 牧泰史, 古池晶, 上田雅美, 境晶子, 和田明, 難波啓一
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] GraFix法により安定化した100SリボソームのcryoEMによる構造解析2009
- Author(s)
  吉田秀司, 加藤貴之, 牧泰史, 古池晶, 上田雅美, 境晶子, 和田明, 難波啓一
- Organizer
  第11回 RNAミーティング
- Place of Presentation
  新潟市朱鷺メッセ(新潟)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] GraFix法により安定化した100SリボソームのcryoEMによる構造解析2009
- Author(s)
  吉田秀司、加藤貴之、牧泰史、古池晶、上田雅美、境晶子、和田明、難波啓一
- Organizer
  第11回RNAミーティング
- Place of Presentation
  新潟市朱鷺メッセ
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] Structural analysis of 100S ribosome by cryo-EM2009
- Author(s)
  加藤貴之, 吉田秀司, 牧泰史, 古池晶, 上田雅美, 境晶子, 和田明, 難波啓一
- Organizer
  第47回日本生物物理学会年会
- Place of Presentation
  アスティ徳島(徳島)
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] Structural analysis of 100S ribosome by cryoEM : tRNA binding2009
- Author(s)
  Hideji Yoshida, Takayuki Kato, Yasushi Maki, Shou Furuike, Masami Ueta, Akiko Sakai, Akira Wada, Keiichi Namba
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19310132
[Presentation] Structural analysis of 100S ribosome by cryoEM using a GraFix method2009
- Author(s)
  Takayuki Kato, Hideji Yoshida, Yasushi Maki, Shou Furuike, Masami Ueta, Akiko Sakai, Akira Wada, Keiichi Namba
- Organizer
  第11回RNAミーティング
- Place of Presentation
  新潟市朱鷺メッセ
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-19310132
[Presentation] Structual analysis of 100S ribosome by cryoEM : tRNA binding.2009
- Author(s)
  Hideji Yoshida, Takayuki Kato, Yasushi Maki, Shou Furuike, Masami Ueta, Akiko Sakai, Akira Wada, Keiichi Namba
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19310132
[Presentation] 大腸癌細胞株における薬剤耐性獲得のプロテオーム解析-O-GlcNAc修飾に注目して2008
- Author(s)
  境晶子
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会の合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20510192
[Presentation] E.coli YqjD expresses during the stationary phase and binds to ribosomes2008
- Author(s)
  Hideji Yoshida, Yasushi Maki, Masami Ueta, Akiko Sakai, Akira Wada
- Organizer
  RNA2008 Thirteenth annual meeting of the RNA society
- Place of Presentation
  ベルリン(ドイツ)
- Year and Date
  2008-08-01
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] E. coli YqjD expresses during the stationary phase and binds to ribosomes2008
- Author(s)
  H. Yoshida, Y. Maki, M. Ueta, A. Sakai, A. Wada
- Organizer
  RNA2008 Thirteenth annual meeting of the RNA society
- Place of Presentation
  ベルリン(ドイツ)
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] 内膜およびリボソームに結合する大腸菌蛋白質YqjDの機能解析2008
- Author(s)
  吉田秀司, 牧泰史, 境晶子, 上田雅美, 和田明
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会)
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] 大腸菌膜結合性蛋白質YqjDは定常期に発現してリボソームに結合する2008
- Author(s)
  吉田秀司, 牧泰史, 境晶子, 上田雅美, 和田明
- Organizer
  第10回RNAミーティング
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-20570167
[Presentation] 100sリボソームとif3の関係2007
- Author(s)
  吉田秀司、上田雅美、牧泰史、境晶子、和田明
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19310132
[Presentation] 抗癌剤耐性株における熱ショック蛋白質HSPB1の翻訳後修飾とオリゴマー構造
- Author(s)
  境晶子，林秀行
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26350963
[Presentation] 抗癌剤耐性株における熱ショック蛋白質HSPB1の翻訳後修飾とオリゴマー構造
- Author(s)
  境晶子，林秀行
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-23510267

1. YOSHIDA Hideji (60288735)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. TANAKA Satoru (50595741)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. FURUYA Eisuke (00028523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WADA Akira (80025387)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. MAKI Yasushi (60401733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
6. WADA Chieko (10175698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. UETA Masami (30512511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. TANIGAWA Nobuhiko (00111956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HAYASHI Tetsuya (30257852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 谷川允彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 重田育照

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakai Akiko 境 晶子

SAKAI Akiko 境 晶子

境 晶子 サカイ アキコ

Research Projects

Research Products

Co-Researchers

Elucidation of structure-function relationship of multidrug resistance-associated protein HSPB1 and its clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of structure-function relationship of HSPB1 in anticancer drug resistance mechanismPrincipal Investigator

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Studies on the molecular mechanism of 5-fluorouracil response proteins using a proteomic approachPrincipal Investigator

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Proteomic analysis of oxidative stress-responsive proteins in metabolic syndromePrincipal Investigator

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Elucidation of E.coli 100S ribosome structure and formation mechanisms

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Human proteomics by the high-powered RFHR 2D PAGE for detection of protein changes resistant to anticancer agents

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One protein/cell proteomics by the high power RFHR-2D-PAGE

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フルクトース2.6二燐酸合成酵素に起因する脳と腎臓の臓器特異的な糖代謝調節

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[Journal Article] Reaction of threonine synthase with the substrate analogue 2-amino-5-phosphonopentanoate: Implications into the proton transfer at the active site2020

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NAID

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[Journal Article] Comparative proteomic analysis of paclitaxel resistance-related proteins in human breast cancer cell lines.2017

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[Journal Article] Down-regulation of collagen I biosynthesis in intestinal epithelial cells exposed to indomethacin: a comparative proteome analysis.2014

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[Journal Article] Identification of DNA mismatch recognition proteins in the thermophilic bacterium Geobacillus stearothermophilus.2012

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NAID

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[Journal Article] Identification of phosphorylated serine-15 and -82 residues of HSPB1 in 5-fluorouracil-resistant colorectal cancer cells by proteomics.2012

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[Journal Article] YqjD is an inner membrane protein associated with stationary-phase ribosomes in Escherichia coli.2012

Sakai Akiko 境晶子

SAKAI Akiko 境晶子

境晶子サカイアキコ