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TSUBOKAWA HIROSHI  坪川 宏

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TSUBOKAWA Hiroshi  坪川 宏

坪川 宏  ツボカワ ヒロシ

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Researcher Number 30227467
Other IDs
External Links
Affiliation (Current) 2025: 東北福祉大学, 健康科学部, 教授
Affiliation (based on the past Project Information) *help 2012 – 2014: 東北福祉大学, 健康科学部, 教授
2013: 東北福祉大学, 健康学部, 教授
2008 – 2009: 東北福祉大学, 健康科学部, 教授
2007: Tohoku University, 大学院・情報科学研究科, 教授
2006: 東北大学, 大学院情報科学研究科, 教授 … More
2005: 東北大学, 大学院・情報科学研究科, 教授
2000 – 2002: 岡崎国立共同研究機構, 生理学研究所, 助教授
1998: 自治医科大学, 医学部, 講師
1997: 自治医科大学, 医学部, 助手
1993 – 1994: 自治医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Neuroscience in general / 神経・脳内生理学
Except Principal Investigator
Educational psychology / Endocrinology / Biological Sciences / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords
Principal Investigator
海馬 / 樹状突起 / PKC / 情報処理 / パッチクランプ / 可塑性 / シナプス / backpropagation / 錐体細胞 / グルタミン酸受容体 … More / 虚血性神経細胞死 / スライスパッチクランプ / Brain science / Neurophysiology / Neuronal excitability / Calcium / Hippocampus / Imaging / Intracellular signaling / 脳科学 / 神経生理学 / 興奮性調節 / カルシウムイオン / イメージング / 細胞内情報伝達系 / 脳スライス / カナビノイド / Backpropagation / DSI / カノビノイド / 脳・神経 / 生理学 / 生体分子 / 神経科学 / シグナル伝達 / GABA / Gタンパク / コリン作働性受容体 / CaMKII / 細胞内カルシウム / 興奮性 / JSTX / 細胞内情報伝達 … More
Except Principal Investigator
心拍 / 育児教育 / NIRS / 脳活動 / 非言語情報 / 青年期 / 親性の発達 / IDS(対乳児発話) / 心理的反応 / 生理的反応 / 脳血流反応 / 脳機能計測 / 音響分析 / IDS / 親性発達 / 若年成人 / 表情認知 / 乳児 / NIRS / プロラクチン放出ペプチド / マウス / ラット / 電気生理 / 自律神経 / ペプチド / 延髄 / CRF / バゾプレシン / 神経ペプチド / 脳幹部 / 副腎皮質ホルモン / 視床下部 / ストレス / ノルアドレナリン / 活動電位 / 逆行性伝播 / カルシウム / プロスタグランジン / COX-2 / DSI / 2-AG / 細胞内シグナル伝達 / カナビノイド / 樹状突起 / 海馬 / 電気刺激 / Tuj1 / MAP2 / siRNA / パルス電気刺激 / NMDA受容体 / Caチャネル / Naチャネル / パッチクランプ / Notch / 間葉系幹細胞 / 神経細胞 Less
  • Research Projects

    (11 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (10 People)
  •  Regional brain responses and psychological bases in young adults to emotional infant stimuli.

    • Principal Investigator
      NIWANO Katsuko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Educational psychology
    • Research Institution
      Tohoku Fukushi University
  •  Regulatory mechanism for processing acute stress responses in the hypothalamus by prolacin-releasing peptide

    • Principal Investigator
      ITOI Keiichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Tohoku University
  •  樹状突起活動電位の生理学的役割に関する研究

    • Principal Investigator
      中尾 光之
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  間葉系幹細胞の一過性notch発現制御による神経細胞分化誘導の研究

    • Principal Investigator
      永富 良一
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Tohoku University
  •  樹状突起活動電位の生理学的役割に関する研究Principal Investigator

    • Principal Investigator
      坪川 宏
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  樹状突起活動電位の生理学的役割に関する研究Principal Investigator

    • Principal Investigator
      坪川 宏
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  細胞内シグナル伝達系による中枢ニューロンの興奮性調節メカニズムPrincipal Investigator

    • Principal Investigator
      坪川 宏
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Okazaki National Research Institutes
  •  Study on the function of intracellular signaling by visualization of enzyme activitiesPrincipal Investigator

    • Principal Investigator
      TSUBOKAWA Hiroshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      神経・脳内生理学
    • Research Institution
      Okazaki National Research Institutes
  •  イメージング法を用いた神経細胞樹状突起の興奮性制御メカニズムの解明Principal Investigator

    • Principal Investigator
      坪川 宏
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neuroscience in general
    • Research Institution
      Jichi Medical University
  •  スライスパッチクランプ記録法による虚血性神経細胞死のメカニズムに関する研究Principal Investigator

    • Principal Investigator
      坪川 宏
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neuroscience in general
    • Research Institution
      Jichi Medical University
  •  スライスパッチクランプ記録法による虚血性神経細胞死のメカニズムに関する研究Principal Investigator

    • Principal Investigator
      坪川 宏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neuroscience in general
    • Research Institution
      Jichi Medical University

All 2014 2012 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] 若年成人の対乳児発話表出時における脳反応 :近赤外線分光法による検討2014

    • Author(s)
      庭野賀津子・田邊素子・窪田美穂子・佐藤洋介・坪川宏
    • Journal Title

      感性福祉研究所年報

      Volume: 15

    • NAID

      40020171641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24530831
  • [Journal Article] 乳児の泣き顔に対する大学生の脳血流反応の 予備的検討2014

    • Author(s)
      田邊素子・庭野賀津子・佐藤洋介・坪川宏
    • Journal Title

      感性福祉研究所年報

      Volume: 15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24530831
  • [Journal Article] Generaton of corticotropin-releasing factor (CRF)-Venus knock-in mouse for studying the regulatory mechanism of CRF neurons in the paraventricular nucleus of the hypothalamus.2012

    • Author(s)
      Sugimoto N, Fuse T, Tsubokawa H, Yamazaki M, Abe M, Natsume R, Uchida K, Das G, Sakimura K, Itoi K
    • Journal Title

      Abs Ann Meetin Soc Neurosci

      Volume: 279 Pages: 11-11

    • Data Source
      KAKENHI-PROJECT-23591343
  • [Journal Article] Nonlinear-microscopy optical-pulse sources based on mode-locked semiconductor lasers2008

    • Author(s)
      H.Yokoyama, A.Sato, H.C.Guo, K.Sato, M.Mure, H.Tsubokawa
    • Journal Title

      Opt Express 16

      Pages: 17752-17758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20021001
  • [Journal Article] Electric pulse stimulation induces NMDA glutamate receptor mRNA in NIH3T3 mouse fibroblasts2008

    • Author(s)
      S.Okutsu, H.Hatakeyama, M.Kanzaki, H.Tsubokawa, R.Nagatomi
    • Journal Title

      Tohoku J Exp Med. 215

      Pages: 181-187

    • NAID

      10024168277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20021001
  • [Journal Article] Endocannabinoid signaling triggered by NMDA receptor-mediated calcium entry into rat hippocampal neurons.2007

    • Author(s)
      Ohno-Shosaku T, Hashimotodani Y, Ano M, Takeda S, Tsubokawa H, Kano M
    • Journal Title

      Journal of Physiology 15

      Pages: 407-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18021003
  • [Journal Article] Two-photon bioimaging utilizing supercontimuum light generated by a high-peak-power picosecond semiconductor laser source.2007

    • Author(s)
      Yokoyama H, Tsubokawa H, Guo HC, Shikata J, Mure M, Sato K, Takashima K, Kashiwagi K, Saito N, Taniguchi H, Ito H.
    • Journal Title

      Journal of Biomedical Optics 12

      Pages: 54019-54019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18021003
  • [Journal Article] Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.2006

    • Author(s)
      Wettschureck, N., van der Stelt, M., Tsubokawa, H., Krestel, H., Moers, A., Petrosino, S., Schutz, G., Di Marzo, V., Offermanns, S.
    • Journal Title

      Molecular and Cellular Biology 26

      Pages: 5888-5894

    • Data Source
      KAKENHI-PROJECT-18021003
  • [Journal Article] Phospholipase Cbeta Serves as a Coincidence Detector through Its Ca(2+) Dependency for Triggering Retrograde Endocannabinoid Signal.2005

    • Author(s)
      Hashimotodani Y, Ohno-Shosaku T, Tsubokawa H, Ogata H, Emoto K, Maejima, T, Araishi K, Shin HS, Kano M.
    • Journal Title

      Neuron 45

      Pages: 257-268

    • Data Source
      KAKENHI-PROJECT-17023005
  • [Journal Article] Hippocalcin-deficient mice display a deficit in cAMP response element-binding protein activation associated with impaired spatial and associative memory.2005

    • Author(s)
      Kobayashi M, Masaki T, Hori K, Masuo Y, Miyamoto M, Tsubokawa H, Noguchi H, Nomura M, Takamatsu K.
    • Journal Title

      Neuroscience 133

      Pages: 471-484

    • Data Source
      KAKENHI-PROJECT-17023005
  • [Presentation] Generaton of corticotropin-releasing factor (CRF)-Venus knock-in mouse for studying the regulatory mechanism of CRF neurons in the paraventricular nucleus of the hypothalamus2012

    • Author(s)
      Sugimoto N, Fuse T, Tsubokawa H, Yamazaki M, Abe M, Natsume R, Uchida K, Das G, Sakimura K, Itoi K
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-23591343
  • [Presentation] CRF-Venusノックインマウスを用いたCRFニューロン調節メカニズムの検討2012

    • Author(s)
      杉本直哉、布施俊光、坪川宏、山崎真弥、阿部学、夏目里恵、内田克哉、Gopal Das、岡野悠太郎、崎村建司、井樋慶一
    • Organizer
      第39回日本神経内分泌学会学術集会
    • Place of Presentation
      北九州
    • Year and Date
      2012-09-28
    • Data Source
      KAKENHI-PROJECT-23591343
  • [Presentation] Contribution of calcium-induced calcium release for propagation of YPKC translocation along the dendrites of cerebellar purkinje cell2009

    • Author(s)
      N.Katayama, N.Sakai, N.Saito, M.Nakao, H.Tsubokawa
    • Organizer
      日本生理学会
    • Place of Presentation
      京都市
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-20021001
  • [Presentation] Calcium-dependent dynamics of the PKCy in the cerebellar Purkinje cells2008

    • Author(s)
      片山統裕, 斉藤尚亮, 横山弘之, 坪川宏
    • Organizer
      第23回生体・生理工学シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2008-09-29
    • Data Source
      KAKENHI-PROJECT-20021001
  • [Presentation] 中枢ニューロン樹状突起におけるシグナル伝達系の時空間ダイナミクス2008

    • Author(s)
      片山統裕, 飽傑, 辛島彰洋, 中尾光之, 坪川宏
    • Organizer
      第47回日本生体医工学大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20021001
  • [Presentation] Active propagation of Na^+ spike in dendrite induces cannabinoid-receptor dependent suppression of GABAergic response in hippocampal CA1 neurons.2007

    • Author(s)
      S. TAKEDA, Y. FUJII, H. TSUBOKAWA
    • Organizer
      The 37th annual meeting of the Society for Neuroscience
    • Place of Presentation
      アメリカ合衆国サンディエゴ市
    • Year and Date
      2007-11-04
    • Data Source
      KAKENHI-PROJECT-18021003
  • [Presentation] Frequency-dependent response property of the dendrites in the hippocampal CA1 pyramidal cells.2007

    • Author(s)
      H. WATANABE, H. TSUBOKAWA, T. AIHARA, M. TSUKADA
    • Organizer
      第30回日本神経科学学会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2007-09-11
    • Data Source
      KAKENHI-PROJECT-18021003
  • [Presentation] Frequency-dependent signal processing in the apical dendrites in the hippocampal CA1 pyramidal neurons.2007

    • Author(s)
      H. WATANABE, H. TSUBOKAWA, T. AIHARA, M. TSUKADA
    • Organizer
      The 37th annual meeting of the Society for Neuroscience
    • Place of Presentation
      アメリカ合衆国サンディエゴ市
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-18021003
  • [Presentation] Information Processing in the Hippocampal Neuron by Active Dendrite2007

    • Author(s)
      Hiroshi Tsubokawa
    • Organizer
      The 4th Joint Forum for Dialogue with Regional Industri al Partners
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-18021003
  • [Presentation] CRF-Venusノックインマウスを用いたCRFニューロン調節メカニズムの検討.

    • Author(s)
      杉本直哉、布施俊光、坪川宏、山崎真弥、阿部学、夏目里恵、内田克哉、Gopal Das、岡野悠太郎、崎村建司、井樋慶一
    • Organizer
      第39回日本神経内分泌学会学術集会
    • Place of Presentation
      北九州国際会議場,北九州
    • Data Source
      KAKENHI-PROJECT-23591343
  • [Presentation] Generaton of corticotropin-releasing factor (CRF)-Venus knock-in mouse for studying the regulatory mechanism of CRF neurons in the paraventricular nucleus of the hypothalamus.

    • Author(s)
      Sugimoto N, Fuse T, Tsubokawa H, Yamazaki M, Abe M, Natsume R, Uchida K, Das G, Sakimura K, Itoi K
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans, LA, USA
    • Data Source
      KAKENHI-PROJECT-23591343
  • [Presentation] Development of CRF-Venus nock-in mouse for visualization of CRF neurons: a tool for studying cellular mechanisms and local circuitry regulating CRF neurons.

    • Author(s)
      Itoi K, Fuse T, Sugimoto N, Tsubokawa H, Yamazaki M, Abe M, Natsume R, Das G, Uchida K, Sakimura K
    • Organizer
      The 3rd Meeting of the Japan Branch of the International Neuropeptide Society
    • Place of Presentation
      Kitakyushu, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591343
  • 1.  ITOI Keiichi (60232427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  FUSE Toshimitsu (50401039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  UCHIDA Katsuya (40344709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  SAKIMURA Kenji (40162325)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  NIWANO Katsuko (30458202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  TANABE Motoko (30513618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  OHUCHI Mayumi (20296015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KUBOTA Mihoko (20275605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  永富 良一 (20208028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  中尾 光之 (20172265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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