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SHIMADA Hiroko  島田 博子

ORCIDConnect your ORCID iD *help
… Alternative Names

SUGAYA Hi  菅谷 博子

島田 博子(菅谷 博子)  シマダ ヒロコ(スガヤ ヒロコ)

島田 慱子  シマダ ヒロコ

菅谷 慱子  スガヤ ヒロコ

菅谷 博子

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Researcher Number 30235626
Other IDs
Affiliation (based on the past Project Information) *help 2003: 秋田大, 医学部, 助手
1991 – 2002: Akita University, Research Associate, 医学部, 助手
Review Section/Research Field
Principal Investigator
寄生虫学(含医用動物学) / Parasitology (including Sanitary zoology)
Except Principal Investigator
寄生虫学(含医用動物学) / 寄生虫学(含医用動物学)
Keywords
Principal Investigator
広東住血線虫 / Angiostrongylus cantonensis / 好酸球 / マウス / c / BALB / Rapid Translation System / major basic protein / T cell blot / IL-4 … More / 髄液好酸球 / マクロファージ / Acanthocheilonema viteae / cloning / worm killing / immunohistochemical staining / anti-MBP poyclonal antibody / eosinophil / His-tag / 塩基性蛋白質 / MBP-1 / エフェクター / クローニング / 殺虫作用 / 免疫組織化学染色 / 抗MBP抗体 / Nitric oxide / Interferon-γ / Morbidity / CD4^+T-cell / 好酸球増多 / 抗IL-4モノクローナル抗体 / magnetic microbeads / X線 / SAS-PAGE / T blot / 一酸化窒素 / interferon-γ / 病態 / CD4^+T細胞 / CD69抗原 / Flow cytometry / 低比重化 / IL-5トランスジェニックマウス / bcl-xL / bcl-2 / Caspase 3 / Annexin V / アポトーシス / IL-5 トランスジェニックマウス / NO / 皮下織 / 第3期感染幼虫 / 蛍光抗体法 / Flowcytometry / VCAM-1 / VLA-4 / 脳脊髄膜血管 / IgM / カラギ-ナン / 6 / C57BL / ミクロフィラリア / Millardia meltada … More
Except Principal Investigator
Angiostrongylus cantonensis / Mesocestoides corti / 好酸球 / 広東住血線虫 / BALB / IL-5 transgenic mice / RT-PCR / 髄液 / IL-5 transgenic mouse / マウス / サイトカイン / eosinophil / ELISA / B10 congenic mice / C.B-17 / c / 6 / C57BL / diffusion chamber / IgA / nu / c nu / N.brasiliensis / S.ratti / IL-4 / Th2 cytokine / Th1 cytokine / mouse / protection / cytokine / モノクローナル抗体 / Strongyloides ratti / 感染防御 / IL-3 / monoclonal antibody / cerebrospinal fluid / eosinophil chemotactic factor / affinity chromatography / 好酸球遊走因子 / genetic diagnosis / circulating antigen / slug / Brazil / Angiostrongylus costaricensis / Gelatin Particle Agglutination Test / Sarasinula linguaeformis / DNA診断 / 遺伝子診断 / 循環抗原 / ナメクジ / ブラジル / コスタリカ住血線虫 / Genetics / IFN-γ knockout mouse / chimeric mice / IL-10 / IFN-γ欠損マウス / B10 コンジェニックマウス / H-2 / X線照射 / 病態 / 好酸球増多 / T細胞キメラマウス / 骨髄キメラマウス / 抗IL-4モノクローナル抗体 / T cell blot / T細胞キメラ / 遺伝学 / B10 congenic mouse / INF-γ knockout mouse / キメラマウス / CD4^+T cell / C.B-17 scid / eosinophil-derived neurotoxin / eosinophil cationic protein / eosinophil peroxidase / major basic protein / CD8^+T細胞 / C.B.-17 scid / CD4^+T細胞 / diffusion shamber / C.B-17scid / IL-5 transgenicmouse / 広東住血線中 / flow cytometry / intraepitheliallymphocytes / parasite / フローサイトメトリー / 上皮間リンパ球 / 寄生虫 / IL-5 receptor alpha knockout mice / IFN-γ / IL-5 / Th2 / Th1 / IL‐5 receptor α knockout mouse / IL‐5 transgenic mouse / IL-5 receptor α knockout mouse / electron microscopy / mucosal mast cells / 腸管免疫 / 電子顕微鏡 / 粘膜肥満細胞 / blood-brain barrier / nude mice / eosinophils / 血液脳関門 / 脾細胞 / ヌードマウス / chemotactic assay / hypodense eosinophil / ラット / モルモット / レセプタ- / Western blotting / 間接蛍光抗体法 / chemotaxis assay / 低比重好酸球 / 単クロ-ン抗体 Less
  • Research Projects

    (15 results)
  • Co-Researchers

    (5 People)
  •  好酸球増多症マウスモデルを用いた原虫および線虫感染防御機構の免疫学的研究Principal Investigator

    • Principal Investigator
      島田 博子 (菅谷 博子)
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Akita University
  •  Immuno-molecular study on the role of eosinophil granule basic protein in experimental Angiostrongyliasis cantonensisPrincipal Investigator

    • Principal Investigator
      SHIMADA Hiroko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      AKITA UNIVERSITY
  •  Studies on the epidemiology, diagnosis and immunopathology of angiostrongyliasis costaricensis

    • Principal Investigator
      YOSHIMURA Kentaro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      AKITA UNIVERSITY
  •  Molecular immunological study on host morbidity of mice infected with Angiostrongylus cantonensis. -Analysis of the mechanisms of CD4^+T-cell-dependent body weight reduction and neurological symptoms-Principal Investigator

    • Principal Investigator
      SHIMADA Hiroko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      AKITA UNIVERSITY
  •  Molecular immunological study on the susceptibility and morbidity of T cell-chimeric mice to Angiostrongylus cantonensis

    • Principal Investigator
      YOSHIMURA Kentaro
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      AKITA UNIVERSITY
  •  広東住血線虫感染マウスにおける髄液好酸球の活性化ならびに細胞死機構の解明Principal Investigator

    • Principal Investigator
      島田 博子 (菅谷 博子)
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  •  Studies on helminthotoxicity and host morbidity by eosinophils from IL-5 transgenic mice in Angiostrongylus cantonensis infection

    • Principal Investigator
      YOSHIMURA Kentaro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      AKITA UNIVERSITY
  •  A.viteaeに対する先天的抵抗性機構に関する免疫学的研究Principal Investigator

    • Principal Investigator
      島田 博子
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  •  Studies on intraepithelial lymphocytes and cytokine production in the protection against nematode infection

    • Principal Investigator
      ABE Tatsuya
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  •  広東住血線虫感染における髄液好酸球集積と接着分子の役割Principal Investigator

    • Principal Investigator
      島田 博子 (菅谷 博子)
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  •  Th1/Th2 cytokine responses of Angiostrongyluscantonensis infected mice

    • Principal Investigator
      YOSHIMURA Kentaro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      AKITA UNIVERSITY
  •  Acanthocheilonemaミクロフィラリアの血中消失に関する免疫学的研究Principal Investigator

    • Principal Investigator
      島田 慱子 (菅谷 慱子)
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  •  Studies on effects of IL-3 in protection against intestinal parasites in vivo

    • Principal Investigator
      ABE Tatsuya
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  •  The mechanism of eosinophil accumulation in the cerebrospinal fluid of Angiostrongylus cantonensis infected hosts

    • Principal Investigator
      YOSHIMURA Kentaro
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  •  Immunological study on the mechanisms of local eosinophil infiltrations in helminthic infection.

    • Principal Investigator
      YOSHIMURA Kentaro
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Akita University
  • 1.  YOSHIMURA Kentaro (90053058)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  ISHIDA Kazuto (60006731)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  ABE Tatsuya (80128363)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  MATSUDA Shinji (70199800)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TANI Shigekazu (10006728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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