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HIRANO Takashi  平野 隆

ORCIDConnect your ORCID iD *help
… Alternative Names

平野 隆  ヒラノ タカシ

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Researcher Number 30238381
Affiliation (based on the past Project Information) *help 2007 – 2008: Tokyo Medical University, 医学部, 准教授
2005 – 2006: Tokyo Medical University, associate professor, 医学部, 助教授
2003 – 2004: 東京医科大学, 医学部, 講師
1998 – 1999: 東京医科大学, 医学部, 講師
1996: 東京医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Thoracic surgery / Thoracic surgery
Except Principal Investigator
Thoracic surgery / General surgery / Thoracic surgery
Keywords
Principal Investigator
2次元電気泳動法 / GST-π / reticulocalbin / TA02 / プロテオーム解析 / 肺癌 / lung cancer / mass spectrometry / two dimensional polyacrylamide gel electrophoresis / cancer associated proteins … More / proteotnic analysis / 癌個別治療 / プロテオーム / プロテオミクス / 乳癌 / 質量分析法 / 癌関連蛋白質 / Two-dimensional polyacrylamide gel electrophoresis / NapsinA / prognosis / antibody / lung cancer protein / 原発性肺癌 / reticulocarbin / 手術予後 / Napsin A / 予後 / 抗体 / 肺癌蛋白 / 術後補助化学療法 / 早期診断 / 効果予測因子 / チロシンキナーゼ阻害剤 / バイオマーカー / 呼吸器悪性腫瘍 / 呼吸器外科 / 臨床プロテオミクス / バイオマーカー探索 / 個別化治療 / 早期発見 / 中皮腫 … More
Except Principal Investigator
肺癌 / EGFR / methylation / 癌抑制遺伝子 / p16 / gefitinib / mutation / early diagnosis / tumor suppressor gene / NSCLC / ゲフィチニブ / 突然変異 / 早期診断 / メチル化 / 非小細胞肺癌 / screening / early cancer / cytometry / biomarker / lung cancer / 肺癌検診 / 癌遺伝子 / P16 / スクリーニング / 早期癌 / サイトメトリー / メチレーション / バイオマーカー / プロテオーム / マイクロアレイ / セルライン / 大細胞神経内分泌癌 / Mono-L-aspartyl chlorin e6 / 耐性株 / ダイオード・レーザー / 光線力学的治療法(Photodynamic Therapy ) Less
  • Research Projects

    (7 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (19 People)
  •  The establishment and analysis of new human lung cancer cell lines

    • Principal Investigator
      NOMURA Masaharu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tokyo Medical University
  •  Construction of the new diagnostic and therapeutic strategies based upon the biological characteristics of the respiratory malignancy (lung cancer and mesothelioma)Principal Investigator

    • Principal Investigator
      HIRANO Takashi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Tokyo Medical University
  •  The analysis of methylation, acetylation and mutation of the tumor suppressor gene in the lung cancer.

    • Principal Investigator
      MIYAJIMA Kuniharu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Tokyo Medical University
  •  Proteomic analysis of cancer associated proteins in the solid neoplasm -The analysis for individualized therapy for lung cancer-Principal Investigator

    • Principal Investigator
      HIRANO Takashi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Tokyo Medical University
  •  New methods of lung cancer screening using biomarker analysis in blood and sputum

    • Principal Investigator
      IKEDA Norihiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Tokyo Medical University
  •  Then analysis of lung cancer protein using two-dimensional polyacrylamide gel electrophoresis Application for adjuvant chemotherapyPrincipal Investigator

    • Principal Investigator
      HIRANO Takashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Tokyo Medical University
  •  肺扁平上皮癌におけるPhotodynamic Therapy (PDT)耐性株

    • Principal Investigator
      奥仲 哲弥
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Tokyo Medical University

All 2008 2007 2006 2005 2003

All Journal Article Presentation Book Patent

  • [Book] プロテオミクスによる呼吸器疾患解析, 別冊医学のあゆみ呼吸器疾患2007

    • Author(s)
      平野隆
    • Publisher
      医師薬出版
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Book] 肺がんにおけるプロテオーム解析-何をもたらすのか-, 呼吸器Common diseaseの診療肺がんのすべて2007

    • Author(s)
      平野隆
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Book] プロテオミクス解析に基づく原発性肺癌のバイオマーカー探索, MOOK 肺癌の臨床2005~2006(加藤治文, 西條長宏, 福岡正博, 小林紘一, 海老原善郎, 井内康輝, 早川和重)2006

    • Author(s)
      平野隆
    • Publisher
      篠原出版新社, 東京
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Book] 先端医療シリーズ26 呼吸器外科 プロテオミクスと肺癌外科2005

    • Author(s)
      加藤治文, 平野 隆
    • Total Pages
      6
    • Publisher
      先端医療技術研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Book] Mook 肺癌の臨床 Annual Review 2003,プロテオミクスの医療への応用 -その現状と発展性-2003

    • Author(s)
      平野 隆
    • Total Pages
      8
    • Publisher
      篠原出版新社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Book] 先端医療シリーズ20・癌 肺癌の最新医療 proteomicsによる診断2003

    • Author(s)
      平野 隆
    • Total Pages
      6
    • Publisher
      先端医療技術研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Proteomic analysis of stage I primary lung adenocarcinoma aimed at individualization of postoperative therapy2008

    • Author(s)
      Maeda J, Hirano T, Ogiwara A, et. al.
    • Journal Title

      British Journal of Cancer 98

      Pages: 596-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] 非小細胞肺癌における術後化学療法の効果予測を目指したバイオマーカー(Reticulocalbin)の評価2008

    • Author(s)
      片場寛明, 平野 隆, 他
    • Journal Title

      東京医科大学雑誌 66(2)

      Pages: 204-211

    • NAID

      120005335854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] Proteomic analysis of stage I primary lung adenocarcinoma aimed at individualization of postoperative therapy2008

    • Author(s)
      Junichi Maeda, Takashi Hirano, Atsushi Ogiwara, Shingo Akimoto, Takao Kawakami, Yousuke Fukui, Toshinori Oka, Yunbo Gong, Ran Guo, Hidehiro Inada, Kimitoshi, Nawa, Masakazu Kojika, Yasuhiro Suga, Tatsuo Ohira, Kiyoshi Mukai, Harubumi Kato
    • Journal Title

      British Journal of Cancer 98

      Pages: 596-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] Napsin A (TA02) is a useful alternative to thyroid transcription factor-1 (TTF-1) for the identification of pulmonary adenocarcinoma cells in pleural effusions2007

    • Author(s)
      Dejmek A, Naucler P, Smedjeback A, Kato H, Maeda M, Yashima K, Maeda J, Hirano T
    • Journal Title

      Diagn Cytopathol 35(8)

      Pages: 493-497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] 2次元電気泳動法により検出された非小細胞肺癌関連蛋白質の免疫組織化学染色による検証2007

    • Author(s)
      小鹿 雅和、平野 隆、松林 純, 他
    • Journal Title

      肺癌 47

      Pages: 861-869

    • NAID

      110006571323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] Personalized medicine and proteomics -Lessons from non-small cell lung cancer2007

    • Author(s)
      Gyorgy Marko-Varga, Atsushi Ogiwara, Toshihide Nishimura, Takeshi Kawamura, Kiyonaga Fujii, Takao Kawakami, Yutaka Kyono, Hsiao-kun Tu, Hisae Anyoji, Mitsuhiro Kanazawa, Shingo Akimoto, Takashi Hirano, Masahiro Tsuboi, Kazuto Nishio, Shuji Hada, Haiyi Jiang, Masahiro Fukuoka, Kouichiro Nakata, Yutaka Nishiwaki, Hideo Kunito, Ian S. Peers, Chris G. Harbron, Marie C. South, Tim Higenbottam, Fredrik Nyberg, Shoji Kudoh, Harubumi Kato
    • Journal Title

      Journal of Proteome Research 6(8)

      Pages: 2925-2935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] Personalized medicine and proteomicd:lesson from non-small cell lung cancer2007

    • Author(s)
      Marko-Varga G, Ogiwara A, Nishimura T, Hirano T, et. al.
    • Journal Title

      Journal Proteome Research 6

      Pages: 2925-2935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] Present status of clinical proteomic analysis for the early detection and determination of therapeutic strategy in lung cancer2006

    • Author(s)
      Hirano T, Kato H
    • Journal Title

      Ann Thorac Cardiovasc Surg 12

      Pages: 4-9

    • NAID

      10027077167

    • Data Source
      KAKENHI-PROJECT-18390382
  • [Journal Article] Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker2005

    • Author(s)
      Hirano T, Kato H, Maeda M, et al.
    • Journal Title

      International Journal of Cancer (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker2005

    • Author(s)
      Hirano T, Kato H, Maeda M, et al.
    • Journal Title

      International Journal of Cancer 117

      Pages: 460-468

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Clinical-scale high-throughput human proteomics analysis : lung adenocarcinoma2005

    • Author(s)
      Fuji K, Hirano T, Kato H, et al.
    • Journal Title

      Proteomics 5-4

      Pages: 1150-1159

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Clinical-scale high-throughput human proteomics analysis : lung adenocarcinoma2005

    • Author(s)
      Fujii K, Hirano T, Kato H, et al.
    • Journal Title

      Proteomics 5・4

      Pages: 1150-1159

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Clinical-scale high-throughput human plasma proteomics analysis : Lung adenocarcinoma2005

    • Author(s)
      Fuji K, Hirano T, Kato H, et al.
    • Journal Title

      Proteomics 5(4)

      Pages: 1150-1159

    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Identification of postoperative adjuvant chemotherapy responders in non-small cell lung cancer by novel biomarker2005

    • Author(s)
      Hirano T, Kato H, Maeda et al.
    • Journal Title

      International Journal of Cancer 117

      Pages: 460-468

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Usefulness of TA02 (napsin A) to distinguish primary lung adenocarcinoma from metastatic lung adenocarcinoma.2003

    • Author(s)
      Hirano T, Gong Y, Yoshida K, Kato Y, Yashima K, Maeda M, Nakagawa A, Fujioka K, Ohira T, Ikeda N, Ebihara Y, Auer G, Kato H.
    • Journal Title

      Lung Cancer 41(2)

      Pages: 155-162

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591494
  • [Journal Article] Usefulness of TA02 (napsin A) to distinguish primary lung adenocarcinoma from metastatic lung adenocarcinoma2003

    • Author(s)
      Hirano T, Gong Y, Yoshida K, et al.
    • Journal Title

      Lung Cancer 41

      Pages: 155-162

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390423
  • [Journal Article] Usefulness of TA02 (napsin A) to distinguish lung adenocarcinoma from metastatic lung adenocarcinoma.2003

    • Author(s)
      平野 隆
    • Journal Title

      Lung Cancer 41・2

      Pages: 155-162

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591494
  • [Patent] 手術後の予後を推定する方法及び診断キット2008

    • Inventor(s)
      福井陽介,荻原淳,秋元信吾,川上隆雄,平野隆,前田純一,加藤治文
    • Filing Date
      2008-10-17
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 蛋白質バイオマーカーの臨床使用に向けたプロテオームデータの統計解析手法の開発2008

    • Author(s)
      川上隆雄, 荻原淳, 和田計也, 高見幸子, 永坂恵子, 加藤治文, 平野隆
    • Organizer
      日本ヒトプロテオーム機構第6回大会
    • Place of Presentation
      大阪
    • Year and Date
      2008-07-30
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 組織プロテオームの液体クロマトグラフィー/タンデム質量分析による腫瘍診断マーカー蛋白質の探索とその検証2008

    • Author(s)
      川上隆雄, 荻原淳, 平野隆, 加藤治文
    • Organizer
      第33回日本医用マススペクトル学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-26
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] Discovery and validatoion of the protein biomarkers for tumor diagnosis : Differential analyses of the liquid chromatography/tandem mass spectrometry profiles from the tissue proteomes2008

    • Author(s)
      Takao Kawakami, Atsushi Ogiwara, Kazuya Wada, Takashi Hirano, Harubumi Kato, Norihiko Ikeda
    • Organizer
      17th Meeting of Methods in Protein Structure Analysis
    • Place of Presentation
      Sapporo
    • Year and Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 臨床応用に向けた肺癌のプロテオーム解析2007

    • Author(s)
      平野 隆
    • Organizer
      第33回日本肺癌学会北海道支部会 特別講演
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-06
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] Discovery of metastasis factors from in-depth proteome analysis of formalin-fixed lung carcinoma tissues2007

    • Author(s)
      Hirano T, Ohira T, Nomura M, Nishimura T, Nishiyama R, Fujii K, Bando Y, Mukai K, Kato H
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 臨床応用に向けた肺癌のプロテオーム解析2007

    • Author(s)
      平野隆, 前田純一, 片場寛明, 小鹿雅和, 垣花昌俊, 本多英俊, 中嶋英治, 大平達夫, 坪井正博, 加藤治文
    • Organizer
      第48回日本肺癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-11-08
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] Future aspects of clinical cytology in lung neoplasms:Lung cancer diagnosis based on proteomic analysis and digital slide scanning2007

    • Author(s)
      Hirano T, Furioka K, Maeda J, et. al.
    • Organizer
      16th International Congress of Cytology
    • Place of Presentation
      Vancouver,Canada
    • Year and Date
      2007-05-15
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 臨床応用に向けた肺癌のプロテオーム解析2007

    • Author(s)
      平野隆
    • Organizer
      第33回日本肺癌学会北海道支部会(特別講演)
    • Place of Presentation
      札幌
    • Year and Date
      2007-10-06
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 原発性肺癌の術後治療の個別化に向けたプロテオーム解析の試み2007

    • Author(s)
      平野隆, 前田純一, 吉田浩一, 小鹿雅和, 坂田義詞, 佐治久, 垣花昌俊, 藤岡薫, 大平達夫, 坪井正博, 加藤治文
    • Organizer
      第107回日本外科学会定期学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-13
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] I 期肺腺癌切除症例のプロテオーム解析-UFTによる術後補助化学療法との関係-2006

    • Author(s)
      前田純一, 平野隆, 秋元信吾, 稲田秀洋, 大平達夫, 坪井正博, 荻原淳, 川上隆雄, 西村俊秀, 加藤治文
    • Organizer
      日本ヒトプロテオーム機構第4回大会, 第2回日本臨床プロテオーム研究会, 合同年会
    • Place of Presentation
      新宿
    • Year and Date
      2006-07-18
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] Possibility of the prediction of an adverse effect (interstitial lung disease) by gefitinib (an interim report)2006

    • Author(s)
      Hirano T, Ogiwara A, Maeda J, Yoshida K, Fujioka K, Nomura M, Kakihana N, Kajiwara N, Ohira T, Tsuboi M, Kato H
    • Organizer
      The joint meeting of 3^<rd> ISC International Conference on Cancer Therapeutics and the 11^<th> International Symposium on Cancer Chemotherapy
    • Place of Presentation
      Tokyo
    • Year and Date
      2006-12-06
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] チロシンキナーゼ阻害剤による薬剤生間質性肺炎のバイオマーカー探索2006

    • Author(s)
      平野隆, 大平達夫, 荻原淳, 秋元信吾, 羽田修二, 坪井正博, 加藤治文
    • Organizer
      第12回薬剤疫学学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2006-11-14
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 臨床応用を目指した肺癌のプロテオーム解析2006

    • Author(s)
      平野隆, 大平達夫, 前田雅弘, 荻原淳, 秋元信吾, 西村俊秀, 加藤治文
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-29
    • Data Source
      KAKENHI-PROJECT-18390382
  • [Presentation] 肺癌個別治療をめざしたプロテオーム解析の現状2006

    • Author(s)
      平野隆, 前田純一, 片場寛明, 野村将晴, 垣花昌俊, 梶原直央, 大平達夫, 坪井正博, 西村俊秀, 加藤治文
    • Organizer
      第44回日本癌治療学会総会
    • Place of Presentation
      東京
    • Year and Date
      2006-10-19
    • Data Source
      KAKENHI-PROJECT-18390382
  • 1.  KATO Harubumi (20074768)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 23 results
  • 2.  OHIRA Tatsuo (40317847)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 9 results
  • 3.  NISHIMURA Toshihide (40366092)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 4.  IKEDA Norihiko (70246205)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 5.  HONDA Hidetoshi (60349503)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  SAJI Hisashi (60420965)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  KAWAKAMI Takao (40366117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  NOMURA Masaharu (40424494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KONAKA Chimori (70147180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KAWATE Norihiko (70204740)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  YAMADA Kimito (10349475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TSUTSUI Hidemiru (50328233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HONDA Hidetoshi (70246297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MIYAJIMA Kuniharu (80372952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SUGA Yasuhiro (40408258)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  奥仲 哲弥 (80233469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  古川 欣也 (20246292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  酒井 治正 (30235121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  前田 雅弘
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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