YOKOMURO Shigeki 横室茂樹

Researcher Number	30267223
Affiliation (based on the past Project Information) *help	2018: 日本医科大学, 医学部, 准教授 2017: 日本医科大学, 医学部, 病院教授 2016: 日本医科大学, 医学部, 准教授 2007: 日本医科大学, 医学部, 准教授 2004 – 2007: 日本医科大学, 医学部, 講師 2000 – 2004: 日本医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Emergency medicine / Digestive surgery / Digestive surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator IL-6 / TGFβ_1 / HGF / RNAi / TGFβ1 / 胆管癌 / 感染症 / C-reactive protein (CRP) / 敗血症 / TGF-β1 … More / Cholangiocarcinoma / 胆管上皮癌 / TGFB1 / TGFβ / cholangiocarcinoma / サイトカイン / 胆管上皮細胞癌 … More Except Principal Investigator Sequencing / Bioinformatics / Hepatitis B virus / MicroRNA / Hepatocellular carcinoma / マイクロRNA / バイオテクノロジー / 遺伝子 / TGF beta receptor II / TGF beta / gene therapy / liver injury / RNA interference / TGF-β recepter II / TGF-β receptor II / TGF-β1 / 遺伝子治療 / 肝障害 / RNA干渉 Less

The effect for C-reactive protein (CRP) for sever sepsisPrincipal Investigator
- Principal Investigator
  
  YOKOMURO Shigeki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Nippon Medical School
Sequencing based quantitative and qualitative analyses of the microRNA transcriptome in hepatitis B related hepatocellular carcinoma.
- Principal Investigator
  
  TAJIRI Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Gene therapy of chronic liver injury with RNAi vector targeting TGF-beta receptor
- Principal Investigator
  
  TAJIRI Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Application of IL-6 HGF, TGF beta 1 for a bile duct cancer treatment.Principal Investigator
- Principal Investigator
  
  YOKOMURO Shigeki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
The role of IL-6, HGF and TGFβ_1 in biliary epithelial cells carcinogenesisPrincipal Investigator
- Principal Investigator
  
  YOKOMURO Shigeki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon medical school

All 2007 2005 2004 Other

All Journal Article Patent

[Journal Article] Therapeutic use of short hairpin RNA in acute liver failure.2007
- Author(s)
  Mizuguchi Y, Yokomuro S, Mishima T, Arima Y, Shimizu T, Kawahigashi Y, Takizawa T, Tajiri T.
- Journal Title
  
  Nippon Med Sch. 74(1).
  
  Pages: 74-6
- NAID
  130004146890
- Data Source
  KAKENHI-PROJECT-18390372
[Journal Article] Short Hairpin RNA Modulates Transforming Groowth Factor Signaling in Life-Threatening Liver Failure in Mice Short Hairpin RNA Modulates Transforming Growth Factor Signaling in Life-Threatening Liver Failure in Mice2005
- Author(s)
  YOSHIAKI MIZUGUCHI, SHIGEKI YOKOMURO, et al.
- Journal Title
  
  GASTROENTEROLOGY 129
  
  Pages: 1654-62
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591450
[Journal Article] Short hairpin RNA modulates transforming growth factor beta signaling in life-threatening liverfailure in mice.2005
- Author(s)
  Mizuguchi Y, Yokomuro S, Mishima T, Arima Y, Shimizu T, Kawahigashi Y, Kanda T, Yoshida H, Takizawa T, Tajiri T.
- Journal Title
  
  Gastroenterology 129
  
  Pages: 1654-1662
- Data Source
  KAKENHI-PROJECT-15591450
[Journal Article] Short hairpin RNA modulates transforming growth factor beta signaling in life-threatening liverfailure in mice.2005
- Author(s)
  Mizuguchi Y, Yokomuro S, Mishima T, Arima Y, Shimizu T, Kawahigashi Y, Kanda T, Yoshida H, Takizawa T, Tajiri T.
- Journal Title
  
  Gastroenterology 129
  
  Pages: 1654-1662
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591364
[Journal Article] Short Hairpin RNA Modulates Transforming Growth Factor Signaling in Life-Threatening Liver Failure in Mice Short Hairpin RNA Modulates Transforming Growth Factor Signaling in Life-Threatening Liver Failure in Mice2005
- Author(s)
  YOSHIAKI MIZUGUCHI, SHIGEKI YOKOMURO, et al.
- Journal Title
  
  GASTROENTEROLOGY 129
  
  Pages: 1654-1662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591450
[Journal Article] マウス正常肝内胆管上皮細胞培養の確立"Transforming Growth Factor-β1による胆管上皮細胞増殖抑制"2004
- Author(s)
  横室茂樹
- Journal Title
  
  胆道 18
  
  Pages: 193-197
- NAID
  10031122747
- Data Source
  KAKENHI-PROJECT-15591450
[Patent] TGFβ1レセプターII型に対するRNAiとして作用するRNA配列2004
- Inventor(s)
  横室茂樹, 水口義昭
- Filing Date
  2004-03-10
- Data Source
  KAKENHI-PROJECT-15591450
[Patent] Sequences of RNA functioning as RNA interference targeting human and mouse transforming growth factor betal receptor 22004
- Inventor(s)
  水口義昭, 三嶋拓也, 瀧澤敏広, 田尻孝, 横室茂樹
- Industrial Property Rights Holder
  水口義昭, 三嶋拓也, 瀧澤敏広, 田尻孝, 横室茂樹
- Filing Date
  2004
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591364
[Patent] Sequences of RNA functioning as RNA interference targeting human and mouse transforming growth factor beta1 receptor 22004
- Inventor(s)
  水口義昭, 三嶋拓也, 瀧澤敏広, 田尻孝, 横室茂樹
- Industrial Property Rights Holder
  水口義昭, 三嶋拓也, 瀧澤敏広, 田尻孝, 横室茂樹
- Filing Date
  2004
- Data Source
  KAKENHI-PROJECT-16591364
[Patent] TGFβ1レセプターII型に対するRNAiとして作用するRNA配列
- Inventor(s)
  横室茂樹, 水口義昭
- Industrial Property Rights Holder
  P04-0092
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591450

1. TAJIRI Takashi (20163462)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. ARIMA Yasuo (30168025)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. YOSHIDA Hiroshi (60246999)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MIZUGUCHI Yoshiaki (70409217)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. AKIMARU Koho (40142541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 松田明久 (00366741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 宮下正夫 (70229847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山田真吏奈 (70508621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 木下学 (70531391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SEKIGUCHI Kumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOKOMURO Shigeki 横室 茂樹

Research Projects

Research Products

Co-Researchers

The effect for C-reactive protein (CRP) for sever sepsisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sequencing based quantitative and qualitative analyses of the microRNA transcriptome in hepatitis B related hepatocellular carcinoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene therapy of chronic liver injury with RNAi vector targeting TGF-beta receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of IL-6 HGF, TGF beta 1 for a bile duct cancer treatment.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of IL-6, HGF and TGFβ_1 in biliary epithelial cells carcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Therapeutic use of short hairpin RNA in acute liver failure.2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Short Hairpin RNA Modulates Transforming Groowth Factor Signaling in Life-Threatening Liver Failure in Mice Short Hairpin RNA Modulates Transforming Growth Factor Signaling in Life-Threatening Liver Failure in Mice2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Short hairpin RNA modulates transforming growth factor beta signaling in life-threatening liverfailure in mice.2005

Author(s)

Journal Title

Data Source

[Journal Article] Short hairpin RNA modulates transforming growth factor beta signaling in life-threatening liverfailure in mice.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Short Hairpin RNA Modulates Transforming Growth Factor Signaling in Life-Threatening Liver Failure in Mice Short Hairpin RNA Modulates Transforming Growth Factor Signaling in Life-Threatening Liver Failure in Mice2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] マウス正常肝内胆管上皮細胞培養の確立"Transforming Growth Factor-β1による胆管上皮細胞増殖抑制"2004

Author(s)

Journal Title

NAID

Data Source

[Patent] TGFβ1レセプターII型に対するRNAiとして作用するRNA配列2004

Inventor(s)

Filing Date

Data Source

[Patent] Sequences of RNA functioning as RNA interference targeting human and mouse transforming growth factor betal receptor 22004

Inventor(s)

Industrial Property Rights Holder

Filing Date

Description

Data Source

[Patent] Sequences of RNA functioning as RNA interference targeting human and mouse transforming growth factor beta1 receptor 22004

Inventor(s)

Industrial Property Rights Holder

Filing Date

Data Source

[Patent] TGFβ1レセプターII型に対するRNAiとして作用するRNA配列

Inventor(s)

YOKOMURO Shigeki 横室茂樹