YAMAGUCHI Yukitoshi 山口之利

Researcher Number	30277339
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1997 – 2003: 東邦大学, 医学部, 講師 1997: Toho Univ., 2nd Dept.of pediatrics, Assistant professor, 医学部・第2小児科学教室, 講師 1996 – 1997: 東邦大学, 医学部, 助手 1996: 東邦大学, 医学部・第二小児科学教室, 助手 1996: Toho Univ., 2nd Dept.of Pediatrics, Staff, 第二小児科学教室, 助手 1995: 東邦大学, 医学部・第2小児科学教室, 助手
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator Wilson病 / 銅輸送ATPase / ATP-7B / Menkes病 / Western Blotting / HepG2細胞 / ポリクローナル抗体 Except Principal Investigator ATP7B / Wilson disease / 遺伝子解析 … More / Menkes病 / Wilson病 / ATP7A / 銅輸送P-type ATPase / Menkes disease / inborn error of copper metabolism / P-type ATPase / DRB1^1302 / HLA DR / genotype-phenotype correlation / DQB1^0604 / 小児期発症重症筋無力症 / 潜在性全身型 / 重症筋無力症 / 銅特異的ATPase活性 / 遺伝子診断 / gene analysis / 先天性銅代謝異常症 / 遺伝性銅代謝異常症 / DOB1^0604 / DOA1^0102 / latent general type / DO allele / seronegative autoimrnmue / ant-acetylcholine receptor autoantibody / childhood-onset myasthenia gravis / TCR V_βクローンレパートリー / T細胞レセプター / DQアリルタイプ / セロネガティブ自己免疫疾患 / 抗アセチルコリンレセプター抗体 / TCRVα鎖β鎖レパートリー / AChR抗原特異的T細胞 / AChR / DQA1^0302 / TCRVαVβレパートリー / DQタイプ / HLA-DR / PQB1^0604 / DQA1^0102 / 自己抗体潜在性全身型 / DQアリル / セロネガティブ自己免疫 / 抗アセチルコリンレセプター / copper induced ATPase activity / molecular analysis / 銅輸送P-type ATRase / ATPase活性 / 血清セルロプラスミン値 / 遺伝子変異と病型 / 遣伝子解析 / TH1-like phenotype / AChR sensitized CD4+ T cell / HLA-DQB chain / seronegative autoimmune diseases / AChR antibody / childhood-onset MG / 産生リンホカインレパトリー / CD4^+AChR応答細胞 / 抗AChR抗体 / AChR応答T細胞 / TH0タイプ / TH1 / TCRVβレパトリー / TCRVα / CDR3領域のアミノ酸配列 / HLA-ClassIIアリルタイプ / 重症筋無力症潜在性全身型 / TH1細胞 / TCRVβクローン / TCRVαクローン / DQB鎖アミノ酸多型 / HLA-DQB1^0604 / 抗アセチルコリンレセブター抗体 / presymptomatic diagnosis / tetrathiomolybdate (TTM) / molecular diagnosis / Tetrathiomolybdate (TTM) / 遺伝性銅代謝異常 / テトラチオモリブデン(TTM) / 発症前診断 / テトラチオモリブテン(TTM) / intracellular localization / copper transporting P-type A Tpase / Inborn error of copper metabolism / 細胞内局在 / phenotype / genotype / genotypeとphenotype / Phenotype / Genotype Less

Research Projects
(9 results)
Co-Researchers
(11 People)

ANALYSIS OF THE PATHOGENESIS OF THE SERONEGATIVE AUTOIMUNE DISEASE
- Principal Investigator
  
  SHINOMIYA Noriaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  TOHO UNIVERSITY
Wilson病銅輸送ATPaseの組織内局在の検討Principal Investigator
- Principal Investigator
  
  山口之利
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University
Immunogenetic analysis of the pathogenesis of the seronegative autoimmune disease
- Principal Investigator
  
  SHINOMIYA Noriaki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University
Strategy of ATP7B gene analysis for Japanese patients with Wilson disease, using ARMS method. ..................................
- Principal Investigator
  
  SHIMIZU Norikazu
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Toho Unversity School of Medicine
Wilson病・Menkes病銅輸送ATPaseの組織・細胞内局在の検討Principal Investigator
- Principal Investigator
  
  山口之利
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University
The etiology of inborn error of copper metabolism, new method of treatment, and function of P-type copper transporting ATPase
- Principal Investigator
  
  AOKI Tugutoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University School of Medicine
Wilson病タンパクにおけるポリクローナル抗体を用いた肝細織細胞内局在の検討Principal Investigator
- Principal Investigator
  
  山口之利
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University
The structural and functional analysis of copper transporting P-type ATPase in inborn error of copper metabolism
- Principal Investigator
  
  SHIMIZU Norikazu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University School of Medicine
Correlation between genotype and phenotype of inborn error of copper metabolism
- Principal Investigator
  
  AOKI Tsugutoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University

1. SHIMIZU Norikazu (60256740)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. HEMMI Hiromich (90165514)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. AOKI Tsugutoshi (50057585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. FUJIOKA Yoshimi (30256739)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHINOMIYA Noriaki (10104225)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NIHEI Kouichi (20218241)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. INOUE Akira (10151599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAZAMA Hiromi (90224386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UCHIYAMA Tishimitu (50057709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHIMATAKE Hiroyuki (40010110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UNO Taku (30318240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAGUCHI Yukitoshi 山口 之利

Research Projects

Co-Researchers

ANALYSIS OF THE PATHOGENESIS OF THE SERONEGATIVE AUTOIMUNE DISEASE

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Wilson病銅輸送ATPaseの組織内局在の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunogenetic analysis of the pathogenesis of the seronegative autoimmune disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Strategy of ATP7B gene analysis for Japanese patients with Wilson disease, using ARMS method. ..................................

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Wilson病・Menkes病銅輸送ATPaseの組織・細胞内局在の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The etiology of inborn error of copper metabolism, new method of treatment, and function of P-type copper transporting ATPase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Wilson病タンパクにおけるポリクローナル抗体を用いた肝細織細胞内局在の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The structural and functional analysis of copper transporting P-type ATPase in inborn error of copper metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Correlation between genotype and phenotype of inborn error of copper metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

YAMAGUCHI Yukitoshi 山口之利