Saito Kazuyoshi 斉藤和義

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SAITO Kazuyoshi 斉藤和義

齋藤和義サイトウカズヨシ

斉藤和義サイトウカズヨシ

斎藤和義サイトウカズヨシ

齊藤和義サイトウカズヨシ

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Researcher Number	30279327
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 非常勤医師
Affiliation (based on the past Project Information) *help	2017: 産業医科大学, 医学部, 非常勤医師 2015 – 2016: 産業医科大学, 医学部, 准教授 2007 – 2013: University of Occupational and Environmental Health, Japan, School of Medicine, associate professor 2005 – 2006: University of Occupational and Environmental Health, School of Medicine, associate professor, 医学部, 助教授 2001 – 2004: 産業医科大学, 医学部, 講師 1996 – 1998: 産業医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / 内科学一般 / Collagenous pathology/Allergology Except Principal Investigator 膠原病・アレルギー・感染症内科学 / Medical sociology / 内科学一般 / Applied pharmacology
Keywords	Principal Investigator 転写因子 / 膠原病 / 細胞接着 / 慢性関節リウマチ / FOXP-3 / CD25 / CD4 / Wnt10 / リモデリング抑制 / 遺伝子発現調節 … More / 滑膜細胞 / ICAM-1 / IL-1β / transcriptional regulation / transcriptional factor / inflammatory cytokine / IL1 beta / 炎症性サイトカイン / autoimmune / regulatory T lymphocyte / FOX-3 / 自己免疫 / 制御性Tリンパ球 / angiostatin / monoclonal antibody / gene therapy / rheumatoid arthritis / 血管新生抑制因子 / 遺伝子導入 / 自己抗体 / 抗転写因子抗体 / 膠原病学 / MAPK / VCAM-1 / サイトカイン … More Except Principal Investigator TNF阻害薬 / 関節リウマチ / リンパ球 / メトトレキサート / 構造的寛解 / 休薬 / 職業的寛解 / 機能的寛解 / 臨床的寛解 / 寛解 / メソトレキサート / Lymphocytes / P-glycoprotein / drug resistance / 遺伝子発現調節 / P-糖蛋白質 / 多剤耐性遺伝子 / organ-tropism / homing molecules / adhesion molecules / co-stimulatory molecules / integrin / endothelial cells / T cells / systemic lupus erythematosus / サイトカイン / 全身エリテマトーデス / 共刺激分子 / 臓器特異的浸潤 / 帰巣分子 / 細胞表面抗原 / インテグリン / 血管内皮細胞 / T細胞 / 全身性エリテマトーデス / 悪性腫瘍 / 薬剤適正使用 / 重篤有害事象 / 患者登録システム / 安全性 / 薬剤疫学 / 生物学的製剤 / ケースコントロール研究 / ミューモシスチス肺炎 Less

Novel strategies for treatment of rheumatic diseases by Wnt signal blockadesPrincipal Investigator
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Occupational and Environmental Health, Japan
Establishment of the treatment algorithm of the rheumatoid arthritis aimed at clinical, functional and occupational remission.
- Principal Investigator
  
  NAWATA Masao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical sociology
- Research Institution
  University of Occupational and Environmental Health, Japan
Involvement of Epithelial and endothelial to mesenchymal transition in tissue remolding of rheumatic diseasesPrincipal Investigator
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
A epidemiological study of long-term safety of biological disease-modifying antirheumatic drugs for patients with rheumatoid arthritis and risk factors for adverse drug reactions.
- Principal Investigator
  
  HARIGAI Masayoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tokyo Medical and Dental University
A New treatment strategy using analysis of anti-transcriptional factors antibody in connective tissue diseases.Principal Investigator
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
関節リウマチに対するTNF阻害療法中のニューモシスティス肺炎予防指針の確立
- Principal Investigator
  
  KOIKE Ryuji
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tokyo Medical and Dental University
Therapeutic strategy for inflammatory diseases by a novel negative regulatory transcriptional factor of inflammatory cytokinesPrincipal Investigator
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Treatment strategy for connective tissue diseases using evaluation of P-glycoprotein on lymphocytes
- Principal Investigator
  
  NAKATUSKA Kiesuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Analysis of Regulation of FOXP3 expression and induction of regulatory T cells for therapeutic application to autoimmune diseases.Principal Investigator
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health
Identification of organ-specific cell surface molecules on T cells and endothelial cells in patients with systemic lupus erythematosus
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health, Japan
Treatment for rheumatoid arthritis with immunogene therapy by angiostatinPrincipal Investigator
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health
慢性関節リウマチ滑膜細胞の接着分子を介した細胞内シグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  齋藤和義 (齊藤和義)
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health, Japan
慢性関節リウマチ滑膜における接着分子を介した炎症性サイトカイン産生増強機構の解析Principal Investigator
- Principal Investigator
  
  齋藤和義
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2011 2010 2009 2007 2005 2004

All Journal Article Presentation

[Journal Article] Phenotypic Changes of Lymphocytes in Patients with Systemic Lupus Erythematosus who are in the long-term remission After B Cell Depletion Therapy with Rituximab2011
- Author(s)
  Iwata S, Saito K, Tokunaga M, Yamaoka K, Nawata M, Yukawa S, Hanami K, Fukuyo S, Kubo S, Miyagawa I, Tanaka Y
- Journal Title
  
  Journal of Rheumatology 38(4)
  
  Pages: 633-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Phenotypic Changes of Lymphocytes in Patients with Systemic Lupus Erythematosus who are in the long-term remission After B Cell Depletion Therapy with Rituximab2011
- Author(s)
  Iwata S, Saito K, et al.
- Journal Title
  
  Journal of Rheumatology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Efficacy of combination therapy of anti-TNF-a antibody infliximab and methotrexate in refractory entero-Behcet's disease2011
- Author(s)
  Iwata S, Saito K, et al.
- Journal Title
  
  Mod Rheumatol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behcet's disease.2011
- Author(s)
  Iwata S, Saito K, Yamaoka K, Tsujimura S, Nawata M, Hanami K, Tanaka Y
- Journal Title
  
  Mod Rheumatol. 21(2)
  
  Pages: 184-91
- NAID
  10029361883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Etanercept overcomes P-glycoprotein-induced drug resistance in lymphocytes of patients with intractable rheumatoid arthritis.2010
- Author(s)
  Tsujimura S, Saito K, Nakayamada S, Tanaka Y
- Journal Title
  
  Modern Rheumatology 20(2)
  
  Pages: 139-146
- NAID
  10027168842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Tacrolimus, a calcineurin inhibitor, overcomes treatment unresponsiveness me diated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis2010
- Author(s)
  Suzuki K, Saito K, et al.
- Journal Title
  
  J Rheumatol. 37(3)
  
  Pages: 512-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Etanercept overcomes P-glycoprotein-induced drug resistance in lymphocytes of patients with intractable rheumatoid arthritis2010
- Author(s)
  Tsujimura S, Saito K,, et al.
- Journal Title
  
  Modern Rheumatology (in press)
- NAID
  10027168842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Tacrolimus, a calcineurin inhibitor, overcomes treatment unresponsiveness mediated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis.2010
- Author(s)
  Suzuki K, Saito K, Tsujimura S, Nakayamada S, Yamaoka K, Sawamukai N, Iwata S, Nawata M, Nakano K, Tanaka Y
- Journal Title
  
  J Rheumatol. 37(3)
  
  Pages: 512-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Effects of anti-TNF-alpha antibody infliximab in refractory entero-Behcet's disease.2009
- Author(s)
  Iwata S, Saito K, Yamaoka K, Tsujimura S, Nawata M, Suzuki K, Tanaka Y
- Journal Title
  
  Rheumatology 48(8)
  
  Pages: 1012-1013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Japan College of Rheumatology 2009 guidelines for the use of to cilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis.2009
- Author(s)
  Koike R, 針谷正祥, Atsumi T, Amano K, Kawai S, Saito K, Saito T, Yamamura M, Matsubara T, Miyasaka N.
- Journal Title
  
  Modern Rheumatology 19
  
  Pages: 351-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390158
[Journal Article] Effects of anti-TNF-alpha antibody infliximab in refractory entero-Behcet's disease.2009
- Author(s)
  Iwata S, Saito K, et al.
- Journal Title
  
  Rheumatology 48(8)
  
  Pages: 1012-1013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Extremely high titer of anti-human chimeric antibody following re-treatment with rituximab in a patient with active systemic lupus erythematosus.2005
- Author(s)
  Saito, K.et al.
- Journal Title
  
  Rheumatology 44(11)
  
  Pages: 1462-1464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591002
[Journal Article] Extremely high titer of anti-human chimeric antibody following re-treatment with rituximab in a patient with active systemic lupuserythematosus.2005
- Author(s)
  Saito, K.
- Journal Title
  
  Rheumatology 44巻11号
  
  Pages: 1462-1464
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591002
[Journal Article] Detection of Pneumocystis carinii by DNA amplification in patients with connective tissue diseases : re-evaluation of clinical features of p.carinii pneumonia in rheumatic diseases2004
- Author(s)
  Saito, K.
- Journal Title
  
  Rheumatology 43巻4号
  
  Pages: 479-485
- Data Source
  KAKENHI-PROJECT-16591002
[Presentation] Humanized anti human Interlukin-6 receptor monoclonal antibody tocilizumab (TCZ) increases high molecular weight adiponectin (HMW-AN) in the patients with rheumatoid arthritis (RA) : result from The ESCORT study2010
- Author(s)
  Saito K, Hanami k, Nawata M, Yunoue N, Tanaka Y
- Organizer
  The 11th Annual European Congress of Rheumatology (EULAR)
- Place of Presentation
  Roma(Fiera Rome)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20591179
[Presentation] Humanized anti-human Intedukin-6 receptor monoclonal antibody tocilizumab(TCZ)increases high molecules weight adiponectin(HMW-AN)in the patients with rheumatoid arthritis(RA): result from The ESCORT study2010
- Author(s)
  Saito K
- Organizer
  The 11th Annual European Congress of Rheu matology(EULAR)
- Place of Presentation
  Roma(Fiera Rome)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20591179
[Presentation] 難治性全身性エリテマトーデスに対するCD20抗体の効果2007
- Author(s)
  齋藤和義
- Organizer
  第51回日本内科学会総会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591128

1. TANAKA Yoshiya (30248562)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
2. KOIKE Ryuji (50250220)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. HARIGAI Masayoshi (20238207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MIYASAKA Nobuyuki (30157622)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. ATSUMI Tatsuya (20301905)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. KOHNO Kimitoshi (00153479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NANKI Toshihiro (00282749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKENO Mitsuhiro (50236494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAMEDA Hideto (00265795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJII Takao (70255462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TSUTANI Kiichiro (80142040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAWADA Tetsuji (50235470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAMURA Naoto (20227284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TOHMA Shigeto (50207528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAWAKAMI Atsushi (90325639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HAYASHI Taichi (00466674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAKAMURA Takahiro (60415255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OKADA Yosuke (80333243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TSUKADA Junichi (20227367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YAMAOKA Kunihiro (20425317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAKATUSKA Kiesuki (00291633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NAWATA Masao (20389430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 関口直哉 (70327063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 伊藤聡 (00334681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 和泉弘人 (50289576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Saito Kazuyoshi 斉藤 和義

SAITO Kazuyoshi 斉藤 和義

齋藤 和義 サイトウ カズヨシ

斉藤 和義 サイトウ カズヨシ

斎藤 和義 サイトウ カズヨシ

齊藤 和義 サイトウ カズヨシ

Research Projects

Research Products

Co-Researchers

Novel strategies for treatment of rheumatic diseases by Wnt signal blockadesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of the treatment algorithm of the rheumatoid arthritis aimed at clinical, functional and occupational remission.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of Epithelial and endothelial to mesenchymal transition in tissue remolding of rheumatic diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A epidemiological study of long-term safety of biological disease-modifying antirheumatic drugs for patients with rheumatoid arthritis and risk factors for adverse drug reactions.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A New treatment strategy using analysis of anti-transcriptional factors antibody in connective tissue diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

関節リウマチに対するTNF阻害療法中のニューモシスティス肺炎予防指針の確立

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic strategy for inflammatory diseases by a novel negative regulatory transcriptional factor of inflammatory cytokinesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Treatment strategy for connective tissue diseases using evaluation of P-glycoprotein on lymphocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Regulation of FOXP3 expression and induction of regulatory T cells for therapeutic application to autoimmune diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of organ-specific cell surface molecules on T cells and endothelial cells in patients with systemic lupus erythematosus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Treatment for rheumatoid arthritis with immunogene therapy by angiostatinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

慢性関節リウマチ滑膜細胞の接着分子を介した細胞内シグナル伝達機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Saito Kazuyoshi 斉藤和義

SAITO Kazuyoshi 斉藤和義

齋藤和義サイトウカズヨシ

斉藤和義サイトウカズヨシ

斎藤和義サイトウカズヨシ

齊藤和義サイトウカズヨシ