Kurose Kouichi 黒瀬光一

… Alternative Names

KUROSE Koichi 黒瀬光一

KUROSE Kouichi 黒瀬光一

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Researcher Number	30280754
Other IDs
Affiliation (Current)	2025: 東京海洋大学, 学術研究院, 教授 2025: 国立医薬品食品衛生研究所, 医薬安全科学部, 客員研究員
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京海洋大学, 学術研究院, 教授 2015: 東京海洋大学, その他部局等, 教授 2013 – 2014: 東京海洋大学, 海洋科学技術研究科, 教授 2013: 国立医薬品食品衛生研究所, 医薬安全科学部, 第三室長 2010 – 2012: 国立医薬品食品衛生研究所, 医薬安全科学部, 室長 1999 – 2001: 国立公衆衛生院, 衛生薬学部, 主任研究官
Review Section/Research Field	Principal Investigator Basic Section 08030:Family and consumer sciences, and culture and living-related / Eating habits / Drug development chemistry / 環境影響評価(含放射線生物学) Except Principal Investigator Aquatic life science / Biological pharmacy / Applied pharmacology / Medical pharmacy
Keywords	Principal Investigator 代替法試験 / THP-1 / エンドトキシン / アレルゲン / 樹状細胞 / 食物アレルギー / アレルギー / 免疫原性試験 / 食の安全安心 / LPS … More / アレルゲン性試験 / 感作性 / 薬物アレルギー / インビトロ試験法 / ゼノパス / 遺伝子発現プロファイル / エストラジオール / 内分泌撹乱物質 / 環境ホルモン / エストロゲン / レクチン / DNAマイクロアレイ / ビスフェノールA / アフリカツメガエル / 内分泌撹乱化学物質 … More Except Principal Investigator CYP2A8 / 抗がん剤 / 水産食品加工・貯蔵 / かまぼこ / オオグソクムシ / GENE EXPRESSION / DIOXIN / 核内転写因子 / 遺伝子転写活性 / ダイオキシン受容体 / XRE / AHR / 核内因子 / One hybrid screening / マウス肝臓 / 転写因子 / シトクロムP450 / 芳香族炭化水素化合物 / ファーマコゲノミクス / 医薬品副作用 / 副作用 / 抗体医薬品 / 遺伝子 / 薬理学 / 臨床 / ゲノム / ハプロタイプ / 遺伝子多型 / 薬剤反応性 / α-1-酸性糖蛋白 / オーダーメード医療 Less

カブトガニを救う新規エンドトキシン試験法の開発Principal Investigator
- Principal Investigator
  
  黒瀬光一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Tokyo University of Marine Science and Technology
Development of a novel in vitro skin sensitization assay with predictive ability comparable to animal studiesPrincipal Investigator
- Principal Investigator
  
  黒瀬光一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Tokyo University of Marine Science and Technology
Development of detection method for potential food allergensPrincipal Investigator
- Principal Investigator
  
  Kurose Kouichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Tokyo University of Marine Science and Technology
Utilaization of isopod as a foodstuff
- Principal Investigator
  
  Kazufumi Osako
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Aquatic life science
- Research Institution
  Tokyo University of Marine Science and Technology
A new evaluation method for allergenicity of food proteinsPrincipal Investigator
- Principal Investigator
  
  Kurose Kouichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Tokyo University of Marine Science and Technology
Development of an in vitro allergenicity test metod for drugs considered metabolic activationPrincipal Investigator
- Principal Investigator
  
  KUROSE Kouichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Marine Science and Technology
  National Institute of Health Sciences
Mechanistic analysis and prediction of infusion reactions
- Principal Investigator
  
  SAITO Yoshiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Association of genotypes for drug-binding protein with anti-cancer drug responses
- Principal Investigator
  
  SAI Kimie
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
内分泌攪乱物質によって発生初期に発現異常を示す遺伝子群のプロファイリングPrincipal Investigator
- Principal Investigator
  
  黒瀬光一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  国立公衆衛生院
IDENTIFICATION OF NUCLEAR FACTOR THAT ACTIVATED THE XRE-MEDIATED GENE TRANSCRIPTION
- Principal Investigator
  
  TOHKIN Masahiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  NATIONAL INSTITUTE OF PUBLIC HEALTH

All 2023 2019 2018 2017 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] 市販後安全性確保に係るバイオマーカーと診断2013
- Author(s)
  斎藤嘉朗, 前川京子, 田島陽子, 児玉進, 黒瀬光一
- Journal Title
  
  レギュラトリーサイエンス学会誌
  
  Volume: 3 Pages: 43-55
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] 副作用バイオマーカーの探索と臨床応用研究の現状について2013
- Author(s)
  斎藤嘉朗, 中村亮介, 黒瀬光一
- Journal Title
  
  臨床病理レビュー
  
  Volume: 150 Pages: 27-33
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] Genetic polymorphisms of FCGR2A encoding Fcγ receptor IIa in a Japanese population and functional analysis of the L273P variant2012
- Author(s)
  Tada M, Ishii-Watabe A, Maekawa K, Fukushima-Uesaka H, Kurose K, Suzuki T, Kaniwa N, Sawada J, Kawasaki N, Nakajima TE, Kato K, Yamada Y, Shimada Y, Yoshida T, Ura T, Saito M, Muro K, Doi T, Fuse N, Yoshino T, Ohtsu A, Saijo N, Okuda H, Hamaguchi T, Saito Y, Matsumura Y
- Journal Title
  
  Immunogenetics
  
  Volume: 64 Pages: 869-877
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients2011
- Author(s)
  Katori N, Sai K, Saito Y, Fukushima-Uesaka H, Kurose K,(fifteen other co-authors)
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 100 Pages: 4546-4559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] RNA-Seqを用いた網羅的な遺伝子発現解析による感作性評価マーカーの探索2023
- Author(s)
  Peiqi Zhai, 前田彩実, 小山寛喜, 黒瀬光一
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K02070
[Presentation] タンパク質のin vitroアレルゲン性評価法の開発　～LPSの影響の排除～2019
- Author(s)
  平田義明、田代康介、黒瀬光一
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K02220
[Presentation] オオグソクムシトロポミオシンの潜在的アレルゲン性とcDNAクローニング2018
- Author(s)
  岩川織奈、嶋倉邦嘉、紀藤圭治、大迫一史、黒瀬光一
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07869
[Presentation] タンパク質のin vitroアレルゲン性評価法の開発　～THP-1細胞におけるアレルゲン応答性の経時的変化～2018
- Author(s)
  和田旺子、阪下広海、黒瀬光一
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K02220
[Presentation] Study on the fatty acid compositions of deep-sea isopod Bathynomus doederleinii2017
- Author(s)
  T. Sawasaki, K. Takahashi, K. Kurose, E. Okazaki, K. Osako
- Organizer
  日本水産学会創立85周年記念国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07869
[Presentation] THP-1由来樹状細胞様細胞のアレルゲン応答性2017
- Author(s)
  大岩亮介、嶋倉邦嘉、中村亮介、黒瀬光一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K00812
[Presentation] アレルゲン特異的応答性を高めたTHP-1細胞由来細胞の作製2017
- Author(s)
  舞沢友昭、嶋倉邦嘉、黒瀬光一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K00812
[Presentation] 培養細胞を用いたアレルゲン性評価法の開発2017
- Author(s)
  大岩亮介・嶋倉邦嘉・中村亮介・黒瀬光一
- Organizer
  日本水産学会
- Place of Presentation
  東京
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-15K00812
[Presentation] THP-1細胞由来アレルゲン応答細胞の特性解析2017
- Author(s)
  阪下広海、大岩亮介、舞沢友昭、嶋倉邦嘉、黒瀬光一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K00812
[Presentation] Human Cell Line Activation Test （h-CLAT）の医薬品のアレルゲン性評価試験法としての応用2013
- Author(s)
  宇梶真帆、杉山永見子、中村亮介、斎藤嘉朗、打田光宏、土屋敏行、黒瀬光一
- Organizer
  第20回日本免疫毒性学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590157
[Presentation] ヒト試料を用いたバイオマーカー研究の現状と問題点2012
- Author(s)
  斎藤嘉朗, 前川京子, 佐井君江, 鹿庭なほ子, 黒瀬光一
- Organizer
  第33回日本臨床薬理学会学術総会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] パクリタキセル投与患者におけるα-1-acid glycoproteinと遺伝子多型、薬物動態および患者背景因子の関連性2011
- Author(s)
  香取典子、佐井君江、斎藤嘉朗、福島(上坂)浩美、黒瀬光一(他12名)
- Organizer
  日本薬学会第131年回
- Place of Presentation
  ツインメッセ静岡(静岡)
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] 日本人癌患者のORM遺伝子多型による血中α-1-酸性糖蛋白レベルへの影響2010
- Author(s)
  香取典子、佐井君江、斎藤嘉朗、福島(上坂)浩美、黒瀬光一、(他12名)
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮ソニックシティ(埼玉)
- Data Source
  KAKENHI-PROJECT-21590191

1. SAITO Yoshiro (50215571)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. SAI Kimie (20195960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KATORI Noriko (60142121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. ISHII Akiko (50291117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KATO Ken (50501855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NAKAMURA Ryosuke (50333357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. TADA Minoru (50506954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. SUGIYAMA Emiko (40574695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TOHKIN Masahiro (00270629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Kazufumi Osako (00452045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Kurose Kouichi 黒瀬 光一

KUROSE Koichi 黒瀬 光一

KUROSE Kouichi 黒瀬 光一

Research Projects

Research Products

Co-Researchers

カブトガニを救う新規エンドトキシン試験法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel in vitro skin sensitization assay with predictive ability comparable to animal studiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of detection method for potential food allergensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Utilaization of isopod as a foodstuff

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new evaluation method for allergenicity of food proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an in vitro allergenicity test metod for drugs considered metabolic activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanistic analysis and prediction of infusion reactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association of genotypes for drug-binding protein with anti-cancer drug responses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内分泌攪乱物質によって発生初期に発現異常を示す遺伝子群のプロファイリングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IDENTIFICATION OF NUCLEAR FACTOR THAT ACTIVATED THE XRE-MEDIATED GENE TRANSCRIPTION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 市販後安全性確保に係るバイオマーカーと診断2013

Author(s)

Journal Title

Data Source

[Journal Article] 副作用バイオマーカーの探索と臨床応用研究の現状について2013

Author(s)

Journal Title

Data Source

[Journal Article] Genetic polymorphisms of FCGR2A encoding Fcγ receptor IIa in a Japanese population and functional analysis of the L273P variant2012

Author(s)

Journal Title

Data Source

[Journal Article] Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients2011

Author(s)

Kurose Kouichi 黒瀬光一

KUROSE Koichi 黒瀬光一

KUROSE Kouichi 黒瀬光一

[Presentation] タンパク質のin vitroアレルゲン性評価法の開発　～LPSの影響の排除～2019

[Presentation] オオグソクムシトロポミオシンの潜在的アレルゲン性とcDNAクローニング2018

[Presentation] タンパク質のin vitroアレルゲン性評価法の開発　～THP-1細胞におけるアレルゲン応答性の経時的変化～2018