Itoh Kouichi 伊藤康一

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ITOH Kouichi 伊藤康一

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Researcher Number	30291149
Other IDs
External Links
Affiliation (Current)	2025: 徳島文理大学, 薬学部, 特別研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 徳島文理大学, 薬学部, 特別研究員 2021 – 2022: 徳島文理大学, 薬学部, 教授 2014 – 2019: 徳島文理大学, 薬学部, 教授 2005 – 2012: 徳島文理大学, 薬学部, 教授 2005 – 2008: 徳島文理大学, 香川薬学部, 教授 … More 2003: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 2003: TOKUSHIMA BUNRI UNIVERSITY, FUCULTY OF PHARMACEUTICAL SCIENCES AT KGAWA CAMPUS, 香川薬学部, 教授 2000 – 2002: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 2001: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1999: The Tokyo Metropolitan Institute of Medical Science, Department of Molecular Biodynamics, 東京都臨床医学総合研究所, 研究員 1998: 東京都臨床医学総合研究所, 炎症研究部門, 研究員 1998: 財団法人東京都臨床医学総合研究所, 炎症研究部門, 研究員 1997: (財)東京都臨床医学総合研究所, 炎症研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator Natural medicines / Biological pharmacy / Basic Section 47060:Clinical pharmacy-related / Neuroscience in general / Neurochemistry/Neuropharmacology Except Principal Investigator Radiation science / Psychiatric science / Cell biology / Basic Section 52030:Psychiatry-related / Basic Section 47060:Clinical pharmacy-related … More / Medical pharmacy / Functional biochemistry / Biological pharmacy / Measurement engineering Less
Keywords	Principal Investigator てんかん / ミクログリア / 脳波 / PTZ / nNOS / trk / MRI / 五苓散 / 脳内炎症 / 脳浮腫 … More / 漢方薬 / ユビキチン / 神経接着分子 / 児脳発達 / 周産期 / 抗てんかん / 補完療法 / ビデオ脳波 / DHA / マウス / ペンチレンテトラゾール / 小児 / ドコサヘキサエン酸 / 熱性けいれん / 疾患モデル / FACS / サイトカイン / 重積発作 / 血液脳関門 / Neural Cell Adhesion Molecules / Proteosome / Epilepsy / NOS inhibitors / NO / キンドリング / NOS阻害 / プロテアソーム / NOS阻害薬 / 一酸化窒素 / Cell culture / Neural cell adhesion molecule L1 / Axon / Oligodendrocyte / Myelin / 細胞培養 / 神経接着分子L1 / 神経軸索 / オリゴデンドロサイト / ミエリン / ELECTRICAL STIMULATION / MOUSE / CELL CULTURES / DRG NEURONS / NEUROTROPHIC FACTORS / NEURAL CELL ADHESION MOLECULES / NEURONAL ACTIVITY / Nervous system / cell adhesion Molecule / plasticity / Nervous System / Brain / LTP / Cell Adhesion Molecules / Plasticity / Neuron / Electrical stimulation / Mouse / Cell cultures / DRG neurons / Neurotrophic factors / Neural cell adhesion molecules / neuronal activity / てんかん原性 / 側頭葉てんかんモデルマウス / 血管原性脳浮腫 / 予防 / BBB / 細胞内輸送 / 神経科学 / 脳・神経 … More Except Principal Investigator MRI / ESR / 神経細胞 / 認知症 / てんかん / イメージング / NGF / ERK / phosphatidylethanolamine / yeast / actin / membrane / lipid bilayer / cytoskeleton / phospholipid / ホスファチジルエタノールアミン / 酵母 / アクチン / 細胞膜 / 脂質二重層 / 細胞骨格 / リン脂質 / 修復 / 無血清培地 / アストロサイト / 脆弱性 / 分化 / DNA損傷修復 / NER / オリゴデンドロサイト / 酸化ストレス / 活性酸素 / 一酸化窒素 / 細胞・組織 / 可視化 / 脳血管関門 / 血液脳関門 / アルツハイマー型認知症 / 脳内炎症 / CAGE / レベチラセタム / 脳卒中 / 老年精神医学 / 血液脳関門不全 / アルツハイマー病 / COX-2 / ADAMTS4 / マトリックスメタロプロテアーゼ / リゾリン脂質 / リゾホスファチジン酸 / プロトン感知性受容体 / 滑膜細胞 / 関節リウマチ / protein / cell / visualization / ESRI / 蛋白質 / タンパク質 / 細胞 / Signal transduction / Neuronal adhesion molecule / Cerebellar granule cells / PC 12 cells / Neurite / Phospholipase D / 一級アルコール / 神経細胞接着分子 / 軸索伸長 / 小脳顆粒細胞 / シグナル伝達 / 神経接着分子 / 小脳果顆粒細胞 / PC12細胞 / 神経軸策 / ホスホリパーゼD / cell polarity / 分裂溝 / 細胞分裂 / 上皮細胞 / 細胞極性 / フリップ-フロップ / neuron / 変異株 / 変異体 / マクチン / ニューロン / 一酸化窒素(NO) / 神経型一酸化窒素合成酵素 / ペンチレンテトラゾール / SUMO / 全般てんかん / small ubiquitin-related modifier (SUMO) / ペンチレンテトラゾール (PTZ) / 一酸化窒素合成酵素 (nNOS) / 一酸化窒素 (NO) / 神経薬理学 / 酸素 / 生理機能 / 高速計測 / 非侵襲 / EPR / 電子常磁性共鳴 / 無血清 / UV / NT-3 / PDGF / 老化 / DNA損傷 / アウトロサイト / プローベ / 分子イメージング / フリーラジカル / 電子スピン共鳴分光 / スライス選択画像 / 脳 / 共振器 / 電子スピン共鳴イメージング / 高速化 / マウス / 画像再構成 / スライス選択 / 電子スピン共鳴 / 磁気 / 移植・再生医療 / 移植細胞 / 磁気標識 Less

高齢者で急増する脳卒中後てんかん発症予防に有効な薬物療法の確立へ向けた基礎研究
- Principal Investigator
  
  小森理絵
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokushima Bunri University
小動物用MRIを用いたアルツハイマー病モデルマウスにおける血液脳関門に関する研究
- Principal Investigator
  
  中村祐
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kagawa University
Basic research on complementary DHA intake therapy to reduce the risk of infant brain developmentPrincipal Investigator
- Principal Investigator
  
  Itoh Kouichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokushima Bunri University
Suppressive effects of GOREI-SAN (Kampo) for brain edema and inflammatory response in acute phase after status epilepticusPrincipal Investigator
- Principal Investigator
  
  Kouichi itoh
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Tokushima Bunri University
Study of the relation between Alzheimer's disease and BBB disfunctions using MRI for small animals
- Principal Investigator
  
  Nakamura Yu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kagawa University
Analysis of the molecular mechanism by which extracellular acidification promotes LPA-induced inflammatory responses in rheumatoid arthritis synovial cells.
- Principal Investigator
  
  Nochi Hiromi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokushima Bunri University
A new strategy for epilepsy therapy and Kampo: Focusing on preventing brain edema in basic researchPrincipal Investigator
- Principal Investigator
  
  Itoh Kouichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Tokushima Bunri University
Functional molecular imaging studies by rapid EPR imaging method
- Principal Investigator
  
  FUJII Hirotada
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
A study on the roles of nNOS-SUMO-1 conjugation and NO-nNOS machinery in PTZ-induced convulsive seizure
- Principal Investigator
  
  WATANABE Masatomo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokushima Bunri University
Vulnerability of Oligodendrocytes to DNA damages-Association with AD-
- Principal Investigator
  
  NAKAMURA Yuu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kagawa University
Functional imaging studies of small rodents by ESR・MRI combined system
- Principal Investigator
  
  FUJII Hirotada
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Spatiotemporal Regulation of Rabex-5 in Endocytic Trafficking of K63-linked Polyubiquitination of L1CAMPrincipal Investigator
- Principal Investigator
  
  ITOH Kouichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokushima Bunri University
Vulnerability of oligodendrocyte to DNA damages-Association with aging and dementia-
- Principal Investigator
  
  NAKAMURA Yu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kagawa University
Electron spin resonance imaging for brain/neuroscience studies
- Principal Investigator
  
  HIRATA Hiroshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Measurement engineering
- Research Institution
  Hokkaido University
  Yamagata University
ESR・MRI磁気共鳴法による移植細胞動態の新規追跡システム
- Principal Investigator
  
  FUJII Hirotada
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Molecular magnetic resonance imaging studies on ESR・MRI dual system
- Principal Investigator
  
  FUJII Hirotada
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Stability of nNOS in generalized epilepsyPrincipal Investigator
- Principal Investigator
  
  ITOH Kouichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokushima Bunri University
STUDY ON FUNCTION OF PHOSPHOLIPASE D2 IN NEURITE REMODELING
- Principal Investigator
  
  KANAHO Yasunori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH
Molecular mechanisms of bidirectional axon- oligodendrocytes signaling during the initial stages of myelinationPrincipal Investigator
- Principal Investigator
  
  ITOH Kouichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Metropolitan Medical Research Organization
Identification of phospholipid translocase and its role in cell polarity formation.
- Principal Investigator
  
  UMEDA Masato
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Membrane phospholipid dynamics and cytoskeletal organization: Regulation of actin filament assembly by redistribution of membrane surface phospholipid
- Principal Investigator
  
  UMEDA Masato
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ACTIVITY-DEPENDENT REGULATION OF NEURAL CELL ADHESION MOLECULES, NEUROTROPHINS AND THEIR RECEPTORS IN NEURONS.Principal Investigator
- Principal Investigator
  
  ITOH Kouichi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH

[Journal Article] Suppressive Effects of Docosahexaenoic Acid Intake on Increased Seizure Susceptibility after Growth Due to Febrile Seizures in Infancy2023
- Author(s)
  Kawano Shinji、Itoh Kouichi、Ishihara Yasuhiro
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 9 Pages: 1184-1193
- DOI
  10.1248/bpb.b23-00015
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06702
[Journal Article] Maternal intake of docosahexaenoic acid decreased febrile seizure sensitivity by increasing estrogen synthesis in offspring2021
- Author(s)
  Kawano Shinji、Itoh Kouichi、Ishihara Yasuhiro
- Journal Title
  
  Epilepsy & Behavior
  
  Volume: 121 Pages: 108038-108038
- DOI
  10.1016/j.yebeh.2021.108038
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H05510, KAKENHI-PROJECT-21K06702
[Journal Article] Suppressive effects of levetiracetam on neuroinflammation and phagocytic microglia: A comparative study of levetiracetam, valproate and carbamazepine2019
- Author(s)
  Itoh Kouichi、Taniguchi Ruri、Matsuo Taira、Oguro Ami、Vogel Christoph F.A.、Yamazaki Takeshi、Ishihara Yasuhiro
- Journal Title
  
  Neuroscience Letters
  
  Volume: 708 Pages: 134363-134363
- DOI
  10.1016/j.neulet.2019.134363
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356, KAKENHI-PROJECT-17K15533
[Journal Article] Neuroprotective activation of astrocytes by methylmercury exposure in the inferior colliculus2019
- Author(s)
  Ishihara Yasuhiro、Itoh Kouichi、Oguro Ami、Chiba Yoichi、Ueno Masaki、Tsuji Mayumi、Vogel Christoph F. A.、Yamazaki Takeshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 13899-13899
- DOI
  10.1038/s41598-019-50377-9
- NAID
  120006799369
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07508, KAKENHI-PROJECT-17H04714, KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356
[Journal Article] Progression of vasogenic edema induced by activated microglia under permanent middle cerebral artery occlusion.2018
- Author(s)
  Tanaka M, Ishihara Y, Mizuno S, Ishida A, Vogel CFA, Tsuji M, Yamazaki T, Itoh K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496(2) Issue: 2 Pages: 582-587
- DOI
  10.1016/j.bbrc.2018.01.094
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356, KAKENHI-PROJECT-18K05357
[Journal Article] Potentiation of 17β-estradiol synthesis in the brain and elongation of seizure latency through dietary supplementation with docosahexaenoic acid.2017
- Author(s)
  Ishihara Y, Itoh K, Tanaka M, Tsuji M, Kawamoto T, Kawato S, Vogel CFA, Yamazaki T
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1): Issue: 1 Pages: 6268-6268
- DOI
  10.1038/s41598-017-06630-0
- NAID
  120006782321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00569, KAKENHI-PROJECT-17K08356
[Journal Article] Levetiracetam treatment influences blood-brain barrier failure associated with angiogenesis and inflammatory responses in the acute phase of epileptogenesis in post-status epilepticus mice2016
- Author(s)
  Kouichi Itoh, Yasuhiro Ishihara, Rie Komori, Hiromi Nochi, Ruri Taniguchi, Yoichi Chiba, Masaki Ueno, Fuyuko Takata-Tsuji, Shinya Dohgu, Yasufumi Kataoka
- Journal Title
  
  Brain Research
  
  Volume: 1652 Pages: 1-13
- DOI
  10.1016/j.brainres.2016.09.038
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460139, KAKENHI-PROJECT-15K08122, KAKENHI-PROJECT-15K18947
[Journal Article] Alterations in Rapid Eye Movement Sleep Parameters Predict for Subsequent Progression from Mild Cognitive Impairment to Alzheimer's Disease2016
- Author(s)
  Hideto Shinno, Ichiro Ishikawa, Nobuo Ando ,Yoshihito Matsumura, Jun Horiguchi, and Yu Nakamura
- Journal Title
  
  Journal of Alzheimer’s Disease & Parkinsonism
  
  Volume: Volume6 Issue2 Issue: 02
- DOI
  10.4172/2161-0460.1000218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10216
[Journal Article] Prevention of status epilepticus-induced brain edema and neuronal cell loss by repeatedtreatment with high-dose levetiracetam2015
- Author(s)
  ・Itoh, K., Inamine, M., Oshima, W., Kotani, M., Chiba, Y., Ueno, M., Ishihara, Y
- Journal Title
  
  Brain Reasaech
  
  Volume: 1608 Pages: 225-234
- DOI
  10.1016/j.brainres.2015.03.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460139
[Journal Article] The threshold of pentylenetetrazole-induced convulsive seizures, but not that of nonconvulsive seizures, is controlled by the nitric oxide levels in murine brains2013
- Author(s)
  Watanabe M, Miyai A, Danjo S, Nakamura Y, Itoh K
- Journal Title
  
  Experimental Neurology
  
  Volume: (in press) Pages: 645-652
- DOI
  10.1016/j.expneurol.2013.02.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590095
[Journal Article] Noninvasive mapping of the redox status in septic mouse by in vivo electron paramagnetic resonance imaging.2013
- Author(s)
  Fujii HG, Sato-Akaba H, Emoto MC, ItohK, Ishihara Y, Hirata H.
- Journal Title
  
  Magn Reson Imag
  
  Volume: 31 Pages: 130-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390236
[Journal Article] Effects of Sulfaphenazole after Collagenase-Induced Experimental Intracerebral Hemorrhage in Rats2012
- Author(s)
  Hama S, Ishihara Y, Watanabe M, Danjo S, Nakamura Y, Itoh K
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 10 Pages: 1849-1853
- DOI
  10.1248/bpb.b12-00525
- NAID
  130001872384
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590095
[Journal Article] A novel ascorbic acid-resistant nitroxide in fat emulsion is an efficient brain imaging probe for in vivo EPR imaging of mouse.2011
- Author(s)
  Emoto M, Mito F, Yamasaki T, Yamada K, Sato-Akaba H, Hirata H, Fujii H.
- Journal Title
  
  Free Radic Res.
  
  Volume: 45 Pages: 1325-1332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390236
[Journal Article] Characterization of a novel posttranslational modification in neuronal nitric oxide synthase by small ubiquitin-related modifier-12011
- Author(s)
  Masatomo Watanabe, Kouichi Itoh
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590095
[Journal Article] Human L1CAM carrying the missense mutations of the fibronectin-like type IIIdomains is localized in the endoplasmic reticulum and degraded by polyubiquitylation2011
- Author(s)
  Itoh K, Fujisaki K, Watanabe M
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 89 Issue: 10 Pages: 1637-1645
- DOI
  10.1002/jnr.22695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590095
[Journal Article] Simultaneous molecular imaging based on electron paramagnetic resonance of 14Nand 15N-labelled nitroxyl radicals.2011
- Author(s)
  Pawlak A, Ito R, Fujii H, Hirata H.
- Journal Title
  
  Chem Comm.
  
  Volume: 47 Pages: 3245-3247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390236
[Journal Article] Characterization of a novel posttranslational modification in neuronal nitric oxide synthase by small ubiquitin-related modifier-12011
- Author(s)
  Watanabe M, Itoh K
- Journal Title
  
  Biochem Biophys Acta
  
  Volume: 1814 Issue: 7 Pages: 900-907
- DOI
  10.1016/j.bbapap.2011.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590095
[Journal Article] Resolution recovery for EPR imaging of free radical molecules in mice2009
- Author(s)
  Y. Ikebata, H. Sato-Akaba, T. Aoyama, H. Fujii, K. Itoh, H. Hirata
- Journal Title
  
  Magnetic Resonance in Medicine (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360194
[Journal Article] Resolution-recovery for EPR imaging of free radical molecules in mice.2009
- Author(s)
  Ikebata Y, Sato-Akaba H, Aoyama T, Fujii H, Itoh K, Hirata H
- Journal Title
  
  Magn Reson Med 62
  
  Pages: 788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390322
[Journal Article] Early postnatal ethanol exposure induces fluctuation in the expression of BDNF mRNA in the developing rat hippocampus2008
- Author(s)
  Miki T, Kuma H, Yokoyama T, Sumitani K, Matsumoto Y, Kusaka T, Warita K, Wang ZY, Hosomi N, Imagawa T, S Bedi K, Itoh S, Nakamura Y, Takeuchi Y
- Journal Title
  
  Acta Neurobiol Exp(Wars) 68(4)
  
  Pages: 484-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591358
[Journal Article] The entry of manganese ions into the brain is accelerated by the activation of N-methyl-D-aspartate receptors.2008
- Author(s)
  Itoh K, Sakata M, Watanabe M, Aikawa Y, Fujii H
- Journal Title
  
  Neuroscience 154
  
  Pages: 732-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390322
[Journal Article] Measurement of brain tissue oxygenation under oxidative stress by EPR/MRI dual system2007
- Author(s)
  H.Fujii, K.Itoh, R.P. Pandian, M.Sakata, Kuppusamy P, and H.Hirata
- Journal Title
  
  Mag.Res.Med.Sci 6
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590093
[Journal Article] 小動物MRIの創薬への応用2007
- Author(s)
  伊藤康一、藤井博匡
- Journal Title
  
  脳21 10
  
  Pages: 190-196
- Data Source
  KAKENHI-PROJECT-19590093
[Journal Article] Flow cytometric analysis of mouse neurospheres based on the expression level of RANDAM-22007
- Author(s)
  M, Kotani, K.Itoh
- Journal Title
  
  Neurosic Lett 413
  
  Pages: 25-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590093
[Journal Article] Development of an ESR/MR Dual-imaging System as a Tool to Detect Bioradicals2006
- Author(s)
  H.Fujii, M.Aoki, T.Haishi, K.Itoh, M.Sakata
- Journal Title
  
  Mag.Res.Med.Sci. 5
  
  Pages: 17-23
- NAID
  10019168566
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Development of an ESR/MR Dual-imaging System as a Tool to Detect Bioradicals.2006
- Author(s)
  H.Fujii, M.Aoki, T.Haishi, K.Itoh, M.Sakata
- Journal Title
  
  Mag. Res. Med. Sci 5
  
  Pages: 17-23
- NAID
  10019168566
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Critical Role of PICT-1, a Tumor Suppressor Candidate, in Phosphatidylinositol 3, 4, 5-Trisphosphate Signals and Tumorigenic Transformation2006
- Author(s)
  F.Okahara, K.Itoh, A.Nakagawara, M.Murakami, Y.Kanaho, T.Maeham
- Journal Title
  
  Mol. Biol. Cell 17
  
  Pages: 4888-4895
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Monoclonal Antibody Rip Specifically Recognizes 2', 3'-cyclic nucleotide 3'-phosphodiesterase in Oligodendrocytes2006
- Author(s)
  M.Watanabe, Y.Sakurai, T.Ichinose, Y.Aikawa, M.Kotani, K.Itoh
- Journal Title
  
  J.Neurosci.Res. 84
  
  Pages: 525-533
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Monoclonal Antibody Rip Specifically recognizes 2',3'-cyclic nucleotide 3'-phosphodiesterase in Oligodendrocytes2006
- Author(s)
  M.Watanabe, Y.Sakurai, T.Ichinose, Y.Aikawa, M.Kotani, K.Itoh
- Journal Title
  
  J.Neurosci.Res. 84
  
  Pages: 525-533
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Critical Role of PICT-1, a Tumor Suppressor Candidate, in Phosphatidylinosito 3,4,5-Trisphosphate Signals and Tumorigenic Transformation2006
- Author(s)
  F.Okahara, K.Itoh, A.Nakagawara, M.Murakami, Y.Kanaho, T.Maeham
- Journal Title
  
  Mol.Biol.Cell. 17
  
  Pages: 4888-4895
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Monoclonal Antibody Rip Specifically Recognizes 2', 3'-cyclic nucleotide 3'-phosphodiesterase in Oligodendrocytes2006
- Author(s)
  M.Watanabe, Y.Sakurai, T.Ichinose, Y.Aikawa, M.Kotani, K.Itoh
- Journal Title
  
  J. Neurosci. Res. 84
  
  Pages: 525-533
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Critical Role of PICT-1, a Tumor Suppressor Candidate, in Phosphatidylinositol 3, 4, 5-Trisphosphate Signals and Tumorigenic Transformation2006
- Author(s)
  F.Okahara, K.Itoh.A.Nakagawara, M.Murakami, Y.Kanaho, T.Maehama
- Journal Title
  
  Mol.Biol.Cell 17
  
  Pages: 4888-4895
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Dephosphorylation of Neural Cell Adhesion Molecule L1 by Brief Theta Burst Stimulation to Induce LTP in Rat Hippocampus2005
- Author(s)
  K.Itoh, K.Shimono, V.Lemmon
- Journal Title
  
  Mol.Cell Neurosci. 29
  
  Pages: 245-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] L1 mediated branching is regulated by two ERM-binding sites -the YRSLE motif and a novel juxtamembrane ERM-binding region2005
- Author(s)
  L.Cheng, K.Itoh, V.Lemmon
- Journal Title
  
  J. Neurosci. 25
  
  Pages: 395-403
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] L1 mediated branching is regulated by two ERM-binding sites-the YRSLE motif and a novel juxtamembrane ERM-binding region2005
- Author(s)
  L.Cheng, K.Itoh, V.Lemmon
- Journal Title
  
  J.Neurosci. 25
  
  Pages: 395-403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Production of research-grade antibody by in vivo electroporation of DNA encoding target protein.2005
- Author(s)
  F.Okahara, K.Itoh, M.Ebihara, M.Kobayashi, H.Maruyama, Y.Kanaho, T.Maehama
- Journal Title
  
  Anal. Biochem. 336
  
  Pages: 138-140
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Journal Article] Dephosphorylation of Neural Cell Adhesion Molecule L1 by Brief Theta Burst Stimulation to Induce LTP in Rat Hippocampus2005
- Author(s)
  K.Itoh, K.Shimono, V.Lemmon
- Journal Title
  
  Mol. Cell Neurosci 29
  
  Pages: 245-249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590081
[Presentation] 熱性けいれん後てんかんマウスの作製とドコサヘキサエン酸(DHA)によるてんかん発症の予防2022
- Author(s)
  川野真慈、石原康宏、伊藤康一
- Organizer
  てんかん学会・第16回中四国支部会
- Data Source
  KAKENHI-PROJECT-21K06702
[Presentation] てんかん原性初期における遺伝子発現変動の網羅的解析2020
- Author(s)
  小森理絵、河野智海、小澤千尋、松尾平、石原康宏、伊藤康一
- Organizer
  日本薬学会140年会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] 重積発作後の脳内サイトカインストームと抗てんかん薬2019
- Author(s)
  伊藤康一、松尾　平、石原康宏
- Organizer
  第13回日本てんかん学会中国・四国地方会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] 重積発作後てんかん原性期における脳内浸潤白血球の解析2019
- Author(s)
  松尾平、中妻彩、小森理絵、伊藤康一
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] てんかん原性初期の脳内変化とてんかん発症に対する五苓散の効果2019
- Author(s)
  小森理絵、大江優美、石原康宏、松尾平、伊藤康一
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] てんかん原性形成における免疫細胞動態－サイトカインストームとの関連性－2018
- Author(s)
  伊藤康一、石原康宏
- Organizer
  生体機能と創薬シンポジウム2018
- Invited
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] てんかん原性初期における脳内炎症関連サイトカインのプロファイル2018
- Author(s)
  伊藤　康一、橋本律香、久保静香、松尾平、小森理絵、水野翔童、石原康宏
- Organizer
  日本薬学会第138 年会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] CAGE-seq法を用いた重積発作後てんかん原性初期の海馬内遺伝子変化2018
- Author(s)
  小澤千尋、河野智海、松尾平、小森理絵、伊藤康一
- Organizer
  第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] 重積発作後てんかん原性初期の海馬内脳内炎症関連遺伝子の解析2018
- Author(s)
  河野智海、小澤千尋、松尾平、小森理絵、伊藤康一
- Organizer
  第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] 症候性てんかん原性脳内における炎症関連分子発現プロファイリング2017
- Author(s)
  伊藤　康一、橋本律香、久保静香、松尾平、小森理絵、水野翔童、石原康宏
- Organizer
  第70回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17K08356
[Presentation] Status epileptics後に出現する脳浮腫に対する五苓散の効果2015
- Author(s)
  伊藤　康一、大江　優美、小森　理絵、石原　康宏
- Organizer
  香川脳神経研究会（第10回定例会）
- Place of Presentation
  ロイヤルパークホテル高松
- Year and Date
  2015-01-16
- Data Source
  KAKENHI-PROJECT-26460139
[Presentation] Blood-brain barrier leakage is transiently induced by activity-dependent excessive nitric oxide production2013
- Author(s)
  伊藤康一, 檀上園子, 石原康宏, 渡邊正知, 中村祐
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] Blood-brain barrier leakage is transiently induced by activity-dependent excessive nitric oxide production2013
- Author(s)
  伊藤康一 et al.
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] Mass spectrometric characterization of the glycosylation sites and pattern of neural cell adhesion molecule L1 expressed in murine brain2013
- Author(s)
  南知尋*, 渡邊正知, 伊藤康一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] The assessment of brain functions in the proconvulsants-provoked convulsive seizure model mice using magnetic resonance imaging2012
- Author(s)
  伊藤康一, 渡邊正知
- Organizer
  第46回日本てんかん学会
- Place of Presentation
  都市センターホテル(東京)
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] Anticonvulsant effects of AEDs against PTZ-induced generalized seizures are controlled by NO levels in mice brain2012
- Author(s)
  渡邊正知 , 宮井明日香 , 伊藤康一
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] The assessment of brain functions in the proconvulsants-provoked convulsive seizure model mice using magnetic resonance imaging2012
- Author(s)
  伊藤康一, 渡邊正知
- Organizer
  第46回日本てんかん学会
- Place of Presentation
  都市センターホテル（東京）
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] ガドリニウム増強磁気共鳴画像法を用いたPTZ誘発キンドリングマウスにおけるBBB損傷の解析2011
- Author(s)
  檀上園子,渡邊正知,鴻海俊太郎,中村祐,伊藤康一
- Organizer
  第45回日本てんかん学会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] ガドリニウム増強磁気共鳴画像法を用いたPTZ単回投与誘発発作モデルマウスにおけるBBB破綻の解析2011
- Author(s)
  伊藤康一,檀上園子,渡邊正知,鴻海俊太郎,中村祐
- Organizer
  第45回日本てんかん学会
- Place of Presentation
  朱鷺メッセ(新潟)
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] 神経活動依存的な生体内一酸化窒素(NO)発生量と痙攣発作との相関関係2010
- Author(s)
  宮井明日香、渡邊正知、鴻海俊太郎、伊藤康一
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2010
- Place of Presentation
  京都大学薬学部(京都)
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] Brain Barriers Disruption and Acute Seizures Kindling by Pentylenetetrazole in Mice2010
- Author(s)
  Itoh K
- Organizer
  Neuro 2010
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21591521
[Presentation] Characterization of a novel posttranslational modification in neuronal nitric oxide synthase by small ubiquitin-related modifier-1;2010
- Author(s)
  渡邊正知 , 宮井明日香, 伊藤康一
- Organizer
  SUMO-1、Neuro 2010
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] 神経活動依存的な生体内-酸化窒素(NO)発生量と痙攣発作との相関関係2010
- Author(s)
  宮井明日香、渡邊正知、鴻海俊太郎、伊藤康一
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2010
- Place of Presentation
  京都大学薬学部(京都)
- Data Source
  KAKENHI-PROJECT-22590095
[Presentation] EPRを用いた2分子同時イメージング法の基礎的実験-15N-TEMPOLとTAMを用いた実験-2009
- Author(s)
  伊藤良平
- Organizer
  SEST2009
- Place of Presentation
  神戸市
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-19390322
[Presentation] Superresolutiokn EPR Imaging : Phantom and Animal experiments2008
- Author(s)
  Y. Ikebata, H. Sato-Akaba, T. Aoyama,H. Fujii, K. Itoh, and H. Hirata
- Organizer
  6th Asia-Pacific EPR symposium, Cairns, Australia
- Place of Presentation
  Invited
- Year and Date
  2008-07-17
- Data Source
  KAKENHI-PROJECT-18360194
[Presentation] Rabex-5, a guanine exchange factor for Rab5, Regulates the Ubiquitin-dependent Endocytic Trafficking of Neural Cell Adhesion Molecule L12008
- Author(s)
  Y. Aikawa, Y. Shigemi, M. Watanabe, V. Lemmon, K. Itoh
- Organizer
  48rd Annual meeting, American Society for Cell Biology
- Place of Presentation
  サンフランシスコ・米国
- Data Source
  KAKENHI-PROJECT-19590093
[Presentation] Rabex-5, a guanine exchange factor for Rab5, Regulates the Ubiquitin-dependent Endocytic Trafficking of Neural Cell Adhesion Molecule L12008
- Author(s)
  Y. Aikawa, Y, Shigemi, M. Watanabe, V. Lemmon, K. Itoh
- Organizer
  48rd Annual meeting, American Society for Cell Biology
- Place of Presentation
  サンフランシスコ、米国
- Data Source
  KAKENHI-PROJECT-19590093
[Presentation] Molecular dynamics of cell adhesion molecule LI induced by theta burst stimulation in rat hippocampus2007
- Author(s)
  Y.Aikawa, M.Watanabe and K.Itoh
- Organizer
  第30回日本神経科学会・年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590093
[Presentation] Molecular dynamics of cell adhesion molecule L1 induced by theta burst stimulation in rat hippocampus2007
- Author(s)
  Y. Aikawa, M. Watanabe and K. Itoh
- Organizer
  第30 回日本神経科学会・年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590093
[Presentation] てんかん原性初期に発現する脳浮腫に対する五苓散の効果
- Author(s)
  大江優美、石原康宏、小森理絵、伊藤康一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  ザイン・クリエイティブセンター神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460139
[Presentation] てんかん原性の五苓散による予防的治療効果の可能性の検討
- Author(s)
  大江優美、稲嶺盛佳、川真田実来、小森理絵、石原康宏、伊藤康一
- Organizer
  第53回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  広島国際会議場
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-26460139

1. FUJII Hirotada (70209013)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
2. NAKAMURA Yu (70291440)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. HIRATA Hiroshi (60250958)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. 石原康宏 (80435073)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
5. WATANABE Masatomo (30306203)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
6. UMEDA Masato (10185069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KIDA Ikuhiro (60374716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MORI Toshio (10115280)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 今井秀記 (00558512)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 冨永貴志 (20344046)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. AIKAWA Yoshikatu (10412397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. KUMA Hiromi (90464362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAGASAKI Yukio (90198309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHSHIMA Takayuki (10397557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKEUCHI Ken-ichi (70270684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. EMOTO Kazuo (80300953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KANAHO Yasunori (00214437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SASAKI Takehiko (50333365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MAEHAMA Tomohiko (40322755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. WATANABE Hiroshi (80356261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Nochi Hiromi (30183552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 安藤延男 (80380161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 二宮貴至 (90363192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 亀井聖史 (60437671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 小森理絵 (70412400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. AKABA Hideo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. Tamoto Koichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. UENO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 山崎岳

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
30. 千葉陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Itoh Kouichi 伊藤 康一

ITOH Kouichi 伊藤 康一

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Basic research on complementary DHA intake therapy to reduce the risk of infant brain developmentPrincipal Investigator

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Suppressive effects of GOREI-SAN (Kampo) for brain edema and inflammatory response in acute phase after status epilepticusPrincipal Investigator

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A new strategy for epilepsy therapy and Kampo: Focusing on preventing brain edema in basic researchPrincipal Investigator

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Spatiotemporal Regulation of Rabex-5 in Endocytic Trafficking of K63-linked Polyubiquitination of L1CAMPrincipal Investigator

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Itoh Kouichi 伊藤康一

ITOH Kouichi 伊藤康一