IDO Akio 井戸章雄

Researcher Number	30291545
External Links
Affiliation (Current)	2023: 鹿児島大学, 医歯学域医学系, 教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 鹿児島大学, 医歯学域医学系, 教授 2014: 鹿児島大学, 医歯(薬)学総合研究科, 教授 2013: 鹿児島大学, 医歯(薬)学総合研究科, 教授(Professor) 2013: 鹿児島大学, 大学院・医歯学総合研究科, 教授 2012: 鹿児島大学, 医歯(薬)学総合研究科, 准教授 … More 2011 – 2012: 鹿児島大学, 大学院・医歯学総合研究科, 准教授 2010: 鹿児島大学, 医歯学総合研究科, 准教授 2007 – 2009: Kagoshima University, 大学院・医歯学総合研究科, 准教授 2005 – 2006: 京都大学, 医学研究科, 助教授 2003: Kyoto University Hospital, Department of Experimental Therapeutics, Translational Research Center, Associate professor, 大学院・医学研究科, 助教授 2002 – 2003: 京都大学, 医学研究科, 助教授 1997 – 2000: 宮崎医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 57070:Developmental dentistry-related / Gastroenterology / Gastroenterology / Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry / Hygiene and public health / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 肝再生 / マクロファージ / 肝障害 / 肝発癌 / 肝繊維化 / 肝癌 / 遺伝子治療 / 自然免疫 / オステオアクチビン / 炎症性発癌 … More / 急性冠不全 / 急性肝不全 / osteoactivin / 肝硬変 / ATBF1 / レトロウイルスレセプター / AFP遺伝子 / 腫瘍ワクチン / IL2遺伝子 / 肝不全 / ノックアウトマウス / 大腸炎 / 再生・修復 / ノックアウトマスウ / 再正・修復 / 四塩化炭素 / 貪食 / 組織修復 / 肝線維化 / 炎症生発癌 / 炎症性発がん / αフェトプロテイン / 低酸素 / 血管内皮増殖因子 / HSV-tk遺伝子 / ガンシクロビル / 自殺遺伝子 / 血管新生 / gene therapy / hepatoma / α-fetoprotein / hypoxia / VEGF / HSV-tk gene / gancyclovir / suicide gene / コリン欠乏アミノ酸置換食飼育ラット / 肝細胞癌 / 浸潤 / 転移 / 増殖因子 / choline deficient, L-amino acid-defined (CDAA) diet / haepatocarcinogenesis / hepatocellular carcinoma / liver cirrhosis / invasion / metastasis / growth factor / 転写因子 / 細胞増殖 / liver regeneration / hepatocarcinogenesis / Transcription factor / cell proliferation / 形質転換 / 肝細胞増殖因子 / M1 マクロファージ / M2 マクロファージ / 修復 / gpnmb / ディスバイオーシス / 腸内細菌 / 脂肪肝 … More Except Principal Investigator 胃食道逆流症 / ブラキシズム / 肝細胞増殖因子(HGF) / 肝細胞増殖因子 / 睡眠時ブラキシズム / ストレス / 食道内酸刺激 / 顎関節症 / HGF / HGF activator / 炎症性腸疾患 / 潰瘍性大腸炎 / NAFLD / MAPK / oval cell / 2-acethylaminofluorene / AFP / c-kit / 覚醒時ブラキシズム / 精神的ストレス / 胃食道逆流 / 咬筋活動 / HGF activator inhibitor / HCC / 肝硬変 / HAI-1 / 肝癌 / HGF activator inhibitor-1 / c-Met / 胃粘膜障害 / 線維芽細胞 / hepatocyte growth factor / 腸管粘膜再生 / DSS腸炎モデル / 組み換え型ヒトHGF / 劇症肝炎 / 遅発性肝不全 / プロテオーム解析 / SELDI-TOF MS / 二次元電気泳動 / 肝臓病学 / iPS細胞 / 肝細胞分化 / 上皮間葉転換 / 細胞移植 / tight juction protein / 細胞遊走 / epithelial restitution / 肺高血圧症 / 肝星細胞 / 腎メサンギウム細胞 / 臓器線維化 / プロテオミクス / C型慢性肝炎 / HCV / AIM / 補体C4断片 / ヒト好中球ペプチド / 膵炎 / 肝細胞癌 / 非アルコール性脂肪肝炎 / 膵癌 / 自己免疫性膵炎 / クローン病 / 脳腸相関 / 顎口腔機能 / 迷走神経 / 胃 / 食道 / 肝再生 / 初代培養肝細胞 / 増殖因子 / サイクリンD1 / 転写調節 / 転写因子 / 肝癌細胞 / 電気遺伝子導入法 / 遺伝子発現調節 / liver regeneration / hepatocyte / growth factor / cyclin D1 / transcription / 肝幹細胞 / 70%部分肝切除 / 抗体アレイ / c-Kit / ovall cell / oval cell分化 / 肝前駆細胞 / 骨髄細胞 / 分化 / 細胞増殖 / Hepatocyte Growth Factor (HGF) / hepatic stem cell / 70% partial hepatectomy / antibody array / 機能性ディスペプシア / 遺伝子多型 / プロトンポンプ阻害剤 / 脂肪肝 / 肝線維化 / NAFL / NAFLD発症 / 腹部超音波検査 / FIB4 index / 高血圧 / 分子疫学 / マイクロバイオーム / 口腔常在菌 / 大腸がん / 唾液 / 便 / 16S rRNA / 次世代シーケンサー / 口腔 / 大腸癌 / 大腸マイクロバイオーム / 口腔細菌叢 / 大腸フローラ / NGS / リスク診断 / 次世代シーケンス / 口腔内常在細菌叢 / メタゲノム解析 / 胃内の常在細菌叢 / 口腔内の常在細菌叢 / 咬筋 / 自律神経 / 胸焼け / 炎症反応 / 食道知覚 / 炎症性メディエーター / 症性メディエーターの動態 / 咀嚼筋障害 / 上部消化器疾患 / グレリン / 消化管運動 / GERD / 六君子湯 / 睡眠時ブラキシズム / プロバイオティクス / 腸内フローラ / ストレス物質 Less

The effects of small intestinal dysbiosis on hepatic steatosis and fibrosisPrincipal Investigator
- Principal Investigator
  
  井戸章雄
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagoshima University
非侵襲的な耳介迷走神経刺激は唾液分泌の促進とGERDとブラキシズムの抑制に有効か
- Principal Investigator
  
  宮脇正一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
胃食道逆流はなぜ咬筋活動を増加させるのか：ストレス物質に着目したメカニズムの解明
- Principal Investigator
  
  前田綾
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
消化管促進作用を有するグレリンの動態が睡眠時ブラキシズムに及ぼす影響の解明
- Principal Investigator
  
  高橋広太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
プロバイオティクスが覚醒時ブラキシズムと顎関節症に及ぼす影響の解明
- Principal Investigator
  
  大迫佑季
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
食道知覚過敏が中枢性感作を介してブラキシズムと顎関節症関連疼痛に与える影響の解明
- Principal Investigator
  
  大賀泰彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
新たな食道疾患の発症機序の解明：不正咬合と咀嚼筋障害に起因する口腔機能低下の影響
- Principal Investigator
  
  宮脇正一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
口腔・大腸マイクロバイオーム解析による大腸がんリスク診断および予防概念の創生
- Principal Investigator
  
  後藤雄一
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kagoshima University
胃内と口腔内の常在細菌叢、ブラキシズム及び胃食道逆流との関連性の解明
- Principal Investigator
  
  丸谷佳菜子
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
ストレスが食道の知覚過敏と覚醒時ブラキシズムに及ぼす影響の解明
- Principal Investigator
  
  福嶋美佳
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
炎症性メディエーターの動態が食道知覚の変化とブラキシズムの発症に与える影響の解明
- Principal Investigator
  
  前田綾
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
Metabolic switch of macrophages infiltrating injured liver, which regulates fibrosis and fibrolysis.Principal Investigator
- Principal Investigator
  
  Ido Akio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagoshima University
Molecular epidemiological study on the advancement of nonalcoholic fatty liver among general population.
- Principal Investigator
  
  IBUSUKI RIE
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kagoshima University
Effects of treatment of functional dyspepsia according to gene polymorphism on bruxism
- Principal Investigator
  
  Shouichi Miyawaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Kagoshima University
Effect of Gpnmb expressed in macrophages on repair of injured liver and hepatocarcinogenesisPrincipal Investigator
- Principal Investigator
  
  Ido Akio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagoshima University
The association between stmatognathic function and the sensation of the stomach and esophagus via brain activity
- Principal Investigator
  
  MIYAWAKI Shouichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kagoshima University
Using proteomics to elucidate pathogenesis and establish new diagnostic or treatment evaluation methods in refractory gastrointestinal diseases
- Principal Investigator
  
  TSUBOUCHI Hirohito
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagoshima University
Involvement of osteoactivin in inflammatory hepatocarcinogenesis: analysis of mice lacking osteoacitivin expressionPrincipal Investigator
- Principal Investigator
  
  IDO Akio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagoshima University
A role of hepatocyte growth factor in regulation of hepatic development and differentiation
- Principal Investigator
  
  TSUBOUCHI Hirohito
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagoshima University
Involvement of osteoactivin in hepatic injury and repairPrincipal Investigator
- Principal Investigator
  
  IDO Akio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagoshima University
プロテオーム解析による劇症肝炎でのHGFの生理機能の解明と新規分子マーカーの探索
- Principal Investigator
  
  TSUBOUCHI Hirohito
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kagoshima University
Involvement of ATBF1 in liver regeneration and hepatocarcinogenesisPrincipal Investigator
- Principal Investigator
  
  IDO Akio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
HGFを用いた炎症性腸疾患に対する粘膜再生療法の試み
- Principal Investigator
  
  HORI Takeshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  宮崎医科大学
Hepatocyte growth factor accelerates proliferation and differentiation of hepatic oval cells in a 2-acetylaminofluorene/partial hepatectomy model in rat
- Principal Investigator
  
  TSUBOUCHI Hirohito
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  宮崎医科大学
Functional analysis of osteoactivin and its role in hepatocarcinogenesisPrincipal Investigator
- Principal Investigator
  
  IDO Akio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
肝癌におけるHGF activator inhibitor発現の意義
- Principal Investigator
  
  弘野修一
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  宮崎医科大学
Gene therapy for hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  IDO Akio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Miyazaki Medical College
A transcriptional factor induced by HGF
- Principal Investigator
  
  TSUBOUCHI Hirohito
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Miyazaki Medical College
化学発癌ラットを用いた肝細胞癌に対する遺伝子導入と遺伝子治療Principal Investigator
- Principal Investigator
  
  井戸章雄
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  宮崎医科大学

[Book] 現場の疑問に答える肝臓病診療Q&A:我が国の劇症肝炎の実態はどうなっているのか2009
- Author(s)
  井戸章雄, 坪内博仁
- Total Pages
  4
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19209028
[Book] 劇症肝炎.消化器疾患最新の治療 : 286-290(2008)(菅野健太郎, 上西紀夫, 井廻道夫)2008
- Author(s)
  井戸章雄, 坪内博仁
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19590763
[Book] 肝細胞増殖因子(HGF); 臨床検査ガイド2009~2010, 192-193(2008)(和田攻, 大久保昭行, 矢崎義雄, 大内尉義(編集))2008
- Author(s)
  坪内博仁, 井戸章雄
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19590763
[Book] 劇症肝炎.肝疾患レジデントマニュアル第2版 : 211-219(2008)(柴田実, 八橋弘, 石川哲也(監修))2008
- Author(s)
  井戸章雄
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-19590763
[Book] 【分子消化器病】HGFはどのように抗アポトーシス機構とかかおるのか?2008
- Author(s)
  井戸章雄, 沼田政嗣, 坪内博仁.
- Total Pages
  7
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-19209028
[Book] 【からだの科学】肝臓病の最新治療(1)急性肝不全に対するHGF療法2008
- Author(s)
  井戸章雄, 坪内博仁.
- Total Pages
  4
- Publisher
  日本評論社
- Data Source
  KAKENHI-PROJECT-19209028
[Book] わが国の劇症肝炎の実態はどうなっているのか?. 現場の疑問に答える肝臓病診療Q&A2007
- Author(s)
  井戸章雄, 坪内博仁
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19209028
[Book] 劇症肝炎治療における血液浄化療法の有効性は?.臨床に直結する肝・胆・膵疾患治療のエビデンス : 133-135(2007)(跡見裕、上村直実、白鳥敬子、正木尚彦(編集))2007
- Author(s)
  井戸章雄, 桶谷真, 坪内博仁
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19590763
[Book] 第二章病態・病態生理病態生理.新しい診断と治療のABC50/消化器7肝癌 : 43-47(2007)坪内博仁(編集)(泉孝英、上島国利、祖父江元、垂井清一郎、千葉勉、千原和夫、藤井潤、正岡徹、丸茂文昭、宮坂信之(監修))2007
- Author(s)
  井戸章雄
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] Effects of intra‐oesophageal acid infusion and a stress task on masseter muscle activity and autonomic nervous activity in wakefulness2020
- Author(s)
  Maeda‐Iino Aya、Fukushima Mika、Sakoguchi Yoko、Omure Haruhito、Oishi Akihito、Oga Yasuhiko、Furukawa‐Sainoki Minami、Kanmura Shuji、Ido Akio、Miyawaki Shouichi
- Journal Title
  
  Journal of Oral Rehabilitation
  
  Volume: - Issue: 5 Pages: 567-576
- DOI
  10.1111/joor.12947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11946, KAKENHI-PROJECT-19K10409, KAKENHI-PROJECT-16K11791, KAKENHI-PROJECT-19K10390
[Journal Article] HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression2020
- Author(s)
  Nishikoba Nao、Kumagai Kotaro、Kanmura Shuji、Nakamura Yuko、Ono Mayumi、Eguchi Hiromi、Kamibayashiyama Tomomi、Oda Kohei、Mawatari Seiichi、Tanoue Shiroh、Hashimoto Shinichi、Tsubouchi Hirohito、Ido Akio
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 2135-2135
- DOI
  10.3389/fimmu.2020.02135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07976
[Journal Article] Evaluation of a Proton Pump Inhibitor for Sleep Bruxism: A Randomized Clinical Trial2016
- Author(s)
  H. Ohmure, K. Kanematsu-Hashimoto, K. Nagayama, H. Taguchi, A. Ido, K. Tominaga3, T. Arakawa, and S. Miyawaki
- Journal Title
  
  Journal of Dental Research
  
  Volume: 95 Issue: 13 Pages: 1479-1486
- DOI
  10.1177/0022034516662245
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05051, KAKENHI-PROJECT-15K11350, KAKENHI-PROJECT-26463114
[Journal Article] Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice2015
- Author(s)
  Kumagai K, Tabu K, Sasaki F, Takami Y, Morinaga Y, Mawatari S, Hashimoto S, Tanoue S, Kanmura S, Tamai T, Moriuchi A, Uto H, Tsubouchi H, Ido A.
- Journal Title
  
  PLoS One
  
  Volume: 10
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461013
[Journal Article] Expression of glycoprotein nonmetastatic melanoma protein B in macrophages infiltrating injured mucosa is associated with severity of experimental colitis in mice2015
- Author(s)
  Sasaki F, Kumagai K, Uto H, Takami Y, Kure T, Tabu K, Nasu Y, Hashimoto S, Kanmura S, Numata M, Moriuchi A, Sakiyama T, Tsubouchi H, Ido A
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 12
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461013
[Journal Article] Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C2014
- Author(s)
  Mera K, Uto H, Mawatari S, Ido A, Yoshimine Y, Nosaki T, Oda K, Tabu K, Kumagai K, Tamai T, Moriuchi A, Oketani M, Shimada Y, Hidaka M, Eguchi S, Tsubouchi H
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 14 Issue: 1 Pages: 27-27
- DOI
  10.1186/1471-230x-14-27
- NAID
  120006986648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Correlation of serum levels of complement C4a desArg with pathologically estimated severity of glomerular lesions and mesangial hypercellularity scores in patients with IgA nephropathy2013
- Author(s)
  Sogabe A, Uto H, Kanmura S, Nosaki T, Oyamada M, Tokunaga K, Nishida C, Fukumoto M, Oku M, Nishimoto K, Takenouchi S, Ido A, Shimada Y, Tsubouchi H
- Journal Title
  
  Int J Mol Med
  
  Volume: 32(2) Issue: 2 Pages: 307-14
- DOI
  10.3892/ijmm.2013.1390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Intractable Hepato-Biliary Diseases Study Group of Japan. Etiology and prognosis of fulminant hepatitis and late-onset hepatic failure in Japan:Summary of the annual nationwide survey between 2004 and 20092013
- Author(s)
  Oketani M, Ido A, Nakayama N, Takikawa Y, Naiki T, Yamagishi Y, Ichida T, Mochida S, Onishi S, Tsubouchi H
- Journal Title
  
  Hepatol Res
  
  Volume: 43 Issue: 2 Pages: 97-105
- DOI
  10.1111/j.1872-034x.2012.01105.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742
[Journal Article] Hepatitis C virus NS3/4A protease inhibits complement activation by cleaving complement component 42013
- Author(s)
  Mawatari S, Uto H, Ido A, Nakashima K, Suzuki T, Kanmura S, Kumagai K, Oda K, Tabu K, Tamai T, Moriuchi A, Oketani M, Shimada Y, Sudoh M, Shoji I, Tsubouchi H
- Journal Title
  
  PLoS One
  
  Volume: 8(12) Issue: 12 Pages: e82094-e82094
- DOI
  10.1371/journal.pone.0082094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043, KAKENHI-PROJECT-24390111
[Journal Article] Ibusuki R, Uto H, Arima S, Mawatari S, Setoguchi Y, Iwashita Y, Hashimoto S, Maeda T, Tanoue S, Kanmura S, Oketani M, Ido A, Tsubouchi H2013
- Author(s)
  Ibusuki R, Uto H, Arima S, Mawatari S, Setoguchi Y, Iwashita Y, Hashimoto S, Maeda T, Tanoue S, Kanmura S, Oketani M, Ido A, Tsubouchi H
- Journal Title
  
  L-amino acid-defined diet. Liver Int
  
  Volume: 33(10) Issue: 10 Pages: 1549-56
- DOI
  10.1111/liv.12203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Hepatocyte growth factor stimulates the migration of gastric epithelial cells by altering the subcellular localization of the tight junction protein ZO-12013
- Author(s)
  Nasu Y, Ido A, Tanoue S, Hashimoto S, Sasaki F, Kanmura S, Setoyama H, Numata M, Funakawa K, Moriuchi A, Fujita H, Sakiyama T, Uto H, Oketani M, Tsubouchi H
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Issue: 2 Pages: 193-202
- DOI
  10.1007/s00535-012-0615-y
- NAID
  10031156305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742, KAKENHI-PROJECT-23249043
[Journal Article] High serum thioredoxin levels are reduced after tonsillectomy in patients with IgA nephropathy2012
- Author(s)
  Nosaki T, Uto H, Takami Y, Oku M, Fukumoto M, Mera K, Nishida C, Tokunaga K, Sogabe A, Oketani M, Ido A, Kurono Y, Tsubouchi H
- Journal Title
  
  Intern Med
  
  Volume: 51(6) Pages: 559-65
- NAID
  130002061912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Human neutrophil peptide-1 aggravates dextran sulfate sodium-induced colitis2012
- Author(s)
  Hashimoto S, Uto H, Kanmura S, Sakiyama T, Oku M, Iwashita Y, Ibusuki R, Sasaki F, Ibusuki K, Takami Y, Moriuchi A, Oketani M, Ido A, Tsubouchi H
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 18(4) Issue: 4 Pages: 667-75
- DOI
  10.1002/ibd.21855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Clinical features of hepatitis C virus carriers with persistently normal alanine aminotransferase levels2012
- Author(s)
  Uto H, Mawatari S, Kumagai K, Ido A, Tsubouchi H
- Journal Title
  
  Hepat Mon
  
  Volume: 12(2) Issue: 2 Pages: 77-84
- DOI
  10.5812/hepatmon.829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Prevention of hepatitis B virus reactivation in patients receiving immunosuppressive therapy or chemotherapy2012
- Author(s)
  Oketani M, Ido A, Uto H, Tsubouchi H.
- Journal Title
  
  Hepatol Res
  
  Volume: 42 Issue: 7 Pages: 627-636
- DOI
  10.1111/j.1872-034x.2012.00998.x
- NAID
  10031144279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742, KAKENHI-PROJECT-23249043
[Journal Article] Difference in serum complement component C4a levels between hepatitis C virus carriers with persistently normal alanine aminotransferase levels or chronic hepatitis C2012
- Author(s)
  Imakiire K, Uto H, Sato Y, Sasaki F, Mawatari S, Ido A, Shimoda K, Hayashi K, Stuver SO, Ito Y, Okanoue T, Tsubouchi H
- Journal Title
  
  Mol Med Rep
  
  Volume: 6(2) Pages: 259-64
- DOI
  10.3892/mmr.2012.924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043, KAKENHI-PROJECT-23591397
[Journal Article] Liver regeneration after partial hepatectomy in rat is more impaired in a steatotic liver induced by dietary fructose compaired to dietary fat2011
- Author(s)
  Shirou Tanoue, Hirofumi Uto, Ryo Kumamoto, et al
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 407 Issue: 1 Pages: 163-168
- DOI
  10.1016/j.bbrc.2011.02.131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790673, KAKENHI-PROJECT-22590742, KAKENHI-PROJECT-23249043
[Journal Article] Highly sensitive lens culinaris agglutinin-reactive α-fetoprotein is useful for early detection of hepatocellular carcinoma in patients with chronic liver disease2011
- Author(s)
  Oda K, Hashiguchi T, 15番目, et al
- Journal Title
  
  Oncol Rep
  
  Volume: 26 Pages: 1227-1233
- DOI
  10.3892/or.2011.1425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390179, KAKENHI-PROJECT-23249043
[Journal Article] Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety.2011
- Author(s)
  Ido A, Moriuchi A, Numata M, Murayama T, Teramukai S, Marusawa H, Yamaji N, Setoyama H, Kim ID, Chiba T, Higuchi S, Yokode M, Fukushima M, Shimizu A. and Tsubouchi H.
- Journal Title
  
  J. Transl. Med.
  
  Volume: 9 Issue: 1 Pages: 55-55
- DOI
  10.1186/1479-5876-9-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390077, KAKENHI-PROJECT-21590592, KAKENHI-PROJECT-22590742
[Journal Article] Sorafenib and hepatic arterial infusion chemotherapy for unresectable advanced hepatocellular carcinoma : A comparative study2011
- Author(s)
  Hiramine Y, Uto H, Imamura Y, Tabu K, Baba Y, Hiwaki T, Sho Y, Tahara K, Higashi H, Tamai T, Oketani M, Ido A, Tsubouchi H
- Journal Title
  
  Exp Ther Med
  
  Volume: 2(3) Issue: 3 Pages: 433-441
- DOI
  10.3892/etm.2011.237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Serum manganese superoxide dismutase and thioredoxin are potential prognostic markers for hepatitis C virus-related hepatocellular carcinoma2011
- Author(s)
  Tamai T, Uto H, Takami Y, Oda K, Saishoji A, Hashiguchi M, Kumagai K, Kure T, Mawatari S, Moriuchi A, Oketani M, Ido A, Tsubouchi H
- Journal Title
  
  World J Gastroenterol
  
  Volume: 17 (44) Issue: 44 Pages: 4890-8
- DOI
  10.3748/wjg.v17.i44.4890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249043
[Journal Article] Changing etiologies and outcomes of acute liver failure: a perspective from Japan2011
- Author(s)
  Oketani M, Ido A, Tsubouchi H
- Journal Title
  
  J Gastroenterology Hepatol
  
  Volume: 26 Issue: s1 Pages: 65-71
- DOI
  10.1111/j.1440-1746.2010.06574.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742
[Journal Article] Repeated enemas with hepatocyte growth factor selectively stimulate epithelial cell proliferation of injured mucosa in rats with experimental colitis2011
- Author(s)
  Setoyama H, Ido A, Numata M, Moriuchi A, Yamaji N, Tamai T, Funakawa K, Fujita H, Sakiyama T, Uto H, Oketani M, Tsubouchi H
- Journal Title
  
  Life Sci
  
  Volume: 89 Pages: 269-275
- DOI
  10.3892/or.2011.1294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742
[Journal Article] Highly sensitive lens culinaris agglutinin-reactive alpha-fetoprotein is useful for early detection of hepatocellular carcinoma in patients with chronic liver disease2011
- Author(s)
  Oda K, Ido A, Tamai T, Matsushita M, Kumagai K, Mawatari S, Saishoji A, Kure T, Ohno K, Toyokura E, Imanaka D, Moriuchi A, Uto H, Oketani M, Hashiguchi T, Tsubouchi H
- Journal Title
  
  Oncol Rep
  
  Volume: 26 Pages: 1227-1233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742
[Journal Article] Thronbocytopenia exacerbates cholestasis-induced liver fibrosis in mice2010
- Author(s)
  Kodama T, Takehara T, Hikita H, Shimizu S, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Tadokoro S, Ido A, Tsubouchi H, Hayashi N
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Issue: 7 Pages: 2487-2498
- DOI
  10.1053/j.gastro.2010.02.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742
[Journal Article] Clinical significance of alanine aminotransferase levels and the effect of ursodeoxycholic acid in hemodialysis patients with chronic hepatitis C.2010
- Author(s)
  Nishida C, Uto H(2/11番目), Oketani M(3/11番目), Ido A(10/11番目), Tsubouchi H(11/11番目)
- Journal Title
  
  J Gastroenterol 45(3)
  
  Pages: 326-334
- NAID
  10027215180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] The complement component C3a fragment is a potential biomarker for hepatitis C virus-related hepatocellular carcinoma2010
- Author(s)
  Kanmura S, Uto H, Sato Y, Kumagai K, Sasaki F, Moriuchi A, Oketani M, Ido A, Nagata K, Hayashi K, Stuver SO, Tsubouchi H.
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Issue: 4 Pages: 459-467
- DOI
  10.1007/s00535-009-0160-5
- NAID
  10027215830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590742
[Journal Article] Proanthocyanidin derived from the leaves of Vaccinium virgatum suppresses platelet-derived growth factor-induced proliferation of the human hepatic stellate cell line LI902010
- Author(s)
  Takami Y, Uto H(2/11番目), Oketani M(8/11番目), Ido A(9/11番目), Tsubouchi H(11/11番目)
- Journal Title
  
  Hepatol Res 40(3)
  
  Pages: 337-345
- NAID
  10027407999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] Translational research to identify clinical applications of hepatocyte growth factor2009
- Author(s)
  Ido A, Tsubouchi H
- Journal Title
  
  Hepatol Res 39
  
  Pages: 739-747
- NAID
  10025326878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] Increased rate of death related to presence of viremia among hepatitis C virus antibody-positive subjects in a community-based cohort study Hepatology 20092009
- Author(s)
  Uto H, Stuver SO, Hayashi K, Kumagai K, Sasaki F, Kanmura S, Numata M, Moriuchi A, Hasegawa S, Oketani M, Ido A, Kusumoto K, Hasuike S, Nagata K, Kohara M, Tsugouchi H
- Journal Title
  
  (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] Human neutrophil peptide 1-3 are useful biomarkers in patients with active ulcerative colitis2009
- Author(s)
  Kanmura S, Uto H, Numata M, Hashimoto S, Moriuchi A, Fujita H, Oketani M, Ido A, Kodama M, Ohi H, Tsubouchi H
- Journal Title
  
  Inflamm Bowel Dis 15
  
  Pages: 909-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] Association of a genetic polymorphism in ectonucleotide pyrophosphatase/phophodiesterase 1 with hepatitis C virus infection and hepatitis C virus core antigen levels in subjects in a hyperendemic area of Japan2008
- Author(s)
  Takahama Y, Uto H, Kanmura S, Oketani M, Ido A, Kusumoto K, Hasuike S, Nagaa K, Hayashi K, Stuver S, Okayama A, Tsubouchi H
- Journal Title
  
  J Gastroenterology 43
  
  Pages: 942-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] Endoscopic characterization of the small bowels in patients with portal hypertension evaluated by double balloon endoscopy2008
- Author(s)
  Kodama M, Uto H, Numata M, Hori T, Murayama t, Sasaki F, Tsubouchi N, Ido A, Shimoda K, Tsubouchi H
- Journal Title
  
  J Gastroenterol 43
  
  Pages: 589-96
- NAID
  10021937551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] Translational research on HGF : A phase I/II study of recombinant human HGF for the treatment of fulminant hepaticfailure.2008
- Author(s)
  Ido A, Moriuchi A, et al.
- Journal Title
  
  Hepatol Res. S88-S92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] Endoscopic characterization of the small bowel in patients with portal hypertension evaluated by double balloon endoscopy.2008
- Author(s)
  Kodama M, Uto H(2/10番目) Ido A(8/10番目), Tsubouchi H(10/10番目)
- Journal Title
  
  J Gastroenterol 43(8)
  
  Pages: 589-596
- NAID
  10021937551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] Early diagnosis potential for hepatocellular carcinoma using the SELDI ProteinChip system2007
- Author(s)
  Kanmura S, Uto H, Kusumoto K, Ishida Y, Hasuike S, Nagata K, Hayashi K, Ido A, Stuver SO, Tsubouchi H
- Journal Title
  
  Hepatology 45
  
  Pages: 948-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] 非アルコール性脂肪肝炎(NASH)〜メタボリックシンドロームの一亜型2007
- Author(s)
  宇都浩文、桶谷真、井戸章雄、坪内博仁
- Journal Title
  
  実験医学 25
  
  Pages: 1375-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] Alanine aminotransferase flare-up in hepatitis C virus carriers with persistently normal alanine aminotransferase levels in a hyperendemic area of Japan.2007
- Author(s)
  Uto H(1/12番目), Ido A(6/12番目), Oketani M(11/12番目), Tsubouchi H(12/12番目)
- Journal Title
  
  J Gastroenterol 42(8)
  
  Pages: 673-680
- NAID
  10019817280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] Early diagnostic potential for hepatocellular carcinoma using the SELDI ProteinChip system.2007
- Author(s)
  Kanmura S, Uto H(2/10番目), Ido A(8/10番目), Tsubouchi H(10/10番目)
- Journal Title
  
  Hepatology 45(4)
  
  Pages: 948-956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209028
[Journal Article] Transgenic expression of osteoactivin in the liver attenuates hepatic fibrosis in rats2007
- Author(s)
  Abe H, Uto H, Takami Y, Takahama Y, Hasuike S, Kodama M, Nagata K, Moriuchi A, Numata M, Ido A, Tsubouchi H
- Journal Title
  
  Biochem Biophys Res Commun 356
  
  Pages: 610-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] Alanine aminotransferase flare-up in hepatitis C virus carriers with persistently normal alanine aminotransferase levels in a hyperendemic area of Japan2007
- Author(s)
  Uto H, Kurogi J, Takahama Y, Kusumoto K, Hayashi K, Ido A, Kohara M, Stuver SO, Moriuchi A, Hasegawa S, Oketani M, Tsubouchi H
- Journal Title
  
  J Gastroenterol 42
  
  Pages: 673-80
- NAID
  10019817280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590763
[Journal Article] Navigator-echo-based MR provides high-resolution Images and precise volumetry of swine livers without breath holding or injection of contrast media2006
- Author(s)
  Kim ID, Azuma T, Ido A, et al.
- Journal Title
  
  Liver Transplantation 12・1
  
  Pages: 72-77
- Data Source
  KAKENHI-PROJECT-17590636
[Journal Article] Hepatocyte growth factor facilitates the repair of large colonic ulcers in 2,4,6-trinitrobenzene sulfonic acid-induced colitis in rats2005
- Author(s)
  Numata M, Ido A, et al.
- Journal Title
  
  infalmmatory Bowel Disease 11・6
  
  Pages: 551-558
- Data Source
  KAKENHI-PROJECT-17590636
[Journal Article] Mucosal repair and growth factors : recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease.2005
- Author(s)
  Ido A, et al.
- Journal Title
  
  Journal of Gastroenterology 40
  
  Pages: 925-931
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590636
[Journal Article] The peroxisome proliferator-activated receptor-gamma agonist, pioglitazone, inhibits fat accumulation and fibrosis in the livers of rats fed a choline-deficient, 1-amino acid-defined diet2005
- Author(s)
  Uto H, Nakanishi C, Ido A, et al.
- Journal Title
  
  Hepatology Research 32・4
  
  Pages: 235-242
- Data Source
  KAKENHI-PROJECT-17590636
[Journal Article] Hepatocyte growth factor accelerates the proliferation of hepatic oval cells and possibly promotes the differentiation in a 2-acetylaminofluorene/partial hepatectomy model in rats2005
- Author(s)
  Hasuike S, Ido A, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology 20・11
  
  Pages: 1753-1761
- Data Source
  KAKENHI-PROJECT-17590636
[Journal Article] Development of a rapid semi-quantitative immunochromatographic assay for serum hepatocyte growth factor and its usefulness in acute liver failure2005
- Author(s)
  Uto A, Ido A, et al.
- Journal Title
  
  Hepatology Research 33・4
  
  Pages: 272-276
- NAID
  10016809896
- Data Source
  KAKENHI-PROJECT-17590636
[Journal Article] Mucosal repair and growth factors : recombinant human hepatocyte growth factor as an innovative therapy for inflammatory bowel disease2005
- Author(s)
  Ido A, Numata M, et al.
- Journal Title
  
  Journal of Gastroenterology 40・10
  
  Pages: 925-931
- Data Source
  KAKENHI-PROJECT-17590636
[Presentation] 覚醒時の食道内酸刺激は精神的ストレスより咬筋活動と自律神経活動に強く影響する．2021
- Author(s)
  福嶋　美佳，前田　綾，大牟禮　治人，迫口　陽子，大賀　泰彦，古川　みなみ，中川　祥子，大迫　佑季，高橋　広太郎，成　昌建，原田　真利那，上村　修司，井戸　章雄，宮脇　正一．
- Organizer
  第80回日本矯正歯科学会学術大会＆第５回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10409
[Presentation] 覚醒時の食道内酸注入は精神的ストレスより咬筋活動と自律神経活動により強く影響する .2021
- Author(s)
  福嶋美佳、前田綾、大牟禮治人、迫口陽子、大賀泰彦、古川みなみ、中川祥子、大迫佑季、髙橋広太郎、成昌建、原田真利那、上村修司、井戸章雄、宮脇正一 .
- Organizer
  第80回日本矯正歯科学会学術大会＆第5回国際会議
- Data Source
  KAKENHI-PROJECT-19K10390
[Presentation] 覚醒時の食道内酸刺激は精神的ストレスより咬筋活動と自律神経活動に強く影響する2021
- Author(s)
  福嶋　美佳，前田　綾，大牟禮　治人，迫口　陽子，大賀　泰彦，古川　みなみ，中川　祥子，大迫　佑季，高橋　広太郎，成　昌建，原田　真利那，上村　修司，井戸　章雄，宮脇　正一
- Organizer
  第80回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10232
[Presentation] Hepatic fibrosis and apoptosis induced by ethanol administration are exacerbated in human neutrophil peptide-1 transgenic mice2014
- Author(s)
  Ibusuki R, Uto H, Kozono M, Oda K, Ohshige A, Kumagai K, Mawatari S, Tamai T, Moriuchi A, Oketani M, Ido A, Tsubouchi H
- Organizer
  49th the international liver congress 2014 of the European Association for the Study of Liver Diseases (EASL)
- Place of Presentation
  London (UK)
- Year and Date
  2014-04-10
- Data Source
  KAKENHI-PROJECT-23249043
[Presentation] Hepatic fibrosis and apoptosis　induced by ethanol administration are exacerbated in human neutrophil peptide－1 transgenic mice2014
- Author(s)
  Rie Ibusuki, Hirofumi Uto, Masaya Kozono, Kohei Oda, Akihiko Ohshige, Kotaro Kumagai, Seiichi Mawatari, Tsutomu Tamai, Akihiro Moriuchi, Makoto Oketani, Akio Ido, HirohitoTsubouchi.
- Organizer
  European Association for the Study of the Liver (EASL)
- Place of Presentation
  London, UK
- Data Source
  KAKENHI-PROJECT-23249043
[Presentation] ヒト好中球ペプチド-1はアルコール性肝障害モデルマウスの肝線維化を促進する2013
- Author(s)
  指宿りえ、宇都浩文、有馬志穂、馬渡誠一、小田耕平、大重彰彦、熊谷公太郎、玉井努、森内昭博、桶谷眞、井戸章雄、坪内博仁
- Organizer
  日本肝臓学会西部会
- Place of Presentation
  岐阜市
- Data Source
  KAKENHI-PROJECT-23249043
[Presentation] The association between serum levels of apoptosis inhibitor of macrophage and the clinical features of nonalcoholic fatty liver disease2013
- Author(s)
  Oda K, Uto H, Mawatari S, Tabu K, Ohno K, Toyokura E, Oshige A, Imanaka D, Kumagai K, Tamai T, Moriuchi A, Oketani M, Ido A, Sumida Y, Tsubouchi H
- Organizer
  The 64th annual meeting of the American Association for the Study of Liver Diseases (AASLD)
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-23249043
[Presentation] Microenvironment in the repair process of injured livers accelerates development of hepatocellular carcinoma2013
- Author(s)
  Tabu, K, Ido A, Kumagai K, Oda Kohei, Mawatari S, Tamai T, Moriuchi A, Uto H, Oketani M, Tsubouchi H
- Organizer
  第19回 Charles Heidelberger 国際がん研究シンポジウム
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] Microenvironment in the repair process of injured livers accelerates development of hepatocellular carcinomaliver cancer nodules.2013
- Author(s)
  Kazuaki Tabu, Akio Ido, Kotaro Kumagai, Kohei Oda, Seiichi Mawatari, Tsutomu Tamai, Akihiro Moriuchi, Hirofumi Uto, Makoto Oketani, and Hirohito Tsubouchi
- Organizer
  第19回Charles Heidelberger国際がん研究シンポジウム
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] 障害肝の修復期に浸潤するマクロファージは間葉系細胞の組織再構築に関与する2012
- Author(s)
  熊谷公太郎、井戸章雄、椨一晃、大野香織、小田耕平、大重彰彦、今中大、馬渡誠一、玉井努、森内昭博、宇都浩文、桶谷眞、坪内博仁
- Organizer
  第49回日本消化器免疫学会総会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] Hepatitis C virus NS3/4A protease inhibits complement activation through cleavage of complement component C42012
- Author(s)
  Mawatari S, Uto H, Kumagai K, Oda K, Tabu K, Ohno K, Oshige A, Imanaka D, Tamai T, Moriuchi A, Oketani M, Ido A, Tsubouchi H, Sato Y, Suzuki T
- Organizer
  The 63th annual meeting of the AASLD
- Place of Presentation
  Boston(USA)
- Year and Date
  2012-11-11
- Data Source
  KAKENHI-PROJECT-23249043
[Presentation] 障害肝の修復期に浸潤するマクロファージは間葉系細胞の組織再構築に関与する2012
- Author(s)
  熊谷公太郎, 井戸章雄, 椨一晃, 大野香織, 小田耕平, 大重彰彦, 今中大, 馬渡誠一, 玉井努, 森内昭博, 宇都浩文, 桶谷眞, 坪内博仁
- Organizer
  第49回日本消化器免疫学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] 肝障害の修復期に浸潤する肝マクロファージの欠損は肝障害を遷延化させる2012
- Author(s)
  熊谷公太郎、井戸章雄、椨一晃、大野香織、小田耕平、最勝寺晶子、今中大、馬渡誠一、呉建、玉井努、森内昭博、宇都浩文、桶谷眞、坪内博仁
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] 肝障害の修復期に浸潤する肝マクロファージの欠損は肝障害を遷延化させる2012
- Author(s)
  熊谷公太郎, 井戸章雄, 椨一晃, 大野香織, 小田耕平, 最勝寺晶子, 今中大, 馬渡誠一, 呉建, 玉井努, 森内昭博, 宇都浩文, 桶谷眞, 坪内博仁
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] Serum levels of apoptosis inhibitor of macrophage (AIM) are associated with hepatic fibrosis and insulin resistance in patients with hepatitis C virus-associated liver disease2012
- Author(s)
  Mera K, Uto H, Sato Y, Yoshimine Y, Oda K, Imanaka D, Saishoji A, Tamai T, Nosaki T, Moriuchi A, Oketani M, Ido A, Tsubouchi H
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Sandiego (USA)
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23249043
[Presentation] Human neutrophil peptide-1 aggravates hepatic fibrosis in a nonalcoholic steatohepatitis mouse model2011
- Author(s)
  Ibusuki R, Uto H, Arima S, Mawatari S, Iwashita Y, Hashimoto S, Maeda T, Tamai T, Moriuchi A, Setoguchi Y, Oketani M, Ido A, Tsubouchi H
- Organizer
  The 62th annual meeting of the AASLD
- Place of Presentation
  San Francisco (USA)
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23249043
[Presentation] 肝炎進展に伴い発現するオステオアクチビンは肝マクロファージの貪食に関与する2011
- Author(s)
  熊谷公太郎, 井戸章雄, 呉建, 椨一晃, 大野香織, 小田耕平, 最勝寺晶子, 今中大, 馬渡誠一, 玉井努, 森内昭博, 宇都浩文, 桶谷眞, 坪内博仁
- Organizer
  第15回 JDDW2011
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] 障害肝において発現するオステオアクチビンは肝マクロファージの貪食に関与する2011
- Author(s)
  熊谷公太郎, 井戸章雄, 呉建, 椨一晃, 大野香織, 小田耕平, 最勝寺晶子, 今中大, 馬渡誠一, 玉井努, 森内昭博, 宇都浩文, 桶谷眞, 坪内博仁
- Organizer
  第48回日本消化器免疫学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] 肝炎の進展過程における炎症の調節因子オステオアクチビンの役割2011
- Author(s)
  熊谷公太郎, 井戸章雄, 呉建, 高見陽一郎, 佐々木文郷, 小田耕平, 最勝寺晶子, 橋口正史, 馬渡誠一, 玉井努, 森内昭博, 宇都浩文, 桶谷眞, 坪内博仁
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590742
[Presentation] Clinical significance of alanine aminotransferase levels and effect of ursodeoxycholic acid in hemodialysis patients with Chronic Hepatitis C2009
- Author(s)
  Nishida C, Uto H, Tokunaga K, Fukumoto M, Sogabe A, Nosaki T, Moriuchi A, Oketani M, Ido A, Tsubouchi H
- Organizer
  19^<th> Conference of the Asian Pacific Association for the Study of the Liver(APASL 2009)
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] Clinical Significance of Alanine Aminotransferase Livels and Effect of Ursodeoxycholic Acid in Hemodialysis Patients with Chronic Hepatitis c.2009
- Author(s)
  Nishida C, Uto H, Tokunaga K, Fukumoto M, Sogabe A, Nosaki T, Moriuchi A, Oketani M, Ido A, Tsubouchi H
- Organizer
  19th Conference of the Asian Pacific Association for the Study of the Liver
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-19209028
[Presentation] Clinical features of p atients aged 75 years or older with chronic hepatitis C and hepatocellular carcinoma in Japanese areas hyperendemic for hepatitis C infection2009
- Author(s)
  Kumagai K, Uto H, Kure T, Mawatari S, Tamai T, Moriuchi A, Hasegawa S, Oketani M, Ido A, Nagata K, Hayashi K, Stuver S, Tsubouchi H
- Organizer
  19^<th> Conference of the Asian Pacific Association for the Study of the Liver(APASL 2009)
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] A fragment of high molecular weight kininogen is upregulated in patients with non-alcoholic fatty liver diserse2008
- Author(s)
  Uto H, Sato Y, Tanoue S, Ishida Y, Tamai T, Hasegawa S, Oketani M, Ido A, Nakajima T, Okanoue T, Tsubouchi H
- Organizer
  59th Annual Meeting of American Association for the Study of Live Diseas
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-19209028
[Presentation] 組換えヒト肝細胞増殖因子を投与した劇症肝炎, 遅発性肝不全の4例2008
- Author(s)
  井戸章雄
- Organizer
  第44回日本腹部救急医学会総会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] Double balloon endoscopic characterization in the small bowel of patients with portal hypertensive enteropathy2007
- Author(s)
  Kodama M, Uto H, Numata M, Hori T, Murayawa T, Tsubocuhi N, Sasaki F, Fujita H, Tahara Y, Ido A, Tsubouchi H
- Organizer
  The 58th Annual Meeting of the American Association for the Study of the Live Disease(AASLD)
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] Proteomic analysis of serum biomarkers in patients with nonalcoholic steatohepatitis using SEDI-TOF/MS or MALDI-TOF/MS2007
- Author(s)
  Uto H, Sato Y, Ishida Y, Takami Y, Kanmura S, Moriuchi A, Hasegawa S, Oketani M, Ido A, Nakajima T, Okanoue T, Tsubouchi H
- Organizer
  The 58th Annual Meeting of the American Association for the Study of the Live Disease(AASLD)
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] 網羅的遺伝子発現解析を用いたHGFの抗アポトーシス機構の解明2007
- Author(s)
  森内昭博, 井戸章雄, 山路尚久, 瀬戸山仁, 重信秀峰, 小原一憲, 沼田政嗣, 長谷川将, 宇都浩文, 宇都浩文, 桶谷真, 坪内博仁
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] 網羅的遺伝子発現解析を用いたHGFの抗アポトーシス機構の解明2007
- Author(s)
  森内昭博、井戸章雄、他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19209028
[Presentation] Evaluation of a rapid semi-quantitative immunochromatographic assay for serum hepatocyte growth factor as a marker in acute hepatic failure : Results from prospective study2007
- Author(s)
  Uto H, Ido A, Moriuchi A, Kumagai K, Shigenobu S, Hasegawa S, Oketani M, Nagoshi S, Mochida S, Tsubouchi H
- Organizer
  6th JSH Single Topic Conference
- Place of Presentation
  安比市
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] Differental acetaminophen-induced hepatotoxicity between two types of dietary steatosis of the liver in mice2007
- Author(s)
  Wang Y, Oketani M, Horiuchi M, Imamura Y, Moriuchi A, Hasegawa S, Uto H, Ido A, Tsubouchi H
- Organizer
  The 58th Annual Meeting of the American Association for the Study of the Live Disease(AASLD)
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] A case of prolonged hepatitis E in Kagoshima2007
- Author(s)
  Moriuchi A, Oda K, Yamashita T, Furuzono M, Hasegawa S, Oketani M, Ido A, Fujisaki K, Tsubouchi H
- Organizer
  6th JSH Single Topic Conference
- Place of Presentation
  安比市
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] コリン欠乏アミノ酸置換食飼育ラットの肝線維化に対してオステオアクチビン強発現が及ぼす影響の解析2007
- Author(s)
  安倍弘生, 蓮池悟, 黒木穣二, 楠元寿典, 児玉眞由美, 永田賢治, 高濱由香, 高見陽一郎, 井戸章雄, 宇都浩文, 坪内博仁
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] Trasnlational research of HGF: A phaseI/IIstudy of recombinant human HGF for the treatment of fulminant hepatic failure2007
- Author(s)
  Ido A, Moriuchi A, Marusawa H, Ikeda K, Numata M, Yamaji N, Setoyama H, Ida H, Oketani M, Chiba T, Tsubouchi H
- Organizer
  6th JSH Single Topic Conferens "Liver Failure:Recent Progress from Pathogenesis to Management"
- Place of Presentation
  安比市
- Data Source
  KAKENHI-PROJECT-19209028
[Presentation] 炎症性腸疾患における組換えヒト肝細胞増殖因子(HGF)注腸治療の検討.ポスター2007
- Author(s)
  瀬戸山仁, 井戸章雄, 沼田政嗣, 山路尚久, 森内昭博, 藤田浩, 宇都浩文, 桶谷真, 坪内博仁
- Organizer
  第49回日本消化器病学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590763
[Presentation] Proteomic analysis of serum biomarkers in patients with nonalcoholic steatohepatitis using SEDI-TOF/MS or MALDI-TOF/MS2007
- Author(s)
  Uto H, Sato Y, Ishida Y, Takami Y, Kanmura S, Moriuchi A, Hasegawa S, Oketani M, Ido A, Nakajima T, Okanoue T, Tsubouchi H
- Organizer
  The 58th Annual Meeting of the American Association for the Study of the Live Disease
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-19209028
[Presentation] 胃酸分泌抑制剤が睡眠時ブラキシズムに与える影響
- Author(s)
  橋本恭子，大牟禮治人，永山邦宏，沼田政嗣，井戸章雄，宮脇正一
- Organizer
  第73回日本矯正歯科学会大会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Year and Date
  2014-10-20 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-24390464

1. MIYAWAKI Shouichi (80295807)

# of Collaborated Projects: 11 results

# of Collaborated Products: 6 results
2. KANMURA Shuji (60448561)

# of Collaborated Projects: 11 results

# of Collaborated Products: 8 results
3. MAEDA Aya (10457666)

# of Collaborated Projects: 10 results

# of Collaborated Products: 3 results
4. 大賀泰彦 (40780002)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
5. UTO Hirofumi (20347058)

# of Collaborated Projects: 7 results

# of Collaborated Products: 58 results
6. TSUBOUCHI Hirohito (60145480)

# of Collaborated Projects: 6 results

# of Collaborated Products: 32 results
7. OKETANI Makoto (50274816)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
8. 丸谷佳菜子 (50828192)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. 中川祥子 (60865301)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
10. HORI Takeshi (00281220)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. 福嶋美佳 (30828190)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
12. MORIUCHI Akihiro (40359823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
13. OHMURE Haruhito (00404484)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. YAGI Takakazu (10346166)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. UEDA Hirotaka (10583445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. NAGAYAMA Kunihiro (60583458)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
17. 渡邉温子 (30883144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 菅真有 (50779973)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 古川みなみ (00806474)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
20. 大迫佑季 (30896999)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
21. 高橋広太郎 (50896983)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. TAKAMI Youichiro (10500473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
23. TAMAI Tsutomu (10343336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
24. KUMAGAI Koutarou (80626664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
25. UEHARA Sawako (50706257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SAKIYAMA Toshio (70542421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. IBUSUKI RIE (90747015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 弘野修一 (00181222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 國則貴玄 (00626666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 池森宇泰 (10755234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 迫口陽子 (70754919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 嶽崎俊郎 (50227013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 後藤雄一 (00637902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 盛真一郎 (00620519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 喜多芳昭 (30570692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 杉浦剛 (40322292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 佐々木文郷 (40735297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 田辺寛 (40814306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 夏越祥次 (70237577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 比地岡浩志 (70305150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 原英二 (80263268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 大塚隆生 (20372766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 松尾美樹 (20527048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 小松澤均 (90253088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 中田匡宣 (90444497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 小田耕平 (80795336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 日野沙耶佳 (20976493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. TABU Kazuaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
49. 桶谷真

# of Collaborated Projects: 0 results

# of Collaborated Products: 51 results
50. 橋口照人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 清水章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IDO Akio 井戸 章雄

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The effects of small intestinal dysbiosis on hepatic steatosis and fibrosisPrincipal Investigator

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Metabolic switch of macrophages infiltrating injured liver, which regulates fibrosis and fibrolysis.Principal Investigator

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Effect of Gpnmb expressed in macrophages on repair of injured liver and hepatocarcinogenesisPrincipal Investigator

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IDO Akio 井戸章雄