Okuda Tsukasa 奥田司

… Alternative Names

OKUDA Tsukasa 奥田司

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Researcher Number	30291587
Other IDs
External Links
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
Affiliation (based on the past Project Information) *help	2023: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授 2011 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2015: 京都府立医科大学, 医学研究科, 教授 2009 – 2012: Kyoto Prefectural University of Medicine, 医学研究科, 教授 2006 – 2008: Kyoto Pref Univ Med, Graduate Scool of Medicine, Associate Prof, 医学研究科, 准教授 … More 2007: Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Professor 2004 – 2005: Kyoto prefectural University of Medicine, Department of Digestive Surgery, Subprofessor, 医学研究科, 助教授 2003: Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Department of Molecular-Targeting Cancer Prevention, Assistant Professor (Kohshi), 医学研究科, 講師 1997 – 2002: 京都府立医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Hematology / Biological Sciences / Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Digestive surgery / Hematology / Basic Section 52050:Embryonic medicine and pediatrics-related / Hematology / General medical chemistry / Digestive surgery / Basic Section 54010:Hematology and medical oncology-related / Pediatrics / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator AML1 / 転写因子 / 白血病 / RUNX1 / ES細胞 / 造血幹細胞 / 遺伝子改変マウス / PEBP2 / 染色体転座 / leukemia … More / 翻訳後修飾 / 造血 / RUNX / ETO / AML1-MTG8 / 遺伝子ターゲティング / がん遺伝子 / hematopoiesis / Runx1 / 造血発生 / Yeast Two-Hybrid / TRAIL / CBFA1 / runt / transcription factor / gene targeting / oncogene / transcription / リンパ球 / リン酸化 / T細胞 / 骨髄異形成症候群 / 胸腺 / 胚幹(ES)細胞 / クロマチンリモデリング / キナーゼ / Yeast two-hybrid / Yeast two hybrid / C11orf21 / 転写調節 / 分子標的薬 / 転写制御 / 造血器腫瘍 / 転写コファクター / CBFB / 分子標的 / 造血器疾患 / retrovirus / genome-modified mouse / cancer / レトロウイルス / 癌 / Gene-Targeting / Transcription Factor / Leukemia / Hematopoiesis / Runx3 / Runx / knock-in mouse / T-lymphocyte / myelodysplastic syndrome / thymus / embronic stem (ES) cell / chromosome translocation / embryonic stem (ES) cell / embryonic stem(ES) cell / ノックイン / マウスモデル / 蛋白間相互作用 / 造血制御 / 血液腫瘍学 / 遺伝子変異マウス / 骨髄異型性症候群 / 急性骨髄性白血病 / 挿入型遺伝子変異 / 成体型造血 / 胚型造血 … More Except Principal Investigator RUNX3 / 胃癌 / 遺伝子診断 / 癌抑制遺伝子 / RUNX1 / 転写因子 / Runx1 / 造血幹細胞 / ラブドイド腫瘍 / SWI/SNF複合体 / Gastric cancer / diagnosis / FISH / 転写制御 / SNF5 / GFP / 蛍光in situ分子雑種法 / 染色体転座 / Bim / MALT1 gene / oncogene / lymphoma / 骨髄異形成症候群 / tandem duplication / 急性骨髄性白血病 / チロシンキナーゼ / IL-3 / c-kit / IL-6 / gp130 / 発癌予防 / TRKA / 遺伝子発現 / プロモーター / 遺伝子発現制御 / スーパーエンハンサー / RIUNX1 / 造血 / 白血病 / SWI/SNF / RUNX / クロマチンリモデリング因子 / Rhabdoid腫瘍 / クロマチン免疫沈降法 / 悪性ラブドイド腫瘍 / 標的遺伝子 / Suppressor gene / transgenic mouse / alpha2A adrenoceptor / トランスジェニックマウス / α2Aアドレナリン受容体 / 遺伝子改変マウス / α2アドレナリン受容体 / Tumor suppressor gene / Molecular diagnosis / Chromosomal deletion / Chromosomal translocation / Acute myeloblastic leukemia / Myelodysplastic syndrome / Fluorescence in situ hybridization / Spectral karyotypinig / 染色体欠失 / FISH法 / SKY法 / chromosome / IGH gene / conogene / myeloma / 多発性骨髄種 / がん遺伝子 / 免疫グロブリンH鎖遺伝子 / 多発性骨髄腫 / 蛍光in Site分子雑種法 / AML2 (RUNX3) / AML2 / mTOR / PI3-K / Ras / BH3-onIy death activators / Dynein light chain / Apoptosis / Hematopoietic progenitors / 欠損マウス / LC8 / ダイニン / アポトーシス / 造血細胞 / サイトカイン / lgH / MALTI gene / IgH gene / myelodysplastic syndrome / acute myelogenous leukemia / mutation / tyrosine kinase / FLT3 gene / MDS / FLT3 / 遺伝子変異 / チロシソキナーゼ / FLT3遺伝子 / transcription factor / hematopoietic stem cell / crosstalk / hematopoietic signal / アンチセンスDNA / クロストーク / 造血シグナル / ノンコーディングRNA / 分子生物学 / 血球産生型血管内皮 / 胃十二指腸外科 Less

Functional analysis of transcription factors and novel SWI/SNF complexes in the tumorigenesis of rhabdoid tumors.
- Principal Investigator
  
  桑原康通
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.Principal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of the molecular mechanisms of malignant rhabdoid tumors mediated by dysregulation of super-enhancer function.
- Principal Investigator
  
  Kuwahara Yasumichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of cell differentiation by hematopoietic transcription factor RUNX1 and translation to a novel molecular target strategy
- Principal Investigator
  
  TADAGAKI Kenjiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Search for novel intervention methods for hematopoietic transcription control and research for its clinical applicationPrincipal Investigator
- Principal Investigator
  
  Okuda Tsukasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of hematopoietic regulation mechanisms by a novel repressor for RUNX1
- Principal Investigator
  
  YOSHIDA TATSUSHI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Regulation mechanisms of hematopoietic transcription factor RUNX1 through the transcription network analyses
- Principal Investigator
  
  TADAGAKI KENJIRO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
The clarification of a tumorigenesis of malignant rhabdoid tumor through a understanding of control mechanism of RUNX1 by hSNF5
- Principal Investigator
  
  Kuwahara Yasumichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Nalysis of novel tumor suppressor gene RUNX3 of gastric cancer and clinical application for the diagnosis and prevention of gastric cancer
- Principal Investigator
  
  Sakakura Chouhei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
RUNX1 as a molecular target for a novel hematopoietic reguationPrincipal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Runx1による造血幹細胞産生メカニズムの解明
- Principal Investigator
  
  山元康敏
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of novel gastric tumor suppressor RUNX3 for the clinical application of gastric cancer treatment
- Principal Investigator
  
  sakakura chouhei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Regulatory mechanisms of the leukemia-associated transcription factor, RUNX1/AML1, through the post-translational modifications.Principal Investigator
- Principal Investigator
  
  TSUKASA Okuda
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Does Runx1 produce hematopoietic stem cell from hemogenic endothelium via Endothelial to Mesenchymal Transition?
- Principal Investigator
  
  YAMAMOTO Yasutoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of novel tumor suppressor gene RUNX3 of gastric cancer and clinical application for the diagnosis and prevention of gastric cancer
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Transcriptional Dysregulation in Abnormal Hematopoiesis and LeukemiaPrincipal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular analysis of novel tumor suppressor RUNX3 in gastric cancers and its clinical application
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
胃癌新規癌抑制遺伝子RUNX3の異常を伴う胃癌前駆細胞の同定と遺伝子診断への応用
- Principal Investigator
  
  阪倉長平
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Leukemogenic Mechanism by genomic mutations of hematopoietic-speci is transcription factor, AML1/RUNX1Principal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of novel tumor suppressor gene RUNX3 in gastric cancer
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto prefectural University of Medicine
胃癌新規癌抑制遺伝子RUNX3の異常を伴う胃癌前駆細胞の同定と遺伝子診断への応用
- Principal Investigator
  
  阪倉長平
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular analysis for hematopoietic regulation by transcription factor, AML1/Runxl.Principal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine Graduate School of Medical Science
AML1/RUNX1遺伝子の微細変異による造血器腫瘍発症メカニズムの検討Principal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
Application of RUNX3 in the diagnosis and treatment of gastric cancer
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto prefectural University of Medicine
Making a transgenic mouse with α 2A adrenoceptor fused with GFP
- Principal Investigator
  
  MIZOBE Toshiki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyoto Prefectural University of Medicine
白血病・骨髄異形成症候群発症におけるAML1遺伝子変異の生物学的意義Principal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
新しい胃癌の癌抑制遺伝子RUNX3の解析と遺伝子診断への応用
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular dissection of the leukemia-associated transcription factor, AML1/RUNX1,in hematopoietic regulationPrincipal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
IDENTIFICATION OF CHROMOSOMAL REARRANGEMENTS SPECIFIC TO MYELODYSPLASTIC SYNDROME USING MULTICOLOR SPECTRAL KARYOTYPING
- Principal Investigator
  
  TANIWAKI Masafumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
白血病発症におけるAML1遺伝子変異の生物学的意義に関する研究Principal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
転写因子AML1/PEBP2αBによる造血初期発生制御機構Principal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
AML1(PEBP2αB)遺伝子の融合型変異たよる白血病発症メカニズムの研究Principal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
Functional analysis of the Bim/DLC complex in apoptosis regulation of hematopoietic progenitors
- Principal Investigator
  
  INABA Toshiya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  HIROSHIMA UNIVERSITY
  Jichi Medical University
Analysis of novel tumor suppressor gene AML2 in gastric cancer
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto prefectural University of Medicine
Molecular basis for leukemic transformation caused by chimeric protein involving the transcription factor AML1 (PEBP2aB).Principal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
SUBCLASSFICIATION OF MULTIPLE MYELOMA BASED ON THE PARTNER GENES OF TUMOR-SPECIFIC IMMUNOGLOBULIN HEAVY CHAIN GENE TRANSLOCATION BY USING DOUBLE-COLOR FLUORESCENCE IN SITU HYBRIDIZATION
- Principal Investigator
  
  TANIWAKI Masafumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
Biologic characterization of leukemia-associated transcription factor AML1 (PEBP2αB) in hematopoiesisPrincipal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Prefectural University of Medicine
AML1/PEBP2αBプロトオンコジーンによる造血制御の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Prefectural University of Medicine
FLT3 gene
- Principal Investigator
  
  YOKOTA Shohei
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular mechanism of hematopoietic regulation by leukemia-related transcription factor AML1(PEBP2αB)Principal Investigator
- Principal Investigator
  
  OKUDA Tsukasa
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
INTERPHASE DETECTION OF GENE REARRANGEMENTS SPECIFIC TO NON-HODGKIN'S LYMPHOMA USING DOUBLE-COLOR FISH
- Principal Investigator
  
  TANIWAKI Masafumi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
AML1/PEBP2αBプロトオンコジーンによる造血制御の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  奥田司
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of crosstalks between hematopoietic signals and their molecular mechanisms
- Principal Investigator
  
  SONODA Yoshiaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] t(8;21)とAML1/RUNX1：日本臨床74巻　増刊号８2016
- Author(s)
  奥田　司
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15K09487
[Book] inv（16）とCBFB-MYH11：日本臨床74巻　増刊号８2016
- Author(s)
  奥田　司
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15K09487
[Book] AML1/RUNX1転座と白血病.（第4章B-1）造血器腫瘍アトラス改訂第5版（谷脇雅史・横田昇平・黒田純也・編）2016
- Author(s)
  奥田　司
- Publisher
  日本醫事新報社（東京）
- Data Source
  KAKENHI-PROJECT-15K09487
[Book] 造血器腫瘍アトラス(第4版)第5章a)i)「AML1/RUNX1」
- Author(s)
  奥田司
- Publisher
  日本医事新報社(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591078
[Journal Article] Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors2023
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 15 Pages: 16323-16336
- DOI
  10.1002/cam4.6255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07941, KAKENHI-PROJECT-22K08483
[Journal Article] クロマチンリモデリング機構アップデートと創薬2023
- Author(s)
  桒原康通、奥田　司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 132 Pages: 85-99
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08483
[Journal Article] 細胞死シグナルの最新理解とがんの分子標的薬2023
- Author(s)
  吉田達士、奥田　司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 132 Pages: 101-118
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08483
[Journal Article] C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO2022
- Author(s)
  Matsumoto Akifumi、Yoshida Tatsushi、Shima Takahiro、Yamasaki Kenta、Tadagaki Kenjiro、Kondo Noriko、Kuwahara Yasumichi、Zhang Dong-Er、Okuda Tsukasa
- Journal Title
  
  BBA Advances
  
  Volume: 2 Pages: 100047-100047
- DOI
  10.1016/j.bbadva.2022.100047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846
[Journal Article] TRAIL創薬2022
- Author(s)
  吉田達士、酒井敏行、奥田　司
- Journal Title
  
  医学のあゆみ
  
  Volume: 283
- Data Source
  KAKENHI-PROJECT-22K08483
[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand is a novel transcriptional target of runt-related transcription factor 12022
- Author(s)
  Yoshida Tatsushi、Yamasaki Kenta、Tadagaki Kenjiro、Kuwahara Yasumichi、Matsumoto Akifumi、Sofovic Adem、Kondo Noriko、Sakai Toshiyuki、Okuda Tsukasa
- Journal Title
  
  International Journal of Oncology
  
  Volume: 60 Issue: 1 Pages: 1-1
- DOI
  10.3892/ijo.2021.5296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors2022
- Author(s)
  Shinohara Haruka、Sawado Rie、Nakagawa Makoto、Hattori Ayuna、Yamagata Kazutsune、Tauchi Kimiharu、Ito Jumpei、Kuwahara Yasumichi、Okuda Tsukasa、Ogawa Chitose、Kitabayashi Issay
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 27 Pages: 14-25
- DOI
  10.1016/j.omto.2022.09.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08483
[Journal Article] Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia2020
- Author(s)
  Matsumura Takayoshi、Nakamura-Ishizu Ayako、Muddineni Siva Sai Naga Anurag、Tan Darren Qiancheng、Wang Chelsia Qiuxia、Tokunaga Kenji、Tirado-Magallanes Roberto、Sian Stephanie、Benoukraf Touati、Okuda Tsukasa、Asou Norio、Matsuoka Masao、Osato Motomi、Suda Toshio
- Journal Title
  
  Blood
  
  Volume: 136 Issue: 17 Pages: 1919-1932
- DOI
  10.1182/blood.2019004292
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K08846, KAKENHI-PROJECT-18H05284
[Journal Article] Novel Two MRT Cell Lines Established from Multiple Sites of a Synchronous MRT Patient2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara, Eisuke Ichise, Yoshiki Katsumi, Kazutaka Ouchi, Kunihiko Tsuchiya, Mitsuru Miyachi, Eiichi Konishi, Hiroyasu Sasajima, Satoaki Nakamura, Shigehisa Fumino, Tatsuro Tajiri, Pascal D Johann, Michael Fruhwald, Tsukasa Okuda, Hajime Hosoi
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 11 Pages: 6159-6170
- DOI
  10.21873/anticanres.14636
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08257, KAKENHI-PROJECT-19K08846, KAKENHI-PROJECT-19K09053, KAKENHI-PROJECT-19H03719
[Journal Article] 細胞死とがん2019
- Author(s)
  吉田達士，山崎健太，奥田司
- Journal Title
  
  Journal of Kyoto Prefectural University of Medicine
  
  Volume: 128 Issue: 2 Pages: 81-99
- DOI
  10.32206/jkpum.128.02.081
- ISSN
  0023-6012
- Year and Date
  2019-02-25
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-17K09936
[Journal Article] Molecular heterogeneity in APIP-FGFR2 fusion transcripts with diversity of genomic breakpoints in gastric cancer high-level amplifications at 11p13 and 10q262017
- Author(s)
  Okuda T, Taki T, Nishida K Chinen Y, Nagoashi H, Sakakura C, Ohtsuji E, Taniwaki M
- Journal Title
  
  Oncol Lett
  
  Volume: 13 Issue: 1 Pages: 215-221
- DOI
  10.3892/ol.2016.5386
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09486, KAKENHI-PROJECT-16K09856, KAKENHI-PROJECT-16K10512
[Journal Article] Loss of RUNX1/AML1 arginine-methylation impairs peripheral T cell homeostasis.2015
- Author(s)
  Mizutani S, Yoshida T, Zhao X, Nimer SD, Taniwaki M, and Okuda T.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591408
[Journal Article] クロマチンリモデリングの異常と腫瘍発生2015
- Author(s)
  桒原康通，細井創，奥田司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 124 Pages: 825-838
- Open Access
- Data Source
  KAKENHI-PROJECT-15K09487
[Journal Article] MAZR and Runx factors synergistically repress ThPOK during CD8+ T cell lineage development.2015
- Author(s)
  Sakaguchi S, Hainberger D, Tizian C, Tanaka H, Okuda T, Taniuchi I, Ellmeier W
- Journal Title
  
  Journal of Immunology
  
  Volume: 195 Issue: 6 Pages: 2879-2887
- DOI
  10.4049/jimmunol.1500387
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09487, KAKENHI-PUBLICLY-26114720, KAKENHI-PROJECT-26293109
[Journal Article] Interaction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27.2015
- Author(s)
  Hino H, Dai P, Yoshida T, Hatakeyama T, Harada Y, Otsuji E, Okuda T, Takamatsu T
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 1-11
- DOI
  10.1038/srep15365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09487
[Journal Article] 造血の転写制御と白血病2015
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、奥田司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 124 Pages: 797-812
- Open Access
- Data Source
  KAKENHI-PROJECT-15K09487
[Journal Article] Loss of RUNX1/AML1 arginine-methylation impairs in peripheral T cell homeostasis.2015
- Author(s)
  Mizutani S, Yoshida T, Zhao X, Nimer SD, Taniwaki M, Okuda T
- Journal Title
  
  British Journal of Haematology
  
  Volume: 170 Issue: 6 Pages: 859-873
- DOI
  10.1111/bjh.13499
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09487
[Journal Article] 血管内皮細胞による造血幹細胞の維持2014
- Author(s)
  山元康敏、奥田　司
- Journal Title
  
  血液内科
  
  Volume: 69 Pages: 309-320
- Data Source
  KAKENHI-PROJECT-26460375
[Journal Article] 血管内皮細胞による造血幹細胞の維持.2014
- Author(s)
  山元康敏、奥田　司
- Journal Title
  
  血液内科
  
  Volume: 69 Pages: 309-320
- Data Source
  KAKENHI-PROJECT-24591408
[Journal Article] 血球発生と血管分化のcrossroad2013
- Author(s)
  山元康敏、奥田　司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 122 Pages: 329-340
- Data Source
  KAKENHI-PROJECT-24591408
[Journal Article] <特集「個体発生と細胞分化の医学」>血球発生と血管分化のCrossroad2013
- Author(s)
  山元康敏, 奥田司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 122(6) Pages: 329-340
- Data Source
  KAKENHI-PROJECT-23590345
[Journal Article] ＜特集「個体発生と細胞分化の医学」＞血球発生と血管分化のCrossroad.2013
- Author(s)
  山元康敏,　奥田　司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 122（6） Pages: 329-340
- Data Source
  KAKENHI-PROJECT-23590345
[Journal Article] 造血発生制御の今日的理解2010
- Author(s)
  横田明日美, 奥田司
- Journal Title
  
  京都府立医科大学雑誌
  
  Volume: 119 Pages: 681-693
- Data Source
  KAKENHI-PROJECT-21591214
[Journal Article] A 5′untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model2010
- Author(s)
  Nagamachi A, Htun PW, Ma F, Miyazaki K, Yamasaki N, Kanno M, Inaba T, Honda Z, Okuda T, Oda H, Tsuji K, Honda H
- Journal Title
  
  Developmental Biology
  
  Volume: 345 Pages: 226-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591214
[Journal Article] Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development2008
- Author(s)
  Setoguchi R, Tachibana M, Naoe Y, Muroi S, Akiyama K, Tezuka C, Okuda T, Taniuchi I
- Journal Title
  
  Science 319(5864)
  
  Pages: 822-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] AML1/runx1 works as a negative regulator of C-MPL in hematopoietic stem cells2008
- Author(s)
  Satoh Y, Matsumura I, Tanaka H, Ezoe S, Fukushima K, Tokunaga M, Yasumi M, Shibayama H, Mizuki M, Era T, Okuda T, Kanakura Y
- Journal Title
  
  J Biol Chem. 283(44)
  
  Pages: 30045-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] 分子標的研究.2007
- Author(s)
  奥田司
- Journal Title
  
  日本臨床 65・創刊号1
  
  Pages: 128-135
- Data Source
  KAKENHI-PROJECT-18591078
[Journal Article] 急性骨髄性白血病モデルマウスからの治療へのアプローチ.2007
- Author(s)
  奥田司
- Journal Title
  
  血液フロンティア 17・4
  
  Pages: 517-528
- Data Source
  KAKENHI-PROJECT-18591078
[Journal Article] AML1/Runx1による白血病発症機構.2006
- Author(s)
  奥田司
- Journal Title
  
  血液腫瘍科 52・6
  
  Pages: 605-614
- Data Source
  KAKENHI-PROJECT-18591078
[Journal Article] AML1/Runx1による白血病発症機構2006
- Author(s)
  奥田司
- Journal Title
  
  血液腫傷科 52
  
  Pages: 605-614
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591078
[Journal Article] 造血の転写制御と急性骨髄性白血病2005
- Author(s)
  奥田司
- Journal Title
  
  京都府立医科大学雑誌 114・9
  
  Pages: 561-580
- NAID
  110001714982
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590955
[Journal Article] マウスにおける標的遺伝子組み換え実験の新技術.2004
- Author(s)
  奥田司
- Journal Title
  
  細胞 36・11
  
  Pages: 30-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590955
[Journal Article] マウスにおける標的遺伝子組み換え実験の新技術2004
- Author(s)
  奥田司
- Journal Title
  
  細胞 36・11
  
  Pages: 30-34
- Data Source
  KAKENHI-PROJECT-16590955
[Journal Article] RUNXファミリーと白血病2004
- Author(s)
  奥田司
- Journal Title
  
  血液腫瘍科 49・1
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-16590955
[Journal Article] RUNXファミリーと白血病.2004
- Author(s)
  奥田司
- Journal Title
  
  血液腫瘍科 49・1
  
  Pages: 1-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590955
[Journal Article] マウスにおける標的遺伝子組み換え実験の新技術2004
- Author(s)
  奥田司
- Journal Title
  
  細胞 36(11)
  
  Pages: 30-34
- Data Source
  KAKENHI-PROJECT-15390478
[Journal Article] RUNXファミリーと白血病2004
- Author(s)
  奥田司
- Journal Title
  
  血液腫瘍科 49(1)
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-15390478
[Presentation] Transcriptional regulation of G1-cyclin gene CCND1 by RUNX1 and its leukemia-related form RUNX1-ETO.2022
- Author(s)
  Yoshihito Shimizu, Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第45回日本分子生物学会年会（幕張）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] RUNX1/AML1遺伝子の発現を制御する新規転写因子群の探索2022
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、清水義仁、桒原康通、吉田達士、奥田司
- Organizer
  第９５回日本生化学会大会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] TRAIL is a novel target gene of RUNX1/AML1 transcription factor.2022
- Author(s)
  Tatsushi YOSHIDA, Kenta YAMASAKI, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Akifumi MATSUMOTO, Adem Ejub SOFOVIC, Noriko KONDO, Toshiyuki SAKAI, Tsukasa OKUDA
- Organizer
  第84回日本血液学会学術集会　（博多）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] Role of the RUNX family in the NRTK1 gene regulation for neuroblastoma cells.2022
- Author(s)
  Aya Nakae, Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会
- Data Source
  KAKENHI-PROJECT-22K07941
[Presentation] Role of the RUNX family in the NRTK1 gene regulation for neuroblastoma cells.2022
- Author(s)
  Aya Nakae, Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会大会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] RUNX1 requires SNF5 for its functional cooperation with the chromatin remodeling complex, SWI/SNF.2022
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Tsukasa Okuda
- Organizer
  第９５回日本生化学会大会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K08483
[Presentation] A seaweed-derived compound that inhibits growth of acute myeloid leukemia cells.2021
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Yasumichi Kuwahara, Tsukasa Okuda.
- Organizer
  第80回日本癌学会学術総会（横浜）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] A seaweed-derived compound that inhibits growth of acute myeloid leukemia cells.2021
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Yasumichi Kuwahara, Tsukasa Okuda.
- Organizer
  第８０回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] 造血制御転写因子 RUNX1 標的遺伝子の解析2021
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康通、近藤則子、松本晃典、酒井敏行、奥田司
- Organizer
  第１１回４大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Two New MRT Cell Lines Established from Multiple Sites of a Synchronous MRT with a Unique DNA Methylation Pattern.2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara,Yoshiki Katsumi, Kunihiko Tsuchiya　,Mitsuru Miyachi, Tatsuro Tajiri, Tatsushi Yoshida, Tsukasa Okuda, Hajime Hosoi
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08257
[Presentation] クロマチンリモデリング因子研究におけるラブドイド腫瘍細胞株の有用性2020
- Author(s)
  桒原康道、近藤則子、忠垣憲次郎、山崎健太、吉田達士、奥田司
- Organizer
  第２４回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Two New MRT Cell Lines Established from Multiple Sites of a Synchronous MRT with a Unique DNA Methylation Pattern.2020
- Author(s)
  Yasumichi Kuwahara, Tomoko Iehara,Yoshiki Katsumi, Kunihiko Tsuchiya　,Mitsuru Miyachi, Tatsuro Tajiri, Tatsushi Yoshida, Tsukasa Okuda, Hajime Hosoi
- Organizer
  第79回日本癌学会学術総会（広島）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] DNAメチル化プロファイルを用いたラブロイド腫瘍患者の同時多発病変より樹立した新規２細胞株の解析2020
- Author(s)
  桒原康通、家原知子、勝見良樹、土屋邦彦、宮地充、田尻達郎、忠垣憲次郎、吉田達士、奥田司、細井創
- Organizer
  第７９回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] 転写因子RUNX1/AML1の新規候補標的遺伝子群の探索2019
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第９２回日本生化学会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] 転写因子RUNX1/AML1の新規候補標的遺伝子群の探索2019
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第９２回日本生化学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Analysis of a novel transcriptional target gene of RUNX1.2019
- Author(s)
  Tatsushi YOSHIDA, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Toshiyuki SAKAI, and Tsukasa OKUDA
- Organizer
  第78回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] SWI/SNFクロマチンリモデリング因子と造血系転写因子の機能調節2019
- Author(s)
  桒原康道、近藤則子、忠垣憲次郎、山崎健太、吉田達士、奥田司
- Organizer
  第２３回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] 造血関連転写因子 RUNX1による制御遺伝子の探索2019
- Author(s)
  山崎健太、忠垣憲次郎、近藤則子、桑原康通、吉田達士、奥田司
- Organizer
  第42回日本分子生物学会年会（福岡）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] 転写因子RUNX1/AML1の新規候補標的遺伝子群の探索2019
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第92回日本生化学会大会（横浜）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] 造血関連転写因子 RUNX1による制御遺伝子の探索2019
- Author(s)
  山崎健太、忠垣憲次郎、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第４２回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Identification of a novel RUNX1 target by public data re-analysis that is suppressed by RUNX1-ETO.2019
- Author(s)
  Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Donger Zhang, Tsukasa Okuda
- Organizer
  第８１回日本血液学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Identification of a novel RUNX1 target by public data re-analysis that is suppressed by RUNX1-ETO2019
- Author(s)
  Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Donger Zhang, Tsukasa Okuda
- Organizer
  第81回日本血液学会学術集会（東京）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] Analysis of a novel transcriptional target gene of RUNX1.2019
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Yasumichi Kuwahara, Toshiyuki Sakai, Tsukasa Okuda.
- Organizer
  第７８回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Identification of a novel RUNX1 target by public data re-analysis that is suppressed by RUNX1-ETO2019
- Author(s)
  Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Donger Zhang, Tsukasa Okuda
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] Analysis of a novel transcriptional target gene of RUNX1.2019
- Author(s)
  Tatsushi YOSHIDA, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Toshiyuki SAKAI, and Tsukasa OKUDA
- Organizer
  第78回　日本癌学会学術総会（京都）
- Data Source
  KAKENHI-PROJECT-19K08846
[Presentation] 造血関連転写因子 RUNX1による制御遺伝子の探索2019
- Author(s)
  山崎健太、忠垣憲次郎、近藤則子、桑原康通、吉田達士、奥田司
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] 造血関連転写因子RUNX1(AML1)の新規転写標的候補遺伝子の探索2018
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第４１回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] 造血関連転写因子RUNX1(AML1)の新規転写標的候補遺伝子の探索2018
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] Analysis of a novel candidate target gene of the hematopoietic transcription factor RUNX1 (AML1).2018
- Author(s)
  Kenjiro Tadagaki, Kenta Yamasaki, Noriko Kondo, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第８０回日本血液学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Newly established MRT cell lines from multiple sites of a synchronous MRT patient2018
- Author(s)
  Yasumichi Kuwahara, Hajime Hosoi, Tsukasa Okuda
- Organizer
  International Rhabdoid Tumor Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] クロマチンリモデリング因子SNF5と細胞の腫瘍化2018
- Author(s)
  桒原康道、近藤則子、忠垣憲次郎、山崎健太、吉田達士、奥田司
- Organizer
  第２２回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A novel transcription factor RUNX1.2018
- Author(s)
  Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Yasumichi Kuwahara, Noriko Kondo,　Akifumi Matsumoto, Toshiyuki Sakai, Tsukasa Okuda.
- Organizer
  第９１回日本生化学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Functional interaction between SWI/SNF complex and a hematopoietic transcription factor in malignant rhabdoid tumor.2018
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenjiro Tadagaki, Tsukasa Okuda.
- Organizer
  第７７回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Functional interaction between SWI/SNF complex and a hematopoietic transcription factor in malignant rhabdoid tumor.2018
- Author(s)
  Yasumichi KUWAHARA, Tatsushi YOSHIDA, Kenjirou TADAGAKI and Tsukasa OKUDA.
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] Analysis of a novel candidate target gene of the hematopoietic transcription factor RUNX1 (AML1).2018
- Author(s)
  Kenjiro Tadagaki, Kenta Yamasaki, Noriko Kondo, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第80回日本血液学会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] 急性骨髄性白血病におけるRUNX1新規標的遺伝子の同定2018
- Author(s)
  松本晃典、吉田達士、山崎健太、忠垣憲次郎、桒原康道、近藤則子、奥田司
- Organizer
  平成３０年度第８回４大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A novel transcriptional target of RUNX1.2018
- Author(s)
  Tatsushi YOSHIDA, Kenta YAMASAKI, Kenjiro TADAGAKI, Yasumichi KUWAHARA, Noriko KONDO, Akifumi MATSUMOTO, Toshiyuki SAKAI, and Tsukasa OKUDA.
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] Functional interaction between SWI/SNF complex and a hematopoietic transcription factor in malignant rhabdoid tumor.2018
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenjiro Tadagaki　and Tsukasa Okuda
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] An array-based approach for novel RUNX1(AML1)-target genes.2017
- Author(s)
  Kenjiro Tadagaki, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第７６回日本癌学会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] Candidate target genes of hematopoietic transcription factor RUNX1 (AML1).2017
- Author(s)
  Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第79回日本血液学会
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] RUNX1/AML1転写因子の新規候補標的遺伝子の解析2017
- Author(s)
  忠垣憲次郎、山崎健太、桒原康道、吉田達士、奥田司
- Organizer
  第６４回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] RUNX1によるTRAIL遺伝子の転写制御機構2017
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康道、酒井敏行、奥田司
- Organizer
  第21回造血器腫瘍研究会
- Place of Presentation
  熊本大学（熊本市）
- Year and Date
  2017-02-17
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Mechanism of recruitment of SWI/SNF complex via interaction between SNF5 and transcription factor.2017
- Author(s)
  Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda
- Organizer
  2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会/第90回日本生化学会大会)
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] An array-based approach for novel RUNX1(AML1)-target genes.2017
- Author(s)
  Kenjiro Tadagaki, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第７６回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Mechanism of recruitment of SWI/SNF complex via interaction between SNF5 and transcription factor.2017
- Author(s)
  Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda
- Organizer
  2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会/第90回日本生化学会大会)
- Data Source
  KAKENHI-PROJECT-16K10038
[Presentation] Candidate target genes of hematopoietic transcription factor RUNX1 (AML1).2017
- Author(s)
  Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第７９回日本血液学会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] RUNX1/AML1転写因子の新規候補標的遺伝子の解析2017
- Author(s)
  忠垣憲次郎、山崎健太、桒原康道、吉田達士、奥田司
- Organizer
  第６４回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-17K09936
[Presentation] Candidate target genes of hematopoietic transcription factor RUNX1 (AML1).2017
- Author(s)
  Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第７９回日本血液学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] RUNX1/AML1転写因子の新規候補標的遺伝子の解析2017
- Author(s)
  忠垣憲次郎、山崎健太、桒原康通、吉田達士、奥田　司
- Organizer
  第64回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] Mechanism of recruitment of SWI/SNF complex via interaction between SNF5 and transcription factor.2017
- Author(s)
  Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  2017年度生命科学系合同年次大会（第40回日本分子生物学会年会/第90回日本生化学会大会）
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] 白血病由来RUNX1遺伝子変異体における機能的異常の解析2017
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康道、近藤則子、奥田司
- Organizer
  平成２９年度第７回４大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Mechanism of recruitment of SWI/SNF complex via interaction between SNF5 and transcription factor.2017
- Author(s)
  Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] An array-based approach for novel RUNX1(AML1)-target gennes.2017
- Author(s)
  Kenjiro Tadagaki, Yasumichi Kuwahara, Tatsushi Yoshida ,Tsukasa Okuda.
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] Analysis of a transcriptional target gene regulated by RUNX1/AML12016
- Author(s)
  Yoshida T, Kuwahara Y, Sakai T, Okuda T.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] A candidate target gene of RUNX1/AML1 transcription factor.2016
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Toshiyuki Sakai, Tsukasa Okuda.
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A candidate target gene of RUNX1/AML1 transcription factor．2016
- Author(s)
  Yoshida T, Tadagaki K, Yamasaki K, Kuwahara Y, Sakai T, Okuda T.
- Organizer
  第78回日本血液学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] A natural inhibitor of Runt-related Transcription Factor 1 / Acute Myeloid Leukemia 1 (RUNX1/AML1).2016
- Author(s)
  Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Yasumichi Kuwahara, Tsukasa Okuda.
- Organizer
  第89回日本生化学会
- Place of Presentation
  東北大学（仙台市）
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] RUNX1/AML1はTRAILの転写制御に関与する2016
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康通、酒井敏行、奥田司
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A natural inhibitor of Runt-related Transcription Factor 1 / Acute Myeloid Leukemia 1 (RUNX1/AML1).2016
- Author(s)
  Yoshida T, Yamasaki K, Tadagaki K, Kuwahara Y, Okuda T.
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] 白血病関連転写因子の制御法の開発と白血病治療に向けた応用2016
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康道、奥田司
- Organizer
  平成28年度第6回4大学連携研究フォーラム
- Place of Presentation
  京都薬科大学（京都市）
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] RUNX1/AML1はTRAILの転写制御に関与する2016
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康道、酒井敏行、奥田司
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] AML1/RUNX1機能制御因子の探索．2016
- Author(s)
  吉田達士、中村加世子、水谷信介、奥田　司
- Organizer
  第20回造血器腫瘍研究会
- Place of Presentation
  木更津
- Year and Date
  2016-02-12
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] Runx1/AML1のアルギニンメチル化による末梢T細胞恒常性の制御．2015
- Author(s)
  水谷信介、吉田達士、谷脇雅史、奥田　司
- Organizer
  第38回日本分子生物学会年会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] Elucidation of the repression mechanism in AML1/Runx1 transcriptional activity by CRP12015
- Author(s)
  Yoshida T, Okuda T
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] A functional repressor for Runt-related transcription factor 1/Acute Myeloid Leukemia 1.2015
- Author(s)
  Yoshida T, Nakamura K , Mizutani S, and Okuda T.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-18
- Data Source
  KAKENHI-PROJECT-15K09487
[Presentation] AML1/Runx1機能制御に関わる新規共役因子の解析.2014
- Author(s)
  吉田達士, 中村加世子, 水谷信介, 奥田　司.
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-24591408
[Presentation] A candidate co-factor which regulates acute myeloid leukemia 1/runt-related transcription factor 1 (AML1/Runx1) function.2014
- Author(s)
  Yoshida T, and Okuda T.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24591408
[Presentation] AML1アルギニンメチル化の喪失は末梢T細胞集団の不均衡を惹起する2013
- Author(s)
  水谷信介、谷脇雅史、奥田　司
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24591408
[Presentation] 間葉細胞/血管内皮分化過程を解析可能な新規細胞培養システムの構築2013
- Author(s)
  山元康敏, Lawrence S. Prince, 奥田　司
- Organizer
  第３回　4大学連携研究フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590345
[Presentation] 間葉細胞/血管内皮分化過程を解析可能な新規細胞培養システムの構築2013
- Author(s)
  山元康敏、Prince LS, 奥田　司
- Organizer
  第3回　4大学連携研究フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591408
[Presentation] A cellular and molecular analysis for endothelial/mesenchymal plasticity.2013
- Author(s)
  Yamamoto Y, Prince LS, Okuda T.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591408
[Presentation] A Novel Cell Culture Model for Endothelial / Mesenchymal Plasticity2012
- Author(s)
  Yasutoshi Yamamoto, Lawrence S. Prince, and Tsukasa Okuda
- Organizer
  第85回　日本生化学大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590345
[Presentation] Evaluation of the biological role for arginine methylation of RUNX1/AML1 by hematopoietic rescue experiments2011
- Author(s)
  Mizutani S, Taniwaki M, Okuda T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21591214
[Presentation] Biological analysis of AML1/RUNX1 arginine-mutants by means of hematopoietic rescue experiments of Runx1-deficient mouse embryonic stem cells2011
- Author(s)
  Mizutani S, Taniwaki M, Okuda T
- Organizer
  第53回米国血液学会年次総会
- Place of Presentation
  サンディエゴ、米国
- Year and Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-21591214
[Presentation] Biological analysis of AML1-arginine mutant by means of Runx1 mutant of in vitro differentiation of mouse ES cells2011
- Author(s)
  Mizutani S, Taniwaki M, Okuda T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21591214
[Presentation] A search for associating molecules to the runt-domain of the leukemia-associated transcription factor, Runx1/AML12011
- Author(s)
  Nakamura K, Shiomi T, Okuda T
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21591214
[Presentation] Screening for interacting molecules of the hematopoiesis-associated transcription factor, Runx1/AML12010
- Author(s)
  Shiomi T, Nakamura K, Okuda T
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21591214
[Presentation] マウスES細胞のin vitro分化実験系を用いた造血関連転写因子AML1/Runx1の生物作用解析2007
- Author(s)
  奥田司
- Organizer
  第77回日本衛生学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591078

1. SAKAKURA Chouhei (10285257)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. Kuwahara Yasumichi (30590327)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
3. YOSHIDA TATSUSHI (80315936)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
4. CHIBA Tsutomu (30188487)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. HAGIWARA Akeo (90198648)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TANIWAKI Masafumi (80163640)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. YAMAMOTO Yasutoshi (50405247)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. SONODA Yoshiaki (60206688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TADAGAKI KENJIRO (30416268)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
10. 岡上武 (20150568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 小西英幸 (30295670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KODAMA Yuzou (80373687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KIMURA Takafumi (30275193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MURAKAMI Akira (60210001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YOKOTA Shohei (80231687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. INABA Toshiya (60281292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ITO Yoshiaki (80004612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MIZOBE Toshiki (50239266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HORIIKE Shigeo (10209273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 児玉裕三 (80378687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 阪口晃一 (00405284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 大里元美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 滝智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okuda Tsukasa 奥田 司

OKUDA Tsukasa 奥田 司

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Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.Principal Investigator

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Search for novel intervention methods for hematopoietic transcription control and research for its clinical applicationPrincipal Investigator

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RUNX1 as a molecular target for a novel hematopoietic reguationPrincipal Investigator

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Regulatory mechanisms of the leukemia-associated transcription factor, RUNX1/AML1, through the post-translational modifications.Principal Investigator

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Okuda Tsukasa 奥田司

OKUDA Tsukasa 奥田司