YAMADA KIYOFUMI 山田清文

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YAMADA Kiyofumi 山田清文

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Researcher Number	30303639
Other IDs
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Affiliation (Current)	2025: 藤田医科大学, 精神・神経病態解明センター, 客員教授
Affiliation (based on the past Project Information) *help	2024: 藤田医科大学, 精神・神経病態解明センター, 客員教授 2007 – 2023: Nagoya University, 医学部附属病院, 教授 2016: 名古屋大学, 大学院・医学系研究科, 教授 2013: 名古屋大学, 医学部付属病院, 教授 2007: Nagoya University, Graduate School of Medicine, Professor … More 2006: 金沢大学, 自然科学研究科, 教授 2004: Kanazawa University, Graduate School of Natural Science and Technology, Professor, 大学院・自然科学研究科, 教授 2004: 金沢大学, 自然科学研究科, 教授 2002 – 2003: 金沢大学, 薬学部, 教授 2001: 名古屋大学, 医学部・付属病院, 助教授 2001: University Hospital Associate Professor, 医学部・附属病院, 助教授 1999 – 2000: 名古屋大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator General pharmacology / Biological Sciences / Basic Section 48030:Pharmacology-related / General pharmacology / Neurochemistry/Neuropharmacology Except Principal Investigator Medical pharmacy / General pharmacology / Pharmacology in pharmacy / Biological pharmacy / Applied pharmacology / Hygiene / General pharmacology / Biological Sciences
Keywords	Principal Investigator 神経科学 / 統合失調症 / 脳神経疾患 / 動物モデル / アストロサイト / 神経発達障害 / メタンフェタミン / BDNF / Npas4 / IFITM3 … More / シナプス可塑性 / 薬物依存 / c-Fos / Fyn / 薬理学 / 意思決定 / 覚せい剤 / ドーパミン / ニコチン / モルヒネ / プラスミン / 組織プラスミノーゲン活性化因子 / 認知機能 / 神経スパイン / twinfilin-1 / リーリン / 抗精神病薬 / Ｒhoキナーゼ / ROCK2阻害薬 / Fasudil / 抗精神病作用 / Rhoキナーゼ / DREADD / Reelin / 注意機能 / MHC1 / DISC1 / タッチパネル式視覚弁別試験 / キンドリング / Homer1a / トランスジェニックマウス / イメージング創薬 / 周産期ウイルス感染モデル / 主要組織適合遺伝子複合体 / Hippocampus / B-Amy\|oid / NMDA receptors / Synaptic plasticity / Learning and memory / 放射状迷路学習 / アンチセンス / β-アミロイド蛋白 / 一酸化窒素 / 空間記憶 / 海馬 / β-アミロイド / NMDA受容体 / 学習記憶 / RabGDI / Ｆｓｔｌ１ / ＲａｂＧＤＩ / ＩＦＩＴＭ３ / DREADDシステム / 神経回路 / 大脳基底核 / 島皮質 / ストレス / 神経発達 / GABA受容体 / Follistatin like-1 / MMP3 / Fstl1 / 神経免疫 / ギャンブルテスト / 薬物依存症 / D-セリン / 炎症性サイトカイン / アストログリア / 神経－グリア相互作用 / エンドサイトーシス / polyI:C / 神経-グリア相互作用 / アストログリア細胞 / プロテインキナーゼA / ドーパミンD1受容体 / 認知症 / 覚せい剤精神病 / 禁断症状 / 報酬効果 / 高カリウム刺激 / 遺伝子欠損マウス / in vivo brain dialysis / ドパミン … More Except Principal Investigator アルツハイマー病 / RAGE / ABAD / β-アミロイド / 神経ステロイド / ストレス / 治療抵抗性 / モノアミン作動性神経 / グルコルチコイド / 神経再生 / N-メチル-D-アスパルギン酸（NMDA）受容体 / エピジェネティック制御機構 / グルタミン酸作動性神経系 / モノアミン作動性神経系 / 遺伝子発現解析 / 社会的敗北ストレス / 幼若期 / ニコチン受容体 / 覚せい剤 / ニコチン / 意思決定 / apoptosis / mitochondria / β-amyloid / neuron cultures / Alzheimer's disease / 透過性遷移孔 / アミロイドβペプチド / アポトーシス / ミトコンドリア / 神経細胞 / turner necrosis factor / inteiieikin-1β / synaptophysin / tyrosine nitration / inducible nitric oxide synthase / nitric oxide / alzheimer's disease / amyloid β protein / 学習記憶 / アセチルコリン / 誘導型NO合成酸素 / 一酸化炭素 / 腫瘍壊死因子 / インターロイキン-1β / シナプトフィジン / チロシンニトロ化 / 誘導型NO合成酵素 / 一酸化窒素 / βアミロイド / Drug dependence / Schizophrenia / Learning and memory / NMDA receptors / Stress / Neurosteroids / Sigma receptors / カッパーオビオイド受容体 / ニューロステロイド / カッパーオピオイド受容体 / 3beta-HSD / ストレス疾患モデル / ニューステロイド / 薬物依存 / 精神分裂病 / 学習・記憶 / NMDA受容体 / シグマ受容体 / アセチルコリン受容体 / 長期増強 / 海馬 / 治療法開発 / PREGS / アミロイドβ / 認知機能 / 抑うつ / 環境化学物質 / 神経新生 / ニューロン新生 / ブロモプロパン / リスク評価 / バイオマーカー / promoter / glucocorticoid / stress / NPAS4 / DNAメチル化 / プロモーター / グルココルチコイド / 転写制御 / Npas4 / ドパミン / 酵素免疫測定法 / 遺伝子改変マウス / 疾患マーカー / 遺伝子治療 / 精神疾患 / 神経疾患 / 新規分子 / 社会人 / 薬剤師 / 遠隔地教育 / オンデマンド放送 / カリキュラム / 医療薬学 / 大学院教育 / インターネット / 脳 / 酸化的ストレス / 記憶・学習 / 老化 / Klothoマウス Less

Study on the regulation mechanism of neural spine morphology and cognitive function by twinfilin-1Principal Investigator
- Principal Investigator
  
  山田清文
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fujita Health University
  Nagoya University
Genomic analysis-based neuropharmacological study on basal ganglia-thalamocortical circuits for new drug discovery in schizophreniaPrincipal Investigator
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Nagoya University
Development a translatable visual discrimination test in rodents to apply for drug discovery and developmentPrincipal Investigator
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Development of a new transgenic mouse model as a platform for the imaging-based drug discovery and developmentPrincipal Investigator
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
グリア細胞におけるMHCクラスⅠ分子の過剰発現とマイクロエンドフェノタイプPrincipal Investigator
- Principal Investigator
  
  山田清文
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Study on the neuronal circuit and molecular mechanis underlying decision-making and its application for drug developmentPrincipal Investigator
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Real-time imaging of the mechanism underlying neuroinflammation-induced neuropsychiatric disordersPrincipal Investigator
- Principal Investigator
  
  Yamada Kiyofumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Investigation in mechanism and therapeutic strategy into vulnerability to mood disorder after exposure to stress in the stage of neuro-development of mice
- Principal Investigator
  
  Nabeshima Toshitaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Fujita Health University
  Meijo University
ストレス応答性転写因子NPAS4欠損マウスにおけるGABA神経発達と表現型解析Principal Investigator
- Principal Investigator
  
  山田清文
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Effect of nicotine on reward-based decision-making in healthy and methamphetamine-treated rat
- Principal Investigator
  
  Mizoguchi Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nagoya University
アストログリア細胞のエンドサイトーシスの障害による神経発達障害Principal Investigator
- Principal Investigator
  
  山田清文
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
A study on a novel therapeutic strategy for Alzheimer's disease Using neurosteroids.
- Principal Investigator
  
  SOKABE Masahiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagoya University
Role of neuronal PAS domain 4 (Npas4) in psychiatric disorder.
- Principal Investigator
  
  HIBI YOKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Effect of drugs of abuse on reward-based decision-making in rodentsPrincipal Investigator
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Role of neurogenesis in mechanism of chronic or late-onset toxicity of environmental chemicals to the central nervous system
- Principal Investigator
  
  ICHIHARA Gaku
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Nagoya University
Functional analysis of IFITM3 in neurodevelopmental impairmentsPrincipal Investigator
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
神経・精神疾患に関与する新規分子の機能解明および臨床応用への可能性
- Principal Investigator
  
  NTTTA Atsumi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
ANALYSES OF DYNAMIC CHANGES AND THE FUNCTION OF TISSUE PLASMINOGEN ACTIVATOR IN ANIMAL MODELS OF DOPAMINE-RELATED MENTAL DISORDERSPrincipal Investigator
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Molecular mechanisms of mitochondrial dysfunction and neurotoxicity induced by Aβ-ARAD interaction
- Principal Investigator
  
  TAKUMA Kazuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kanazawa University
インターネットを活用した医療薬学系大学院教育カリキュラムの開発
- Principal Investigator
  
  木村和子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
可塑的脳機能変化における組織プラスミノーゲン活性化因子の役割Principal Investigator
- Principal Investigator
  
  山田清文
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kanazawa University
Brain dysfunction induced by tyrosine nitrosylation of synaptic protein
- Principal Investigator
  
  NABESHIMA Toshitaka
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
老化促進マウス(Klothoマウス)の脳機能解析
- Principal Investigator
  
  NABESHIMA Toshitaka
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Role of brain-derived neurotrophic factor (BDNF) in learning and memoryPrincipal Investigator
- Principal Investigator
  
  YAMADA Kiyofumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Role of NMDA and sigma receptors in the animal models for neuropsychological diseases.
- Principal Investigator
  
  NABESHIMA Toshitaka
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University

[Book] 実験薬理学実践行動薬理学(日本薬理学会編)(依存性薬物による精神障害の分子機序.)2010
- Author(s)
  永井拓、鍋島俊隆、山田清文
- Publisher
  金芳堂、京都
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Rho kinase inhibitors ameliorate cognitive impairment in a male mouse model of methamphetamine-induced schizophrenia2023
- Author(s)
  Liao Jingzhu、Dong Geyao、Zhu Wenjun、Wulaer Bolati、Mizoguchi Hiroyuki、Sawahata Masahito、Liu Yue、Kaibuchi Kozo、Ozaki Norio、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Pharmacological Research
  
  Volume: 194 Pages: 106838-106838
- DOI
  10.1016/j.phrs.2023.106838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-23K27360
[Journal Article] Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.2023
- Author(s)
  Tanaka R, Liao J, Hada K, Mori D, Nagai T, Matsuzaki T, Nabeshima T, Kaibuchi K, Ozaki N, Mizoguchi H, Yamada K.
- Journal Title
  
  Pharmacological Research
  
  Volume: 187 Pages: 106589-106589
- DOI
  10.1016/j.phrs.2022.106589
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-23K27360
[Journal Article] Genomic and Reverse Translational Analysis Discloses a Role for Small GTPase RhoA Signaling in the Pathogenesis of Schizophrenia: Rho-Kinase as a Novel Drug Target2023
- Author(s)
  Tanaka, R; Yamada, K
- Journal Title
  
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
  
  Volume: 24 Issue: 21 Pages: 15623-15623
- DOI
  10.3390/ijms242115623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19425, KAKENHI-PROJECT-23K27360
[Journal Article] New Strategies for the Treatment of Neuropsychiatric Disorders Based on Reelin Dysfunction2022
- Author(s)
  Tsuneura Yumi、Nakai Tsuyoshi、Mizoguchi Hiroyuki、Yamada Kiyofumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 3 Pages: 1829-1829
- DOI
  10.3390/ijms23031829
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428
[Journal Article] Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia.2022
- Author(s)
  Takase S, Liao J, Liu Y, Tanaka R, Miyagawa Y, Sawahata M, Sobue A, Mizoguchi H, Nagai T, Kaibuchi K, Ozaki N, Yamada K.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 15;931 Pages: 175207-175207
- DOI
  10.1016/j.ejphar.2022.175207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19749, KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Mice with exonic RELN deletion identified from a patient with schizophrenia have impaired visual discrimination learning and reversal learning in touchscreen operant tasks2022
- Author(s)
  Liao Jingzhu、Dong Geyao、Wulaer Bolati、Sawahata Masahito、Mizoguchi Hiroyuki、Mori Daisuke、Ozaki Norio、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 416 Pages: 113569-113569
- DOI
  10.1016/j.bbr.2021.113569
- NAID
  120007190677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Microinjection of Reelin into the mPFC prevents MK-801-induced recognition memory impairment in mice2021
- Author(s)
  Sawahata Masahito、Asano Hiroki、Nagai Taku、Ito Norimichi、Kohno Takao、Nabeshima Toshitaka、Hattori Mitsuharu、Yamada Kiyofumi
- Journal Title
  
  Pharmacological Research
  
  Volume: 173 Pages: 105832-105832
- DOI
  10.1016/j.phrs.2021.105832
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-19K07366, KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-21K19342
[Journal Article] Analysis of Reelin signaling and neurodevelopmental trajectory in primary cultured cortical neurons with RELN deletion identified in schizophrenia2021
- Author(s)
  Tsuneura Yumi、Sawahata Masahito、Itoh Norimichi、Miyajima Ryoya、Mori Daisuke、Kohno Takao、Hattori Mitsuharu、Sobue Akira、Nagai Taku、Mizoguchi Hiroyuki、Nabeshima Toshitaka、Ozaki Norio、Yamada Kiyofumi
- Journal Title
  
  Neurochemistry International
  
  Volume: 144 Pages: 104954-104954
- DOI
  10.1016/j.neuint.2020.104954
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-21K19342
[Journal Article] Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons2021
- Author(s)
  Hada K, Wulaer B, Nagai T, Itoh N, Sawahata M, Sobue A, Mizoguchi H, Mori D, Kushima I, Nabeshima T, Ozaki N, Yamada K.
- Journal Title
  
  Mol Brain
  
  Volume: 14(1) Issue: 1 Pages: 21-21
- DOI
  10.1186/s13041-021-00735-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21811, KAKENHI-PROJECT-20K16488, KAKENHI-PUBLICLY-19H05017, KAKENHI-PROJECT-19H03532, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-20K07082
[Journal Article] Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia2020
- Author(s)
  Masahito Sawahata, Daisuke Mori, Yuko Arioka, Hisako Kubo, Itaru Kushima, Kanako Kitagawa, Akira Sobue, Emiko Shishido, Mariko Sekiguchi, Akiko Kodama, Ryosuke Ikeda, Branko Aleksic, Hiroki Kimura, Kanako Ishizuka, Taku Nagai, Kozo Kaibuchi, Toshitaka Nabeshima, Kiyofumi Yamada, Norio Ozaki
- Journal Title
  
  Psychiatry and clinical neurosciences
  
  Volume: 1 Issue: 5 Pages: 1-10
- DOI
  10.1111/pcn.12993
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07384, KAKENHI-PROJECT-19K08072, KAKENHI-PROJECT-18K19511, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H05090, KAKENHI-PROJECT-18K15513, KAKENHI-PROJECT-19K21221, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K16625, KAKENHI-PROJECT-18H04040
[Journal Article] Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice2020
- Author(s)
  Wulaer Bolati、Hada Kazuhiro、Sobue Akira、Itoh Norimichi、Nabeshima Toshitaka、Nagai Taku、Yamada Kiyofumi
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 170-170
- DOI
  10.1186/s13041-020-00710-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16488, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-17H04252
[Journal Article] Reelin Supplementation Into the Hippocampus Rescues Abnormal Behavior in a Mouse Model of Neurodevelopmental Disorders2020
- Author(s)
  Ibi Daisuke、Nakasai Genki、Koide Nayu、Sawahata Masahito、Kohno Takao、Takaba Rika、Nagai Taku、Hattori Mitsuharu、Nabeshima Toshitaka、Yamada Kiyofumi、Hiramatsu Masayuki
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 14 Pages: 285-285
- DOI
  10.3389/fncel.2020.00285
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07332, KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-20H03428, KAKENHI-PROJECT-19K22504, KAKENHI-PROJECT-17H04252
[Journal Article] Nicotine and varenicline ameliorate changes in reward-based choice strategy and altered decision-making in methamphetamine-treated rats.2019
- Author(s)
  Mizoguchi H, Wang T, Kusaba M, Fukumoto K, Yamada K.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 359 Pages: 935-941
- DOI
  10.1016/j.bbr.2018.06.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H06053, KAKENHI-PROJECT-16H03303, KAKENHI-PROJECT-17H04031
[Journal Article] Methamphetamine use causes cognitive impairment and altered decision-making.2019
- Author(s)
  Mizoguchi H, Yamada K.
- Journal Title
  
  Neurochem Int.
  
  Volume: 124 Pages: 106-113
- DOI
  10.1016/j.neuint.2018.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H06053, KAKENHI-PROJECT-16H03303, KAKENHI-PROJECT-17H04031
[Journal Article] Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes.2018
- Author(s)
  A Sobue, N Ito, T Nagai, W Shan, K Hada, Nakajima A, Y Murakami, A Mouri, Y Yamamoto, T Nabeshima, K Saito, K Yamada
- Journal Title
  
  Glia
  
  Volume: 66 Issue: 5 Pages: 1034-52
- DOI
  10.1002/glia.23299
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-15H03086
[Journal Article] Pharmacological and proteomic analyses of neonatal polyI:C-treated adult mice.2018
- Author(s)
  Kitagawa, K., Nagai, T., Yamada, K.
- Journal Title
  
  Neurosci. Res.
  
  Volume: - Pages: 39-47
- DOI
  10.1016/j.neures.2018.10.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-17H04031
[Journal Article] Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis.2018
- Author(s)
  Mouri A, Ukai M, Uchida M, Hasegawa S, Taniguchi M, Ito T, Hida H, Yoshimi A, Yamada K, Kunimoto S, Ozaki N, Nabeshima T, Noda Y.
- Journal Title
  
  Neuropharmacology.
  
  Volume: 133 Pages: 23-37
- DOI
  10.1016/j.neuropharm.2018.01.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17J09360, KAKENHI-PROJECT-17H00512, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-16K08421
[Journal Article] Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia.2018
- Author(s)
  Sobue A, Kushima I, Nagai T, Shan W, Kohno T, Aleksic B, Aoyama Y, Mori D, Arioka Y, Kawano N, Yamamoto M, Hattori M, Nabeshima T, Yamada K, Ozaki N.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 13046-13046
- DOI
  10.1038/s41598-018-31390-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08281, KAKENHI-PROJECT-17K10295, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H03985, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-17K19500
[Journal Article] Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1Δ2-3/Δ2-3 mice2018
- Author(s)
  Wulaer B, Nagai T, Sobue A, Itoh N, Kuroda K, Kaibuchi K, Nabeshima T, Yamada K
- Journal Title
  
  Genes Brain Behav
  
  Volume: 印刷中 Issue: 8
- DOI
  10.1111/gbb.12478
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-18K14816, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-17K19483
[Journal Article] Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice2018
- Author(s)
  Bin Saifullah Md. Ali、Nagai Taku、Kuroda Keisuke、Wulaer Bolati、Nabeshima Toshitaka、Kaibuchi Kozo、Yamada Kiyofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 14413-14413
- DOI
  10.1038/s41598-018-32840-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14816, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-17K19483
[Journal Article] Innate immune activation of astrocytes impairs neurodevelopment via upregulation of follistatin-like 1 and interferon-induced transmembrane protein 3.2018
- Author(s)
  Yamada, S., Itoh, N., Nagai, T., Nakai, T., Ibi, D., Nakajima, A., Nabeshima, T., Yamada, K.
- Journal Title
  
  J. Neuroinflammation.
  
  Volume: 15 Issue: 1 Pages: 295-295
- DOI
  10.1186/s12974-018-1332-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483
[Journal Article] Valocin-containing protein (VCP) is a novel IQ motif containing GTPase activating protein 1 (IQGAP1) interacting protein.2017
- Author(s)
  Itoh, N., Nagai, T,, Watanabe, T., Taki, K., Nabeshima, N., Kaibuchi, K., Yamada, K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 493 Issue: 4 Pages: 1384-1389
- DOI
  10.1016/j.bbrc.2017.09.159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19483, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080
[Journal Article] Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors.2017
- Author(s)
  Shin EJ, Dang DK, Tran TV, Tran HQ, Jeong JH, Nah SY, Jang CG, Yamada K, Nabeshima T, Kim HC.
- Journal Title
  
  Arch. Pharm. Res.
  
  Volume: - Issue: 4 Pages: 403-428
- DOI
  10.1007/s12272-017-0897-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01284, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-16K15201
[Journal Article] Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole-induced epilepsy through the induction of Homer1a.2017
- Author(s)
  2.Shan W, Nagai T, Tanaka M, Itoh N, Furukawa-Hibi Y, Nabeshima T, Sokabe M, Yamada K.
- Journal Title
  
  J Neurochem.
  
  Volume: - Issue: 1 Pages: 19-33
- DOI
  10.1111/jnc.14274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-26460095, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17K08306, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17K19483
[Journal Article] High-dose dextromethorphan produces myelinoid bodies in the hippocampus of rats.2016
- Author(s)
  Tran HQ, Chung YH, Shin EJ, Kim WK, Lee JC, Jeong JH, Wie MB, Jang CG, Yamada K, Nabeshima T, Kim HC
- Journal Title
  
  J Pharmacol Sci,
  
  Volume: 132 Issue: 2 Pages: 166-170
- DOI
  10.1016/j.jphs.2016.10.001
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460240
[Journal Article] Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.2016
- Author(s)
  Aoyama Y, Toriumi K, Mouri A, Hattori T, Ueda E, Shimato A, Sakakibara N, Soh Y, Mamiya T, Nagai T, Kim HC, Hiramatsu M, Nabeshima T, Yamada K.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 41(2) Issue: 2 Pages: 578-89
- DOI
  10.1038/npp.2015.186
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08218, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26870878, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26860175, KAKENHI-PROJECT-26293053
[Journal Article] Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: The role of Girdin in the CNS.2016
- Author(s)
  Itoh N, Enomoto A, Nagai T, Takahashi M, Yamada K
- Journal Title
  
  Rev Neurosci
  
  Volume: - Issue: 5 Pages: 481-490
- DOI
  10.1515/revneuro-2015-0072
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01284, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26221304
[Journal Article] Protective potential of the glutathione peroxidase-1 gene in abnormal behaviors induced by phencyclidine in mice.2016
- Author(s)
  Tran TV, Shin EJ, Jeong JH, Lee JW, Lee Y, Jang CG, Nah SY, Lei XG, Toriumi K, Yamada K, Nabeshima T, Kim HC.
- Journal Title
  
  Mol Neurobiol.
  
  Volume: - Issue: 9 Pages: 7042-7062
- DOI
  10.1007/s12035-016-0239-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01284, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-26870878
[Journal Article] Insular neural system controls decision-making in healthy and methamphetamine-treated rats2015
- Author(s)
  Mizoguchi H, Katahira K, Inutsuka A, Fukumoto K, Nakamura A, Wang T, Nagai T, Sato J, Sawada M, Ohira H,Yamanaka A, Yamada K
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 (29) Issue: 29 Pages: 3930-3939
- DOI
  10.1073/pnas.1418014112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640041, KAKENHI-PUBLICLY-15H01428, KAKENHI-PUBLICLY-26118506, KAKENHI-PUBLICLY-26118507, KAKENHI-PUBLICLY-26120713, KAKENHI-PROJECT-24243068, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-25460094, KAKENHI-PROJECT-26860157, KAKENHI-PROJECT-25284003, KAKENHI-PROJECT-26293046, KAKENHI-PROJECT-26293053
[Journal Article] The piccolo intronic single nucleotide polymorphism rs13438494 regulates dopamine and serotonin uptake and shows associations with dependence-like behavior in genomic association study.2015
- Author(s)
  Uno K, Nishizawa D, Seo S, Takayama K, Matsumura S, Sakai N, Ohi K, Nabeshima T, Hashimoto R, Ozaki N, Hasegawa J, Sato N, Tanioka F, Sugimura H, Fukuda KI, Higuchi S, Ujike H, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Yamada M, Ikeda K, Miyamoto Y, Nitta A.
- Journal Title
  
  Curr Mol Med.
  
  Volume: 15 Pages: 265-274
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460240
[Journal Article] Therapeutic targets for neurodevelopmental disorders emerging from animal models with perinatal immune activation.2015
- Author(s)
  Ibi D and Yamada K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 16 Issue: 12 Pages: 1-12
- DOI
  10.3390/ijms161226092
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01284, KAKENHI-PROJECT-15H06719, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26293053
[Journal Article] Blonanserin ameliorates phencyclidine-induced visual-recognition memory deficits: the complex mechanism of blonanserin action involving D3-5-HT2A and D1-NMDA receptors in the mPFC2015
- Author(s)
  Hida H, Mouri A, Mori K, Matsumoto Y, Seki T, Taniguchi M, Yamada K, Iwamoto K, Ozaki N, Nabeshima T, Noda Y
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 40 Issue: 3 Pages: 601-613
- DOI
  10.1038/npp.2014.207
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590219, KAKENHI-PROJECT-26460240, KAKENHI-PLANNED-25117010, KAKENHI-PROJECT-25253072, KAKENHI-PROJECT-14J09449
[Journal Article] Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD).2015
- Author(s)
  Nakajima, A., Aoyama, Y., Shin, E.J. Nam, Y., Kim, H.C. Nagai, T., Yokosuka, A., Mimaki, Y., Yokoi, T., Ohizumi, Y., Yamada, K.
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 289 Pages: 69-77
- DOI
  10.1016/j.bbr.2015.04.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26670121
[Journal Article] Induction of interferone-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes.2014
- Author(s)
  Nakajima A, Ibi D, Nagai T, Yamada S, Nabeshima T, Yamada K
- Journal Title
  
  Eur. J. Pharmacol.
  
  Volume: 745 Pages: 166-175
- DOI
  10.1016/j.ejphar.2014.08.034
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26670121
[Journal Article] Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence2014
- Author(s)
  Toriumi K., Kondo M., Nagai T., Furukawa-Hibi Y., Mamiya T., Fukushima T., Takeda M., Nitta A., Yamada K., Nabeshima T.(他7名)
- Journal Title
  
  Int. J . Neuropsychopharmacol
  
  Volume: 17 Pages: 443-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Alterations of GABAergic and dopaminergic system in mutant mice with disruption of exons 2 and 3 of the Disc1 gene.2014
- Author(s)
  Nakai T, Nagai T, Wang R, Yamada S, Kuroda K, Kaibuchi K, Yamada K
- Journal Title
  
  Neurochem. Int.
  
  Volume: 74 Pages: 74-83
- DOI
  10.1016/j.neuint.2014.06.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-25830051, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26670121
[Journal Article] Girdin phosphorylation is crucial for synaptic plasticity and memory: A potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor2014
- Author(s)
  Tsuyoshi Nakai, Taku Nagai, Motoki Tanaka, Norimichi Itoh, Naoya Asai, Atsushi Enomoto, Masato Asai, Shinnnosuke Yamada, Ali Bin Saifullah, Masahiro Sokabe, Masahide Takahashi, Kiyofumi Yamada
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 34 Issue: 45 Pages: 14995-15008
- DOI
  10.1523/jneurosci.2228-14.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-26293053, KAKENHI-PROJECT-26670121, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-25460493
[Journal Article] Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat2014
- Author(s)
  Chang J, Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Aoki C, Yamada Y, Ichihara G, Kato M, Ichihara S
- Journal Title
  
  Diabetol Metab Syndr
  
  Volume: 6(1) Issue: 1 Pages: 8-8
- DOI
  10.1186/1758-5996-6-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390162, KAKENHI-PROJECT-23659326, KAKENHI-PROJECT-24406018, KAKENHI-PROJECT-24659300, KAKENHI-PROJECT-25293149, KAKENHI-PROJECT-25305020, KAKENHI-PROJECT-26293148, KAKENHI-PROJECT-26670329
[Journal Article] Matrix metalloproteinase-3 is a possible mediator of neurodevelopmental impairment due to polyl : C-induced innate immune activation of astrocytes2014
- Author(s)
  S Yamada, T Nagai, T Nakai, D Ibi, A Nakajima, K Yamada
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 38 Pages: 272-282
- DOI
  10.1016/j.bbi.2014.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-13J03699, KAKENHI-PUBLICLY-24111518, KAKENHI-PUBLICLY-25116515, KAKENHI-PROJECT-25460093
[Journal Article] SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization2014
- Author(s)
  K Toriumi, M Ikami, M Kondo, A Mouri, T Koseki, D Ibi, Y Furukawa-Hibi, T Nagai, T Mamiya, A Nitta, K Yamada and T Nabeshima
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 91 Issue: 12 Pages: 1525-1532
- DOI
  10.1002/jnr.23273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24590304
[Journal Article] Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence2014
- Author(s)
  Toriumi K, Kondo M, Nagai T, Hashimoto R, Ohi K, Song Z, Tanaka J, Mouri A, Koseki T, Yamamori H, Furukawa-Hibi Y, Mamiya T, Fukushima T, Takeda M, Nitta A, Yamada K, Nabeshima T
- Journal Title
  
  Int J Neuropsychopharmacol
  
  Volume: 17 Issue: 03 Pages: 443-453
- DOI
  10.1017/s1461145713001302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24590304, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25461730, KAKENHI-PROJECT-26460095
[Journal Article] Correlation of CYP2C19 Phenotype with Voriconazole Plasma Concentration in Children2013
- Author(s)
  Narita A., Muramatsu H., Sakaguchi H., Furukawa-Hibi Y., Yamada K. and Kojima S.(他9名)
- Journal Title
  
  J . Pediat. Hematol. Onc
  
  Volume: 35(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013
- Author(s)
  D Ibi, I Nagai, A Nakajima, H Mizoguchi, T Kawase, D Tsuboi, S Kano, Y Sato, M Hayakawa, U. C. Lange, D. J. Adams, M. Azim Surani, T Satoh, A Sawa, K Kaibuchi, T Nabeshima and K Yamada
- Journal Title
  
  Glia
  
  Volume: 61 Issue: 5 Pages: 679-693
- DOI
  10.1002/glia.22461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23591594, KAKENHI-PROJECT-23790290, KAKENHI-PROJECT-23791220, KAKENHI-PUBLICLY-24111518, KAKENHI-PROJECT-24657140
[Journal Article] Rats with metabolic syndrome resist the protective effects of N-acetyl l-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet.2013
- Author(s)
  Suzuki Y, Ichihara G, Sahabudeen SM, Kato A, Yamaguchi T, Imanaka-Yoshida K, Yoshida T, Yamada Y, Ichihara S.
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65 Issue: 7-8 Pages: 1173-1182
- DOI
  10.1016/j.etp.2013.05.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659326, KAKENHI-PROJECT-24406018
[Journal Article] Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse.2013
- Author(s)
  Akira Nakajima, Yuki Aoyama, Thuy-Ty Lan Nguyen, Eun Joo Shin, Hyoung-Chun Kim, Shinnosuke Yamada, Tsuyoshi Nakai, Taku Nagai, Akihiro Yokosuka, Yoshihiro Mimaki, Yasushi Ohizumi, Kiyofumi Yamada
- Journal Title
  
  Behavioura Brain Research.
  
  Volume: 250 Pages: 351-360
- DOI
  10.1016/j.bbr.2013.05.025
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111518
[Journal Article] Serial changes in adipocytokines and cardiac function in a rat model of the metabolic syndrome.2013
- Author(s)
  Yamaguchi T, Kitamori K, Ichihara G, Suzuki Y, Ochiai M, Yamada Y, Tada-Oikawa S, Tsuchikura S, Yamori Y, Ichihara S.
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 40 Issue: 7 Pages: 443-448
- DOI
  10.1111/1440-1681.12107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659326, KAKENHI-PROJECT-24406018, KAKENHI-PROJECT-25460798
[Journal Article] 周産期擬似ウィルス感染モデルにおける神経発達障害神経-グリア細胞相互作用におけるIFITM3の役割2013
- Author(s)
  山田清文
- Journal Title
  
  日本薬理誌
  
  Volume: 142 Pages: 221-225
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111518
[Journal Article] SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization2013
- Author(s)
  Toriumi K., Ikami M., Furukawa-Hibi Y., Nagai T., Mamiya T., Nitta A., Yamada K. and Nabeshima T.(他3名)
- Journal Title
  
  J . Neurosci. Res
  
  Volume: 91 Pages: 1525-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Neuronal PAS domain protein 4 (Npas4) regulates neurite outgrowth and phosphorylation of synapsin I2013
- Author(s)
  Yun, J., Nagai, T., Furukawa-Hibi, Y., Kuroda, K., Kaibuchi, K. and Yamada, K.
- Journal Title
  
  J . Biol. Chem
  
  Volume: 288 Pages: 2655-2664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Animal models of schizophrenia for molecular and pharmacological intervention and potential candidate molecules.2013
- Author(s)
  Mouri, T Nagai, D Ibi, K Yamada.
- Journal Title
  
  Neurobiol. Dis.
  
  Volume: 53 Pages: 61-74
- DOI
  10.1016/j.nbd.2012.10.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23791325
[Journal Article] Neuronal PAS domain domain protein 4 (Npas4) regulates neurite outgrowth and phosphorylation of synapsin I.2013
- Author(s)
  Yun J, Nagai T, Furukawa-Hibi Y, Kuroda K, Kaibuchi K, Greenberg ME, and Yamada K
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 4 Pages: 2655-2664
- DOI
  10.1074/jbc.m112.413310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23659135, KAKENHI-PROJECT-23790081, KAKENHI-PROJECT-25830051
[Journal Article] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter2012
- Author(s)
  Furukawa-Hibi, Y., Yun, J., Nagai, T. and Yamada, K.
- Journal Title
  
  J . Neurochem
  
  Volume: 123 Pages: 866-875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist-bound glucocorticoid receptor to its promoter2012
- Author(s)
  Furukawa-Hibi Y, Yun J, Nagai T, and Yamada K
- Journal Title
  
  J Neurochem
  
  Volume: 123 Issue: 5 Pages: 866-875
- DOI
  10.1111/jnc.12034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23790081
[Journal Article] Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia2012
- Author(s)
  Doisaki S, Muramatsu H, Shimada A, Takahashi Y, Mori-Ezaki M, Sato M, Kawaguchi H, Kinoshita A, Sotomatsu M, Hayashi Y, Furukawa-Hibi Y, Yamada K, Hoshino H, Kiyoi H, Yoshida N, Sakaguchi H, Narita A, Wang X, Ismael O, Xu Y, Nishio N, Tanaka M, Hama A, Koike K, Kojima S
- Journal Title
  
  Blood
  
  Volume: 120 Issue: 7 Pages: 1485-1488
- DOI
  10.1182/blood-2012-02-406090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-23591536, KAKENHI-PROJECT-23591537, KAKENHI-PROJECT-23591552, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24390260, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24591387, KAKENHI-PROJECT-24791054
[Journal Article] Absence of SHATI/Nat8l reduces social interaction in mice2012
- Author(s)
  Furukawa-Hibi, Y., Nitta, A., Furukawa, S., Nabeshima, T. and Yamada, K.(他3名)
- Journal Title
  
  Neurosci. Lett
  
  Volume: 526 Pages: 79-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] D-Serine Ameliorates Neonatal PolyI:C Treatment–Induced Emotional and Cognitive Impairments in Adult Mice2012
- Author(s)
  Nagai T, Yu J, Kitahara Y, Nabeshima T and Yamada K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 120 Issue: 3 Pages: 213-227
- DOI
  10.1254/jphs.12142FP
- NAID
  10031147568
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23659135
[Journal Article] Repeated treatment with nicotine induces phosphorylation of NMDA receptor NR2B subunit in the brain regions involved in behavioral sensitization.2012
- Author(s)
  Nakajima A, Kinugasa Y, Torii J, Hishinuma T, Tomioka Y, Yamada K and Yamakuni T
- Journal Title
  
  Neurosci. Lett
  
  Volume: 524 Issue: 2 Pages: 133-138
- DOI
  10.1016/j.neulet.2012.07.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659135
[Journal Article] Absence of SHATI/Nat8l reduces social interaction in mice.2012
- Author(s)
  Furukawa-Hibi Y, Nitta A, Fukumitsu H, Somiya H, Toriumi K, Furukawa S, Nabeshima T, Yamada K.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 526 Issue: 2 Pages: 79-84
- DOI
  10.1016/j.neulet.2012.08.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659213, KAKENHI-PROJECT-23590299
[Journal Article] ストレスにより誘発される脳機能障害とストレス応答性転写因子Npas4の機能解析2012
- Author(s)
  永井拓, 尹在錫, 衣斐大祐, 小池宏幸, 日比陽子, 山田清文
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 139 Pages: 147-151
- NAID
  10030572362
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat.2012
- Author(s)
  Chang J, Oikawa S, Ichihara G, Nanpei Y, Hotta Y, Yamada Y, Tada-Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Ichihara S.
- Journal Title
  
  Nutr Metab (Lond).
  
  Volume: 9（1） Issue: 1 Pages: 87-87
- DOI
  10.1186/1743-7075-9-87
- NAID
  120006667439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390120, KAKENHI-PROJECT-23390162, KAKENHI-PROJECT-23659326, KAKENHI-PROJECT-23890082, KAKENHI-PROJECT-24406018, KAKENHI-PROJECT-24659300
[Journal Article] Effects of sub-acute and sub-chronic inhalation of 1-bromopropane on neurogenesis in adult rats.2012
- Author(s)
  L Zhang, T Nagai, K Yamada, D Ihi, S Ichihara K Subramanian.
- Journal Title
  
  Toxicology
  
  Volume: 304C Pages: 76-82
- DOI
  10.1016/j.tox.2012.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-22390120, KAKENHI-PROJECT-23659326, KAKENHI-PROJECT-24406018
[Journal Article] Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia2012
- Author(s)
  Doisaki, S., Muramatsu, H., Shimada, A., Furukawa-Hibi, Y., Yamada, K., Tanaka, M., Hama, A., Koike, K. and Kojima, S.(他16名)
- Journal Title
  
  Blood
  
  Volume: 120(7) Pages: 1485-1488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] 神経系におけるブチリルコリンエステラーゼの機能2012
- Author(s)
  日比陽子、山田清文
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 30 Pages: 672-674
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome2012
- Author(s)
  Iriyama, C., Tomita, A., Furukawa-Hibi, Y., Yamada, K., Kiyoi, H., Naoe, T.(他2名)
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 419(4) Pages: 662-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome2012
- Author(s)
  Chisako Iriyama
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: (in press) Issue: 4 Pages: 662-669
- DOI
  10.1016/j.bbrc.2012.02.071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591198, KAKENHI-PROJECT-23590299, KAKENHI-PROJECT-24591387
[Journal Article] 神経系におけるブチリルコリンエステラーゼの機能2012
- Author(s)
  日比陽子, 山田清文
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 30(6) Pages: 672-674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus2011
- Author(s)
  H Mizoguchi, J Nakade, M Tachibana, D Ibi, E Someya, H Koike, H Kamei, T Nabeshima, S Itohara, K Takuma, M Sawada, J Sato, K Yamada
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31 Issue: 36 Pages: 12963-12971
- DOI
  10.1523/jneurosci.3118-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23650190, KAKENHI-PROJECT-23659135, KAKENHI-PROJECT-23790082
[Journal Article] Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice.2011
- Author(s)
  Furukawa-Hibi, Y., Alkam T., Nitta, A., Matsuyama, A., Mizoguchi, H., Suzuki, K., Moussaoui, S., Yu, Q-S., Greig, N., Nagai, T. and Yamada, K.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] The hydrophobic dipeptide Leu-Ile inhibits immobility induced by repeated forced swimming via the induction of BDNF.2011
- Author(s)
  Furukawa-Hibi, Y., Nitta, A., Ikeda, T., Morishita, K., Liu W, Ibi D., Alkam, T., Nabeshima, T., and Yamada, K.
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 220 Pages: 271-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Butrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-βpeptide in mice2011
- Author(s)
  Yoko Furukawa-Hibi, et al
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Issue: 1 Pages: 222-229
- DOI
  10.1016/j.bbr.2011.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23659135
[Journal Article] Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-βpeptide in mice2011
- Author(s)
  Furukawa-Hibi, Y., Alkam T., Nitta, A., Nagai, T. and Yamada, K.(他6名)
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 225 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment2011
- Author(s)
  Nagai T, Kitahara Y, Ibi D, Nabeshima T, Sawa A and Yamada K
- Journal Title
  
  Behav Brain Res
  
  Volume: 225 Issue: 1 Pages: 305-310
- DOI
  10.1016/j.bbr.2011.07.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390046
[Journal Article] Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer’s disease, and epilepsy.2011
- Author(s)
  Mizoguchi H, Yamada K and Nabeshima T
- Journal Title
  
  Biochem. Res. Int.
  
  Volume: 2011 Pages: 681385-681385
- DOI
  10.1155/2011/681385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659135, KAKENHI-PROJECT-23790082
[Journal Article] The hydrophobic dipeptide Leu-Ile inhibits immobility induced by repeated forced swimming via the induction of BDNF2011
- Author(s)
  Furukawa-Hibi, Y., Nitta, A., Ikeda, T., Nabeshima, T., and Yamada, K.(他4名)
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 220 Pages: 271-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590299
[Journal Article] Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice : a possible involvement of a brain specific transcription factor Npas4.2010
- Author(s)
  Yun J, Koike H, Ibi D, Toth E, Mizoguchi H, Nitta A, Yoneyama M, Ogita K, Yoneda Y, Nabeshima T, Nagai T, Yamada K
- Journal Title
  
  J.Neurochem 114
  
  Pages: 1840-1851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.2009
- Author(s)
  Ibi D, Nagai T, Kitahara Y, Mizoguchi H, Koike H, Shiraki A, Takuma K, Kamei H, Noda N, Nitta A, Nabeshima T, Yoneda Y, Yamada K
- Journal Title
  
  Neurosci.Res. 64
  
  Pages: 297-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article]2009
- Author(s)
  山田清文, 溝口博之
- Journal Title
  
  臨床精神薬理ハンドブック第2版(医学書院)
  
  Pages: 78-83
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Matrix metalloprotease-9 inhibition improves amyloid.-mediated cognitive impairment and neurotoxicity in mice.2009
- Author(s)
  Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa K, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Exp.Ther. 331
  
  Pages: 14-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Therapeutic potential of nicotine for methamphetamine-induced impairment of sensorimotor gating : involvement of pallidotegmental neurons.2009
- Author(s)
  Mizoguchi H, Arai S, Koike H, Ibi D, Kamei H, Nabeshima T, Kim HC, Takuma K, Yamada K
- Journal Title
  
  Psychopharmacology 207
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Basic and translational research on proteinase-activated receptors : Regulation of nicotine reward by the tissue plasminogen activator (tPA)-plasmin system via proteinase-activated receptor 12008
- Author(s)
  Nagai T, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Sci. 108
  
  Pages: 408-414
- NAID
  10025732467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Tissue plasminogen activator is not involved in methamphetamine-induced neurotoxicity.2008
- Author(s)
  Fukakusa A, Mizoguchi H, Koike H, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Pharmacol.Sci. 106
  
  Pages: 321-324
- NAID
  10024318646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Basic and translational research on proteinase-activated receptors : Regulation of nicotine reward by the tissue plasminogen activator (tPA)-plasmin system via proteinase-activated receptor 1.2008
- Author(s)
  Nagai T, Nabeshima T, Yamada K
- Journal Title
  
  J.Pharmacol.Sci. 108
  
  Pages: 408-414
- NAID
  10025732467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.2008
- Author(s)
  Fukakusa A, Nagai T, Mizoguchi H, Otsuka N, Kimura H, Kamei H, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 436-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice.2008
- Author(s)
  Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, Kamei H, Nagai T, Yoneda Y, Nabeshima T, Yamada K
- Journal Title
  
  J.Neurochem. 105
  
  Pages: 921-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Ginkgo biloba extract EGb761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats.2007
- Author(s)
  Takuma K, Hoshina, Y, Arai S, Himeno Y, Matsuo, A, Funatsu Y, Kitahara Y, Ibi, D, Hayase M, Kamei H, Mizoguchi H, Nagai T, Koike K, Inoue M, Yamada K
- Journal Title
  
  Neuroscience 149
  
  Pages: 256-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Activation of post-synaptic dopamine D1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling.2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem. 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Activation of post-synaptic dopamine D_1 receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling2007
- Author(s)
  Ito M, Nagai T, Mizoguchi H, Sato K, Hayase M, Otsuka N, Fukakusa A, Kumagai N, Kim H-C, Nabeshima T, Takuma K, Yamada K
- Journal Title
  
  J.Neurochem 103
  
  Pages: 2589-2596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390062
[Journal Article] Amyloid pathology and protein kinase C(PKC) : possible therapeutic effects of PKC activators.2005
- Author(s)
  Olariu A, Yamada K, Nabeshima T.
- Journal Title
  
  J Pharmacol Sci. 97
  
  Pages: 1-5
- NAID
  10025724874
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Molecular mechanism of amyloid β-peptide-induced impairment of neurotransmission and memory in relation to oxidative stress.2005
- Author(s)
  Yamada, K. et al.
- Journal Title
  
  Progress in Alzheimer's and Parkinson's Disease (in press)
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Effects of memantine and donepezil on amyloid β-induced memory impairment in a delayed-matching to position task in rats.2005
- Author(s)
  Yamada K et al.
- Journal Title
  
  Behav Brain Res. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] The role of tissue plasminogen activator in methamphetamine-related reward and sensitization.2005
- Author(s)
  Nagai T, Noda Y, Ishikawa K, Miyamoto Y, Yoshimura M, Ito M, Takayanagi M, Takuma K, Yamada K, Nabeshima T.
- Journal Title
  
  J Neurochem. 92
  
  Pages: 660-667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Role of tumor necrosis factoi-α in methamphetamine-induced drug dependence and neurotoxicity.2004
- Author(s)
  Nakajima A, Yamada K, Nagai T, Uchiyama T, Miyamoto Y, Mamiya T, He J, Nitta A, Mizuno M, Tran M.H, Seto A, Yoshimura M, Kitaichi K, Hasegawa T, Saito K, Yamada Y, Seishima M, Sekikawa K, Kim H.C, Nabeshima T.
- Journal Title
  
  J Neurosci. 24
  
  Pages: 2212-2225
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Anatomical substrates for the discriminative stimulus effects of methamphetamine in rats.2004
- Author(s)
  Nakajima A, Yamada K, He J, Zeng N, Nitta A, Nabeshima T.
- Journal Title
  
  J Neurochem. 91
  
  Pages: 308-317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Enhanced antidepressant efficacy of σ 1 receptor agonists in rats after chronic intracerebroventricular infusion of βamyloid-(1-40) protein.2004
- Author(s)
  Urani A, Romieu P, Roman F.J, Yamada K, Noda Y, Kamei H, Tran H, Nagai T, Nabeshima T, Maurice T.
- Journal Title
  
  Eur J Pharmacol. 486
  
  Pages: 151-161
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Learning and Memory Alzheimer's Disease and Dementia September 14,(2003)2004
- Author(s)
  Yamada K, Mizuno M, Nabeshima T.
- Journal Title
  
  Methods Find Exp Clin Pharmacol (supple.2)
  
  Pages: 55-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Oxidative Stress Mechanism of Amyloid β-Peptide-Induced Impairment of Neurotransmission and Memory.2004
- Author(s)
  Nabeshima T, Tran MH, Kim HC, Yamada K
- Journal Title
  
  Methods Find Exp Clin Pharmacol (supple.2)
  
  Pages: 29-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Interaction of BDNF/TRKB signaling NMDA receptors in Learning and Memory.2004
- Author(s)
  Yamada, K. et al.
- Journal Title
  
  Drug News Perspect 17
  
  Pages: 435-438
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Role for brain-derived neurotrophic factor in learning and memory.2004
- Author(s)
  Yamada, K., Mizuno, M., Nabeshima, T.
- Journal Title
  
  Life Sci.Minireview 70
  
  Pages: 735-744
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Nitric oxide in learning and memory.2004
- Author(s)
  Yamada, K et al.
- Journal Title
  
  Memories are made of These : From Messengers to Molecules
  
  Pages: 480-491
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Interaction of BDNF/TRKB signaling NMDA receptors in Learning and Memory.2004
- Author(s)
  Yamada, K., Nabeshima, T.
- Journal Title
  
  Drug News Perspect 17
  
  Pages: 435-438
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Axonal regrowth downregulates the synthesis of glial cell line-derived neurotrophic factor in the lesioned rat sciatic nerve.2004
- Author(s)
  Yamada Y et al.
- Journal Title
  
  Neurosci Lett. 364
  
  Pages: 11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Regulations of methamphetamine reward by extracellular signal-regulated kinase 1/2/ets-like gene-1 signaling pathway via the activation of dopamine receptors.2004
- Author(s)
  Mizoguchi H, Yamada K, Mizuno M, Mizuno T, Nitta A, Noda Y, Nabeshima T.
- Journal Title
  
  Mol Pharmacol. 65
  
  Pages: 1293-1301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Learning and Memory Alzheimer's Disease and Dementia.2004
- Author(s)
  Yamada, K. et al.
- Journal Title
  
  Methods Find Exp Clin Pharmacol. (supple.2)
  
  Pages: 55-64
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Behavioural adaptations to addictive drugs in mice lacking the NMDA receptorel subunit.2004
- Author(s)
  Miyamoto Y, Yamada K, Nagai T, Mori H, Mishina M, Furukawa H, Noda Y, Nabeshima T.
- Journal Title
  
  Eur J Neurosci. 19
  
  Pages: 151-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] The interaction between the cholinergic and dopaminergic system in learning and memory process in rats.2004
- Author(s)
  Hefco V, Yamada K, Hefco A, Hritcu L, Tiron A, Nabeshima T.
- Journal Title
  
  Rom J Physiol. 41
  
  Pages: 21-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release.2004
- Author(s)
  Nagai T, Yamada K, Yoshimura M, Ishikawa K, Miyamoto Y, Hashimoto K, Nitta A, Noda Y, Nabeshima T.
- Journal Title
  
  Proc Natl Acad Sci USA. 101
  
  Pages: 3650-3655
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Axonal regrowth downregulates the synthesis of glial cell line-derived neurotrophic factor in the lesioned rat sciatic nerve.2004
- Author(s)
  Yamada Y, Shimizu K, Nitta A, Soumiya H, Fukumitsu H, Furukawa S. Related Articles, Links
- Journal Title
  
  Neurosci Lett. 364
  
  Pages: 11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Tissue plasminogen activator(t-PA) is involved in morphine-induced rewarding effects.2004
- Author(s)
  Yan Y, Nitta A, Yamada K, Mizoguchi H, Nagai T, Nabeshima T.
- Journal Title
  
  Jpn J Neuropsychopharmacol. 24
  
  Pages: 314-314
- NAID
  10015423825
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Nitric oxide in learning and memory.2004
- Author(s)
  Yamada, K et al.
- Journal Title
  
  in "Memories are made of These : From Messengers to Molecules"
  
  Pages: 480-449
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] β-Amyloid(1-42)-induced learning and memory deficits in mice : involvement of oxidative burdens in the hippocampus and cerebral cortex.2004
- Author(s)
  Jhoo J H, Kim H-C, Nabeshima T, Yamada K, Shin E-J, Jhoo W-K, Kim W, Kang K-S, Jo S A, Woo J I.
- Journal Title
  
  Behav Brain Res. 155
  
  Pages: 185-196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Role for brain-derived neurotrophic factor in learning and memory.2004
- Author(s)
  Yamada, K. et al.
- Journal Title
  
  Life Sci.Minireview 70
  
  Pages: 735-744
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Learning and Memory Alzheimer's Disease and Dementia.2004
- Author(s)
  Yamada K. et al.
- Journal Title
  
  in "Methods Find Exp Clin Pharmacol." (supple.2)
  
  Pages: 55-64
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Nitric oxide in learning and memory2004
- Author(s)
  Yamada, K., Nabeshima, T.
- Journal Title
  
  Memories are made of These : From Messengers to Molecules(Ed.by Riedel, G.and Platt, B.)(Landes Bioscience, Texas, U.S.A.)
  
  Pages: 480-491
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Immunocytochemical evidence that amyloid β(1-42) impairs endogenous antioxidant systems in vivo.2003
- Author(s)
  Kim H.-C, Yamada K, Nitta A, Olariu A, Tran M.H, Mizuno M, Nakajima A, Nagai T, Kamei H, Jhoo W.-K, Im D.-H, Shin E.-J, Hjelle O.P, Ottersen O.P, Park S.C, Kato K, Mirault M.-E, Nabeshima, T.
- Journal Title
  
  Neuroscience 119
  
  Pages: 399-419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid β-peptide-induced cholinergic dysfunction.2003
- Author(s)
  Tran M.H, Yamada K, Nakajima A, Mizuno M, He J.Kamei H, Nabeshima T.
- Journal Title
  
  Mol Psychiatry 8
  
  Pages: 407-412
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Brain-derived neurotrophic factor/TrkB signaling in memory process.2003
- Author(s)
  Yamada, K., Nabeshima, T.
- Journal Title
  
  J.Pharmacol.Sci. 91
  
  Pages: 267-270
- NAID
  130000073684
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Brain-derived neurotrophic factor/TrkB signaling in memory Process.2003
- Author(s)
  Yamada, K et al.
- Journal Title
  
  J.Pharmacol.Sci. 91
  
  Pages: 267-270
- NAID
  130000073684
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Phosphatidylinositol 3-kinase : a molecule mediating BDNF-dependent spatial memory formation.2003
- Author(s)
  Mizuno M, Yamada K, Takei N, Tran M.H, He J, Nakajima A, Nawa H, Nabeshima T.
- Journal Title
  
  Mol Psychiatry 8
  
  Pages: 217-224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Involvement of BDNF receptor TrkB in spatial memory formation2003
- Author(s)
  Mizuno M, Yamada K, He J, Nakajima A, Nabeshima T.
- Journal Title
  
  Learn Mem. 10
  
  Pages: 108-115
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Development of anti-dementia drugs for Alzheimer's disease : Present and future2002
- Author(s)
  Nabeshima, T., Yamada, K.
- Journal Title
  
  Mapping the Progress of Alzheimer's and Parkinson's Disease(Ed.by Mizuno et al.)(Kluwer Academic/Plenum Publishers, New York)
  
  Pages: 223-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Therapeutic approaches to the treatment of Alzheimer's disease.2002
- Author(s)
  Yamada K. et al.
- Journal Title
  
  Drugs of Today 38
  
  Pages: 631-637
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Role of inducible nitric oxide synthase in β-amyloid-induced brain dysfunction in rats.2002
- Author(s)
  Yamada K. et al.
- Journal Title
  
  in "Mapping the Progress of Alzheimer's and Parkinson's Disease"
  
  Pages: 121-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Role of inducible nitric oxide synthase in β-amyloid-induced brain dysfunction in rats2002
- Author(s)
  Yamada, K., Tran, M.H., Kim, H-C., Nabeshima, T.
- Journal Title
  
  Mapping the Progress of Alzheimer's and Parkinson's Disease(Ed.by Mizuno et al.)(Kluwer Academic/Plenum Publishers, New York)
  
  Pages: 121-126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Memory impairment induced by chronic intracerebroventricular infusion of beta-amyloid (1-40) involves downregulation of protein kinase C.2002
- Author(s)
  Olariu A, Yamada K, Mamiya T, Hefco V, Nabeshima T.
- Journal Title
  
  Brain Res. 957
  
  Pages: 278-286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Therapeutic approaches to the treatment of Alzheimer's disease.2002
- Author(s)
  Yamada, K., Nabeshima, T.
- Journal Title
  
  Drugs of Today 38
  
  Pages: 631-637
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Molecular mechanism of amyloid β-peptide-induced impairment of neurotransmission and memory in relation to oxidative stress.
- Author(s)
  Yamada, K. et al.
- Journal Title
  
  Progress in Alzheimer's and Parkinson's Disease (in press)
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Molecular mechanism of amyloid β-peptide-induced impairment of neurotransmission and memory in relation to oxidative stress.
- Author(s)
  Yamada, K. et al.
- Journal Title
  
  in "Progress in Alzheimer's and Parkinson's Disease" (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Effects of memantine and donepezil on amyloid β-induced memory impairment in a delayed-matching to position task in rats.
- Author(s)
  Yamada K et al.
- Journal Title
  
  Behav Brain Res. (in press)
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Effects of memantine and donepezil on amyloid β-induced memory impairment in a delayed-matching to position task in rats.
- Author(s)
  Yamada K, Takayanagi M., Kamei H, Nagai T, Dohniwa M., Kobayashi K., Yoshida S., Ohhara T., Takauma K.Nabeshima T.
- Journal Title
  
  Behav Brain Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Journal Article] Molecular mechanism of amyloid-β peptide-induced impairment of neurotransmission and memory in relation to oxidative stress
- Author(s)
  Yamada K, Kim H-C, Nabeshima T.
- Journal Title
  
  Progress in Alzheimer's and Parkinson's Disease(Ed by I.Hanin, R.Cacabelos and A.Fisher)(The Parthenon Publishing Group, Lanlaster) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370031
[Presentation] Twinfilin 1 Phosphorylation is Crucial For Reelin Signaling In The Regulation Of Spine Morphology And Cognitive Function2023
- Author(s)
  Kiyofumi Yamada, Geyao Dong, Norimichi Itoh, Takaaki Matsui, Ayato Sato,Tetsuo Matsuzaki , Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai, Norio Ozaki, Toshitaka Nabeshima
- Organizer
  The 34th CINP World Congress of Neuropsychopharmacology (CINP2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] 統合失調症のゲノム解析に基づく創薬への挑戦2023
- Author(s)
  山田　清文
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] Comprehensive phosphoproteomic analysis in reelin mutant mice identified an important role of twinfilin 1 in spine development and actin dynamics.2023
- Author(s)
  Geyao Dong, Norimichi Itoh, Takaaki Matsui, Ayato　Sato, Tetsuo Matsuzaki, Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  The 34th CINP World Congress of Neuropsychopharmacology (CINP2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] 病態モデル動物を用いた精神疾患のメカニズムの解明と創薬研究2023
- Author(s)
  山田　清文
- Organizer
  第17回次世代を担う若手のための医療薬科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K27360
[Presentation] Neuronal morphological impairments in the model mice carrying the same deletion of RELN gene that was identified in a Japanese schizophrenia patient.2022
- Author(s)
  朱　悠韻、常浦　祐未、溝口　博之、澤幡　雅仁、森　大輔、河野　孝夫、服部　光治、鍋島　俊隆、尾崎　紀夫、山田　清文
- Organizer
  第142回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Arhgap10遺伝子変異マウスの神経活動の解析にむけたin vivoカルシウムイメージング法の確立2022
- Author(s)
  田中里奈子、羽田和弘、溝口博之、澤幡雅仁、永井拓、森大輔、鍋島俊隆、貝淵弘三、尾崎紀夫、山田清文
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Phosphorylated twinfilin1 plays a major role in dendritic spine development, but not brain layer formation2022
- Author(s)
  Geyao Dong, Norimichi Itoh, Tetsuo Matsuzaki, Hiroyuki Mizoguchi, Daisuke Mori, Taku Nagai,Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Phosphorylation of twinfilin-1 involved in the reelin signaling plays a crucial role in spine development2022
- Author(s)
  Geyao Dong, Norimichi Itoh, Hiroyuki Mizoguchi , Tetsuo Matsuzaki, Daisuke Mori, Taku Nagai, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
- Organizer
  JPW2022
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Spine morphological changes in Reln-del mice（リーリンモデルマウスにスパインの形態変化について研究）2022
- Author(s)
  Youyun Zhu、Yumi Tsuneura、Hiroyuki Mizoguchi、Masahito Sawahata、Daisuke Mori、Takao Kohno、Mitsuharu Hattori、Toshitaka Nabeshima、Norio Ozaki、Kiyofumi Yamada.
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] The Mice Carrying Schizopherenia-associated Mutation of Arhgap10 Gene are Vulnerable to Psychostimulants:Association with Morphological Abnormalities in Striatal Neurons.2021
- Author(s)
  Kiyofumi Yamada, Kazuhiro Hada, Taku Nagai
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Development of ADAMTS-3 Knockdown Method for Enhancement of Reelin Signaling in vitro.2021
- Author(s)
  Yumi Tsuneura, Masahito Sawahata, Norimichi Ito, Takao Kohno, Mitsuharu Hattori, Taku Nagai, Kiyofumi Yamada.
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] MK-801処置マウスの統合失調症様行動及び側坐核における神経伝達物質遊離に対するRhoキナーゼ阻害剤ファスジルの効果2021
- Author(s)
  田中里奈子、澤幡雅仁、高瀨冴子、Liu Yue、羽田和弘、溝口博之、永井拓、鍋島俊隆、尾崎紀夫、山田清文
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] The Mice Carrying Schizopherenia-associated Mutation of Arhgap10 Gene are Vulnerable to Psychostimulants: Association with Morphological Abnormalities in Striatal Neurons.2021
- Author(s)
  Kiyofumi Yamada, Kazuhiro Hada, Taku Nagai
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Comprehensive Phosphoproteomic Analysis in Reelin Mutant Mice Revealed a Crucial Role of Twinfilin-1 in Spine Development.2021
- Author(s)
  Norimichi Ito, Takaaki Matsui, Ayato sato, Kazuhiro Hada, Yumi Tsuneura, Taku Nagai, Toshitaka Nabeshima, Kiyofumi Yamada
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Comprehensive Phosphoprotemic Analysis in Reelin Mutant Mice Revealed a Crucial Rolr of Twinfilin-1 in Spine Development.2021
- Author(s)
  Norimichi Ito、Takaaki Matsui、Ayato sato、Kazuhiro Hada、Yumi Tsuneura、Taku Nagai、Toshitaka Nabeshima、Kiyofumi Yamada
- Organizer
  CINP2021 VIRTUAL WORLD CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03428
[Presentation] Acute administration of methamphetamine impairs higher cognitive function in C57BL/6J mice through cortico-striatal circuits.2019
- Author(s)
  Jingzhu Liao,Taku Nagai,Bolati Wulaer,Toshitaka Nabeshima,Kiyofumi Yamada
- Organizer
  Society for Neuroscience (SfN) Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] Roots of decision-making in addiction:the insular cortex,nucleus accumbens,striatum.2019
- Author(s)
  Hiroyuki Mizoguchi,Kiyofumi Yamada
- Organizer
  7TH INTERNATIONAL DRUG ABUSE RESEARCH SOCIETY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] Reelin supplementation therapy in preclinical models of schizophrenia.2019
- Author(s)
  Kiyofumi Yamada,Masahito Sawahata,Taku Nagai,Daisuke Ibi,Masayuki Hiramatsu
- Organizer
  6th Congress of AsCNP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] Evaluation of cognitive function in preclinical animal models of schizophrenia using touchscreen-based visual discrimination tasks.2019
- Author(s)
  Jingzhu Liao,Taku Nagai,Daisuke Mori,Bolati Wulaer,Toshitaka Nabeshima,Norio Ozaki,Kiyofumi Yamada
- Organizer
  The7th China-Japan Joint Meeting of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] A novel animal model of schizophrenia based on copy-number variations.2019
- Author(s)
  Taku Nagai,Akira Sobue,Daisuke Mori,Kazuhiro Hada,Jingzhu LIAO,Bolati Wulaer,Toshitaka Nabeshima,Norio Ozaki,Kiyofumi Yamada.
- Organizer
  6th Congress of AsCNP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] Specific MHCI overexpression in astrocytes induces behavioral and neuropathological abnormalities in mice2018
- Author(s)
  Kazuhiro Hada,Akira Sobue,Bolati Wulaer,Norimichi Itoh,Akira Nakajima,Takatoshi Nabeshima,Taku Nagai,Kiyofumi Yamada
- Organizer
  Society for Neuroscience 48th Annual Meeting(NEUROSCIENCE2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] 統合失調症モデル側坐核ニューロンの形態学的およびメタンフェタミン反応性の変化2018
- Author(s)
  羽田和弘、永井拓、伊藤教道、祖父江顕、Bolati Wulaer、森大輔、久島周、鍋島俊隆、尾崎紀夫、山田清文
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会合同年会
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] Acute methamphetamine administration impairs cognitive function in a touchscreen-based visual discrimination task in C57BL/6 mice.2018
- Author(s)
  Liao Jingzhu,Wulaer Bolati,Nagai Taku,Yamada Kiyofumi
- Organizer
  19th Congress of the International Society for Biomedical Research on Alcoholism (ISBRA2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] In vivo imaging for the effect of cocaine.2018
- Author(s)
  Youyun Zhu,Norimichi ito,Taku Nagai,Keisuke Kuroda,Kozo Kaibuchi,Toshitaka Nabeshima,Kiyofumi Yamada
- Organizer
  19th Congress of the International Society for Biomedical Research on Alcoholism (ISBRA2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] An operant task for testing risky decision-making in mice.2018
- Author(s)
  Tian Wang,Kazuya Fukumoto,Hiroyuki Mizoguchi,Kiyofumi Yamada
- Organizer
  19th Congress of the International Society for Biomedical Research on Alcoholism (ISBRA2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] The pathophusiological role of astroglial MHCI following systemic immune activation2018
- Author(s)
  Akira Sobue,NorimichiIto,Kazuhiro Hada,Akira Nakajima,Murakami Yuki,Mouri Akihiro,Yamamoto Yasuko,Toshitaka Nabeshima,Kuniaki Saito,Taku Nagai,Kiyofumi Yamada
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] Behavioral alterations accompanied by neuropathological changes induced by he expression of MHCI in the prefrontal cortex of mice.2017
- Author(s)
  Akira Sobue, Norimichi Ito, Kazuhiro Hada, Akira Nakajima, Toshitaka Nabeshima, Taku Nagai, Kiyofumi Yamada
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PUBLICLY-15H01284
[Presentation] Disruption of exons 2 and 3 of the Disc1 gene in the mouse is associated with elevated repetitive behavior.2017
- Author(s)
  Bolati Wulaer, Taku Nagai, Keisuke Kuroda, Kozo Kaibuchi, Toshitaka Nabeshima, Kiyofumi Yamada.
- Organizer
  5th Congress Of Asian College of Neuropsychopharmacology, AsCNP2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] 11.IFITM3 regulates polyI:C-induced neuronal impairment through RabGDI.2017
- Author(s)
  Norimichi Itoh, Taku Nagai, Daisuke Ibi, Akira Nakajima, Toshitaka Nabeshima, Kiyofumi Yamada.
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16K15201
[Presentation] Cognitive deficit correlated with changes in neuronal activity in Disc1 mice in touchscreen-based visual discrimination task.2017
- Author(s)
  Bolati Wulaer, Taku Nagai, Akira Sobue, Norimichi Itoh, Keisuke Kuroda, Kozo Kaibuchi, Toshitaka Nabeshima, Kiyofumi Yamada.
- Organizer
  NEUROSCIENCE2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] タッチパネル式視覚弁別試験を用いた精神疾患モデルマウスの認知機能解析2017
- Author(s)
  山田清文
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] 1.PolyIC model of schizophrenia:a role of IFITM3 in the neurodevelopmental impairment.2017
- Author(s)
  Kiyofumi Yamada
- Organizer
  5th Congress Of Asian College of Neuropsychopharmacology, AsCNP2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15201
[Presentation] Impaired visual discrimination learning in Disc1-knockout mice,reversed by clozapine treatment.2017
- Author(s)
  Bolati Wulaer, Taku Nagai, Akira Sobue, Keisuke Kuroda, Kozo Kaibuchi, Toshitaka Nabeshima, Kiyofumi Yamada.
- Organizer
  IBNS2017Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04031
[Presentation] 薬物依存症における意思決定異常2016
- Author(s)
  溝口博之、山田清文.
- Organizer
  第46回日本神経精神薬理学会
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] 島皮質GABA神経は薬物依存ラットの意思決定に関与する2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第39回日本神経科学会
- Place of Presentation
  パシフィコ横浜（横浜市西区）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Expression of MHCI in astrocytes impairs sociability and cognition2016
- Author(s)
  Sobue　A, Ito　N, Hada　K, Nakajima　A, Nagai　T, Nabeshima　T, Yamada　K
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PUBLICLY-15H01284
[Presentation] A strategy for treating in deficits of social behaviors induced by exposure to social defeat stress as juveniles.2016
- Author(s)
  Sho Hasegawa, Yuriko Miyake, Akira Yoshimi, Hirotake Hida, Akihiro Mouri, Kiyofumi Yamada, Norio Ozaki, Toshitaka Nabeshima, Yukihiro Noda:
- Organizer
  30th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  COEX(大韓民国)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460240
[Presentation] IFITM3による細胞内輸送系の制御機構2016
- Author(s)
  伊藤教道、永井拓、中島晶、衣斐大祐、山田清文
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26670121
[Presentation] Social defeat stress as juveniles impairs persistent social behaviors and neurogenesis.2016
- Author(s)
  Yukihiro Noda, Akihiro Mouri, Akira Yoshimi, Sho Hasegawa, Takahiro Ito, Hirotake Hida, Kiyofumi Yamada, Toshitaka Nabeshima, Norio Ozaki:
- Organizer
  30th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  COEX(大韓民国)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460240
[Presentation] 意思決定障害と創薬標的としてのニコチン受容体2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第18回応用薬理シンポジウム
- Place of Presentation
  名古屋大学（愛知県名古屋市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Nicotinic acetylcholine receptor as a target of harm reduction and treatment in addiction.2016
- Author(s)
  溝口博之、山田清文
- Organizer
  第５１回日本アルコール・アディクション医学会学術総会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Nicotine receptor as a potential target for treatment of pathological decision-making in addiction2015
- Author(s)
  Hiroyuki Mizoguchi, Kiyofumi Yamada.
- Organizer
  WPAIC 2015, 4th Asian Congress of Schizophrenia Research, 4th Congress of Asian College of Neuropsychopharmacology
- Place of Presentation
  Taipei、Taiwan
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] The insular GABAergic system controls decision-making in healthy and drug-dependent animals2015
- Author(s)
  Hiroyuki Mizoguchi, Kiyofumi Yamada
- Organizer
  IBNS 24th Annual Meeting
- Place of Presentation
  Victoria, Canada
- Year and Date
  2015-06-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Effect of nicotine on altered decision-making in methamphetamine-treated rat2015
- Author(s)
  Mizoguchi H, Wang T, Yamada K.
- Organizer
  International Symposium on Prediction and Decision Making 2015
- Place of Presentation
  東京
- Year and Date
  2015-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 基礎研究から探る薬物依存者の意思決定：リスク回避より目先の利益を優先する近視眼的意思決定2015
- Author(s)
  溝口博之、山田清文
- Organizer
  平成27年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  神戸
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Nicotine receptor as a potential target for treatment of pathological decision-making in addiction2015
- Author(s)
  Mizoguchi H, Yamada K.
- Organizer
  WPAIC 2015, 4th Asian Congress of Schizophrenia Research, 4th Congress of Asian College of Neuropsychopharmacology
- Place of Presentation
  Taipei
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Nucleus accumbens plays a role in arm choice behavior in the rodent gambling test2015
- Author(s)
  Mizoguchi H, Inutsuka A, Hikida T, Yamanaka A, Yamada K.
- Organizer
  2015年包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-12-17
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] The insular GABAergic system controls decision-making in healthy and drug-dependent animals.2015
- Author(s)
  Mizoguchi H, Yamada K.
- Organizer
  IBNS 24th Annual Meeting
- Place of Presentation
  Victoria
- Year and Date
  2015-06-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 基礎研究から探る薬物依存者の意思決定：リスク回避より目先の利益を優先する近視眼的意思決定2015
- Author(s)
  溝口博之、山田清文
- Organizer
  平成27年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  神戸国際会議場（神戸市中央区）
- Year and Date
  2015-10-11
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] 幼若期社会的敗北ストレス負荷マウスにおける社会性行動と神経発達への影響：グルココルチコイドの関与2014
- Author(s)
  野田幸裕、谷口将之、鵜飼麻由、毛利彰宏、肥田裕丈、長谷川章、森健太郎、山田清文、尾崎紀夫、鍋島俊隆
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良県奈良市
- Year and Date
  2014-09-29
- Data Source
  KAKENHI-PROJECT-26460240
[Presentation] IQGAP1の神経細胞における機能解折2014
- Author(s)
  伊藤教道、渡辺崇、永井拓、貝淵弘三、山田清文
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県和歌山市　和歌山県ＪＡビル
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] 精神疾患の病因仮説モデルを用いた創薬標的の探索研究2014
- Author(s)
  山田清文
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] IQGAP1の神経細胞における機能解折2014
- Author(s)
  伊藤教道、渡辺崇、永井拓、貝淵弘三、山田清文
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県和歌山市　和歌山県ＪＡビル
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-26670121
[Presentation] Serotonin transporter ubiquitynation is a potential biomarker for major depressive disorder2014
- Author(s)
  Nabeshima T, Mouri A, Yokoyama M, Kawano N, Yoshimi A , Ikeda M, Mamiya T, Yamada K, Iwata N, Ozaki N, Noda Y.
- Organizer
  29th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-24
- Data Source
  KAKENHI-PROJECT-26460240
[Presentation] Behavioral analysis in Reelin Orleans mice.2013
- Author(s)
  Taku Nagai, Wei Shan, Md.Ali-Bin-Saifullah, Daisuke Ibi, Kiyofumi Yamada
- Organizer
  11th World Congress of Biological Psychiatry
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] Effects of Short- and Long-Term Exposure to 1-Bromopropane on Neurogenesis in Adult Rats2013
- Author(s)
  L. Zhang, T. Nagai, K. Yamada, D. Ibi, S. Ichihara, K. Subramanian, Z. Huang,S. Sheik Mohideen, H. Naito, G. Ichihara
- Place of Presentation
  SanAntonio,USA
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] 1BP亜急性および慢性吸入曝露によるラット脳での神経新生への影響2013
- Author(s)
  張霊逸,永井拓,山田清文,衣斐大祐市原佐保子,スブラマニアンカビアラサン,黄振烈,シェイクモヒディーンサハブディン,内藤久雄,市原学
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢市（金沢大学　鶴間・宝町キャンパス）
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] 脳特異的転写因子Npas4欠損マウスにおける異常行為とGABA作動性神経系ﾏｰｶｰの変化2013
- Author(s)
  日比陽子、横井順平、永井拓、山田清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  ウィンクあいち（名古屋）
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via glucocorticoid receptor in the brain2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  11th WFSBP
- Place of Presentation
  京都市　京都国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via glucocorticoid receptor in the brain2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  11th WFSBP
- Place of Presentation
  京都府京都市京都国際会館
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Brain Dysfunction induced by chronic stress in early life: Invovement of the stress-sensitive transcripton factor Npas4.2013
- Author(s)
  Kiyofumi Yamada
- Organizer
  International Behavioral Neuroscience Society Annual Meeting2013
- Place of Presentation
  Dublin（Ireland）
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] Decision making in methamphetamine-treated rat.2013
- Author(s)
  H. Mizoguchi, K. Fukumoto, T. Wang, J. Sato, K. Yamada
- Organizer
  The 22rd Annual Meeting of International Behavioral Neuroscience Society
- Place of Presentation
  ダブリン
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 学習記憶形成におけるリン酸化Girdinの役割2013
- Author(s)
  永井拓、中井剛、田中基樹、浅井直也、榎本篤、曽我部正博、高橋雅英、山田清文
- Organizer
  第23回日本臨床精神神経薬理学会第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄コンベンションセンター（沖縄）
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] 脳特異的転写因子Npas4欠損マウスにおける異常行動とGABA作動性神経系マーカーの変化2013
- Author(s)
  日比(古川)陽子, 横井順平, 永井拓, 山田清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Year and Date
  2013-07-12
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Neuronal mechanism of impaired decision-making in an animal model of methamphetamine dependence.2013
- Author(s)
  H. Mizoguchi, K. Yamada
- Organizer
  International symposium of “Prediction and Decision Making” 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via glucocorticoid receptor in the brain.2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  11th World Congress of Biological Psychiatry
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] グルココルチコイド受容体は神経分化関連因子NPAS4の転写を直接抑制するDirect transcriptional regulation of neuronal transcription factor Npas4 by glucocorticoid receptor2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡県博多市福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] グルココルチコイド受容体は神経分化関連因子NPAS4の転写を直接抑制する Direct transcriptional regulation of neuronal transcription factor Npas4 by glucocorticoid receptor2013
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 新生仔期PolyI:C処置マウスの異常行動に対する抗精神病薬の効果とプロデオーム解析2013
- Author(s)
  永井拓、千崎康司、Yu Jinhua, 山田清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  ウィンクあいち（名古屋）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] 長期ストレスはGABA神経関連転写因子Npas4遺伝子のDNAメチル化を亢進する Chronic stress increases DNA methylation of Neuronal PAS domain 4 (Npas4)2013
- Author(s)
  日比（古川）　陽子、永井　拓、山田　清文
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  宜野湾市　沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Behavioral analysis in Reelin Orleans mice.2013
- Author(s)
  Taku Nagai, Wei Shan, Md.Ali-Bin-Saifullah, Daisuke Ibi, Kiyofumi Yamada
- Organizer
  11th World Congress of Biological Psychiatry
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] 長期ストレスはGABA神経関連転写因子Npas4遺伝子のDNAメチル化を亢進するChronic stress increases DNA methylation of Neuronal PAS domain 4 (Npas4)2013
- Author(s)
  日比(古川)陽子, 永井拓, 山田清文
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄県宜野湾市沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 転写因子Npas4によるﾏｳｽ嗅球新生介在ニューロンの感覚入力依存的なスパイン形成機構2013
- Author(s)
  吉原誠一、高橋弘雄、木下雅仁、西村信城、永井拓、山田清文、坪井昭夫
- Organizer
  Neuro2013
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] ラットにおける1-BPの亜急性と亜慢性吸入暴露によって神経新生への影響2013
- Author(s)
  張霊逸、永井拓、山田清文、衣斐大祐、市原佐保子、サブラマニアンカビアラサン、黄振烈、モヒデインサハブディン、内藤久雄、市原学
- Organizer
  第86回日本産業衛生学会
- Place of Presentation
  ひめぎんホール、愛媛・松山市
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] アストロサイト分泌因子Follistatin like-1の自然免疫活性化による神経発達障害への関与2013
- Author(s)
  山田真之亮、永井拓、衣斐大祐、山田清文
- Organizer
  Neuro2013
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] GirdinはNMDA受容体の関与により神経可塑性に重要な役割を果たす2013
- Author(s)
  中井剛、永井拓、田中基樹、浅井直也、榎本篤、曽我部正博、高橋雅英、山田清文
- Organizer
  Neuro2013
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] Altered emotional behavior and dopaminergic functions of Reelin Orleans mice.2013
- Author(s)
  Wei Shan, Taku Nagai, Umi Fukaya, Md.Ali-Bin-Saifullah, Kiyofumi Yamada
- Organizer
  AsCNP2013
- Place of Presentation
  Beijing(China)
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] Effects of sub-acute and sub-chronic inhalation exposure to 1-bromopropane　on neurogenesis in adult rats2013
- Author(s)
  Lingyi Zhang, Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara, Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen, Hisao Naito,Gaku Ichihara
- Organizer
  第12回分子予防環境医学研究会大会
- Place of Presentation
  つくばサイエンス・インフォメーションセンター（つくば市）
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] Effects of Short- and Long-Term Exposure to　1-Bromopropane on Neurogenesis in Adult　Rats.2013
- Author(s)
  L. Zhang, T. Nagai, K. Yamada, D. Ibi, S. Ichihara, K. Subramanian, Z. Huang, S. Sheik Mohideen, H. Naito, and G. Ichihara.
- Organizer
  The 52th Annual Meeting of the Society of Toxicology
- Place of Presentation
  SanAntonio,USA
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] Nicotine ameliorates emotional and cognitive impairments induced by neonatal polyI:C treatment in mice.2012
- Author(s)
  Taku Nagai, Jaesuk Yun, Daisuke Ibi, Toshitaka Nabeshima, Kiyofumi Yamada
- Organizer
  Neuroscience2012
- Place of Presentation
  New Orleans(USA)
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] Glucocorticoid reduces the gene expression of neuronal PAS domain 4 (Npas4) in the brain2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  ASCB2012
- Place of Presentation
  サンフランシスコ　USA
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Follistatin like-1 involves in polyI:C indeuced impairment of neurite outgrowth.(PolyI:Cによる神経突起伸展の障害におけるFollistatin like-1の関与）2012
- Author(s)
  山田真之介、永井拓、衣斐大祐、山田清文
- Organizer
  第22回日本臨床精神神経薬理学会第42回日本神経精神薬理学会合同年会
- Place of Presentation
  栃木総合文化センター（栃木）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] Glucocorticoid reduces the gene expression of neuronal PAS domain 4 (Npas4) in the brain2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  ASCB2012
- Place of Presentation
  USAサンフランシスコ
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation]2012
- Author(s)
  溝口博之、山田清文
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation]2012
- Author(s)
  Mizoguchi H, Yamada K
- Organizer
  2012 ISBRA World congress
- Place of Presentation
  札幌札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  The 11th APSN,The 55th J SN(日本神経化学会)
- Place of Presentation
  兵庫県神戸市神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation]2012
- Author(s)
  山田清文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Stress regulates the gene expression of neuronal PAS domain 4 (Npas4), via glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  CINP 2012
- Place of Presentation
  スウェーデンストックホルム
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation]2012
- Author(s)
  山田清文、溝口博之
- Organizer
  平成 24 年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  札幌札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation] グルココルチコイドによる転写因子NPAS4の発現抑制機構Glucocorticoid regulates the expression of neuronal PAS domain 4 (Npas4)2012
- Author(s)
  日比陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第7回統合失調症学会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Role of Astroglial IFITM3 in the neurodevelopmental impairments following neonatal polyIC treatment.2012
- Author(s)
  Nagai Taku, Ibi Daisuke, Nabeshima Toshitaka, Yamada Kiyofumi
- Organizer
  BRC Int'l Conference2012
- Place of Presentation
  Jeju（Korea）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] ラット脳内モノアミンレベルと海馬神経栄養因子の発現への1-ブロモプロパン曝露の影響2012
- Author(s)
  張霊逸,永井拓,山田清文,市原佐保子,スブラマニアンカビアラサン,黄振烈,シェイクモヒディーンサハブディーン,内藤久雄,市原学
- Organizer
  第85回日本産業衛生学会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] Exposure to 1-bromopropane decreases neuron proliferation in adult rat dentate gyrus2012
- Author(s)
  Lingyi ZHANG, Taku NAGAI, Kiyofumi YAMADA, Sahoko ICHIHARA, Kaviarasan SUBURAMANIAN, Zhenlie HUANG, Sahabudeen Sheik MOHIDEEN, Hisao NAITO, Gaku ICHIHARA
- Organizer
  The 6th International Congress of Asian Society of Toxicology
- Place of Presentation
  仙台国際センター（仙台市）
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] Stress regulates the gene expression of neuronal PAS domain 4 (Npas4), via glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  CINP 2012
- Place of Presentation
  ストックホルム　スウェーデン
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Stress regulates the gene expression of neuronal transcription factor Npas4 via glucocorticoid2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  第４回GCOE国際シンポジウム
- Place of Presentation
  名古屋キャッスルホテル（愛知）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ブチリルコリンエステラーゼ阻害剤のアミロイドベータ誘発性認知機能障害改善効果Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice2012
- Author(s)
  日比(古川)陽子, アルカム・トルソン, 新田淳美, 松山明裕, 永井拓, 山田清文
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府京都市京都国際会館
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation]2012
- Author(s)
  Yamada K, Ibi D, Nakajima A, Yamada S, Mizoguchi H, Nabeshima T and Nagai T
- Organizer
  8thFENS Forum of Neuroscience
- Place of Presentation
  Barcelona International Convention Center
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Stress regulates the gene expression of neuronal transcription factor Npas4 via glucocorticoid2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  第4回GCOE国際シンポジウム
- Place of Presentation
  愛知県名古屋市ウエスティンナゴヤキャッスルホテル
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Animal model of treatment-resistant schizophrenia.2012
- Author(s)
  Kiyofumi Yamada, Daisuke Ibi, Akira Sawa, Taku Nagai
- Organizer
  28th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  Stockholm（Sweden）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] Astroglial IFITM3 contributes to the neurodevelopmenetal impairment by neonatal polyI:C treatment in mice.2012
- Author(s)
  Yamada Kiyofumi,　Ibi　Daisuke,　Nakajima　Akira,　Yamada　Shinnosuke,　Mizoguchi　Hiroyuki,　Nabeshima　Toshitaka,　Nagai Taku
- Organizer
  8th FENS Forum of Neuroscience
- Place of Presentation
  Barcelona（ Spain）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] Behavioral and neurochemical alterations associated with targeted disruption of exons 2 and 3 of the DISC1 gene in the mouse.2012
- Author(s)
  山田清文
- Organizer
  第34回日本生物学的精神医学会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PUBLICLY-24111518
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by glucocorticoid receptor2012
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, and Kiyofumi Yamada
- Organizer
  The 11th APSN The 55th JSN（日本神経化学会）
- Place of Presentation
  神戸国際会議場（兵庫）
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Effects of short- and long-term exposure to 1-bromopropane on neurogenesis in adult　rats.2012
- Author(s)
  Lingyi Zhang,Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara,Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen,Hisao Naito, and Gaku Ichihara
- Organizer
  日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
- Place of Presentation
  マホロバマインズ三浦、神奈川
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] 内因性薬物依存修飾因子2011
- Author(s)
  山田清文
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] 神経発達関連転写因子NPAS4のストレスによる転写抑制機構の解明2011
- Author(s)
  日比(古川)陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  愛知県名古屋市愛知県産業労働センター
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation]2011
- Author(s)
  Yamada K.
- Organizer
  Society of Biological Psychiatry 66thAnnual Scientific Meeting & Convention
- Place of Presentation
  San Francisco Hyatt Regency, Embarcadero Center
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Neuronal Mechanisms of methamphetamine-seeing Behaviour2011
- Author(s)
  Kiyofumi Yamada
- Organizer
  5^<th> CINP Pacific-Asia Regional Meeting
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Stress reduces the expression of transcription factor, neuronal PAS domain 4 (NPAS4)2011
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  AsCNP2011
- Place of Presentation
  韓国ソウル市
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] ストレスによるneuronal PAS domain 4 (NPAS4)の転写制御Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by stress2011
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 神経発達関連転写因子NPAS4の発現調節機構の解明2011
- Author(s)
  日比(古川)陽子, ユンジェスク, 永井拓, 山田清文
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 脳神経発達障害の行動学的解析;周産期疑似ウィルス感染モデルを例として2011
- Author(s)
  山田清文
- Organizer
  第23回産業神経・行動学研究会
- Place of Presentation
  名古屋大学(愛知県)(招待講演)
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Role of IFITM3 in Polyl : C-induced Brain Dysfunction : Implication in Neurodevelopmental Disorders2011
- Author(s)
  Kiyofumi Yamada
- Organizer
  Society of Biological Psychiatry 66^<th> Annual Scientific Meeting & Convention
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Nicotinic Receptors ; A Potential Drug Target for Treatment of Cognitive Impairments Associated with Methamphetamine Dependence2011
- Author(s)
  Kiyofumi Yamada
- Organizer
  2th Congress of AsCNP
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation]2010
- Author(s)
  衣斐大祐、永井拓、中島晶、鍋島俊隆、山田清文
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台仙台国際センター
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] 新生仔期polyI : C処置によって誘発される不安様行動および学習記憶障害に対するニコチンの効果2010
- Author(s)
  山田清文, 他
- Organizer
  第117回日本薬理学会近畿部会
- Place of Presentation
  徳島
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] PolyI : C誘発性神経発達障害モデル:結合失調症動物モデルとしての有用性と発症機構2010
- Author(s)
  山田清文, 他
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22390046
[Presentation] Pharmacologic treatment with GABA_B receptor agonist on methamphetamine-induced cognitive impairment in mice2009
- Author(s)
  山田清文, et al.
- Organizer
  International Drug Abuse Research Society
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Influence of chronic restraint stress on hippocampal neurogenesis and hippocampus-dependent fear memory in mice.2009
- Author(s)
  山田清文, et al.
- Organizer
  Society for Neuroscience 2009.
- Place of Presentation
  Chicago, USA.
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Poly : C誘発神経発達障害動物モデルの行動異常とその発現機構2009
- Author(s)
  山田清文
- Organizer
  愛知県心身障害者コロニー発達障害研究所公開シンポジウム2009「自閉症・発達障害の基礎と臨床」
- Place of Presentation
  愛知県春日井市
- Year and Date
  2009-12-18
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Influence of chronic restraint stress on hippocampal neurogenesis and hippocampus-dependent fear memory in mice2009
- Author(s)
  山田清文, et al.
- Organizer
  Society for Neuroscience2009
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 神経発達障害仮説に基づく精神疾患動物モデル2009
- Author(s)
  山田清文
- Organizer
  金沢大学創基150年記念「講演会・シンポジウム」シリーズ第2回「社会性認識」学際脳科学シンポジウム
- Place of Presentation
  石川県金沢市
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Perinatal immune activation impairs emotional and cognitive functions with altered hippocampal glutamatergic neurotransmission in adult mice2009
- Author(s)
  山田清文, et al.
- Organizer
  9th World Congress of Biological Psychiatry
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Perinatal immune activation impairs emotional and cognitive functions with altered hippocampal glutamatergic neurotransmission in adult mice.2009
- Author(s)
  山田清文, et al.
- Organizer
  9th World Congress of Biological Psychiatry.
- Place of Presentation
  Paris, France.
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Early life stress-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice. (Symposium I)2008
- Author(s)
  Yamada K
- Organizer
  International Symposium on Brain Development and Neuropsvchiatric Disorders
- Place of Presentation
  名古屋
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 薬物依存に関与するサイトカイン・プロテアーゼの動態および機能解析.2008
- Author(s)
  山田清文
- Organizer
  第45回脳の医学・生物学研究会
- Place of Presentation
  名古屋
- Year and Date
  2008-08-02
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 遺伝子変異マウスを用いた薬物依存モデルの行動解析. (シンポジウム「精神疾患とその病態モデル小動物の表現型解析」)2008
- Author(s)
  山田清文, 他
- Organizer
  第55回日本実験動物学会総会, 第42回日本実験動物技術者協会総会合同大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] GABAB receptor agonist baclofen improves cognitive deficit induced by repeated methamphetamine treatment in mice.2008
- Author(s)
  Yamada K, et al.
- Organizer
  38th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Washington, D. C., U.S.A.
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] tPA-プラスミンシステムによるニコチンの報酬効果の制御:PAR-1の関与.(シンポジウム「プロテイナーゼ活性化型受容体の基礎と臨床:新たな治療標的としての可能性を探る」)2008
- Author(s)
  山田清文
- Organizer
  第81回日本薬理学会年会.
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] メタンフェタミン依存マウスにおける薬物探索行動 : GDNFの役割. (シンポジウム2「動物やヒトの行動に対する遺伝子・環境相互作用」)2008
- Author(s)
  山田清文, 他
- Organizer
  第51回日本神経化学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Alterations of Adult Neurogenesis in Animal Models for Schizophrenia : Role for NMDA Receptors. (Joint symposium with JSN "NMDA Receptor and Molecular Pathology of Schizophrenia")2008
- Author(s)
  Yamada K
- Organizer
  2nd WFSBP Asia-Pacific Congress and 30th Annual Meeting of JSBP
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 覚せい剤による依存・精神病性障害と認知機能障害における組織プラスミノーゲン活性化因子の関与.(シンポジウム「アルコール・薬物依存の基礎研究の動向」)2007
- Author(s)
  山田清文, 他
- Organizer
  第42回日本アルコール・薬物医学会, 第19回日本アルコール精神医学会, 第10回ニコチン・薬物依存研究フォーラム平成19年度合同学術総会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] 覚せい剤による依存・精神病性障害と認知機能障害における組織プラスミノーゲン活性化因子の関与(シンポジウム「アルコール・薬物依存の基礎研究の動向」).2007
- Author(s)
  山田清文, 永井拓, 溝口博之, 鍋島俊隆, 田熊一敞
- Organizer
  第42回日本アルコール・薬物医学会, 第19回日本アルコール精神医学会, 第10回ニコチン・薬物依存研究フォーラム平成19年度合同学術総会.
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] The role of tissue plasminogen activator in methamphetamine-induced reward, behavioral sensitization and cognitive deficit in mice.2007
- Author(s)
  Yamada K, et. al.
- Organizer
  2007 Symposium of the Institute of Pharmaceutical Science (Kangwon National Univ.) & The Korean Association of Drug Abuse-A Memorial Event for the 60th Anniversary of Founding of Kangwon National University
- Place of Presentation
  Chunchon, Korea
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19390062
[Presentation] Neuronal mechanisms of methamphetamine-seeking behavior in mice
- Author(s)
  Yamada K, Yan Y, Nitta A, Mizoguchi H, Nabeshima T
- Organizer
  5th CINP Pacific-Asia Regional Meeting 2011
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation] Matrix metalloproteinase-3とpolyI:C誘発性自然免疫活性化により惹起される神経発達障害
- Author(s)
  永井拓、山田真之亮、山田清文
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] 覚せい剤依存モデル動物の近視眼的意思決定と島皮質障害.
- Author(s)
  溝口博之、福本和哉、山田清文
- Organizer
  平成25年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 島皮質は薬物依存症モデルラットの意思決定に関与する
- Author(s)
  溝口博之、山田清文
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 神経発達関連転写因子NPAS4の発現調節機構の解明
- Author(s)
  日比（古川）陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 内因性薬物依存修飾因子
- Author(s)
  山田清文
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation] Dysfunction of GABAergic system in the insular cortex is associated with impaired decision-making in methamphetamine-treated rats
- Author(s)
  Yamada K., Fukumoto K., Wang T., Mizoguchi H.
- Organizer
  29th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  バンクーバー
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 薬物依存症の意思決定異常と島皮質
- Author(s)
  溝口博之、片平健太郎、犬束　歩、大平英樹、山中章弘、山田清文
- Organizer
  第36回日本生物学的精神医学会、第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] 脳特異的転写因子Npas4欠損マウスにおける異常行動とGABA作動性神経系マーカーの変化
- Author(s)
  日比（古川）　陽子、横井　順平、永井　拓、山田　清文
- Organizer
  第123回日本薬理学会近畿部会
- Place of Presentation
  名古屋市　ウインク愛知
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Dysfunction of GABA ergic system in the insular cortex is associated with impaired decision-making in methamphetamine-treated rats.
- Author(s)
  Yamada K, Fukumoto K, Wang T, Mizoguchi H
- Organizer
  29th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  バンクーバー（カナダ）
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] グルココルチコイドによる転写因子NPAS4の発現抑制機構 Glucocorticoid regulates the expression of neuronal PAS domain 4 (Npas4).
- Author(s)
  日比　陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第7回統合失調症学会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Npas4 regulates neurite outgrowth and phosphoryation of synapsin I
- Author(s)
  Jaesuk Yun, Taku Nagai, Yoko Hibi, Keisuke Kuroda, Kozo Kaibuchi, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Reward-Based Decision-making in methamphetamine-dependent rat.
- Author(s)
  Mizoguchi H., Fukumoto K., Wang T., Yamada K.
- Organizer
  9th Federation of European Neuroscience Societies, Forum of Neuroscience
- Place of Presentation
  ミラノ
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] Effects of sub-acute and sub-chronic inhalation exposure to 1-bromopropane on neurogenesis in adult rats.
- Author(s)
  Lingyi Zhang, Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara, Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen, Hisao Naito, Gaku Ichihara
- Organizer
  日本産業衛生学会　産業神経・行動学研究会　第24回研究会
- Place of Presentation
  東京女子医科大学医学部中央校舎5階（東京）
- Data Source
  KAKENHI-PROJECT-23659326
[Presentation] Dysfunction of gabaergic system in the insular cortex contributes to impairments of decision-making in methamphetamine-depandent rats.
- Author(s)
  Yamada K, Mizoguchi H
- Organizer
  ISAM2014
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Year and Date
  2014-10-02 – 2014-10-06
- Data Source
  KAKENHI-PROJECT-26293053
[Presentation] Methamphetamine-induced Npas4; possible role in neurite outgrowth and p-synapsin I expression
- Author(s)
  Yun Jaesuk, Nagai Taku, Hibi Yoko, Kuroda Keisuke, Kaibuchi Kozo,Yamada Kiyofumi
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] リン酸化GirdinはNMDA受容体を介して神経可塑性を制御する
- Author(s)
  永井拓、中井剛、田中基樹、浅井直也、榎本篤、曽我部正博、高橋雅英、山田清文
- Organizer
  第24回日本臨床精神神経薬理学会・第44回日本神経精神薬理学会
- Place of Presentation
  愛知県名古屋市　名古屋国際会議場
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] リン酸化GirdinはNMDA受容体を介して神経可塑性を制御する
- Author(s)
  永井拓、中井剛、田中基樹、浅井直也、榎本篤、曽我部正博、高橋雅英、山田清文
- Organizer
  第24回日本臨床精神神経薬理学会・第44回日本神経精神薬理学会
- Place of Presentation
  愛知県名古屋市　名古屋国際会議場
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26670121
[Presentation] 神経発達関連転写因子NPAS4のストレスによる転写抑制機構の解明
- Author(s)
  日比（古川）陽子、ユン　ジェスク、永井　拓、山田　清文
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋　愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by stress ストレスによるneuronal PAS domain 4 (NPAS4)の転写制御
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai, Kiyofumi Yamada
- Organizer
  Neuroscience 2011
- Place of Presentation
  横浜　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] DERADDシステムで報酬に基づく意思決定行動を操作する.
- Author(s)
  溝口博之、福本和哉、犬束歩、山中章弘、山田清文
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] マトリックスメタロプロテアーゼはpolyI:C誘発性自然免疫活性化により惹起される神経発達障害を仲介する
- Author(s)
  永井拓、山田真之亮、山田清文
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本県熊本市　熊本大学
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-26670121
[Presentation] The Role of Npas4 in Neurite Outgrowth and phosphorylation of Synapsin I
- Author(s)
  Jaesuk Yun, Taku Nagai, Yoko Hibi, Keisuke Kuroda, Kozo Kaibuchi, Kiyofumi Yamada
- Organizer
  AsCNP
- Place of Presentation
  韓国　ソウル
- Data Source
  KAKENHI-PROJECT-23590299
[Presentation] 覚せい剤依存症モデルラットの意思決定障害と島皮質
- Author(s)
  溝口博之、福本和哉、山田清文
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460094
[Presentation] マトリックスメタロプロテアーゼはpolyI:C誘発性自然免疫活性化により惹起される神経発達障害を仲介する
- Author(s)
  永井拓、山田真之亮、山田清文
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本県熊本市　熊本大学
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PUBLICLY-25116515
[Presentation] 報酬に基づく意思決定機構に対する覚せい剤の効果
- Author(s)
  溝口博之、佐藤純、山田清文
- Organizer
  平成23年度アルコール・薬物依存関連学会合同学術総会
- Place of Presentation
  名古屋、愛知県産業労働センター
- Data Source
  KAKENHI-PROJECT-23659135
[Presentation] Matrix metalloproteinase-3とpolyI:C誘発性自然免疫活性化により惹起される神経発達障害
- Author(s)
  永井拓、山田真之亮、山田清文
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26670121
[Presentation] Stress reduces the expression of transcription factor, neuronal PAS domain 4 (NPAS4)
- Author(s)
  Yoko Hibi, Jaesuk Yun, Taku Nagai and Kiyofumi Yamada
- Organizer
  AsCNP
- Place of Presentation
  韓国　ソウル
- Data Source
  KAKENHI-PROJECT-23590299
[]

1. NAGAI Taku (10377426)

# of Collaborated Projects: 9 results

# of Collaborated Products: 71 results
2. MIZOGUCHI Hiroyuki (70402568)

# of Collaborated Projects: 8 results

# of Collaborated Products: 61 results
3. NABESHIMA Toshitaka (70076751)

# of Collaborated Projects: 7 results

# of Collaborated Products: 37 results
4. TAKUMA Kazuhiro (90289025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. HIBI Yoko (70295616)

# of Collaborated Projects: 3 results

# of Collaborated Products: 48 results
6. NTTTA Atsumi (20275093)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. ITOH Norimichi (30726310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. HIRAMATSU Masayuki (10189863)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ICHIHARA Gaku (90252238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
10. ICHIHARA Sahoko (20378326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
11. SOKABE Masahiro (10093428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NAWA Hiroyuki (50183083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMANAKA Akihiro (60323292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. MOURI Akihiro (20597851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. YOSHIMI Akira (00637671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. MAMIYA Takayoshi (70340297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. OZAKI Norio (40281480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
18. KITAGAKI Shinji (20281818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 鍋島陽一 (60108024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 木村和子 (80324094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 辻彰 (10019664)

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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23. 清水栄 (10110545)

# of Collaborated Projects: 1 results

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24. 松下良 (20293368)

# of Collaborated Projects: 1 results

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25. 俵友恵 (40251962)

# of Collaborated Projects: 1 results

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26. 鈴木永雄 (50092250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 村松慎一 (10239543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 野田幸裕 (90397464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
29. 松崎哲郎 (80866450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
30. LING Chen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. HIDA Hirotake

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
32. HASEGAWA Sho

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
33. JEANーMARC Ka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. ISABELLE Cha

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. TANGUI Mauri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. ALAIN Privat

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. MURAKAMI Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. SOTOMATSU Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. TAKAO Kohno

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
40. TORIUMI Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. ENOMOTO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. DAISUKE Mori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. TANAKA Tetsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 林泰秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 黒田啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 浅井直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 高橋雅英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 及川伸二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 田中啓治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 山森哲雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 田中真樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 田中謙二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 阿部修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 森寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 祖父江顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 田中里奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 衣斐大祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMADA KIYOFUMI 山田 清文

YAMADA Kiyofumi 山田 清文

Research Projects

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Study on the regulation mechanism of neural spine morphology and cognitive function by twinfilin-1Principal Investigator

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Genomic analysis-based neuropharmacological study on basal ganglia-thalamocortical circuits for new drug discovery in schizophreniaPrincipal Investigator

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Development a translatable visual discrimination test in rodents to apply for drug discovery and developmentPrincipal Investigator

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Development of a new transgenic mouse model as a platform for the imaging-based drug discovery and developmentPrincipal Investigator

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グリア細胞におけるMHCクラスⅠ分子の過剰発現とマイクロエンドフェノタイプPrincipal Investigator

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Study on the neuronal circuit and molecular mechanis underlying decision-making and its application for drug developmentPrincipal Investigator

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Real-time imaging of the mechanism underlying neuroinflammation-induced neuropsychiatric disordersPrincipal Investigator

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ストレス応答性転写因子NPAS4欠損マウスにおけるGABA神経発達と表現型解析Principal Investigator

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アストログリア細胞のエンドサイトーシスの障害による神経発達障害Principal Investigator

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Effect of drugs of abuse on reward-based decision-making in rodentsPrincipal Investigator

YAMADA KIYOFUMI 山田清文

YAMADA Kiyofumi 山田清文