Suga Kei 須賀圭

… Alternative Names

須賀圭スガケイ

SUGA Kei 須賀圭

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Researcher Number	30306675
Other IDs
Affiliation (Current)	2025: 杏林大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 杏林大学, 医学部, 准教授 2018 – 2020: 杏林大学, 医学部, 講師 2013 – 2015: 杏林大学, 医学部, 講師 2007 – 2010: Kyorin University, 医学部, 助教 2004 – 2006: 杏林大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Basic Section 46010:Neuroscience-general-related / Neurochemistry/Neuropharmacology Except Principal Investigator Basic Section 38060:Applied molecular and cellular biology-related / Neurophysiology and muscle physiology / Anesthesiology/Resuscitation studies / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator syntaxin / SNARE / 脳・神経 / 神経科学 / vesicle transport / シンタキシン / 低分子化合物 / シャペロン / 神経細胞保護 / Syx5 … More / ゴルジストレス / Aベータペプチド / アルツハイマー病 / 神経変性疾患 / 細胞死 / オートファジー / アルツハイマー / ERストレス / Golgi / ER-stress / 脳神経疾患 / ストレス / amyloid β peptide / Alzheimer's disease / presenilin … More Except Principal Investigator syntaxin1A / syntaxin1B / 遺伝子ノックアウトマウス / シンタキシン1B / シンタキシン1A / シナプス伝達 / 相互作用分子 / 相互作用 / SPCA / Ca2+ポンプ / 乳がん / ノックアウトマウス / 神経成長因子 / 開口放出 / シンタキシン１B / haploid / 自閉性障害 / 遅い神経伝達物質放出過程 / 速い神経伝達物質放出過程 / シンタキシン１Ｂ / シンタキシン１A / BDNF / グリア細胞 / 機能分化 / 神経伝達 / MPT / グルタミン酸 / 神経細胞死 / 膜電位 / アポトーシス / 細胞死 / カルシウム / ミトコンドリア / 疾患モデル / 自閉症 / シンタキシン1 / 運動障害 / 痙攣発作 / 致死 / 遅い神経伝達 / 速い神経伝達 / 行動異常 / シナプス伝達制御因子 / シナプス機能分化 / 疾患モデル動物 / ノックアウトマウス自閉性障害 Less

Analysis of molecular mechanisms of breast cancer malignant progression focusing on a regulator of Ca2+ pump SPCA2.
- Principal Investigator
  
  山本幸子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Kyorin University
Regulation of Abeta secretion and protective mechanisms by Golgi stress responsive factor Syx5 and chemical compound in neuronal cellsPrincipal Investigator
- Principal Investigator
  
  Suga Kei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kyorin University
Role for ER stress responsive ER-Golgi SNARE in processing of Alzheimer`s disease-related protein and autophagyPrincipal Investigator
- Principal Investigator
  
  Suga Kei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
Functional difference between syntaxin1 isoforms in synaptic transmission
- Principal Investigator
  
  AKAGAWA kimio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kyorin University
Analysis of syntaxin 1 gene knockout mice as an animal model for autistic disorder
- Principal Investigator
  
  AKAGAWA Kimio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
Role of Syntaxin5 isoforms in neuronal cells under ER stressPrincipal Investigator
- Principal Investigator
  
  SUGA Kei
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
Brain protection through calcium buffering system in mitochondria
- Principal Investigator
  
  IIJIMA Takehiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyorin University
アルツハイマー病関連蛋白質の細胞内輸送におけるSyntaxinファミリーの役割Principal Investigator
- Principal Investigator
  
  須賀圭
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University

[Book] 生体の科学2004
- Author(s)
  須賀圭, 赤川公朗
- Total Pages
  1
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] Cytoplasmic control of Rab family small GTPases through BAG62019
- Author(s)
  Takahashi Toshiki、Minami Setsuya、Tsuchiya Yugo、Tajima Kazu、Sakai Natsumi、Suga Kei、Hisanaga Shin‐ichi、Ohbayashi Norihiko、Fukuda Mitsunori、Kawahara Hiroyuki
- Journal Title
  
  EMBO reports
  
  Volume: 20 Issue: 4
- DOI
  10.15252/embr.201846794
- NAID
  120007127921
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06468, KAKENHI-PUBLICLY-17H05682, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16K07060, KAKENHI-PROJECT-19K06653, KAKENHI-PUBLICLY-19H05293, KAKENHI-PROJECT-17H03657
[Journal Article] Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells2016
- Author(s)
  Ayako Saito, Kei Suga, Risa Ono-Nakagawa, Masumi Sanada, and Kimio Akagawa
- Journal Title
  
  Data in Brief
  
  Volume: 6 Pages: 20-27
- DOI
  10.1016/j.dib.2015.11.030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430072
[Journal Article] ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid beta peptide secretion.2015
- Author(s)
  K.Suga, A.Saitoh, and K.Akagawa
- Journal Title
  
  Ｅｘｐｅｒｉｍｅｎｔａｌ　ｃｅｌｌ　ｒｅｓｅａｒｃｈ
  
  Volume: 332 Pages: 11-23
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300142
[Journal Article] Data for the effects of ER and Golgi stresses on the ER-Golgi SNARE Syntaxin5 expression and on the βAPP processing in cultured hippocampal neurons2015
- Author(s)
  Kei Suga, Ayako Saito, Tatsuya Mishima, and Kimio Akagawa
- Journal Title
  
  Data in Brief
  
  Volume: 5 Pages: 114-123
- DOI
  10.1016/j.dib.2015.08.023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430072
[Journal Article] ER and Golgi stresses increase ER-Golgi SNARE Syntaxin5: Implications for organelle stress and βAPP processing2015
- Author(s)
  Kei Suga, Ayako Saito, Tatsuya Mishima, and Kimio Akagawa
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 604 Pages: 30-35
- DOI
  10.1016/j.neulet.2015.07.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430072
[Journal Article] Data supporting ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion2015
- Author(s)
  Kei Suga, Ayako Saito, and Kimio Akagawa
- Journal Title
  
  Data in Brief
  
  Volume: 5 Pages: 782-788
- DOI
  10.1016/j.dib.2015.10.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430072
[Journal Article] ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion2015
- Author(s)
  Kei Suga, Ayako Saito, and Kimio Akagawa
- Journal Title
  
  Exp.Cell Res.
  
  Volume: 332 Issue: 1 Pages: 11-23
- DOI
  10.1016/j.yexcr.2015.01.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430072
[Journal Article] FRET-based evaluation of Bid cleavage in a single primary cultured neuron.2013
- Author(s)
  Nakazawa H
- Journal Title
  
  Neurosci Lett.
  
  Volume: 536 Pages: 24-28
- DOI
  10.1016/j.neulet.2012.11.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591717, KAKENHI-PROJECT-25430072
[Journal Article] Up-regulation of Syntaxin5 protein expression under ER stress2010
- Author(s)
  K.Suga, A.Saito, T.Mishima, K.Akagawa
- Journal Title
  
  Bull.Jpn.Soc.Neurochem.
  
  Volume: 49(No.2,3) Pages: 631-631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] The syntaxin 5 isoforms Syx5 and Syx5L have distinct effects on the processing of s-amyloid precursor protein.2009
- Author(s)
  K. Suga, A. Saito, T. Tomiyama, H. Mori, K. Akagawa
- Journal Title
  
  J. Biochem Vol.146
  
  Pages: 905-915
- Data Source
  KAKENHI-PROJECT-19300133
[Journal Article] Y. Iwao Ca2+ buffering capacity of mitochondria after oxygen-glucose deprivation in hippocampal neurons.2009
- Author(s)
  K. Tanaka, T. Iijima, T. Mishima, K. Suga, K. Akagawa
- Journal Title
  
  Neurochem. Res Vol. 34
  
  Pages: 221-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] The Syntaxin5 isoforms Syx5 and Syx5L have distinct effects on the processing of・APP2009
- Author(s)
  K. Suga, A. Saito, T. Tomiyama, H. Mori, K. Akagawa
- Journal Title
  
  J.Biochem Vol.146, No.6
  
  Pages: 905-915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] The Syntaxin5 isoforms Syx5 and Syx5L have distinct effects on the processing of βAPP2009
- Author(s)
  K.Suga, A.Saito, T.Tomiyama, H.Mori, K.Akagawa
- Journal Title
  
  J.Biochem. 146, No.6
  
  Pages: 905-915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Ca^<2+> buffering capacity of mitochondria after oxygen-glucose deprivation in hippocampal neurons2009
- Author(s)
  K.Tanaka, T.Iijima, T.Mishima, K.Suga, K.Akagawa, Y.Iwao
- Journal Title
  
  Neurochem.Res. Vol.34
  
  Pages: 221-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] The Syntaxin 5 isoforms Syx5 and Syx5L have distinct effects on the processing of β-amyloid precursor protein.2009
- Author(s)
  K.Suga, et al.
- Journal Title
  
  J.Biochemistry 146
  
  Pages: 905-915
- NAID
  10026305531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300133
[Journal Article] Ca^<2+> buffering capacity of mitochondria after oxygen-glucose deprivation in hippocampal neurons2009
- Author(s)
  K. Tanaka, T. Iijima, T. Mishima, K. Suga, K. Akagawa, Y. Iwao
- Journal Title
  
  Neurochem. Res. 34
  
  Pages: 221-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] The Syntaxin5 isoforms Syx5 and Syx5L have distinct effects on the processing of βAPP2009
- Author(s)
  K.Suga, A.Saito, T.Tomiyama, H.Mori, K.Akagawa
- Journal Title
  
  J.Biochem. Vol.146, No.6
  
  Pages: 905-915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Role of Syntaxin5 isoforms on the processing and trafficking of βAPP in the ER through the Golgi compartments2009
- Author(s)
  K.Suga, A.Saito, T.Tomiyama, H.Mori, K.Akagawa
- Journal Title
  
  Bull.Jpn.Soc.Neurochem. 48(No.2,3)
  
  Pages: 193-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Y. Iwao Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model.2008
- Author(s)
  T. Iijima, K. Tanaka, S. Matsubara, S. Kawakami, T. Mishima, K. Suga, K. Akagawa
- Journal Title
  
  Neurosci. Lett Vol.448
  
  Pages: 268-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model2008
- Author(s)
  Iijima T, Tanaka K, Matsubara S, Kawakami H, Mishima T, Suga K, Akagawa K, Iwao Y
- Journal Title
  
  Neuroscience Lett 448(3)
  
  Pages: 268-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591818
[Journal Article] Syntaxin8 has two functionally disthinct di-leucine based motif2008
- Author(s)
  Kazuo Kasai, Kei Suga, Tetsuro Izumi, Kimio Akagawa
- Journal Title
  
  Cell. Mol. Biol. lett 13
  
  Pages: 144-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model2008
- Author(s)
  T.Iijima, K.Tanaka, S.Matsubara, S.Kawakami, T.Mishima, K.Suga, K.Akagawa, Y.Iwao
- Journal Title
  
  Neurosci.Lett. Vol.448
  
  Pages: 268-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Ca^<2+> buffering capacity of mitochondria after oxygen-glucose deprivation in hippocampal neurons2008
- Author(s)
  Tanaka K, Iijima T, Mishima T, Suga K, Akagawa K, Iwao Y
- Journal Title
  
  Neurochemical Research 34(2)
  
  Pages: 221-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591818
[Journal Article] Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model2008
- Author(s)
  Iiiima T, Tanaka K, Matsubara S, Kawakami H, Mishima T, Suga K, Akagawa K, Iwao K
- Journal Title
  
  Neurosci Letter 448(3)
  
  Pages: 268-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591818
[Journal Article] Iwao Y Ca^<2+> buffering capacity of mitochondria after oxygen-glucose deprivation in hippocampal neurons2008
- Author(s)
  Tanaka K, Iijima T, Mishima T, Suga K, Akagawa K
- Journal Title
  
  Neurochemical Research 34(2)
  
  Pages: 221-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591818
[Journal Article] Distinct effect of Syntaxin5 isoforms on the processing of βAPP2008
- Author(s)
  K. Suga, A. Saito, T. Tomiyama, H. Mori, K. Akagawa
- Journal Title
  
  Bull. Jpn. Soc. Neurochem. 47
  
  Pages: 253-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model.2008
- Author(s)
  T. Iijima, K. Tanaka, S. Matsubara, S. Kawakami, T. Mishima, K. Suga, K. Akagawa, Y. Iwao
- Journal Title
  
  Neurosci Lett. 448
  
  Pages: 268-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Syntaxin8 has two functionally distinct di-leucine based motif2008
- Author(s)
  K.Kasai, K.Suga, T.Izumi, K.Akagawa
- Journal Title
  
  Cell.Mol.Biol.lett. Vol.13
  
  Pages: 144-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Syntaxin8 has two functionally distinct di-leucine based motif.2008
- Author(s)
  K. Kasai, K. Suga, T. Izumi, K. Akagawa
- Journal Title
  
  Cell. Mol. Biol. lett Vol.13
  
  Pages: 144-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Effects of Syntaxin5 isoforms on the accumulation of intracellular βAPP and the secretion of Aβ peptides2007
- Author(s)
  Kei Suga, Ayako Saito, Takami Tomiyama, Hiroshi Mori and Kimio Akagawa
- Journal Title
  
  Bull. Jpn. Soc. Neurochem 46
  
  Pages: 484-484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500327
[Journal Article] Properties of Syntaxin5 isotorms in the interaction with presenilin holoproteins and processing of βAPP2006
- Author(s)
  Kei Suga, Ayako Saito, Takami Tomiyama, Hiroshi Mori, Kimio Akagawa
- Journal Title
  
  Bull. Jpn. Soc. Neurochem. 45
  
  Pages: 448-448
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] RNA interference-mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles2005
- Author(s)
  Kei Suga, Hiroshi Hattori, Ayako Saito, Kimio Akagawa
- Journal Title
  
  FEBS lett. 579
  
  Pages: 4226-4234
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] Syntaxin specificities in the interaction with presenilin holoproteins, the accumulation of intracellular βAPP, and the suppression of β-amyloid production2005
- Author(s)
  Kei Suga, Ayako Saito, Takami Tomiyama, Hiroshi Mori, Kimio Akagawa
- Journal Title
  
  Jpn.J.Physiol. 55(Suppl)
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] Syntaxin5 interacts specifically with presenilin holoproteins and affects processing of βAPP in neuronal cells2005
- Author(s)
  Kei Suga, Ayako Saito, Takami Tomiyama, Hiroshi Mori, Kimio Akagawa
- Journal Title
  
  Bull.Jpn.Soc.Neurochem. 44
  
  Pages: 203-203
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] Syntaxin 5 specifically interacts with presenilin holoproteins, and affects processing of βAPP in neuronal cells2005
- Author(s)
  Kei Suga, Ayako Saito, Takami Tomiyama, Hiroshi Mori, Kimio Akagawa
- Journal Title
  
  J.Neurochem. 94
  
  Pages: 425-439
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] Interaction between Presenilin holoproteins and Syntaxin isoforms2004
- Author(s)
  Kei Suga, Takami Tomiyama et al.
- Journal Title
  
  Jpn.J.Physiol. 54(Suppl)
- NAID
  130005447396
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] Syntaxin 5 interacts with Presenilin holoproteins and suppresses the production of Aβ peptides2004
- Author(s)
  Kei Suga, Takami Tomiyama et al.
- Journal Title
  
  Bull.Jpn.Soc.Neurochem. 43
  
  Pages: 505-505
- Data Source
  KAKENHI-PROJECT-16700327
[Journal Article] Syntaxin 5 interacts with Presenilin holoproteins, but not with their N- or C-terminal fragments, and affects the production of Aβ peptides2004
- Author(s)
  Kei Suga, Takami Tomiyama et al.
- Journal Title
  
  Biochem.J. 381, part3
  
  Pages: 619-628
- Data Source
  KAKENHI-PROJECT-16700327
[Presentation] 発現ベクターに挿入したカルシウムポンプSPCA1遺伝子に生じた異常スプライシング2023
- Author(s)
  山本幸子、須賀圭、丑丸真
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05151
[Presentation] Effect of chemical chaperone PBA on Golgi stress induced changes in Abeta peptide production and caspase3-dependent apoptosis in neuronal cells2020
- Author(s)
  Suga K, Yamamoto S., Terao Y., Akagawa K., Ushimaru M.
- Organizer
  第63回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-18K06468
[Presentation] 分泌経路型Ca2+/Mn2+ATPaseの特異的阻害剤の探索2019
- Author(s)
  山本　幸子、須賀　圭、誉田　晴夫、丑丸　真
- Organizer
  第92回日本生化学大会
- Data Source
  KAKENHI-PROJECT-18K06468
[Presentation] Golgi stress affects betaAPP processing and induces caspase3-dependent apoptosis in neuronal cells2019
- Author(s)
  Suga K, Yamamoto S., Nishino M., Terao Y., Akagawa K., Ushimaru M.
- Organizer
  第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-18K06468
[Presentation] ヘルペスウイルス感染細胞から神経細胞傷害活性をもつユビキチンやα-シヌクレイン凝集物が産生される2019
- Author(s)
  小久保友絵、中曽一裕、須賀圭、杉本温子、渡辺匡史、藤室雅弘
- Organizer
  第139回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-18K06468
[Presentation] Effect of Chemical chaperone on ER-Golgi SNARE expression and Abeta peptide production in neuronal cells2018
- Author(s)
  Suga K, Yamamoto S., Nishino M., Terao Y., Akagawa K., Ushimaru M
- Organizer
  第61回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-18K06468
[Presentation] Effect of ER and Golgi stress inducers on apoptotic cells assessed by Caspase3 activation using Time lapse imaging analyses2018
- Author(s)
  Nishino M., Suga K., Yamamoto S., Ushimaru M
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06468
[Presentation] Upregulation of ER-Golgi SNARE Syntaxin5 by ER stress and its relationship with βAPP processing2015
- Author(s)
  Kei Suga, Ayako Saito, Tatsuya Mishima, and Kimio Akagawa
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25430072
[Presentation] ER stress suppress Abeta secretion and induces the expression of ER-Golgi SNARE including Syntaxin5 proteins in neuronal cells2013
- Author(s)
  Suga K, Saito A, Mishima T, Akagawa K
- Organizer
  第56回日本神経化学会大会
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25430072
[Presentation] 神経細胞における小胞体ストレスはＡｂ分泌の抑制とsyntaxin5を含むER-Golgi SNAREの発現量の上昇を引き起こす2013
- Author(s)
  須賀圭、斎藤綾子、赤川公朗
- Organizer
  日本神経化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24300142
[Presentation] Up-regulation of Syntaxin5 protein expression under ER stress2010
- Author(s)
  須賀圭,齋藤綾子、三嶋竜弥、赤川公朗
- Organizer
  第53回日本神経化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] Syntaxin5の発現量は小胞体ストレスにより上昇する2010
- Author(s)
  須賀圭, 齋藤綾子, 三嶋竜弥, 赤川公朗
- Organizer
  第53回日本神経化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] 小胞体ストレスにおけるSNARE蛋白質の役割2009
- Author(s)
  須賀圭, 齋藤綾子, 三嶋竜弥, 赤川公朗
- Organizer
  第38回杏林医学会
- Place of Presentation
  東京
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] 小胞体とゴルジ体での・APPのプロセシングと細胞内輸送におけるSyntaxin5アイソフォムの役割2009
- Author(s)
  須賀圭, 齋藤綾子, 富山貴美, 森啓, 赤川公朗
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  伊香保
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] 小胞体とゴルジ体での・APPのプロセシングと細胞内輸送におけるSyntaxin5アイソフォームの役割2009
- Author(s)
  須賀圭,齋藤綾子,富山貴美,森啓,赤川公朗
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  伊香保
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] 小胞体とゴルジ体でのβAPPのプロセシングと細胞内輸送におけるSyntaxin5アイソフォームの役割2009
- Author(s)
  須賀圭, 齋藤綾子, 富山貴美, 森啓, 赤川公朗
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  伊香保
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] Role of Syntaxin5 isoforms on the processing and trafficking of bAPP in the ER through the Golgi compartments.2009
- Author(s)
  K.Suga, et al.
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  伊香保
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model Keystone Symposia2009
- Author(s)
  Iijima T, Tanaka K, Matsubara S, Kawakami H, Mishima T, Suga K, Akagawa K, Iwao Y
- Organizer
  Mitochondrial dynamics and Physiology
- Place of Presentation
  Whistler, Canada
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-19591818
[Presentation] Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model2009
- Author(s)
  Iijima T, Tanaka K, Matsubara S, Hayato K, Mishima T, Suga K, Akagawa K, Iwao K
- Organizer
  “Mitochondria Dynamics and Physiology" Keystone symposia
- Place of Presentation
  ウィスラーカナダ
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-19591818
[Presentation] Distinct effect of Syntaxin5 isofonus on the processing of βAPP2008
- Author(s)
  須賀圭, 齋藤綾子, 富山貴美, 森啓, 赤川公朗
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] アルツハイマー病関連蛋白質のプロセッシングと輸送におけるSyntaxin5の役割2007
- Author(s)
  須賀圭, 赤川公朗
- Organizer
  第36回杏林医学会
- Place of Presentation
  東京
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] Effect of syntaxin5 isoforms on the accumulation ofintracellular bAPP and the secretion of Ab peptides2007
- Author(s)
  K.Suga
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Ca^<++> buffering capacity of mitochondria after oxygen glucose deprivation in hippocampal neuron2007
- Author(s)
  Tanaka K, Iijima T, Mishima T, Suga K, Akagawa K
- Organizer
  Annual meeting of American Society of Anesthesiologists
- Place of Presentation
  San Francisco
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19591818
[Presentation] Effects of Syntaxin5 isoforms on the accumulation of intracellular βAPP and the secretion of Aβ peptides2007
- Author(s)
  須賀圭, 齋藤綾子, 富山貴美, 森啓, 赤川公朗
- Organizer
  第50回日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19500327
[Presentation] 小胞輸送系の制御におけるBAG6複合体の機能解明
- Author(s)
  土屋悠吾、須賀　圭、川原裕之
- Organizer
  第37回日本分子生物会大会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25430072
[Presentation] Upregulation of ER-Goligi SNARE syntaxin5 by ER stress and its relation with beta APP processing
- Author(s)
  K.Suga, A.Saito, T.Mishima & K.Akagawa
- Organizer
  日本神経化学会大会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300142
[Presentation] Upregulation of ER-Golgi SNARE Syntaxin5 by ER stress and its relationship with βAPP processing
- Author(s)
  Kei Suga, Ayako Saito, and Kimio Akagawa
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25430072

1. MISHIMA Tatsuya (40317095)

# of Collaborated Projects: 7 results

# of Collaborated Products: 22 results
2. SAITOU Ayako (80424109)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
3. KOFUJI Takefumi (40365200)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. AKAGAWA Kimio (80129303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. FUJIWARA Tomonori (90255399)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SANADA Masumi (70424108)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 山本幸子 (70434719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. IIJIMA Takehiko (10193129)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. NAKAYAMA Takahiro (90342823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 丑丸真 (40265765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 櫻井拓也 (20353477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Suga Kei 須賀 圭

須賀 圭 スガ ケイ

SUGA Kei 須賀 圭

Research Projects

Research Products

Co-Researchers

Analysis of molecular mechanisms of breast cancer malignant progression focusing on a regulator of Ca2+ pump SPCA2.

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Regulation of Abeta secretion and protective mechanisms by Golgi stress responsive factor Syx5 and chemical compound in neuronal cellsPrincipal Investigator

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Role for ER stress responsive ER-Golgi SNARE in processing of Alzheimer`s disease-related protein and autophagyPrincipal Investigator

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Functional difference between syntaxin1 isoforms in synaptic transmission

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Analysis of syntaxin 1 gene knockout mice as an animal model for autistic disorder

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Role of Syntaxin5 isoforms in neuronal cells under ER stressPrincipal Investigator

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Brain protection through calcium buffering system in mitochondria

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アルツハイマー病関連蛋白質の細胞内輸送におけるSyntaxinファミリーの役割Principal Investigator

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Project Period (FY)

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Research Institution

[Book] 生体の科学2004

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[Journal Article] Cytoplasmic control of Rab family small GTPases through BAG62019

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DOI

NAID

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[Journal Article] Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells2016

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DOI

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[Journal Article] ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid beta peptide secretion.2015

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[Journal Article] Data for the effects of ER and Golgi stresses on the ER-Golgi SNARE Syntaxin5 expression and on the βAPP processing in cultured hippocampal neurons2015

Author(s)

Journal Title

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Data Source

[Journal Article] ER and Golgi stresses increase ER-Golgi SNARE Syntaxin5: Implications for organelle stress and βAPP processing2015

Suga Kei 須賀圭

須賀圭スガケイ

SUGA Kei 須賀圭