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Hiroi Yukio
廣井 透雄
Connect your ORCID iD
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Alternative Names
HIROI Yukio 廣井 透雄
広井 透雄 ヒロイ ユキオ
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Researcher Number
30311624
Other IDs
Affiliation (Current)
2021: 国立研究開発法人国立国際医療研究センター, その他部局等, 科長
Affiliation (based on the past Project Information)
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2012: 東京大学, 医学部附属病院, 講師
2010 – 2011: 東京大学, 医学部附属病院, 特任講師
2002: Tokyo University, University Hospital, Assistant, 医学部付属病院, 助手
2002: The University of Tokyo Hospital, Research Associate, 医学部附属病院, Research Associate
1999 – 2001: 東京大学, 医学部・附属病院, 助手
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine
/
Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine
/
Biological Sciences
Keywords
Principal Investigator
Tbx5 / ANP / Csx / 分子心臓病学 / リン酸化 / DNA-PKcs / Ku70 / Ku80 / 転写因子 / 心筋
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More
/ 翻訳後修飾 / 協調作用 / 心奇形 / Holt-Oram症候群 / Nkx2-5 / synergistic action / cardiac defect / Holt-Oram syndrome
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More
Except Principal Investigator
転写因子 / BMP / Smad / ATF-2 / TAK1 / 動脈硬化 / 骨髄細胞 / 血管新生 / P19CL6 / P19CL6細胞 / 心筋梗塞 / 心肥大 / 組織リモデリング / 生活習慣病 / LIF / VEGF / GFP / 心筋細胞分化 / KLF5 / 平滑筋 / 分化 / SM1 / 2遺伝子 / ノックインマウス / 創傷 / 細胞融合 / 心筋分化 / 発生 / 分化転換 / CSX / Wnt / Midori / GATA4 / MEF2 / Cal / LIMタンパク / Csx / Nkx2.5 / DNA chip / MEF2C / PET / レポーター / 低酸素 / HIF-1 / トランスジェニックマウス / エンハンサー / 組織特異的遺伝子改変マウス / 増殖因子 / Creリコンビナーゼ / プラスミド / 心臓リモデリング / 骨格筋 / 共培養 / アポトーシス / 遺伝子治療 / 幹細胞 / 心筋細胞 / 骨格筋細胞 / ANP / GATA / 心不全 / TAK / myocardial infarction / plasmid / cardiac remodeling / skeletal muscle / coculture / 再生医療 / TAk1 / 協調作用 / Regeneration Medicine / Transcription Factor / Cardiomyocyte Differentiation / 創薬 / 遺伝子改変マウス / Klotho / Klf5 / 老化 / 線維化 / tissue remodeling / transcription factor / drug discovery / atherosclerosis / metabolic syndrome / gene engineered mouse / klotho
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Research Projects
(
9
results)
Research Products
(
2
results)
Co-Researchers
(
7
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Posttranscriptional modification of cardiac transcriptional factors and its role in cardiac development
Principal Investigator
Principal Investigator
HIROI Yukio
Project Period (FY)
2010 – 2012
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokyo
PETを用い生体で遺伝子発現をリアルタイムにイメージングする方法の開発
Principal Investigator
MAEMURA Koji
Project Period (FY)
2002
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokyo
心血管特異的薬剤誘導型遺伝子改変マウスの開発
Principal Investigator
永井 良三
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokyo
Molecular mechanism of organ remodeling : Gene transcription and cell-cell interaction in mesenchymal
Principal Investigator
NAGAI Ryozo
Project Period (FY)
2002 – 2006
Research Category
Grant-in-Aid for Scientific Research (S)
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokyo
細胞分化による心不全の遺伝子治療
Principal Investigator
KOMURO Issei
Project Period (FY)
2000 – 2004
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Chiba University
Isolation and analysis of molecules which associate with Csx
Principal Investigator
Principal Investigator
HIROI Yukio
Project Period (FY)
2000 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokyo
Gene therapy and cell transplantation for heart failure.
Principal Investigator
COMURO Issei
Project Period (FY)
2000 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Circulatory organs internal medicine
Research Institution
Chiba University
Analysis for Molecular Mechanism of Cardiomyocyte Differentiation by Using a Cell Line Which Efficiently Differentiates into Cardiomyocytes
Principal Investigator
HAYASHI Doubun
Project Period (FY)
2000 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Institution
The University of Tokyo
血管病変を形成する平滑筋細胞の起源の解明
Principal Investigator
NAGAI Ryozo
Project Period (FY)
1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokyo
All
2001
All
Journal Article
[Journal Article] Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.
2001
Author(s)
Hiroi Y., et. al.
Journal Title
Nat Genet 28(3)
Pages
: 276-280
Description
「研究成果報告書概要(和文)」より
Data Source
KAKENHI-PROJECT-12835003
[Journal Article] Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte defferentiation.
2001
Author(s)
Hiroi Y., et. al.
Journal Title
Nat Genet 28(3)
Pages
: 276-280
Description
「研究成果報告書概要(欧文)」より
Data Source
KAKENHI-PROJECT-12835003
# of Projects (Dsc)
# of Projects (Asc)
1.
KOMURO Issei
(30260483)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
2.
NAGAI Ryozo
(60207975)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
3.
MAEMURA Koji
(90282649)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
MANABE Ichiro
(70359628)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
HAYASHI Dobun
(80313104)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
永井 敏雄
(00334194)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
KOIBUCHI Nobutaka
(30456131)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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