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Hiroi Yukio  廣井 透雄

ORCIDConnect your ORCID iD *help
… Alternative Names

HIROI Yukio  廣井 透雄

広井 透雄  ヒロイ ユキオ

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Researcher Number 30311624
Other IDs
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立国際医療センター, 科長
Affiliation (based on the past Project Information) *help 2012: 東京大学, 医学部附属病院, 講師
2010 – 2011: 東京大学, 医学部附属病院, 特任講師
2002: Tokyo University, University Hospital, Assistant, 医学部付属病院, 助手
2002: The University of Tokyo Hospital, Research Associate, 医学部附属病院, Research Associate
1999 – 2001: 東京大学, 医学部・附属病院, 助手
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine / Biological Sciences
Keywords
Principal Investigator
ANP / Tbx5 / Csx / Holt-Oram syndrome / cardiac defect / synergistic action / Nkx2-5 / Holt-Oram症候群 / 心奇形 / 協調作用 … More / 翻訳後修飾 / 心筋 / 転写因子 / Ku80 / Ku70 / DNA-PKcs / リン酸化 / 分子心臓病学 … More
Except Principal Investigator
ATF-2 / Smad / BMP / 転写因子 / 動脈硬化 / TAK1 / KLF5 / 心筋細胞分化 / GFP / VEGF / LIF / 生活習慣病 / 組織リモデリング / 心肥大 / 心筋梗塞 / P19CL6細胞 / P19CL6 / 血管新生 / 骨髄細胞 / klotho / gene engineered mouse / metabolic syndrome / atherosclerosis / drug discovery / transcription factor / tissue remodeling / 線維化 / 老化 / Klf5 / Klotho / 遺伝子改変マウス / 創薬 / Cardiomyocyte Differentiation / Transcription Factor / Regeneration Medicine / 協調作用 / TAk1 / 再生医療 / coculture / skeletal muscle / cardiac remodeling / plasmid / myocardial infarction / TAK / 心不全 / GATA / ANP / 骨格筋細胞 / 心筋細胞 / 幹細胞 / 遺伝子治療 / アポトーシス / 共培養 / 骨格筋 / 心臓リモデリング / プラスミド / Creリコンビナーゼ / 増殖因子 / 組織特異的遺伝子改変マウス / エンハンサー / トランスジェニックマウス / HIF-1 / 低酸素 / レポーター / PET / MEF2C / DNA chip / Nkx2.5 / Csx / LIMタンパク / Cal / MEF2 / GATA4 / Midori / Wnt / CSX / 分化転換 / 発生 / 心筋分化 / 細胞融合 / 創傷 / ノックインマウス / 2遺伝子 / SM1 / 分化 / 平滑筋 Less
  • Research Projects

    (9 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (7 People)
  •  Posttranscriptional modification of cardiac transcriptional factors and its role in cardiac developmentPrincipal Investigator

    • Principal Investigator
      HIROI Yukio
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  PETを用い生体で遺伝子発現をリアルタイムにイメージングする方法の開発

    • Principal Investigator
      MAEMURA Koji
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  心血管特異的薬剤誘導型遺伝子改変マウスの開発

    • Principal Investigator
      永井 良三
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of organ remodeling : Gene transcription and cell-cell interaction in mesenchymal

    • Principal Investigator
      NAGAI Ryozo
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  細胞分化による心不全の遺伝子治療

    • Principal Investigator
      KOMURO Issei
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Chiba University
  •  Isolation and analysis of molecules which associate with CsxPrincipal Investigator

    • Principal Investigator
      HIROI Yukio
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Gene therapy and cell transplantation for heart failure.

    • Principal Investigator
      COMURO Issei
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Chiba University
  •  Analysis for Molecular Mechanism of Cardiomyocyte Differentiation by Using a Cell Line Which Efficiently Differentiates into Cardiomyocytes

    • Principal Investigator
      HAYASHI Doubun
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Institution
      The University of Tokyo
  •  血管病変を形成する平滑筋細胞の起源の解明

    • Principal Investigator
      NAGAI Ryozo
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo

All 2001

All Journal Article

  • [Journal Article] Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.2001

    • Author(s)
      Hiroi Y., et. al.
    • Journal Title

      Nat Genet 28(3)

      Pages: 276-280

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12835003
  • [Journal Article] Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte defferentiation.2001

    • Author(s)
      Hiroi Y., et. al.
    • Journal Title

      Nat Genet 28(3)

      Pages: 276-280

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12835003
  • 1.  KOMURO Issei (30260483)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  NAGAI Ryozo (60207975)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  MAEMURA Koji (90282649)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MANABE Ichiro (70359628)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  HAYASHI Dobun (80313104)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  永井 敏雄 (00334194)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KOIBUCHI Nobutaka (30456131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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