Hashimoto Wataru 橋元亘

… Alternative Names

HASHIMOTO Wataru 橋元亘

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Researcher Number	30323033
External Links
Affiliation (based on the past Project Information) *help	2012 – 2015: 東北大学, 大学病院, 助教 2007: Tohoku University, 病院, 助教 2005 – 2006: Tohoku University, Hospital, Assistant Professor, 病院, 助手 2004 – 2006: Tohoku University, Hospital, Assistant Professor, 病院・助手 2004: 東北大学, 大学病院, 助手 2001 – 2003: 東北大学, 歯学部附属病院, 助手 2000 – 2001: 東北大学, 歯学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Surgical dentistry / Surgical dentistry Except Principal Investigator Surgical dentistry / Surgical dentistry
Keywords	Principal Investigator IFN-γ / 抗腫瘍効果 / innate immunity / dendritic cells / galactosylceramide / 樹状細胞 / IL-12 / NKT細胞 / 糖脂質 / アポトーシス … More / 口腔癌 / head and neck tumor / apoptosis / natural killer T cells / antitumor effect / 頭頸部腫瘍 / 頭頚部腫瘍 / tumor immunotherapy / Intratumoral injection / NKT cells / antitumor effects / 癌免疫療法 / 腫瘍内投与 / 口腔癌、前癌病変の診断法 / ヒト型モデル / 口腔癌、前癌病変 / 免疫制御受容体 / 新規癌マーカー / siRNA法 / 口腔癌細胞株 / 放射線治療 / 抗癌剤感受性 / 癌分子治療 … More Except Principal Investigator specific immunity / innate immunity / IFN-γ / IL-18 / アポトーシス / 樹状細胞 / IL-12 / NK細胞 / 抗腫瘍効果 / Reactive oxygen species / Cytochrome C / Mitochondria / Caspase / Apoptosis / Cisplatin / Selenium compounds / Taxotere / 膜電位 / 増強剤 / グルタチオン / epigenetics / 併用療法 / 活性酸素 / チトクロームC / ミトコンドリア / カスパーゼ / シスプラチン / セレニウム化合物 / タキソテール / dendriticcells / apoptosis / natural killer cells / antitumor / dendritic cells / NK cells / antitumor effect / CTL Less

Development of effective diagnostic methods and treatment of oral cancer and pre-cancerous lesionsPrincipal Investigator
- Principal Investigator
  
  Hashimoto Wataru
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University
口腔癌に対する化学療法のSurvivin発現への影響と発現調節による口腔癌治療Principal Investigator
- Principal Investigator
  
  橋元亘
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University
Mechanisms of Taxotere-induced apoptosis in or a squamous cell carcinoma.
- Principal Investigator
  
  RIKIISHI Hidemi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  TOHOKU UNIVERSITY
Basic research of cancer immunotherapy by using dendritic cells and clinical applications for head and neck tumors ; by using galactosylceramidePrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Wataru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  TOHOKU UNIVERSITY
Interleukin-18 activates Natural Killer cells and induces tumor apoptosis ; clinical applications for head and neck tumors.
- Principal Investigator
  
  ECHIGO Seishi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University
An analysis for mechanism of antitumor effects of dendritic cells treated with αGalactosylceramidePrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Wataru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  TOHOKU UNIVERSITY
An analysis for mechanism of antitumor effects of IL-18 and a clinical application of IL-18 for head and neck tumors
- Principal Investigator
  
  ECHIGO Seishi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  TOHOKU UNIVERSITY

All 2015 2014 2013 2012 2003 2002 Other

All Journal Article Presentation

[Journal Article] 口腔粘膜悪性黒色腫の治療法別生存率の解析2013
- Author(s)
  菅崎　将樹、橋元　亘、熊本裕行、高橋　哲
- Journal Title
  
  東北大学歯学雑誌
  
  Volume: 32 Pages: 50-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593023
[Journal Article] 舌部分切除後の創面に対してポリグリコール酸シート（ネオベール）およびフィブリン糊(ボルヒール）を併用した被覆法の使用経験-特に術後出血について-2012
- Author(s)
  谷口貴洋、逸見健明、橋元亘、大泉丈史、栗原淳、篠原文明、廣谷拓章、森川秀広、森士朗、高橋哲
- Journal Title
  
  東北大学歯学雑誌
  
  Volume: 31 Pages: 87-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593023
[Journal Article] Interleukin-18によるNatural Killer (NK)細胞活性化および腫瘍細胞のアポトーシス誘導2003
- Author(s)
  橋元亘 3名
- Journal Title
  
  頭頸部腫瘍 29
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] NK but mot NKT cells play a necessary role to promote an innate antitumor2003
- Author(s)
  W.Hashimoto 他6名
- Journal Title
  
  Int.J.Cancer 103
  
  Pages: 508-513
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] Interleukin-18 (IL-18) activates natural killer cells and induces tumor apoptosis.2003
- Author(s)
  W.Hashimoto et al.
- Journal Title
  
  Head and Neck Cancer 29
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] Interleukin-18によるNatural killer(NK)細胞活性化および腫瘍細胞のアポトーシス誘導2003
- Author(s)
  橋元亘他3名
- Journal Title
  
  頭頸部腫瘍 29
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] NK but not NKT cells play a necessary role to promote an innate antitumor response induced by IL-18.2003
- Author(s)
  W.Hashimoto et al.
- Journal Title
  
  Int.J.Cancer 103
  
  Pages: 508-513
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] NK but not NKT cells play a necessary role to promote an innate antitumor response induced by IL-18.2003
- Author(s)
  W.Hashimoto他6名
- Journal Title
  
  Int.J.Cancer 103
  
  Pages: 508-513
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] Therapeutic and specific antitumor immunity induced by co-administration if immature dendritic cells and adenoviral vector expression biologically active IL-18.2002
- Author(s)
  F.Tanaka, W.Hashimoto et al.
- Journal Title
  
  Gene Therapy 21
  
  Pages: 1480-1486
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] Interleukin-12 administration is more Effective for preventing metastases than for inhibiting primary Established tumors in a murine model of spontaneous hepatic metastases.2002
- Author(s)
  T.Kobayashi, W.Hashimoto et al.
- Journal Title
  
  Surg.Today 32
  
  Pages: 236-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] Therapeutic and specific antitumor immunity induced by co-administration of dendritic cells2002
- Author(s)
  F.Yanaka, W.Hashimoto他3名
- Journal Title
  
  Gene Therapy 21
  
  Pages: 1480-1486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] Uridine Phosphorelase is a potential prognostic factor in oral squamous cell carcinoma.2002
- Author(s)
  H.Miyashita, W.Hashimoto et al.
- Journal Title
  
  Cacer 94
  
  Pages: 2959-2966
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Journal Article] Interleukin-12 administration is more effective for preventing metastases than for inhibiting primary2002
- Author(s)
  T.Kobayashi, W.Hashimoto他5名
- Journal Title
  
  Surg.Today 32
  
  Pages: 236-242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370655
[Presentation] 当科における口腔表在癌の臨床的検討2015
- Author(s)
  橋元亘、阿部慧子、森士朗、栗原淳、野上晋之介、宮下仁、山内健介、熊本裕行、高橋哲
- Organizer
  第69回日本口腔科学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-24593023
[Presentation] 粘膜角化性病口腔変を認めた口腔癌に関する臨床的検討2014
- Author(s)
  栗原　淳，纐纈　衆，山口佳宏，蔡　優広，橋元　亘，森　士朗，髙橋　哲
- Organizer
  第32回口腔腫瘍学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24593023
[Presentation] 当科における口腔表在癌の臨床的検討2014
- Author(s)
  橋元亘，森　士朗，栗原　淳, 野上晋之介，宮下　仁, 山内健介, 高橋哲
- Organizer
  第38回頭頸部癌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24593023
[Presentation] 当科における口腔表在癌の臨床的検討
- Author(s)
  橋元　亘、森　士朗、栗原　淳、野上晋之介、宮下　仁、山内健介、高橋　哲
- Organizer
  第38回日本頭頸部癌学会総会
- Place of Presentation
  東京ファッションビルホール（東京）
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24593023

1. ECHIGO Seishi (70005114)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. MORIKAWA Hidehiro (60302155)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. OGASAWARA KOUETSU (30323603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TANIGUCHI TAKAHIRO (40444012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. RIKIISHI Hidemi (70091767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hashimoto Wataru 橋元 亘

HASHIMOTO Wataru 橋元 亘

Research Projects

Research Products

Co-Researchers

Development of effective diagnostic methods and treatment of oral cancer and pre-cancerous lesionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

口腔癌に対する化学療法のSurvivin発現への影響と発現調節による口腔癌治療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of Taxotere-induced apoptosis in or a squamous cell carcinoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research of cancer immunotherapy by using dendritic cells and clinical applications for head and neck tumors ; by using galactosylceramidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interleukin-18 activates Natural Killer cells and induces tumor apoptosis ; clinical applications for head and neck tumors.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An analysis for mechanism of antitumor effects of dendritic cells treated with αGalactosylceramidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An analysis for mechanism of antitumor effects of IL-18 and a clinical application of IL-18 for head and neck tumors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 口腔粘膜悪性黒色腫の治療法別生存率の解析2013

Author(s)

Journal Title

Data Source

[Journal Article] 舌部分切除後の創面に対してポリグリコール酸シート（ネオベール）およびフィブリン糊(ボルヒール）を併用した被覆法の使用経験-特に術後出血について-2012

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-18によるNatural Killer (NK)細胞活性化および腫瘍細胞のアポトーシス誘導2003

Author(s)

Journal Title

Data Source

[Journal Article] NK but mot NKT cells play a necessary role to promote an innate antitumor2003

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-18 (IL-18) activates natural killer cells and induces tumor apoptosis.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Interleukin-18によるNatural killer(NK)細胞活性化および腫瘍細胞のアポトーシス誘導2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] NK but not NKT cells play a necessary role to promote an innate antitumor response induced by IL-18.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] NK but not NKT cells play a necessary role to promote an innate antitumor response induced by IL-18.2003

Author(s)

Hashimoto Wataru 橋元亘

HASHIMOTO Wataru 橋元亘