KANZAKI Hiroyuki 菅崎弘幸

Researcher Number	30333826
Other IDs	https://orcid.org/0000-0003-3473-1218
External Links
Affiliation (Current)	2025: 鶴見大学, 歯学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 鶴見大学, 歯学部, 准教授 2014 – 2015: 鶴見大学, 歯学部, 講師 2012 – 2013: 東北大学, 大学病院, 助教 2011: 東北大学, 病院, 助教 2007: Tohoku University Hospital, 病院, Assistant Professor 2005 – 2006: 東北大学, 病院, 助手 2004 – 2006: 東北大学, 病院・助手
Review Section/Research Field	Principal Investigator Basic Section 57070:Developmental dentistry-related / Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry / Surgical dentistry Except Principal Investigator Basic Section 57070:Developmental dentistry-related / Orthodontics/Pediatric dentistry / Orthodontic/Pediatric dentistry
Keywords	Principal Investigator Nrf2 / Reactive oxygen species / oxidative stress / メカニカルストレス / サイトカイン / TACE / 破骨細胞 / osteoclast / myo-inositol / 石灰化 … More / 骨芽細胞分化 / ピロリン酸 / 異所性石灰化 / ENPP1 / エピジェネティック / 顎関節 / 転写 / nrf2 / エピジェネティクス / 抗酸化 / 骨代謝 / 酸化ストレス / 抗酸化酵素 / 軟骨 / エピゲノム / ADAM / 腫瘍細胞 / インターフェロンガンマ / NK細胞 / ADAM17 / インターフェロンγ / ADAM１７ / 腫瘍免疫 / インターフェロン / 歯周組織 / 免疫系細胞 / Regulatory T cell / Keap1/Nrf2 / foxp3 / Keap1 / Treg / 破歯細胞 / 歯根吸収 / IGF-1 / 顎変形症 / 顎顔面頭蓋 / 開咬 / 非ウイルス / 咀嚼筋 / 局所的遺伝子導入法 … More Except Principal Investigator 歯根膜 / 骨芽細胞 / 歯周組織 / 歯肉 / メカニカルストレス / Nrf2 / 線維芽細胞 / 歯周病 / エピゲノム / 抗酸化酵素 / リン酸 / 歯根膜線維芽細胞 / 骨形成 / 骨吸収 / 破骨細胞 / 歯根膜細胞 / 咀嚼 / 不正咬合 / 顎変形症 / 認知機能 / アイトラッキング / 顎運動 / NIRS / 脳血流 / 異所性石灰化 / ピロリン酸 / 高リン酸血症モデルラット / 歯髄 / 炎症反応 / 抗酸化酵素Nrf2活性化剤 / 細胞膜透過性ペプチド / 瘢痕形成 / 唇顎口蓋裂 / 酸化ストレス / 上皮間葉移行 / tgf beta / EMT / 瘢痕 / 分化 / 運命 / 運命決定 / 細胞分化 / 遺伝子発現 / メチル化 / ヒストン / エピゲノム制御 / 細胞運命 / 骨代謝 / 分泌 / エクソソーム / miRNA / ビスフォスフォネート製剤 / マクロファージ / 顎骨壊死 / ビスフォスフォネート / 心身機能 / 口腔機能 / 小児閉塞性睡眠時無呼吸 / OSA / 脳波 / ウェアラブルデバイス / 睡眠 / 睡眠呼吸障害 / 顎整形力 / 歯科矯正用アンカースクリュー / oral appliance / 持続的陽圧呼吸療法 / うつ病 / 外科的矯正治療 / 閉塞性睡眠時無呼吸 / フォスフォノギ酸 / 高リン血症モデルラット / 高リン血症 / ナトリウム依存性リン酸トランスポター / アルカリフォスファターゼ / ナトリウム依存性リン酸トランスポーター / サイトカイン / 歯の移動 / シグナル伝達 / 歯槽骨 / 矯正学的歯の移動 / マイクロRNA / H3k9me3 / H3k9me2 / H3k9me1 / H3K9 metyltransferases / H3K9 / Glp / G9a / エピジェネティクス / Osteoclasts / Osteoblasts / Periodontal ligament cells / Remodeling / Orthodontic tooth movement / Gene transfer / Periodontal tissue / Mechanical stress / BMP-4 / RANKL / OPG / アポトーシス / 血管新生因子 / 超音波 / Bone Morphogenetic Protein / エレクトロポレーション / リモデリング / 骨改造 / 歯科矯正学的歯の移動 / 遺伝子導入 Less

Does myo-inositol inhibit osteoclastogenesis via augmentation of Nrf2-mediated anti-oxidationPrincipal Investigator
- Principal Investigator
  
  菅崎弘幸
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
抗酸化酵素を利用した歯周組織破壊の防止
- Principal Investigator
  
  井田知美
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
歯髄・歯根膜細胞間の異所性石灰化耐性相違における細胞内リン酸流入機構の関与
- Principal Investigator
  
  石川美佐緒
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Elucidation of the inhibitory mechanism for chewing-induced brain blood flow in patients with jaw deformity.
- Principal Investigator
  
  熊澤正雄
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Exploration for exosome-borne signal transduction during alveolar bone remodeling under orthodontic force application
- Principal Investigator
  
  新井千博
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Exploration for epigenomic regulation of the cell fate among gingival and periodontal ligament fibroblasts
- Principal Investigator
  
  中村芳樹
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Inhibition of scar formation by Nrf2 activating via cell-penetrating peptide
- Principal Investigator
  
  勝又裕太
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Inhibition of abnormal calcification by augmented ENPP1 via Nrf2Principal Investigator
- Principal Investigator
  
  菅崎弘幸
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Regulation of bisphosphonate-related osteonecrosis by M2 macrophage differentiation via Nrf2 activation
- Principal Investigator
  
  和田悟史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kanazawa Medical University
  Tsurumi University
OSAの治療法の違いが抑うつ状態および高次脳機能に与える影響の検証
- Principal Investigator
  
  及川崇
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Elucidating the Impact of Novel Jaw Bone Growth Promotion Therapy on Pediatric Obstructive Sleep Apnea and Psychosomatic Functions
- Principal Investigator
  
  Tomonari Hiroshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Basic Study on the Differentiation Mechanism of Periodontal Ligament Fibroblasts by Phosphoric Acid dependent on ALP Activity
- Principal Investigator
  
  Ishikawa Misao
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Epigenetic control of the anti-oxidative stress tolerance in the specificity of the condylar cartilagePrincipal Investigator
- Principal Investigator
  
  Kanzaki Hiroyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tsurumi University
Elucidation of the epigenetically regulation of the phenotype of the periodontal ligament fibroblast
- Principal Investigator
  
  Yoshiki Nakamura
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tsurumi University
Elucidation of the microRNA-mediated control of the alveolar bone metabolism by PDL cells under each mechanical stresses
- Principal Investigator
  
  Noda Koji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tsurumi University
Elucidation of pro-metastatic property of interferon degradationPrincipal Investigator
- Principal Investigator
  
  KANZAKI Hiroyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Tsurumi University
  Tohoku University
Exprolation of regulatory mechanisms of root resorption by immune cellsPrincipal Investigator
- Principal Investigator
  
  KANZAKI Hiroyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Tohoku University
咀嚼筋への局所的遺伝子導入法を用いた筋機能改善とそれに伴う骨格性開咬の阻止Principal Investigator
- Principal Investigator
  
  菅崎弘幸
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Tohoku University
Analysis of periodontal tissue remodeling mechanism induced by mechanical stress and the regulation by gene transfer
- Principal Investigator
  
  CHIBA Mirei
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Tohoku University

[Journal Article] Mandibular Endochondral Growth Is Specifically Augmented by Nutritional Supplementation with Myo-Inositol Even in Rabbits2024
- Author(s)
  Shimoyama Miho、Kanzaki Hiroyuki、Tohyama Syunnosuke、Ida Tomomi、Ishikawa Misao、Katsumata Yuta、Arai Chihiro、Wada Satoshi、Manase Shugo、Tomonari Hiroshi
- Journal Title
  
  Dentistry Journal
  
  Volume: 12 Issue: 3 Pages: 49-49
- DOI
  10.3390/dj12030049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10197, KAKENHI-PROJECT-22K10256, KAKENHI-PROJECT-22K10257, KAKENHI-PROJECT-22K10281, KAKENHI-PROJECT-23K09427
[Journal Article] Myo-inositol augments chondrocytic differentiation2023
- Author(s)
  Tohyama S, Kanzaki H, Ishikawa M, Katsumata Y, Arai C, Ida T, Wada S, Shimoyama M, Manase S, Tomonari H
- Journal Title
  
  Dent Oral Craniofac Res
  
  Volume: 9 Issue: 1 Pages: 1-4
- DOI
  10.15761/domr.1000399
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K09448, KAKENHI-PROJECT-21K21026
[Journal Article] Early diagnosis of aortic calcification through dental X-ray examination for dental pulp stones2023
- Author(s)
  Ishikawa Misao、Kanzaki Hiroyuki、Kodera Ryo、Sekimizu Takehiro、Wada Satoshi、Tohyama Syunnosuke、Ida Tomomi、Shimoyama Miho、Manase Shugo、Tomonari Hiroshi、Kuroda Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 18576-18576
- DOI
  10.1038/s41598-023-45902-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10197, KAKENHI-PROJECT-21K10199, KAKENHI-PROJECT-22K10256, KAKENHI-PROJECT-22K10257, KAKENHI-PROJECT-22K10281, KAKENHI-PROJECT-23K09427, KAKENHI-PROJECT-23K09448
[Journal Article] Association between severity of malocclusion and parameters of oral functions in permanent dentition with various malocclusion: case-control study2023
- Author(s)
  Sasaki Yoji, Yamamoto Jun-Ichi, Kanzaki Hiroyuki, Shimpo Yudai, Miyamoto Yutaka, Kobayashi Fumitaka, Nishida Tomoko, Mizokami Kiichiro, Katayama Mao, Sekiya Toshiko, Nomura Yoshiaki, Tomonari Hiroshi
- Journal Title
  
  Clinical and Investigative Orthodontics
  
  Volume: 82 Issue: 4 Pages: 212-221
- DOI
  10.1080/27705781.2023.2267847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10238
[Journal Article] Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis2023
- Author(s)
  Ishii Takenobu、Ruiz‐Torruella Montserrat、Kim Jae Young、Kanzaki Hiroyuki、Albassam Abdullah、Wisitrasameewong Wichaya、Shindo Satoru、Pierrelus Roodelyne、Heidari Alireza、Kandalam Umadevi、Nakamura Shin、Movila Alexandru、Minond Dmitriy、Kawai Toshihisa
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 27 Issue: 12 Pages: 1750-1756
- DOI
  10.1111/jcmm.17416
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10197, KAKENHI-PROJECT-22K10281
[Journal Article] Intraperitoneal injection of Nrf2 activator inhibited calvarial bone destruction in mice2021
- Author(s)
  Ken Tanaka, Hiroyuki Kanzaki, Satoshi Wada, Yuta Katsumata, Tsuyoshi Narimiya, Hiroshi Tomonari
- Journal Title
  
  Dental, Oral and Maxillofacial Research
  
  Volume: 7 Issue: 1 Pages: 1-6
- DOI
  10.15761/domr.1000375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10199
[Journal Article] Chewing-induced Increase of Brain Blood Flow in Mandibular Prognathism Was Less Compared to Normal Occlusion2021
- Author(s)
  中村浩昭, 菅崎弘幸, 山田祐子, 村上真澄, 小澤絵里香, 狩谷千尋, 佐原早彩, 和田悟史, 及川崇, 友成博
- Journal Title
  
  The Japanese Journal of Jaw Deformities
  
  Volume: 31 Issue: 3 Pages: 172-180
- DOI
  10.5927/jjjd.31.172
- NAID
  130008079098
- ISSN
  0916-7048, 1884-5045
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10218
[Journal Article] 鶴見大学歯学部附属病院における先天性疾患に起因した不正咬合を伴う患者に関する実態調査2021
- Author(s)
  吉澤舞、菅崎弘幸、及川崇、関谷利子、勝又裕太、小澤絵理香、友成博
- Journal Title
  
  Orthodontic Waves-Japanese Edition
  
  Volume: 80 Pages: 12-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10218
[Journal Article] 鶴見大学歯学部附属病院矯正科における矯正単独治療と外科的矯正治療の PAR index を用いた治療成績の比較2021
- Author(s)
  小澤絵里香, 菅崎弘幸, 及川崇, 関谷利子, 勝又裕太, 吉沢舞, 狩谷千尋, 友成博
- Journal Title
  
  鶴見歯学
  
  Volume: 47 Pages: 67-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10218
[Journal Article] Nutritional supplementation with myo-inositol in growing mice specifically augments mandibular endochondral growth2019
- Author(s)
  Yamaguchi, Yuki Kanzaki, Hiroyuki Miyamoto, Yutaka Itohiya, Kanako Fukaya, Sari Katsumata, Yuuta Nakamura, Yoshiki
- Journal Title
  
  Bone
  
  Volume: 121 Pages: 181-190
- DOI
  10.1016/j.bone.2019.01.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05552
[Journal Article] Compression and tension variably alter Osteoprotegerin expression via miR-3198 in periodontal ligament cells2019
- Author(s)
  Kanzaki, Hiroyuki Wada, Satoshi Yamaguchi, Yuuki Katsumata, Yuta Itohiya, Kanako Fukaya, Sari Miyamoto, Yutaka Narimiya, Tsuyoshi Noda, Koji Nakamura, Yoshiki
- Journal Title
  
  BMC Molecular and Cell Biology
  
  Volume: 20 Issue: 1 Pages: 6-6
- DOI
  10.1186/s12860-019-0187-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05552
[Journal Article] Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression.2019
- Author(s)
  Tsuyoshi Narimiya, Hiroyuki Kanzaki, Yuki Yamaguchi, Satoshi Wada, Yuta Katsumata, Ken Tanaka, Hiroshi Tomonari
- Journal Title
  
  Bone Reports
  
  Volume: 11 Pages: 100228-100228
- DOI
  10.1016/j.bonr.2019.100228
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19304, KAKENHI-PROJECT-16H05552
[Journal Article] Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signaling by augmented anti oxidation2018
- Author(s)
  Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, Narimiya T, Wada S, Nakamura Y
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 22 Issue: 2 Pages: 1138-1147
- DOI
  10.1111/jcmm.13367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11797, KAKENHI-PROJECT-16H05552, KAKENHI-PROJECT-15K11356, KAKENHI-PROJECT-15K11376
[Journal Article] Single Local Injection of Epigallocatechin Gallate-Modified Gelatin Attenuates Bone Resorption and Orthodontic Tooth Movement in Mice2018
- Author(s)
  Katsumata, Yuta Kanzaki, Hiroyuki Honda, Yoshitomo Tanaka, Tomonari Yamaguchi, Yuuki Itohiya, Kanako Fukaya, Sari Miyamoto, Yutaka Narimiya, Tsuyoshi Wada, Satoshi Nakamura, Yoshiki
- Journal Title
  
  Polymers
  
  Volume: 10 Issue: 12 Pages: 1384-1384
- DOI
  10.3390/polym10121384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05552, KAKENHI-PROJECT-16K11797
[Journal Article] Orthodontic tooth movement and HMGB12018
- Author(s)
  Hiroyuki Kanzaki, Yoshiki Nakamura
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 60 Issue: 2 Pages: 49-53
- DOI
  10.1016/j.job.2018.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05552
[Journal Article] Novel device for application of continuous mechanical tensile strain to mammalian cells2017
- Author(s)
  Wada, Satoshi Kanzaki, Hiroyuki Narimiya, Tsuyoshi Nakamura, Yoshiki
- Journal Title
  
  Biology Open
  
  Volume: 6 Pages: 518-524
- DOI
  10.1242/bio.023671
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11376, KAKENHI-PROJECT-16K11797, KAKENHI-PROJECT-15K11356
[Journal Article] Orthodontic tensile strain induces angiogenesis via type IV collagen degradation by matrix metalloproteinase-122017
- Author(s)
  Narimiya, T. Wada, S. Kanzaki, H. Ishikawa, M. Tsuge, A. Yamaguchi, Y. Nakamura, Y.
- Journal Title
  
  J Periodontal Res
  
  Volume: 印刷中 Issue: 5 Pages: 1-11
- DOI
  10.1111/jre.12453
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11376, KAKENHI-PROJECT-16K11797, KAKENHI-PROJECT-16H05552, KAKENHI-PROJECT-15K11356
[Journal Article] Possible alternative treatment for mandibular asymmetry by local unilateral igf-1 injection into the mandibular condylar cavity: Experimental study in mice.2017
- Author(s)
  Fukaya S, Kanzaki H, Miyamoto Y, Yamaguchi Y, Nakamura Y.
- Journal Title
  
  American journal of orthodontics and dentofacial orthopedics
  
  Volume: 152(6) Issue: 6 Pages: 820-829
- DOI
  10.1016/j.ajodo.2017.05.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05552, KAKENHI-PROJECT-15K11356, KAKENHI-PROJECT-15K11376
[Journal Article] RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.2017
- Author(s)
  Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y
- Journal Title
  
  FASEB J
  
  Volume: 31 Issue: 2 Pages: 781-792
- DOI
  10.1096/fj.201600826r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11797, KAKENHI-PROJECT-16H05552, KAKENHI-PROJECT-15K11356, KAKENHI-PROJECT-15K11376
[Journal Article] Asporin stably expressed in the surface layer of mandibular condylar cartilage and augmented in the deeper layer with age2017
- Author(s)
  Miyamoto Y, Kanzaki H, Wada S, Tsuruoka S, Itohiya K, Kumagai K, Hamada Y, Nakamura Y
- Journal Title
  
  Bone Reports
  
  Volume: 7 Pages: 41-50
- DOI
  10.1016/j.bonr.2017.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11797, KAKENHI-PROJECT-15K11356, KAKENHI-PROJECT-15K11376
[Journal Article] Asporin stably expressed in the surface layer of mandibular condylar cartilage and augmented in the deeper layer with age.2017
- Author(s)
  Miyamoto Y, Kanzaki H, Wada S, Tsuruoka S, Itohiya K, Kumagai K, Hamada Y, Nakamura Y.
- Journal Title
  
  Bone reports
  
  Volume: 7 Pages: 41-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05552
[Journal Article] Novel device for application of continuous mechanical tensile strain to mammalian cells.2017
- Author(s)
  Wada S, Kanzaki H, Narimiya T, Nakamura Y.
- Journal Title
  
  Biology Open.
  
  Volume: 6(4) Pages: 518-524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05552
[Journal Article] The main occluding area in normal occlusion and mandibular prognathism2016
- Author(s)
  Kurokawa M., Kanzaki H., Tokiwa H., Handa H., Nakaoka K., Hamada Y., Kato H., Nakamura Y
- Journal Title
  
  Angle Orthod
  
  Volume: 86(1) Issue: 1 Pages: 87-93
- DOI
  10.2319/111114-807.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11356
[Journal Article] Occlusal hypofunction mediates alveolar bone apposition via relative augmentation of TGF-β signaling by decreased Asporin production in rats.2016
- Author(s)
  Kanako Itohiya Hiroyuki Kanzaki Misao Ishikawa Satoshi Wada Yutaka Miyamoto Tsuyoshi Narimiya Yoshiki Nakamura
- Journal Title
  
  Dental, Oral and Craniofacial Research
  
  Volume: 3 Issue: 1 Pages: 1-8
- DOI
  10.15761/docr.1000192
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11376
[Journal Article] Evaluation of antibacterial activity of visible light-responsive TiO2-based photocatalyst coating on orthodontic materials against cariogenic bacteria2016
- Author(s)
  Sudo T., Imai S., Ochiai T., Kanzaki H., Morita Y., Hanada N., Nakamura Y.
- Journal Title
  
  Asian Pac J Dent
  
  Volume: 16 Pages: 15-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11356
[Journal Article] Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes2016
- Author(s)
  Kanzaki, H. Shinohara, F. Kanako, I. Yamaguchi, Y. Fukaya, S. Miyamoto, Y. Wada, S. Nakamura, Y.
- Journal Title
  
  Redox Biol
  
  Volume: 8 Pages: 186-191
- DOI
  10.1016/j.redox.2016.01.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11376, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K11356, KAKENHI-PROJECT-16K11797
[Journal Article] A-Disintegrin and Metalloproteinase(ADAM) 17 Enzymatically Degrades Interferon-gamma2016
- Author(s)
  Kanzaki H., Shinohara F., Suzuki M., Wada S., Miyamoto Y., Yamaguchi Y., Katsumata Y., Makihira S., Kawai T., Taubman MA, Nakamura Y.
- Journal Title
  
  Sci Rep
  
  Volume: 30 Issue: 1
- DOI
  10.1038/srep32259
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11356, KAKENHI-PROJECT-16K11797
[Journal Article] Nrf2 activation attenuates both orthodontic tooth movement and relapse.2015
- Author(s)
  Kanzaki H, Shinohara F, Itohiya-Kasuya K, Ishikawa M, Nakamura Y.
- Journal Title
  
  J Dent Res
  
  Volume: 94 Issue: 6 Pages: 787-794
- DOI
  10.1177/0022034515577814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11356
[Journal Article] Nrf2 Activation Attenuates Both Orthodontic Tooth2015
- Author(s)
  Kanzaki, H., Shinohara, F., Kajiya, M., Fukaya, S., Miyamoto, Y., & Nakamura, Y.
- Journal Title
  
  Journal of Dental Research.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670841
[Journal Article] 細胞膜透遃性ペプチド7R-ETGEによる骨破壊性疾患の阻止2014
- Author(s)
  菅崎弘幸、篠原文明、加治屋幹人、小玉哲也
- Journal Title
  
  第26回バイオエンジニアリング講演会プロシーディング
  
  Volume: 13-69 Pages: 253-254
- Data Source
  KAKENHI-PROJECT-23689081
[Journal Article] Nuclear nrf2 induction by protein transduction attenuates osteoclastogenesis2014
- Author(s)
  Kanzaki, H. Shinohara, F. Kajiya, M. Fukaya, S. Miyamoto, Y. Nakamura, Y.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 77 Pages: 239-248
- DOI
  10.1016/j.freeradbiomed.2014.09.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670841
[Journal Article] 細胞膜透過性ペプチド7R-ETGEによる骨破壊性疾患の阻止2014
- Author(s)
  菅崎弘幸、篠原文明、加治屋幹人、小玉哲也
- Journal Title
  
  第26回バイオエンジニアリング講演会プロシーディング
  
  Volume: 13-69 Pages: 253-254
- Data Source
  KAKENHI-PROJECT-23689081
[Journal Article] The Keap1/Nrf2 axis plays a role in osteoclast differentiation by regulating intracellular ROS signaling.2013
- Author(s)
  H Kanzaki, F Shinohara, M Kajiya, T kodama
- Journal Title
  
  J Bio Chem
  
  Volume: 32 Issue: 32 Pages: 23009-23020
- DOI
  10.1074/jbc.m113.478545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592954, KAKENHI-PROJECT-23689081
[Journal Article] HVJ-E/importin- β hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery.2012
- Author(s)
  T Kawazu, H Kanzaki, A Uno, H Azuma, and T Nagasaki.
- Journal Title
  
  Biomed Pharmacother
  
  Volume: 66(7) Pages: 519-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689081
[Journal Article] Effects of local osteoprotegerin gene transfection on orthodontic root resorption during retention : an in vivo Micro-CT analysis.2012
- Author(s)
  N Zhao, Y Liu, H Kanzaki, W Liang, J Ni, J Lin.
- Journal Title
  
  Orthod Craniofac Res
  
  Volume: 15 Pages: 10-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689081
[Journal Article] HVJ-E/importin-β hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery2012
- Author(s)
  T.Kawazu, H.Kanzaki, A.Uno, H.Azuma, T.Nagasaki
- Journal Title
  
  Biomed. Biopharmacother.
  
  Volume: (印刷中) Issue: 7 Pages: 619-624
- DOI
  10.1016/j.biopha.2012.02.005
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23107527, KAKENHI-PROJECT-23500544, KAKENHI-PROJECT-23689081
[Journal Article] Inhibiti on of T-Cell-Mediated and Infection-Ind uced Periodontal Bone Resorption by TAC E Blockade2012
- Author(s)
  Kanzaki, H.; Han, X.; Asami, Y.; Suzu ki, M.; Kawai, T.; Taubman, M
- Journal Title
  
  In : Sasaki, K.; Suzuki, O.; Takahashi, N., eds. Interface Oral Hea lth Science 2011: Springer Japan
  
  Pages: 173-175
- DOI
  10.1007/978-4-431-54070-0_45
- ISBN
  9784431540694, 9784431540700
- Data Source
  KAKENHI-PROJECT-23689081
[Journal Article] Local osteoprotegerin gene transfer inhibits relapse of orthodontic tooth movement2012
- Author(s)
  Zhao, N.; Lin, J.; Kanzaki, H.; Ni, J.; Chen, Z.; Liang, W.; Liu, Y
- Journal Title
  
  American journal of orthodontics and de ntofacial orthopedics
  
  Volume: 141 Issue: 1 Pages: 30-40
- DOI
  10.1016/j.ajodo.2011.06.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689081
[Journal Article] Effects of local o steoprotegerin gene transfection on ort hodontic root resorption during retenti on : an in vivo micro-CT analysis2012
- Author(s)
  Zhao, N.; Liu, Y.; Kanzaki, H.; Liang, W.; Ni, J.; Lin, J
- Journal Title
  
  Ortho dontics & craniofacial research
  
  Volume: 15 Issue: 1 Pages: 10-20
- DOI
  10.1111/j.1601-6343.2011.01532.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689081
[Journal Article] Local osteoprotegerin gene transfer to periodontal tissue inhibits lipopolysaccharide-induced alveolar bone resorption.2008
- Author(s)
  Chen R, Kanzaki H, Chiba M, Nishimura M, Kanzaki R, Igarashi K.
- Journal Title
  
  J Periodontal Res. 43
  
  Pages: 237-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local osteoprotegerin gene transfer to periodontal tissue inhibits lipopolysaccharide-induced alveolar bone resoption2007
- Author(s)
  Chen R, Kanzaki H, Chiba M, Nishimura M, Kanzaki R, Igarashi K.
- Journal Title
  
  J Periodontal Res 43(2)
  
  Pages: 237-245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local osteoprotegerin gene transfer to periodontal tissue inhibits lipopolysaccharide-induced alveolar bone resorption.2007
- Author(s)
  Chen R, Kanzaki H, Chiba M, Nishimura M, Kanzaki R, Igarashi K.
- Journal Title
  
  J Periodontal Res 43(2):
  
  Pages: 237-245
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Clodronate inhibits PGE(2) production in compressed periodontal ligament cells.2006
- Author(s)
  Liu L, Igarashi K, Kanzaki H, Chiba M, Shinoda H, Mitani H.
- Journal Title
  
  J Dent Res 85(8):
  
  Pages: 757-760
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Clodronate inhibits PGE(2) production in compressed periodontal ligament cells.2006
- Author(s)
  Liu L, Igarashi K, Kanzaki H, Chiba M, Shinoda H, Mitani H
- Journal Title
  
  J Dent Res 85・8
  
  Pages: 757-760
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement2006
- Author(s)
  Kanzaki H
- Journal Title
  
  Gene Therapy 13・8
  
  Pages: 678-685
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] メカニカルストレス受容歯根膜細胞による破骨細胞分化誘導制御2006
- Author(s)
  千葉美麗, 菅崎弘幸, 松本千登勢, 糖塚世毅
- Journal Title
  
  日本実験力学会講演論文集 6
  
  Pages: 151-153
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Cyclical tensile force on periodontal ligament cells inhibits osteoclastogenesis through OPG induction2006
- Author(s)
  Kanzaki H, Chiba M, Sato A, Miyagawa A, Arai K, Nukatsuka S, Mitani H.
- Journal Title
  
  J Dent Res 85(5):
  
  Pages: 457-462
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement2006
- Author(s)
  Kanzaki H, Chiba M, Arai K, Takahashi I, Haruyama N, Nishimura M, Mitani H.
- Journal Title
  
  Gene Ther 13(8)
  
  Pages: 678-685
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local RANHL gene transfer to the periodontal tissue accelerates orthodontic tooth movement.2006
- Author(s)
  Kanzaki H, Chiba M, Arai K, Takahashi I, Haruyama N, Nishimura M, Mitani H.
- Journal Title
  
  Gene Ther. ;13(8):
  
  Pages: 678-685
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Cyclical tensile force on periodontal ligament cells inhibits osteoclastogenesis through OPG induction.2006
- Author(s)
  Kanzaki H, Chiba M, Sato A, Miyagawa A, Arai K, Nukatsuka S, Mitani H
- Journal Title
  
  J Dent Res 85・5
  
  Pages: 457-462
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Clodronate inhibits PGE(2) production in compressed periodontal liament cells2006
- Author(s)
  Liu L, Igarashi K, Kanzaki H, Chiba M, Shinoda H, Mitani H.
- Journal Title
  
  J Dent Res 85(8)
  
  Pages: 757-760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement.2006
- Author(s)
  Kanzaki H, Chiba M, Arai K, Takahashi I, Haruyama N, Nishimura M, Mitani H
- Journal Title
  
  Gene Ther 13・8
  
  Pages: 678-685
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Tension to PDL inhibited OC-genesis through OPG induction2006
- Author(s)
  Kanzaki H
- Journal Title
  
  Journal of Dental Research (印刷中)
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Cyclical tensile for ce on periodontal ligameng cells inhibits osteoclastogenesis through OPG induction2006
- Author(s)
  Kanzaki H, Chiba M, Sato A, Miyagawa A, Arai K, Nukatsuka S, Mitani H.
- Journal Title
  
  J Dent Res 85(5)
  
  Pages: 457-462
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local OPG gene transfer to periodontal tissue inhibits orthodontic tooth movement.2004
- Author(s)
  Kanzaki H, Chiba M, Takahashi I, Haruyama N, Nishimura M, Mitani H.
- Journal Title
  
  J Dent Res 83(12):
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local OPG gene transfer to periodontal tissue inhibits orthodontic tooth movement2004
- Author(s)
  H.Kanzaki
- Journal Title
  
  Journal of Dental Research 83
  
  Pages: 920-925
- Data Source
  KAKENHI-PROJECT-16390602
[Journal Article] Local OPG gene transfer to periodontal tissue inhibits orthodontic tooth movement2004
- Author(s)
  Kanzaki H, Chiba M, Takahashi I, Haruyama N, Nishimura M, Mitani H.
- Journal Title
  
  J Dent res 83(12)
  
  Pages: 920-925
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Patent] TACEペプチドエピトープ、抗ヒトTACEタンパク質抗体及び当該抗体を産生するハイブリドーマ2014
- Inventor(s)
  菅崎弘幸
- Industrial Property Rights Holder
  東北大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-03-25
- Overseas
- Data Source
  KAKENHI-PROJECT-23689081
[Patent] ＴＡＣＥペプチドエピトープ、抗ヒトＴＡＣＥタンパク質抗体及び当該抗体を産生するハイブリドーマ2014
- Inventor(s)
  菅崎弘幸
- Industrial Property Rights Holder
  東北大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-03-25
- Overseas
- Data Source
  KAKENHI-PROJECT-23689081
[Patent] TACEペプチドエピトープ、抗ヒトTACEタンパク質抗体及び当該抗体を産生するハイブリドーマ2013
- Inventor(s)
  菅崎弘幸
- Industrial Property Rights Holder
  菅崎弘幸
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23689081
[Patent] 細胞膜透遃性ペプチドによる破骨細胞活性阻害2013
- Inventor(s)
  菅崎弘幸
- Industrial Property Rights Holder
  東北大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-204248
- Filing Date
  2013-09-30
- Overseas
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] 全エクソーム解析を用いた希少疾患「MCHDF」責任遺伝子候補の同定 Identification of candidate responsible genes for the rare disease MCHDF using whole exome analysis2023
- Author(s)
  狩谷千尋、菅崎弘幸、伊藤由美、里村一人、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10257
[Presentation] 下顎頭軟骨における抗酸化酵素発現の低下はエピジェネティックに制御される2023
- Author(s)
  下山美保、菅崎弘幸、井田知美、真瀬崇吾、遠山俊之介、勝又裕太、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 全エクソーム解析を用いた希少疾患「MCHDF」責任遺伝子候補の同定2023
- Author(s)
  狩谷千尋、菅崎弘幸、伊藤由美、里村一人、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] DC/TMD I軸診断と口腔機能、顎顔面形態、口腔パラファンクションの関連性の検討2023
- Author(s)
  米今眞梨、菅崎弘幸、吉田佳奈、久保麟太郎、小林史卓、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 下顎頭軟骨における抗酸化酵素発現の低下はエピジェネティックに制御される2023
- Author(s)
  下山美保、菅崎弘幸、井田知美、真瀬崇吾、遠山俊之介、勝又裕太、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10256
[Presentation] 全エクソーム解析を用いた希少疾患「MCHDF」責任遺伝子候補の同定 Identification of candidate responsible genes for the rare disease MCHDF using whole exome analysis2023
- Author(s)
  狩谷千尋、菅崎弘幸、伊藤由美、里村一人、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10281
[Presentation] 骨格性下顎前突症患者における認知機能の術前矯正中推移2023
- Author(s)
  稲川侑里、菅崎弘幸、狩谷千尋、吉田佳奈、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09449
[Presentation] 全エクソーム解析を用いた希少疾患「MCHDF」責任遺伝子候補の同定 Identification of candidate responsible genes for the rare disease MCHDF using whole exome analysis2023
- Author(s)
  狩谷千尋、菅崎弘幸、伊藤由美、里村一人、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10256
[Presentation] 全エクソーム解析を用いた希少疾患「MCHDF」責任遺伝子候補の同定 Identification of candidate responsible genes for the rare disease MCHDF using whole exome analysis2023
- Author(s)
  狩谷千尋、菅崎弘幸、伊藤由美、里村一人、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10197
[Presentation] 骨格性下顎前突症患者における認知機能の術前矯正中推移2023
- Author(s)
  稲川侑里、菅崎弘幸、狩谷千尋、吉田佳奈、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 下顎頭軟骨における抗酸化酵素発現の低下はエピジェネティックに制御される2023
- Author(s)
  下山美保、菅崎弘幸、井田知美、真瀬崇吾、遠山俊之介、勝又裕太、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10281
[Presentation] 不正咬合と脳血流の関連2023
- Author(s)
  菅崎弘幸
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09449
[Presentation] 不正咬合の重症度と口腔機能の関連性について2023
- Author(s)
  佐々木耀史，菅崎弘幸，新保雄大，片山まお，溝上基一郎，野村義明，友成　博
- Organizer
  第82回東京矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 下顎頭軟骨における抗酸化酵素発現の低下はエピジェネティックに制御される2023
- Author(s)
  下山美保、菅崎弘幸、井田知美、真瀬崇吾、遠山俊之介、勝又裕太、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-22K10257
[Presentation] 下顎頭軟骨における抗酸化酵素発現の低下はエピジェネティックに制御される2023
- Author(s)
  下山美保、菅崎弘幸、井田知美、真瀬崇吾、遠山俊之介、勝又裕太、友成博
- Organizer
  第82回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10197
[Presentation] 口腔機能は不正咬合の重症度と関連している2022
- Author(s)
  山本惇一、菅崎弘幸、佐々木耀司、関谷利子、宮本豊、小林史卓、西田倫子、友成博
- Organizer
  第81回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 骨格性下顎前突症患者の咀嚼時脳血流上昇は正常咬合者よりも低い2022
- Author(s)
  中村浩昭, 菅崎弘幸, 山田祐子, 村上真澄, 小澤絵里香, 狩谷千尋, 佐原早彩, 和田悟史, 及川崇, 友成博
- Organizer
  第32回　日本顎変形症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10218
[Presentation] 破骨細胞抑制能および抗炎症性における高濃度EGCG徐放gelの有用性2022
- Author(s)
  勝又裕太、菅崎弘幸、本田義和、田中和成、和田悟史、遠山俊之介、田中健、井田知美、下山美保、友成博
- Organizer
  第81回日本矯正歯科学会学術大会＆第9回日韓ジョイントシンポジウム
- Data Source
  KAKENHI-PROJECT-21K10197
[Presentation] 破骨細胞抑制能および抗炎症性における高濃度EGCG徐放gelの有用性2022
- Author(s)
  勝又裕太、菅崎弘幸、本田義和、田中和成、和田悟史、遠山俊之介、田中健、井田知美、下山美保、友成博
- Organizer
  第81回日本矯正歯科学会学術大会＆第9回日韓ジョイントシンポジウム
- Data Source
  KAKENHI-PROJECT-21K10199
[Presentation] 破骨細胞抑制能および抗炎症性における高濃度EGCG徐放gelの有用性2022
- Author(s)
  勝又裕太、菅崎弘幸、本田義和、田中和成、和田悟史、遠山俊之介、田中健、井田知美、下山美保、友成博
- Organizer
  第81回日本矯正歯科学会学術大会＆第9回日韓ジョイントシンポジウム
- Data Source
  KAKENHI-PROJECT-22K10281
[Presentation] C呼気試験による胃排出能と口腔機能パラメーターとの関連2022
- Author(s)
  力武春菜、菅崎弘幸、及川崇、小林史卓、佐々木耀司、溝上基一郎、山本惇一、関美南、友成博
- Organizer
  第81回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] Bach1阻害はNrf2活性化よりも強力に破骨細胞分化を阻害する2021
- Author(s)
  菅崎弘幸、和田悟史、田中　健、遠山俊之介、友成　博
- Organizer
  第80回日本矯正歯科学会学術大会＆第5回国際会議
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 骨格性非対称は咀嚼刺激による脳血流上昇を妨げる2021
- Author(s)
  佐原早彩、菅崎弘幸、山田祐子、村上真澄、狩谷千尋、和田悟史、友成　博
- Organizer
  第80回日本矯正歯科学会学術大会＆第5回国際会議
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 持続的および周期的伸展刺激が歯根膜線維芽細胞の遺伝子発現に与える影響2021
- Author(s)
  和田悟史、菅崎弘幸、遠山俊之介、田中　健、友成　博
- Organizer
  第80回日本矯正歯科学会学術大会＆第5回国際会議
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] 垂直性顔面骨格パターンと唾液検査システムSalivary Multi Test数値の関連2021
- Author(s)
  佐々木喬央、菅崎弘幸、及川崇、宮本豊、佐藤亜希子、熊谷千明、友成博
- Organizer
  第80回日本矯正歯科学会学術大会＆第5回国際会議
- Data Source
  KAKENHI-PROJECT-20K10218
[Presentation] 垂直性顔面骨格パターンと唾液検査システムSalivary Multi Test数値の関連2021
- Author(s)
  佐々木喬央、菅崎弘幸、及川　崇、宮本　豊、佐藤亜希子、熊谷千明、友成　博
- Organizer
  第80回日本矯正歯科学会学術大会＆第5回国際会議
- Data Source
  KAKENHI-PROJECT-20K10238
[Presentation] "抗酸化ストレスのエピジェネティック制御における下顎頭軟骨の特異性口唇形態変化"2019
- Author(s)
  勝又　裕太、菅崎　弘幸、宮本　豊、山口　祐希、中村　芳樹、友成　博
- Organizer
  第78回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05552
[Presentation] 矯正学的歯の移動とHMGB1　アップデートシンポジウム5「核内タンパク質HMGB1」2017
- Author(s)
  菅崎弘幸、中村芳樹
- Organizer
  歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11376
[Presentation] MMP12は矯正学的歯の移動時の牽引側歯根膜組織における血管網再構築に重要な役割を果たしている2016
- Author(s)
  成宮　毅、和田悟史、菅崎弘幸、中村芳樹
- Organizer
  第75回日本矯正歯科学会
- Place of Presentation
  アスティ徳島(徳島県徳島市)
- Year and Date
  2016-11-07
- Data Source
  KAKENHI-PROJECT-15K11356
[Presentation] Asporinは咬合機能低下に伴う新生歯槽骨添加における制御因子である2016
- Author(s)
  糸日谷佳菜子、菅崎弘幸、石川美佐緒、下田信治、中村芳樹
- Organizer
  第75回日本矯正歯科学会
- Place of Presentation
  アスティ徳島(徳島県徳島市)
- Year and Date
  2016-11-07
- Data Source
  KAKENHI-PROJECT-15K11356
[Presentation] マウスへのmyo-inositol　栄養補充による下顎骨の成長促進2016
- Author(s)
  山口祐樹、菅崎弘幸、宮本　豊、糸日谷佳菜子、深谷紗吏、勝又裕太、中村芳樹
- Organizer
  第75回日本矯正歯科学会
- Place of Presentation
  アスティ徳島(徳島県徳島市)
- Year and Date
  2016-11-07
- Data Source
  KAKENHI-PROJECT-15K11356
[Presentation] Bach1 nuclear export attenuates osteoclastogenesis and osteoclast activation via inhibition of intracellular ROS signaling.2015
- Author(s)
  Hiroyuki Kanzaki, Fumiaki Shinohara, Masazumi Matsuzawa, and Yoshiki Nakamura
- Organizer
  American Society for Bone and Mineral Research 2015 Annual Meeting
- Place of Presentation
  Washington State Convention Centor, Seattle, Washington, USA
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11356
[Presentation] Asporinは咬合機能低下に伴う歯根膜腔狭窄の制御因子である2015
- Author(s)
  糸日谷　佳菜子、菅崎　弘幸、石川　美佐緒、下田　信治、中村　芳樹
- Organizer
  第74回日本矯正歯科学会
- Place of Presentation
  福岡国際会議場(福岡市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K11356
[Presentation] IGF-1の顎関節局所投与による下顎骨非対称に対する治療の可能性2015
- Author(s)
  深谷紗吏　菅崎弘幸　宮本　豊　山口祐希　中村芳樹
- Organizer
  第74回日本矯正歯科学会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K11356
[Presentation] Nrf2を介した抗郿化ストレス都素群発現は破骨細胞分化を負に制御する2014
- Author(s)
  菅崎弘幸、篠原文明、加治屋幹人
- Organizer
  第35回東北骨代謝・骨粗鬆症研究会
- Place of Presentation
  仙台
- Year and Date
  2014-02-01
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] 細胞膜透遃性ペプチド7R-ETGEによる骨破壊性疾患の阻止2014
- Author(s)
  菅崎弘幸、篠原文明、加治屋幹人、小玉哲也
- Organizer
  第26回バイオエンジニアリング講演会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] 細胞膜透過性ペプチド7R-ETGEによる骨破壊性疾患の阻止2014
- Author(s)
  菅崎弘幸、篠原文明、加治屋幹人、小玉哲也
- Organizer
  第26回バイオエンジニアリング講演会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] Nrf2を介した抗酸化ストレス酵素群発現は破骨細胞分化を負に制御する2014
- Author(s)
  菅崎弘幸、篠原文明、加治屋幹人
- Organizer
  第35回東北骨代謝・骨粗鬆症研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] Nrf2 negatively regulates osteoclast differentiation.2012
- Author(s)
  H Kanzaki, M Kajiya, T Kodama
- Organizer
  国際歯科研究学会
- Place of Presentation
  フォスドイグアス、ブラジル
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] TNF-alpha converting enzyme degradates interferon-gamma2012
- Author(s)
  Hiroyuki Kanzaki, Mirei Chiba, Maiko Suzuki, Toshi Kawai, and Martin Taubman
- Organizer
  アメリカ免疫学会
- Place of Presentation
  ボストン(アメリカ合衆国)
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] Nrf2 negatively regulates osteoclast differentiation2012
- Author(s)
  Hiroyuki Kanzaki, Mikihito Kajiya, and Tetsuya Kodama
- Organizer
  国際歯科研究学会
- Place of Presentation
  フォスドイグアス(ブラジル)
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] TNF-alpha Converting Enzyme Degradates Interferon-Gamma.2012
- Author(s)
  Hiroyuki Kanzaki, Mirei Chiba, Maiko Suzuki, Toshi Kawai, and Martin Taubman
- Organizer
  アメリカ免疫学会
- Place of Presentation
  ボストン、アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-23689081
[Presentation] LPS Induces Alveolar Bone Resorption by Stimulating RANKL Expression2007
- Author(s)
  R. CHEN, M. CHIBA, H. KANZAKI, and K. IGARASHI
- Organizer
  The IADR/AADR/CADR 85th General Session and Exhibition
- Place of Presentation
  New Orleans, LA, USA.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] LPS Induces Alveolar Bone Resorption by Stimulating RANKL Expression2007
- Author(s)
  R. CHEN, M. CHIBA, H. KANZAKI, and K. IGARASHI
- Organizer
  The IADR/AADR/CADR 85th General Session and Exhibition
- Place of Presentation
  New Orleans, LA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] 歯周組織のリモデリングを制御する歯根膜細胞のバイオメカニクス2007
- Author(s)
  千葉美麗, 五賀優子, 菅崎弘幸, 山本照子
- Organizer
  第46回日本生体医工学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2007-04-25
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] TACE regulate inert-osteoclastogenesis in tensile-side of orthodontic-tooth-movement by RANKL-modification2006
- Author(s)
  H. KANZAKI, M. CHIBA, and K. ARAI
- Organizer
  The IADR 84th General Session & Exhibition
- Place of Presentation
  Brisbane, Australia
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] Retentive effects of local OPG-gene transfer on tooth movement2006
- Author(s)
  K. ARAI, KANZAKI, and M. CHIBA
- Organizer
  The IADR 84th General Session & Exhibition
- Place of Presentation
  Brisbane, Australia
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] Retentive effects of local OPG-gene transfer on tooth movement2006
- Author(s)
  K. ARAI, KANZAKI, and M. CHIBA
- Organizer
  The IADR General Session & Exhibition
- Place of Presentation
  Brisbane, Australia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] TACE regulated inert-osteoclastogenesis in tensile-side of orthodontic-tooth-movement by RANKL-modification2006
- Author(s)
  H. KANZAKI, M. CHIBA, and K. ARAI
- Organizer
  The IADR General Session & Exhibition
- Place of Presentation
  Brisbane, Australia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] Mechanically stimulated periodontal ligament cells inhibit osteoclastogenesis via soluble factor (s)2005
- Author(s)
  M. CHIBA, S. NUKATSUKA and H. KANZAKI
- Organizer
  The IADR/AADR/CADR 83rd General Session & Exhibition
- Place of Presentation
  Baltimore, MD, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] Mechanically stimulated periodontal ligament cells inhibit osteoclastogenesis via soluble factor(s)2005
- Author(s)
  M. CHIBA, S. NUKATSUKA and H. KANZAKI
- Organizer
  The IADR/AADR/CADR 83rd General Session
- Place of Presentation
  Baltimore, MD, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] In vivo site-specific gene transfer targeting periodontal ligament2005
- Author(s)
  M. CHIBA, S. TSUCHIYA, and H. KANZAKI
- Organizer
  The IADR/AADR/CADR 83rd General Session
- Place of Presentation
  Baltimore, MD, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] RANKL-sheddase Increased by Tension but not by Compression in PDL-cells2005
- Author(s)
  H. KANZAKI, M. CHIBA, and K. IGARASHI
- Organizer
  The LADR/AADR/CADR 83rd General Session & Exhibition
- Place of Presentation
  Baltimore, MD, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] In vivo site-specific gene transfer targeting periodontal ligament2005
- Author(s)
  M. CHIBA, S. TSUCHIYA, and H. KANZAKI
- Organizer
  The IADR/AADR/CADR 83rd General Session & Exhibition
- Place of Presentation
  Baltimore, MD, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] RANKL-sheddase Increased by Tension but not by Compression in PDL-cells2005
- Author(s)
  H. KANZAKI, M. CHIBA, and K. IGARASHI
- Organizer
  The IADR/AADR/CADR 83rd General Session
- Place of Presentation
  Baltimore, MD, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390602
[Presentation] Chemical Bach1 inhibition attenuates osteoclastogenesis.
- Author(s)
  Hiroyuki Kanzaki1, 2, Fumiaki Shinohara3, Masazumi Matsuzawa1, and Yoshiki Nakamura1
- Organizer
  IADR
- Place of Presentation
  Hynes Convention Center （Boston, MA, USA)
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-25670841
[Presentation] Nrf2活性化による抗酸化ストレス酵素群発現誘導は破骨細胞分化阻害を介して歯の移動を抑制する
- Author(s)
  菅崎弘幸、篠原文明、中村芳樹
- Organizer
  日本矯正歯科学会
- Place of Presentation
  幕張メッセ（千葉、幕張）
- Year and Date
  2014-10-20 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-25670841

1. 和田悟史 (20581119)

# of Collaborated Projects: 11 results

# of Collaborated Products: 20 results
2. Ishikawa Misao (90582445)

# of Collaborated Projects: 9 results

# of Collaborated Products: 8 results
3. Yoshiki Nakamura (10097321)

# of Collaborated Projects: 7 results

# of Collaborated Products: 27 results
4. 勝又裕太 (70886423)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
5. 遠山俊之介 (10908940)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
6. Tomonari Hiroshi (70398288)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
7. 宮本豊 (00633588)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
8. 及川崇 (60386919)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
9. 井田知美 (20965868)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. Noda Koji (10148059)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 新井千博 (10460221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 成宮毅 (00803074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. 千葉伸太郎 (40236815)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 須藤智省 (80782680)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 下山美保 (10965122)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. SHINOHARA Fumiaki (80400258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. CHIBA Mirei (10236820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
18. IGARASHI Kaoru (70202851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
19. 高野吉郎 (90126425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 下田信治 (30139620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 伊藤愛子 (70846401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 小寺稜 (80823715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 熊澤正雄 (10771743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 狩谷千尋 (10965867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 長崎健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KANZAKI Hiroyuki 菅崎 弘幸

Research Projects

Research Products

Co-Researchers

Does myo-inositol inhibit osteoclastogenesis via augmentation of Nrf2-mediated anti-oxidationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inhibition of abnormal calcification by augmented ENPP1 via Nrf2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenetic control of the anti-oxidative stress tolerance in the specificity of the condylar cartilagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

KANZAKI Hiroyuki 菅崎弘幸