Imai Jun 今井純

… Alternative Names

Jun Imai 今井純

IMAI Jun 今井純

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Researcher Number	30342918
Other IDs
External Links
Affiliation (Current)	2026: 高崎健康福祉大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2026: 高崎健康福祉大学, 薬学部, 准教授 2005 – 2006: 慶應義塾大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 08030:Family and consumer sciences, and culture and living-related / Cell biology Except Principal Investigator Basic Section 38050:Food sciences-related
Keywords	Principal Investigator 樹状細胞 / ユビキチン化 / epigallocatechin gallate / K48ユビキチン鎖 / タンパク質の品質管理機構 / アミロイドβ / パーキンソン病 / K48Ub鎖の蓄積 / 酸性化 / endosome … More / EGCG / アルツハイマー病 / 神経細胞死 / Aβ42 / Th分化 / 酒粕 / アレルギー性疾患 / Th状態 / スクリーニング / ユビキチン / 有用菌 / 抗アレルギー効果 / Thバランス / 腸内細菌叢 / 自然免疫 / アレルギー / 免疫バランス / 発酵食品 / 有用細菌 / tranlocon / the ubiquitin-protesome system / in vitro antigen processing system / ERAD / cross-presentation / dendritic cell / ユビキチン・プロテアソー / クロスプレゼンテーショ / ユビチキン・プロテアソーム / トランスロコン / ユビキチン・プロテアソーム / in vitro再構成系 / ERAD様分解 / クロスプレゼンテーション … More Except Principal Investigator 活性酸素 / 酸化ストレス / 抗酸化物質 / エルゴチオネイン / 炎症 / トランスジェニックマウス / 遺伝子改変マウス / 加齢関連疾患 / 細胞老化 / ヒドロキシラジカル / 活性酸素種 Less

レンギョウ由来のトリテルペン酸によるアルツハイマー病の予防法・根治療法の開発Principal Investigator
- Principal Investigator
  
  今井純
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Takasaki University of Health and Welfare
Elucidation of the mechanism by the ergothioneine inhibits NASH
- Principal Investigator
  
  坂井隆浩
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Takasaki University of Health and Welfare
エピガロカテキンガレートの潜伏期のアルツハイマー病に対する効果の検証と解析Principal Investigator
- Principal Investigator
  
  今井純
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Takasaki University of Health and Welfare
エルゴチオネインが細胞老化を抑制する機序の解明
- Principal Investigator
  
  坂井隆浩
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Takasaki University of Health and Welfare
Identification of the effective microorganism groups from sake lees by using the antigen presentation ability of dendritic cellsPrincipal Investigator
- Principal Investigator
  
  Jun Imai
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Takasaki University of Health and Welfare
Development and application of ergothioneine biosynthetic transgenic mice
- Principal Investigator
  
  Sakai Takahiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Takasaki University of Health and Welfare
Analysis of the transport pathway of exogenous antigens in cross-presentation by dendritic cellsPrincipal Investigator
- Principal Investigator
  
  IMAI Jun
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Keio University

All 2025 2021 2020 2019 2007 2005

All Journal Article Patent

[Journal Article] Detection of beneficial anti-allergy microbes by dendritic cells.2021
- Author(s)
  Imai J, Koike E, Sakai T.
- Journal Title
  
  The Allergy in Practice.
  
  Volume: 41 Pages: 1787-1792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K02336
[Journal Article] Endoplasmic Reticulum-Associated Degradation-Dependent Processing in Cross-Presentation and Its Potential for Dendritic Cell Vaccinations2020
- Author(s)
  Jun Imai, Mayu Otani, Takahiro Sakai
- Journal Title
  
  Pharmaceutics
  
  Volume: 12 Issue: 2 Pages: 153-153
- DOI
  10.3390/pharmaceutics12020153
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05537, KAKENHI-PROJECT-19K02336
[Journal Article] Detection of beneficial anti-allergy microbes by dendritic cells.2020
- Author(s)
  Imai J, Koike E, Sakai T
- Journal Title
  
  The Allergy in Practice
  
  Volume: 40 Pages: 829-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K02336
[Journal Article] Dendritic cells as a detecting unit for beneficial anti-allergy microbes.2020
- Author(s)
  Imai J, Koganezawa Y, Sakai T
- Journal Title
  
  The Allergy in Practice
  
  Volume: 40 Pages: 13-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K02336
[Journal Article] Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation2019
- Author(s)
  Jun Imai, Sayaka Ohashi, Takahiro Sakai
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 22 Pages: 5606-5606
- DOI
  10.3390/ijms20225606
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05537, KAKENHI-PROJECT-19K02336
[Journal Article] An optical and noninvasive method to detect the accumulation of ubiquitin chains2019
- Author(s)
  Jun Imai , Yuuta Koganezawa, Haruka Tuzuki, Ikumi Ishikawa, Takahiro Sakai
- Journal Title
  
  Cell Biology International
  
  Volume: 43 Issue: 12 Pages: 1393-1406
- DOI
  10.1002/cbin.11186
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05537, KAKENHI-PROJECT-19K02336
[Journal Article] 樹状細胞におけるクロスプレゼンテーションとERAD関連領域の新知見2007
- Author(s)
  今井純, 矢原一郎
- Journal Title
  
  Annual Review 2007免疫
  
  Pages: 70-80
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570164
[Journal Article] Mechanism of exogenous antigen presentation onto MHC class I2007
- Author(s)
  Imai J, Yahara I
- Journal Title
  
  Clinical Immunology and Allergology 47
  
  Pages: 143-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570164
[Journal Article] 外来性抗原のMHCクラスIによる提示の機序2007
- Author(s)
  今井純, 矢原一郎
- Journal Title
  
  臨床免疫・アレルギー科 47
  
  Pages: 143-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570164
[Journal Article] jyujyousaibou ni yoru cross-presentation to ERAD ni kannsuru shinnchikenn2007
- Author(s)
  Imai J, Yahara I
- Journal Title
  
  Annual Review Menneki
  
  Pages: 70-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570164
[Journal Article] Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells.2005
- Author(s)
  Imai J, Hasegawa H, Maruya M, Koyasu S, Yahara I
- Journal Title
  
  International Immunology 17
  
  Pages: 43-53
- NAID
  10014258494
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570164
[Journal Article] Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells2005
- Author(s)
  Imai J, Hasegawa H, Maruya M, Koyasu S, Yahara I
- Journal Title
  
  International Immunology 17
  
  Pages: 43-53
- NAID
  10014258494
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570164
[Patent] MHCクラスI分子と結合し、がん細胞の表面に表出される抗原ペプチドの抗原提示効率をポリペプチド鎖の伸長阻害によって向上させる方法2025
- Inventor(s)
  今井　純、坂井　隆浩
- Industrial Property Rights Holder
  今井　純、坂井　隆浩
- Industrial Property Rights Type
  特許
- Filing Date
  2025
- Data Source
  KAKENHI-PROJECT-23K05117
[Patent] 樹状細胞において抗原提示されやすいタンパク質の選択方法2005
- Inventor(s)
  今井純, 丸谷美香子, 長谷川洋典, 小安重夫, 矢原一郎
- Industrial Property Rights Holder
  慶應義塾, (株)医学生物学研究所
- Industrial Property Number
  2006-532002
- Filing Date
  2005-09-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570164
[Patent] CTL誘導能を獲得した樹状細胞の製造方法2005
- Inventor(s)
  今井純, 丸谷美香子, 長谷川洋典, 小安重夫, 矢原一郎
- Industrial Property Rights Holder
  慶應義塾, (株)医学生物学研究所
- Industrial Property Number
  2006-532003
- Filing Date
  2005-09-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570164

1. Sakai Takahiro (10418618)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results

Imai Jun 今井 純

Jun Imai 今井 純

IMAI Jun 今井 純

Research Projects

Research Products

Co-Researchers

レンギョウ由来のトリテルペン酸によるアルツハイマー病の予防法・根治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism by the ergothioneine inhibits NASH

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エピガロカテキンガレートの潜伏期のアルツハイマー病に対する効果の検証と解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エルゴチオネインが細胞老化を抑制する機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the effective microorganism groups from sake lees by using the antigen presentation ability of dendritic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and application of ergothioneine biosynthetic transgenic mice

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the transport pathway of exogenous antigens in cross-presentation by dendritic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Detection of beneficial anti-allergy microbes by dendritic cells.2021

Author(s)

Journal Title

Data Source

[Journal Article] Endoplasmic Reticulum-Associated Degradation-Dependent Processing in Cross-Presentation and Its Potential for Dendritic Cell Vaccinations2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of beneficial anti-allergy microbes by dendritic cells.2020

Author(s)

Journal Title

Data Source

[Journal Article] Dendritic cells as a detecting unit for beneficial anti-allergy microbes.2020

Author(s)

Journal Title

Data Source

[Journal Article] Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An optical and noninvasive method to detect the accumulation of ubiquitin chains2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 樹状細胞におけるクロスプレゼンテーションとERAD関連領域の新知見2007

Author(s)

Journal Title

Description

Data Source

Imai Jun 今井純

Jun Imai 今井純

IMAI Jun 今井純