TANAKA Motoyoshi 田中基幹

Researcher Number	30347562
Other IDs
External Links
Affiliation *help	2010 : 近畿大学, 医学部, 講師 2005 – 2008 : 近畿大学, 医学部, 講師 2005 : 奈良県立医科大学, 医学部, 学内講師 2004 : 奈良医科大学, 医学部, 講師 2004 : 奈良県立医科大学, 医学部, 助手 2004 : Nana Medical Univ., Dept.of Urology, Instructor, 医学部・泌尿器科学, 助手 2003 : 奈良県立医科大学, 泌尿器科, 助手
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Urology / Experimental pathology
Keywords	Principal Investigator 前立腺癌 / 遺伝子治療 / ペプチド / 分子標的治療 / PTEN癌抑制遺伝子 / Prostate cancer / Prostate Cancer / ペプチド療法 / PTEN Tumor Suppressor Gene / gene therapy … More Except Principal Investigator ペプチドワクチン / 腎細胞癌 / CA9 / 尿路上皮癌 / NADPH oxidase / renal cell carcinoma / 腫瘍 / hALKBH-8 / 腎癌 / アポトーシス / peptide vaceine / 免疫組織化学 / 活性酸素種 / HIF-1α / CA9抗原 / VEGFR / ALKBH-8 / PDL / ペプチドワクチン療法 / EPOR / hABH-8 / 膀胱尿路上皮癌 / CA9 (Carbonic Anhydrase 9) Less

The role of human ABH-8 in urothelial carcinoma
- Principal Investigator
  
  SHIMADA Keiji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Nara Medical University
Development of tailor-madepeptide vaccines for renal eell carcinoma
- Principal Investigator
  
  UEMURA Hirotsugu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kinki University
Novel molecular therapeutic strategies in prostate cancerPrincipal Investigator
- Principal Investigator
  
  TANAKA Motoyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kinki University
Molecular Therapy Targeting PTEN-Akt Signaling Pathway in Prostate Cancer.Principal Investigator
- Principal Investigator
  
  TANAKA Motoyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kinki University
  Nara Medical University
Development new generation peptides derived from CA9 as tailar-made vaccines for renal cell carcinoma
- Principal Investigator
  
  UEMURA Hirotsugu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kinki University
Application for PTEN Gene Therapy in Prostate CancerPrincipal Investigator
- Principal Investigator
  
  TANAKA Motoyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nara Medical University School of Medicine

All 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Role of syndecan-1 (CD138) in cell survival of human urothelial carcinoma.2010
- Author(s)
  Shimada K, Nakamura M, De Velasco MA, Tanaka M, Ouji Y, Miyake M, Fujimoto K, Hirao K, Konishi N.
- Journal Title
  
  Cancer Sci. Vol.101, No.1
  
  Pages : 155-160
- Data Source
  KAKENHI-PROJECT-21790392
[Journal Article] A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.2009
- Author(s)
  Shimada K, Nakamura M, Anai S, De Velasco M, Tanaka M, Tsujikawa K, Ouji Y, Konishi N.
- Journal Title
  
  Cancer Res. Vol.69, No.7
  
  Pages : 3157-3164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790392
[Journal Article] PTEN-Knockout Prostate Cancer as a Model for Experimental Immunotherapy2009
- Author(s)
  Haga, K., Tomioka, A., Liao, C. P., Kimura, T., Matsumoto, H., Ohno, I., Hermann; K., Logg, C.R., Tanaka, Hirao, Y., Hong Wu, H., Kruse, C. A., Roy-Burman, P., Kasahara, N.
- Journal Title
  
  Journal of Urology 181
  
  Pages : 354-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591876
[Journal Article] Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation2008
- Author(s)
  Tomioka A., Tanaka M., De Velasco M. Uemura H, 他7名
- Journal Title
  
  Mol Cancer Ther 7
  
  Pages : 1864-1870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390419
[Journal Article] GFP image analysis in the mouse orthotopic bladder cancer model2008
- Author(s)
  De Velasco M., Tanaka M., Uemura H, 他3名
- Journal Title
  
  Oncol Rep 20
  
  Pages : 537-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390419
[Journal Article] Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation2008
- Author(s)
  Tomioka, A., Tanaka, M., DeVelasco, M. Anai, S., Takada, S., Kushibiki, T., Tabata, Y., Rosser, C. J., Uemura, H., Hirao, H.
- Journal Title
  
  Molecular Cancer Therapeutics 7
  
  Pages : 1864-1870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591876
[Journal Article] GFP image analysis in the mouse orthotopic bladder cancer model2008
- Author(s)
  DeVelasco, M., Tanaka, M., Anai, S., Tomioka, A., Nishio, K., Uemura, H.
- Journal Title
  
  Oncology Report 20
  
  Pages : 537-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591876
[Journal Article] Phase I/II study of individualized peptide vaccines for HLA-A2/24 positive patients with hormone-refractory prostate cancer2008
- Author(s)
  Uemura H., Minami T., Tanaka M, 他4名
- Journal Title
  
  J. Clin. Oncol. 26
- Data Source
  KAKENHI-PROJECT-19390419
[Journal Article] c-Jun NH2 terminal kinase activation and decreased expression of mitogen-activated protein kinase phosphatase-1 play important roles in invasion and angiogenesis of urothelial carcinomas2007
- Author(s)
  Shimada, K., Nakamura, M., Ishida, E., Higuchi, T., Tanaka, M., Ota, I., Konishi, N.
- Journal Title
  
  American Journal of Pathology 171
  
  Pages : 1003-1012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591876
[Journal Article] Increased expression of cyclooxygenase-2 correlates with resistance to radiation in human prostate adenocarcinoma cells2007
- Author(s)
  Anai, S., Tanaka, M., Shiverick, K. T., Kim, W., Takada, S., Boehlein, S., Goodison, S., Mizokami, A., Rosser, C. J.
- Journal Title
  
  Journal of Urology 177
  
  Pages : 1913-1917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591876
[Journal Article] A phase I trail of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renalcell carcinoma2006
- Author(s)
  Uemura H, Fujimoto K, Tanaka M., et al.
- Journal Title
  
  Clin Cancer Res 12・6
  
  Pages : 1768-1775
- Data Source
  KAKENHI-PROJECT-16390468
[Journal Article] A phase I trail of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renal cell carcinoma2006
- Author(s)
  Uemura H., Fujimoto K., Tanaka M., et al.
- Journal Title
  
  Clin Cancer Res 12・6
  
  Pages : 1768-1775
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390468
[Journal Article] A phase l trial of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renal cell carcinoma.2006
- Author(s)
  Uemura H, Fujimoto K, Tanaka M, Yoshikawa M, Hirao Y, Uejima S, Yoshikawa K, Itoh K
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages : 1768-1775
- Data Source
  KAKENHI-PROJECT-17591697
[Journal Article] Combination of PTEN Gene Therapy and Radiation Inhibits the Growth of Human Prostate Cancer Xenografts.2006
- Author(s)
  Anai S, Goodison S, Shiverick K, Iczkowski K, Tanaka M, Rosser CJ.
- Journal Title
  
  Human Gene Therapy 17
  
  Pages : 675-684
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591697
[Journal Article] Combination of PTEN Gene Therapy and Radiation Inhibits the Growth of Human Prostate Cancer Xenografts.2006
- Author(s)
  Anai S, Goodison S, Shiverick K, Iczkowski K, Tanaka M, Rosser CJ
- Journal Title
  
  Human Gene Therapy 17
  
  Pages : 675-984
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591697
[Journal Article] A phase I trial of vaccination of CA9-derived peptides for HLA-A24-positive patients With cytokine-refractory metastatic renal cell carcinoma.2006
- Author(s)
  Uemura H, Fujimoto K, Tanaka M, Yoshikawa M, Hirao Y, Uejima S, Yoshikawa K, Itoh K
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages : 1768-1775
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591697
[Journal Article] PTEN gene therapy induces growth inhibition and increases efficacy of chemotherapy in prostate-cancer.2005
- Author(s)
  Tanaka, M., Rosser, C.J., Grossman, H.B.
- Journal Title
  
  Cancer Detection and Prevention 29
  
  Pages : 170-174
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591697
[Journal Article] A phase I trial of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renal cell carcinoma.2005
- Author(s)
  Uemura H, Fujimoto K, Tanaka M, Yoshikawa M, Hirao Y, Uejima S, Yoshikawa K, Itoh K.
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages : 1768-1775
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591697
[Journal Article] PTEN gene therapy induces growth inhibition and increases efficacy of chemotherapy in prostate cancer.2005
- Author(s)
  Tanaka, M., Rosser, C.J., Grossman, H.B.
- Journal Title
  
  Cancer Detection and Prevention 29
  
  Pages : 170-174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591697
[Journal Article] Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer.2005
- Author(s)
  Nogawa, M., Yuasa, T., Kimura, S., Tanaka, M., Kuroda, J., Sato, K., Yokota, A., Segawa, H., Toda, Y., Kageyama, S., Yoshiki, T., Okada, Y., Maekawa, T.
- Journal Title
  
  Journal of Clinical Investigation 115
  
  Pages : 978-985
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591697
[Presentation] The role of syndecan-1 (CD138) in progression of human urinary bladder cancer2009
- Author(s)
  Shimada, K., Nakamura, M., Marco A. De Velasco, Tanaka, M., Konishi, N.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21790392
[Presentation] 年齢別PSAカットオフ値および体積・年齢別生検本数ノモグラムを用いた前立腺生検の試み2009
- Author(s)
  田中宣道, 島田啓司, 他
- Organizer
  第97回日本泌尿器科学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21790392
[Presentation] PTEN機能性ペプチドによる前立腺癌治療の試み2008
- Author(s)
  田中基幹
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] 4074 PTEN functional peptide therapy in prostate cancer2008
- Author(s)
  M. Tanaka
- Organizer
  AACR Annual Meeting 2008
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] Metabolic syndrome accelerates mouse prostate cancer development2008
- Author(s)
  田中基幹
- Organizer
  第17回泌尿器分子・細胞研究会
- Place of Presentation
  東京
- Year and Date
  2008-02-16
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] A novel PTEN functional peptide therapy for prostate cancer2008
- Author(s)
  M. Tanaka
- Organizer
  The 14^<th> Annual Meeting 2008 Japan Society of Gene Therapy
- Place of Presentation
  札幌市
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] Prostate cancer mouse model derived by PTEN conditional gene targeting ; Towards pre-clinical appliocation2008
- Author(s)
  Tanaka, M
- Organizer
  The 24^<th> Annual Meeting of Urological Research Society
- Place of Presentation
  Amsterdam (Netherlands)
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] Pten gene targetingの手法を用いたマウス前立腺癌モデルとその臨床に向けた応用2008
- Author(s)
  田中基幹
- Organizer
  前立腺シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] p16 peptide therapy radiosensitizes in prostate cancer orthotopic model2008
- Author(s)
  Tanaka, M
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] Pten functional peptide therapy in prostate cancer2008
- Author(s)
  Tanaka, M
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] PTEN機能ペプチドによる前立腺癌治療への応用2008
- Author(s)
  田中基幹
- Organizer
  第96回日本泌尿器科学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] A novel PTEN functional peptide therapy for prostate cancer2008
- Author(s)
  Tanaka, M
- Organizer
  第14回日本遺伝子治療学会
- Place of Presentation
  札幌
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] Pten functional peptide therapy in prostate cancer2008
- Author(s)
  Tanaka, M
- Organizer
  The 99^<th> Annual Meeting, American Association for Cancer Research
- Place of Presentation
  San Diego (USA)
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] 表在性膀胱癌マウスモデルを用いたリポソーム化ドキソルビシンの治療効果2007
- Author(s)
  田中基幹
- Organizer
  第16回日本腎泌尿器予防医学研究会
- Place of Presentation
  大阪
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] Intravesical instillation of liposomal doxorubicin nanoparticles in mouse superficial bladder cancer2007
- Author(s)
  Tanaka, M
- Organizer
  The102^<nd> Annual Meeting, American Urological Association, Inc.
- Place of Presentation
  Anaheim (USA)
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] Intravesical treatment of liposomal doxorubicin nanoparticles in mouse orthotopic bladder cancer model2007
- Author(s)
  Tanaka, M
- Organizer
  The 98^<th> Annual Meeting, American Association for Cancer Research
- Place of Presentation
  Los Angeles USA
- Year and Date
  2007-04-15
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] The Role of PTEN Tumor Suppressor Gene in Prostate Cancer Derived by Prostate Specific Deletion of PTEN2007
- Author(s)
  Tanaka, M
- Organizer
  The 10^<th>Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Seattle USA
- Year and Date
  2007-03-30
- Data Source
  KAKENHI-PROJECT-19591876
[Presentation] The role of PTEN in carcinogenesis of mouse prostate.2007
- Author(s)
  Tanaka, M
- Organizer
  The 23^<rd> Annual Meeting of Urological Research Society, ct.
- Place of Presentation
  Napa (USA)
- Year and Date
  2007-10-27
- Data Source
  KAKENHI-PROJECT-19591876

1. UEMURA Hirotsugu (90213397)

# of Collaborated Projects : 5results

# of Collaborated Products : 10results
2. YOSHIKAWA Kazuhiro (60109759)

# of Collaborated Projects : 4results

# of Collaborated Products : 3results
3. HIRAO Yoshihiko (00133207)

# of Collaborated Projects : 4results

# of Collaborated Products : 4results
4. SHIMADA Keiji (90336850)

# of Collaborated Projects : 3results

# of Collaborated Products : 5results
5. DEVELASCO Marco (20449838)

# of Collaborated Projects : 2results

# of Collaborated Products : 5results
6. NOZAWA Masahiro (00441080)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. UEJIMA Shigeya (60213336)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. KONISHI Noboru (20145832)

# of Collaborated Projects : 2results

# of Collaborated Products : 3results
9. MINAMI Takafumi (70340809)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
10. TSUJIKAWA Kazutake (10207376)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
11. OUJI Yukiteru (50343421)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
12. FUJIMOTO Kiyohide (50264867)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
13. TANAKA Masahiro (00382292)

# of Collaborated Projects : 1results

# of Collaborated Products : 8results

TANAKA Motoyoshi 田中 基幹

Research Projects

Research Products

Co-Researchers

The role of human ABH-8 in urothelial carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of tailor-madepeptide vaccines for renal eell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel molecular therapeutic strategies in prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Therapy Targeting PTEN-Akt Signaling Pathway in Prostate Cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development new generation peptides derived from CA9 as tailar-made vaccines for renal cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application for PTEN Gene Therapy in Prostate CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Role of syndecan-1 (CD138) in cell survival of human urothelial carcinoma.2010

Author(s)

Journal Title

Data Source

[Journal Article] A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.2009

Author(s)

Journal Title

Data Source

[Journal Article] PTEN-Knockout Prostate Cancer as a Model for Experimental Immunotherapy2009

Author(s)

Journal Title

Data Source

[Journal Article] Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation2008

Author(s)

Journal Title

Data Source

[Journal Article] GFP image analysis in the mouse orthotopic bladder cancer model2008

Author(s)

Journal Title

Data Source

[Journal Article] Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation2008

Author(s)

Journal Title

Data Source

[Journal Article] GFP image analysis in the mouse orthotopic bladder cancer model2008

Author(s)

Journal Title

Data Source

[Journal Article] Phase I/II study of individualized peptide vaccines for HLA-A2/24 positive patients with hormone-refractory prostate cancer2008

Author(s)

Journal Title

Data Source

[Journal Article] c-Jun NH2 terminal kinase activation and decreased expression of mitogen-activated protein kinase phosphatase-1 play important roles in invasion and angiogenesis of urothelial carcinomas2007

Author(s)

Journal Title

Data Source

[Journal Article] Increased expression of cyclooxygenase-2 correlates with resistance to radiation in human prostate adenocarcinoma cells2007

Author(s)

Journal Title

Data Source

TANAKA Motoyoshi 田中基幹