TSUBOI Isao 壷井功

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壷井功ツボイイサオ

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Researcher Number	30350028
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2006 – 2008: 日本大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Risk sciences of radiation/Chemicals
Keywords	Except Principal Investigator ベンゼン代謝物 / ベンゼン / Ah受容体ノックアウトマウス / CYP2E1 / 細胞周期 / 遺伝子改変動物 / 造血幹細胞 / Ah受容体

Biological function of aryl hydrocarbon receptors in the hematopoietic progenitor cells with respect to a possible toxicologic mechanism
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences

All 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] Comparison of murine gene expression profiles between spontaneous and radiation- induced myelogenous leukemias : Stochastic and probabilistic expression variances in the former vs radiation-specific expression commonalities in the latter.2009
- Author(s)
  Hirabayashi Y、Tsuboi I、(6名省略)、Inoue T.
- Journal Title
  
  Exp Hematol 37
  
  Pages: 195-205
- Data Source
  KAKENHI-PROJECT-18510066
[Journal Article] Protective role of connexin 32 in steady-state hematopoiesis、regeneration state、and leukemogenesis.2007
- Author(s)
  Hirabayashi Y、Yoon BI、Tsuboi I、(5名省略)、Inoue T.
- Journal Title
  
  Exp Biol Med (Maywood) 232
  
  Pages: 700-12
- Data Source
  KAKENHI-PROJECT-18510066
[Journal Article] Membrane Channel Connexin 32 Maintains Lin(-)/c-kit (+) Hematopoietic Progenitor Cell Compartment: Analysis of the Cell Cycle.2007
- Author(s)
  Hirabayashi Y、Yoon BI、Tsuboi I、(5名省略)、Inoue T.
- Journal Title
  
  J Membr Biol 217
  
  Pages: 105-113
- Data Source
  KAKENHI-PROJECT-18510066
[Journal Article] Thioredoxin overexpression in mice、model of attenuation of oxidative stress、prevents benzene-induced hemato-lymphoid toxicity and thymic lymphoma.2006
- Author(s)
  Li GX、Hirabayashi Y、Yoon BI、Kawasaki Y、Tsuboi I、(4名省略)、Inoue T.
- Journal Title
  
  Exp Hematol 34
  
  Pages: 1687-97
- Data Source
  KAKENHI-PROJECT-18510066
[Presentation] Benzene-inhalation enhanced the incidence of hematopoietic neoplasms in p53-deficient mice with respect to strain- differences between C57BL/6 and C3H/He.2008
- Author(s)
  Hirabayashi Y、Yoon BI、Tsuboi I、(2名省略)、Inoue T
- Organizer
  Society of Toxicology 47^<th> Annual Meeting & ToxExpo
- Place of Presentation
  Seattle WA
- Year and Date
  2008-03-16
- Data Source
  KAKENHI-PROJECT-18510066
[Presentation] Role of Cx32 in steady-state hematopoiesis and leukemogenesis : study in the Cx32-knockout mice.2008
- Author(s)
  Hirabayashi Y、Yoon BI、Tsuboi I、(2名省略)、Inoue T
- Organizer
  Society of Toxicology 47^<th> Annual Meeting & ToxExpo
- Place of Presentation
  Seattle,WA
- Year and Date
  2008-03-16
- Data Source
  KAKENHI-PROJECT-18510066
[Presentation] A new toxicological biomarker, connexin 32, in the hematopoietic stem cells: the deficiency induced a prolongation of chemical damage and an increased incidence of leukemogenesis.2007
- Author(s)
  Hirabayashi Y、Yoon BI、Tsuboi I、(5名省略)、Inoue T
- Organizer
  International Congress of Toxicology XI
- Place of Presentation
  Montreal, Canada
- Year and Date
  2007-07-18
- Data Source
  KAKENHI-PROJECT-18510066

1. INOUE Tohru (50100110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. HIRABAYASHI Yoko (30291115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. YOON Byung-il

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

TSUBOI Isao 壷井 功

壷井 功 ツボイ イサオ

Research Projects

Research Products

Co-Researchers

Biological function of aryl hydrocarbon receptors in the hematopoietic progenitor cells with respect to a possible toxicologic mechanism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Comparison of murine gene expression profiles between spontaneous and radiation- induced myelogenous leukemias : Stochastic and probabilistic expression variances in the former vs radiation-specific expression commonalities in the latter.2009

Author(s)

Journal Title

Data Source

[Journal Article] Protective role of connexin 32 in steady-state hematopoiesis、regeneration state、and leukemogenesis.2007

Author(s)

Journal Title

Data Source

[Journal Article] Membrane Channel Connexin 32 Maintains Lin(-)/c-kit (+) Hematopoietic Progenitor Cell Compartment: Analysis of the Cell Cycle.2007

Author(s)

Journal Title

Data Source

[Journal Article] Thioredoxin overexpression in mice、model of attenuation of oxidative stress、prevents benzene-induced hemato-lymphoid toxicity and thymic lymphoma.2006

Author(s)

Journal Title

Data Source

[Presentation] Benzene-inhalation enhanced the incidence of hematopoietic neoplasms in p53-deficient mice with respect to strain- differences between C57BL/6 and C3H/He.2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Role of Cx32 in steady-state hematopoiesis and leukemogenesis : study in the Cx32-knockout mice.2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A new toxicological biomarker, connexin 32, in the hematopoietic stem cells: the deficiency induced a prolongation of chemical damage and an increased incidence of leukemogenesis.2007

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

TSUBOI Isao 壷井功

壷井功ツボイイサオ