Hashimoto Haruo 橋本晴夫

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HASHIMOTO Haruo 橋本晴夫

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Researcher Number	30353478
Other IDs
External Links
Affiliation (Current)	2025: 公益財団法人実中研, 教育・研修室, 室長代理
Affiliation (based on the past Project Information) *help	2025: 公益財団法人実中研, 教育・研修室, 室長代理 2020: 公益財団法人実験動物中央研究所, 教育・研修室, 主任 2018 – 2020: 公益財団法人実験動物中央研究所, 教育・研修室, 研究員 2016: 公益財団法人実験動物中央研究所, 実験動物研究部, 研究員 2012 – 2015: 公益財団法人実験動物中央研究所, その他部局等, 研究員 … More 2011: 公益財団法人実験動物中央研究所, バイオメディカル研究部, 研究員 2011: 実験動物中央研究所, バイオメディカル研究部, 研究員 2011: 実験動物中央研究所, メディカル研究部, 研究員 2011: 実験動物中央研究所, 研究部, 研究員 2010: 財団法人実験動物中央研究所, バイオメディカル研究部, 研究員 2009 – 2010: 日本獣医生命科学大学, 実験動物中央研究所, 研究員 2007: Central Institute for Experimental Animals, Animal Model laboratory, Researcher 2005 – 2006: (財)実験動物中央研究所, 実験動物研究部, 研究員 Less
Review Section/Research Field	Principal Investigator Laboratory animal science / Basic Section 62030:Learning support system-related / Basic Section 42040:Laboratory animal science-related / Laboratory animal science Except Principal Investigator Laboratory animal science / Clinical veterinary science
Keywords	Principal Investigator マウス / ES細胞 / 胚盤胞補完法 / 糖尿病 / 膵臓 / 腎臓 / shRNA / HNF-1β / 腎疾患 / インスリン … More / MODY5 / MODY2 / Prdm14 / キメラマウス / 不妊 / PRDM14 / 生殖細胞 / PDX-1 / Pｄｘ１ / Pdx1 / ヒト化肝臓マウス / アデノ随伴ウィルス / Sry遺伝子 / 雌雄生みわけ / SRY / 雌雄産み分け / 雌雄生み分け / 胚移植 / 体外受精 / 動物実験技術 / 性行動 / トランスジェニック / 繁殖行動 / プロラクチン … More Except Principal Investigator 糖尿病 / insulin resistance / translational research / strain / TRS-2 / type 2 diabetes / 自然交配 / 体外受精 / 遺伝的背景 / ノックアウトマウス / 実験動物 / PPAR / 系統 / インシュリン抵抗性 / トランスレーショナル研究 / 系統育成 / IRS-2 / 2型糖尿病 / 早期診断 / インスリン / 遺伝子 / 肥満 / 動物 Less

ハプティクス(触覚)機能を搭載した先進的動物実験技術訓練用VRコンテンツ開発Principal Investigator
- Principal Investigator
  
  橋本晴夫
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62030:Learning support system-related
- Research Institution
  Central Institute for Experimental Medicine and Life Science
Development of MODY5 model mouse using blastocyst complementationPrincipal Investigator
- Principal Investigator
  
  Hashimoto Haruo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Central Institute for Experimental Animals
Establishment of mouse blastocyst complementation without contribution to germ cellsPrincipal Investigator
- Principal Investigator
  
  Hashimoto Haruo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Establish of novel gene therapy of diabetes using Humanized liver micePrincipal Investigator
- Principal Investigator
  
  HARUO Hashimoto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Application of convenience gender-sorting of mouse spermatozoa to mouse reproductive engineering technologyPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Haruo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  実験動物中央研究所
   Central Institute for Experimental Animals
Development of early diagnosis for obesity and diabetes using insulin signaling gene expressions in dogs and cats
- Principal Investigator
  
  ARAI Toshiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
遺伝子改変動物の可逆的繁殖阻止に対する高プロラクチン血症動物の応用Principal Investigator
- Principal Investigator
  
  橋本晴夫
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Animal Experimentation system as an infrastructure to support translational progression of diabetes research to medical practice
- Principal Investigator
  
  YOSUYUKI Ohnishi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals

[Book] TYPE 1 DIABETES Complications, Pathogenesis and Alternative Treatment2011
- Author(s)
  Arai T, Mori N, Hashimoto H
- Total Pages
  470
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-21380195
[Journal Article] Expression of MCP-1 in white adipose tissues induce the resistin-hypersecretion in type 2 diabetes.2020
- Author(s)
  Haruo HASHIMOTO, Tomoo ETO, Kenji KAWAI, Toshio AKIMOTO, Kyoji HIOKI
- Journal Title
  
  Obesity Medicine
  
  Volume: 20 Pages: 100286-100290
- DOI
  10.1016/j.obmed.2020.100286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06044
[Journal Article] Development of blastocyst complementation technology without contributions to gametes and the brain2019
- Author(s)
  Haruo HASHIMOTO, Tomoo ETO, Masafumi YAMAMOTO, Mika YAGOTO, Motohito GOTO, Takahiro KAGAWA, Keisuke KOJIMA, Kenji KAWAI, Toshio AKIMOTO, Ri-ichi TAKAHASHI
- Journal Title
  
  Exp. Anim.
  
  Volume: 68 Issue: 3 Pages: 361-370
- DOI
  10.1538/expanim.18-0173
- NAID
  130007689918
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06044
[Journal Article] ビニールアイソレータへの応用を目指した宇宙服用ファスナーの気密性に関する検討2019
- Author(s)
  斎藤宗雄, 今井都泰, 冨澤政史, 橋本晴夫, 日置恭司
- Journal Title
  
  実験動物技術
  
  Volume: 54 Pages: 7-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06044
[Journal Article] 炭酸ガスを用いた減衰法による飼育ケージの換気回数の測定.2018
- Author(s)
  斎藤宗雄, 今井都秦, 冨澤政史, 橋本晴夫, 日置恭司.
- Journal Title
  
  実験動物技術
  
  Volume: 53 (2) Pages: 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06044
[Journal Article] Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.2018
- Author(s)
  Igarashi H, Uemura, M, Hiramatsu R, Hiramatsu R, Segami S, Pattarapanawan M, Hirate Y, Yoshimura Y, Hashimoto H, Higashiyama H, Sumitomo H, Kurohmaru M, Saijoh Y, Suemizu H, Kanai-Azuma M, Kanai Y.
- Journal Title
  
  Biol Reprod
  
  Volume: - Issue: 3 Pages: 578-589
- DOI
  10.1093/biolre/ioy079
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-18K06044, KAKENHI-PROJECT-18H02361, KAKENHI-PROJECT-17J11177, KAKENHI-PROJECT-17H01501, KAKENHI-PROJECT-16J40235
[Journal Article] Adiponectin deficiency-induced diabetes increases TNFα and FFA via downregulation of PPARα2018
- Author(s)
  Haruo HASHIMOTO,Masafumi YAMAMOTO, Emika SUGIURA, Hayato ABE, Takahiro KAGAWA, Ri-ichi TAKAHASHI, Toshio AKIMOTO, Hiroshi SUEMIZU.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 80 Issue: 4 Pages: 662-666
- DOI
  10.1292/jvms.17-0641
- NAID
  130006708371
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06044
[Journal Article] 集塵性能に優れた新しいビニールアイソレータ用エアフィルター材の開発及び従前フィルターとの比較.2018
- Author(s)
  斎藤宗雄, 今井都秦, 冨澤政史, 橋本晴夫, 日置恭司.
- Journal Title
  
  実験動物技術
  
  Volume: 53 (2) Pages: 75-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06044
[Journal Article] Study on AAV-mediated Gene Therapy for Diabetes in Humanized Liver Mouse to Predict Efficacy in Humans.2016
- Author(s)
  Hashimoto H, Mizushima T, Ogura T, Kagawa T, Tomiyama K, Takahashi R, Yagoto M, Kawai K, Chijiwa T, Nakamura M, Suemizu H
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 478 Issue: 3 Pages: 1254-60
- DOI
  10.1016/j.bbrc.2016.08.104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430097, KAKENHI-PROJECT-15K14374
[Journal Article] ビニールアイソレータの圧力変化を応用した空気漏洩の簡便な検出方法の確立2016
- Author(s)
  齊藤宗雄, 今井都秦, 橋本晴夫
- Journal Title
  
  実験動物技術
  
  Volume: 51 Pages: 41-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14374
[Journal Article] スンクスの嘔吐を強化する遺伝的要因は雄に存在する可能性.2015
- Author(s)
  江袋　進、橋本晴夫、冨澤政史、何　裕遥、小倉智幸、樋口裕一郎、桑畑　玲、寺
- Journal Title
  
  実験動物技術
  
  Volume: 50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500500
[Journal Article] Forced expression of PDX-1 gene makes hepatoma cells to acquire glucose-responsive insulin secretion while maintaining hepatic characteristic.2015
- Author(s)
  Haruo HASHIMOTO, Yuichiro HIGUCHI, Kenji KAWAI.
- Journal Title
  
  Cellular & Molecular Biology
  
  Volume: 61 Pages: 21-29
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500500
[Journal Article] Expressin of pancreatic and duodenal homeobox1 (PDX1) protein in the interior and exterior regions of the intestine, revealed by development and analysis of Pdx1 knockout mice.2015
- Author(s)
  Haruo HASHIMOTO, Tsutomu KAMISAKO, Takahiro KAGAWA, Seiki HARAGUCHI, Mika YAGOTO, Ri-ichi TAKAHASHI, Kenji KAWAI, Hiroshi SUEMIZU.
- Journal Title
  
  Laboratory Animal Research
  
  Volume: 31 Issue: 2 Pages: 93-98
- DOI
  10.5625/lar.2015.31.2.93
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14374
[Journal Article] スンクスの嘔吐を強化する遺伝的要因は雄に存在する可能性.2015
- Author(s)
  江袋　進, 橋本晴夫, 冨澤政史, 何　裕遙, 小倉智幸, 樋口裕一郎, 桑畑　玲, 寺田　節, 日置恭司, 高橋利一, 齋藤宗雄
- Journal Title
  
  実験動物技術
  
  Volume: 50 Pages: 11-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14374
[Journal Article] 2型糖尿病モデルIRS-2ノックアウトマウスにおける遺伝的背景、129+Ter/SvおよびC57BL/6JJcl系統の比較.2014
- Author(s)
  橋本晴夫，新井敏郎，川井健司，窪田直人，植木浩二郎，日置恭司，斎藤宗雄，大西保行，上山義人，門脇孝，伊藤守.
- Journal Title
  
  実験動物技術
  
  Volume: 49 Pages: 3-12
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500500
[Journal Article] 2型糖尿病モデルIRS-2ノックアウトマウスにおける遺伝的背景、129+Ter/SvおよびC57BL/6JJcl系統の比較2014
- Author(s)
  橋本晴夫、新井敏郎、川合健司ら
- Journal Title
  
  実験動物技術
  
  Volume: 49巻1号
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500500
[Journal Article] A versatile technique for the in vivo imaging of human tumor xenografts using near-infrared fluorochrome-conjugated macromolecule probes.2013
- Author(s)
  1. Hiroshi SUEMIZU, Kenji KAWAI, Yuichiro HIGUCHI, Haruo HASHIMOTO et al.
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500500
[Journal Article] Application of a New Convenience Gender Sorting Method for Mouse Spermatozoa to Mouse Reproductive Engineering Technology2013
- Author(s)
  Haruo HASHIMOTO, Tomoo ETO, Hiroshi SUEMIZU, Mamoru ITO
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 75 Issue: 2 Pages: 231-235
- DOI
  10.1292/jvms.12-0303
- NAID
  130001879632
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500500
[Journal Article] Study on establishment of congenic strains and screening of characteristics in IRS-2 deficient mice to support translational research on type 2 diabetes2011
- Author(s)
  Haruo Hashimoto
- Journal Title
  
  Experimental Animal
  
  Volume: 60(1) Pages: 21-32
- NAID
  10029549831
- URL
  https://www.jstage.jst.go.jp/article/expanim/60/1/60_1_1/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380195
[Journal Article] Study on establishment of congenic strains and screening of characteristics in IRS-2 deficient mice to support translational research on type 2 diabetes2011
- Author(s)
  Haruo Hashimoto
- Journal Title
  
  Experimental Animals
  
  Volume: 60(1) Pages: 21-32
- NAID
  10029549831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650095
[Journal Article] Role of resistin inferred from strain difference in B6J- and BKS.Cg-db/db mice2011
- Author(s)
  Haruo Hashimoto, et al
- Journal Title
  
  Journal of Experimental Animal Technology
  
  Volume: 46 Pages: 11-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650095
[Journal Article] db/dbマウスの系統比較から考察されるレジスチンの役割2011
- Author(s)
  橋本晴夫、新井敏郎、川井健司、鬼頭千佳、大美典子、早川絵里、水島友子、樋口裕一郎、江袋美知、末水洋志、日置恭司、斎藤宗雄、伊藤守、小坂樹徳
- Journal Title
  
  実験動物技術
  
  Volume: 46巻 Pages: 11-18
- NAID
  10029381001
- URL
  http://ci.nii.ac.jp/naid/10029381001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650095
[Journal Article] Vinyl Isolator Breeding Induces Insulin Resistance in C57BL/6JJcl Mice2011
- Author(s)
  Hashimoto, H., Suemizu, H.(15名,・12番目)
- Journal Title
  
  Exp. Anim.
  
  Volume: 60 Issue: 5 Pages: 497-508
- DOI
  10.1538/expanim.60.497
- NAID
  10029835491
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240042, KAKENHI-PROJECT-22650095
[Journal Article] Study on Establishment of Congenic Strains and Screening of Characteristics in IRS-2 Deficient Mice to Support Translational Research on Type 2 Diabetes2011
- Author(s)
  Haruo HASHIMOTO
- Journal Title
  
  Exp. Anim.
  
  Volume: 60 Issue: 1 Pages: 21-32
- DOI
  10.1538/expanim.60.21
- NAID
  10029549831
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650095
[Journal Article] Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficient mice2009
- Author(s)
  Hashimoto H, Arai T, Mori A, Kadowaki T, Kosaka K, et al
- Journal Title
  
  Experimental and Clinical Endocrinology & Diabetes 117
  
  Pages: 577-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380195
[Journal Article] An efficient reproductive method for Irs2-/-mice with C57BL/6J Jcl genetic background2008
- Author(s)
  Hashimoto, ら(他20名)
- Journal Title
  
  Experimental Animals 57
- NAID
  10024166620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] An efficient reproductive method for Irs2-/- mice with C57BL/6J Jcl genetic background2008
- Author(s)
  Hashimoto, ら(他20名)
- Journal Title
  
  Experimental animals 57巻(In press)
- NAID
  10024166620
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] 遺伝子改変による高プロラクチン血症モデルマウス開発の試み2007
- Author(s)
  橋本, ら(他8名)
- Journal Title
  
  実験動物技術 42巻
  
  Pages: 23-32
- NAID
  10021921799
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technologyare stable2007
- Author(s)
  Hashimoto, et. al.
- Journal Title
  
  Experimental animals 56
  
  Pages: 149-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007
- Author(s)
  Hashimoto et al.(他14名)
- Journal Title
  
  Experimental Animmals 56巻・2号(In press)
- NAID
  130000068045
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007
- Author(s)
  Hashimoto, ら(他14名)
- Journal Title
  
  Experimental Animals 56
  
  Pages: 149-154
- NAID
  130000068045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007
- Author(s)
  Hashimoto, ら(他14名)
- Journal Title
  
  Experimental animals 56巻
  
  Pages: 149-154
- NAID
  130000068045
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] Developments of hyperprolactinemia transgenic mice2007
- Author(s)
  Hashimoto, et. al.
- Journal Title
  
  Journal of Experimental Animal Technology 42
  
  Pages: 23-32
- NAID
  10021921799
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] 遺伝子改変による高プロラクチン血症モデルマウス開発の試み2007
- Author(s)
  橋本晴夫, 江藤智生, 上迫努, 鬼頭千佳, 川井健司, 森智惠, 日置恭司, 伊藤守, 玉置憲一
- Journal Title
  
  実験動物技術 42巻 1号(in press)
- NAID
  10021921799
- Data Source
  KAKENHI-PROJECT-17700380
[Journal Article] Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J:Jcl mice deficient in insulin receptor substrate 2.2006
- Author(s)
  Hashimoto, ら(他15名)
- Journal Title
  
  Comparative Medicine 56巻
  
  Pages: 176-187
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J : Jcl mice deficient in insulin receptor substrate 2.2006
- Author(s)
  Hashimoto, et. al.
- Journal Title
  
  Comparative Medicine 56
  
  Pages: 176-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J : Jcl mice deficient in insulin receptor substrate 22006
- Author(s)
  Hashimoto et al.(他15名)
- Journal Title
  
  Comparative Medicine 56巻・3号
  
  Pages: 176-187
- Data Source
  KAKENHI-PROJECT-17200029
[Journal Article] An efficient reproductive method for Irs2-/- mice with C57BL/6J Jcl genetic background
- Author(s)
  Hashimoto, et. al.
- Journal Title
  
  Experimental animals 57(in press)
- NAID
  10024166620
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Presentation] 発光レポーターを用いた移殖胚選抜によるトランスジェニックマーモセット作製の効率化2020
- Author(s)
  高橋司、佐藤人美、江藤智生、橋本晴夫、梅山一大、長嶋比呂志、佐々木　えりか
- Organizer
  第8回日本マーモセット研究会大会(シーサイドホテル舞子ビラ神戸)
- Data Source
  KAKENHI-PROJECT-18K06044
[Presentation] 「動物実験技術者養成講座」15年間の総括2019
- Author(s)
  冨澤政史、橋本晴夫、町田一彦、伊藤豊志雄、日置恭司、横山峯介
- Organizer
  第66回日本実験動物学会総会(福岡国際会議場/福岡県)
- Data Source
  KAKENHI-PROJECT-18K06044
[Presentation] 「動物実験」から「In vivo実験医学」へ－実中研が新たに展開する教育研修プログラムの紹介－2019
- Author(s)
  橋本晴夫、冨澤政史、日置恭司、伊藤豊志雄、横山峯介
- Organizer
  第53回日本実験動物技術者協会総会 (松山市総合コミュニティセンター/愛媛県).
- Data Source
  KAKENHI-PROJECT-18K06044
[Presentation] アディポネクチン欠損によるPPARαの発現低下を介したTNFαの増加2018
- Author(s)
  橋本晴夫、山本真史、杉浦恵美香、阿倍隼人、香川貴洋、後藤元人、高橋利一、秋元敏雄、末水洋志
- Organizer
  第65回日本実験動物学会総会(富山県民会館)
- Data Source
  KAKENHI-PROJECT-18K06044
[Presentation] C57BL/6JJclを遺伝的背景に持つIRS2欠損マウスの効率的な繁殖方法の検討2016
- Author(s)
  橋本晴夫, 江藤智生, 上迫　努, 山内敏正, 窪田直人, 植木浩二郎, 日置恭司, 齊藤宗雄, 門脇　孝, 伊藤　守
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K14374
[Presentation] マウス雌雄生みわけに関する新技法の開発2016
- Author(s)
  橋本晴夫, 江藤智生, 末水洋志, 伊藤　守
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィッコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14374
[Presentation] 2型糖尿病モデルIRS-2ノックアウトマウスにおける遺伝的背景129+Ter/SvおよびC57BL/6JJcl系統の比較2015
- Author(s)
  橋本晴夫、新井敏郎、川井健司、窪田直人、植木浩二郎、日置恭司、斎藤宗雄、大西保行、上山義人、門脇　孝、伊藤　守
- Organizer
  第 49回日本実験動物技術者協会総会(第34回日本実験動物技術者協会研究奨励賞)
- Place of Presentation
  静岡県コンベンションアーツセンター
- Year and Date
  2015-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K14374
[Presentation] PDX-1ノックアウトマウス開発の試み2015
- Author(s)
  橋本晴夫、原口清輝、上迫　努、香川貴洋、位高美香、高橋利一、川井健司、末水洋志
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K14374
[Presentation] アイソレーター飼育はC57BL/6JJclマウスにインシュリン抵抗性を引き起こす2011
- Author(s)
  橋本晴夫、江袋進、野津量子、植野昌未、新井敏郎、川井健司、平田裕、小川麻耶、水澤卓馬、末水洋志、伊藤守、齊藤宗雄、日置恭司(実中研,日獣大)
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22650095
[Presentation] 糖尿病のトランスレーショナル研究支援のためのIRS・2ノックアウトマウスの系統化と特性検索に関する研究2010
- Author(s)
  橋本晴夫
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都テレサ(京都)
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22650095
[Presentation] アイソレーター飼育はC57BL/6JJclマウスにインシュリン抵抗性を引き起こす2010
- Author(s)
  橋本晴夫
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-22650095
[Presentation] db/dbマウスの系統差から考察されるレジスチンの役割2009
- Author(s)
  橋本晴夫、川井健司、新井敏郎, 他
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-21380195
[Presentation] インスリンレセプター基質(IRS-2)ノックアウトマウスにおける肥満および2型糖尿病の発症メカニズム2006
- Author(s)
  橋本晴夫
- Organizer
  第1回学術フロンティア・ハイテクリサーチシンポジウム
- Place of Presentation
  日本獣医生命科学大学
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Presentation] Mechanism of obesity and type2 diabetes in Insulin receptor substrates 2 deficient mice2006
- Author(s)
  Hashimoto
- Organizer
  The First Symposium of the Academic Frontier & High Tech Research.
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Presentation] C57BL/6Jを遺伝的背景とするIRS-2欠損マウスの血漿代謝産物および酵素活性の加齢的特性2005
- Author(s)
  橋本, ら(他16名)
- Organizer
  第22回日本疾患モデル学会総会
- Place of Presentation
  伊香保
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Presentation] Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J : Jcl mice deficient in insulin receptor substrate 2.2005
- Author(s)
  Hashimoto, et. al.
- Organizer
  The 23rd Annual Meeting of The Japanese Society of Animal Models for Human Diseases.
- Place of Presentation
  Ikaho
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200029
[Presentation] 再生医学研究用ツールのための全身性クサビラオレンジ発現マウス開発の試み
- Author(s)
  橋本晴夫、上迫　努、山本真史、香川貴洋、川井健司、中村雅登、末水洋志
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-24500500

1. ARAI Toshiro (70184257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. HIGUCHI Yuichiro (00596281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. ISHIOKA Katsumi (60409258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YAMAMOTO Ichiro (00424763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOSUYUKI Ohnishi (70201382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIOKI Kyoji (80208735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TOBE Kazuyuki (30251242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 外丸祐介 (90309352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YUKI YOSHIMURA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOMOO ETOH

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. KENJI KAWAI

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 千々和剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 九郎丸正道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 金井克晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Haruo 橋本 晴夫

HASHIMOTO Haruo 橋本 晴夫

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ハプティクス(触覚)機能を搭載した先進的動物実験技術訓練用VRコンテンツ開発Principal Investigator

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Development of MODY5 model mouse using blastocyst complementationPrincipal Investigator

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Establishment of mouse blastocyst complementation without contribution to germ cellsPrincipal Investigator

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Establish of novel gene therapy of diabetes using Humanized liver micePrincipal Investigator

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Application of convenience gender-sorting of mouse spermatozoa to mouse reproductive engineering technologyPrincipal Investigator

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Development of early diagnosis for obesity and diabetes using insulin signaling gene expressions in dogs and cats

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遺伝子改変動物の可逆的繁殖阻止に対する高プロラクチン血症動物の応用Principal Investigator

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Animal Experimentation system as an infrastructure to support translational progression of diabetes research to medical practice

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[Book] TYPE 1 DIABETES Complications, Pathogenesis and Alternative Treatment2011

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[Journal Article] Expression of MCP-1 in white adipose tissues induce the resistin-hypersecretion in type 2 diabetes.2020

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[Journal Article] Development of blastocyst complementation technology without contributions to gametes and the brain2019

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[Journal Article] ビニールアイソレータへの応用を目指した宇宙服用ファスナーの気密性に関する検討2019

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[Journal Article] 炭酸ガスを用いた減衰法による飼育ケージの換気回数の測定.2018

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[Journal Article] Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.2018

Hashimoto Haruo 橋本晴夫

HASHIMOTO Haruo 橋本晴夫