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nonaka takashi  野中 隆

ORCIDConnect your ORCID iD *help
… Alternative Names

野中 隆  ノナカ タカシ

NONAKA Takashi  野中 隆

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Researcher Number 30356258
Other IDs
Affiliation (Current) 2025: 公益財団法人東京都医学総合研究所, 臨床医科学研究分野, プロジェクトリーダー
2025: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 副参事研究員
Affiliation (based on the past Project Information) *help 2025: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 副参事研究員
2022 – 2023: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 副参事研究員
2020 – 2022: 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 副参事研究員
2016: 公益財団法人東京都医学総合研究所, 認知症高次脳機能研究分野, 副参事研究員
2015: 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 副参事研究員 … More
2012 – 2014: 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 副参事研究員
2011: 財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 副参事研究員
2010: 財団法人東京都医学研究機構, 東京都精神医学総合研究所, 主席研究員
2008: Tokyo Metropolitan Organization for Medical Research, 東京都精神医学総合研究所, 主席研究員
2008: 財団法人東京都医学研究機構, 東京都精神医学総合研究所, 主席研究院
2007 – 2008: Tokyo Metropolitan Organization for Medical Research, 東京都精神医学総合研究所, 主席研究員
2005: (財)東京都医学研究機構, 東京都精神医学総合研究所, 研究員
2004: 財団法人東京都医学研究機構, 東京都精神医学総合研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Medium-sized Section 51:Brain sciences and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Neurochemistry/Neuropharmacology / General medical chemistry / Nerve anatomy/Neuropathology
Except Principal Investigator
Basic Section 51030:Pathophysiologic neuroscience-related / Nerve anatomy/Neuropathology / Biological Sciences
Keywords
Principal Investigator
TDP-43 / リン酸化 / 神経変性疾患 / αシヌクレイン / 前頭側頭葉変性症 / 筋萎縮性側索硬化症 / パーキンソン病 / ユビキチン / タンパク質凝集体 / ワクチン … More / カゼインキナーゼ / 凝集体 / ユビキチン化 / C末端断片 / 細胞内凝集体 / レビー小体 / 細胞モデル / 細胞内蓄積モデル / 細胞内蓄積 / 線維 … More
Except Principal Investigator
アグリソーム / TDP-43 / αシヌクレイン / ストレス顆粒 / G3BP1 / シヌクレイン / パーキンソン病 / α-シヌクレイン / Nrf2 / p62 / a-synuclein / USP10 / ROS / Parkinson's disease / プリオン / 筋萎縮性側索硬化症 / プロフィリン1 / prion / seeding / LC3 / aggresome / mutation / ALS / Profilin1 / 線維 / 断片化 / ユビキチン化 / リン酸化 / 伝播 / 構造変化 / アミロイド / タウ / 凝集阻害剤 / 線維化 Less
  • Research Projects

    (10 results)
  • Research Products

    (150 results)
  • Co-Researchers

    (15 People)
  •  アネキシンA11とTDP-43の複合型凝集体の形成機構解明と治療薬開発基盤の創出Principal Investigator

    • Principal Investigator
      野中 隆
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 51:Brain sciences and related fields
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  αシヌクレイン凝集体の立体構造に基づく新規ワクチン療法の開発Principal Investigator

    • Principal Investigator
      野中 隆
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Inhibition fo prion-like amplification of a-synuclein by aggresses

    • Principal Investigator
      Katsuragi Yoshinori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Niigata College of Nursing
      Niigata University
  •  The mechanism of cytotoxicity from ALS-linked Profilin 1 mutations

    • Principal Investigator
      TANAKA Yoshinori
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  細胞内異常タンパク質凝集体形成のメカニズムの解明Principal Investigator

    • Principal Investigator
      野中 隆
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  神経変性における細胞内TDP-43凝集体の意義の解明Principal Investigator

    • Principal Investigator
      野中 隆
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Cellular and animal models for intracellular TDP-43 aggregatesPrincipal Investigator

    • Principal Investigator
      NONAKA Takashi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      公益財団法人東京都医学総合研究所
      Tokyo Metropolitan Organization for Medical Research
  •  神経変性疾患における異常蛋白質蓄積機構の解明

    • Principal Investigator
      HASEGAWA Masato
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  A cellular model for intracellular aggregates of alpha-synnclein and tauPrincipal Investigator

    • Principal Investigator
      NONAKA Takashi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  シヌクレイノパチーにおけるα-シヌクレインのユビキチン化の意義の解明Principal Investigator

    • Principal Investigator
      野中 隆
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research

All 2023 2022 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Patent

  • [Journal Article] Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria.2023

    • Author(s)
      Chakraborty R, Nonaka T, Hasegawa M, Zurzolo C.
    • Journal Title

      Cell Death Disease

      Volume: 14 Issue: 5 Pages: 329-329

    • DOI

      10.1038/s41419-023-05835-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Journal Article] タンパク質構造異常の伝播2023

    • Author(s)
      野中隆
    • Journal Title

      実験医学

      Volume: 42 Pages: 1862-1867

    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Journal Article] Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms2022

    • Author(s)
      Hosokawa M, Masuda-Suzukake M, Shitara H, Shimozawa A, Suzuki G, Kondo H, Nonaka T, Campbell W, Arai T, Hasegawa M
    • Journal Title

      Brain

      Volume: 145 Issue: 1 Pages: 349-361

    • DOI

      10.1093/brain/awab289

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07618, KAKENHI-PROJECT-19K07860, KAKENHI-PROJECT-21K07288, KAKENHI-PROJECT-22K07362
  • [Journal Article] Casein kinase 1δ/ε phosphorylates fused in sarcoma (FUS) and ameliorates FUS-mediated neurodegeneration2022

    • Author(s)
      Kishino Yuya、Matsukawa Koji、Matsumoto Taisei、Miyazaki Ryota、Wakabayashi Tomoko、Nonaka Takashi、Kametani Fuyuki、Hasegawa Masato、Hashimoto Tadafumi、Iwatsubo Takeshi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 298 Issue: 8 Pages: 102191-102191

    • DOI

      10.1016/j.jbc.2022.102191

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07270, KAKENHI-PROJECT-22K07362, KAKENHI-PROJECT-20H00525, KAKENHI-PROJECT-22KJ0792
  • [Journal Article] Neurodegeneration in Frontotemporal Lobar Degeneration and Motor Neurone Disease associated with expansions in C9orf72 is not associated with aggregated forms of dipeptide repeat proteins.2016

    • Author(s)
      Davidson Y, Robinson AC, Troakes C, Smith B, Al-Saraj S, Shaw C, Rollinson S, Masuda-Suzukake M, Suzuki G, Nonaka T, Pickering-Brown S, Snowden JS, Hasegawa M, Mann DMA.
    • Journal Title

      Neuropathol Appl Neurobiol.

      Volume: 42 Issue: 3 Pages: 242-254

    • DOI

      10.1111/nan.12292

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26111730, KAKENHI-PROJECT-15H02356
  • [Journal Article] Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43.2016

    • Author(s)
      Nonaka T, Suzuki G, Tanaka Y, Kametani F, Hirai S, Okado H, Miyashita T, Saitoe M, Akiyama H, Masai H and Hasegawa M.
    • Journal Title

      J. Biol. Chem.

      Volume: 291 Pages: 5473-5483

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Journal Article] Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43.2016

    • Author(s)
      Nonaka T, Suzuki G, Tanaka Y, Kametani F, Hirai S, Okado H, Miyashita T, Saitoe M, Akiyama H, Masai H, Hasegawa M.
    • Journal Title

      The journal of Biological Chemistry

      Volume: 291 Issue: 11 Pages: 5473-83

    • DOI

      10.1074/jbc.m115.695379

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18370, KAKENHI-PROJECT-221S0003, KAKENHI-ORGANIZER-25115001, KAKENHI-PLANNED-25115006, KAKENHI-PROJECT-23228004, KAKENHI-PROJECT-25250010, KAKENHI-PROJECT-14J03307, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-25650014, KAKENHI-PROJECT-26251004, KAKENHI-PROJECT-26290016, KAKENHI-PROJECT-16K14569, KAKENHI-PROJECT-16K14675
  • [Journal Article] Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation.2016

    • Author(s)
      Tanaka Y, Nonaka T, Suzuki G, Kametani F, Hasegawa M.
    • Journal Title

      Human Molecular Genetics

      Volume: 25 Issue: 7 Pages: 1420-33

    • DOI

      10.1093/hmg/ddw024

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K18370, KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26111730, KAKENHI-PROJECT-23228004, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-14J03307, KAKENHI-PROJECT-16K21650
  • [Journal Article] Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau.2016

    • Author(s)
      Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DM, Iwatsubo T, Hasegawa M.
    • Journal Title

      Acta Neuropathol.

      Volume: 131(2) Issue: 2 Pages: 267-280

    • DOI

      10.1007/s00401-015-1503-3

    • NAID

      120007128537

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461733, KAKENHI-PUBLICLY-26111730, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-16H06277
  • [Journal Article] Interplay between TDP-43 and docosahexaenoic acid-treated processes in amyotrophic lateral sclerosis.2016

    • Author(s)
      Cacabelosa D, Ayalaa V, Belen Granado-Serranoa A, Jove M, Torresa P, Boadaa J, Cabre R, Ramirez-Nuneza O, Gonzaloa H, Soler-Canterob A, Carlos Enrique Serranoa J, Josep Bellmunta M, Paz Romerob M, Jose Motilvab M, Nonaka T, Hasegawa M, Ferrerd I, Pamplonaa R, and Portero-Otin M.
    • Journal Title

      Neurobiol. Dis.

      Volume: 88 Pages: 148-160

    • DOI

      10.1016/j.nbd.2016.01.007

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26111730, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356
  • [Journal Article] Templated aggregation of TDP-43 by seeding with TDP-43 peptide fibrils.2016

    • Author(s)
      Shimonaka S, Nonaka T, Suzuki G, Hisanaga SI, Hasegawa M
    • Journal Title

      J. Biol. Chem.

      Volume: 291 Pages: 8896-8907

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Journal Article] Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal lobar degeneration.2016

    • Author(s)
      Kawakami I, Kobayashi Z, Arai T, Yokota O, Nonaka T, Aoki N, Niizato K, Oshima K, Higashi S, Katsuse O, Hosokawa M, Hasegawa M, Akiyama H.
    • Journal Title

      Acta Neuropathol Commun

      Volume: 4 Issue: 1 Pages: 36-36

    • DOI

      10.1186/s40478-016-0304-9

    • NAID

      120007135517

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09822, KAKENHI-PROJECT-15K09850, KAKENHI-PUBLICLY-26111730, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-26461733, KAKENHI-PROJECT-15K19757, KAKENHI-PROJECT-26461752
  • [Journal Article] αシヌクレイン凝集体のプリオン様性質2015

    • Author(s)
      野中隆,長谷川成人
    • Journal Title

      細胞

      Volume: 47 Pages: 20-23

    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Journal Article] Extracellular association of APP and tau fibrils induces intracellular aggregate formation of tau.2015

    • Author(s)
      Takahashi M, Miyata H, Kametani F, Nonaka T, Akiyama H, Hisanaga SI, Hasegawa M.
    • Journal Title

      Acta Neuropathol.

      Volume: 129 Issue: 6 Pages: 895-907

    • DOI

      10.1007/s00401-015-1415-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26111730, KAKENHI-PLANNED-26117004, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-25290024
  • [Journal Article] Inositol Hexakisphosphate Kinase 2 Promotes Cell Death in Cells with Cytoplasmic TDP-43 Aggregation.2015

    • Author(s)
      Nagata E, Nonaka T, Moriya Y, Fujii N, Okada Y, Tsukamoto H, Itoh J, Okada C, Satoh T, Arai T, Hasegawa M, Takizawa S.
    • Journal Title

      Mol Neurobiol.

      Volume: - Issue: 8 Pages: 5377-5383

    • DOI

      10.1007/s12035-015-9470-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-26111730, KAKENHI-PROJECT-26461320, KAKENHI-PROJECT-26461733
  • [Journal Article] TDP-43の神経細胞間伝播2014

    • Author(s)
      野中隆
    • Journal Title

      医学のあゆみ

      Volume: 250 Pages: 513-515

    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Journal Article] TDP-432014

    • Author(s)
      野中隆,長谷川成人
    • Journal Title

      神経内科

      Volume: 81 Pages: 630-636

    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Journal Article] Distinct pathways leading to TDP-43-induced cellular dysfunctions.2014

    • Author(s)
      Yamashita M, Nonaka T, Hirai S, Miwa A, Okado H, Arai T, Hosokawa M, Akiyama H, Hasegawa M.
    • Journal Title

      Hum Mol Genet.

      Volume: 23 Issue: 16 Pages: 4345-56

    • DOI

      10.1093/hmg/ddu152

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-24591738, KAKENHI-PROJECT-24700370, KAKENHI-PUBLICLY-25123726, KAKENHI-PUBLICLY-26111730, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-26461733
  • [Journal Article] Differential diagnosis of amyotrophic lateral sclerosis from Guillain-Barré syndrome by quantitative determination of TDP-43 in cerebrospinal fluid.2014

    • Author(s)
      Hosokawa M, Arai T, Yamashita M, Tsuji H, Nonaka T, Masuda-Suzukake M, Tamaoka A, Hasegawa M, Akiyama H.
    • Journal Title

      Int. J. Neurosci.

      Volume: 124 Issue: 5 Pages: 344-349

    • DOI

      10.3109/00207454.2013.848440

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240050, KAKENHI-PROJECT-23700433, KAKENHI-PUBLICLY-24111556, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-24591738, KAKENHI-PUBLICLY-25110738
  • [Journal Article] 神経変性における細胞内TDP-43凝集体の意義の解明2014

    • Author(s)
      野中隆
    • Journal Title

      遺伝子医学MOOK

      Volume: 26 Pages: 67-71

    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Journal Article] 患者脳に蓄積したTDP-43のプリオン様性質2014

    • Author(s)
      野中隆,長谷川成人
    • Journal Title

      Dementia Japan

      Volume: 28 Pages: 28-34

    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Journal Article] Pathological alpha-synuclein propagates through neural networks2014

    • Author(s)
      Masuda-Suzukake M, Nonaka T, Hosokawa M, Kubo M, Shimozawa A, Akiyama H, Hasegawa M
    • Journal Title

      Acta Neuropathol Commun

      Volume: 2 Issue: 1 Pages: 88-88

    • DOI

      10.1186/preaccept-1296467154135944

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-24591738, KAKENHI-PUBLICLY-26111730, KAKENHI-PLANNED-26117005
  • [Journal Article] Reducing TDP-43 aggregation does not prevent its cytotoxicity.2013

    • Author(s)
      Liu R, Yang G, Nonaka T, Arai T, Jia W, Cynader MS.
    • Journal Title

      Acta. Neuropathol. Commun.

      Volume: 1 Issue: 1

    • DOI

      10.1186/2051-5960-1-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Journal Article] Prion-like spreading of pathological alpha-synuclein in brain.2013

    • Author(s)
      Masuda-Suzukake M, Nonaka T, Hosokawa M., Oikawa T, Arai T, Akiyama H, Mann D, Hasegawa M
    • Journal Title

      Brain

      Volume: 136 Issue: 4 Pages: 1128-38

    • DOI

      10.1093/brain/awt037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240050, KAKENHI-PROJECT-23591694, KAKENHI-PROJECT-23700433, KAKENHI-PUBLICLY-24111556, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-24591738, KAKENHI-PUBLICLY-25110738, KAKENHI-PUBLICLY-23110526
  • [Journal Article] Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.2013

    • Author(s)
      Moujalled D, James JL, Parker SJ, Lidgerwood GE, Duncan C, Meyerowitz J, Nonaka T, Hasegawa M, Kanninen KM, Grubman A, Liddell JR, Crouch PJ, White AR.
    • Journal Title

      PLoS One

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Journal Article] Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains.2013

    • Author(s)
      Nonaka T, Masuda-Suzukake M, Arai T, Hasegawa Y, Akatsu H, Obi T, Yoshida M, Murayama S, Mann DM, Akiyama H, Hasegawa M.
    • Journal Title

      Cell Rep.

      Volume: 4 Issue: 1 Pages: 124-34

    • DOI

      10.1016/j.celrep.2013.06.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240050, KAKENHI-PROJECT-23591694, KAKENHI-PROJECT-23700433, KAKENHI-PUBLICLY-24111556, KAKENHI-PROJECT-24500429, KAKENHI-PUBLICLY-25110738
  • [Journal Article] Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer’s disease brain.2013

    • Author(s)
      Dan A, Takahashi M, Masuda-Suzukake M, Kametani F, Nonaka T, Kondo H, Akiyama H, Arai T, Mann DMA, Saito Y, Hatsuta H, Murayama S, Hasegawa M.
    • Journal Title

      Acta Neuropathol. Commun.

      Volume: 1 Issue: 1 Pages: 54-54

    • DOI

      10.1186/2051-5960-1-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240050, KAKENHI-PROJECT-23700433, KAKENHI-PUBLICLY-24111556, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-24700371, KAKENHI-PUBLICLY-25110738
  • [Journal Article] Prolonged nitric oxide treatment induces tau aggregation in SH-SY5Y cells2012

    • Author(s)
      Takahashi M, Tin Y, Nonaka T, Hasegawa M, Watanabe N, and Arai T
    • Journal Title

      Neurosci. Lett

      Volume: 510 Pages: 48-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells2012

    • Author(s)
      Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H
    • Journal Title

      Sci. Transl. Med

      Volume: 4(145)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration2012

    • Author(s)
      Tsuji H, Nonaka T, Yamashita M, Suzukake M, Kametani F, Akiyama H, Mann DM, Tamaoka A, Hasegawa M
    • Journal Title

      Biochem. Biophys. Res. Comm

      Volume: 417 Pages: 116-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Methylene Blue Reduced Abnormal Tau Accumulation in P301L Tau Transgenic Mice2012

    • Author(s)
      Masato Hosokawa, Tetsuaki Arai, Masami Masuda-Suzukake, Takashi Nonaka, Makiko Yamashita, Haruhiko Akiyama, Masato Hasegawa
    • Journal Title

      PLoS ONE

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Inhibition of TDP-43 Accumulation by Bis(thiosemicarbazonato)-Copper Complexes2012

    • Author(s)
      Parker SJ, Meyerowitz J, James JL, Liddell JR, Nonaka T, Hasegawa M, Kanninen KM, Lim S, Paterson BM, Donnelly PS, Crouch PJ, White AR
    • Journal Title

      PLoS One

      Volume: 7(8)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Molecular analysis and biochemical classification of TDP-43 proteinopathy2012

    • Author(s)
      Tsuji H, Arai T, Kametani F, Nonaka T, Yamashita M, Suzukake M, Hosokawa M, Yoshida M, Hatsuta H, Takao M, Saito Y, Murayama S, Akiyama H, Hasegawa M, Mann DM, Tamaoka A
    • Journal Title

      Brain

      Volume: 135 Pages: 3380-3391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Molecular Dissection of TDP-43 Proteinopathies2011

    • Author(s)
      Hasegawa M, Nonaka T, Tsuji H, Tamaoka A, Yamashita M, Kametani F, Yoshida M, Arai T, Akiyama H
    • Journal Title

      J Mol Neurosci

      Volume: 45 Pages: 480-485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] In vitro recapitulation of aberrant protein inclusions in neurodegenerative diseases : New cellular models of neurodegenerative diseases2011

    • Author(s)
      Nonaka T, Hasegawa M
    • Journal Title

      Communicative & Integrative Biology

      Volume: 4 Pages: 501-502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress2011

    • Author(s)
      Meyerowitz J, Parker SJ, Vella LJ, Ng DC, Price KA, Liddell JR, Caragounis A, Li QX, Masters CL, Nonaka T, Hasegawa M, Bogoyevitch MA, Kanninen KM, Crouch PJ, White AR
    • Journal Title

      Mol. Neurodegener

      Volume: 6 Pages: 57-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] In vitro recapitulation of aberrant protein inclusions in neurodegenerative diseases: New cellular models of neurodegenerative diseases2011

    • Author(s)
      Nonaka T* and Hasegawa M*
    • Journal Title

      Communicative & Integrative Biology

      Volume: 4 Pages: 501-502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Seeded aggregation and toxicity of alpha-synuclein and tau: cellular models of neurodegenerative diseases2010

    • Author(s)
      Nonaka T, Watanabe ST, Iwatsubo T, Hasegawa M
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 34885-34898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Transcriptional regulation of the hypocretin/orexin gene by NR6A12010

    • Author(s)
      Tanaka S, Kodama T, Nonaka T, Toyoda H, Arai M, Fukazawa M, Honda Y, Honda M, Mignot E
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 403 Pages: 178-183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Characterization of Inhibitor-Bound alpha-Synuclein Dimer: Role of alpha-Synuclein N-Terminal Region in Dimerization and Inhibitor Binding2010

    • Author(s)
      Yamaguchi Y, Masuda M, Sasakawa H, Nonaka T, Hanashima S, Hisanaga S, Kato K, Hasegawa M
    • Journal Title

      J. Mol. Biol

      Volume: 395 Pages: 445-456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Seeded aggregation and toxicity of alpha-synuclein and tau : cellular models of neurodegenerative diseases.2010

    • Author(s)
      Nonaka T, et al
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 34885-34898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy2010

    • Author(s)
      Arai T, Hasegawa M, Nonaka T, Kametani F, Yamashita M, Hosokawa M, Niizato K, Tsuchiya K, Kobayashi Z, Ikeda K, Yoshida M, Onaya M, Fujishiro H and Akiyama H
    • Journal Title

      Neuropathol

      Volume: 30 Pages: 372-380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Journal Article] Characterization of inhibitor-bound alpha-synuclein dimer : role of alpha-synuclein N-terminal region in dimerization and inhibitor binding.2010

    • Author(s)
      Yamaguchi Y, Masuda M, Sasakawa H, Nonaka T, Hanashima S, Hisanaga SI, Kato K, Hasegawa M.
    • Journal Title

      J Mol Biol 395

      Pages: 445-456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Journal Article] Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43.2009

    • Author(s)
      Nonaka T, Kametanil F, Arai T, Akiyama H, Hasegawa M.
    • Journal Title

      Hum Mol Genet 18

      Pages: 3353-3364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Journal Article] Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.2009

    • Author(s)
      Yamashita M, Nonaka T, Arai T, Kametani F, Buchman VL, Ninkina N, Bachurin SO, Akiyama H, Goedert M, Hasegawa M.
    • Journal Title

      FEBS Lett 583

      Pages: 2419-2424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Journal Article] Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.2009

    • Author(s)
      Nonaka et al (他5名)
    • Journal Title

      FEBS Lett. 583

      Pages: 394-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Journal Article] Phosphorylated and ubiquitinated TDP-43 pathological in clusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells2009

    • Author(s)
      Nonaka, et al
    • Journal Title

      FEBS Letters 583

      Pages: 394-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Journal Article] Inhibition of alpha-synuclein fibril assembly by small molecules : Analysis using epitope-specific antibodies.2009

    • Author(s)
      Masuda M, Hasegawa M. Nonaka T, Oikawa T, Yonetani M, Yamaguchi Y, Kato K, Hisanaga S, Goedert M.
    • Journal Title

      FEBS Lett 583

      Pages: 787-791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Journal Article] Conversion of wild-type alpha -synuclein into mutant-type fibrils and its propagation in the presence of A30P mutant.2009

    • Author(s)
      Yonetani M, Nonaka T, Masuda M, Inukai Y, Oikawa T, Hisanaga SI, Hasegawa M.
    • Journal Title

      J Biol Chem 284

      Pages: 7940-7950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Journal Article] A Cellular Model To Monitor Proteasome Dysfunction by alpha-Synuclein.2009

    • Author(s)
      Nonaka T, Hasegawa M.
    • Journal Title

      Biochemistry 48

      Pages: 8014-8022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Journal Article] Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.2009

    • Author(s)
      Nonaka T, et al
    • Journal Title

      FEBS Lett 583

      Pages: 394-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Journal Article] Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-432009

    • Author(s)
      Nonaka et al (他4名)
    • Journal Title

      Hum. Mol. Genet in press

      Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Journal Article] Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein : Inplication for alpha-synucleinopathies.2007

    • Author(s)
      Nonaka et al (他9名)
    • Journal Title

      FEBS Lett 581

      Pages: 4711-4717

    • Data Source
      KAKENHI-PROJECT-19590297
  • [Journal Article] シヌクレイノパチーの基礎研究における最近の進歩2007

    • Author(s)
      野中 隆, 増田 雅美, 長谷川 成人
    • Journal Title

      Dementia Japan 21

      Pages: 8-14

    • Data Source
      KAKENHI-PROJECT-19590297
  • [Journal Article] Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein:Inplication for alpha-synucleinopathies.2007

    • Author(s)
      Nonaka, et. al
    • Journal Title

      FEBS letters 581

      Pages: 4711-4717

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Journal Article] Ubiquitination of alpha-synuclein.2005

    • Author(s)
      Nonaka T. et al.
    • Journal Title

      Biochemistry 44

      Pages: 361-368

    • Data Source
      KAKENHI-PROJECT-16700313
  • [Journal Article] Ubiquitination of alpha-synuclein.2005

    • Author(s)
      Nonaka T., et al.
    • Journal Title

      Biochemistry 44

      Pages: 361-368

    • Data Source
      KAKENHI-PROJECT-16700313
  • [Patent] 変異型の神経変性疾患関連タンパク質2022

    • Inventor(s)
      野中隆
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-071735
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Patent] フルベストラントを含む神経変性疾患の治療又は予防のための医薬組成物2013

    • Inventor(s)
      山下 万貴子; 長谷川 成人; 秋山 治彦; 野中 隆
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Filing Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Patent] ミトタンを含む神経変性疾患の治療又は予防のための医薬組成物2013

    • Inventor(s)
      山下 万貴子; 長谷川 成人; 秋山 治彦; 野中 隆
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Filing Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Patent] ニフェジピン等を含む神経変性疾患の治療及び/又は予防用医薬組成物2013

    • Inventor(s)
      山下 万貴子; 長谷川 成人; 秋山 治彦; 野中 隆
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Filing Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Patent] ブロムヘキシン塩酸塩等を含む神経変性疾患の治療及び/又は予防用医薬組成物2013

    • Inventor(s)
      山下 万貴子; 長谷川 成人; 秋山 治彦; 野中 隆
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Filing Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Patent] アモジアキンを含む神経変性疾患の治療又は予防のための医薬組成物2013

    • Inventor(s)
      山下 万貴子; 長谷川 成人; 秋山 治彦; 野中 隆
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Filing Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Patent] レチノイン酸等を含む神経変性疾患の治療及び/又は予防用医薬組成物2013

    • Inventor(s)
      山下 万貴子; 長谷川 成人; 秋山 治彦; 野中 隆
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Filing Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Patent] 神経変性疾患治療用物質のスクリーニング方法2012

    • Inventor(s)
      野中 隆,長谷川成人,増田雅美
    • Industrial Property Rights Holder
      財団法人東京都医学総合研究所
    • Acquisition Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Patent] TDP-43蓄積細胞モデル2008

    • Inventor(s)
      野中隆ら(他4名)
    • Industrial Property Rights Holder
      東京都医学研究機構
    • Industrial Property Number
      2008-101899
    • Filing Date
      2008-04-09
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] αシヌクレイン凝集体の立体構造に基づいた新規ワクチンの開発2023

    • Author(s)
      野中隆
    • Organizer
      第46回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] マウス脳や培養細胞内で生じた変異型TDP-43凝集体のシード活性の比較2023

    • Author(s)
      野中隆
    • Organizer
      第53回日本神経精神薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] リン酸化TDP-43蓄積を伴う新規マウスモデルの作製2023

    • Author(s)
      高瀬未菜、橋本雅史、大谷麗子、木村妙子、毛内拡、野中隆、長谷川成人
    • Organizer
      第42回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] 新規リン酸化FUS特異抗体の開発2023

    • Author(s)
      河上緒、鴻江真維、大谷麗子、陸雄一、吉田眞理、野中隆、長谷川成人
    • Organizer
      第42回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] 神経変性疾患を予防するワクチンの開発:αシヌクレイン凝集体の立体構造に基づく新規ワクチンの作製2023

    • Author(s)
      野中隆、大谷麗子、長谷川成人
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] アデノ随伴ウイルス発現系を用いた筋萎縮性側索硬化症のモデル開発2022

    • Author(s)
      高瀬未菜、橋本雅史、大谷麗子、木村妙子、毛内拡、野中隆、長谷川成人
    • Organizer
      第41回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] 液-液相分離はTDP-43凝集体形成に関与するか?2022

    • Author(s)
      勇亜衣子、大谷麗子、渡辺亮平、野中隆、東晋二、新井哲明、小野寺理、長谷川成人
    • Organizer
      第41回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] αシヌクレイン凝集体の立体構造に基づく 新規ワクチンの作製2022

    • Author(s)
      大谷麗子、高瀬未菜、木村妙子、鈴掛雅美、勇亜衣子、毛内拡、小野寺理、野中隆、長谷川成人
    • Organizer
      第41回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] αシヌクレイン病理から迫るパーキンソン病の病態2022

    • Author(s)
      野中隆
    • Organizer
      第63回日本神経学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K07362
  • [Presentation] ALSの原因となるプロフィリン1変異は機能獲得によりTDP-43の蓄積を誘起する2016

    • Author(s)
      田中良法、野中隆、鈴木元治郎、亀谷富由樹、長谷川成人
    • Organizer
      H27年度 ALS病態解明班 成果報告会
    • Place of Presentation
      都市センターホテル(東京都千代田区)
    • Year and Date
      2016-01-26
    • Data Source
      KAKENHI-PROJECT-15K18370
  • [Presentation] Gain-of-function Profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause intracellular TDP-43 aggregation.2016

    • Author(s)
      Tanaka Y, Nonaka T.
    • Organizer
      脳内環境平成27年度冬の班会議
    • Place of Presentation
      京都大学芝蘭会館(京都府京都市)
    • Year and Date
      2016-01-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18370
  • [Presentation] Mutations in the PFN1 gene induce degenerative changes through aggregation of both mutant PFN1 and TDP-43.2016

    • Author(s)
      Tanaka Y, Nonaka T, Suzuki G, Kametani F, Hasegawa M.
    • Organizer
      第14回医学研国際シンポジウム
    • Place of Presentation
      東京都医学総合研究所 (東京都世田谷区)
    • Year and Date
      2016-06-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18370
  • [Presentation] Gain-of-function Profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause intracellular TDP-43 aggregation.2015

    • Author(s)
      Tanaka Y, Nonaka T, Suzuki G, Kametani F, Hasegawa M.
    • Organizer
      Brain Protein Aging and Dementia Control, 1st International Symposium 2015
    • Place of Presentation
      野依記念学術交流館(愛知県名古屋市)
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18370
  • [Presentation] 患者脳内で不溶化したTDP-43のプリオン様性質2015

    • Author(s)
      野中 隆,長谷川成人
    • Organizer
      第15回日本蛋白質科学会年会
    • Place of Presentation
      あわぎんホール(徳島県徳島市)
    • Year and Date
      2015-06-26
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] Mutations in the PFN1 gene induce degenerative changes through aggregation of both mutant PFN1 and TDP-43.2015

    • Author(s)
      Tanaka Y, Nonaka T, Suzuki G, Kametani F, Hasegawa M.
    • Organizer
      Neuroscience 2015, SfN's 45th annual meeting
    • Place of Presentation
      シカゴ(米国)
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18370
  • [Presentation] 患者脳に出現する異常タンパク質凝集体の細胞間伝播:神経変性疾患の新たな発症メカニズムの可能性2015

    • Author(s)
      野中 隆
    • Organizer
      第45回日本神経精神薬理学会・第37回日本生物学的精神医学会・合同年会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-09-26
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] ALSの原因となるプロフィリン1変異はTDP-43の凝集を誘起する2015

    • Author(s)
      田中良法、野中隆、鈴木元治郎、亀谷富由樹、長谷川成人
    • Organizer
      第41回日本認知症学会
    • Place of Presentation
      リンクステーションホテル青森(青森県青森市)
    • Year and Date
      2015-10-03
    • Data Source
      KAKENHI-PROJECT-15K18370
  • [Presentation] C9ORF72変異型ジペプチドリピート発現によるリン酸化TDP-43の細胞内蓄積2015

    • Author(s)
      野中 隆、鈴木元治郎、亀谷富由樹、長谷川成人
    • Organizer
      第34回日本認知症学会
    • Place of Presentation
      リンクステーションホール青森(青森県青森市)
    • Year and Date
      2015-10-02
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] A novel link between C9ORF72 expansion and phosphorylated TDP-43 aggregation.2015

    • Author(s)
      Takashi Nonaka, Genjiro Suzuki, Fuyuki Kametani and Masato Hasegawa
    • Organizer
      SFN2015
    • Place of Presentation
      Chicago(米国)
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] ALSの原因となるプロフィリン1変異は機能獲得によりTDP-43の凝集を誘起する2015

    • Author(s)
      田中良法、野中隆、鈴木元治郎、亀谷富由樹、長谷川成人
    • Organizer
      認知症研究を知る若手研究者の集まり 2015
    • Place of Presentation
      ニューサンピア高崎(群馬県高崎市)
    • Year and Date
      2015-08-02
    • Data Source
      KAKENHI-PROJECT-15K18370
  • [Presentation] Treatment of cells expressing APP with tau fibrils induces intracellular aggregate formation of tau2014

    • Author(s)
      Takahashi M, Nonaka T, Kametani F, Hisanaga S, Hasegawa M
    • Organizer
      Alzheimer's Association International Conference (AAIC2014)
    • Place of Presentation
      Copenhagen(Denmark)
    • Year and Date
      2014-07-16
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] Prion-like properties of pathological TDP-43 aggregates from diseased brains.2014

    • Author(s)
      Takashi Nonaka
    • Organizer
      Neuroscience 2014
    • Place of Presentation
      パシフィコ横浜(神奈川県,横浜市)
    • Year and Date
      2014-09-11
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] 認知症関連タンパク質のプリオン様性質と細胞モデル2014

    • Author(s)
      野中隆
    • Organizer
      第33回日本認知症学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県,横浜市)
    • Year and Date
      2014-11-29
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] 神経変性疾患の患者脳に蓄積する異常タンパク質の解析2014

    • Author(s)
      野中隆
    • Organizer
      第14回日本蛋白質科学会
    • Place of Presentation
      ワークピア横浜・横浜産貿ホール マリネリア(神奈川県,横浜市)
    • Year and Date
      2014-06-25
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] TDP-43のC末端領域の凝集に関わる配列の同定2014

    • Author(s)
      下中翔太郎,,野中隆,久永真市,長谷川成人
    • Organizer
      第33回日本認知症学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県,横浜市)
    • Year and Date
      2014-11-29
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] Phosphorylation of TDP-43 by casein kinase 1 delta facilitates mislocalization and intracellular aggregate formation of TDP-432014

    • Author(s)
      Takashi Nonaka, Hisao Masai, Masato Hasegawa
    • Organizer
      Alzheimer's Association International Conference (AAIC2014)
    • Place of Presentation
      Copenhagen(Denmark)
    • Year and Date
      2014-07-15
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] APP 発現によるタウ蓄積の亢進2014

    • Author(s)
      高橋宗聖,野中隆,久永真市,長谷川成人
    • Organizer
      第33回日本認知症学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県,横浜市)
    • Year and Date
      2014-11-29
    • Data Source
      KAKENHI-PUBLICLY-26111730
  • [Presentation] PRION-LIKE PROPERTIES OF PATHOLOGICAL TDP-43 AGGREGATES IN DISEASED BRAINS.2013

    • Author(s)
      Nonaka T
    • Organizer
      The 11th International Conference on Alzheimer's Parkinson's Diseases
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2013-03-07
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] メチレンブルーによるリン酸化タウ蓄積抑制効果の検討2012

    • Author(s)
      細川雅人,新井哲明,野中隆,山下万貴子,鈴掛雅美,辻浩史,長谷川成人,秋山治彦
    • Organizer
      第132回 日本薬学会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] TDP-43のシード依存的細胞内凝集体形成2012

    • Author(s)
      野中隆、長谷川成人
    • Organizer
      第53回日本神経学会学術大会、シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2012-05-24
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Intracellular seeding model reproduces characteristic features of affected neurons in TDP-43 proteinopathy.2012

    • Author(s)
      Takashi Nonaka
    • Organizer
      The 8th International Conference on Fronttemporal Dementias
    • Place of Presentation
      Manchester, UK
    • Year and Date
      2012-09-06
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] TDP-43のシード依存的細胞内凝集体形成2012

    • Author(s)
      野中隆
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-24
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] Intracellular seeding model reproduces characteristic features of affected neurons in TDP-43 proteinopathy2012

    • Author(s)
      Takashi Nonaka, Masami Masuda-Suzukake, Yoko Hasegawa,Mari Yoshida, Shigeo Murayama,David Mann, Haruhiko Akiyama and Masato Hasegawa
    • Organizer
      The 8th International Conference on Fronttemporal Dementias
    • Place of Presentation
      Manchester, UK
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] シード依存的な細胞内TDP-43蓄積による細胞死の誘導2012

    • Author(s)
      野中隆,鈴掛(増田)雅美,新井哲明,吉田眞理,村山繁雄,Mann David,秋山治彦,長谷川成人
    • Organizer
      第31回日本認知症学会学術集会
    • Place of Presentation
      筑波
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Intracellular seeded aggregation and cytotoxic model of TDP-432012

    • Author(s)
      Takashi Nonaka, Masami Masuda-Suzukake, Makiko Yamashita, Masato Hosokawa, Haruhiko Akiyama and Masato Hasegawa
    • Organizer
      Alzheimer's Association International Conference (AAIC)2012
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2012-07-16
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] シード依存的な細胞内TDP-43蓄積による細胞死の誘導2012

    • Author(s)
      野中隆
    • Organizer
      第31回日本認知症学会学術集会
    • Place of Presentation
      筑波
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] 患者脳に蓄積したTDP-43のプリオン様性質2012

    • Author(s)
      野中隆
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] 患者脳に蓄積したTDP-43のプリオン様性質2012

    • Author(s)
      野中隆,鈴掛(増田)雅美,新井哲明,吉田眞理,村山繁雄,Mann David,秋山治彦,長谷川成人
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] メチレンブルーによるリン酸化タウ蓄積抑制効果の検討2011

    • Author(s)
      細川雅人、新井哲明、野中隆、山下万喜子、鈴掛雅美、辻浩史、長谷川成人、秋山治彦
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] FTDP-17が疑われた日本人患者75症例におけるPGRNとMAPT 遺伝子解析2011

    • Author(s)
      大垣光太郎、李元哲、高梨雅史、石川景一、小林智則、中西淳、野中隆、長谷川成人、岸 雅彦、吉野浩代、舩山学、塩屋敬一、横地正之、佐々木良元、小久保康昌、葛原茂樹、本井ゆみ子、富山弘幸、服部信孝
    • Organizer
      第5回パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      東京
    • Year and Date
      2011-10-07
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] ALSおよびFTLD-TDPに蓄積するリン酸化TDP-43蛋白コンフォメーションに関する解析2011

    • Author(s)
      辻浩史、長谷川成人、野中隆、亀谷富由樹、山下万喜子、増田雅美、細川雅人、秋山治彦、David Mann、初田裕幸、高尾昌樹、村山繁雄、斉藤祐子、詫間浩、冨所康志、中馬越清隆、石井亜紀子、石井一弘、渡邉雅彦、新井哲明、玉岡晃
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] 神経変性疾患における蛋白癌仮説2011

    • Author(s)
      長谷川成人、野中隆、辻浩史、山下万喜子、増田雅美、玉岡晃、村山繁雄、新井哲明、秋山治彦
    • Organizer
      第52回日本神経学会学術大会、シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] FTLD-TDPおよびALSに蓄積するTDP-43蛋白の凝集体構造に関する解析2011

    • Author(s)
      辻浩史、野中隆、新井哲明、山下万喜子、亀谷富由樹、細川雅人、初田裕幸、高尾昌樹、村山繁雄、斉藤祐子、長谷川成人、秋山治彦、David Mann、詫間浩、玉岡晃
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] TDP-43による運動ニューロン変性の分子病態2011

    • Author(s)
      野中隆、長谷川成人
    • Organizer
      第52回日本神経学会学術大会、シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] 細胞内異常蛋白質の伝播の可能性2011

    • Author(s)
      長谷川成人、野中隆、辻浩史、山下万喜子、増田雅美、玉岡晃、Mann David,村山繁雄、新井哲明、秋山治彦
    • Organizer
      第30回日本認知症学会学術集会、シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Histopathological Analysis of Progranulin Knockout Mice2011

    • Author(s)
      Tetsuaki Arai, Katsuyoshi Mizukami, Masugi Nishihara, Masato Hosokawa, Takashi Nonaka, Masato Hasegawa, Haruhiko Akiyama, Takashi Matsuwaki, Sho Takahashi, Takashi Asada
    • Organizer
      International conference on Alzheimer's disease and related disorders (ICAD) 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-17
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] FTDP-17が疑われた日本人75症例におけるPGRNとMAPT遺伝子解析2011

    • Author(s)
      大垣光太郎、李元哲、高梨雅史、石川景一、小林智則、中西淳、野中隆、長谷川成人、岸雅彦、吉野浩代、舩山学、塩谷敬一、横地正之、佐々木良元、小久保康昌、葛原茂樹、本井ゆみ子、富山弘幸、服部信孝
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Progranulin reduction affects tau phosphorylation in P301L tau transgenic mice2011

    • Author(s)
      M. HOSOKAWA; T. ARAI; T. NONAKA; M. YAMASHITA; M. SUZUKAKE; T. MATSUWAKI; M. NISHIHARA; M. HASEGAWA; H. AKIYAMA
    • Organizer
      Neuroscience 2011
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Quantitative Determination of TDP-43 in Cerebrospinal Fluid of Patients With Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disorders2011

    • Author(s)
      Masato Hosokawa, Haruhiko Akiyama, Tetsuaki Arai, Hiroshi Tsuji, Takashi Nonaka, Makiko Yamashita, Masato Hasegawa
    • Organizer
      International conference on Alzheimer's disease and related disorders (ICAD) 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-17
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Prolonged nitric oxide treatment induces tau aggregation in SH-SY5Y cells2011

    • Author(s)
      Muneaki Takahashi, Takashi Nonaka, Masato Hasegawa, Nobuo Watanabe, Takao Arai
    • Organizer
      SOCIETY FOR FREE RADICAL BIOLOGY AND MEDICINE SFRBM's 18th Annual Meeting
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] TDP-43による運動ニューロン変性の分子病態2011

    • Author(s)
      野中, ら
    • Organizer
      第52回日本神経学会学術大会,シンポジウム
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Cellular models of seeded aggregation of alpha-synuclein and tau2011

    • Author(s)
      Takashi Nonaka, Sayuri T. Watanabe, Takeshi Iwatsubo, Masato Hasegawa
    • Organizer
      International conference on Alzheimer's disease and related disorders (ICAD) 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-17
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Heat shock protein 90 (HSP90) suppresses cell death induced by cytoplasmic TDP-43 and inositol hexakisphosphate kinase 22011

    • Author(s)
      E. NAGATA; T. NONAKA; Y. MORIYA; A. SAIARDI; Y. OKADA; H. TSUKAMOTO; J. ITOH; T. SATOH; T. ARAI; S. TAKIZAWA; F. YOSHII; M. HASEGAWA; S. TAKAGI
    • Organizer
      Neuroscience 2011
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Prolonged nitric oxide treatment induces tau aggregation in SH-SY5Y cells2011

    • Author(s)
      Muneaki Takahashi, Takashi Nonaka, Masato Hasegawa, Nobuo Watanabea, Takao Araia
    • Organizer
      5th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia) 2011
    • Place of Presentation
      Kagoshima, Japan
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] 細胞質内TDP-43凝集体形成細胞でのイノシトール6リン酸キナーゼ2の役割2011

    • Author(s)
      永田栄一郎、野中隆、森谷祐介、岡田義則、佐藤忠之、塚本秀雄、新井哲明、長谷川成人、瀧澤俊也、高木繁治
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] C-terminal TDP-43 Inclusion Suppress Proliferation Mediated by Transcriptional Dysregulation2011

    • Author(s)
      Makiko Yamashita, Takashi Nonaka, Masato Hasegawa, Haruhiko Akiyama
    • Organizer
      International conference on Alzheimer's disease and related disorders (ICAD) 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-17
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Seeded aggregation and toxicity of alpha-synuclein and tau2010

    • Author(s)
      Nonaka, et al
    • Organizer
      Society for Neuroscience Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] 患者脳に蓄積したTDP-43のリン酸化部位に関する検討2008

    • Author(s)
      新井哲明, 長谷川成人, 秋山治彦, 野中隆, 亀谷富由樹, 池田研二, 近藤ひろみ, 下村洋子, 羽賀千恵, 土谷邦秋, 吉田眞理, 橋詰良夫, 新里和弘, 大島健一, 森田光哉, 中野今治
    • Organizer
      第49回日本神経病理学会総会学術研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] TDP-43断片の発現による細胞内凝集体の形成2008

    • Author(s)
      野中隆, 新井哲明, 秋山治彦, 長谷川成人
    • Organizer
      第27回日本認知症学会
    • Place of Presentation
      前橋
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] TDP-43の蓄積を中心とした神経病理2008

    • Author(s)
      新井哲明, 長谷川成人, 野中隆, 亀谷富由樹, 吉田眞理, 橋詰良夫, Beach T, 森田光哉, 中野今治, 織田辰郎, 土谷邦秋, 秋山治彦
    • Organizer
      第27回日本認知症学会
    • Place of Presentation
      前橋
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] TDP-43の細胞内封入体モデルの作製2008

    • Author(s)
      野中隆, 新井哲明, 秋山治彦, 長谷川成人
    • Organizer
      第27回日本認知症学会シンポジウム
    • Place of Presentation
      前橋
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] TDP-43断片の発現による細胞内凝集体の形成.2008

    • Author(s)
      野中隆、他
    • Organizer
      第81回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Presentation] Phosphorylated and ubiquitinated TDP-43 inclusions are recapitulated in SH-SY5Y cells2008

    • Author(s)
      Nonaka T, et al
    • Organizer
      Society for Neuroscience Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] FTDにおけるTDP-43蓄積の意義2008

    • Author(s)
      長谷川成人, 新井哲明, 野中隆 等
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] TDP-43におけるSer409/410の異常リン酸化2008

    • Author(s)
      犬飼有紀, 野中隆, 新井哲明, 吉田眞理, 橋詰良夫, 秋山治彦, 久永眞市, 長谷川成人
    • Organizer
      第27回日本認知症学会
    • Place of Presentation
      前橋
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] Intracellular aggregation of phosphorylated and ubiquit inated TDP-43 in SH-SY5Y cells2008

    • Author(s)
      Nonaka T, et al
    • Organizer
      International Conference on Alzheimer's Disease 2008
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2008-07-27
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] FTLD、ALSに蓄積する異常TDP-43の解析2008

    • Author(s)
      長谷川成人, 新井哲明, 野中隆, 亀谷富由樹, 吉田眞理, 橋詰良夫, Beach T, 森田光哉, 中野今治, 織田辰郎, 土谷邦秋, 秋山治彦
    • Organizer
      第27回日本認知症学会
    • Place of Presentation
      前橋
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] 神経変性疾患におけるリン酸化TDP-43の蓄積2008

    • Author(s)
      新井哲明, 長谷川成人, 秋山治彦, 野中隆, 亀谷富由樹, 池田研二, 近藤ひろみ, 下村洋子, 羽賀千恵, 土谷邦秋, 吉田眞理, 橋詰良夫, 新里和弘, 大島健一, 森田光哉, 中野今治
    • Organizer
      第49回日本神経病理学会総会学術研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] TDP-43の細胞内封入体モデルの作成2008

    • Author(s)
      野中隆、他
    • Organizer
      第27回日本認知症学会
    • Place of Presentation
      前橋
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-20023038
  • [Presentation] αシヌクレインの線維形成におけるA30P凝集核の効果2008

    • Author(s)
      米谷元邦, 犬飼有紀, 野中隆, 久永眞市, 長谷川成人
    • Organizer
      第27回日本認知症学会
    • Place of Presentation
      前橋
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] FTLD、ALSに蓄積する異常TDP-43の解析2008

    • Author(s)
      長谷川成人, 新井哲明, 野中隆, 亀谷富由樹, 吉田眞理, 橋詰良夫, Thomas Beach, 森田光哉, 中野今治, 織田辰郎, 土谷邦秋, 秋山治彦
    • Organizer
      平成20年度特定領域研究「統合脳」夏のワークショップ,合同班会議,統合シンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2008-08-09
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] Phosphorylated and ubiquitinated TDP-43 inclusions are recapitulated in SH-SY5Y cells.2008

    • Author(s)
      Nonaka et al (他5名)
    • Organizer
      Society for Neuroscience Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] 遺伝子変位とFTD : Progranulin遺伝子を含めて2008

    • Author(s)
      新井哲明, 長谷川成人, 西原真杉, 野中隆 等
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] Phosphorylated and ubiquitinated alpha-synuclein forms fibrillar inclusions in SH-SY5Y cells.2007

    • Author(s)
      Nonaka et al (他3名)
    • Organizer
      Society for Neuroscience Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2007-11-07
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] Phosphorylated and ubiquitinated alpha-synuclein forms fibrillar inclusions in SH-SY5Y cells.2007

    • Author(s)
      Nonaka, et. al.
    • Organizer
      Society for Neuroscience Annual Meeting
    • Place of Presentation
      San Diego,USA
    • Year and Date
      2007-11-07
    • Data Source
      KAKENHI-PROJECT-19590297
  • [Presentation] 患者脳に蓄積したTDP-43のプリオン様性質

    • Author(s)
      野中 隆ら
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] 患者脳に蓄積したTDP-43のプリオン様性質

    • Author(s)
      野中 隆ら
    • Organizer
      第32回日本認知症学会学術集会
    • Place of Presentation
      松本
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] 患者脳に蓄積したTDP-43のプリオン様性質

    • Author(s)
      野中隆
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] 患者脳に蓄積したTDP-43のプリオン様性質

    • Author(s)
      野中 隆ら
    • Organizer
      第54回日本神経病理学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] Intracellular seeding model reproduces characteristic features of affected neurons in TDP-43 proteinopathy.

    • Author(s)
      Takashi Nonaka
    • Organizer
      The 8th International Conference on Fronttemporal Dementias
    • Place of Presentation
      Manchester, UK
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] TDP-43のシード依存的細胞内凝集体形成

    • Author(s)
      野中隆
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] PRION-LIKE PROPERTIES OF PATHOLOGICAL TDP-43 AGGREGATES IN DISEASED BRAINS.

    • Author(s)
      Nonaka T
    • Organizer
      The 11th International Conference on Alzheimer's & Parkinson's Disease
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-22500345
  • [Presentation] Insoluble TDP-43 prepared from diseased brains has prion-like properties.

    • Author(s)
      Nonaka T et al
    • Organizer
      Alzheimer's Association International Conference (AAIC2013)
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PUBLICLY-24111556
  • [Presentation] シード依存的な細胞内TDP-43蓄積による細胞死の誘導

    • Author(s)
      野中隆
    • Organizer
      第31回日本認知症学会学術集会
    • Place of Presentation
      筑波
    • Data Source
      KAKENHI-PROJECT-22500345
  • 1.  HASEGAWA Masato (10251232)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 20 results
  • 2.  TANAKA Yoshinori (00747933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 3.  KAMETANI Fuyuki (70186013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 4.  SUZUKI Genjiro (60466034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  HOSOKAWA Masato (00435116)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  Katsuragi Yoshinori (60401759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HIGASHI Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  平井 宏和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  山下 俊英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  長谷川 寿一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  岡戸 晴生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  青木 茂樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  橋本 唯史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  新井 哲明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 15.  秋山 治彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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