kawashima hiroyuki 川島寛之

… Alternative Names

KAWASHIMA Hiroyuki 川島寛之

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Researcher Number	30361900
Other IDs
Affiliation (Current)	2025: 新潟大学, 医歯学系, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 新潟大学, 医歯学系, 教授 2019: 新潟大学, 医歯学系, 准教授 2015 – 2018: 新潟大学, 医歯学系, 講師 2010 – 2013: 新潟大学, 医歯学系, 助教 2007 – 2008: Niigata University, 医歯学系, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator サルコペニア / 筋委縮 / がん骨転移 / スクレロスチン / 原発性骨腫瘍 / 骨破壊 / 破骨細胞 / 軟部腫瘍 / 骨腫瘍 / デノスマブ … More / RANKL / 骨肉腫 / テロメラーゼ / アデノウイルス / ウイルス療法 / 軟部肉腫 / 軟部腫瘍学 / 骨 / real time RT-PCR / 骨軟部腫瘍 / Tissue Micro Array / Western blot / RT-PCR / 間葉系腫瘍 / FUS1 … More Except Principal Investigator 融合遺伝子 / 骨軟部肉腫 / リンパ球 / 免疫治療 / 中間群 / 骨軟部腫瘍 / 再発 / デスモイド腫瘍 / 骨巨細胞腫 / 免疫細胞 / 腫瘍特異的融合遺伝子 / RT-PCR / 循環微量腫瘍細胞 / バイオマーカー / 定量的RT-PCT / 血中循環腫瘍細胞 / 定量的RT-PCR / 遺伝子増幅 / 血中循環微量腫瘍細胞 Less

がん骨転移と筋委縮に対する抗スクレロスチン抗体療法Principal Investigator
- Principal Investigator
  
  川島寛之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Niigata University
良悪性中間群骨軟部腫瘍における免疫環境の解析と新規治療法の開発
- Principal Investigator
  
  生越章
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Niigata University
Elucidation of the mechanism of bone destruction in primary bone tumorsPrincipal Investigator
- Principal Investigator
  
  Kawashima Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
骨軟部肉腫における血中循環腫瘍細胞の新規検出法による予後予測
- Principal Investigator
  
  堀田哲夫
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
Detection of circulating tumor cells targeting tumor specific fusion gene in musculoskeletal sarcoma
- Principal Investigator
  
  Hotta Tetsuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
Virotherapy for bone and soft tissue sarcoma by telomerase-specific oncolytic adenovirusPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
Systemic Gene Therapy for Osteosarcoma by Tumor Suppressor Gene Fus1Principal Investigator
- Principal Investigator
  
  KAWASHIMA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University

All 2022 2019 2018 2017 2016 2015 2013 2011 2010 2008 2007

All Journal Article Presentation

[Journal Article] NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma2022
- Author(s)
  Murayama Y, Kasahara Y, Kubo N, Shin C, Imamura M, Oike N, Ariizumi T, Saitoh A, Baba M, Miyazaki T, Suzuki Y, Ling Y, Okuda S, Mihara K, Ogose A, Kawashima H, Imai C.
- Journal Title
  
  Transl Oncol
  
  Volume: 25 Pages: 101521-101521
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09197
[Journal Article] Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia2019
- Author(s)
  Inagawa Yuta、Komeno Yukiko、Saito Satoshi、Maenohara Yuji、Yamagishi Tetsuro、Kawashima Hiroyuki、Saito Taku、Abe Keiko、Iihara Kuniko、Hatada Yasumasa、Ryu Tomiko
- Journal Title
  
  Case Reports in Hematology
  
  Volume: 2019 Pages: 1-7
- DOI
  10.1155/2019/1616237
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10960, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Expression Profiling of Receptor-Activator of Nuclear Factor-Kappa B Ligand in Soft Tissue Tumors2019
- Author(s)
  Yamagishi T, Kawashima H, Ogose A, Ariizumi T, Oike N, Sasaki T, Hatano H, Ohashi R, Umezu H, Ajioka Y, Endo N.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 248 Issue: 2 Pages: 87-97
- DOI
  10.1620/tjem.248.87
- NAID
  130007662277
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08691, KAKENHI-PROJECT-17K10960
[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical Abnormalities in Soft Tissue Sarcoma : A Comparative Study in Patients with Benign and Malignant Soft Tissue Tumors.2018
- Author(s)
  Ariizumi T, Kawashima H, Ogose A, Sasaki T, Hotta T, Hatano H, Morita T, Endo N.
- Journal Title
  
  Ann Clin Lab Sci.
  
  Volume: 48 Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10849
[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical2018
- Author(s)
  Ariizumi T, Kawashima H, Ogose A, Sasaki T, Hotta T, Hatano H, Morita T, Endo
- Journal Title
  
  Ann Clin Lab Sci
  
  Volume: 48 Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10849
[Journal Article] Denosumab as a potential therapeutic option for leiomyosarcoma with osteoclast?like giant cells: A case report2017
- Author(s)
  Sasaki Taro、Kawashima Hiroyuki、Ariizumi Takashi、Yamagishi Tetsuro、Oike Naoki、Umezu Hajime、Inagawa Shyoichi、Hotta Tetsuo、Endo Naoto、Ogose Akira
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 8 Pages: 30-33
- DOI
  10.3892/mco.2017.1489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10960
[Journal Article] Receptor-Activator of Nuclear KappaB Ligand Expression as a New Therapeutic Target in Primary Bone Tumors2016
- Author(s)
  Yamagishi T, Kawashima H, Ogose A, Ariizumi T, Sasaki T, Hatano H, Hotta T, Endo N
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0154680-e0154680
- DOI
  10.1371/journal.pone.0154680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10849
[Journal Article] Effect of temozolomide on the viability of musculoskeletal sarcoma cells.2015
- Author(s)
  Kusabe Y, Kawashima H, Ogose A, Sasaki T, Ariizumi T, Hotta T, Endo N.
- Journal Title
  
  Oncology letters
  
  Volume: 10 Pages: 2511-2518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462325
[Journal Article] Telomelysin shows potent antitumor activity through apoptotic and non-apoptotic cell death in soft tissue sarcoma cells.2013
- Author(s)
  Li GD, Kawashima H, Ogose A, Ariizumi T, Hotta T, Kuwano R, Urata Y, Fujiwara T, Endo N
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 9 Pages: 1178-1188
- DOI
  10.1111/cas.12208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462325
[Journal Article] Telomelysin exhibits potent anti-tumor activity via apoptotic and non-apoptotic cell death in softtissue sarcoma cells2013
- Author(s)
  Guidong Li, Hiroyuki Kawashima, et al
- Journal Title
  
  Cancer Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689040
[Journal Article] Efficient virotherapy for osteosarcoma by telomerase-specific oncolytic adenovirus2011
- Author(s)
  Guidong Li, Hiroyuki Kawashima, et al
- Journal Title
  
  J Cancer ResClin Oncol
  
  Volume: 137 Issue: 6 Pages: 1037-1051
- DOI
  10.1007/s00432-010-0969-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689040
[Journal Article] Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells2007
- Author(s)
  Deng WG, Kawashima H, Wu G, et al.
- Journal Title
  
  Cancer Research 67
  
  Pages: 709-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791021
[Presentation] 良悪性境界病変に対する治療戦略デスモイド以外の中間性軟部腫瘍に対する分子細胞遺伝学的診断2018
- Author(s)
  川島寛之, 生越章, 有泉高志, 山岸哲郎, 大池直樹, 堀田哲夫, 遠藤直人, 佐々木太郎, 畠野宏史
- Organizer
  第67回東日本整形災害外科学会
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 巨細胞腫における免疫担当細胞の浸潤状況2018
- Author(s)
  大池直樹、川島寛之、生越章、堀田哲夫、有泉高志、畠野宏史、山岸哲郎、遠藤直人
- Organizer
  第91回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10960
[Presentation] 脂肪系腫瘍の鑑別における微量検体からのRNAを用いたreal-time PCRによる遺伝子発現の有用性2017
- Author(s)
  山岸哲郎, 川島寛之, 生越章, 有泉高志, 大池直樹, 佐々木太郎, 畠野宏史, 堀田哲夫, 遠藤直人
- Organizer
  第50回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 骨・軟部腫瘍におけるスタニオカルシン-1の発現2017
- Author(s)
  山岸哲郎, 川島寛之, 有泉高志, 生越章, 大池直樹, 佐々木太郎, 畠野宏史, 堀田哲夫, 遠藤直人
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 転移性骨腫瘍例における原発巣別デノスマブの効果2017
- Author(s)
  有泉高志、川島寛之、山岸哲郎、大池直樹、堀田哲夫、遠藤直人、生越章、畠野宏史、佐々木太郎
- Organizer
  第90回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10960
[Presentation] デノスマブ投与後に脊椎全摘術を施行した腰椎骨巨細胞腫の1例2017
- Author(s)
  湊圭太郎、平野徹、渡辺慶、大橋正幸、川島寛之、有泉高志、山岸哲郎、遠藤直人、生越章
- Organizer
  第113回東北整形災害外科学会
- Data Source
  KAKENHI-PROJECT-17K10960
[Presentation] 骨・軟部腫瘍におけるスタニオカルシンー１の発現2016
- Author(s)
  川島寛之、山岸哲郎、有泉高志、堀田哲夫、遠藤直人、生越章
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 針生検での微量検体RNAを用いたreal-time PCRによる遺伝子解析　脂肪腫と高分化型脂肪肉腫の比較2016
- Author(s)
  佐々木太郎、畠野宏史、大池直樹、小林宏人、川島寛之、有泉高志、山岸哲郎、堀田哲夫、生越章、遠藤直人
- Organizer
  第49回日本整形外科学会　骨・軟部腫瘍学術集会
- Place of Presentation
  東京ドームホテル（東京都文京区）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-16K10849
[Presentation] 軟部腫瘍における治療標的としてのRANKL関連分子の発現解析2015
- Author(s)
  山岸哲郎, 生越章, 川島寛之, 佐々木太郎, 堀田哲夫, 遠藤直人, 梅津哉, 畠野宏史, 有泉高志
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462325
[Presentation] 脂肪腫と高分化型脂肪肉腫に対する針生検での微量検体RNAを用いたreal-time PCRによる遺伝子解析2013
- Author(s)
  佐々木太郎, 生越章, 川島寛之, 有泉高志, 堀田哲夫, 田中恵子, 遠藤直人
- Organizer
  第46回日本整形外科学会　骨・軟部腫瘍学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25462325
[Presentation] Telomerase-specific oncolytic adenovirus exhibits potent anti-tumor activity, via induction of both apoptotic and non-apoptotic cell death in soft tissue sarcoma cells2011
- Author(s)
  Guidong Li, Hiroyuki Kawashima, et al
- Organizer
  16^<th> ISOLS general meeting
- Place of Presentation
  Beijing, China
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22689040
[Presentation] ヒト骨肉腫細胞株およびマウス移植モデルにおけるテロメラーゼ特異的制限増殖型ウイルスの抗腫瘍効果2010
- Author(s)
  李貴東、川島寛之ほか
- Organizer
  第43回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-22689040
[Presentation] ヒト軟部肉腫におけるテロメラーゼ特異的制限増殖型アデノウイルス、テロメライシン(OBP-301)の抗腫瘍効果2010
- Author(s)
  李貴東、川島寛之ほか
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22689040
[Presentation] Telomerase-specific oncolytic virotherapy for osteosarcoma2010
- Author(s)
  Hiroyuki Kawashima, et al
- Organizer
  101^<st> AACR annual meeting
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-22689040
[Presentation] Overcoming gefitinib/erlotinib-induced resistance by tumor suppressor fus1-madiated downregulation of met/akt signaling in human lung cancer2008
- Author(s)
  Deng W, Kawashima H, et al.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19791021
[Presentation] Nanoparticla-mediated delivery of therapeutic peptide derived from novel tumor suppressor FUS1 protein for human lung cancer treatment2007
- Author(s)
  Deng W, Uno F, Wu G, Kawashima H, et al.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Los Angeles
- Data Source
  KAKENHI-PROJECT-19791021
[Presentation] Interaction of tumor suppressor FUS1 with nuclear receptor tyrosine kinase RAR-alpha proteins enhances the sensitivity of non-small cell lung cancer (NSCLC) to retinoid-mediated therapy2007
- Author(s)
  Iwamaru A, Deng W, Kawashima H, et al.
- Organizer
  Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Los Angeles
- Data Source
  KAKENHI-PROJECT-19791021

1. Hotta Tetsuo (00272815)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. 有泉高志 (50571915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 生越章 (80323963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 大池直樹 (20961676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 湊圭太郎 (90970608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SASAKI Taro

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. YAMAGISHI Tetsuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

kawashima hiroyuki 川島 寛之

KAWASHIMA Hiroyuki 川島 寛之

Research Projects

Research Products

Co-Researchers

がん骨転移と筋委縮に対する抗スクレロスチン抗体療法Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

良悪性中間群骨軟部腫瘍における免疫環境の解析と新規治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of bone destruction in primary bone tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨軟部肉腫における血中循環腫瘍細胞の新規検出法による予後予測

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of circulating tumor cells targeting tumor specific fusion gene in musculoskeletal sarcoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Virotherapy for bone and soft tissue sarcoma by telomerase-specific oncolytic adenovirusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Systemic Gene Therapy for Osteosarcoma by Tumor Suppressor Gene Fus1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma2022

Author(s)

Journal Title

Data Source

[Journal Article] Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression Profiling of Receptor-Activator of Nuclear Factor-Kappa B Ligand in Soft Tissue Tumors2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical Abnormalities in Soft Tissue Sarcoma : A Comparative Study in Patients with Benign and Malignant Soft Tissue Tumors.2018

Author(s)

Journal Title

Data Source

[Journal Article] The Diagnostic and Prognostic Value of Hematological and Chemical2018

Author(s)

Journal Title

Data Source

[Journal Article] Denosumab as a potential therapeutic option for leiomyosarcoma with osteoclast?like giant cells: A case report2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Receptor-Activator of Nuclear KappaB Ligand Expression as a New Therapeutic Target in Primary Bone Tumors2016

Author(s)

Journal Title

kawashima hiroyuki 川島寛之

KAWASHIMA Hiroyuki 川島寛之

[Presentation] 良悪性境界病変に対する治療戦略デスモイド以外の中間性軟部腫瘍に対する分子細胞遺伝学的診断2018

[Presentation] 針生検での微量検体RNAを用いたreal-time PCRによる遺伝子解析　脂肪腫と高分化型脂肪肉腫の比較2016