INOUE Kazuhiko 井上和彦

Researcher Number	30363641
Other IDs
Affiliation (based on the past Project Information) *help	2017: 和歌山信愛女子短期大学, その他部局等, 講師 2015 – 2016: 鹿児島大学, 医歯学域医学系, 助教 2013 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 助教 2011: 鹿児島大学, 大学院・医歯学総合研究科, 助教 2010 – 2011: 鹿児島大学, 医歯学総合研究科, 助教 … More 2009: 鹿児島大学, 大学院・医歯学総合研究科, 助教 2007: Kagoshima University, Graduate School of Medical and Dental Sciences, Assistant Professor 2006: 鹿児島大学, 大学院医歯学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Eating habits Except Principal Investigator Endocrinology
Keywords	Principal Investigator Gタンパク質共役型受容体 / 酸化LDL / 血管内皮細胞 / 平滑筋細胞 / マクロファージ / 脂質 / リン脂質 / 味細胞 / 3次元培養 / スフェロイド … More Except Principal Investigator … More 下垂体 / PACAP / 神経ペプチド / 遺伝子発現 / アデニル酸シクラーゼ / 精巣 / 転写因子 / 生殖系細胞 / 生殖内分泌学 / PAC1 / 視床下部 / 摂食 / glycogen / アストロサイト / 生理活性ペプチド / 神経内分泌 / 内分泌 / pituitary / adenvlate cvclase / neuronentide / gene exnression / testis / transcrintion factor / germinal cell Less

Development of a novel taste cell culture systemPrincipal Investigator
- Principal Investigator
  
  INOUE Kazuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Eating habits
- Research Institution
  Wakayama Shin-ai Women's Junior College
  Kagoshima University
Pathophysiologic significance of PACAP in hypothalamus
- Principal Investigator
  
  Miyata Atsuro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kagoshima University
Testis-specific production and its physiological significance of PACAP
- Principal Investigator
  
  MIYATA Atsuro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kagoshima University
Gタンパク質共役型酸化LDL受容体のクローニングと動脈硬化症における役割Principal Investigator
- Principal Investigator
  
  井上和彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kagoshima University
Testis specific regulatory mechanism of human PACAP gene expression
- Principal Investigator
  
  MIYATA Atsuro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kagoshima University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Establishment of disseminated intravascular coagulation (DIC) model by a single iv administration of Escherichia coli-derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of its pathophysiological status.2017
- Author(s)
  Minomo H, Inoue K, Sakaki S, Okazaki T, Kobayashi K, Inoue K, Miyata A.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 133(2) Pages: 88-95
- DOI
  10.1016/j.jphs.2017.01.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12343, KAKENHI-PROJECT-17K08599
[Journal Article] Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice.2016
- Author(s)
  Ohnou T, Yokai M, Hasegawa-Moriyama M, Shimizu T, Inoue K, Kambe Y, Kanmura Y, Miyata A
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 1 Pages: 1-10
- DOI
  10.1016/j.jphs.2016.01.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462383, KAKENHI-PROJECT-25460723, KAKENHI-PROJECT-25461390, KAKENHI-PROJECT-25462225, KAKENHI-PROJECT-25293328, KAKENHI-PROJECT-15K12343
[Journal Article] Chronic overproduction of ghrelin in the hypothalamus leads to temporal increase in food intake and body weight.2015
- Author(s)
  Qi Y*, Inoue K*, Fu M, Inui A, Herzog H. (*These people contributed equally.)
- Journal Title
  
  Neuropeptides
  
  Volume: 50 Pages: 23-28
- DOI
  10.1016/j.npep.2015.02.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12343
[Journal Article] Functional Characterization of Neural-Restrictive Silencer Element in Mouse Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Gene Expression2014
- Author(s)
  Sugawara H, Tominaga A, Inoue K, Takeda Y, Yamada K, Miyata A
- Journal Title
  
  J Mol Neurosci
  
  Volume: 54 Pages: 526-534
- DOI
  10.1007/s12031-014-0348-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461390, KAKENHI-PROJECT-26462384
[Journal Article] Pituitary adenylate cyclase-activating polypeptide type 1 receptor (PAC1) gene is suppressed by transglutaminase 2 activation.2013
- Author(s)
  Miura A, Kambe Y, Inoue K, Tatsukawa H, Kurihara T, Griffin M, Kojima S, Miyata A.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288(45) Pages: 32720-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461390
[Journal Article] N-arachidonoyl glycine induces macrophage apoptosis via GPR182012
- Author(s)
  Takenouchi R, Inoue K, Kambe Y, Miyata A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418 Pages: 366-71
- DOI
  10.1016/j.bbrc.2012.01.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591182
[Journal Article] Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide(PACAP) gene2011
- Author(s)
  Tominaga A, Sugawara H, Futagawa T, Inoue K, Sasaki K, Minamino N, Hatakeyama M, Handa H, Miyata A.
- Journal Title
  
  Genes to Cells
  
  Volume: 15(6) Pages: 595-606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591182
[Journal Article] Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide(PACAP)gene.2010
- Author(s)
  Tominaga A, Inoue K, Miyata A, (9人中9番目)
- Journal Title
  
  Genes to Cells
  
  Volume: 15(6) Pages: 595-606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591182
[Journal Article] Alternative Splicing of the Pituitary Adenylate Cyclase-activating Polypetide(PACAP) Receptor Contributes to Function of PACAP-272010
- Author(s)
  Ushiyama M, Ikeda R, Yoshida M, Mori K, Kangawa K, Sugawara H, Inoue K, Yamada K, Miyata A.
- Journal Title
  
  Journal of Molecular Neuroscience
  
  Volume: 42(3) Pages: 341-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591182
[Journal Article] Regulatory mechanism of PAC1 gene expression via Sp1 by Nerve Growth Factor in PC12 cells
- Author(s)
  Miura A, Odahara N, Tominaga A, Inoue K, Kambe Y, Kurihara T, Miyata A.
- Journal Title
  
  FEBS Letters
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] 下垂体腺腫におけるGPR34を介したプロラクチン産生機構2016
- Author(s)
  井上和彦
- Organizer
  第13回GPCR研究会
- Place of Presentation
  日本科学未来館 (東京都江東区)
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K12343
[Presentation] 下垂体腺腫におけるリゾホスファチジルセリンの分子動態2015
- Author(s)
  井上和彦、宮田篤郎
- Organizer
  第8回トランスポーター研究会九州部会
- Place of Presentation
  鹿児島大学（鹿児島県鹿児島市）
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PROJECT-15K12343
[Presentation] 下垂体腺腫細胞GH3のプロラクチンおよび成長ホルモン分泌に及ぼすリゾホスファチジルセリンの効果2014
- Author(s)
  井上和彦、竹ノ内里奈、國師恵美子、大和麻耶、神戸悠輝、宮田篤郎
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  北九州市　産業医科大学
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25461390
[Presentation] 有痛性神経障害患者血清のマウスへの受動態移入による疼痛様行動の再現2014
- Author(s)
  福留学、井上隆之、宮田篤郎、結城伸泰、栗原崇
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  北九州市　産業医科大学
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25461390
[Presentation] Acute activation of astrocytes in spinal dorsal horn VIP PAC1 receptor is involved in PACAP-induced persistent aversive behavior.2013
- Author(s)
  Miyata A, Yokai M, Ohno T, Hasegawa M, Kambe Y, Inoue K, Kamimura Y, Shimizu T, Kurihara T.
- Organizer
  The 11th International Symposium on VIP,PACAP and Related Peptides,
- Place of Presentation
  Pecs, HUNGARY
- Data Source
  KAKENHI-PROJECT-25461390
[Presentation] N-arachidonoyl glycine (NAGly)により誘導されるマクロファージのアポトーシスはGPR18を介している2012
- Author(s)
  竹ノ内里奈、井上和彦、神戸悠輝、栗原崇、宮田篤郎
- Organizer
  日本薬理学会年会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] リゾフォスファチジルセリンのラット下垂体由来細胞における成長ホルモン分泌への促進効果に関する研究2011
- Author(s)
  國師恵美子、竹ノ内里奈、大和麻耶、井上和彦、神戸悠輝、宮田篤郎
- Organizer
  薬物活性シンポジウム
- Place of Presentation
  福岡市
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Lysophosphatidylserine P promotes the Secreion of Growth Hormone in Rat Pituitary Cells via G protein-coupled Receptor2011
- Author(s)
  R.Takenouchi, K.Inoue, E.Kokushi, M.Yamato, Y.Kambe, T.Kurihara, A.Miyata
- Organizer
  GPCR Satellite Symposium of International Symposium on VIP-PACAP and Related Peptides
- Place of Presentation
  イスラエル・エイラト
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Involvement of mitochondria in PACAPPAC1 dependent neurite outgrowth2011
- Author(s)
  Yuki Kambe, Kazuhiko Inoue, Takashi Kurihara, Atsuro Miyata
- Organizer
  10th International Symposium on VIP-PACAP and related peptides
- Place of Presentation
  イスラエル・エイラト
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Sp1 is involved in not only positively but also negatively expression of PAC1 gene2011
- Author(s)
  Ayako Miura, Yuki Kambe, Kazuhiko Inoue, Takashi Kurihara, Atsuro Miyata
- Organizer
  10th International Symposium on VIP-PACAP and related peptides
- Place of Presentation
  イスラエル・エイラト
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Neuro2a細胞におけるERストレスによるPAC1遺伝子の負の発現調節機序2011
- Author(s)
  三浦綾子、井上和彦、神戸悠輝、栗原崇、宮田篤郎
- Organizer
  日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Functional analysis of N-arachidonoyl Glycine as anovel anti-inflammatory factor in microglia2011
- Author(s)
  Rina Takenouchi, Kazuhiko Inoue, Maya Yamato, Atsuro Miyata, Annual Meeting of Society for Nueroscience
- Organizer
  Annual Meeting of Society for Nueroscience
- Place of Presentation
  米国・ワシントン
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Characterization of The testis specific promoter region in humam pituitary adenylate cyclase-activating polypeptide(PACAP) gene.2010
- Author(s)
  Miyata A, Tominaga A, Inoue K, Minamino N, (6人中1番目)
- Organizer
  ENDO EXPO 2010
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] PC12細胞におけるPAC1遺伝子の正と負の調節機序について2010
- Author(s)
  三浦綾子、富永愛子、井上和彦、宮田篤郎, (6人中6番目)
- Organizer
  日本分子生物学会年会・日本生化学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] PC12細胞において神経保護作用を示すPAC 1遺伝子発現におけるNGFの関与2010
- Author(s)
  三浦綾子、富永愛子、神戸悠輝、井上和彦、宮田篤郎
- Organizer
  第7回 GPCR研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] マクロファージにおけるN-arachidonyl glycine(NAGly)の性状解析2010
- Author(s)
  竹ノ内里奈、井上和彦、神戸悠輝、宮田篤郎
- Organizer
  第7回 GPCR研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] 共役リノール酸受容体の同定2010
- Author(s)
  井上和彦、桐原みらい、竹之内里奈、宮田篤郎, (6人中6番目)
- Organizer
  日本分子生物学会年会・日本生化学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Implication of pituitary adenylate cyclase-activating polypeptide (PACAP) in diabethic neuropathy of streptozotocin (STZ) treated mice2010
- Author(s)
  Miyata A, Ikeda K, Inoue K, Kurihara T, Shimizu T
- Organizer
  5^<th> International Peptide Symposium
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] 痛覚伝達におけるPACAP特異的受容体PAC 1の役割2010
- Author(s)
  宮田篤郎、大納哲也、坂本光、井上和彦, (6人中1番目)
- Organizer
  第7回 GPCR研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Implication of pituitary adenylate cyclase-activating polypeptide (PACAP) in diabethic neuropathy of streptozotocin (STZ) treatedmice2010
- Author(s)
  Miyata A, Ikeda K, Inoue K, Kurihara T, Shimizu T
- Organizer
  20^<th>Japan-Korea Joint Seminar on Pharmacology
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] Regulatory mechanism of PAC 1 gene expression by nerve growth factor (NGF) in PC12 cells2010
- Author(s)
  Miura A, Tominaga A, Inoue K, Kambe Y, Miyata A
- Organizer
  Annual Meeting of Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] PC12細胞におけるERストレスによるPAC1遺伝子の負の発現調節機序2010
- Author(s)
  三浦綾子、富永愛子、井上和彦、宮田篤郎, (6人中6番目)
- Organizer
  日本薬理学会西南部会
- Place of Presentation
  鹿児島
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] 遊離脂肪酸受容体の新機能～敗血症における役割～2009
- Author(s)
  井上和彦
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591182
[Presentation] 酸性環境による動脈硬化発症メカニズムの解明2008
- Author(s)
  井上和彦
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591032
[Presentation] 酸性環境による動脈硬化発症メカニズムの解明2008
- Author(s)
  井上和彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591032
[Presentation] Acidic extracellular pH promotes atherogenesis2008
- Author(s)
  K. Inoue
- Organizer
  The 80th annual meeting of the Japanese pharmacological society
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591032
[Presentation] PPAR agonist augments G protein-mediated stimulation in macrophages ; identification of a novel pathway via G protein-coupled receptor2007
- Author(s)
  K. Inoue
- Organizer
  The 80th annual meeting of the Japanese pharmacological society
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591032
[Presentation] Gタンパク質を介したPPARyアゴニストによるマクロファージの活性化機構2007
- Author(s)
  井上和彦
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591032
[Presentation] Spinal PACAP-PAC1-receptor signaling pathway induces long-lasting mechanical allodynia through the activation of astrocytes in mice
- Author(s)
  Youkai M, Kurihara T, Asada T, Kambe Y, Inoue K, Miyata A
- Organizer
  Society for Neuroscience 2014
- Place of Presentation
  米国・ワシントン
- Year and Date
  2014-11-20 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-25461390

1. MIYATA Atsuro (60183969)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KANGAWA Kenji (00112417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SHIODA Seiji (80102375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HANDA Hiroshi (80107432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KAMBE Yuki (60549913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. KATSUURA Goro (20401226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TOMINAGA Aiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. SAITO Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKENOUCHI Rina

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. HASEGAWA Maiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 宮山篤郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 30 results
12. 栗原崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 上村裕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INOUE Kazuhiko 井上 和彦

Research Projects

Research Products

Co-Researchers

Development of a novel taste cell culture systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiologic significance of PACAP in hypothalamus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Testis-specific production and its physiological significance of PACAP

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gタンパク質共役型酸化LDL受容体のクローニングと動脈硬化症における役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Testis specific regulatory mechanism of human PACAP gene expression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment of disseminated intravascular coagulation (DIC) model by a single iv administration of Escherichia coli-derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of its pathophysiological status.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic overproduction of ghrelin in the hypothalamus leads to temporal increase in food intake and body weight.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional Characterization of Neural-Restrictive Silencer Element in Mouse Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Gene Expression2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pituitary adenylate cyclase-activating polypeptide type 1 receptor (PAC1) gene is suppressed by transglutaminase 2 activation.2013

Author(s)

Journal Title

Data Source

[Journal Article] N-arachidonoyl glycine induces macrophage apoptosis via GPR182012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide(PACAP) gene2011

Author(s)

Journal Title

Data Source

[Journal Article] Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide(PACAP)gene.2010

Author(s)

Journal Title

Data Source

[Journal Article] Alternative Splicing of the Pituitary Adenylate Cyclase-activating Polypetide(PACAP) Receptor Contributes to Function of PACAP-272010

Author(s)

Journal Title

Data Source

[Journal Article] Regulatory mechanism of PAC1 gene expression via Sp1 by Nerve Growth Factor in PC12 cells

Author(s)

Journal Title

Data Source

[Presentation] 下垂体腺腫におけるGPR34を介したプロラクチン産生機構2016

INOUE Kazuhiko 井上和彦