uehara norihisa 上原範久

… Alternative Names

UEHARA Norihisa 上原範久

Less

Researcher Number	30368211
Other IDs	https://orcid.org/0000-0003-4032-5291
Affiliation (Current)	2024: 九州大学, 歯学研究院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 九州大学, 歯学研究院, 助教 2016 – 2020: 九州大学, 歯学研究院, 助教 2012 – 2015: 九州大学, 歯学研究科(研究院), 助教 2014: 関西医科大学, 医学部, 講師 2007 – 2012: Kansai Medical University, 医学部, 講師 2004 – 2006: 関西医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General surgery / Basic Section 56020:Orthopedics-related / Basic Section 57010:Oral biological science-related / Morphological basic dentistry Except Principal Investigator General surgery / Ophthalmology / Basic Section 50010:Tumor biology-related / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator HDAC inhibitor / breast cancer / Breast cancer / 骨芽細胞 / 骨転移 / 破骨細胞 / 細胞外小胞 / Growth arrest / Histone deacetylase / Pregnancy … More / cell-cell communication / SASP / osteocytes / osteoblast / mechanical stress / senescence / osteocyte / 骨吸収 / 糖化コラーゲン / 酸化ストレス / 骨細胞 / miRNA / 乳癌 / 癌骨転移 / DNA damage / nicotinamide / DNA損傷 / 合成致死 / ニコチンアミド / tumor suppressor / vorinostat / microRNA / inhibitor / HDAC / Apoptosis / p38 MAPK / Apotosis / breast cance / p38MAPK / apoptosis / Cks1 / Skp2 / M arrest / G2 / Histone modification / Epigenetics / Rat / Real-time PCR / Gene expression / Mammary gland / Cell growth / real-time PCR / Microarray / N-methyl-N-nitrosourea / Carcinogenesis / Mammary glands … More Except Principal Investigator Rat / Mammary / N-methyl-N-nitrosourea / MNU / Cancer / アポトーシス / Progesterone / Estrogen / 乳癌 / Duration / Pregnancy / Endocrine disruption / Perinatal / Mouse / Xenoestrogen / Zeranol / 網膜色素変性症 / 視細胞 / Apoptosis / オートファジー / Lewis rat / ラット / 悪性化 / がん / がん悪性化 / 口腔上皮がん / Galectin4 / 細胞接着 / 細胞移動能 / SLPI / progesterone / estrogen / Carcinoma / Endocrinedisruption / Mammmary / Morphometry / TUNEL / Fatty acids / Methylnitrosourea / Arachidonic acid / Retinitis pigmentosa / 網膜変性症 / アラキドン酸 / ENU / 毒性 / 実験動物学 / 眼病理学 / カルパイン阻害剤 / Bafilomycin A1 / Cell death / Autophagy / Breast / sulforaphane / 3-メチルアデニン / バフィロマイシン / 細胞死 / スルフォラファン / 病理学 / ゲノム / 癌 / 遺伝子 / 妊娠 / 予防 / Fatty acid / Stroma / 脂肪酸組成 / 脂肪酸 / 間質 / 乳腺 / メチルニトロソ尿素 / 経産 Less

Mechanical stress response of senescent osteocytes: an intercellular communication between bone resident cells mediated by specific secreted factors.Principal Investigator
- Principal Investigator
  
  上原範久
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kyushu University
Study of the mechanism underlying secretory leukocyte protease inhibitor (SLPI)-induced malignancy of cancer
- Principal Investigator
  
  Mikami Yoshikazu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Niigata University
Bone metastatic breast cancer cell-derived extracellular vesicles block osteoblast mineralization through MAPK signalingPrincipal Investigator
- Principal Investigator
  
  Uehara Norihisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Roles of bone metastatic mammary tumor cell-derived extracellular vesicles in osteoclast differentiation and functionPrincipal Investigator
- Principal Investigator
  
  Uehara Norihisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
Nicotinamide potentiates HDAC inhibitor-induced cytotoxicity in human breast cancer cells through DNA damage accumulationPrincipal Investigator
- Principal Investigator
  
  UEHARA NORIHISA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Disease control of MNU-induced animal models for retinitis pigmentosa by arachidonic acid and its molecular mechanisms
- Principal Investigator
  
  TSUBURA Airo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kansai Medical University
Involvement of autophagy in MNU-induced retinal degeneration model and its molecular control
- Principal Investigator
  
  YOSHIZAWA Katsuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kansai Medical University
Identification of tumor suppressive miRNAs induced by histone deacetylase inhibitor vorinostat in human breast cancer cellsPrincipal Investigator
- Principal Investigator
  
  UEHARA Norihisa
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
Mechanisms of sulforaphane-induced breast cancer cell death via autophagy and its application in cancer treatment
- Principal Investigator
  
  TSUBURA Airo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
Molecular mechanism of vorinostat-induced cytotoxicity in human breast cancer cellsPrincipal Investigator
- Principal Investigator
  
  UEHARA Norihisa
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
Role of mammary stroma in suppression of parity-induced mammary carcinogenesis and its molecular bases
- Principal Investigator
  
  TSUBURA Airo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
Investigation of targets for mammary cancer prevention by comparing DNA-methylation states of virgin and parous rat mammary glands
- Principal Investigator
  
  MATSUOKA Yoichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
経産乳腺の発癌抵抗性獲得におけるエピジェネティクスと遺伝子発現制御機構の解明Principal Investigator
- Principal Investigator
  
  上原範久
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
Establishment of breast cancer prevention protocol based on hormone milieu of pregnancy and elucidation of its molecular mechanisms
- Principal Investigator
  
  TSUBURA Airo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
経産後乳腺における発癌抑制能の獲得とその機構解明に向けた分子生物学的アプローチPrincipal Investigator
- Principal Investigator
  
  上原範久
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kansai Medical University
Effect of perinatal exposure to zeranol on growth and carcinogenesis
- Principal Investigator
  
  SHIKATA Nobuaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kansai Medical University

[Journal Article] Bone metastatic mammary tumor cell-derived extracellular vesicles inhibit osteoblast maturation via JNK signaling2023
- Author(s)
  Uehara Norihisa、Shibusawa Nobuhide、Mikami Yoshikazu、Kyumoto-Nakamura Yukari、Sonoda Soichiro、Kato Hiroki、Yamaza Takayoshi、Kukita Toshio
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 750 Pages: 109821-109821
- DOI
  10.1016/j.abb.2023.109821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09403
[Journal Article] <scp>miR</scp>‐92a‐3p encapsulated in bone metastatic mammary tumor cell?derived extracellular vesicles modulates mature osteoclast longevity2022
- Author(s)
 Uehara Norihisa、Kyumoto‐Nakamura Yukari、Mikami Yoshikazu、Hayatsu Manabu、Sonoda Soichiro、Yamaza Takayoshi、Kukita Akiko、Kukita Toshio
- Journal Title
 
 Cancer Science
 
 Volume: 113 Issue: 12 Pages: 4219-4229
- DOI
 10.1111/cas.15557
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-22K09360, KAKENHI-PROJECT-22K09403
[Journal Article] Osteoblast-derived Laminin-332 is a novel negative regulator of　osteoclastogenesis in bone microenvironments.2017
- Author(s)
  Uehara N, Kukita A, Kyumoto-Nakamura Y, Yamaza T, Yasuda H, Kukita T.
- Journal Title
  
  Lab Invest.
  
  Volume: 97 Issue: 10 Pages: 1235-1244
- DOI
  10.1038/labinvest.2017.55
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10908, KAKENHI-PROJECT-15K11014, KAKENHI-PROJECT-15K11046
[Journal Article] Arachidonic acid supplementation does not affect N-methyl-N-nitrosourea-induced renal preneoplastic lesions in young Lewis rats.2013
- Author(s)
  Yoshizawa K, Emoto Y, Kinoshita Y, Kimura A, Uehara N, Yuri T, Tsubura A.
- Journal Title
  
  Oncol Lett
  
  Volume: 5 Pages: 1112-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592661
[Journal Article] N-Methyl-N -nitrosourea-induced Renal Tumors in Rats: Immunohistochemical Comparison to Human Wilms Tumors2013
- Author(s)
 Yoshizawa K, Kinoshita Y, Emoto Y, Kimura A, Uehara N, Yuri T, Shikata N, Tubura A.
- Journal Title
 
 Journal of Toxicologic Pathology
 
 Volume: 26 Issue: 2 Pages: 141-148
- DOI
 10.1293/tox.26.141
- NAID
 130003362369
- ISSN
 0914-9198, 1881-915X
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-24592661
[Journal Article] Arachidonic acid supplementation during gestational, lactational and post-weaning period rescues retinal degenation in a rodent model.2013
- Author(s)
  Yoshizawa K, Sasaki T, Kuro M, Uehara N, Takada H, Haramura A, Ohara N, Moriguchi T, Tsubura A.
- Journal Title
  
  Br J Nutr
  
  Volume: 109 Issue: 8 Pages: 1424-1432
- DOI
  10.1017/s0007114512003327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592661
[Journal Article] Promoting effect of arachidonic acid supplementation on N-methyl-N-nitrosourea-induced pancreatic acinar cell hyperplasia in young Lewis rats.2013
- Author(s)
  Yoshizawa K, Uehara N, Kimura A, Emoto Y, Kinoshita Y, Yuri T, Takada H, Moriguchi T, Hamazaki T, Tsubura A.
- Journal Title
  
  Oncol Lett
  
  Volume: 5 Pages: 76-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592661
[Journal Article] Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells2012
- Author(s)
  Uehara N, Yoshizawa K, Tsubura A
- Journal Title
  
  Oncology Reports
  
  Volume: (in press) Pages: 105-110
- DOI
  10.3892/or.2012.1758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791263, KAKENHI-PROJECT-24591923
[Journal Article] N-Ethyl-N-Nitrosourea Induces Retinal Photoreceptor Damage in Adult Rats2012
- Author(s)
 Yoshizawa K, Sasaki T, Uehara N, Kuro M, Kimura A, Kinoshita Y, Miki H, Yuri T, Tsubura A.
- Journal Title
 
 Journal of Toxicologic Pathology
 
 Volume: 25 Issue: 1 Pages: 27-35
- DOI
 10.1293/tox.25.27
- NAID
 130001884594
- ISSN
 0914-9198, 1881-915X
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22591954
[Journal Article] Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1in human breast cancer cells2012
- Author(s)
  Uehara N, Yoshizawa K, Tsubura A
- Journal Title
  
  Oncology Reports
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791263
[Journal Article] Requirement of p38 MAPK for a cell-death pathway triggered by vorinostat in MDA-MB-231 human breast cancer cells2012
- Author(s)
  Uehara N, Kanematsu S, Miki H, Yoshizawa K, Tsubura A
- Journal Title
  
  Cancer Letters
  
  Volume: 315(2) Pages: 112-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791263
[Journal Article] N-Ethyl-N-nitrosourea Retinal induces retinal photoreceptor damage in adult rats2012
- Author(s)
  Yoshizawa K, Sasaki T, Uehara N, Kuro M, Kimura A, Kinoshita Y, Miki H, Yuri T, Tsubura A
- Journal Title
  
  J Toxicol Pathol
  
  Volume: 25 Pages: 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] Sulforaphane inhibits the growth or KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice2011
- Author(s)
  Kanematsu S, Yoshizawa K, Uehara N, Miki H, Sasaki T, Kuro M, Lai Y-C, Kimura A, Yuri T, Tsubura A
- Journal Title
  
  Oncol Rep
  
  Volume: 26(3) Pages: 603-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591683
[Journal Article] Corneal damage induced in adult mice by a single intraperitoneal injection of N-ethyl-N-nitrosourea2011
- Author(s)
  Yoshizawa K, Sasaki T, Kuro M, Miki H, Kimura A, Uehara N, Yuri T, Tsubura A
- Journal Title
  
  In Vivo
  
  Volume: 25 Pages: 609-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] Retinal degeneration induced in adult mice by a single intraperitoneal injection of N-ethyl-N-nitrosourea.2011
- Author(s)
  Yoshizawa K, Kuro-Kuwata M, Sasaki T, Lai C, Kanematsu S, Miki H, Kimura-Kawanaka A, Uehara N, Yuri T, Tsubura A.
- Journal Title
  
  Toxicol Pathol
  
  Volume: 39 Issue: 4 Pages: 606-613
- DOI
  10.1177/0192623311402221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice2011
- Author(s)
  Kanematsu S, Yoshizawa K, Uehara N, Miki H, Sasaki T, Kuro M, Lai Y-C, Kimura A, Yuri T, Tsubura A
- Journal Title
  
  Oncol Rep
  
  Volume: 26(3) Pages: 603-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591683
[Journal Article] Corneal damage induced in adult mice by a single intraperitoneal injection of N-ethyl-N-nitrosourea.2011
- Author(s)
  Yoshizawa K, Sasaki T, Kuro M, Miki H, Kimura A, Uehara N, Yuri T, Tsubura A.
- Journal Title
  
  In Vivo
  
  Volume: 25 Pages: 609-616
- URL
  http://iv.iiarjournals.org/content/25/4/609.abstract
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] Calpain inhibition restores basal autophagy and suppresses MNU-induced photoreceptor cell death in mice.2011
- Author(s)
  Kuro M, Yoshizawa K, Uehara N, Miki H, Takahashi K, Tsubura A.
- Journal Title
  
  In Vivo
  
  Volume: 25 Pages: 617-623
- URL
  http://iv.iiarjournals.org/content/25/4/617.abstract
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] ヒストン脱アセチル化酵素阻害剤vorinostatによるp38MAPキナーゼシグナルを介した乳癌細胞死誘導機序2011
- Author(s)
  上原範久, 兼松清果, 三城弥範, 義澤克彦, 螺良愛郎
- Journal Title
  
  乳癌基礎研究
  
  Volume: 20 Pages: 17-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791263
[Journal Article] Retinal degeneration induced in adult mice by a single intraperitoneal injection of N-ethyl-N-nitrosourea2011
- Author(s)
  Yoshizawa K, Kuro-Kuwata M, Sasaki T, Lai C, Kanematsu S, Miki H, Kimura-Kawanaka A, Uehara N, Yuri T, Tsubura A
- Journal Title
  
  Toxicol Pathol
  
  Volume: 39 Pages: 606-613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] Cerebromalacia with epilepsy and cortical blindness in a laboratory Japanese marague(Macaca fuscata).2010
- Author(s)
  Yoshizawa K, Nakao K, Habiro M, Hayashi K, Kuwata M, Uehara N, Yuri T, Nakamura K, Tsubura A.
- Journal Title
  
  Toxicol Pathol
  
  Volume: 38 Pages: 1058-1063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] Autopbagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells.2010
- Author(s)
  Kanematsu S, Uehara N, Miki H, Yoshizawa K, Kawanaka A, Yuri T, Tsubura A.
- Journal Title
  
  Anticancer Res
  
  Volume: 30 Pages: 3381-3390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591683
[Journal Article] Autophagy inhibition enhauces sulforaphane-induced apoptosis in human breast cancer cells2010
- Author(s)
  Kanematsu S, Uehara N, Miki H, Yoshizawa K, Kawanaka A, Yuri T, Tsubura A
- Journal Title
  
  Anticancer Res
  
  Volume: 30(9) Pages: 3381-3390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591683
[Journal Article] Cerebromalacia with epilepsy and cortical blindness in a laboratory Japanese marague (Macaca fuscata).2010
- Author(s)
  Yoshizawa K, Nakao K, Habiro M, Hayashi K, Kuwata M, Uehara N, Yuri T, Nakamura K, Tsubura A.
- Journal Title
  
  Toxicol Pathol
  
  Volume: 38 Issue: 7 Pages: 1058-1063
- DOI
  10.1177/0192623310382561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591954
[Journal Article] Biphasic effect of short-term pregnancy hormone treatment on N-methyl-N-nitrosourea-induced mammary carcinogenesis in young and old rats2009
- Author(s)
  Lai Y-C, Yuri T, Uehara N, Matsuoka Y, Kanematsu S, Tsubura A.
- Journal Title
  
  Mol Med Rep 2(2)
  
  Pages: 213-220
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Biphasic effect of short-term pregnancy hormone treatment on N-methyl-N-nitrosourea-induced mammary carcinogenesis in youngand old rats.2009
- Author(s)
  Lai Y-C, Yuri T, Uehara N, Matsuoka Y, Kanemastu K, Tsubura A.
- Journal Title
  
  Mol Med Rep 2 (2)
  
  Pages: 213-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Biphasic effect of short-term pregnancy hormone treatment on N-methyl-N-nitrosourea-induced mammary carcinogenesis in young and old rats2009
- Author(s)
  Lai, Y-C., Yuri, T., Uehara, N., Matsuoka, Y., Kanematsu, S., and Tsubura, A.
- Journal Title
  
  Mol. Med. Rep. 2
  
  Pages: 213-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591522
[Journal Article] Role of fatty acids in malignancy and visual impairment : Epidemiological evidence and experimental studies2009
- Author(s)
  Tsubura A, Yuri T, Yoshizawa K, Uehara N, Takada H.
- Journal Title
  
  Histol Histopathol 24(2)
  
  Pages: 223-224
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Estrogen and progesterone treatment mimicking pregnancy for protection from breast cancer.2008
- Author(s)
  Tsubura A, Uehara N, Matsuoka Y, Yoshizawa K, Yuri T.
- Journal Title
  
  In Vivo 22(2)
  
  Pages: 191-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Estrogen and progesterone treatment mimicking pregnancy for protection from breast cancer2008
- Author(s)
  Tsubura A, Uehara N, Matsuoka Y, Yoshizawa K, Yuri T.
- Journal Title
  
  In Vivo 22(2)
  
  Pages: 191-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Mesothelin promotes anchorage-independent growth and prevents anoikis via extracellular signal-regulated kinase signaling pathway in human breast cancer cells2008
- Author(s)
  Uehara, N.
- Journal Title
  
  Mol.Cancer Res 6
  
  Pages: 186-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591522
[Journal Article] Estrogen and progesterone treatment mimicking pregnancy for protection from breast cancer2008
- Author(s)
  Tsubura, A., Uehara, N., Matsuoka, Y., Yoshizawa, K., and Yuri, T.
- Journal Title
  
  In Vivo 22
  
  Pages: 191-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591522
[Journal Article] Mesothelin promotes anchorage-independent growth and prevents anoikisvia ERK signaling pathway in human breast cancer cells.2008
- Author(s)
  Norihisa Uehara, Yoichiro Matsuoka, Airo Tsubura
- Journal Title
  
  Morecular Cancer Research 6(2)
  
  Pages: 186-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790947
[Journal Article] Mesothelin promotes anchorage-independent growth and prevents anoikis via ERK signaling pathway in human breast cancer cells.2008
- Author(s)
  Uehara N, Matsuoka Y, Tsubura A.
- Journal Title
  
  Mol Cancer Res 6(2)
  
  Pages: 186-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis.2008
- Author(s)
  Matsuoka Y, Fukamachi K, Uehara N, Tsuda H, Tsubura A.
- Journal Title
  
  Cancer Sci 99(2)
  
  Pages: 309-315
- NAID
  10024002372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Role of fatty aci ds in mali gnancy and visual impairment : Epidemiological evidence and experimental studies.2008
- Author(s)
  Tsubura A, Yuri T, Yoshizawa K, Uehara N, Takada H
- Journal Title
  
  Histol Histopathol 24(2)
  
  Pages: 223-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis2008
- Author(s)
  Matsuoka Y, Fukamachi K, Uehara N, Tsuda H, Tsubura A.
- Journal Title
  
  Cancer Sci 99(2)
  
  Pages: 309-315
- NAID
  10024002372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis2008
- Author(s)
  Matsuoka, Y., Fukamachi, K., Uehara, N., Tsuda, H., and Tsubura, A.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 309-315
- NAID
  10024002372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591522
[Journal Article] Mesothelin promotes anchorage-independent growth and prevents anoikis via ERK signaling pathway in human breast cancer cells2008
- Author(s)
  Uehara N, Matsuoka Y, Tsubura A.
- Journal Title
  
  Mol Cancer Res 6(2)
  
  Pages: 186-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Mesothelin promotes anchorage-independent growth and prevents anoikis via extracellular signal-regulated kinase signaling pathway in human breast cancer cells2008
- Author(s)
  Uehara, N., Matsuoka, Y., and Tsubura, A.
- Journal Title
  
  Mol. Cancer Res. 6
  
  Pages: 186-193
- Data Source
  KAKENHI-PROJECT-19591522
[Journal Article] N-methyl-N-nitrosourea-induced mammary carcinogenesis promoted by short-term treatment with estrogen and progesterone mimicking pregnancy in aged female Lewis rats2007
- Author(s)
  Tsukamoto R, Mikami T, Miki K, Uehara N, Yuri T, Matsuoka Y, Okazaki K, Tsubura A.
- Journal Title
  
  Oncol Rep 18(2)
  
  Pages: 337-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Multistep mouse mammary tumorigenesis through preneoplasia to neoplasia and acquisition of metastatic potential2007
- Author(s)
  Tsubura, A., Yoshizawa, K., Uehara, N., Yuri, T., and Matsuoka, Y.
- Journal Title
  
  Med. Mol. Morphol. 40
  
  Pages: 9-17
- NAID
  10024379323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591522
[Journal Article] Multistep mouse mammary tumorigenesis through preneoplasia to neoplasia and acquisition of metastatic potential.2007
- Author(s)
  Tsubura A, Yoshizawa K, Uehara N, Yuri T, Matsuoka Y
- Journal Title
  
  Med Mol Morphol 40(1)
  
  Pages: 9-17
- NAID
  10024379323
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] 経産乳腺の発癌刺激低感受性に関する研究2007
- Author(s)
  松岡洋一郎, 上原範久, 圦貴司, 塚本麗子, 螺良愛郎
- Journal Title
  
  乳癌基礎研 16
  
  Pages: 23-26
- Data Source
  KAKENHI-PROJECT-19591521
[Journal Article] Parous mammary glands exhibit distinct alterations in gene expression and proliferation responsiveness to carcinogenic stimuli in Lewis rats2006
- Author(s)
  Uehara N, Unami A, Kiyozuka Y, Shikata N, Oishi Y, Tsubura A.
- Journal Title
  
  Oncol Rep (In press)
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] Parous mammary glands exhibit distinct alterations in gene expression and proliferation responsiveness to carcinogenic stimuli in Lewis rats2006
- Author(s)
  Norihisa Uehara, Akira Unami, Yasuhiko Kiyozuka, Nobuaki Shikata, Yuji Oishi, Airo Tsubura
- Journal Title
  
  Oncology Reports 15(4)
  
  Pages: 903-911
- Data Source
  KAKENHI-PROJECT-16790766
[Journal Article] Effects of different durations of estrogen and progesterone treatment on development of N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats.2006
- Author(s)
  Yuri T, Tsukamoto R, Uehara N, Matsuoka Y, Tsubara A
- Journal Title
  
  In Vivo 20(6B)
  
  Pages: 829-836
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] Biphasic effects of zeranol on the growth of estrogen receptor-positive human breast carcinoma cells.2006
- Author(s)
  Yuri T, Tsukamoto R, Miki K, Uehara N, Matsuoka Y, Tsubura A.
- Journal Title
  
  Oncol Rep 16(6)
  
  Pages: 1307-1312
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] Effects of different durations of estrogen and progesterone treatment on development of N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats.2006
- Author(s)
  Yuri T, Tsukamoto R, Uehara N, Matsuoka Y, Tsubura A
- Journal Title
  
  In Vivo 20 (6B)
  
  Pages: 829-836
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] Biphasic effects of zeranol on the growth of estrogen receptor-positive human breast carcinoma cells.2006
- Author(s)
  Yuri T, Tsukamoto R, Miki K, Uehara N, Mtsuoka Y, Tsubura A
- Journal Title
  
  Oncol Rep 16(6)
  
  Pages: 1307-1312
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] Effects of different durations of estrogen and progesterone treatment on development of Nmethyl-Nnitrosourea-induced mammary carcinomas in female Lewis rats.2006
- Author(s)
  Yuri T, Tsukamoto R, Uehara N, Matsuoka Y, Tsubura A.
- Journal Title
  
  In Vivo 20
  
  Pages: 829-836
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] Effects of prepubertal exposure to xenoestrogen on development of estrogen target organs in female CD-1 mice.2005
- Author(s)
  Nikaido Y, Danbara N, Tsujita-Kyutoku M, Yuri T, Uehara N, Tsubura A.
- Journal Title
  
  In Vivo 19(3)
  
  Pages: 487-494
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Effect of prepubertal exposure to xenoestrogen on development of estrogen target organs in female CD-1 mice.2005
- Author(s)
  Nikaido Y, Danbara N, Tsujita-Kyutoku M, Yuri T, Uehara N, Tsubura A
- Journal Title
  
  In Vivo 19(3)
  
  Pages: 487-494
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Dietary factors modifying breast cancer risk and relation to time of intake.2005
- Author(s)
  Tsubura A, Uehara N, Kiyozuka Y, Shikata N.
- Journal Title
  
  J Mammary Gland Biol Neoplasia 10(1)
  
  Pages: 87-100
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Dietary factors modifying breast cancer risk and relation to time of intake2005
- Author(s)
  Tsubura A, Uehara N, Kiyozuka Y, Shikata N
- Journal Title
  
  J Mammary Gland Biol Neoplasia 10(1)
  
  Pages: 87-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Effects of prepubertal exposure to xenoestrogen on development of estrogen target organs in female CD-1 mice.2005
- Author(s)
  Nikaido Y, Danbara N, Tsujita-Kyutoku M, Yuri T, Uehara N, Tsubura A
- Journal Title
  
  In Vivo 19(3)
  
  Pages: 487-494
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Dietary factors modifying breast cancer risk and relation to time of intake.2005
- Author(s)
  Tsubura A, Uehara N, Kiyozuka Y, Shikata N
- Journal Title
  
  J Mammary Gland Biol Neoplasia 10(1)
  
  Pages: 87-100
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Effects of prepubertal zeranol exposure on estrogen target organs and N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.2004
- Author(s)
  Yuri T, Uehara N, Shikata N, Tsubura A, et al.
- Journal Title
  
  In Vivo 18(6)
  
  Pages: 755-762
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Effects of prepubertal zeranol exposure on estrogen target organs and N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.2004
- Author(s)
  Yuri T, Nikaido Y, Shimano N, Uehara N, Shikata N, Tsubura A
- Journal Title
  
  In Vivo 18(6)
  
  Pages: 755-762
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Effects of maternal xenoestrogen exposure on development of the reproductive tract and mammary gland in female CD-1 mouse offspring.2004
- Author(s)
  Nikaido Y, Yoshizawa K, Danbara N, Tsujita-Kyutoku M, Yuri T, Uehara N, Tsubura A
- Journal Title
  
  Reprod Toxicol 18(6)
  
  Pages: 803-811
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Effects of prepubertal zeranol exposure on estrogen target organs and N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.2004
- Author(s)
  Yuri T, Nikaido Y, Shimano N, Uehara N, Shikata N, Tsubura A
- Journal Title
  
  In Vivo 8(6)
  
  Pages: 755-762
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16510047
[Journal Article] Multistep mouse mammary tumorigenesis through preneoplasia to neoplasia and acquisition of metastatic potential.
- Author(s)
  Tsubura A, Yoshizawa K, Uehara N, Yuri T, Matsuoka Y
- Journal Title
  
  Med Mol Morphol (in press)
- NAID
  10024379323
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591361
[Journal Article] Multistep mouse mammary tumorigenesis through preneoplasia to neoplasia and acquisition of metastatic potential.
- Author(s)
  Tsubura A, Yoshizawa K, Uehara N, Yuri T, Matsuoka Y.
- Journal Title
  
  Med Mol Morphol (in press)
- NAID
  10024379323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591361
[Presentation] 骨転移性乳癌細胞由来細胞外小胞に内包されるmiR-92a-3pは成熟破骨細胞の生存を促進する,2023
- Author(s)
  上原範久，久本由香里，三上剛和, 園田聡一朗, 山座孝義, 久木田敏夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09403
[Presentation] 骨転移性乳癌細胞由来細胞外小胞に内包されるmicroRNAと破骨細胞間コミュニケーション2019
- Author(s)
  上原　範久、久本　由香里、久木田　明子、久木田　敏夫
- Organizer
  第37回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-18K09522
[Presentation] Breast cancer cell-derived extracellular vesicle-mediating transfer of miRNAs regulates osteoclast function2019
- Author(s)
  Norihisa Uehara, Yukari Kyumoto, Akiko Kukita, Toshio Kukita
- Organizer
  Cutting Edge of Bone and Mineral Research
- Invited
- Data Source
  KAKENHI-PROJECT-18K09522
[Presentation] 骨転移癌細胞―破骨細胞間コミニュケーションツールとしてのエクソソームの役割2018
- Author(s)
  上原範久, 久本由香里, 久木田明子, 久木田敏夫
- Organizer
  日本解剖学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] 骨転移性乳癌細胞由来細胞外小胞を介した破骨細胞制御2018
- Author(s)
  上原範久、久本由香里、久木田明子、山座孝義、久木田敏夫
- Organizer
  日本解剖学会第74回九州支部学術集会
- Data Source
  KAKENHI-PROJECT-18K09522
[Presentation] Extracellular vesicles from bone metastatic mammary tumor cells facilitate osteoclast formation and bone resorption in vitro2017
- Author(s)
  上原範久, 久本由香里, 久木田　明子, 久木田　敏夫
- Organizer
  日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] マウス骨転移性乳癌細胞由来エクソソームは破骨細胞分化を促進する2016
- Author(s)
  上原　範久、久本由香里、久木田明子、久木田敏夫
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] 分泌型miRNAを介した骨転移性癌細胞-破骨細胞間コミュニケーション2016
- Author(s)
  上原範久、久本由香里、久木田明子、久木田敏夫
- Organizer
  日本解剖学会
- Place of Presentation
  福島
- Year and Date
  2016-03-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] Bone metastatic mammary tumor cell-derived extracellular vesicles as positive regulator of osteoclastogenesis2016
- Author(s)
  上原　範久、久本由香里、久木田明子、久木田敏夫
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] ニコチンアミドはヒストン脱アセチル化酵素阻害剤vorinostat誘導細胞死を増強する2014
- Author(s)
  上原範久、義澤克彦
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24591923
[Presentation] Inhibition of in vitro cell motility and invasive potential by microRNA-148a in human breast cancer cells2013
- Author(s)
  上原範久、義澤克彦
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24591923
[Presentation] アラキドン酸の妊娠期・授乳期投与によるMNU誘発ラット乳癌発生への影響.2012
- Author(s)
  義澤克彦, 佐々木朋, 木村彩子, 三城弥範, 木下勇一, 上原範久, 圦貴司, 守口徹, 螺良愛郎.
- Organizer
  第101回日本病理学会
- Place of Presentation
  京王プラザホテル(東京)
- Data Source
  KAKENHI-PROJECT-24592661
[Presentation] Vorinostat誘導乳癌細胞増殖抑制におけるSkp2、Cks1発現抑制とp27、p21の安定化2012
- Author(s)
  上原範久、義澤克彦、螺良愛郎
- Organizer
  日本病理学会
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24591923
[Presentation] Vorinostat誘導乳癌細胞増殖抑制におけるmiR-148a発現とその役割2012
- Author(s)
  上原　範久
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  北九州市西日本総合展示場
- Data Source
  KAKENHI-PROJECT-24591923
[Presentation] N-methyl-N-nitrosourea誘発ラット膵臓腺房過形成：その特徴とアラキドン酸投与によるプロモーション効果.2012
- Author(s)
  義澤克彦, 上原範久, 榎本祐子, 木下勇一, 守口徹, 浜崎智仁, 螺良愛郎.
- Organizer
  第154回日本獣医学会
- Place of Presentation
  岩手大学（岩手）
- Data Source
  KAKENHI-PROJECT-24592661
[Presentation] MicroRNA-148a suppresses cell migration and invasion in human breast cancer cells: possible involvement of epithelial-mesenchimal transition pathway2012
- Author(s)
  Norihisa Uehara, Katsuhiko Yoshizawa, Ayako Kimura and Airo Tsubura
- Organizer
  日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24591923
[Presentation] Arachidonic acid supplementation during gestational, lactational and post-weaning periods prevents retinal degeration induced by N-methyl-N-nitrosourea in young Lewis rats.2012
- Author(s)
  Yoshizawa K, Sasaki T, Kuro M, Uehara N, Takada H, Harauma A, Ohara N, Moriguchi T, Tsubura A.
- Organizer
  第39回日本毒性学会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-24592661
[Presentation] アラキドン酸のヒト乳癌細胞株移植動物での腫瘍増殖に対する影響.2012
- Author(s)
  佐々木朋, 義澤克彦, 木村彩子, 三城弥範, 木下勇一, 上原範久, 圦貴司, 守口徹, 螺良愛郎.
- Organizer
  第101回日本病理学会
- Place of Presentation
  京王プラザホテル(東京)
- Data Source
  KAKENHI-PROJECT-24592661
[Presentation] HDAC阻害剤vorinostatのヒト乳癌細胞株に対するDNA損傷応答シグナルへの影響2011
- Author(s)
  上原範久
- Organizer
  第100回日本病理学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] Sulforaphaneによるヌードマウス可移植性KPL-1ヒト乳癌細胞株への効果2011
- Author(s)
  兼松清果, 義澤克彦, 佐々木朋, 三城弥範, 畔満喜, 頼彦長, 木村彩子, 上原範久, 圦貴司, 螺良愛郎
- Organizer
  第19回日本乳癌学会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Sulforaphaneによるヌードマウス可移植性KPL-1ヒト乳癌細胞株の増殖抑制2011
- Author(s)
  兼松清果, 義澤克彦, 佐々木朋, 三城弥範, 畔満喜, 頼彦長, 木村彩子, 上原範久, 圦貴司, 螺良愛郎
- Organizer
  第100回日本病理学会
- Place of Presentation
  横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Vorinostat誘導乳癌細胞増殖抑制におけるSkp2、Cks1発現制御を介したp27の安定2011
- Author(s)
  上原範久、義澤克彦、螺良愛郎
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] Calpain inhibition restores basal autophagy and suppresses apoptosis on MNU-induced photoreceptor cell injury in mice2011
- Author(s)
  Kuro M, Yoshizawa K, Uehara N, Miki H, Takahashi K, Tsubura A
- Organizer
  Association for Reseach in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida、USA
- Year and Date
  2011-05-03
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] 皮質盲ならびに癲癇症状を示した実験用ニホンザルの一剖検例.2011
- Author(s)
  義澤克彦,桑田満喜,頼彦長,兼松清果,三城弥範,川中彩子,上原範久,圦貴司,螺良愛郎.
- Organizer
  第99回日本病理学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] Vorinostat誘導乳癌細胞増殖抑制におけるSkp2、Cks1発現制御を介したp27の安定化2011
- Author(s)
  上原範久
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] Sulforaphaneによるヌードマウス可移植性KPL-1ヒト乳癌細胞株の増殖抑制2011
- Author(s)
  兼松清果, 義澤克彦, 佐々木朋, 三城弥範, 畔満喜, 頼彦長, 木村彩子, 上原範久, 圦貴司, 螺良愛郎
- Organizer
  第100回日本病理学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] MNU誘発マウス網膜変性におけるカルパイン阻害剤によるオートファジーの保持と視細胞死の抑制.2011
- Author(s)
  畔満喜,義澤克彦,上原範久,頼彦長,兼松清果,三城弥範,木村彩子,圦貴司,高橋寛二,螺良愛郎.
- Organizer
  第100回日本病理学会横浜
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] Sulforaphaneによるヌードマウス可移植性KPL-1ヒト乳癌細胞株への効果.2011
- Author(s)
  兼松清果, 義澤克彦, 佐々木朋, 三城弥範, 畔満喜, 頼彦長, 木村彩子, 上原範久, 圦貴司, 螺良愛郎
- Organizer
  第19回日本乳癌学会
- Place of Presentation
  仙台
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] エチルニトロソ尿素によるマウス網膜変性症の病理学的特徴.2011
- Author(s)
  義澤克彦,畔満喜,佐々木朋,三城弥範,木村彩子,上原範久,圦貴司,螺良愛郎.
- Organizer
  第100回日本病理学会横浜
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] Retinal degeneration induced in adult mice by a single intraperitoneal injection of N-ethyl-N-nitrosourea. D2011
- Author(s)
  Yoshizawa K, Sasaki T, Kuro M, Miki H, Kimura A, Uehara N, Yuri T, Tsubura A.
- Organizer
  第30回米国毒性病理学会総会
- Place of Presentation
  米国デンバー
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] Identification of tumor suppressive miRNAs induced by histone deacetylase inhibitor vorinostat in human breast cancer cells2011
- Author(s)
  上原範久
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] Calpain inhibition restores basal autophagy and suppresses apoptosis on MNU-induced photoreceptor cell injury in mice.2011
- Author(s)
  Kuro M, Yoshizawa K, Uehara N, Miki H, Takahashi K, Tsubura A.
- Organizer
  Association for Reseach in Vision and Ophthalmology.
- Place of Presentation
  米国フロリダ
- Year and Date
  2011-05-03
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] SulforaphaneのMDA-MB-231ヒト乳癌細胞株におけるオートファジー誘導2010
- Author(s)
  兼松清果, 上原範久, 三城弥範, 桑田満喜, 頼彦長, 川中彩子, 義澤克彦, 圦貴司, 螺良愛郎
- Organizer
  第18回日本乳癌学会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Vorinostatによるp38 MAPKを介したアポトーシス誘導におけるγH2AXの役割2010
- Author(s)
  上原範久
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] Vorinostat induces H2AX phosphorylation through p38 MAPK pathway in human breast cancer cells2010
- Author(s)
  上原範久、螺良愛郎
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] ヒストン脱アセチル化酵素阻害剤による乳癌細胞アポトーシス誘導～p38活性化シグナル経路の解析～2010
- Author(s)
  上原範久、兼松清果、三城弥範、義澤克彦、螺良愛郎
- Organizer
  第99回日本病理学会
- Place of Presentation
  新宿京王プラザホテル
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] ヒストン脱アセチル化酵素阻害剤による乳癌細胞アポトーシス誘導～p38活性化シグナル経路の解析～2010
- Author(s)
  上原範久
- Organizer
  第99回日本病理学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] MDA-MB-231ヒト乳癌細胞株におけるSulforaphaneによるオートファジー誘導とオートファジー阻害剤の効果.2010
- Author(s)
  兼松清果, 上原範久, 三城弥範, 桑田満喜, 頼彦長, 川中彩子, 義澤克彦, 圦貴司, 螺良愛郎
- Organizer
  第99回日本病理学会
- Place of Presentation
  東京
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] MNUマウス誘発網膜変性におけるオートファジーの関与とその制御.2010
- Author(s)
  桑田満喜,上原範久,義澤克彦,頼彦長,兼松清果,三城弥範,川中彩子,圦貴司,螺良愛郎.
- Organizer
  第99回日本病理学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] MDA-MB-231ヒト乳癌細胞株におけるSulforaphaneによるオートファジー誘導とオートファジー阻害剤の効果2010
- Author(s)
  兼松清果, 上原範久, 三城弥範, 桑田満喜, 頼彦長, 川中彩子, 義澤克彦, 圦貴司, 螺良愛郎
- Organizer
  第99回日本病理学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] MNUマウス誘発網膜変性におけるオートファジーの関与とその制御2010
- Author(s)
  桑田満喜, 上原範久, 義澤克彦, 頼彦長, 兼松清果, 三城弥範, 川中彩子, 杁貴司, 螺良愛郎
- Organizer
  第99回日本病理学会学術集会
- Place of Presentation
  東京・京王プラザホテル
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] Requirement of p38 MAPK for a cell-death pathway triggered by vorinostat in MDA-MB-231 human breast cancer cells2010
- Author(s)
  上原範久
- Organizer
  第20回乳癌基礎研究会
- Place of Presentation
  青島パームビーチホテル
- Year and Date
  2010-07-17
- Data Source
  KAKENHI-PROJECT-22791263
[Presentation] 皮質盲ならびに癩痛症状を示した実験用ニホンザルの-剖検例2010
- Author(s)
  義澤克彦, 桑田満喜, 頼彦長, 兼松清果, 三城弥範, 川中彩子, 上原範久, 圦貴司, 螺良愛郎
- Organizer
  第99回日本病理学会学術集会
- Place of Presentation
  東京・京王プラザホテル
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-22591954
[Presentation] MDA-MB-231ヒト乳癌細胞株における Sulforaphane によるオートファジー誘導とオートファジー阻害剤の効果2010
- Author(s)
  兼松清果, 上原範久, 三城弥範, 桑田満喜, 頼彦長, 川中彩子, 義澤克彦, 圦貴司, 螺良愛郎
- Organizer
  第99回日本病理学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] SulforaphaneのMDA-MB-231ヒト乳癌細胞株におけるオートファジー誘導.2010
- Author(s)
  兼松清果, 上原範久, 三城弥範, 桑田満喜, 頼彦長, 川中彩子, 義澤克彦, 圦貴司, 螺良愛郎
- Organizer
  第18回日本乳癌学会
- Place of Presentation
  札幌
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Role of p38MAPK in a cell-death pathway triggered by suberoylanilide hydroxamic acid(SAHA)in human breast cancer cells2009
- Author(s)
  上原範久
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20790940
[Presentation] Sulforaphane による乳癌細胞増殖抑制におけるアポトーシスとオートファジー誘導2009
- Author(s)
  兼松清果, 上原範久, 三城弥範, 桑田満喜, 義澤克彦, 川中彩子, 義澤克彦, 圦貴司, 螺良愛郎
- Organizer
  第41回日本臨床分子形態学会
- Place of Presentation
  神戸国際会議場(神戸)
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Sulforaphaneによる乳癌細胞増殖抑制におけるアポトーシスとオートファジー誘導.2009
- Author(s)
  兼松清果, 上原範久, 三城弥範, 桑田満喜, 義澤克彦, 川中彩子, 義澤克彦, 圦貴司, 螺良愛郎
- Organizer
  第41回日本臨床分子形態学会
- Place of Presentation
  神戸
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Sulforaphane による乳癌細胞増殖抑制におけるオートファジー誘導の役割2009
- Author(s)
  兼松清果, 上原範久, 松岡洋一郎, 螺良愛郎
- Organizer
  第98回日本病理学会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-05-01
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Role of p38MAPK in a celldeath pathway triggered by suberoylanilide hydroxamic acid (SAHA) in human breast cancer cells2009
- Author(s)
  上原範久
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20790940
[Presentation] Sulforaphane の乳癌細胞増殖抑制とオートファジー2009
- Author(s)
  兼松清果, 上原範久, 松岡洋一郎, 螺良愛郎
- Organizer
  第17回日本乳癌学会
- Place of Presentation
  ホテルグランパシフィック(東京)
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] Sulforaphaneの乳癌細胞増殖抑制とオートファジー.2009
- Author(s)
  兼松清果, 上原範久, 松岡洋一郎, 螺良愛郎
- Organizer
  第17回日本乳癌学会
- Place of Presentation
  東京
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] ヒストン脱アセチル化酵素阻害剤によるMAPキナーセシグナルを介した乳癌細胞死誘導機序2009
- Author(s)
  上原範久
- Organizer
  日本病理学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-20790940
[Presentation] Sulforaphaneによる乳癌細胞増殖抑制におけるオートファジー誘導の役割.2009
- Author(s)
  兼松清果, 上原範久, 松岡洋一郎, 螺良愛郎
- Organizer
  第98回日本病理学会
- Place of Presentation
  京都
- Year and Date
  2009-05-01
- Data Source
  KAKENHI-PROJECT-21591683
[Presentation] ヒストン脱アセチル化酵素阻害剤の乳癌細胞増殖抑制機序とp38MAPK活性化の関与2008
- Author(s)
  上原範久
- Organizer
  日本病理学会
- Place of Presentation
  ホテル日航金沢
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20790940
[Presentation] ヒストン脱アセチル化酵素阻害剤の乳癌細胞増殖抑制機序とp38MAPK活性化の関与2008
- Author(s)
  上原範久
- Organizer
  第97回病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19591522
[Presentation] Effects of short-term treatment with estrogen and progesterone mimicking pregnancy on development of MNU-induced mammary carcinomas in aged female Lewis rats2008
- Author(s)
  Lai Y-C, Yuri T, Uehara N, Matsuoka Y, Kanematsu S, Tsubura A.
- Organizer
  The 26th IABCR(Breast Cancer 15 Suppl 1 : 18-19, 2008)
- Place of Presentation
  Kurashiki, Japan
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] 経産乳腺の発癌刺激低感受性に関する研究2008
- Author(s)
  松岡洋一郎, 上原範久, 圦貴司, 螺良愛郎
- Organizer
  第97回日本病理学会(日病会誌 97 : 326, 2008)
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis.2008
- Author(s)
  Matsuoka Y, Uehara N, Yuri T, Tsubura A.
- Organizer
  The 26th IABCR
- Place of Presentation
  Kurashiki, Japan.
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis2008
- Author(s)
  Matsuoka Y, Uehara N, Yuri T, Tsubura A.
- Organizer
  The 26th IABCR(Breast Cancer 15 Suppl 1 : 39-40, 2008)
- Place of Presentation
  Kurashiki, Japan
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] Molecular mechanisms of suberoylanilide hydroxamic acid-induced G2/M arrest in human breast cancer (MDA-MB-231) cells2008
- Author(s)
  上原範久
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20790940
[Presentation] Effects of short-term treatment with estrogen and progesterone mimicking pregnancy on development of MNU-induced mammary car cinomas in aged female Lewis rats.2008
- Author(s)
  Lai Y-C, Yuri T, Uehara N, Matsuoka Y, Kanematus S, Tsubura A.
- Organizer
  The 26th IABCR
- Place of Presentation
  Kurashiki, Japan.
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] Molecular mechanisms of suberoylanilide hydroxamic acidinduced G2/M arrest in human breast cancer (MDA-MB-231) cells2008
- Author(s)
  上原範久
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20790940
[Presentation] ヒストン脱アセチル化酵素阻害剤によるSkp2, Cks1発現制御とp27の安定化2008
- Author(s)
  上原範久
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790940
[Presentation] 若年期短期エストロゲン/プロゲステロン処置によるラット乳腺脂肪酸組成の変動2008
- Author(s)
  頼彦長, 圦貴司, 上原範久, 松岡洋一郎, 螺良愛郎
- Organizer
  第97回日本病理学会(日病会誌 97 :326, 2008)
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] 妊娠・出産による乳腺発癌抑制についての基礎的研究2007
- Author(s)
  松岡洋一郎, 深町勝巳, 上原範久, 圦貴司, 津田洋幸, 螺良愛郎
- Organizer
  第96回日本病理学会(日病会誌 96 : 209, 2007)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] エストロゲン・プロゲステロン投与による乳腺上皮におけるホルモン受容体の発現変化と乳腺発癌への影響2007
- Author(s)
  圦貴司, 塚本麗子, 上原範久, 松岡洋一郎, 螺良愛郎
- Organizer
  第96回日本病理学会(日病会誌 96 : 333, 2007)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591521
[Presentation] ヒストン脱アセチル化酵素阻害剤の乳癌細胞増殖抑制におけるp38MAPK活性化の関与2007
- Author(s)
  上原範久、松岡洋一郎、螺良愛郎
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18790947
[Presentation] Mesothelin過剰発現乳癌細胞株における足場非依存的増殖促進とERKシグナル経路を介したアノイキス抑制機序2007
- Author(s)
  上原範久
- Organizer
  第17回乳癌基礎研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591522
[Presentation] Arachidonic acid supplementation during gestational, lactational and post-weaning periods prevents retinal degeration induced by N-methyl-N-nitrosourea in young Lewis rats.
- Author(s)
  Yoshizawa K, Sasaki T, Kuro M, Uehara N, Takada H, Harauma A, Ohara N, Moriguchi T, Tsubura A.
- Organizer
  第39回日本毒性学会/The 6th Int Cong Asian Soc Toxicol
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-22591954

1. TSUBURA Airo (90098137)

# of Collaborated Projects: 8 results

# of Collaborated Products: 89 results
2. YURI Takashi (50330212)

# of Collaborated Projects: 6 results

# of Collaborated Products: 64 results
3. MATSUOKA Yoichiro (60219409)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
4. YOSHIZAWA Katsuhiko (70548396)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
5. KIMURA Ayako (80548397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
6. KATAKURA Yoshinori (50264106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIKATA Nobuaki (00121939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. Mikami Yoshikazu (80434075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 久本由香里 (40729026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 久木田明子 (30153266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. 久木田敏夫 (70150464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. 早津学 (40468898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 水谷祐輔 (40646238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 津田啓方 (60325470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 福島敦史 (80415281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

uehara norihisa 上原 範久

UEHARA Norihisa 上原 範久

Research Projects

Research Products

Co-Researchers

Mechanical stress response of senescent osteocytes: an intercellular communication between bone resident cells mediated by specific secreted factors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bone metastatic breast cancer cell-derived extracellular vesicles block osteoblast mineralization through MAPK signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of bone metastatic mammary tumor cell-derived extracellular vesicles in osteoclast differentiation and functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nicotinamide potentiates HDAC inhibitor-induced cytotoxicity in human breast cancer cells through DNA damage accumulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of tumor suppressive miRNAs induced by histone deacetylase inhibitor vorinostat in human breast cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of vorinostat-induced cytotoxicity in human breast cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

経産乳腺の発癌抵抗性獲得におけるエピジェネティクスと遺伝子発現制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

uehara norihisa 上原範久

UEHARA Norihisa 上原範久

[Journal Article] Osteoblast-derived Laminin-332 is a novel negative regulator of　osteoclastogenesis in bone microenvironments.2017